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Research

Publications: Dr Helen Le Dieu

Aries JA, Davies JK, Auer RL, Hallam SL, Montoto S, Smith M, Sevillano B, Foggo V et al. ( 2020 ) . Clinical Outcome of Coronavirus Disease 2019 in Haemato-oncology Patients . British Journal of Haematology
Rezvani K, Kanfer EJ, Marin D, Gabriel I, Rahemtulla A, Taylor A, Macdonald D, Dazzi F et al. ( 2012 ) . EBMT risk score predicts outcome of allogeneic hematopoietic stem cell transplantation in patients who have failed a previous transplantation procedure . Biol Blood Marrow Transplant vol. 18 , ( 2 ) 235 - 240 .
O'Riain C, O'Shea DM, Yang Y, Le Dieu R, Gribben JG, Summers K, Yeboah-Afari J, Bhaw-Rosen L et al. ( 2009 ) . Array-based DNA methylation profiling in follicular lymphoma . Leukemia vol. 23 , ( 10 ) 1858 - 1866 .
Le Dieu R, Taussig D, Ramsay AG, Mitter R, Lee AM, Lister TA, Gribben JG ( 2009 ) . Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts . Blood vol. 114 , ( 18 ) 3909 - 3916 .
Le Dieu R, Taussig DC, Ramsay AG, Mitter R, Miraki-Moud F, Fatah R, Lee AM, Lister TA et al. ( 2009 ) . Peripheral blood T cells in acute myeloid leukemia (AML) patients at diagnosis have abnormal phenotype and genotype and form defective immune synapses with AML blasts . Blood vol. 114 , ( 18 ) 3909 - 3916 .
Le Dieu R, Taussig D, Lister TA, Gribben JG ( 2009 ) . Negative immunomagnetic selection of T cells from peripheral blood of presentation AML specimens . Journal of Immunological Methods vol. 348 , ( 1-2 ) 95 - 100 .
Gorgun G, Ramsay AG, Holderried TAW, Zahrieh D, Le Dieu R, Liu F, Quackenbush J, Croce C et al. ( 2009 ) . E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction . PNAS vol. 106 , ( 15 ) 6250 - 6255 .
Le Dieu R, Ramsay AG, Taussig D, Mitter R, Gribben JG ( 2008 ) . Differential Gene Expression Profile Identifies the Nature of T Cell Defects in AML Patients at Diagnosis . Blood . vol. 112 ,
Ramsay AG, Johnson AJ, Lee AM, Gorgün G, Le Dieu R, Blum W, Byrd JC, Gribben JG ( 2008 ) . Chronic lymphocytic leukemia T cells show impaired immunological synapse formation that can be reversed with an immunomodulating drug . J Clin Invest vol. 118 , ( 7 ) 2427 - 2437 .
Le Dieu R, Gribben JG ( 2008 ) . Chronic Lymphocytic Leukaemia . Hematopoietic Stem Cell Transplantation , Editors: Soiffer, RJ , Edition. 1 , Springer
Le Dieu R, Taussig D, MacDougal F, Lister A, Gribben JG ( 2007 ) . CD3+/CD56+cells, but not natural killer T cells, are increased in peripheral blood of untreated patients with leukemia . BLOOD . vol. 110 , 538A - 538A .
Le Dieu R, Gribben JG ( 2007 ) . Transplantation in chronic lymphocytic leukemia . Current Hematologic Malignancy Reports vol. 2 , ( 1 ) 56 - 63 .
Le Dieu R, Gribben JG ( 2007 ) . Transplantation in chronic lymphocytic leukemia . Current Hematologic Malignancy Reports vol. 2 , ( 1 ) 56 - 61 .
Sekhar M, Narat S, Le Dieu R, Luqmani A, Hollamby S, Alobaidi M, Hughes G ( 2006 ) . Major obstetric haemorrhage in late termination of pregnancy in eight women . BLOOD . vol. 108 , 89B - 90B .
Le Dieu R, Gribben J ( 2006 ) . Vaccine- and immune-based therapy in chronic lymphocytic leukemia . SEMIN ONCOL vol. 33 , ( 2 ) 220 - 229 .
Le Dieu R, Gribben JG ( 2006 ) . Allogeneic Stem Cell Transplantation for Non-Hodgkin's and Hodgkin's Lymphoma . The lymphomas , Editors: Canellos, GP, Lister, TA, Young, BD , Edition. 2 , W B Saunders Co
Le Dieu R, Gribben J ( 2005 ) . CD40 activation: lessons for HIV immunotherapy from malignancies? . J HIV Ther vol. 10 , ( 3 ) 51 - 55 .
Ledieu R, Gorgun G, Gribben J ( 2005 ) . In vivo demonstration of donor idiotype specific T cells that kill primary CLL cells post allogeneic transplant . Conference: ASH from: 11/2005
Le Dieu R, Bua M, Andreasson C, Olavarria E, Goldman JM, Apperley JF, Maria D ( 2004 ) . Homoharringtonine in combination with imatinib for patients with CML who have achieved partial or complete cytogenetic responses . BLOOD . vol. 104 , 289A - 289A .
Le Dieu R, Luckit J, Sundarasun M ( 2003 ) . Complications of trephine biopsy . Br J Haematol vol. 121 , ( 6 )
Smith J, Goldsmith C, Ward A, LeDieu R ( 2000 ) . IGF-II ameliorates the dystrophic phenotype and coordinately down-regulates programmed cell death . Cell Death and Differentiation vol. 7 , ( 11 ) 1109 - 1118 .