Publications: Dr Adrian Biddle
Sahoo S, Ashraf B, Duddu AS, Biddle A, Jolly MK
(
2022
)
.
Interconnected high-dimensional landscapes of epithelial–mesenchymal plasticity and stemness in cancer
.
Clinical and Experimental Metastasis
Custódio M, Biddle A, Tavassoli M
(
2020
)
.
Portrait of a CAF: The story of cancer-associated fibroblasts in head and neck cancer
.
Oral Oncology
vol.
110
,
Youssef G, Cottoms H, Piper K, Gammon L, Knowles O, Lunt SA, Mackenzie I, Philpott M et al.
(
2019
)
.
585 Identifying cancer stem cells in patient specimens through high-content imaging - biological insights and prognostic potential
.
Journal of Investigative Dermatology
.
vol.
139
,
Jolly MK, Somarelli JA, Sheth M, Biddle A, Tripathi SC, Armstrong AJ, Hanash SM, Bapat SA et al.
(
2019
)
.
Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas
.
Pharmacology and Therapeutics
vol.
194
,
161
-
184
.
Knowles O, Doldan P, Hillier-Richardson I, Lunt S, Gammon L, Youssef G, Harwood C, Mackenzie I et al.
(
2018
)
.
Identification of a novel cancer stem cell subpopulation in melanoma pathological specimens
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
178
,
E411
-
E411
.
MACKENZIE IC, Rodrigues MF, Gammon L, RAHMAN M, BIDDLE A, Nunes FD
(
2018
)
.
Effects of Cetuximab and Erlotinib on the behaviour of cancer stem cells in head and neck squamous cell carcinoma
.
Oncotarget
O'Brien-Ball C, Biddle A
(
2017
)
.
Reprogramming to developmental plasticity in cancer stem cells
.
Developmental Biology
vol.
430
,
(
2
)
266
-
274
.
Vig NK, Gammon L, Peyric E, Rahman M, Biddle A, Mackenzie IC
(
2017
)
.
The amoeboid cell in cancer
.
BRITISH JOURNAL OF SURGERY
.
vol.
104
,
43
-
43
.
BIDDLE A, Gammon L, Liang X, Costea DE, Mackenzie IC
(
2016
)
.
Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma
.
EBioMedicine
Vig N, Mackenzie IC, Biddle A
(
2015
)
.
Phenotypic plasticity and epithelial-to-mesenchymal transition in the behaviour and therapeutic response of oral squamous cell carcinoma
.
Journal of Oral Pathology and Medicine
vol.
44
,
(
9
)
649
-
655
.
Shigeishi H, Biddle A, Gammon L, Rodini CO, Yamasaki M, Seino S, Sugiyama M, Takechi M et al.
(
2015
)
.
Elevation in 5-FU-induced apoptosis in head and neck cancer stem cells by a combination of CDHP and GSK3β inhibitors
.
J Oral Pathol Med
vol.
44
,
(
3
)
201
-
207
.
Gemenetzidis E, Gammon L, Biddle A, Emich H, Mackenzie IC
(
2015
)
.
Invasive oral cancer stem cells display resistance to ionising radiation
.
Oncotarget
vol.
6
,
(
41
)
43964
-
43977
.
Hufbauer M, Biddle A, Borgogna C, Gariglio M, Doorbar J, Storey A, Pfister H, Mackenzie I et al.
(
2013
)
.
Expression of Betapapillomavirus Oncogenes Increases the Number of Keratinocytes with Stem Cell-Like Properties
.
JOURNAL OF VIROLOGY
vol.
87
,
(
22
)
12158
-
12165
.
Shigeishi H, Biddle A, Gammon L, Emich H, Rodini CO, Gemenetzidis E, Fazil B, Sugiyama M et al.
(
2013
)
.
Maintenance of stem cell self-renewal in head and neck cancers requires actions of GSK3β influenced by CD44 and RHAMM
.
Stem Cells
vol.
31
,
(
10
)
2073
-
2083
.
Biddle A, Gammon L, Fazil B, Mackenzie IC
(
2013
)
.
CD44 staining of cancer stem-like cells is influenced by down-regulation of CD44 variant isoforms and up-regulation of the standard CD44 isoform in the population of cells that have undergone epithelial-to-mesenchymal transition
.
PLoS One
vol.
8
,
(
2
)
Gammon L, Biddle A, Heywood HK, Johannessen AC, Mackenzie IC
(
2013
)
.
Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism
.
PLoS One
vol.
8
,
(
4
)
Biddle A, Mackenzie IC
(
2012
)
.
Cancer stem cells and EMT in carcinoma
.
Cancer Metastasis Rev
VALORANI MG, Montelatici E, Germani A, Biddle A, D'Alessandro D, Strollo R, Patrizi MP, Lazzari L et al.
(
2012
)
.
Pre-culturing human adipose tissue mesenchymal stem cells under hypoxia increases their adipogenic and osteogenic differentiation potential
.
Cell Proliferation
vol.
45
,
(
3
)
225
-
238
.
Biddle A, Liang X, Gammon L, Fazil B, Harper LJ, Emich H, Costea DE, Mackenzie IC
(
2011
)
.
Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative
.
Cancer Res
vol.
71
,
(
15
)
5317
-
5326
.
Gammon L, Biddle A, Fazil B, Harper L, Mackenzie IC
(
2011
)
.
Stem cell characteristics of cell sub-populations in cell lines derived from head and neck cancers of Fanconi anemia patients
.
J Oral Pathol Med
vol.
40
,
(
2
)
143
-
152
.
Valorani MG, Germani A, Otto WR, Harper L, Biddle A, Khoo CP, Lin WR, Hawa MI et al.
(
2010
)
.
Hypoxia increases Sca-1/CD44 co-expression in murine mesenchymal stem cells and enhances their adipogenic differentiation potential
.
Cell Tissue Res
vol.
341
,
(
1
)
111
-
120
.
Harper LJ, Costea DE, Gammon L, Fazil B, Biddle A, Mackenzie IC
(
2010
)
.
Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance
.
BMC Cancer
vol.
10
,
Biddle A, Simeoni I, Gurdon JB
(
2009
)
.
Xenopus oocytes reactivate muscle gene transcription in transplanted somatic nuclei independently of myogenic factors
.
DEVELOPMENT
vol.
136
,
(
16
)
2695
-
2703
.
Dragnev KH, Petty WJ, Shah S, Biddle A, Desai NB, Memoli V, Rigas JR, Dmitrovsky E
(
2005
)
.
Bexarotene and erlotinib for aerodigestive tract cancer
.
Journal of Clinical Oncology
vol.
23
,
(
34
)
8757
-
8764
.
Petty WJ, Li N, Biddle A, Bounds R, Nitkin C, Ma Y, Dragnev KH, Freemantle SJ et al.
(
2005
)
.
A novel retinoic acid receptor β isoform and retinoid resistance in lung carcinogenesis
.
Journal of the National Cancer Institute
vol.
97
,
(
22
)
1645
-
1651
.
Petty WJ, Bragnev KH, Memoli VA, Ma Y, Desai NB, Biddle A, Davis TH, Nugent WC et al.
(
2004
)
.
Epidermal growth factor receptor tyrosine kinase inhibition represses cyclin D1 in aerodigestive tract cancers
.
Clinical Cancer Research
vol.
10
,
(
22
)
7547
-
7554
.