Marles H, Biddle A ( 2022 ) . Cancer stem cell plasticity and its implications in the development of new clinical approaches for oral squamous cell carcinoma . Biochemical Pharmacology vol. 204 ,
Scemama A, Lunetto S, Biddle A ( 2022 ) . Highlight: microfluidic devices for cancer metastasis studies . In vitro models1 - 5 .
Sahoo S, Ashraf B, Duddu AS, Biddle A, Jolly MK ( 2022 ) . Interconnected high-dimensional landscapes of epithelial–mesenchymal plasticity and stemness in cancer . Clinical and Experimental Metastasis vol. 39 , ( 2 ) 279 - 290 .
Custódio M, Biddle A, Tavassoli M ( 2020 ) . Portrait of a CAF: The story of cancer-associated fibroblasts in head and neck cancer . Oral Oncology vol. 110 ,
Youssef G, Cottoms H, Piper K, Gammon L, Knowles O, Lunt SA, Mackenzie I, Philpott M et al. ( 2019 ) . 585 Identifying cancer stem cells in patient specimens through high-content imaging - biological insights and prognostic potential . Journal of Investigative Dermatology . vol. 139 ,
Jolly MK, Somarelli JA, Sheth M, Biddle A, Tripathi SC, Armstrong AJ, Hanash SM, Bapat SA et al. ( 2019 ) . Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas . Pharmacology and Therapeutics vol. 194 , 161 - 184 .
Knowles O, Doldan P, Hillier-Richardson I, Lunt S, Gammon L, Youssef G, Harwood C, Mackenzie I et al. ( 2018 ) . Identification of a novel cancer stem cell subpopulation in melanoma pathological specimens . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E411 - E411 .
MACKENZIE IC, Rodrigues MF, Gammon L, RAHMAN M, BIDDLE A, Nunes FD ( 2018 ) . Effects of Cetuximab and Erlotinib on the behaviour of cancer stem cells in head and neck squamous cell carcinoma . Oncotarget
O'Brien-Ball C, Biddle A ( 2017 ) . Reprogramming to developmental plasticity in cancer stem cells . Developmental Biology vol. 430 , ( 2 ) 266 - 274 .
Vig NK, Gammon L, Peyric E, Rahman M, Biddle A, Mackenzie IC ( 2017 ) . The amoeboid cell in cancer . BRITISH JOURNAL OF SURGERY . vol. 104 , 43 - 43 .
BIDDLE A, Gammon L, Liang X, Costea DE, Mackenzie IC ( 2016 ) . Phenotypic Plasticity Determines Cancer Stem Cell Therapeutic Resistance in Oral Squamous Cell Carcinoma . EBioMedicine
Vig N, Mackenzie IC, Biddle A ( 2015 ) . Phenotypic plasticity and epithelial-to-mesenchymal transition in the behaviour and therapeutic response of oral squamous cell carcinoma . Journal of Oral Pathology and Medicine vol. 44 , ( 9 ) 649 - 655 .
Shigeishi H, Biddle A, Gammon L, Rodini CO, Yamasaki M, Seino S, Sugiyama M, Takechi M et al. ( 2015 ) . Elevation in 5-FU-induced apoptosis in head and neck cancer stem cells by a combination of CDHP and GSK3β inhibitors . J Oral Pathol Med vol. 44 , ( 3 ) 201 - 207 .
Gemenetzidis E, Gammon L, Biddle A, Emich H, Mackenzie IC ( 2015 ) . Invasive oral cancer stem cells display resistance to ionising radiation . Oncotarget vol. 6 , ( 41 ) 43964 - 43977 .
Vig N, Biddle A, Gammon L, Emich H, Mackenzie I ( 2014 ) . Implications of the Cancer Stem Cell (CSC) Paradigm for OMFS Patients and Surgeons . British Journal of Oral and Maxillofacial Surgery vol. 52 , ( 8 )
Hufbauer M, Biddle A, Borgogna C, Gariglio M, Doorbar J, Storey A, Pfister H, Mackenzie I et al. ( 2013 ) . Expression of Betapapillomavirus Oncogenes Increases the Number of Keratinocytes with Stem Cell-Like Properties . JOURNAL OF VIROLOGY vol. 87 , ( 22 ) 12158 - 12165 .
Shigeishi H, Biddle A, Gammon L, Emich H, Rodini CO, Gemenetzidis E, Fazil B, Sugiyama M et al. ( 2013 ) . Maintenance of stem cell self-renewal in head and neck cancers requires actions of GSK3β influenced by CD44 and RHAMM . Stem Cells vol. 31 , ( 10 ) 2073 - 2083 .
Biddle A, Gammon L, Fazil B, Mackenzie IC ( 2013 ) . CD44 staining of cancer stem-like cells is influenced by down-regulation of CD44 variant isoforms and up-regulation of the standard CD44 isoform in the population of cells that have undergone epithelial-to-mesenchymal transition . PLoS One vol. 8 , ( 2 )
Gammon L, Biddle A, Heywood HK, Johannessen AC, Mackenzie IC ( 2013 ) . Sub-sets of cancer stem cells differ intrinsically in their patterns of oxygen metabolism . PLoS One vol. 8 , ( 4 )
Biddle A, Mackenzie IC ( 2012 ) . Cancer stem cells and EMT in carcinoma . Cancer Metastasis Rev
VALORANI MG, Montelatici E, Germani A, Biddle A, D'Alessandro D, Strollo R, Patrizi MP, Lazzari L et al. ( 2012 ) . Pre-culturing human adipose tissue mesenchymal stem cells under hypoxia increases their adipogenic and osteogenic differentiation potential . Cell Proliferation vol. 45 , ( 3 ) 225 - 238 .
Biddle A, Liang X, Gammon L, Fazil B, Harper LJ, Emich H, Costea DE, Mackenzie IC ( 2011 ) . Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative . Cancer Res vol. 71 , ( 15 ) 5317 - 5326 .
Gammon L, Biddle A, Fazil B, Harper L, Mackenzie IC ( 2011 ) . Stem cell characteristics of cell sub-populations in cell lines derived from head and neck cancers of Fanconi anemia patients . J Oral Pathol Med vol. 40 , ( 2 ) 143 - 152 .
Valorani MG, Germani A, Otto WR, Harper L, Biddle A, Khoo CP, Lin WR, Hawa MI et al. ( 2010 ) . Hypoxia increases Sca-1/CD44 co-expression in murine mesenchymal stem cells and enhances their adipogenic differentiation potential . Cell Tissue Res vol. 341 , ( 1 ) 111 - 120 .
Harper LJ, Costea DE, Gammon L, Fazil B, Biddle A, Mackenzie IC ( 2010 ) . Normal and malignant epithelial cells with stem-like properties have an extended G2 cell cycle phase that is associated with apoptotic resistance . BMC Cancer vol. 10 ,
Biddle A, Simeoni I, Gurdon JB ( 2009 ) . Xenopus oocytes reactivate muscle gene transcription in transplanted somatic nuclei independently of myogenic factors . DEVELOPMENT vol. 136 , ( 16 ) 2695 - 2703 .
Dragnev KH, Petty WJ, Shah S, Biddle A, Desai NB, Memoli V, Rigas JR, Dmitrovsky E ( 2005 ) . Bexarotene and erlotinib for aerodigestive tract cancer . Journal of Clinical Oncology vol. 23 , ( 34 ) 8757 - 8764 .
Petty WJ, Li N, Biddle A, Bounds R, Nitkin C, Ma Y, Dragnev KH, Freemantle SJ et al. ( 2005 ) . A novel retinoic acid receptor β isoform and retinoid resistance in lung carcinogenesis . Journal of the National Cancer Institute vol. 97 , ( 22 ) 1645 - 1651 .
Petty WJ, Bragnev KH, Memoli VA, Ma Y, Desai NB, Biddle A, Davis TH, Nugent WC et al. ( 2004 ) . Epidermal growth factor receptor tyrosine kinase inhibition represses cyclin D1 in aerodigestive tract cancers . Clinical Cancer Research vol. 10 , ( 22 ) 7547 - 7554 .