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Research

Publications: Prof Janet Jones

Brockmoeller S, Young C, Lee J, Arends MJ, Wilkins BS, Thomas GJ, Oien KA, Jones L et al. ( 2019 ) . Survey of UK histopathology consultants' attitudes towards academic and molecular pathology . Journal of Clinical Pathology . vol. 72 , 399 - 405 .
Coulson-Gilmer C, Humphries MP, Sundara Rajan S, Droop A, Jackson S, Condon A, Cserni G, Jordan LB et al. ( 2018 ) . Stanniocalcin 2 expression is associated with a favourable outcome in male breast cancer . J Pathol Clin Res vol. 4 , ( 4 ) 241 - 249 .
Moore DA, Young CA, Morris HT, Oien KA, Lee JL, Jones JL, Salto-Tellez M ( 2018 ) . Time for change: A new training programme for morpho-molecular pathologists? . Journal of Clinical Pathology vol. 71 , ( 4 ) 285 - 290 .
Fearon AE, Carter EP, Clayton NS, Wilkes EH, Baker AM, Kapitonova E, Bakhouche BA, Tanner Y et al. ( 2018 ) . PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer . Cell Reports vol. 22 , ( 9 ) 2469 - 2481 .
Pollard J, Burns PA, Hughes TA, Ho-Yen C, Jones JL, Mukherjee G, Omoniyi-Esan GO, Titloye NA et al. ( 2018 ) . Differential Expression of MicroRNAs in Breast Cancers from Four Different Ethnicities . Pathobiology vol. 85 , ( 4 ) 220 - 226 .
Pearce OMT, Delaine-Smith R, Maniati E, Nichols S, Wang J, Böhm S, Rajeeve V, Ullah D et al. ( 2017 ) . Deconstruction of a metastatic tumor microenvironment reveals a common matrix response in human cancers . Cancer Discov
Saunderson EA, Stepper P, Gomm JJ, Hoa L, Morgan A, Allen MD, Jones JL, Gribben JG et al. ( 2017 ) . Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors . Nature Communications vol. 8 , ( 1 )
Jones JL, Oien KA, Lee JL, Salto-Tellez M ( 2017 ) . Morphomolecular pathology: Setting the framework for a new generation of pathologists . British Journal of Cancer vol. 117 , ( 11 ) 1581 - 1582 .
Nelan RL, Hayward MK, Jones JL ( 2017 ) . The growth of molecular diagnostics: Stratified Medicine Programme, the 100,000 Genomes Project and the future . Diagnostic Histopathology vol. 23 , ( 10 ) 458 - 467 .
Humphries MP, Sundara Rajan S, Droop A, Suleman CAB, Carbone C, Nilsson C, Honarpisheh H, Cserni G et al. ( 2017 ) . A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer . Clin Cancer Res vol. 23 , ( 10 ) 2575 - 2583 .
Carter EP, Gopsill JA, Gomm JJ, Jones JL, Grose RP ( 2017 ) . A 3D in vitro model of the human breast duct: A method to unravel myoepithelial-luminal interactions in the progression of breast cancer . Breast Cancer Research vol. 19 , ( 1 )
Humphries MP, Sundara Rajan S, Honarpisheh H, Cserni G, Dent J, Fulford L, Jordan LB, Jones JL et al. ( 2017 ) . Characterisation of male breast cancer: a descriptive biomarker study from a large patient series . Sci Rep vol. 7 ,
Sarper M, Allen MD, Gomm J, Haywood L, Decock J, Thirkettle S, Ustaoglu A, Sarker SJ et al. ( 2017 ) . Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function . Breast Cancer Research vol. 19 , ( 1 )
Ironside A, Hawkesford K, Gomm J, Haywood L, Goulding I, Wang J, Lamaziere A, Poirot M et al. ( 2017 ) . Molecular mediators of mammographic density . CANCER RESEARCH . Conference: 2016 San Antonio Breast Cancer Symposium from: 06/12/2016 to: 10/12/2016 , vol. 77 ,
Patel H, Abduljabbar R, Lai CF, Periyasamy M, Harrod A, Gemma C, Steel JH, Patel N et al. ( 2016 ) . Expression of CDK7, cyclin H, and MAT1 is elevated in breast cancer and is prognostic in estrogen receptor-positive breast cancer . Clinical Cancer Research vol. 22 , ( 23 ) 5929 - 5938 .
Hayward M, Allen MD, Dreger S, Marshall JF, Jones JL ( 2016 ) . Investigating the Functional Significance of Aberrant alpha v beta 6 and Fibronectin Expression in Myoepithelial Cells: Role in the Progression of DCIS? . JOURNAL OF PATHOLOGY . Conference: Nottingham Pathology 2016 from: 28/06/2016 to: 01/07/2016 , vol. 240 , 28 - 28 .
Jones JL, Gomm J, Haywood L, Morgan A, Goulding I, Allen M, Chelala C, Gadelata E ( 2016 ) . Breast Cancer Now Cell Culture Programme: a bespoke resource for the research community . Breast Cancer Research and Treatment . Conference: UK Breast Cancer Research Symposium 2016 from: 22/07/2016 to: 23/07/2016 , vol. 159 , 196 - 196 .
Morrissey B, Blyth K, Carter P, Chelala C, Jones L, Holen I, Speirs V ( 2016 ) . SEARCHBreast: A new online resource to make surplus material from in vivo models of breast cancer visible and accessible to researchers . Breast Cancer Research vol. 18 , ( 1 )
Ironside AJ, Jones JL ( 2016 ) . Stromal characteristics may hold the key to mammographic density: the evidence to date . Oncotarget vol. 7 , ( 21 ) 31550 - 31562 .
Purrington KS, Visscher DW, Wang C, Yannoukakos D, Hamann U, Nevanlinna H, Cox A, Giles GG et al. ( 2016 ) . Genes associated with histopathologic features of triple negative breast tumors predict molecular subtypes . Breast Cancer Research and Treatment vol. 157 , ( 1 ) 117 - 131 .
Winters ZE, Horsnell J, Schmid P, Jones JL, Shaaban A, Maxwell AJ, Williams N, Esserman L et al. ( 2016 ) . Time for a randomised clinical trial evaluating breast conserving surgery compared to mastectomy in ipsilateral mutlifocal breast cancer (MFBC)? . Breast vol. 26 , 149 - 150 .
Clarke CJ, Berg TJ, Birch J, Ennis D, Mitchell L, Cloix C, Campbell A, Sumpton D et al. ( 2016 ) . The initiator methionine trna drives secretion of type II collagen from stromal fibroblasts to promote tumor growth and angiogenesis . Current Biology vol. 26 , ( 6 ) 755 - 765 .
Eccles DM, Li N, Handwerker R, Maishman T, Copson ER, Durcan LT, Gerty SM, Jones L et al. ( 2016 ) . Genetic testing in a cohort of young patients with HER2-amplified breast cancer . Annals of Oncology vol. 27 , ( 3 ) 467 - 473 .
Downey CL, Simpkins SA, Holliday DL, Jones JL, Jordan LB, Kulka J, Hanby AM, Speirs V ( 2015 ) . Reponse to: comment on, 'Tumour-stroma ratio (TSR) in oestrogen-positive breast cancer patients' . Br J Cancer vol. 112 , ( 11 ) 1833 - 1834 .
Ho-Yen CM, Jones JL, Kermorgant S ( 2015 ) . The clinical and functional significance of c-Met in breast cancer: a review . Breast Cancer Res vol. 17 ,
Millican-Slater R, Good R, Nash C, Heads JA, Pollock S, Chalkley R, Gomm J, Jones JL et al. ( 2015 ) . Adding value to rare tissue samples donated to biobanks: characterisation of breast tissue and primary cell cultures obtained from a female-to-male transgender patient . Cell and Tissue Banking vol. 16 , ( 1 ) 27 - 34 .
Laversin SA, Krishnan J, Schapira A, Dou L, Ashton-Key M, Jones JL, Allen MD, Glennie MJ et al. ( 2014 ) . Manipulation of macrophage Fc gamma receptors to improve antibody immunotherapy of HER2+breast cancer . IMMUNOLOGY vol. 143 , 128 - 129 .
Allen MD, Marshall JF, Jones JL ( 2014 ) . αvβ6 Expression in myoepithelial cells: a novel marker for predicting DCIS progression with therapeutic potential . Cancer Res vol. 74 , ( 21 ) 5942 - 5947 .
Wong P-P, Yeoh CC, Ahmad AS, Chelala C, Gillett C, Speirs V, Jones JL, Hurst HC ( 2014 ) . Identification of MAGEA antigens as causal players in the development of tamoxifen-resistant breast cancer . Oncogene vol. 33 , ( 37 ) 4579 - 4588 .
Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR et al. ( 2014 ) . Therapeutic targeting of integrin αvβ6 in breast cancer . J Natl Cancer Inst vol. 106 , ( 8 )
Elosegui-Artola A, Bazellières E, Allen MD, Andreu I, Oria R, Sunyer R, Gomm JJ, Marshall JF et al. ( 2014 ) . Rigidity sensing and adaptation through regulation of integrin types . Nat Mater vol. 13 , ( 6 ) 631 - 637 .
Downey CL, Simpkins SA, White J, Holliday DL, Jones JL, Jordan LB, Kulka J, Pollock S et al. ( 2014 ) . The prognostic significance of tumour-stroma ratio in oestrogen receptor-positive breast cancer . Br J Cancer vol. 110 , ( 7 ) 1744 - 1747 .
Alexopoulou AN, Ho-Yen CM, Papalazarou V, Elia G, Jones JL, Hodivala-Dilke K ( 2014 ) . Tumour-associated endothelial-FAK correlated with molecular sub-type and prognostic factors in invasive breast cancer . BMC Cancer vol. 14 ,
Speirs V, Chelala C, Coates R, Jones JL, Matharoo-Ball B, Quinlan P ( 2014 ) . The Breast Cancer Campaign Tissue Bank: Generating new biomaterials to accelerate breast cancer research . EUROPEAN JOURNAL OF CANCER . vol. 50 , S200 - S200 .
Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA et al. ( 2014 ) . Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence . Clin Cancer Res vol. 20 , ( 2 ) 344 - 357 .
Endrizzi M, Diemoz PC, Millard TP, Jones JL, Speller RD, Robinson IK, Olivo A ( 2014 ) . Hard X-ray dark-field imaging with incoherent sample illumination . APPLIED PHYSICS LETTERS vol. 104 , ( 2 ) Article ARTN 024106 ,
Moore K, Thomas G, Duffy S, Warwick J, Gabe R, Chou P, Ellis I, Green A et al. ( 2013 ) . Abstract P4-15-01: Integrin avb6 is a therapeutic target for high-risk breast cancer and enhances trastuzumab efficacy .
Ho-Yen CM, Green AR, Rakha EA, Brentnall AR, Ellis IO, Kermorgant S, Jones JL ( 2013 ) . C-Met in invasive breast cancer: is there a relationship with the basal-like subtype? . Cancer vol. 120 , ( 2 ) 163 - 171 .
Pollard JA, Burns PA, Hughes TA, Mukherjee G, Jones JL, Ho-Yen C, Esan GOO, Titloye NA et al. ( 2013 ) . Differential Expression of MicroRNAs in Breast Cancers From Four Different Ethnicities . JOURNAL OF PATHOLOGY . vol. 231 , 24 - 24 .
Olivo A, Gkoumas S, Endrizzi M, Hagen CK, Szafraniec MB, Diemoz PC, Munro PRT, Ignatyev K et al. ( 2013 ) . Low-dose phase contrast mammography with conventional x-ray sources . MEDICAL PHYSICS vol. 40 , ( 9 ) Article ARTN 090701 ,
Abrahamsson SV, Angelini DF, Dubinsky AN, Morel E, Oh U, Jones JL, Carassiti D, Reynolds R et al. ( 2013 ) . Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis . Brain vol. 136 , ( Pt 9 ) 2888 - 2903 .
Gaynor K, Grigorieva I, Allen MD ( 2013 ) . GATA3 Mutations Found in Breast Cancers May Be Associated with Aberrant Nuclear Localization, Reduced Transactivation and Cell Invasiveness . Hormones and Cancer vol. Volume 4 , ( 3 ) 123 - 139 .
Ho-Yen C, Bowen RL, Kermorgant S, Jones JL ( 2013 ) . Comment on 'High MET expression is an adverse prognostic factor in patients with triple-negative breast cancer' . Br J Cancer vol. 108 , ( 10 ) 2195 - 2196 .
Robbez-Masson LJ, Bödör C, Jones JL, Hurst HC, Fitzgibbon J, Hart IR, Grose RP ( 2013 ) . Functional analysis of a breast cancer-associated FGFR2 single nucleotide polymorphism using zinc finger mediated genome editing . PLoS One vol. 8 , ( 11 )
Elosegui-Artola A, Bazellieres E, Allen MD, Andreu I, Marshall JF, Jones JL, Trepat X, Roca-Cusachs P ( 2013 ) . Rigidity sensing and adaptation through regulation of integrin populations . MOLECULAR BIOLOGY OF THE CELL vol. 24 ,
Verma R, Bowen RL, Slater SE, Mihaimeed F, Jones JL ( 2012 ) . Pathological and epidemiological factors associated with advanced stage at diagnosis of breast cancer . Br Med Bull vol. 103 , ( 1 ) 129 - 145 .
Dreger SA, Payne SJ, Dawoud M, Robinson SD, Marshall JF, Hodivala-Dilke KM, Allen MD, Jones JL ( 2012 ) . Up-regulation of alpha v beta 6 integrin and fibronectin EDA in myoepithelial cells contribute to the angiogenic switch in pre-invasive breast cancer . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 93 , A24 - A24 .
Shaaban AM, Ball GR, Brannan RA, Cserni G, Di Benedetto A, Dent J, Fulford L, Honarpisheh H et al. ( 2012 ) . A comparative biomarker study of 514 matched cases of male and female breast cancer reveals gender-specific biological differences . BREAST CANCER RESEARCH AND TREATMENT vol. 133 , ( 3 ) 949 - 958 .
Ahmed KO, Allen M, Gomm J, Marshall J, Jones JL ( 2012 ) . MYOEPITHELIAL CONTROL OF THE INFLAMMATORY MICROENVIRONMENT PROMOTES TRANSITION OF DCIS TO INVASIVE DISEASE . ANNALS OF ONCOLOGY . vol. 23 , 19 - 19 .
Shaw EC, Hanby AM, Wheeler K, Shaaban AM, Poller D, Barton S, Treanor D, Fulford L et al. ( 2012 ) . Observer agreement comparing the use of virtual slides with glass slides in the pathology review component of the POSH breast cancer cohort study . JOURNAL OF CLINICAL PATHOLOGY vol. 65 , ( 5 ) 403 - 408 .
Jones JL ( 2012 ) . Breast Cancer - The Beginning . JOURNAL OF PATHOLOGY . vol. 226 , S2 - S2 .
Hill-Cawthorne GA, Button T, Tuohy O, Jones JL, May K, Somerfield J, Green A, Giovannoni G et al. ( 2012 ) . Long term lymphocyte reconstitution after alemtuzumab treatment of multiple sclerosis . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY vol. 83 , ( 3 ) 298 - 304 .
Sarper M, Allen M, Decock J, Marshall JF, Edwards DR, Jones JL ( 2012 ) . Loss of MMP-8 Expression Contributes to Altered Myoepithelial Cell Function in DCIS . JOURNAL OF PATHOLOGY . vol. 226 , S13 - S13 .
Jones DT, Lechertier T, Mitter R, Herbert JMJ, Bicknell R, Jones JL, Li J-L, Buffa F et al. ( 2012 ) . Gene expression analysis in human breast cancer associated blood vessels . PLoS One vol. 7 , ( 10 )
Evans DG, Howell A, Ward D, Lalloo F, Jones JL, Eccles DM ( 2011 ) . Prevalence of BRCA1 and BRCA2 mutations in triple negative breast cancer . J MED GENET vol. 48 , ( 8 ) 520 - 522 .
Allen MD, Vaziri R, Green M, Chelala C, Brentnall AR, Dreger S, Vallath S, Nitch-Smith H et al. ( 2011 ) . Clinical and functional significance of α9β1 integrin expression in breast cancer: a novel cell-surface marker of the basal phenotype that promotes tumour cell invasion . J Pathol vol. 223 , ( 5 ) 646 - 658 .
Clark SE, Warwick J, Carpenter R, Bowen RL, Duffy SW, Jones JL ( 2011 ) . Molecular subtyping of DCIS: heterogeneity of breast cancer reflected in pre-invasive disease . Br J Cancer vol. 104 , ( 1 ) 120 - 127 .
Mulligan AM, Couch FJ, Barrowdale D, Domchek SM, Eccles D, Nevanlinna H, Ramus SJ, Robson M et al. ( 2011 ) . Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 . BREAST CANCER RESEARCH vol. 13 , ( 6 ) Article ARTN R110 ,
Allen M, Jones JL ( 2011 ) . Jekyll and Hyde: the role of the microenvironment on the progression of cancer . J PATHOL vol. 223 , ( 2 ) 162 - 176 .
Wilson JRF, Bateman AC, Hanson H, An Q, Evans G, Rahman N, Jones JL, Eccles DM ( 2010 ) . A novel HER2-positive breast cancer phenotype arising from germline TP53 mutations . J MED GENET vol. 47 , ( 11 ) 771 - 774 .
Pani S, Cook EJ, Horrocks JA, Jones JL, Speller RD ( 2010 ) . Characterization of breast tissue using energy-dispersive X-ray diffraction computed tomography . Appl Radiat Isot vol. 68 , ( 10 ) 1980 - 1987 .
da Silva RG, Tavora B, Robinson SD, Reynolds LE, Szekeres C, Lamar J, Batista S, Kostourou V et al. ( 2010 ) . Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF . Am J Pathol vol. 177 , ( 3 ) 1534 - 1548 .
Willis L, Alarcón T, Elia G, Jones JL, Wright NA, Tomlinson IPM, Graham TA, Page KM ( 2010 ) . Breast cancer dormancy can be maintained by small numbers of micrometastases . Cancer Res vol. 70 , ( 11 ) 4310 - 4317 .
Novitskaya V, Romanska H, Dawoud M, Jones JL, Berditchevski F ( 2010 ) . Tetraspanin CD151 Regulates Growth of Mammary Epithelial Cells in Three-Dimensional Extracellular Matrix: Implication for Mammary Ductal Carcinoma In situ . CANCER RES vol. 70 , ( 11 ) 4698 - 4708 .
Germain M, De Arcangelis A, Robinson SD, Baker M, Tavora B, D'Amico G, Silva R, Kostourou V et al. ( 2010 ) . Genetic ablation of the alpha 6-integrin subunit in Tie1Cre mice enhances tumour angiogenesis . J Pathol vol. 220 , ( 3 ) 370 - 381 .
Guttery DS, Hancox RA, Mulligan KT, Hughes S, Lambe SM, Pringle JH, Walker RA, Jones JL et al. ( 2010 ) . Association of invasion-promoting tenascin-C additional domains with breast cancers in young women . Breast Cancer Res vol. 12 , ( 4 )
Holliday DL, Maltby S, Moss MA, Hanby AM, Jones JL, Speirs V ( 2010 ) . Modelling breast cancer in a three-dimensional heterotypic culture system . BREAST CANCER RESEARCH . vol. 12 , S18 - S18 .
Cunha POR, Ornstein M, Jones JL ( 2010 ) . Progression of Ductal Carcinoma in Situ from the Pathological Perspective . BREAST CARE vol. 5 , ( 4 ) 233 - 239 .
Holliday DL, Brouilette KT, Markert A, Jones JL ( 2009 ) . A HUMAN HETEROTYPIC BREAST MODEL FOR TRANSLATIONAL STUDIES OF DUCTAL CARCINOMA IN SITU (DCIS) PROGRESSION . ANNALS OF ONCOLOGY . vol. 20 , 40 - 40 .
Middleton RK, Bown MJ, Lloyd GM, Jones JL, London NJ, Sayers RD ( 2009 ) . Characterisation of Interleukin-8 and monocyte chemoattractant protein-1 expression within the abdominal aortic aneurysm and their association with mural inflammation . Eur J Vasc Endovasc Surg vol. 37 , ( 1 ) 46 - 55 .
Holliday DL, Brouilette KT, Markert A, Gordon LA, Jones JL ( 2009 ) . Novel multicellular organotypic models of normal and malignant breast: tools for dissecting the role of the microenvironment in breast cancer progression . BREAST CANCER RES vol. 11 , ( 1 ) Article R3 ,
Hancox RA, Allen MD, Holliday DL, Edwards DR, Pennington CJ, Guttery DS, Shaw JA, Walker RA et al. ( 2009 ) . Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and growth by matrix metalloproteinase-dependent and independent mechanisms . Breast Cancer Res vol. 11 , ( 2 )
Mintz PJ, Habib NA, Jones JL, Giamas G, Lewis JS, Bowen RL, Coombes RC, Stebbing J ( 2008 ) . The phosphorylated membrane estrogen receptor and cytoplasmic signaling and apoptosis proteins in human breast cancer . CANCER vol. 113 , ( 6 ) 1489 - 1495 .
Duffy SW, Bowen RL, Ryan DA, Hart IR, Jones JL ( 2008 ) . Reply: Early onset of breast cancer in black British women: how reliable are the findings? . BRIT J CANCER vol. 99 , ( 6 ) 988 - 988 .
Bowen RL, Duffy SW, Ryan DA, Hart IR, Jones JL ( 2008 ) . Reply: Early onset of breast cancer in British black women . British Journal of Cancer vol. 98 , ( 12 )
Bowen RL, Duffy SW, Ryan DA, Hart IR, Jones JL ( 2008 ) . Early onset of breast cancer in British black women - Reply . BRIT J CANCER vol. 98 , ( 12 ) 2012 - 2012 .
Bowen R, Duffy S, Ryan D, Hart I, Jones L ( 2008 ) . Reply: Early onset breast cancer in black British women: a letter to the editor of British Journal of Cancer regarding early onset of breast cancer in a group of British black women . BRIT J CANCER vol. 98 , ( 8 ) 1483 - 1484 .
Gutierrez-Fernandez A, Fueyo A, Folgueras AR, Garabaya C, Pennington CJ, Pilgrim S, Edwards DR, Holliday DL et al. ( 2008 ) . Matrix metalloproteinase-8 functions as a metastasis suppressor through modulation of tumor cell adhesion and invasion . CANCER RES vol. 68 , ( 8 ) 2755 - 2763 .
Salama I, Malone PS, Mihaimeed F, Jones JL ( 2008 ) . A review of the S100 proteins in cancer . EJSO-EUR J SURG ONC vol. 34 , ( 4 ) 357 - 364 .
Varghese P, Gattuso JM, Mostafa AIH, Abdel-Rahman AT, Shenton KC, Ryan DA, Jones JL, Wells CA et al. ( 2008 ) . The role of radiotherapy in treating small early invasive breast cancer . Eur J Surg Oncol vol. 34 , ( 4 ) 369 - 376 .
Bowen RL, Duffy SW, Ryan DA, Hart IR, Jones JL ( 2008 ) . Early onset of breast cancer in a group of British black women . BRIT J CANCER vol. 98 , ( 2 ) 277 - 281 .
Modes V, Rodrigues CM, Nyquist N, Shaw JA, Jones JL, Walker RA ( 2008 ) . Altered myoepithelial cell expression and function in cancer-containing breasts . BREAST CANCER RESEARCH . vol. 10 , S25 - S25 .
Allen M, Mulligan K, Clark S, Hart I, Marshall JF, Jones JL ( 2008 ) . De novo expression of alpha(v)beta(6) integrin by myoepithelial cells in ductal carcinoma in situ may be an important marker of disease progression . BREAST CANCER RESEARCH . vol. 10 , S16 - S16 .
Payne SJL, Bowen RL, Jones JL, Wells CA ( 2008 ) . Predictive markers in breast cancer - the present . HISTOPATHOLOGY vol. 52 , ( 1 ) 82 - 90 .
Holliday DL, Mulligan KT, Jones JL ( 2007 ) . Development of in vitro models to study microenvironmental influences on breast cancer progression . BREAST CANCER RESEARCH AND TREATMENT . vol. 106 , S201 - S202 .
Jones JL, Thomas GJ, Duffy SW, Gabe R, Ellis I, Green A, Saha A, Mulligan KT et al. ( 2007 ) . Expression of alphavbeta6 supersedes Her2 and triple-negative/basal classification of breast cancer and defines novel subgroups with poor survival: implications for breast cancer classification and treatment . BREAST CANCER RESEARCH AND TREATMENT . vol. 106 , S11 - S11 .
Clark SE, Marshall JE, Hart IR, Carpenter R, Jones JL ( 2007 ) . Molecular profiling of DCIS: identification of distinct subgroups of potential prognostic importance . BREAST CANCER RESEARCH AND TREATMENT . vol. 106 , S221 - S221 .
Alcock RA, Allen MD, Holliday DL, Edwards DR, Pennington CL, Shaw JA, Walker RA, Pringle JH et al. ( 2007 ) . Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and proliferation through MMP-dependant and -independant mechanisms . BREAST CANCER RESEARCH AND TREATMENT . vol. 106 , S200 - S201 .
Hughes S, Agbaje O, Bowen RL, Holliday DL, Shaw JA, Duffy S, Jones JL ( 2007 ) . Matrix metalloproteinase single-nucleotide polymorphisms and haplotypes predict breast cancer progression . Clin Cancer Res vol. 13 , ( 22 Pt 1 ) 6673 - 6680 .
Hughes S, Jones JL ( 2007 ) . The use of multiple displacement amplified DNA as a control for methylation specific PCR, pyrosequencing, bisulfite sequencing and methylation-sensitive restriction enzyme PCR . BMC Mol Biol vol. 8 ,
Holliday DL, Hughes S, Shaw JA, Walker RA, Jones JL ( 2007 ) . Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion . Breast Cancer Res vol. 9 , ( 5 )
Edwards JG, Swinson DEB, Jones JL, Waller DA, O'Byrne KJ ( 2006 ) . EGFR expression: Associations with outcome and clinicopathological variables in malignant pleural mesothelioma . LUNG CANCER vol. 54 , ( 3 ) 399 - 407 .
Allen M, Mulligan K, Clark S, Hart I, Marshall J, Jones J ( 2006 ) . Functional analysis of normal and DCIS modified breast myoepithelial cells . Breast Cancer Research . vol. 8 ,
Bowen RL, Stebbing J, Jones LJ ( 2006 ) . A review of the ethnic differences in breast cancer . PHARMACOGENOMICS vol. 7 , ( 6 ) 935 - 942 .
Hughes S, Holliday D, Shaw J, Duffy S, Hart I, Jones L ( 2006 ) . Analysis of MMP single nucleotide polymorphisms in relation to breast cancer progression . JOURNAL OF PATHOLOGY . vol. 210 , 58 - 58 .
Lloyd K, Pringle JH, Alcock RA, Jones JL, Walker RA, Shaw JA ( 2006 ) . Expression of invasion promoting Tn-C isoforms in DCIS . JOURNAL OF PATHOLOGY . vol. 210 , 35 - 35 .
Nitch-Smith HL, Walker R, Hart IR, Carpenter R, Jones JL ( 2006 ) . Expression of the tenascin-binding alpha 9 beta 1 integrin in normal breast, DCIS and invasive breast cancer . JOURNAL OF PATHOLOGY . vol. 210 , 31 - 31 .
Wilson WRW, Anderton M, Schwalbe EC, Jones JL, Furness PN, Bell PRF, Thompson MM ( 2006 ) . Matrix metalloproteinase-8 and -9 are increased at the site of abdominal aortic aneurysm rupture . Circulation vol. 113 , ( 3 ) 438 - 445 .
Alcock RA, Pringle JH, Shaw JA, Holliday DL, Allen M, Walker RA, Jones JL ( 2006 ) . Functional analysis of altered Tenascin isoform expression in breast cancer . BREAST CANCER RESEARCH . vol. 8 , S11 - S11 .
Jones JL ( 2006 ) . Overdiagnosis and overtreatment of breast cancer - Progression of ductal carcinoma in situ: the pathological perspective . BREAST CANCER RES vol. 8 , ( 2 ) Article 204 ,
Grierson C, Holliday DL, Jameson JS, Pringle JH, Jones JL ( 2005 ) . Tenascin-C isoform expression in colorectal cancer . JOURNAL OF PATHOLOGY . vol. 207 , 39 - 39 .
Wilson WRW, Schwalbe EC, Jones JL, Bell PRF, Thompson MM ( 2005 ) . Matrix metalloproteinase 8 (neutrophil collagenase) in the pathogenesis of abdominal aortic aneurysm . BRITISH JOURNAL OF SURGERY . vol. 92 , 828 - 833 .
Shah A, Swain WA, Richardson D, Edwards J, Stewart DJ, Richardson CM, Swinson DEB, Patel D et al. ( 2005 ) . Phospho-Akt expression is associated with a favorable outcome in non-small cell lung cancer . CLIN CANCER RES vol. 11 , ( 8 ) 2930 - 2936 .
Sutton CD, Marshall LJ, Goddard JC, O'Byrne K, Garcia G, Jones JL, Dennison AR, Poston G et al. ( 2005 ) . Hypoxia and angiogenesis in colorectal liver metastases . BRITISH JOURNAL OF SURGERY . vol. 92 , 58 - 58 .
Walker RA, Rodrigues CM, Gordon-Weeks A, Luckett JC, Jones JL ( 2005 ) . Growth regulation is altered in cancer-containing breasts . BREAST CANCER RESEARCH AND TREATMENT . vol. 94 , S283 - S283 .
Mulligan KT, Wang H, Shaw JA, Hart IR, Jones JL ( 2005 ) . The tumour-suppressor function of breast myoepithelial cells is mediated in part through regulation of S100A9 . BREAST CANCER RESEARCH AND TREATMENT . vol. 94 , S285 - S285 .
Alcock RA, Holliday DL, Shaw JA, Walker RA, Pringle JH, Jones JL ( 2005 ) . Tumour-associated tenascin-C isoforms promote breast cancer cell invasion and proliferation . BREAST CANCER RESEARCH AND TREATMENT . vol. 94 , S188 - S188 .
Alcock RA, Adams M, Pringle JH, Shaw JA, Walker RA, Jones JL ( 2004 ) . Analysis of the functional significance of altered Tenascin isoform expression in breast cancer . JOURNAL OF PATHOLOGY . vol. 204 , 3A - 3A .
Luckett JCA, Shaw JA, Jones JL, Walker RA ( 2004 ) . Signal transduction and cell cycle regulation by the breast myoepithelial cells . JOURNAL OF PATHOLOGY . vol. 204 , 16A - 16A .
Holliday DL, Shaw JA, Walker RA, Jones JL ( 2004 ) . Stromal contribution to breast cancer cell invasion: Intrinsic genetic differences relate to invasion promoting ability . JOURNAL OF PATHOLOGY . vol. 204 , 2A - 2A .
Swinson DEB, Jones JL, Cox G, Richardson D, Harris AL, O'Byrne KJ ( 2004 ) . Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways . Int J Cancer vol. 111 , ( 1 ) 43 - 50 .
Molloy KJ, Thompson MM, Jones JL, Schwalbe EC, Bell PRF, Naylor AR, Loftus IM ( 2004 ) . Unstable carotid plaques exhibit raised matrix metalloproteinase-8 activity . Circulation vol. 110 , ( 3 ) 337 - 343 .
Sutton CD, Marshall LJ, Goddard JC, O'Byrne K, Garcia G, Jones JL, Dennison AR, Poston G et al. ( 2004 ) . Biological factors influencing angiogenesis and prognosis in resected colorectal liver metastases . BRITISH JOURNAL OF SURGERY . vol. 91 , 30 - 30 .
Porter S, Scott SD, Sassoon EM, Williams MR, Jones JL, Girling AC, Ball RY, Edwards DR ( 2004 ) . Dysregulated expression of adamalysin-thrombospondin genes in human breast carcinoma . CLIN CANCER RES vol. 10 , ( 7 ) 2429 - 2440 .
Jones JL, Shaw JA, Pringle JH, Walker RA ( 2003 ) . Primary breast myoepithelial cells exert an invasion-suppressor effect on breast cancer cells via paracrine down-regulation of MMP expression in fibroblasts and tumour cells . J Pathol vol. 201 , ( 4 ) 562 - 572 .
Tai SK, Tan OJK, Chow VTK, Jin RX, Jones JL, Tan PH, Jayasurya A, Bay BH ( 2003 ) . Differential expression of metallothionein 1 and 2 lsoforms in breast cancer lines with different invasive potential - Identification of a novel nonsilent metallothionein-1H mutant variant . AM J PATHOL vol. 163 , ( 5 ) 2009 - 2019 .
Edwards JG, Swinson DEB, Jones JL, Muller S, Waller DA, O'Byrne KJ ( 2003 ) . Tumor necrosis correlates with angiogenesis and is a predictor of poor prognosis in malignant mesothelioma . CHEST vol. 124 , ( 5 ) 1916 - 1923 .
Alcock RA, Shaw JA, Pringle JH, Walker RA, Jones JL ( 2003 ) . Expression of tenascin AD1 domain in breast is not specific to malignancy . JOURNAL OF PATHOLOGY . vol. 201 , 35A - 35A .
Al Bahlani S, Shaw JA, Whyman G, Potter L, Walker RA, Jones JL ( 2003 ) . Genetic alterations in epithelial and stromal cells of breast cancers and surrounds . JOURNAL OF PATHOLOGY . vol. 201 , 5A - 5A .
Gordon LA, Mulligan KT, Maxwell-Jones H, Adams M, Walker RA, Jones JL ( 2003 ) . Breast cell invasive potential relates to the myoepithelial phenotype . Int J Cancer vol. 106 , ( 1 ) 8 - 16 .
Marshall LJ, Sutton CD, Jones JL, O'Byrne K, Dennison AR, Poston G, Lloyd DM, Berry DP ( 2003 ) . Carbonic anhydrase ix independently predicts survival in colorectal liver metastases . BRITISH JOURNAL OF SURGERY . vol. 90 , 51 - 51 .
Edwards JG, McLaren J, Jones JL, Waller DA, O'Byrne KJ ( 2003 ) . Matrix metalloproteinases 2 and 9 (gelatinases A and B) expression in malignant mesothelioma and benign pleura . BRIT J CANCER vol. 88 , ( 10 ) 1553 - 1559 .
Chauhan H, Abraham A, Phillips JRA, Pringle JH, Walker RA, Jones JL ( 2003 ) . There is more than one kind of myofibroblast: analysis of CD34 expression in benign, in situ, and invasive breast lesions . J Clin Pathol vol. 56 , ( 4 ) 271 - 276 .
Swinson DEB, Jones JL, Richardson D, Wykoff C, Turley H, Pastorek J, Taub N, Harris AL et al. ( 2003 ) . Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer . J Clin Oncol vol. 21 , ( 3 ) 473 - 482 .
Squires MS, Hudson EA, Howells L, Sale S, Houghton CE, Jones JL, Fox LH, Dickens M et al. ( 2003 ) . Relevance of mitogen activated protein kinase (MAPK) and phosphotidylinositol-3-kinase/protein kinase B (PI3K/PKB) pathways to induction of apoptosis by curcumin in breast cells . Biochem Pharmacol vol. 65 , ( 3 ) 361 - 376 .
Shaw JA, Udokang K, Mosquera J-M, Chauhan H, Jones JL, Walker RA ( 2002 ) . Oestrogen receptors alpha and beta differ in normal human breast and breast carcinomas . J Pathol vol. 198 , ( 4 ) 450 - 457 .
Goddard JC, Sutton CD, Jones JL, O'Byrne KJ, Kockelbergh RC ( 2002 ) . Reduced thrombospondin-1 at presentation predicts disease progression in superficial bladder cancer . Eur Urol vol. 42 , ( 5 ) 464 - 468 .
Mulligan KT, Shaw JA, Gordon LA, Holliday DL, Luckett JA, Walker RA, Jones JL ( 2002 ) . Analysis of the tumour suppressor role of breast myoepithelial cells . J PATHOL vol. 198 , 3A - 3A .
Bamford WM, Saleem M, Kulbicki K, Walker RA, Jones JL ( 2002 ) . Expression of matrilysin (MMP-7) protein in benign and malignant breast . J PATHOL vol. 198 , 31A - 31A .
Dhillon J, Pavlou G, Jones JL, Walker RA ( 2002 ) . Expression of the cell adhesion molecule p120 differs between infiltrating ductal and infiltrating lobular carcinomas . J PATHOL vol. 198 , 30A - 30A .
Abrahams A, Chauhan H, Phillips J, Pringle JH, Walker RA, Jones JL ( 2002 ) . There is more than one kind of myofibroblast: analysis of CD34 expression in benign, in-situ and invasive breast lesions . J PATHOL vol. 198 , 31A - 31A .
Swinson DEB, Jones JL, Richardson D, Cox G, Edwards JG, O'Byrne KJ ( 2002 ) . Tumour necrosis is an independent prognostic marker in non-small cell lung cancer: correlation with biological variables . Lung Cancer vol. 37 , ( 3 ) 235 - 240 .
Adams M, Jones JL, Walker RA, Pringle JH, Bell SC ( 2002 ) . Changes in tenascin-C isoform expression in invasive and preinvasive breast disease . Cancer Res vol. 62 , ( 11 ) 3289 - 3297 .
Swinson DEB, Jones JL, Cox G, Richardson C, Richardson D, Allen C, O'Byrne KJ ( 2002 ) . Hypoxia inducible factor (HIF)-1 alpha in non-small cell lung cancer (NSCLC) . BRIT J CANCER vol. 86 , S28 - S28 .
Edwards JG, Swinson D, Jones JL, Cox G, O'Byrne KJ ( 2002 ) . Tumour necrosis correlates with angiogenesis and is a prognostic factor in malignant mesothelioma . BRIT J CANCER vol. 86 , S97 - S97 .
Swinson DEB, Lolljee J, Edwards JG, Jones JL, Cox G, Richardson D, O'Byrne KJ ( 2002 ) . beta-catenin in non-small cell lung cancer (NSCLC) . BRIT J CANCER vol. 86 , S59 - S60 .
Cox G, Jones JL, Andi A, Abrams KR, O'Byrne KJ ( 2001 ) . Bcl-2 is an independent prognostic factor and adds to a biological model for predicting outcome in operable non-small cell lung cancer . LUNG CANCER-J IASLC vol. 34 , ( 3 ) 417 - 426 .
O'Byrne KJ, Cox G, Swinson D, Richardson D, Edwards JG, Lolljee J, Andi A, Koukourakis MI et al. ( 2001 ) . Towards a biological staging model for operable non-small cell lung cancer . LUNG CANCER . vol. 34 , S83 - S89 .
Edwards JG, Cox G, Andi A, Jones JL, Walker RA, Waller DA, O'Byrne KJ ( 2001 ) . Angiogenesis is an independent prognostic factor in malignant mesothelioma . BRIT J CANCER vol. 85 , ( 6 ) 863 - 868 .
Phillips JRA, Adams M, Gordon LA, Walker RA, Jones JL ( 2001 ) . Characterisation of stromal changes in invasive and pre-invasive breast disease . J PATHOL vol. 195 , 28A - 28A .
Runswick SK, O'Hare MJ, Jones L, Streuli CH, Garrod DR ( 2001 ) . Desmosomal adhesion regulates epithelial morphogenesis and cell positioning . NAT CELL BIOL vol. 3 , ( 9 ) 823 - 830 .
Saleem M, Gordon LA, Adams M, Walker RA, Jones JL ( 2001 ) . Effect of matrilysin (MMP-7) on breast cancer cell behaviour . J PATHOL vol. 195 , 7A - 7A .
Kovacs A, Dhillon J, Jones JL, Walker RA ( 2001 ) . Expression of P- and N-cadherin in breast carcinomas . J PATHOL vol. 195 , 27A - 27A .
Banerjee AR, Jones JL, Birchall JP, Powe DG ( 2001 ) . Localization of matrix metalloproteinase 1 in cholesteatoma and deep meatal skin . OTOL NEUROTOL vol. 22 , ( 5 ) 579 - 581 .
Cox G, Jones JL, Andi A, Waller DA, O'Byrne KJ ( 2001 ) . A biological staging model for operable non-small cell lung cancer . Thorax vol. 56 , ( 7 ) 561 - 566 .
Goddard JC, Sutton CD, Jones JL, O'Byrne KJ, Kockelbergh RC ( 2001 ) . Reduction in immunohistochemical staining of thrombospondin-1 predicts progression in superficial bladder cancer . BRIT J CANCER vol. 85 , 35 - 35 .
Goddard JC, Sutton CD, Jones JL, Berry DP, O'Byrne KJ, Kockelbergh RC ( 2001 ) . Reduction in thrombospondin 1 expression significantly correlates with disease progression in superficial bladder cancer . BRIT J SURG vol. 88 , 8 - 8 .