Publications: Dr Neil McCarthy
Hedin CR, McCarthy NE, Louis P, Farquharson FM, McCartney S, Stagg AJ, Lindsay JO, Whelan K
(
2021
)
.
Prebiotic fructans have greater impact on luminal microbiology and CD3+ T cells in healthy siblings than patients with Crohn's disease: A pilot study investigating the potential for primary prevention of inflammatory bowel disease
.
Clinical Nutrition
vol.
40
,
(
8
)
5009
-
5019
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Park JE, JebaMercy G, Pazhanchamy K, Guo X, Ngan SC, Liou KCK, Lynn SE, Ng SS et al.
(
2021
)
.
Aging-induced isoDGR-modified fibronectin activates monocytic and endothelial cells to promote atherosclerosis
.
Atherosclerosis
vol.
324
,
58
-
68
.
Panoskaltsis N, McCarthy NE, Stagg AJ, Mummery CJ, Husni M, Arebi N, Greenstein D, Price CL et al.
(
2021
)
.
Immune reconstitution and clinical recovery following anti-CD28 antibody (TGN1412)-induced cytokine storm
.
Cancer Immunology, Immunotherapy
vol.
70
,
(
4
)
1127
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1142
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Panoskaltsis N, McCarthy NE, Knight SC
(
2021
)
.
Myelopoiesis of acute inflammation: lessons from TGN1412-induced cytokine storm
.
Cancer Immunol Immunother
vol.
70
,
(
4
)
1155
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1160
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McCarthy NE, Stagg AJ, Price CL, Mann ER, Gellatly NL, Al-Hassi HO, Knight SC, Panoskaltsis N
(
2020
)
.
Patients with gastrointestinal irritability after TGN1412-induced cytokine storm displayed selective expansion of gut-homing αβ and γδT cells
.
Cancer Immunology Immunotherapy
Tse SW, Tan CF, Park JE, Gnanasekaran J, Gupta N, Low JK, Yeoh KW, Chng WJ et al.
(
2020
)
.
Microenvironmental Hypoxia Induces Dynamic Changes in Lung Cancer Synthesis and Secretion of Extracellular Vesicles
.
Cancers (Basel)
vol.
12
,
(
10
)
Ng SS, Park JE, Meng W, Chen CP, Kalaria RN, Mccarthy NE, Sze SK
(
2020
)
.
Pulsed SILAM Reveals in Vivo Dynamics of Murine Brain Protein Translation
.
ACS Omega
vol.
5
,
(
23
)
13528
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13540
.
Gill US, McCarthy NE
(
2019
)
.
CD4 T cells in hepatitis B virus: "You don't have to be cytotoxic to work here and help"
.
Journal of Hepatology
Gupta N, Park JE, Tse W, Low JK, Kon OL, McCarthy N, Sze SK
(
2019
)
.
ERO1α promotes hypoxic tumor progression and is associated with poor prognosis in pancreatic cancer
.
Oncotarget
vol.
10
,
(
57
)
5970
-
5982
.
Cox SR, Lindsay JO, Fromentin S, Stagg AJ, McCarthy NE, Galleron N, Ibraim SB, Roume H et al.
(
2019
)
.
Effects of Low-FODMAP Diet on Symptoms, Fecal Microbiome, and Markers of Inflammation in Patients With Quiescent Inflammatory Bowel Disease in a Randomized Trial
.
Gastroenterology
Hoti I, McCarthy N, Giles E, Ayada I, Harrow P, Gordon H, Stagg A, Lindsay J
(
2019
)
.
P092 Circulating classical monocytes and intestinal macrophages exhibit reduced response to IL-10 in IBD
.
Journal of Crohn's and Colitis
.
vol.
13
,
s131
-
s132
.
Cox S, Stagg A, Fromentin S, Ehrlich D, McCarthy N, Galleron N, Levenez F, Lomer M et al.
(
2018
)
.
ADWE-09 Low fodmap diet improves functional-like gastrointestinal symptoms but reduces bifidobacteria in quiescent inflammatory bowel disease
.
Gut
.
vol.
67
,
McCarthy NE, Eberl M
(
2018
)
.
Human γδ T-Cell Control of Mucosal Immunity and Inflammation
.
Front Immunol
vol.
9
,
985
-
985
.
MCCARTHY NE, Tyler CJ, Lindsay JO, Stagg AJ, Moser B, Eberl M
(
2017
)
.
Antigen-presenting human γδ T-cells promote intestinal CD4+ T-cell expression of IL-22 and mucosal release of calprotectin
.
Journal of Immunology
McCarthy N, Gordon H, Rahman S, Harrow P, Stagg A, Lindsay J
(
2017
)
.
P059 Mucosal inflammation promotes activation of circulating Vδ2+ T-cells in Crohn's disease
.
J Crohns Colitis
.
vol.
11
,
Giles EM, Sanders TJ, McCarthy NE, Lung J, Pathak M, Macdonald TT, Lindsay JO, Stagg AJ
(
2017
)
.
Regulation of human intestinal T-cell responses by type 1 interferon-STAT1 signaling is disrupted in inflammatory bowel disease
.
Mucosal Immunology
vol.
10
,
(
1
)
184
-
193
.
Petty RD, McCarthy NE, Dieu RL, Kerr JR
(
2016
)
.
MicroRNAs hsa-miR-99b, hsa-miR-330, hsa-miR-126 and hsa-miR-30c: Potential diagnostic biomarkers in natural killer (NK) cells of patients with Chronic Fatigue Syndrome (CFS)/myalgic encephalomyelitis (ME)
.
PLoS ONE
vol.
11
,
(
3
)
McCarthy NE, Hedin CR, Sanders TJ, Amon P, Hoti I, Ayada I, Baji V, Giles EM et al.
(
2015
)
.
Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease
.
Journal of Clinical Investigation
vol.
125
,
(
8
)
3215
-
3225
.
Brugha R, Mushtaq N, McCarthy NE, Stagg AJ, Grigg J
(
2015
)
.
Respiratory tract dendritic cells in paediatric asthma
.
Clin Exp Allergy
vol.
45
,
(
3
)
624
-
631
.
Sanders TJ, McCarthy NE, Giles EM, Davidson KLM, Haltalli MLR, Hazell S, Lindsay JO, Stagg AJ
(
2014
)
.
Increased production of retinoic acid by intestinal macrophages contributes to their inflammatory phenotype in patients with Crohn's disease
.
Gastroenterology
vol.
146
,
(
5
)
Hedin CR, McCarthy NE, Louis P, Farquharson FM, McCartney S, Taylor K, Prescott NJ, Murrells T et al.
(
2014
)
.
Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings
.
Gut
McCarthy NE, Bashir Z, Vossenkämper A, Hedin CR, Giles EM, Bhattacharjee S, Brown SG, Sanders TJ et al.
(
2013
)
.
Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cells
.
J Immunol
vol.
191
,
(
5
)
2752
-
2763
.
Mann ER, McCarthy NE, Peake STC, Milestone AN, Al-Hassi HO, Bernardo D, Tee CT, Landy J et al.
(
2012
)
.
Skin- and gut-homing molecules on human circulating γδ T cells and their dysregulation in inflammatory bowel disease
.
Clin Exp Immunol
vol.
170
,
(
2
)
122
-
130
.
Mann ER, Bernardo D, Al-Hassi HO, English NR, Clark SK, McCarthy NE, Milestone AN, Cochrane SA et al.
(
2012
)
.
Human gut-specific homeostatic dendritic cells are generated from blood precursors by the gut microenvironment
.
Inflamm Bowel Dis
vol.
18
,
(
7
)
1275
-
1286
.
Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC, McCarthy NE, Prescott NJ, Pessoa-Lopes P, Mathew CG et al.
(
2012
)
.
Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota
.
INFLAMMATORY BOWEL DISEASES
vol.
18
,
(
6
)
1092
-
1100
.
Ng SC, Benjamin JL, McCarthy NE, Hedin CRH, Koutsoumpas A, Plamondon S, Price CL, Hart AL et al.
(
2011
)
.
Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease
.
Inflamm Bowel Dis
vol.
17
,
(
10
)
2027
-
2037
.
Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC, McCarthy NE, Hart AL, Kamm MA, Sanderson JD et al.
(
2011
)
.
Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease
.
Gut
vol.
60
,
(
7
)
923
-
929
.
Ng SC, Benjamin JL, McCarthy NE, Hedin CR, Koutsoumpas A, Plamondon S, Price CL, Hart AL et al.
(
2010
)
.
Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease
.
Inflamm Bowel Dis
.
Holden NJ, Bedford PA, McCarthy NE, Marks NA, Ind PW, Jowsey IR, Basketter DA, Knight SC
(
2008
)
.
Dendritic cells from control but not atopic donors respond to contact and respiratory sensitizer treatment in vitro with differential cytokine production and altered stimulatory capacity
.
Clin Exp Allergy
vol.
38
,
(
7
)
1148
-
1159
.
McCarthy NE, Jones HA, Marks NA, Shiner RJ, Ind PW, Al-Hassi HO, English NR, Murray CM et al.
(
2007
)
.
Inhaled allergen-driven CD1c up-regulation and enhanced antigen uptake by activated human respiratory-tract dendritic cells in atopic asthma
.
Clin Exp Allergy
vol.
37
,
(
1
)
72
-
82
.