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Research

Publications: Dr Tizong Miao

Symonds ALJ, Busharat Z, Du M, Miao T, Li S, Hou X, Wang P ( 2024 ) . Memory Phenotype Tfh Cells Develop Without Overt Infection and Support Germinal Center Formation and B Cell Responses to Viral Infection . European Journal of Immunology
Miao T, Symonds A, Hickman OJ, Wu D, Wang P, Lemoine N, Wang Y, Linardopoulos S et al. ( 2024 ) . Inhibition of Bromodomain Proteins Enhances Oncolytic HAdVC5 Replication and Efficacy in Pancreatic Ductal Adenocarcinoma (PDAC) Models . International Journal of Molecular Sciences vol. 25 , ( 2 )
Symonds ALJ, Miao T, Busharat Z, Li S, Wang P ( 2022 ) . Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells . Cancer Immunology, Immunotherapy vol. 72 , ( 5 ) 1139 - 1151 .
Taefehshokr N, Miao T, Symonds ALJ, Wang P, Li S ( 2020 ) . Egr2 regulation in T cells is mediated through IFNγ/STAT1 and IL-6/STAT3 signalling pathway . Pathology - Research and Practice vol. 216 , ( 12 )
Symonds AL, Zheng W, Miao T, Wang H, Wang T, Kiome R, Hou X, Li S et al. ( 2020 ) . Egr2 and 3 control inflammation, but maintain homeostasis, of PD-1high memory phenotype CD4 T cells . Life Science Alliance vol. 3 , ( 9 )
Omodho B, Miao T, Symonds ALJ, Singh R, Li S, Wang P ( 2018 ) . Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells . Immunity Inflammation and Disease vol. 6 , ( 2 ) 221 - 233 .
Singh R, Miao T, Symonds ALJ, Omodho B, Li S, Wang P ( 2017 ) . Egr2 and 3 Inhibit T-bet-Mediated IFN-γ Production in T Cells . J Immunol vol. 198 , ( 11 ) 4394 - 4402 .
Miao T, Symonds ALJ, Singh R, Symonds JD, Ogbe A, Omodho B, Zhu B, Li S et al. ( 2017 ) . Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation . J Exp Med vol. 214 , ( 6 ) 1787 - 1808 .
Ogbe A, Miao T, Symonds ALJ, Omodho B, Singh R, Bhullar P, Li S, Wang P ( 2015 ) . Early Growth Response Genes 2 and 3 Regulate the Expression of Bcl6 and Differentiation of T Follicular Helper Cells* . Journal of Biological Chemistry vol. 290 , ( 33 ) 20455 - 20465 .
Li S, Symonds ALJ, Miao T, Sanderson I, Wang P ( 2014 ) . Modulation of Antigen-Specific T-Cells as Immune Therapy for Chronic Infectious Diseases and Cancer . Frontiers in Immunology vol. 5 ,
Miao T, Raymond M, Bhullar P, Ghaffari E, Symonds ALJ, Meier UC, Giovannoni G, Li S et al. ( 2013 ) . Early growth response gene-2 controls IL-17 expression and Th17 differentiation by negatively regulating Batf . J Immunol vol. 190 , ( 1 ) 58 - 65 .
Wang P, Miao T, Symonds A, Li S ( 2013 ) . Early growth response genes-2 and-3 are required for naive T cell activation and primary response against virus infection . JOURNAL OF IMMUNOLOGY . vol. 190 ,
Li S, Miao T, Sebastian M, Bhullar P, Ghaffari E, Liu M, Symonds ALJ, Wang P ( 2012 ) . The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells . Immunity vol. 37 , ( 4 ) 685 - 696 .
Liu M, Miao T, Zhu H, Symonds ALJ, Li L, Schurich A, Maini MK, Zhang J et al. ( 2012 ) . IL-2-Engineered nano-APC Effectively Activates Viral Antigen-Mediated T Cell Responses from Chronic Hepatitis B Virus-Infected Patients . JOURNAL OF IMMUNOLOGY vol. 188 , ( 3 ) 1534 - 1543 .
Li SL, Symonds ALJ, Zhu B, Liu MY, Raymond MV, Miao TZ, Wang P ( 2011 ) . Early Growth Response Gene-2 (Egr-2) Regulates the Development of B and T Cells . PLOS ONE vol. 6 , ( 4 ) Article e18498 ,
Liu M, Miao T, Li S-L, Wang P ( 2011 ) . Nano-antigen presenting cells for the development of therapeutic vaccines (53.2) . The Journal of Immunology . vol. 186 , 53.2 - 53.2 .
Li S, Symonds ALJ, Zhu B, Liu M, Raymond MV, Miao T, Wang P ( 2011 ) . Early Growth Response Gene-2 regulates the development of B and T cells . JOURNAL OF IMMUNOLOGY vol. 186 ,
Miao T, Wang P ( 2011 ) . Egr-2 is a tumour repressive gene . JOURNAL OF IMMUNOLOGY vol. 186 ,
Miao T, Wu D, Wheeler A, Wang P, Zhang Y, Bo X, Yeh JS, Subang MC et al. ( 2010 ) . Two cytokine signaling molecules co-operate to promote axonal transport and growth . Experimental Neurology vol. 228 , ( 2 ) 165 - 172 .
Richardson PM, Miao TZ, Wu DS, Zhang Y, Yeh J, Bo XN ( 2009 ) . RESPONSES OF THE NERVE CELL BODY TO AXOTOMY . NEUROSURGERY vol. 65 , ( 4 ) A74 - A79 .
Richardson PM, Miao T, Wu D, Zhang Y, Yeh J, Bo X ( 2009 ) . Responses of the Nerve Cell Body to Axotomy . Neurosurgery vol. 65 , ( suppl_4 ) A74 - A79 .
Miao TZ, Wu DS, Zhang Y, Bo XN, Xiao F, Zhang XY, Magoulas C, Subang MC et al. ( 2008 ) . SOCS3 suppresses AP-1 transcriptional activity in neuroblastoma cells through inhibition of c-Jun N-terminal kinase . MOL CELL NEUROSCI vol. 37 , ( 2 ) 367 - 375 .
Wu DS, Zhang Y, Bo XN, Huang WL, Xiao F, Zhang XY, Miao TZ, Magoulas C et al. ( 2007 ) . Actions of neuropoietic cytokines and cyclic AMP in regenerative conditioning of rat primary sensory neurons . EXP NEUROL vol. 204 , ( 1 ) 66 - 76 .
Richardson PM, Wang P, BO X, Zhang Y, Wu DS, Miao T, Subang M ( 2006 ) . Suppressor of cytokine signaling-3 suppresses the ability of activated signal transducer and activator of transcription-3 to stimulate neurite growth in rat primary sensory neurons . Journal of Neuroscience vol. 26 , 9512 - 9519 .
Li L, Kruidenier L, Miao TZ, Sanderson AR, Wang P ( 2004 ) . SOCS-6 overexpression increases mucosal T cell proliferation and enhances sensitivity to DSS colitis . GASTROENTEROLOGY . vol. 126 , A563 - A563 .