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Research

Publications: Prof Yongjie Lu

Campbell PJ, Getz G, Korbel JO, Stuart JM, Jennings JL, Stein LD, Perry MD, Nahal-Bose HK et al. ( 2020 ) . Pan-cancer analysis of whole genomes . Nature vol. 578 , ( 7793 ) 82 - 93 .
Xu L, Mao X, Grey A, Scandura G, Guo T, Burke E, Marzec J, Abdu S et al. ( 2020 ) . Reply by Authors . The Journal of urology vol. 203 , ( 1 ) 81 - 82 .
Law PJ, Timofeeva M, Fernandez-Rozadilla C, Broderick P, Studd J, Fernandez-Tajes J, Farrington S, Svinti V et al. ( 2019 ) . Association analyses identify 31 new risk loci for colorectal cancer susceptibility . Nature Communications vol. 10 , ( 1 )
Vijayakrishnan J, Studd J, Broderick P, Kinnersley B, Holroyd A, Law PJ, Kumar R, Allan JM et al. ( 2019 ) . Erratum to: Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia (Nature Communications, (2018), 9, 1, (1340), 10.1038/s41467-018-03178-z) . Nature Communications vol. 10 , ( 1 )
Sud A, Thomsen H, Law PJ, Försti A, da Silva Filho MI, Holroyd A, Broderick P, Orlando G et al. ( 2019 ) . Erratum to: Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility (Nature Communications, (2017), 8, 1, (1892), 10.1038/s41467-017-00320-1) . Nature Communications vol. 10 , ( 1 )
Matejcic M, Saunders EJ, Dadaev T, Brook MN, Wang K, Sheng X, Olama AAA, Schumacher FR et al. ( 2019 ) . Erratum to: Germline variation at 8q24 and prostate cancer risk in men of European ancestry (Nature Communications, (2018), 9, 1, (4616), 10.1038/s41467-018-06863-1) . Nature Communications vol. 10 , ( 1 )
Went M, Sud A, Försti A, Halvarsson BM, Weinhold N, Kimber S, van Duin M, Thorleifsson G et al. ( 2019 ) . Erratum to: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma (Nature Communications, (2018), 9, 1, (3707), 10.1038/s41467-018-04989-w) . Nature Communications vol. 10 , ( 1 )
Mancuso N, Gayther S, Gusev A, Zheng W, Penney KL, Henderson BE, Benlloch S, Schumacher FR et al. ( 2019 ) . Erratum to: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions (Nature Communications, (2018), 9, 1, (4079), 10.1038/s41467-018-06302-1) . Nature Communications vol. 10 , ( 1 )
Song D, Powles T, Shi L, Zhang L, Ingersoll MA, Lu YJ ( 2019 ) . Bladder cancer, a unique model to understand cancer immunity and develop immunotherapy approaches . Journal of Pathology vol. 249 , ( 2 ) 151 - 165 .
Stankiewicz E, Guo T, Mao X, Lu YJ ( 2019 ) . Fluorescence in situ hybridization and rehybridization using bacterial artificial chromosome probes . Methods in Molecular Biology vol. 2054 , 243 - 261 .
Guo T, Stankiewicz E, Mao X, Lu YJ ( 2019 ) . The isolation and analysis of circulating tumor cells . Methods in Molecular Biology vol. 2054 , 115 - 128 .
Xu L, Mao X, Grey A, Scandura G, Guo T, Burke E, Marzec J, Abdu S et al. ( 2019 ) . Noninvasive Detection of Clinically Significant Prostate Cancer Using Circulating Tumor Cells . The Journal of Urology vol. 203 , 101097JU000000000000 - 101097JU000000000000 .
Guo T, Wang Y, Mao X, Xu L, Marzec J, Burke E, Scandura G, Stankiewicz E et al. ( 2019 ) . Abstract 2580: Investigation of plasma exosomal miRNA as a biomarker and its potential function in prostate cancer castration resistant development . 2580 - 2580 .
Wu L, Wang J, Cai Q, Cavazos TB, Emami NC, Long J, Shu X-O, Lu Y et al. ( 2019 ) . Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants . Cancer Res vol. 79 , ( 13 ) 3192 - 3204 .
Loveday C, Sud A, Litchfield K, Levy M, Holroyd A, Broderick P, Kote-Jarai Z, Dunning AM et al. ( 2019 ) . Runs of homozygosity and testicular cancer risk . Andrology vol. 7 , ( 4 ) 555 - 564 .
Xue X, Shi F, Dong L, Rong L, Li L, Zheng B, Liu X, Liu W et al. ( 2019 ) . Predisposition of Adrenocortical Carcinoma by Loss of Function of Mismatch Repair Genes and The Role of TP53 In Cancer Development . LABORATORY INVESTIGATION . vol. 99 ,
Schumacher FR, Olama AAA, Berndt SI, Benlloch S, Ahmed M, Saunders EJ, Dadaev T, Leongamornlert D et al. ( 2019 ) . Correction to: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (Nature Genetics, (2018), 50, 7, (928-936), 10.1038/s41588-018-0142-8) . Nature Genetics vol. 51 , ( 2 )
Adams CD, Richmond R, Santos Ferreira DL, Spiller W, Tan V, Zheng J, Würtz P, Donovan J et al. ( 2019 ) . Circulating metabolic biomarkers of screen-detected prostate cancer in the ProtecT study . Cancer Epidemiology Biomarkers and Prevention vol. 28 , ( 1 ) 208 - 216 .
Yeste-Velasco M, Guo T, Mao X, Stankiewicz E, Scandura G, Li H, Wang CS, Kudahetti S et al. ( 2019 ) . The potential of brentuximab vedotin, alone or in combination with current clinical therapies, in the treatment of testicular germ cell tumors . Am J Cancer Res vol. 9 , ( 5 ) 855 - 871 .
Lin HY, Huang PY, Chen DT, Tung HY, Sellers TA, Pow-Sang JM, Eeles R, Easton D et al. ( 2018 ) . AA9int: SNP interaction pattern search using non-hierarchical additive model set . Bioinformatics (Oxford, England) vol. 34 , ( 24 ) 4141 - 4150 .
Dadaev T, Saunders EJ, Newcombe PJ, Anokian E, Leongamornlert DA, Brook MN, Cieza-Borrella C, Mijuskovic M et al. ( 2018 ) . Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants . Nature Communications vol. 9 , ( 1 )
Vijayakrishnan J, Studd J, Broderick P, Kinnersley B, Holroyd A, Law PJ, Kumar R, Allan JM et al. ( 2018 ) . Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia . Nature Communications vol. 9 , ( 1 )
Matejcic M, Saunders EJ, Dadaev T, Brook MN, Wang K, Sheng X, Olama AAA, Schumacher FR et al. ( 2018 ) . Germline variation at 8q24 and prostate cancer risk in men of European ancestry . Nature Communications vol. 9 , ( 1 )
Mancuso N, Gayther S, Gusev A, Zheng W, Penney KL, Kote-Jarai Z, Eeles R, Freedman M et al. ( 2018 ) . Large-scale transcriptome-wide association study identifies new prostate cancer risk regions . Nature Communications vol. 9 , ( 1 )
Guo T, Wang Y, Mao X, Xu L, Marzec J, Burke E, Shaw G, Hines J et al. ( 2018 ) . Investigation of exosomal miRNA as biomarker for prostate cancer castration resistance development . BRITISH JOURNAL OF CANCER . Conference: NCRI Cancer Conferences vol. 119 , 32 - 32 .
Adimonye A, Stankiewicz E, Touche SL, Kudahetti S, Tinwell B, Corbishley C, Lu Y-J, Watkin N et al. ( 2018 ) . The Prognostic Value of PIK3CA Copy Number Gain in Penile Cancer . Urology
Matejcic M, Saunders EJ, Dadaev T, Brook M, Olama AAA, Schumacher FR, Berndt SI, Benlloch S et al. ( 2018 ) . Abstract 227: Germline variation at 8q24 and prostate cancer risk in men of European ancestry . 227 - 227 .
Schumacher FR, Al Olama AA, Berndt SI, Benlloch S, Ahmed M, Saunders EJ, Dadaev T, Leongamornlert D et al. ( 2018 ) . Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci . Nature Genetics vol. 50 , ( 7 ) 928 - 936 .
Adimonye A, Stankiewicz E, La-Touche S, Kudahetti S, Trevisan G, Tinwell B, Corbishley C, Lu Y-J et al. ( 2018 ) . PIK3CA copy number aberration and activation of the PI3K-AKT-mTOR pathway in varied disease states of penile cancer . PLoS ONE vol. 13 , ( 6 ) e0198905 - e0198905 .
Wedge DC, Gundem G, Mitchell T, Woodcock DJ, Martincorena I, Ghori M, Zamora J, Butler A et al. ( 2018 ) . Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets . Nature Genetics vol. 50 , ( 5 ) 682 - 692 .
Adimonye A, Stankiewicz E, Kudahetti S, Trevisan G, Tinwell B, Corbishley C, Lu YJ, Watkin N et al. ( 2018 ) . Analysis of the PI3K-AKT-mTOR pathway in penile cancer: Evaluation of a therapeutically targetable pathway . Oncotarget vol. 9 , ( 22 ) 16074 - 16086 .
Aguirre-Hernández C, Maya-Pineda H, Millán JS, Man YKS, Lu YJ, Halldén G ( 2018 ) . Sensitisation to mitoxantrone-induced apoptosis by the oncolytic adenovirus AdΔΔ through Bcl-2-dependent attenuation of autophagy . Oncogenesis vol. 7 , ( 1 )
Xu L, Bastus NC, Lu YJ ( 2018 ) . Sequencing a single circulating tumor cell for genomic assessment . Oncogenomics: From Basic Research to Precision Medicine ,
Sud A, Thomsen H, Law PJ, Försti A, Filho MIDS, Holroyd A, Broderick P, Orlando G et al. ( 2017 ) . Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility . Nature Communications vol. 8 , ( 1 )
Aguirre-Hernandez C, Maya-Pineda H, Millan JS, Man YKS, Lu YJ, Hallden G ( 2017 ) . Sensitisation to mitoxantrone-induced apoptosis by the oncolytic adenovirus Ad Delta Delta through Bcl-2-dependent attenuation of autophagy . HUMAN GENE THERAPY . Conference: * vol. 28 , A26 - A26 .
Camacho N, Van Loo P, Edwards S, Kay JD, Matthews L, Haase K, Clark J, Dennis N et al. ( 2017 ) . Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data . PLoS Genet vol. 13 , ( 9 ) e1007001 - e1007001 .
Stankiewicz E, Xueying M, Mangham DC, Xu L, Yeste-Velasco M, Fisher G, North B, Chaplin T et al. ( 2017 ) . Identification of FBXL4 as a Metastasis Associated Gene in Prostate Cancer . Scientific Reports Article 5124 ,
Xu L, Mao X, Guo T, Chan PY, Shaw G, Hines J, Stankiewicz E, Wang Y et al. ( 2017 ) . The novel association of circulating tumor cells and circulating megakaryocytes with prostate cancer prognosis . Clin Cancer Res
Berney DM, Lu YJ, Shamash J, Idrees M ( 2017 ) . Postchemotherapy changes in testicular germ cell tumours: biology and morphology . Histopathology vol. 70 , ( 1 ) 26 - 39 .
Lin HY, Chen DT, Huang PY, Liu YH, Ochoa A, Zabaleta J, Mercante DE, Fang Z et al. ( 2017 ) . SNP interaction pattern identifier (SIPI): An intensive search for SNP-SNP interaction patterns . Bioinformatics vol. 33 , ( 6 ) 822 - 833 .
Behjati S, Gundem G, Wedge DC, Roberts ND, Tarpey PS, Cooke SL, Van Loo P, Alexandrov LB et al. ( 2016 ) . Mutational signatures of ionizing radiation in second malignancies . Nature Communications vol. 7 , Article 12605 , 1 - 8 .
Jiang H, Mao X, Huang X, Zhao J, Wang L, Xu J, Zhang H, Lu Y et al. ( 2016 ) . TMPRSS2:ERG fusion gene occurs less frequently in Chinese patients with prostate cancer . Tumor Biology vol. 37 , ( 9 ) 12397 - 12402 .
Mao X, Luo F, Boyd LK, Zhou B, Zhang Y, Stankiewicz E, Marzec J, Vasiljevic N et al. ( 2016 ) . NKAIN2 functions as a novel tumor suppressor in prostate cancer . Oncotarget
Jiang H, Mao X, Huang X, Zhao J, Wang L, Xu J, Zhang H, Lu Y et al. ( 2016 ) . Erratum to: TMPRSS2:ERG fusion gene occurs less frequently in Chinese patients with prostate cancer . Tumour Biol vol. 37 , ( 10 ) 14331 - 14331 .
Stankiewicz E, Mao X, Mangham DC, Xu L, Fisher G, North B, Moller H, Scardino P et al. ( 2016 ) . Identification of FBXL4 as a bone metastasis-associated gene in prostate cancer . Scientific Reports vol. 7 ,
Marzec J, Mao X, Li M, Wang M, Feng N, Gou X, Wang G, Sun Z et al. ( 2016 ) . A genetic study and meta-analysis of the genetic predisposition of prostate cancer in a Chinese population . Oncotarget vol. 7 , ( 16 ) 21393 - 21403 .
Xu L, Mao X, Chan PY, Shamash J, Lu Y-J ( 2016 ) . Analysis of prostate cancer circulating tumour cells isolated with a novel size-based system . The Lancet . vol. 387 ,
Wang Y, Shao N, Mao X, Zhu M, Fan W, Shen Z, Xiao R, Wang C et al. ( 2016 ) . MiR-4638-5p inhibits castration resistance of prostate cancer through repressing kidins220 expression and PI3K/AKT pathway activity . Oncotarget vol. 7 , ( 30 ) 47444 - 47464 .
Imrali A, Mao X, Yeste-Velasco M, Shamash J, Lu Y ( 2016 ) . Rapamycin inhibits prostate cancer cell growth through cyclin D1 and enhances the cytotoxic efficacy of cisplatin . American Journal of Cancer Research vol. 6 , ( 8 ) 1772 - 1784 .
Zhao SC, Zhou BW, Luo F, Mao X, Lu YJ ( 2015 ) . The structure and function of NKAIN2-a candidate tumor suppressor . International Journal of Clinical and Experimental Medicine vol. 8 , ( 10 ) 17072 - 17079 .
Zhang Y, Mao XY, Liu X, Song RR, Berney D, Lu YJ, Ren G ( 2015 ) . High frequency of the SDK1:AMACR fusion transcript in Chinese prostate cancer . International Journal of Clinical and Experimental Medicine vol. 8 , ( 9 ) 15127 - 15136 .
Xu L, Mao X, Imrali A, Syed F, Mutsvangwa K, Berney D, Cathcart P, Hines J et al. ( 2015 ) . Optimization and evaluation of a novel size based circulating tumor cell isolation system . PLoS ONE vol. 10 , ( 9 )
Yeste-Velasco M, Linder ME, Lu YJ ( 2015 ) . Protein S-palmitoylation and cancer . Biochimica et Biophysica Acta - Reviews on Cancer vol. 1856 , ( 1 ) 107 - 120 .
Al Olama AA, Benlloch S, Antoniou AC, Giles G, Severi G, Neal DE, Hamdy FC, Donovan JL et al. ( 2015 ) . Risk analysis of prostate cancer in practical, a multinational consortium, using 25 known prostate cancer susceptibility loci . Cancer Epidemiology Biomarkers and Prevention vol. 24 , ( 7 ) 1121 - 1129 .
Coll-Bastus N, Mao X, Young BD, Sheer D, Lu Y-J ( 2015 ) . DNA replication-dependent induction of gene proximity by androgen . Hum Mol Genet vol. 24 , ( 4 ) 963 - 971 .
Bao JM, He MY, Liu YW, Lu YJ, Hong YQ, Luo HH, Ren ZL, Zhao SC et al. ( 2015 ) . AGE/RAGE/Akt pathway contributes to prostate cancer cell proliferation by promoting Rb phosphorylation and degradation . American Journal of Cancer Research vol. 5 , ( 5 ) 1741 - 1750 .
Lian WQ, Luo F, Song XL, Lu YJ, Zhao SC ( 2015 ) . Gonorrhea and prostate cancer incidence: An updated meta-analysis of 21 epidemiologic studies . Medical Science Monitor vol. 21 , 1895 - 1903 .
Ren G, Zhang Y, Mao X, Liu X, Mercer E, Marzec J, Ding D, Jiao Y et al. ( 2014 ) . Transcription-mediated chimeric RNAs in prostate cancer: time to revisit old hypothesis? . OMICS vol. 18 , ( 10 ) 615 - 624 .
Mercer EJ, Imrali A, Sharpe K, Hallden G, Lu Y-J ( 2014 ) . Abstract 713: Utilizing a potent and selective nonreplicating adenoviral mutant (Ad5-TV-CU), with gene expression controlled by androgen receptor-dependent activation domains in the TMPRSS2 gene, as a novel prodrug-converting enzyme therapy for prostate cancer . 713 - 713 .
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljevi¿ N, Chaplin T et al. ( 2014 ) . Identification of ZDHHC14 as a novel human tumour suppressor gene . J Pathol vol. 232 , ( 5 ) 566 - 577 .
Allen MD, Luong P, Hudson C, Leyton J, Delage B, Ghazaly E, Cutts R, Yuan M et al. ( 2014 ) . Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging . Cancer Res vol. 74 , ( 3 ) 896 - 907 .
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T et al. ( 2014 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . Cell Death Dis vol. 5 ,
Zhang H, Fan Y, Ge N, Wang X, Sun W, Mao R, Bu W, Creighton CJ et al. ( 2014 ) . Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells . Journal of Pathology vol. 232 , ( 1 ) 75 - 86 .
Zhao C-B, Bao J-M, Lu Y-J, Zhao T, Zhou X-H, Zheng D-Y, Zhao S-C ( 2014 ) . Co-expression of RAGE and HMGB1 is associated with cancer progression and poor patient outcome of prostate cancer . Am J Cancer Res vol. 4 , ( 4 ) 369 - 377 .
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljevíc N, Chaplin T et al. ( 2014 ) . Erratum:Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol (2014); 232: 566-577)) . Journal of Pathology vol. 234 , ( 1 )
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh MT et al. ( 2014 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . Cell death & disease . vol. 5 ,
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Marzec J, Vasiljevic N, Chaplin T, Foster JM et al. ( 2014 ) . Identification of ZDHHC14 as a novel human tumour suppressor: gene . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S90 - S90 .
Mao X, Li J, Xu X, Boyd LK, He W, Stankiewicz E, Kudahetti SC, Cao G et al. ( 2014 ) . Involvement of different mechanisms for the association of CAG repeat length polymorphism in androgen receptor gene with prostate cancer . Am J Cancer Res vol. 4 , ( 6 ) 886 - 896 .
Bastus NC, Mao X, Young BD, Sheer D, Lu Y-J ( 2014 ) . Novel function of androgen receptor-the regulation of DNA replication and genomic movement . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S89 - S89 .
Mao X, Marzec J, Li M, Zhang Z, Feng N, Gou X, Sun Z, Xu J et al. ( 2014 ) . Population differences in the genetic risk of prostate cancer and predisposition loci in the Chinese population . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S89 - S89 .
Xu L, Irrami A, Shamash J, Lu Y-J ( 2014 ) . Size-based isolation of circulating tumour cells and its application in advanced prostate cancer . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S89 - S89 .
Sharpe K, Stewart GD, Mackay A, Van Neste C, Rofe C, Berney D, Kayani I, Bex A et al. ( 2013 ) . The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer . Clin Cancer Res vol. 19 , ( 24 ) 6924 - 6934 .
Vasiljevi¿ N, Ahmad AS, Beesley C, Thorat MA, Fisher G, Berney DM, Møller H, Yu Y et al. ( 2013 ) . Association between DNA methylation of HSPB1 and death in low Gleason score prostate cancer . Prostate Cancer Prostatic Dis vol. 16 , ( 1 ) 35 - 40 .
Al Olama AA, Kote-Jarai Z, Schumacher FR, Wiklund F, Berndt SI, Benlloch S, Giles GG, Severi G et al. ( 2013 ) . A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease . HUMAN MOLECULAR GENETICS vol. 22 , ( 2 ) 408 - 415 .
Li J, Mercer E, Gou X, Lu Y-J ( 2013 ) . Ethnical disparities of prostate cancer predisposition: genetic polymorphisms in androgen-related genes . Am J Cancer Res vol. 3 , ( 2 ) 127 - 151 .
Ren G, Liu X, Mao X, Zhang Y, Stankiewicz E, Hylands L, Song R, Berney DM et al. ( 2012 ) . Identification of frequent BRAF copy number gain and alterations of RAF genes in chinese prostate cancer . Genes Chromosomes and Cancer vol. 51 , ( 11 ) 1014 - 1023 .
Boyd LK, Mao X, Lu Y-J ( 2012 ) . The complexity of prostate cancer: genomic alterations and heterogeneity . Nat Rev Urol vol. 9 , ( 11 ) 652 - 664 .
Boyd LK, Mao X, Xue L, Lin D, Chaplin T, Kudahetti SC, Stankiewicz E, Yu Y et al. ( 2012 ) . High-resolution genome-wide copy-number analysis suggests a monoclonal origin of multifocal prostate cancer . Genes Chromosomes Cancer vol. 51 , ( 6 ) 579 - 589 .
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Chaplin T, Xue L, Xu M et al. ( 2012 ) . Abstract 4858: Identification of ZDHHC14 as a novel tumor suppressor gene commonly downregulated in human cancers . 4858 - 4858 .
Mao X, Coll Bastus N, Boyd L, Yu Y, Ren G, Beltran L, Oliver R, Young BD et al. ( 2012 ) . The different genetic alterations between Western and Chinese prostate cancers and the underlying mechanisms . J Clin Oncol vol. 30 , ( 5_suppl )
Lu Y-J, Liu X, Mao X, Hylands L, Clark J, Cooper C, Ren G ( 2012 ) . Truncation of BRAF and Raf1 in prostate cancer in China . JOURNAL OF CLINICAL ONCOLOGY vol. 30 , ( 5 )
Lu YJ, Liu X, Mao X, Hylands L, Clark J, Cooper C, Ren G ( 2012 ) . Truncation of BRAF and Raf1 in prostate cancer in China . J Clin Oncol vol. 30 , ( 5_suppl )
Xue L, Mao X, Ren G, Stankiewicz E, Kudahetti SC, Lin D, Beltran L, Berney DM et al. ( 2012 ) . Chinese and Western prostate cancers show alternate pathogenetic pathways in association with ERG status . Am J Cancer Res vol. 2 , ( 6 ) 736 - 744 .
Ren G, Liu X, Mao X, Zhang Y, Stankiewicz E, Hylands L, Song R, Berney DM et al. ( 2012 ) . Identification of frequent BRAF copy number gain and alterations of RAF genes in chinese prostate cancer . Genes Chromosomes and Cancer
Kote-Jarai Z, Al Olama AA, Giles GG, Severi G, Schleutker J, Weischer M, Campa D, Riboli E et al. ( 2011 ) . Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study . NAT GENET vol. 43 , ( 8 ) 785 - U96 .
Lu YJ, Mao X, Yu Y, Boyd LK, Oliver RTD, Berney DM ( 2011 ) . Distinct genomic differences in prostate cancer between western countries and china . BRITISH JOURNAL OF SURGERY . vol. 98 , E3 - E3 .
Bastus NC, Lu Y-J, Boyd LK, Mao X, Stankiewicz E, Kudahetti SC, Oliver TD, Berney DM ( 2011 ) . Abstract 3048: Enhanced androgen signalling pathway increases the risk of prostate cancer through induction of TMPRSS2:ERG fusion . 3048 - 3048 .
Lu Y-J, Mao X, Xue L, Boyd LK, Kudahetti SC, Yu Y, Ren G, Lin D et al. ( 2011 ) . Abstract 3878: The different genetic alterations between Western and Chinese samples indicate alternate pathways of prostate cancer development . 3878 - 3878 .
Boyd LK, Xue L, Mao X, Lin D, Chaplin T, Kudahetti SC, Stankiewicz E, Bisson I et al. ( 2011 ) . Abstract 4831: Monoclonal origin of multifocal cancer and the step-wise genetic events of prostate carcinogenesis . 4831 - 4831 .
Allen M, Syed N, Luong F, Howarth K, Gorman P, Tomlinson I, Roylance R, Lu Y-J et al. ( 2011 ) . Abstract 76: Epigenetic silencing of argininosuccinate synthetase renders human bladder cancer cells sensitive to pegylated arginine deiminase . 76 - 76 .
Stankiewicz E, Prowse DM, Ng M, Cuzick J, Mesher D, Hiscock F, Lu Y-J, Watkin N et al. ( 2011 ) . Alternative HER/PTEN/Akt pathway activation in HPV positive and negative penile carcinomas . PLoS One vol. 6 , ( 3 )
Stankiewicz E, Mesher D, Ng M, Cuzick J, Prowse D, Hiscock F, Lu YJ, Lam W et al. ( 2011 ) . Alternative Pathways of Akt Pathway Activation in HPV Positive and Negative Penile Carcinomas . MODERN PATHOLOGY . vol. 24 , 225A - 226A .
Vasiljevi¿ N, Wu K, Brentnall AR, Kim DC, Thorat MA, Kudahetti SC, Mao X, Xue L et al. ( 2011 ) . Absolute quantitation of DNA methylation of 28 candidate genes in prostate cancer using pyrosequencing . Dis Markers vol. 30 , ( 4 ) 151 - 161 .
Mao X, Boyd LK, Yáñez-Muñoz RJ, Chaplin T, Xue L, Lin D, Shan L, Berney DM et al. ( 2011 ) . Chromosome rearrangement associated inactivation of tumour suppressor genes in prostate cancer . Am J Cancer Res vol. 1 , ( 5 ) 604 - 617 .
Bastus NC, Boyd LK, Mao X, Stankiewicz E, Kudahetti SC, Oliver RTD, Berney DM, Lu Y-J ( 2010 ) . Androgen-induced TMPRSS2:ERG fusion in nonmalignant prostate epithelial cells . Cancer Res vol. 70 , ( 23 ) 9544 - 9548 .
Mao X, Yu Y, Boyd LK, Ren G, Lin D, Chaplin T, Kudahetti SC, Stankiewicz E et al. ( 2010 ) . Distinct genomic alterations in prostate cancers in Chinese and Western populations suggest alternative pathways of prostate carcinogenesis . Cancer Res vol. 70 , ( 13 ) 5207 - 5212 .
Noel EE, Yeste-Velasco M, Mao X, Perry J, Kudahetti SC, Li NF, Sharp S, Chaplin T et al. ( 2010 ) . The association of CCND1 overexpression and cisplatin resistance in testicular germ cell tumors and other cancers . Am J Pathol vol. 176 , ( 6 ) 2607 - 2615 .
Shan L, Ambroisine L, Clark J, Yáñez-Muñoz RJ, Fisher G, Kudahetti SC, Yang J, Kia S et al. ( 2010 ) . The identification of chromosomal translocation, t(4;6)(q22;q15), in prostate cancer . Prostate Cancer Prostatic Dis vol. 13 , ( 2 ) 117 - 125 .
Pantazi E, Trigiante G, Warnes G, Gemenetzidis E, Teh MT, Ikram M, Shan L, Lu YJ et al. ( 2010 ) . Overexpression of GLI2 in human keratinocytes results in resistance to ultraviolet B-induced apoptosis and increased chromosomal instability . BRITISH JOURNAL OF DERMATOLOGY . vol. 162 , 948 - 948 .
Eeles RA, Kote-Jarai Z, Al Olama AA, Giles GG, Guy M, Severi G, Muir K, Hopper JL et al. ( 2009 ) . Identification of seven new prostate cancer susceptibility loci through a genome-wide association study . NAT GENET vol. 41 , ( 10 ) 1116 - U97 .
Shan L, Ambroisine L, Clark J, Yanez-Munoz R, Fisher G, Kudahetti S, Foster C, Reuter V et al. ( 2009 ) . POD-04.07: A New Recurrent Chromosomal Translocation, T(4;6)(q22;q15), in Prostate Cancer . Urology vol. 74 , ( 4 )
Perry J, Powles T, Shamash J, Veerupillai A, McGrowder E, Noel E, Lu Y-J, Oliver T et al. ( 2009 ) . The relative activity of cisplatin, oxaliplatin and satraplatin in testicular germ cell tumour sensitive and resistant cell lines . Cancer Chemother Pharmacol vol. 64 , ( 5 ) 925 - 933 .
Cai X, Xiao T, James SY, Da J, Lin D, Liu Y, Zheng Y, Zou S et al. ( 2009 ) . Metastatic potential of lung squamous cell carcinoma associated with HSPC300 through its interaction with WAVE2 . Lung Cancer vol. 65 , ( 3 ) 299 - 305 .
Boyd LK, Mao X, Lu YJ ( 2009 ) . Use of SNPs in cancer predisposition analysis, diagnosis and prognosis: Tools and prospects . Expert Opinion on Medical Diagnostics vol. 3 , ( 3 ) 313 - 326 .
Mao X, Young BD, Chaplin T, Shipley J, Lu Y-J ( 2008 ) . Subtle genomic alterations and genomic instability revealed in diploid cancer cell lines . Cancer Lett vol. 267 , ( 1 ) 49 - 54 .
Noel EE, Perry J, Chaplin T, Mao X, Cazier J-B, Joel SP, Oliver RTD, Young BD et al. ( 2008 ) . Identification of genomic changes associated with cisplatin resistance in testicular germ cell tumor cell lines . Genes Chromosomes Cancer vol. 47 , ( 7 ) 604 - 613 .
Mao X, Shaw G, James SY, Purkis P, Kudahetti SC, Tsigani T, Kia S, Young BD et al. ( 2008 ) . Detection of TMPRSS2:ERG fusion gene in circulating prostate cancer cells . Asian J Androl vol. 10 , ( 3 ) 467 - 473 .
Lane T, Hines J, Strefford J, Lu YJ, Yanez-Munoz R, Oliver T ( 2008 ) . The t(4;6) chromosomal translocation is a recurrent event in prostate cancer . EUR UROL SUPPL vol. 7 , ( 3 ) 272 - 272 .
Noel EE, Ragavan N, Walsh MJ, James SY, Matanhelia SS, Nicholson CM, Lu Y-J, Martin FL ( 2008 ) . Differential gene expression in the peripheral zone compared to the transition zone of the human prostate gland . Prostate Cancer Prostatic Dis vol. 11 , ( 2 ) 173 - 180 .
McIntyre A, Summersgill B, Lu YJ, Missiaglia E, Kitazawa S, Oosterhuis JW, Looijenga LH, Shipley J ( 2007 ) . Genomic copy number and expression patterns in testicular germ cell tumours . BRIT J CANCER vol. 97 , ( 12 ) 1707 - 1712 .
Li NF, Broad S, Lu YJ, Yang JS, Watson R, Hagemann T, Wilbanks G, Jacobs I et al. ( 2007 ) . Human ovarian surface epithelial cells immortalized with hTERT maintain functional pRb and p53 expression . Cell Prolif vol. 40 , ( 5 ) 780 - 794 .
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