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Research

Publications: Dr Cecilia Sze-Lai Lai

Lewis A, Felice C, Kumagai T, Lai C, Singh K, Jeffery RR, Feakins R, Giannoulatou E et al. ( 2017 ) . The miR-200 family is increased in dysplastic lesions in ulcerative colitis patients . PLoS One vol. 12 , ( 3 ) e0173664 - e0173664 .
Biancheri P, Di Sabatino A, Nijhuis A, Lai C, Ghosh A, Macdonald TT, Lindsay J, Silver A et al. ( 2013 ) . OC.07.1 MICRO-RNA EXPRESSION PROFILING IDENTIFIES MIR-29B AS A RELEVANT PRO-FIBROGENIC FACTOR IN CROHN'S DISEASE INTESTINAL STRICTURES . Digestive and Liver Disease vol. 45 , s70 - s71 .
Ghosh A, Lai C, McDonald S, Suraweera N, Sengupta N, Propper D, Dorudi S, Silver A ( 2013 ) . HSP27 expression in primary colorectal cancers is dependent on mutation of KRAS and PI3K/AKT activation status and is independent of TP53 . Exp Mol Pathol vol. 94 , ( 1 ) 103 - 108 .
Biancheri P, Nijhuis A, Di Sabatino A, Lai C, Ghosh A, MacDonald TT, Corazza GR, Lindsay J et al. ( 2013 ) . P057 Micro-RNA expression profiling identifies miR-29b as a relevant pro-fibrogenic factor in Crohn's disease intestinal strictures . Journal of Crohn's and Colitis vol. 7 , ( Supplement_1 ) s32 - s32 .
Sengupta N, Yau C, Sakthianandeswaren A, Mouradov D, Gibbs P, Suraweera N, Cazier J, Polanco-Echeverry G et al. ( 2013 ) . Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion . Molecular Cancer Article 1 ,
Nijhuis A, Biancheri P, Lai C, Ghosh A, Boitsova T, Chan C, MacDonald T, Lindsay J et al. ( 2012 ) . PMO-229 MicroRNA expression profiling in stricturing Crohn's disease identifies miR-34a as a functionally relevant influence on disease phenotype . Gut vol. 61 , ( Suppl 2 )
Biancheri P, Nijhuis A, Lai C, Ghosh A, Feakins R, Chan C, Di Sabatino A, Corazza GR et al. ( 2012 ) . Tu1915 Differential MicroRNA Expression Profiles in Crohn's Disease Strictured Versus Non-Strictured Intestine . Gastroenterology vol. 142 , ( 5 ) s - 877 .
Lai C, Robinson J, Clark S, Stamp G, Poulsom R, Silver A ( 2011 ) . Elevation of WNT5A expression in polyp formation in Lkb1+/- mice and Peutz-Jeghers syndrome . J Pathol vol. 223 , ( 5 ) 584 - 592 .
Robinson J, Lai C, Martin A, Nye E, Tomlinson I, Silver A ( 2009 ) . Oral rapamycin reduces tumour burden and vascularization in Lkb1(+/-) mice . J Pathol vol. 219 , ( 1 ) 35 - 40 .
Sengupta N, Gill KA, MacFie TS, Lai CS, Suraweera N, Mcdonald S, Silver A ( 2008 ) . Management of colorectal cancer: a role for genetics in prevention and treatment? . Pathol Res Pract vol. 204 , ( 7 ) 469 - 477 .
Patel H, Polanco-Echeverry G, Segditsas S, Volikos E, McCart A, Lai C, Guenther T, Zaitoun A et al. ( 2007 ) . Activation of AKT and nuclear accumulation of wild type TP53 and MDM2 in anal squamous cell carcinoma . Int J Cancer vol. 121 , ( 12 ) 2668 - 2673 .