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Publications: Prof William Drake

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Grant B, Ratnayake G, Williams CL, Long A, Halsall DJ, Semple RK, Cavenagh JD, Drake WM et al. ( 2023 ) . Resolution of dysglycaemia after treatment of monoclonal gammopathy of endocrine significance . European Journal of Endocrinology vol. 189 , ( 6 ) k25 - k29 .
Goodchild E, Senanayake R, Wu X, Bashari W, Salsbury J, Argentesi G, O'Toole SM, McFarlane J et al. ( 2023 ) . FRI156 Novel Radiolabeled Ligand, Para-chloro-2-[18F]fluoroethyletomidate (CETO) Is Equivalent To [11C]metomidate-PET (MTO) For The Lateralisation Of Primary Aldosteronism (PA) . Journal of the Endocrine Society vol. 7 , ( Supplement_1 )
Argentesi G, Wu X, Ney A, Goodchild E, Laycock K, Lee Y-N, Senanayake R, MacFarlane J et al. ( 2023 ) . THU594 Outcome Data From Fabulas: A Feasibility Study Of Radiofrequency Endoscopic Ablation, With Ultrasound Guidance, As A Non-surgical, Adrenal Sparing Treatment For Aldosterone Producing Adenomas . Journal of the Endocrine Society vol. 7 , ( Supplement_1 )
Azizan EAB, Drake WM, Brown MJ ( 2023 ) . Primary aldosteronism: molecular medicine meets public health . Nature Reviews Nephrology vol. 19 , ( 12 ) 788 - 806 .
Lee Y-N, Drake WM ( 2023 ) . Radiofrequency Ablation in Primary Aldosteronism . Experimental and Clinical Endocrinology & Diabetes vol. 131 , ( 07/08 ) 438 - 442 .
Hamblin R, Fountas A, Lithgow K, Loughrey PB, Bonanos E, Shinwari SK, Mitchell K, Shah S et al. ( 2023 ) . Natural history of non-functioning pituitary microadenomas: results from the UK non-functioning pituitary adenoma consortium . European Journal of Endocrinology vol. 189 , ( 1 ) 87 - 95 .
Wu X, Azizan EAB, Goodchild E, Garg S, Hagiyama M, Cabrera CP, Fernandes-Rosa FL, Boulkroun S et al. ( 2023 ) . Somatic mutations of CADM1 in aldosterone-producing adenomas and gap junction-dependent regulation of aldosterone production . Nature Genetics vol. 55 , ( 6 ) 1009 - 1021 .
Kaniuka-Jakubowska S, Levy MJ, Pal A, Abeyaratne D, Drake WM, Kyriakakis N, Murray RD, Orme SM et al. ( 2023 ) . A study of acromegaly-associated headache with somatostatin analgesia . Endocrine Related Cancer vol. 30 , ( 3 )
Wu X, Senanayake R, Goodchild E, Bashari WA, Salsbury J, Cabrera CP, Argentesi G, O’Toole SM et al. ( 2023 ) . [11C]metomidate PET-CT versus adrenal vein sampling for diagnosing surgically curable primary aldosteronism: a prospective, within-patient trial . Nature Medicine vol. 29 , ( 1 ) 190 - 202 .
Koh CH, Khan DZ, Digpal R, Horsfall HL, Ali AMS, Baldeweg SE, Bouloux P-M, Dorward NL et al. ( 2023 ) . The clinical outcomes of imaging modalities for surgical management Cushing’s disease – A systematic review and meta-analysis . Frontiers in Endocrinology vol. 13 ,
Tufton N, Hearnden RJ, Berney DM, Drake WM, Parvanta L, Chapple JP, Akker SA ( 2022 ) . The immune cell infiltrate in the tumour microenvironment of phaeochromocytomas and paragangliomas . Endocrine Related Cancer vol. 29 , ( 11 ) 589 - 598 .
Perros P, Basu A, Boelaert K, Dayan C, Vaidya B, Williams GR, Lazarus JH, Hickey J et al. ( 2022 ) . Postradioiodine Graves' management: The PRAGMA study . Clinical Endocrinology vol. 97 , ( 5 ) 664 - 675 .
Zhou J, Azizan EAB, Cabrera CP, Fernandes-Rosa FL, Boulkroun S, Argentesi G, Cottrell E, Amar L et al. ( 2021 ) . Somatic mutations of GNA11 and GNAQ in CTNNB1-mutant aldosterone-producing adenomas presenting in puberty, pregnancy or menopause . Nature Genetics
O’Toole SM, Hornby C, Sze WC, Hannon MJ, Akker SA, Druce MR, Waterhouse M, Dawnay A et al. ( 2021 ) . Performance evaluation of scoring systems for predicting post‐operative hypertension cure in primary aldosteronism . Clinical Endocrinology vol. 95 , ( 4 ) 576 - 586 .
Stiles CE, Lloyd G, Bhattacharyya S, Steeds RP, Boomla K, Bestwick JP, Drake WM ( 2020 ) . Incidence of Cabergoline-Associated Valvulopathy in Primary Care Patients With Prolactinoma Using Hard Cardiac Endpoints . The Journal of Clinical Endocrinology & Metabolism vol. 106 , ( 2 ) e711 - e720 .
Ohno Y, Naruse M, Beuschlein F, Schreiner F, Parasiliti-Caprino M, Deinum J, Drake WM, Fallo F et al. ( 2020 ) . Adrenal Venous Sampling–Guided Adrenalectomy Rates in Primary Aldosteronism: Results of an International Cohort (AVSTAT) . The Journal of Clinical Endocrinology & Metabolism vol. 106 , ( 3 ) e1400 - e1407 .
Marques P, Magalhães D, Caimari F, Hernández RL, Collier D, Lim C, Stals K, Ellard S et al. ( 2020 ) . Phenotypic differences between patients with familial pituitary neuroendocrine tumours due to MEN1 or AIP mutations . Endocrine Abstracts
O’Toole SM, Sze W-CC, Chung T-T, Akker SA, Druce MR, Waterhouse M, Pitkin S, Dawnay A et al. ( 2020 ) . Low-grade Cortisol Cosecretion Has Limited Impact on ACTH-stimulated AVS Parameters in Primary Aldosteronism . The Journal of Clinical Endocrinology & Metabolism vol. 105 , ( 10 ) e3776 - e3784 .
LeCain M, Fraterrigo G, Drake WM ( 2020 ) . Induced Lactation in a Mother Through Surrogacy With Complete Androgen Insensitivity Syndrome (CAIS) . Journal of Human Lactation vol. 36 , ( 4 ) 791 - 794 .
Pittaway JFH, Harrison C, Rhee Y, Holder-Espinasse M, Fryer AE, Cundy T, Drake WM, Irving MD ( 2019 ) . Correction to: Bisphosphonate therapy for spinal osteoporosis in Hajdu-Cheney syndrome – new data and literature review . vol. 14 , is. 1 , Springer Nature
Chowdhury TA, Khan H, Druce MR, Drake WM, Rajakariar R, Thuraisingham R, Dobbie H, Parvanta L et al. ( 2019 ) . Flipped learning: Turning medical education upside down . Future Healthcare Journal vol. 6 , ( 3 ) 192 - 195 .
Hadjidemetriou I, Mariniello K, Ruiz-Babot G, Pittaway J, Mancini A, Mariannis D, Gomez-Sanchez CE, Parvanta L et al. ( 2019 ) . DLK1/PREF1 marks a novel cell population in the human adrenal cortex . The Journal of Steroid Biochemistry and Molecular Biology vol. 193 ,
Jacob P, Dow C, Lasker SS, Drake WM, Chowdhury TA ( 2019 ) . Hyponatraemia in primary care . The BMJ vol. 365 ,
Tufton N, White G, Drake WM, Sahdev A, Akker SA ( 2019 ) . Diffusion‐weighted imaging (DWI) highlights SDHB‐related tumours: A pilot study . Clinical Endocrinology vol. 91 , ( 1 ) 104 - 109 .
Lim ES, Shah SG, Waterhouse M, Akker S, Drake W, Plowman N, Berney DM, Richards P et al. ( 2019 ) . Impact of thyroiditis on 131I uptake during ablative therapy for differentiated thyroid cancer . Endocrine Connections vol. 8 , ( 5 ) 454 - 461 .
Steeds R, Stiles C, Sharma V, Chambers J, Lloyd G, Drake W ( 2019 ) . Echocardiography and monitoring patients receiving dopamine agonist therapy for hyperprolactinaemia: A joint position statement of the British Society of Echocardiography, the British Heart Valve Society and the Society for Endocrinology . Clinical Endocrinology vol. 90 , ( 5 ) 662 - 669 .
Tshuma N, Glynn N, Evanson J, Powles T, Drake WM ( 2018 ) . Hypothalamitis and severe hypothalamic dysfunction associated with anti–programmed cell death ligand 1 antibody treatment . European Journal of Cancer vol. 104 , 247 - 249 .
Wilkinson IC, Riddoch F, Perry LA, Martin L, Grossman AB, Monson JP, Akker S, Savage MO et al. . New insights into the low dose dexamethasone suppression test in paediatric Cushing's syndrome (CS) . Endocrine Abstracts .
O’Toole SM, Watson DS, Novoselova TV, Romano LEL, King PJ, Bradshaw TY, Thompson CL, Knight MM et al. ( 2018 ) . Oncometabolite induced primary cilia loss in pheochromocytoma . Endocrine Related Cancer vol. 26 , ( 1 ) 165 - 180 .
O'Toole SM, Sahdev A, Bhattacharya S, Feakins R, Gevers EF, Drake WM ( 2018 ) . Paediatric pancreatic neuroendocrine tumours in von Hippel–Lindau disease . Endocrine Related Cancer vol. 25 , ( 9 ) l43 - l47 .
Pittaway JFH, Harrison C, Rhee Y, Holder-Espinasse M, Fryer AE, Cundy T, Drake WM, Irving MD ( 2018 ) . Bisphosphonate therapy for spinal osteoporosis in Hajdu-Cheney syndrome – new data and literature review . Orphanet Journal of Rare Diseases vol. 13 , ( 1 )
Ruiz-Babot G, Balyura M, Hadjidemetriou I, Ajodha SJ, Taylor DR, Ghataore L, Taylor NF, Schubert U et al. ( 2018 ) . Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells . Cell Reports vol. 22 , ( 5 ) 1236 - 1249 .
O'Toole SM, Drake WM ( 2017 ) . Response to Somatostatin Analog Therapy in a Patient With von Hippel-Lindau Disease and Multiple Pancreatic Neuroendocrine Tumors . Pancreas vol. 46 , ( 7 )
Hussain S, Hallam S, Beltran L, Haroon A, Majumdar K, Shamash J, Sivapackianathan R, Drake W ( 2017 ) . Intravascular large B‐cell lymphoma presenting as a pituitary mass with bilateral adrenal enlargement and haemophagocytic lymphohistiocytosis . British Journal of Haematology vol. 181 , ( 6 ) 851 - 852 .
Tufton N, Gunganah K, Hussain S, Druce M, Carpenter R, Ashby M, Drake WM, Akker SA ( 2017 ) . Alpha blockade—not to be underdone . vol. 86 , is. 2 , pp. 306 - 308 . Wiley
Srirangalingam U, LeCain M, Tufton N, Akker SA, Drake WM, Metcalfe K ( 2016 ) . Four generations of SDHB-related disease: complexities in management . Familial Cancer vol. 16 , ( 2 ) 279 - 282 .
Tufton N, Shapiro L, Srirangalingam U, Richards P, Sahdev A, Kumar AV, McAndrew L, Martin L et al. ( 2016 ) . Outcomes of annual surveillance imaging in an adult and paediatric cohort of succinate dehydrogenase B mutation carriers . Clinical Endocrinology vol. 86 , ( 2 ) 286 - 296 .
Baldeweg SE, Vanderpump M, Drake W, Reddy N, Markey A, Plant GT, Powell M, Sinha S et al. ( 2016 ) . SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of pituitary apoplexy in adult patients . Endocrine Connections vol. 5 , ( 5 ) g12 - g15 .
Brown MJ, Drake WM ( 2016 ) . Splitting atoms: the Endocrine Society guideline for the management of primary aldosteronism . The Lancet Diabetes & Endocrinology vol. 4 , ( 10 ) 805 - 807 .
Srirangalingam U, Banerjee A, Patki P, Peters J, George E, Chew SL, Kumar VKA, Korbonits M et al. ( 2016 ) . Succinate Dehydrogenase B (SDHB)-Associated Bladder Paragangliomas . Clinical Genitourinary Cancer vol. 15 , ( 1 ) e131 - e136 .
Shapiro L, Elahi S, Riddoch F, Perry LA, Martin L, Akker SA, Monson JP, Drake WM et al. ( 2016 ) . Investigation for Paediatric Cushing's Syndrome Using Twenty-Four-Hour Urinary Free Cortisol Determination . Horm Res Paediatr vol. 86 , ( 1 ) 21 - 26 .
Chung TT, Gunganah K, Monson JP, Drake WM ( 2016 ) . Circadian variation in serum cortisol during hydrocortisone replacement is not attributable to changes in cortisol‐binding globulin concentrations . Clinical Endocrinology vol. 84 , ( 4 ) 496 - 500 .
Gunganah K, Carpenter R, Drake WM ( 2015 ) . Eplerenone use in primary aldosteronism during pregnancy . Clinical Case Reports vol. 4 , ( 1 ) 81 - 82 .
Mownah OA, Pafitanis G, Drake WM, Crinnion JN ( 2015 ) . Contemporary surgical treatment of primary hyperparathyroidism without intraoperative parathyroid hormone measurement . Annals of The Royal College of Surgeons of England vol. 97 , ( 8 ) 603 - 607 .
Sze WCC, McQuillan J, Plowman PN, MacDougall N, Blackburn P, Sabin HI, Ali N, Drake WM ( 2015 ) . Stereotactic radiosurgery XX: ocular neuromyotonia in association with gamma knife radiosurgery . Endocrinology Diabetes and Metabolism Case Reports vol. 2015 , ( 1 )
Hussain S, Panteliou E, Berney DM, Carpenter R, Matson M, Sahdev A, Bell M, O'Sullivan E et al. ( 2015 ) . Pure aldosterone-secreting adrenocortical carcinoma in a patient with refractory primary hyperaldosteronism . Endocrinology Diabetes and Metabolism Case Reports vol. 2015 , ( 1 )
Corrigall D, Ziolkowski B, Woodland P, Hannon M, ChinAleong J, Jenkins P, Fairclough P, Drake W et al. ( 2015 ) . PWE-351 Acromegaly and colonic polyps revisited: time to change the guidelines? . Gut . vol. 64 ,
Dénes J, Swords F, Rattenberry E, Stals K, Owens M, Cranston T, Xekouki P, Moran L et al. ( 2014 ) . Heterogeneous Genetic Background of the Association of Pheochromocytoma/Paraganglioma and Pituitary Adenoma: Results From a Large Patient Cohort . The Journal of Clinical Endocrinology & Metabolism vol. 100 , ( 3 ) e531 - e541 .
Sivapackianathan R, Parker A, Carpenter R, Achan P, Rastogi A, Sarkodieh J, Drake WM ( 2014 ) . Profound vitamin D deficiency in coeliac disease and pregnancy . QJM vol. 108 , ( 4 ) 345 - 346 .
Nadarasa K, Theodoraki A, Kurzawinski TR, Carpenter R, Bull J, Chung TT, Drake WM ( 2014 ) . Denosumab for management of refractory hypercalcaemia in recurrent parathyroid carcinoma . European Journal of Endocrinology vol. 171 , ( 3 ) l7 - l8 .
Gupta PS, Grozinsky-Glasberg S, Drake WM, Akker SA, Perry L, Grossman AB, Druce MR ( 2014 ) . Are serotonin metabolite levels related to bone mineral density in patients with neuroendocrine tumours? . Clinical Endocrinology vol. 80 , ( 2 ) 246 - 252 .
Drake WM, Stiles CE, Howlett TA, Toogood AA, Bevan JS, Steeds RP, Group OBOTUDAV ( 2013 ) . A Cross-Sectional Study of the Prevalence of Cardiac Valvular Abnormalities in Hyperprolactinemic Patients Treated With Ergot-Derived Dopamine Agonists . The Journal of Clinical Endocrinology & Metabolism vol. 99 , ( 1 ) 90 - 96 .
Cavlan D, Vijayaraghavan S, Gelding S, Drake W ( 2013 ) . GH replacement causing acute hyperglycaemia and ketonuria in a type 1 diabetic patient . Endocrinology Diabetes and Metabolism Case Reports vol. 2013 , ( 1 )
Sze WCC, Grossman AB, Goddard I, Amendra D, Shieh SCC, Plowman PN, Drake WM, Akker SA et al. ( 2013 ) . Sequelae and survivorship in patients treated with 131I-MIBG therapy . British Journal of Cancer vol. 109 , ( 3 ) 565 - 572 .
Alexandraki KI, Kaltsas GA, Isidori AM, Storr HL, Afshar F, Sabin I, Akker SA, Chew SL et al. ( 2013 ) . Long-term remission and recurrence rates in Cushing's disease: predictive factors in a single-centre study . European Journal of Endocrinology vol. 168 , ( 4 ) 639 - 648 .
Khan K, Drake, Akker S, White V ( 2012 ) . P50 Pituitary Granulomata - TB or Not TB . Thorax . vol. 67 ,
Sehgal V, Vijayan S, Yasmin S, Srirangalingam U, Pati J, Drake ( 2011 ) . Normocalcaemic tetany . Clinical Medicine vol. 11 , ( 6 ) 594 - 595 .
Bharwani N, Rockall AG, Sahdev A, Gueorguiev M, Drake W, Grossman AB, Reznek RH ( 2011 ) . Adrenocortical carcinoma: the range of appearances on CT and MRI . American Journal of Roentgenology vol. 196 , ( 6 ) w706 - w714 .
Simpson MA, Irving MD, Asilmaz E, Gray MJ, Dafou D, Elmslie FV, Mansour S, Holder SE et al. ( 2011 ) . Mutations in NOTCH2 cause Hajdu-Cheney syndrome, a disorder of severe and progressive bone loss . Nature Genetics vol. 43 , ( 4 ) 303 - 305 .
Druce MR, Walker D, Maher KT, Dodzo K, Perry L, Ball S, Peaston R, Chew SL et al. ( 2011 ) . The Effect of Exogenous Glucocorticoids on Plasma Catecholamines and Metanephrines in Patients Without Phaeochromocytomas . Hormone and Metabolic Research vol. 43 , ( 04 ) 292 - 295 .
Rajasekaran S, Vanderpump M, Baldeweg S, Drake W, Reddy N, Lanyon M, Markey A, Plant G et al. ( 2010 ) . UK guidelines for the management of pituitary apoplexy . Clinical Endocrinology vol. 74 , ( 1 ) 9 - 20 .
Salehi F, Scheithauer BW, Moyes VJ, Drake WM, Syro LV, Manoranjan B, Sharma S, Horvath E et al. ( 2010 ) . Low Immunohistochemical Expression of MGMT in ACTH Secreting Pituitary Tumors of Patients with Nelson Syndrome . Endocrine Pathology vol. 21 , ( 4 ) 227 - 229 .
Chung TTLL, Drake WM, Plowman PN, Metcalfe K, Grossman AB, Akker SA, Chew SL, Besser GM et al. ( 2010 ) . No clear evidence for an association between GH replacement and relapse of intracranial germ cell tumours: single centre and KIMS experience . European Journal of Endocrinology vol. 163 , ( 2 ) 357 - 358 .
Misra S, Johnston LB, Drake WM ( 2010 ) . Severe hypernatraemia associated with growth hormone replacement therapy in a patient with septo-optic dysplasia . Pituitary vol. 13 , ( 2 ) 186 - 188 .
Igreja S, Chahal HS, King P, Bolger GB, Srirangalingam U, Guasti L, Chapple JP, Trivellin G et al. ( 2010 ) . Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families . Human Mutation vol. 31 , ( 8 ) 950 - 960 .
Dworakowska D, Gueorguiev M, Kelly P, Monson JP, Besser GM, Chew SL, Akker SA, Drake WM et al. ( 2010 ) . Repeated colonoscopic screening of patients with acromegaly: 15-year experience identifies those at risk of new colonic neoplasia and allows for effective screening guidelines . European Journal of Endocrinology vol. 163 , ( 1 ) 21 - 28 .
Barwick T, Murray I, Megadmi H, Drake WM, Plowman PN, Akker SA, Chew SL, Grossman AB et al. ( 2010 ) . Single photon emission computed tomography (SPECT)/computed tomography using Iodine-123 in patients with differentiated thyroid cancer: additional value over whole body planar imaging and SPECT . European Journal of Endocrinology vol. 162 , ( 6 ) 1131 - 1139 .
Ananth S, Cheng L, Anderson J, Drake W, Rowe S, Burke S, Richards P, Offiah C et al. ( 2009 ) . Parathyroid surgery—a local survey . British Journal of Oral and Maxillofacial Surgery vol. 47 , ( 7 )
Procopiou M, Finney H, Akker SA, Chew SL, Drake WM, Burrin J, Grossman AB ( 2009 ) . Evaluation of an enzyme immunoassay for plasma-free metanephrines in the diagnosis of catecholamine-secreting tumors . European Journal of Endocrinology vol. 161 , ( 3 ) 509 - 509 .
Higham CE, Chung TT, Lawrance J, Drake WM, Trainer PJ ( 2009 ) . Long‐term experience of pegvisomant therapy as a treatment for acromegaly . Clinical Endocrinology vol. 71 , ( 1 ) 86 - 91 .
Higham CE, Thomas JDJ, Bidlingmaier M, Drake WM, Trainer PJ ( 2009 ) . Successful use of weekly pegvisomant administration in patients with acromegaly . European Journal of Endocrinology vol. 161 , ( 1 ) 21 - 25 .
Procopiou M, Finney H, Akker SA, Chew SL, Drake WM, Burrin J, Grossman AB ( 2009 ) . Evaluation of an enzyme immunoassay for plasma-free metanephrines in the diagnosis of catecholamine-secreting tumors . European Journal of Endocrinology vol. 161 , ( 1 ) 131 - 140 .
Alexandraki KI, Kaltsas GA, Isidori AM, Akker SA, Drake WM, Chew SL, Monson JP, Besser GM et al. ( 2009 ) . The prevalence and characteristic features of cyclicity and variability in Cushing's disease . European Journal of Endocrinology vol. 160 , ( 6 ) 1011 - 1018 .
Srirangalingam U, Khoo B, Walker L, MacDonald F, Skelly RH, George E, Spooner D, Johnston LB et al. ( 2009 ) . Contrasting clinical manifestations of SDHB and VHL associated chromaffin tumours . Endocrine Related Cancer vol. 16 , ( 2 ) 515 - 525 .
Moyes VJ, Alusi G, Sabin HI, Evanson J, Berney DM, Kovacs K, Monson JP, Plowman PN et al. ( 2008 ) . Treatment of Nelson's syndrome with temozolomide . European Journal of Endocrinology vol. 160 , ( 1 ) 115 - 119 .
Moyes VJ, Metcalfe KA, Drake WM ( 2008 ) . Clinical use of cabergoline as primary and adjunctive treatment for acromegaly . EUR J ENDOCRINOL vol. 159 , ( 5 ) 541 - 545 .
Jimenez C, Burman P, Abs R, Clemmons DR, Drake WM, Hutson KR, Messig M, Thorner MO et al. ( 2008 ) . Follow-up of pituitary tumor volume in patients with acromegaly treated with pegvisomant in clinical trials . European Journal of Endocrinology vol. 159 , ( 5 ) 517 - 523 .
Chung TT, Evanson J, Walker D, Akker SA, Besser GM, Monson JP, Grossman AB, Drake WM ( 2008 ) . Safety of GH replacement in hypopituitary patients with nonirradiated pituitary and peripituitary tumours . Clin Endocrinol (Oxf) vol. 68 , ( 6 ) 965 - 969 .
Colson A, Walker D, Besser GM, Grossman AB, Chew SL, Jenkins PJ, Drake WM, Monson JP ( 2008 ) . Role of fasting plasma glucose, glycated haemoglobin and homeostatic model assessment in the detection of glucose intolerance in adult hypopituitary patients during growth hormone replacement therapy . HORM RES vol. 69 , ( 2 ) 83 - 88 .
Coyle FM, Taylor NF, Monson JP, Drake WM, Foster GR ( 2007 ) . Non-alcoholic fatty liver disease is associated with transcriptional dysregulation of the corticosteroid metabolising enzyme II beta HSD-1 leading to excess intrahepatic steroid exposure . HEPATOLOGY . vol. 46 , 741A - 741A .
Brooke AM, Drake WM ( 2007 ) . Serum IGF-I levels in the diagnosis and monitoring of acromegaly . PITUITARY vol. 10 , ( 2 ) 173 - 179 .
Peters CJ, Nugent T, Perry LA, Davies K, Morel Y, Drake WM, Savage MO, Johnston LB ( 2007 ) . Cosegregation of a novel homozygous CYP11B1 mutation with the phenotype of non-classical congenital adrenal hyperplasia in a consanguineous family . HORM RES vol. 67 , ( 4 ) 189 - 193 .
Chahal HS, Drake WM ( 2007 ) . The endocrine system and ageing . J PATHOL vol. 211 , ( 2 ) 173 - 180 .
Agha A, Walker D, Perry L, Drake WM, Chew SL, Jenkins PJ, Grossman AB, Monson JP ( 2007 ) . Unmasking of central hypothyroidism following growth hormone replacement in adult hypopituitary patients . Clin Endocrinol (Oxf) vol. 66 , ( 1 ) 72 - 77 .
Ogilvie CM, Brown PL, Matson M, Dacie J, Reznek RH, Britton K, Carpenter R, Berney D et al. ( 2006 ) . Selective parathyroid venous sampling in patients with complicated hyperparathyroidism . EUR J ENDOCRINOL vol. 155 , ( 6 ) 813 - 821 .
Paisley AN, O'Callaghan CJ, Lewandowski KC, Parkinson C, Roberts ME, Drake WM, Monson JP, Trainer PJ et al. ( 2006 ) . Reductions of circulating matrix metalloproteinase 2 and vascular endothelial growth factor levels after treatment with pegvisomant in subjects with acromegaly . J CLIN ENDOCR METAB vol. 91 , ( 11 ) 4635 - 4640 .
Ali N, Sebastian C, Foley RR, Murray I, Canizales AL, Jenkins PJ, Drake WM, Plowman PN et al. ( 2006 ) . The management of differentiated thyroid cancer using I-123 for imaging to assess the need for I-131 therapy . NUCL MED COMMUN vol. 27 , ( 2 ) 165 - 169 .
Priesemann M, Davies KM, Perry LA, Drake WM, Chew SL, Monson JP, Savage MO, Johnston LB ( 2006 ) . Benefits of screening in von Hippel-Lindau disease--comparison of morbidity associated with initial tumours in affected parents and children . Horm Res vol. 66 , ( 1 ) 1 - 5 .
Colson A, Brooke AM, Walker D, Besser GM, Chew SL, Grossman AB, Jenkins PJ, Drake WM et al. ( 2006 ) . Growth hormone deficiency and replacement in patients with treated Cushing's Disease, prolactinomas and non-functioning pituitary adenomas: effects on body composition, glucose metabolism, lipid status and bone mineral density . Horm Res vol. 66 , ( 6 ) 257 - 267 .
Barkan AL, Burman P, Clemmons DR, Drake WM, Gagel RF, Harris PE, Trainer PJ, van der Lely AJ et al. ( 2005 ) . Glucose homeostasis and safety in patients with acromegaly converted from long-acting octreotide to pegvisomant . J CLIN ENDOCR METAB vol. 90 , ( 10 ) 5684 - 5691 .
Chung TT, Drake WM, Evanson J, Walker D, Plowman PN, Chew SL, Grossman AB, Besser GM et al. ( 2005 ) . Tumour surveillance imaging in patients with extrapituitary tumours receiving growth hormone replacement . CLIN ENDOCRINOL vol. 63 , ( 3 ) 274 - 279 .
Drake WM, Berney DM, Kovacs K, Monson JP ( 2005 ) . Markers of cell proliferation in a GH-producing adenoma of a patient treated with pegvisomant . EUR J ENDOCRINOL vol. 153 , ( 2 ) 203 - 205 .
Drake WM, Loureiro RA, Parkinson C, Monson JP, Besser GM, Trainer PJ ( 2005 ) . Disease activity in acromegaly may be assessed 6 weeks after discontinuation of pegvisomant . Eur J Endocrinol vol. 152 , ( 1 ) 47 - 51 .
Drake WM, Grossman AB, Hutson RK ( 2005 ) . Effect of treatment with pegvisomant on meningioma growth in vivo . EUR J ENDOCRINOL vol. 152 , ( 1 ) 161 - 162 .
Carroll PV, Drake WM, Maher KT, Metcalfe K, Shaw NJ, Dunger DB, Cheetham TD, Camacho-Hübner C et al. ( 2004 ) . Comparison of continuation or cessation of growth hormone (GH) therapy on body composition and metabolic status in adolescents with severe GH deficiency at completion of linear growth . J Clin Endocrinol Metab vol. 89 , ( 8 ) 3890 - 3895 .
Savage MO, Drake WM, Carroll PV, Monson JP ( 2004 ) . Transitional care of GH deficiency: when to stop GH therapy . EUR J ENDOCRINOL vol. 151 , S61 - S65 .
Paisley AN, Trainer PJ, Drake WM ( 2004 ) . The place of pegvisomant in the acromegaly treatment algorithm . GROWTH HORMONE & IGF RESEARCH . vol. 14 , S101 - S106 .
Drake WM, Kendler DL, Rosen CJ, Orwoll ES ( 2003 ) . An investigation of the predictors of bone mineral density and response to therapy with alendronate in osteoporotic men . J Clin Endocrinol Metab vol. 88 , ( 12 ) 5759 - 5765 .
Drake WM, Rowles SV, Roberts ME, Fode FK, Besser GM, Monson JP, Trainer PJ ( 2003 ) . Insulin sensitivity and glucose tolerance improve in patients with acromegaly converted from depot octreotide to pegvisomant . Eur J Endocrinol vol. 149 , ( 6 ) 521 - 527 .
Jenkins PJ, Satta MA, Simmgen M, Drake WM, Williamson C, Lowe DG, Britton K, Chew SL et al. ( 2003 ) . Metastatic parathyroid carcinoma in the MEN2A syndrome . Clinical Endocrinology vol. 47 , ( 6 ) 747 - 751 .
Drake WM, Carroll PV, Maher KT, Metcalfe KA, Camacho-Hubner C, Shaw NJ, Dunger DB, Cheetham TD et al. ( 2003 ) . The effect of cessation of growth hormone (GH) therapy on bone mineral accretion in GH-deficient adolescents at the completion of linear growth - Response . J CLIN ENDOCR METAB vol. 88 , ( 9 ) 4506 - 4507 .
Parkinson C, Whatmore AJ, Yates AP, Drake WM, Brabant G, Clayton PE, Trainer PJ ( 2003 ) . The effect of pegvisomant-induced serum IGF-I normalization on serum leptin levels in patients with acromegaly . CLIN ENDOCRINOL vol. 59 , ( 2 ) 168 - 174 .
Drake WM, Carroll PV, Maher KT, Metcalfe KA, Camacho-Hübner C, Shaw NJ, Dunger DB, Cheetham TD et al. ( 2003 ) . The effect of cessation of growth hormone (GH) therapy on bone mineral accretion in GH-deficient adolescents at the completion of linear growth . J Clin Endocrinol Metab vol. 88 , ( 4 ) 1658 - 1663 .
Drake WM, Hiorns MP, Kendler DL ( 2003 ) . Hadju-Cheney syndrome: Response to therapy with bisphosphonates in two patients . J BONE MINER RES vol. 18 , ( 1 ) 131 - 133 .
Drake WM, Carroll PV, Savage MO, Monson JP ( 2002 ) . Skeletal consequences of discontinuation of growth hormone at final height . JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM . vol. 15 , 1351 - 1354 .
Parkinson C, Drake WM, Roberts ME, Meeran K, Besser GM, Trainer PJ ( 2002 ) . A comparison of the effects of pegvisomant and octreotide on glucose, insulin, gastrin, cholecystokinin and pancreatic polypeptide responses to oral glucose and a standard mixed meal . J CLIN ENDOCR METAB vol. 87 , ( 4 ) 1797 - 1804 .
Newell-Price J, Morris DG, Drake WM, Korbonits M, Monson JP, Besser GM, Grossman AB ( 2002 ) . Optimal response criteria for the human CRH test in the differential diagnosis of ACTH-dependent Cushing's syndrome . J CLIN ENDOCR METAB vol. 87 , ( 4 ) 1640 - 1645 .
Parkinson C, Drake WM, Wieringa G, Yates AP, Besser GM, Trainer PJ ( 2002 ) . Serum lipoprotein changes following IGF-I normalization using a growth hormone receptor antagonist in acromegaly . CLIN ENDOCRINOL vol. 56 , ( 3 ) 303 - 311 .
Monson JP, Drake WM, Carroll PV, Weaver JU, Rodriquez-Arnao J, Savage MO ( 2002 ) . Influence of growth hormone on accretion of bone mass . HORMONE RESEARCH . vol. 58 , 52 - 56 .
Drake WM, Brown JP, Banville C, Kendler DL ( 2002 ) . Use of phalangeal bone mineral density and multi-site speed of sound conduction to monitor therapy with alendronate in postmenopausal women . OSTEOPOROSIS INT vol. 13 , ( 3 ) 249 - 256 .
Drake WM, Parkinson C, Besser GM, Trainer PJ ( 2001 ) . Clinical use a of growth hormone receptor antagonist in the treatment of acromegaly . TRENDS ENDOCRIN MET vol. 12 , ( 9 ) 408 - 413 .
Frajese G, Drake WM, Loureiro RA, Evanson J, Coyte D, Wood DF, Grossman AB, Besser GM et al. ( 2001 ) . Hypothalamo-pituitary surveillance imaging in hypopituitary patients receiving long-term GH replacement therapy . J Clin Endocrinol Metab vol. 86 , ( 11 ) 5172 - 5175 .
Drake WM, Parkinson C, Akker SA, Monson JP, Besser GM, Trainer PJ ( 2001 ) . Successful treatment of resistant acromegaly with a growth hormone receptor antagonist . EUR J ENDOCRINOL vol. 145 , ( 4 ) 451 - 456 .
Drake WM, Howell SJ, Monson JP, Shalet SM ( 2001 ) . Optimizing gh therapy in adults and children . Endocr Rev vol. 22 , ( 4 ) 425 - 450 .
Trainer PJ, Drake WM, Perry LA, Taylor NF, Besser GM, Monson JP ( 2001 ) . Modulation of cortisol metabolism by the growth hormone receptor antagonist pegvisomant in patients with acromegaly . J CLIN ENDOCR METAB vol. 86 , ( 7 ) 2989 - 2992 .
Drake WM, Rodriguez-Arnao J, Weaver JU, James IT, Coyte D, Spector TD, Besser GM, Monson JP ( 2001 ) . The influence of gender on the short and long-term effects of growth hormone replacement on bone metabolism and bone mineral density in hypopituitary adults: a 5-year study . CLIN ENDOCRINOL vol. 54 , ( 4 ) 525 - 532 .
Drake WM, Lowe SR, Mirtella A, Bartlett TJ, Clark AJ ( 2000 ) . Desensitisation of calcitonin gene-related peptide responsiveness but not adrenomedullin responsiveness in vascular smooth muscle cells . Journal of Endocrinology vol. 165 , ( 1 ) 133 - 138 .
Drake WM, Ajayi A, Lowe SR, Mirtella A, Bartlett TJ, Clark AJL ( 1999 ) . Desensitization of CGRP and adrenomedullin receptors in SK-N-MC cells: implications for the RAMP hypothesis . Endocrinology vol. 140 , ( 1 ) 533 - 537 .
Drake WM, Perry LA, Hinds CJ, Lowe DG, Reznek RH, Besser GM ( 1998 ) . Emergency and prolonged use of intravenous etomidate to control hypercortisolemia in a patient with Cushing's syndrome and peritonitis . The Journal of Clinical Endocrinology & Metabolism vol. 83 , ( 10 ) 3542 - 3544 .
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