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Research

Publications: Dr David Gould

Khan AN, Ermakov A, Saunders T, Giddens H, Gould D, Sukhorukov G, Hao Y ( 2022 ) . Electrical characterization of micron sized chambers used as a depot for drug delivery . IEEE Sensors Journal
Kudryavtseva V, Bukatin A, Vyacheslavova E, Gould D, Sukhorukov GB ( 2022 ) . Printed asymmetric microcapsules: Facile loading and multiple stimuli-responsiveness . Biomaterials Advances vol. 136 ,
Young ER, Gould DJ, Hart SL ( 2021 ) . Delivery of disease-responsive mini-intronic plasmids with cationic liposome vectors for rheumatoid arthritis . HUMAN GENE THERAPY . vol. 32 , A132 - A132 .
Riveiro ME, Frapolli R, Taraboletti GTG, Rezai K, Meroni M, Russo M, Borsotti P, Schultz C et al. ( 2021 ) . A novel LAP-IL2 fusion protein elicits efficacy as single agent in syngeneic renal and melanoma mouse models . CANCER RESEARCH . vol. 81 ,
Riveiro ME, Frapolli R, Taraboletti GTG, Rezai K, Meroni M, Russo M, Borsotti P, Schultz C et al. ( 2021 ) . Abstract 916: A novel LAP-IL2 fusion protein elicits efficacy as single agent in syngeneic renal and melanoma mouse models . Cancer Research vol. 81 , ( 13_Supplement ) 916 - 916 .
Young ER, Nikolaenko V, Heywood W, Gould DJ, Hart SL ( 2021 ) . Design and Optimisation of Synovial-Targeted Non-Viral Lipid Nanoparticles for Systemic Delivery in Rheumatoid Arthritis . MOLECULAR THERAPY . vol. 29 , 228 - 228 .
Kudryavtseva V, Boi S, Read J, Gould D, Szewczyk PK, Stachewicz U, Kiryukhin MV, Pastorino L et al. ( 2021 ) . Micro-sized “pelmeni” - A universal microencapsulation approach overview . Materials and Design vol. 202 ,
Kudryavtseva V, Boi S, Read J, Guillemet R, Zhang J, Udalov A, Shesterikov E, Tverdokhlebov S et al. ( 2021 ) . Biodegradable defined shaped printed polymer microcapsules for drug delivery . ACS Applied Materials and Interfaces vol. 13 , ( 2 ) 2371 - 2381 .
Sindeeva OA, Kopach O, Kurochkin MA, Sapelkin A, Gould DJ, Rusakov DA, Sukhorukov GB ( 2020 ) . Polylactic Acid-Based Patterned Matrixes for Site-Specific Delivery of Neuropeptides On-Demand: Functional NGF Effects on Human Neuronal Cells . Frontiers in Bioengineering and Biotechnology vol. 8 ,
Young E, Gould DJ, Hart SL ( 2020 ) . Targeted Non-Viral Delivery of Mini-Intronic Plasmids for Rheumatoid Arthritis . MOLECULAR THERAPY . vol. 28 , 471 - 471 .
Read JE, Luo D, Chowdhury TT, Flower RJ, Poston RN, Sukhorukov GB, Gould DJ ( 2020 ) . Magnetically responsive layer-by-layer microcapsules can be retained in cells and under flow conditions to promote local drug release without triggering ROS production . Nanoscale vol. 12 , ( 14 ) 7735 - 7748 .
Young E, Gould D, Hart S ( 2020 ) . Toward gene therapy in rheumatoid arthritis . Expert Review of Precision Medicine and Drug Development1 - 11 .
Luo D, Poston RN, Gould DJ, Sukhorukov GB ( 2019 ) . Magnetically targetable microcapsules display subtle changes in permeability and drug release in response to a biologically compatible low frequency alternating magnetic field . Materials Science and Engineering C vol. 94 , 647 - 655 .
Popov AL, Popova N, Gould DJ, Shcherbakov AB, Sukhorukov GB, Ivanov VK ( 2018 ) . Ceria Nanoparticles-Decorated Microcapsules as a Smart Drug Delivery/Protective System: Protection of Encapsulated P. pyralis Luciferase . ACS Appl Mater Interfaces vol. 10 , ( 17 ) 14367 - 14377 .
Gai M, Kurochkin MA, Li D, Khlebtsov BN, Dong L, Tarakina N, Poston R, Gould DJ et al. ( 2018 ) . In-situ NIR-laser mediated bioactive substance delivery to single cell for EGFP expression based on biocompatible microchamber-arrays . J Control Release vol. 276 , 84 - 92 .
Schultz CMA, Mullen L, Gould DJ, Chernajovsky Y ( 2017 ) . Progranulin and derivatives can be employed as latent dual-function chondrogenic and anti-inflammatory therapeutics for the treatment of arthritis . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 98 , A11 - A11 .
Gould D ( 2017 ) . Mammalian Synthetic Promoters . Humana Press
Timin AS, Gould DJ, Sukhorukov GB ( 2017 ) . Multi-layer microcapsules: fresh insights and new applications . Expert Opin Drug Deliv vol. 14 , ( 5 ) 583 - 587 .
Yousaf N, Gould D ( 2017 ) . Demonstrating Interactions of Transcription Factors with DNA by Electrophoretic Mobility Shift Assay . vol. 1651 ,
Gould D ( 2017 ) . Initial Considerations Before Designing a Promoter Construct . vol. 1651 ,
Mohamed H, Gould D ( 2017 ) . PCR Assembly of Synthetic Promoters . vol. 1651 ,
Yousaf N, Gould D ( 2017 ) . The Tetracycline Responsive System .
CATTELL MJ, Sukhorukov G, Gould DJ, shahid S, Zhang, X, Luo DONG ( 2016 ) . Electrospun poly (lactic acid) fibers containing novel chlorhexidine particles with sustained antibacterial activity . Biomaterials Science
Svenskaya YI, Pavlov AM, Gorin DA, Gould DJ, Parakhonskiy BV, Sukhorukov GB ( 2016 ) . Photodynamic therapy platform based on localized delivery of photosensitizer by vaterite submicron particles . Colloids Surf B Biointerfaces vol. 146 , 171 - 179 .
Mohamed H, Chernajovsky Y, Gould D ( 2016 ) . Assembly PCR synthesis of optimally designed, compact, multi-responsive promoters suited to gene therapy application . Scientific Reports vol. 6 , 29388 - 29388 .
Luo D, Gould DJ, Sukhorukov GB ( 2016 ) . Local and Sustained Activity of Doxycycline Delivered with Layer-by-Layer Microcapsules . Biomacromolecules vol. 17 , ( 4 ) 1466 - 1476 .
Pavlov AM, Gabriel SA, Sukhorukov GB, Gould DJ ( 2015 ) . Improved and targeted delivery of bioactive molecules to cells with magnetic layer-by-layer assembled microcapsules . Nanoscale vol. 7 , ( 21 ) 9686 - 9693 .
Subang MC, Fatah R, Wu Y, Hannaman D, Rice J, Evans CF, Chernajovsky Y, Gould D ( 2015 ) . Effects of APC de-targeting and GAr modification on the duration of luciferase expression from plasmid DNA delivered to skeletal muscle . Current Gene Therapy vol. 15 , ( 1 ) 3 - 14 .
Mullen L, Adams G, Foster J, Vessillier S, Köster M, Hauser H, Layward L, Gould D et al. ( 2014 ) . A comparative study of matrix metalloproteinase and aggrecanase mediated release of latent cytokines at arthritic joints . Ann Rheum Dis vol. 73 , ( 9 ) 1728 - 1736 .
Muhammad H, Taher T, Mullen L, Pastan I, Marshall J, Chernajovsky Y, Gould D, Mageed R ( 2014 ) . Development of a novel approach for targeted delivery of siRNA to B lymphocytes with a potential application in cancer . HUMAN GENE THERAPY . vol. 25 , A5 - A5 .
Mohamed H, Chernajovsky Y, Gould D ( 2014 ) . Development of novel transcriptionally responsive synthetic promoters for therapeutic gene expression during disease activity . HUMAN GENE THERAPY . vol. 25 , A8 - A8 .
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljević N, Chaplin T et al. ( 2014 ) . Identification of ZDHHC14 as a novel human tumour suppressor gene . J Pathol vol. 232 , ( 5 ) 566 - 577 .
Koutsokeras A, Purkayastha N, Rigby A, Subang MC, Sclanders M, Vessillier S, Mullen L, Chernajovsky Y et al. ( 2014 ) . Erratum: Generation of an efficiently secreted, cell penetrating NF-?B inhibitor (FASEB Journal (2014) 28 (373-381) DOI: 10.1096/fj.13-236570) . FASEB Journal vol. 28 , ( 6 )
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljevíc N, Chaplin T et al. ( 2014 ) . Erratum:Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol (2014); 232: 566-577)) . Journal of Pathology vol. 234 , ( 1 )
Koutsokeras A, Purkayastha N, Rigby A, Subang MC, Sclanders M, Vessillier S, Mullen L, Chernajovsky Y et al. ( 2014 ) . Generation of an efficiently secreted, cell penetrating NF-κB inhibitor . FASEB J vol. 28 , ( 1 ) 373 - 381 .
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Marzec J, Vasiljevic N, Chaplin T, Foster JM et al. ( 2014 ) . Identification of ZDHHC14 as a novel human tumour suppressor: gene . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S90 - S90 .
Mullen L, Rigby A, Sclanders M, Adams G, Mittal G, Colston J, Fatah R, Subang C et al. ( 2014 ) . Latency can be conferred to a variety of cytokines by fusion with latency-associated peptide from TGF-β . Expert Opin Drug Deliv vol. 11 , ( 1 ) 5 - 16 .
Mullen L, Adams G, Layward L, Vessillier S, Annenkov A, Mittal G, Rigby A, Sclanders M et al. ( 2014 ) . Latent cytokines for targeted therapy of inflammatory disorders . Expert Opin Drug Deliv vol. 11 , ( 1 ) 101 - 110 .
Pavlov AM, Sukhorukov GB, Gould DJ ( 2013 ) . Location of molecules in layer-by-layer assembled microcapsules influences activity, cell delivery and susceptibility to enzyme degradation . J Control Release vol. 172 , ( 1 ) 22 - 29 .
Viale DL, Cafferata EG, Gould D, Rotondaro C, Chernajovsky Y, Curiel DT, Podhajcer OL, Veronica Lopez M ( 2013 ) . Therapeutic improvement of a stroma-targeted CRAd by incorporating motives responsive to the melanoma microenvironment . J Invest Dermatol vol. 133 , ( 11 ) 2576 - 2584 .
Gould D ( 2013 ) . Gene doping: gene delivery for olympic victory . Br J Clin Pharmacol vol. 76 , ( 2 ) 292 - 298 .
Mohamed H, Chernajovsky Y, Gould D ( 2013 ) . Development of novel transciptionally responsive synthetic promoters for therapeutic gene expression during disease activity . HUMAN GENE THERAPY . vol. 24 , A36 - A36 .
Muhammad H, Taher T, Mullen L, Pastan I, Chernajovsky Y, Gould D, Mageed R ( 2013 ) . Generation of a secreted scFv for specific delivery of siRNA to B-lymphocytes . HUMAN GENE THERAPY . vol. 24 , A36 - A36 .
Pavlov AM, Sukhorukov GB, Gould DJ ( 2013 ) . Lessons in microcapsule assembly from imaging delivery of a bioluminescent enzyme . Biomacromolecules vol. 14 , ( 3 ) 608 - 612 .
CHERNAJOVSKY Y, Mullen L, Vessillier S, Rigby A, Gould DJ, Fatah R, Adams G, Koutsokeras A et al. ( 2013 ) . Development of latent cytokine fusion proteins . Fusion protein technologies for biopharmaceuticals: Applications and Challenges , Editors: Schmidt, S , Wiley and Blackwell
Leinster DA, Kulbe H, Everitt G, Thompson R, Perretti M, Gavins FNE, Cooper D, Gould D et al. ( 2012 ) . The peritoneal tumour microenvironment of high-grade serous ovarian cancer . J Pathol vol. 227 , ( 2 ) 136 - 145 .
Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Chaplin T, Xue L, Xu M et al. ( 2012 ) . Abstract 4858: Identification of ZDHHC14 as a novel tumor suppressor gene commonly downregulated in human cancers . Cancer Research vol. 72 , ( 8_Supplement ) 4858 - 4858 .
Subang MC, Fatah R, Bright C, Blanco P, Berenstein M, Wu Y, Podhajcer OL, Winyard PG et al. ( 2012 ) . A novel hybrid promoter responsive to pathophysiological and pharmacological regulation . J Mol Med (Berl) vol. 90 , ( 4 ) 401 - 411 .
Hughes C, Faurholm B, Dell'Accio F, Manzo A, Seed M, Eltawil N, Marrelli A, Gould D et al. ( 2011 ) . TARGETING THERAPEUTICS TO ARTHRITIC JOINTS . RHEUMATOLOGY . vol. 50 , 127 - 127 .
Battery L, Solomon A, Gould D ( 2011 ) . Gene Doping: Olympic Genes for Olympic Dreams . J R Soc Med vol. 104 , 494 - 500 .
Stok KS, Noel D, Apparailly F, Gould D, Chernajovsky Y, Jorgensen C, Muller R ( 2010 ) . Quantitative imaging of cartilage and bone for functional assessment of gene therapy approaches in experimental arthritis . J TISSUE ENG REGEN M vol. 4 , ( 5 ) 387 - 394 .
Hughes C, Faurholm B, Dell'Accio F, Manzo A, Seed M, Eltawil N, Marrelli A, Gould D et al. ( 2010 ) . Human single-chain variable fragment that specifically targets arthritic cartilage . Arthritis Rheum vol. 62 , ( 4 ) 1007 - 1016 .
Subang MC, Gould D ( 2010 ) . Delivery and application of Plasmid DNA in Arthritis Gene Therapy . Gene Therapy for Autoimmune and Inflammatory diseases’ Milestones in Drug Therapy , Editors: Chernajovsky, Y, Robbins, PD , BIRKHAUSER
Vilalta M, Jorgensen C, Degano IR, Chernajovsky Y, Gould D, Noel D, Andrades JA, Becerra J et al. ( 2009 ) . Dual luciferase labelling for non-invasive bioluminescence imaging of mesenchymal stromal cell chondrogenic differentiation in demineralized bone matrix scaffolds . BIOMATERIALS vol. 30 , ( 28 ) 4986 - 4995 .
Jawad AS, Taher TE, Rahim A, D'Acquisto F, Gould D, Mageed RA ( 2009 ) . SELECTIVE TARGETING OF THE CANONICAL OR ALTERNATIVE NF-kappa B PATHWAY REVEALS NEW INSIGHTS INTO MECHANISMS OF B-LYMPHOCYTE SURVIVAL AND SELECTION . RHEUMATOLOGY . vol. 48 , I30 - I31 .
Lopez MV, Viale DL DL, Cafferata EG, Bravo AI, Carbone C, Gould D, Chernajovsky Y, Podhajcer OL ( 2009 ) . Tumor associated stromal cells play a critical role on the outcome of the oncolytic efficacy of conditionally replicative adenoviruses . PLoS ONE vol. 4 ,
Vilalta M, Degano IR, Bago J, Gould D, Santos M, Garcia-Arranz M, Ayats R, Fuster C et al. ( 2008 ) . Biodistribution, Long-term Survival, and Safety of Human Adipose Tissue-derived Mesenchymal Stem Cells Transplanted in Nude Mice by High Sensitivity Non-invasive Bioluminescence Imaging . STEM CELLS DEV vol. 17 , ( 5 ) 993 - 1003 .
Taher TE, Tulone C, Fatah R, D'Acquisto F, Gould DJ, Mageed RA ( 2008 ) . Repopulation of B-lymphocytes with restricted gene expression using haematopoietic stem cells engineered with lentiviral vectors . Gene Ther vol. 15 , ( 13 ) 998 - 1006 .
Subang MC, Fatah R, Wu Y, Chernajovsky Y, Gould DJ ( 2008 ) . Progress with the delivery of biologic molecules by gene therapy in arthritis using plasmid DNA . HUMAN GENE THERAPY . vol. 19 , 418 - 418 .
Subang MC, Rice J, Fatah R, Wu Y, Chernajovsky Y, Gould DJ ( 2008 ) . Strategies to prevent immunogenicity of foreign intracellular proteins . HUMAN GENE THERAPY . vol. 19 , 421 - 421 .
Gould DJ, Chernajovsky Y ( 2007 ) . Novel delivery methods to achieve immunomodulation . Curr Opin Pharmacol vol. 7 , ( 4 ) 445 - 450 .
Khoury M, Adriaansen J, Vervoordeldonk MJBM, Gould D, Chernajovsky Y, Bigey P, Bloquel C, Scherman D et al. ( 2007 ) . Inflammation-inducible anti-TNF gene expression mediated by intra-articular injection of serotype 5 adeno-associated virus reduces arthritis . J GENE MED vol. 9 , ( 7 ) 596 - 604 .
Khoury M, Adriaansen J, Vervoordeldonk MJBM, Gould D, Chernajovsky Y, Bigey P, Bloquel C, Scherman D et al. ( 2007 ) . Inflammation-inducible anti-TNF gene expression by intra-articular injection of serotype 5 adeno-associated virus reduces arthritis . ANNALS OF THE RHEUMATIC DISEASES . vol. 66 , A56 - A56 .
Kulbe H, Thompson R, Wilson JL, Robinson S, Hagemann T, Fatah R, Gould D, Ayhan A et al. ( 2007 ) . The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells . CANCER RES vol. 67 , ( 2 ) 585 - 592 .
Gould D, Yousaf N, Fatah R, Subang MC, Chernajovsky Y ( 2007 ) . Gene therapy with an improved doxycycline-regulated plasmid encoding a tumour necrosis factor-alpha inhibitor in experimental arthritis . ARTHRITIS RES THER vol. 9 , ( 1 ) Article R7 ,
Adriaansen J, Khoury M, de Cortie CJ, Fallaux FJ, Bigey P, Scherman D, Gould D, Chernajovsky Y et al. ( 2007 ) . Reduction of arthritis following intra-articular administration of an adeno-associated virus serotype 5 expressing a disease-inducible TNF blocking agent . Ann Rheum Dis vol. 66 , 1143 - 1150 .
Lopez MV, Blanco P, Viale DL, Cafferata EG, Carbone C, Gould D, Chernajovsky Y, Podhajcer OL ( 2006 ) . Expression of a suicidal gene under control of the human secreted protein acidic and rich in cysteine (SPARC) promoter in tumor or stromal cells led to the inhibition of tumor cell growth . MOL CANCER THER vol. 5 , ( 10 ) 2503 - 2511 .
CHERNAJOVSKY Y, Gould D, Podhajcer OL, Cafferata EA, Carbone C, Viale D, Blanco P, Lopez MV ( 2006 ) . Expression of suicidal gene under control of the human SPARC promoter in tumor or stromal cells led to the inhibition of tumor cell growth . Mol. Cancer Ther. vol. 5 , ( 10 ) 2503 - 2511 .
Adriaansen J, Khoury M, de Cortie K, Bigey P, Sherman D, Gould D, Chernajovsky Y, Jorgensen C et al. ( 2006 ) . Suppression of inflammation following intra-articular gene therapy with recombinant AAV5-Chimeric TNFR-Ig vector under an inducible promoter in animal models of rheumatoid arthritis . ARTHRITIS AND RHEUMATISM . vol. 54 , S176 - S177 .
Khoury M, Adriaansen J, Louis-Plence P, Noel D, Bigey P, de Cortie C, Gould D, Vervoordeldonk M et al. ( 2006 ) . Amelioration of Arthritis after Local Delivery of an Adeno-Associated Virus Type 6 Expressing a TNF-Blocking Agent under a Disease-Inducible Promoter . MOLECULAR THERAPY vol. 13 , S409 - S409 .
Lopez MV, Viale D, Cafferata EG, Macio DR, Gould D, Chernajovsky Y, Podhajcer OL ( 2006 ) . 777. A Novel Pan-Oncolytic Adenovirus Therapeutically Effective in Different Cancer Cell Types . Molecular Therapy . vol. 13 , s300 - s301 .
Hagemann T, GOULD DJ, Wilson J, Fatah R, Robinson S, Kulbe H, Thompson R, Blakwill F et al. ( 2006 ) . The inflammatory cytokine TNF-á generates an autocrine tumor- promoting network in epithelial ovarian cancer cells . Cancer Res
Yousaf N, Gould DJ, Aganna E, Hammond L, Mirakian RM, Turner MD, Hitman GA, McDermott MF et al. ( 2005 ) . Tumor necrosis factor receptor I from patients with tumor necrosis factor receptor-associated periodic syndrome interacts with wild-type tumor necrosis factor receptor I and induces ligand-independent NF-kappaB activation . Arthritis Rheum vol. 52 , ( 9 ) 2906 - 2916 .
Chernajovsky Y, Gould DJ, Podhajcer OL ( 2004 ) . Gene therapy for autoimmune diseases: quo vadis? . Nat Rev Immunol vol. 4 , ( 10 ) 800 - 811 .
Gould DJ, Chernajovsky Y ( 2004 ) . Endogenous GATA factors bind the core sequence of the tetO and influence gene regulation with the tetracycline system . Mol Ther vol. 10 , ( 1 ) 127 - 138 .
Gould DJ, Chernajovsky Y ( 2004 ) . Application of regulatable vectors in gene therapy of experimental arthritis . ARTHRITIS RESEARCH & THERAPY . vol. 6 , S27 - S27 .
CHERNAJOVSKY Y, Gould DJ, Podhajcer OL ( 2004 ) . Genetic Interventions for the treatment of autoimmune diseases: Quo Vadis? . Nat Rev Immunol vol. 4 , ( 10 ) 800 - 811 .
Gould DJ, Bright C, Chernajovsky Y ( 2004 ) . Inhibition of established collagen-induced arthritis with a tumour necrosis factor-alpha inhibitor expressed from a self-contained doxycycline regulated plasmid . Arthritis Res Ther vol. 6 , ( 2 ) R103 - R113 .
Chernajovsky Y, Vessillier S, Adams G, Gofur Y, Subang MC, Annenkov A, Favorov P, Daly G et al. ( 2003 ) . Development of new molecules, vectors and cells for therapy of arthritis . JOINT BONE SPINE vol. 70 , ( 6 ) 474 - 476 .
Chernajovsky Y, Vessillier S, Adams G, Gofur Y, Subang MC, Annenkov A, Favorov P, Daly G et al. ( 2003 ) . Développement de nouvelles molécules, vecteurs et cellules thérapeutiques dans les arthrites . Revue du Rhumatisme vol. 70 , ( 10-11 ) 846 - 848 .
Gould DJ, Favorov P ( 2003 ) . Vectors for the treatment of autoimmune disease . GENE THER vol. 10 , ( 10 ) 912 - 927 .
CHERNAJOVSKY Y, Gould D, Dreja H, Triantaphyllopoulos K ( 2003 ) . Interferon-beta gene therapy for the treatment of arthritis . Methods Mol Biol. vol. 215 , 171 - 180 .
Gould DJ ( 2002 ) . Inducible diabetes and transgene expression in a single mouse: a tool to elucidate autoimmune mechanisms . TRANSGENIC RES vol. 11 , ( 6 ) 583 - 585 .
Chernajovsky Y, Dreja H, Triantaphyllopoulos K, Gould D ( 2002 ) . Interferon-β Gene Therapy for the Treatment of Arthritis . Cytokines and Colony Stimulating Factors , vol. 215 ,
Dai L, O'Shaughnessy MC, Gould D, Claxson A, Marklund S, Kidd B, Chernajovsky Y, Winyard PG ( 2002 ) . SUPPRESSION OF INFLAMMATION BY ANTIOXIDANT GENE THERAPY IN AN ANTIGEN-INDUCED ARTHRITIS MODEL . RHEUMATOLOGY vol. 41 , 34 - 34 .
Gould D ( 2001 ) . Targeted arthritis gene therapy with T cells . Arthritis Research & Therapy vol. 3 , ( 1 )
Gould DJ, Berenstein M, Dreja H, Ledda F, Podhajcer OL, Chernajovsky Y ( 2000 ) . A novel doxycycline inducible autoregulatory plasmid which displays 'on'/'off' regulation suited to gene therapy applications . GENE THER vol. 7 , ( 24 ) 2061 - 2070 .
Chernajovsky Y, Dreja H, Daly G, Annenkov A, Gould D, Adams G, Croxford JL, Baker D et al. ( 2000 ) . Immuno- and genetic therapy in autoimmune diseases . Genes Immun vol. 1 , ( 5 ) 295 - 307 .
Chernajovsky Y, Gould D, Annenkov A, Dreja H, Daly G, Rabinovich GA, Croxford L, Baker D et al. ( 1999 ) . Immunotherapy of auto-immune diseases by gene transfer . Biochem Soc Trans vol. 27 , ( 6 ) 869 - 873 .
Chernajovsky Y, Gould D, Annenkov A, Dreja H, Daly G, Rabinovich GA, Croxford L, Baker D et al. ( 1999 ) . IMMUNOTHERAPY OF AUTOIMMUNE DISEASES BY GENE TRANSFER . Biochemical Society Transactions vol. 27 , ( 5 ) a137 - a137 .
Chernajovsky Y, Annenkov A, Herman C, Triantaphyllopoulos K, Gould D, Dreja H, Moyes SP, Croxford JL et al. ( 1998 ) . Gene therapy for rheumatoid arthritis. Theoretical considerations . Drugs and Aging vol. 12 , ( 1 ) 29 - 41 .