Publications: Dr Paul Armstrong

Vadgama A, Boot J, Dark N, Allan HE, Mein CA, Armstrong PC, Warner TD ( 2024 ) . Multiparameter phenotyping of platelets and characterization of the effects of agonists using machine learning . Research and Practice in Thrombosis and Haemostasis vol. 8 , ( 5 )

Chan MV, Chen M-H, Thibord F, Nkambule BB, Lachapelle AR, Grech J, Schneider ZE, de Melendez CW et al. ( 2024 ) . Factors that modulate platelet reactivity as measured by 5 assay platforms in 3429 individuals . Research and Practice in Thrombosis and Haemostasis vol. 8 , ( 3 )

Vulliamy P, Armstrong PC ( 2024 ) . Platelets in Hemostasis, Thrombosis, and Inflammation After Major Trauma . Arteriosclerosis Thrombosis and Vascular Biology vol. 44 , ( 3 ) 545 - 557 .

Alasmari AM, Alsulayyim AS, Alghamdi SM, Philip KEJ, Buttery SC, Banya WAS, Polkey MI, Armstrong PC et al. ( 2023 ) . Oral nitrate supplementation improves cardiovascular risk markers in COPD: ON-BC, a randomised controlled trial . European Respiratory Journal vol. 63 , ( 2 )

Schofield H, Rossetto A, Armstrong PC, Allan HE, Warner TD, Brohi K, Vulliamy P ( 2023 ) . Immature platelet dynamics are associated with clinical outcomes after major trauma . Journal of Thrombosis and Haemostasis vol. 22 , ( 4 ) 926 - 935 .

Armstrong P, kirkby N ( 2023 ) . Widening the prostacyclin paradigm: tissue fibroblasts are a critical site of production and 2 anti-thrombotic protection . Arteriosclerosis, Thrombosis, and Vascular Biology

Allan H, Dark N, Ferreira P, Crescente M, Armstrong P, Warner T ( 2023 ) . PB0878 Platelet-Derived Mitochondria Promote Neutrophil Activation and NETosis . Research and Practice in Thrombosis and Haemostasis vol. 7 ,

Schofield H, Rossetto A, Armstrong PC, Allan HE, Warner TD, Brohi K, Vulliamy P ( 2023 ) . Immature platelet dynamics are associated with clinical outcomes after major trauma .

Yakusheva A, Slater A, Payrastre B, Garcia C, D'Italia G, Allan H, Cosemans JMEM, Harper M et al. ( 2023 ) . Illustrated Abstracts of the 5th EUPLAN International Conference . Research and Practice in Thrombosis and Haemostasis vol. 7 , ( 7 )

Iding AFJ, Kohli S, Manevski SD, Sayar Z, Al Moosawi M, Armstrong PC, Committee IEC ( 2023 ) . Coping with setbacks as early career professionals: transforming negatives into positives . Journal of Thrombosis and Haemostasis vol. 21 , ( 7 ) 1689 - 1691 .

Allan HE, Vadgama A, Armstrong PC, Warner TD ( 2023 ) . What can we learn from senescent platelets, their transcriptomes and proteomes? . Platelets vol. 34 , ( 1 )

Al Moosawi M, Iding A, Armstrong P, Chiasakul T, Campbell R, Casari C, Committee FTIEC, McLintock C et al. ( 2022 ) . Impact of the COVID‐19 pandemic on education and clinical training . Journal of Thrombosis and Haemostasis vol. 19 , ( 9 ) 2099 - 2100 .

Allan HE, Vadgama A, Armstrong PC, Warner TD ( 2022 ) . Platelet ageing: A review . Thrombosis Research vol. 231 , 214 - 222 .

Armstrong PC, Allan HE, Kirkby NS, Gutmann C, Joshi A, Crescente M, Mitchell JA, Mayr M et al. ( 2022 ) . Temporal in vivo platelet labeling in mice reveals age-dependent receptor expression and conservation of specific mRNAs . Blood Advances vol. 6 , ( 23 ) 6028 - 6038 .

Pires ML, Vinokurova M, Shala F, Ahmetaj-Shala B, Armstrong PC, Herschman HR, Mitchell JA, Kirkby NS ( 2022 ) . Abstract 14698: Identifying Sources of Prostacyclin Outside the Vascular Wall and Their Contribution to Cardiovascular Protection . Circulation vol. 146 , ( Suppl_1 ) a14698 - a14698 .

Poole L, Casari C, Manevski SD, Eslick R, Committee FTIEC, Weitz JI, Al Moosawi M, Armstrong P et al. ( 2022 ) . Challenges facing early career women in thrombosis and hemostasis—meeting the needs of the next generation . Journal of Thrombosis and Haemostasis vol. 20 , ( 11 ) 2453 - 2455 .

Gutmann C, Barwari T, Schulte C, Singh B, Theofilatos K, Joshi A, Zampetaki A, Chan MV et al. ( 2022 ) . Oral Presentation No. 093 Assessing different noncoding RNAs as markers of platelet reactivity . Cardiovascular Research . vol. 118 ,

Hsu H, Chan MV, Armstrong PC, Crescente M, Donikian D, Kondo M, Brighton T, Chen V et al. ( 2022 ) . A pilot study assessing the implementation of 96-well plate-based aggregometry (Optimul) in Australia . Pathology vol. 54 , ( 6 ) 746 - 754 .

Gutmann C, Barwari T, Schulte C, Singh B, Theofilatos K, Joshi A, Zampetaki A, Chan M et al. ( 2022 ) . MicroRNA biomarkers of platelet function . Cardiovascular Research . vol. 118 ,

Mitchell JA, Vinokurova M, Lopes-Pires ME, Shala F, Armstrong PC, Ahmetaj-Shala B, Elghazouli Y, Liu B et al. ( 2022 ) . Tissue fibroblasts are a critical source of prostacyclin and anti-thrombotic protection .

Grech J, Chan MV, Ochin C, Lachapelle A, Thibord F, Schneider Z, Nkambule BB, Armstrong PCJ et al. ( 2022 ) . Serotonin-affecting antidepressant use in relation to platelet reactivity . Clin Pharmacol Ther

Gutmann C, Barwari T, Schulte C, Singh B, Theofilatos K, Joshi A, Zampetaki A, Chan MV et al. ( 2022 ) . Assessing different noncoding RNAs as markers of platelet reactivity . CARDIOVASCULAR RESEARCH . vol. 118 ,

Pires ML, Vinokurova M, Shala F, Ahmetaj-Shala B, Armstrong PC, Herschman HR, Mitchell JA, Kirkby NS ( 2022 ) . Identifying Sources of Prostacyclin Outside the Vascular Wall and Their Contribution to Cardiovascular Protection . CIRCULATION . vol. 146 ,

Joshi A, Schmidt LE, Burnap SA, Lu R, Chan MV, Armstrong PC, Baig F, Gutmann C et al. ( 2022 ) . Neutrophil-Derived Protein S100A8/A9 Alters the Platelet Proteome in Acute Myocardial Infarction and Is Associated With Changes in Platelet Reactivity . Arterioscler Thromb Vasc Biol vol. 42 , ( 1 ) 49 - 62 .

Shih C, Chan MV, Kirkby NS, Vojnovic I, Mitchell JA, Armstrong PC, Warner TD ( 2021 ) . Platelet inhibition by P2Y12 antagonists is potentiated by adenosine signalling activators . British Journal of Pharmacology vol. 178 , ( 23 ) 4758 - 4771 .

Allan HE, Hayman MA, Marcone S, Chan MV, Edin ML, Maffucci T, Joshi A, Menke L et al. ( 2021 ) . Proteome and functional decline as platelets age in the circulation . Journal of Thrombosis and Haemostasis vol. 19 , ( 12 ) 3095 - 3112 .

Chan MV, Barwari T, Huffman D, Armstrong PC, Santer P, Kiechl S, Willeit J, Mayr M et al. ( 2018 ) . Platelet reactivity in an elderly and healthy population . Proceedings for Annual Meeting of The Japanese Pharmacological Society . vol. WCP2018 , or25 - or22 .

Crescente M, Armstrong PC, Chan MV, Edin ML, Maffucci T, Kirkby NS, Mitchell JA, Zeldin DC et al. ( 2018 ) . Understanding the cardiovascular effects of low dose aspirin by using a platelet COX-1-/- mouse model . Proceedings for Annual Meeting of The Japanese Pharmacological Society . vol. WCP2018 ,

Mitchell JA, Kirkby NS, Ahmetaj-Shala B, Armstrong PC, Crescente M, Ferreira P, Lopes Pires ME, Vaja R et al. ( 2020 ) . Cyclooxygenases and the cardiovascular system . Pharmacology & Therapeutics vol. 217 ,

Crescente M, Armstrong PC, Kirkby NS, Edin ML, Chan MV, Lih FB, Jiao J, Maffucci T et al. ( 2020 ) . Profiling the eicosanoid networks that underlie the anti- and pro-thrombotic effects of aspirin . The FASEB Journal

Vulliamy P, Montague SJ, Gillespie S, Chan MV, Coupland LA, Andrews RK, Warner TD, Gardiner EE et al. ( 2020 ) . Loss of GPVI and GPIbα contributes to trauma-induced platelet dysfunction in severely injured patients . Blood advances vol. 4 , ( 12 ) 2623 - 2630 .

Armstrong PC, Ferreira PM, Chan MV, Lundberg Slingsby MH, Crescente M, Shih C-C, Kirkby NS, Hobbs AJ et al. ( 2020 ) . Combination of cyclic nucleotide modulators with P2Y₁₂ receptor antagonists as anti-platelet therapy . Journal of thrombosis and haemostasis : JTH vol. 18 , ( 7 ) 1705 - 1713 .

Chan MV, Chen M-H, Barwari T, Huffman JE, Armstrong PC, Hwang S-J, Santer P, Wierer B et al. ( 2020 ) . Platelet Reactivity in Individuals Over 65 Years Old Is not Modulated by Age . Circulation Research

Mitchell JA, Shala F, Elghazouli Y, Warner TD, Gaston-Massuet C, Crescente M, Armstrong PC, Herschman HR et al. ( 2019 ) . Cell-Specific Gene Deletion Reveals the Antithrombotic Function of COX1 and Explains the Vascular COX1/Prostacyclin Paradox . Circulation Research vol. 125 , ( 9 ) 847 - 854 .

Vulliamy P, Gillespie S, Armstrong P, Allan H, Warner T, Brohi K ( 2019 ) . Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage . Proceedings of the National Academy of Sciences

Patel D, Warner TD, Armstrong PC ( 2019 ) . ICAM-1 contributes to the preferential binding of platelets to classical and intermediate monocyte subsets over neutrophils . BRITISH JOURNAL OF PHARMACOLOGY . Conference: Pharmacology 2018 from: 20/12/2018 to: 18/12/2018 , vol. 176 , 3038 - 3039 .

Lucotti S, Cerutti C, Soyer M, Gil-Bernabé AM, Gomes AL, Allen PD, Smart S, Markelc B et al. ( 2019 ) . Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2 . Journal of Clinical Investigation vol. 129 , ( 5 ) 1845 - 1862 .

Barwari T, Eminaga S, Mayr U, Lu R, Armstrong PC, Chan MV, Sahraei M, Fernández-Fuertes M et al. ( 2018 ) . Inhibition of profibrotic microRNA-21 affects platelets and their releasate . JCI Insight vol. 3 , ( 21 )

Hayman M, Armstrong P, Chan M, Warner T ( 2017 ) . Functional Analyses of Reticulated Platelets . The FASEB Journal . vol. 31 ,

Barwari T, Eminaga S, Lu R, Armstrong PC, Schulte C, Lynch M, Chan MV, Barallobre-Barreiro J et al. ( 2018 ) . Abstract 300: MicroRNA-21 Affects Platelets and Their Releasate: A Novel Mechanism for the Anti-Fibrotic Effects of MicroRNA-21 Inhibition . Circulation Research . vol. 123 ,

Lucotti S, Cerutti C, Soyer M, Gil-Bernabé AM, Gomes AL, Allen PD, Smart S, Markelc B et al. ( 2018 ) . Abstract 4196: Aspirin inhibits metastasis in the intravascular phase through the blockade of COX-1-TXA2 pathway in platelets . Cancer Research . vol. 78 , 4196 - 4196 .

Barwari T, Eminaga S, Armstrong P, Chan M, Lu R, Barallobre-Barreiro J, Yin X, Pechlaner R et al. ( 2018 ) . 82 Microrna-21 regulates transforming growth factor beta-1 release from platelets . Heart . Conference: Basic Science vol. 104 ,

Chan MV, Leadbeater PD, Watson SP, Warner TD ( 2018 ) . Not all light transmission aggregation assays are created equal: qualitative differences between light transmission and 96-well plate aggregometry . Platelets1 - 4 .

Crescente M, Menke L, Chan MV, Armstrong PC, Warner TD ( 2018 ) . Eicosanoids in platelets and the effect of their modulation by aspirin in the cardiovascular system (and beyond) . British Journal of Pharmacology vol. 176 , ( 8 ) 988 - 999 .

Chan MV, Armstrong PC, Warner TD ( 2018 ) . 96-well plate-based aggregometry . Platelets1 - 6 .

Lundberg Slingsby MH, Gliemann L, Thrane M, Rytter N, Egelund J, CHAN MV, Armstrong PC, Warner TD et al. ( 2018 ) . Platelet responses to pharmacological and physiological interventions in middle-aged men with different habitual physical activity levels . Acta Physiol (Oxf)

Mitchell JA, Shala F, Elghazouli Y, Armstrong PC, Vadgama A, Herschman HR, Kirkby NS ( 2018 ) . Renal or Vascular Deletion of COX-2 Increases Thrombotic Tone: Relevance to Cardiovascular Side Effects of Non-Steroidal Anti-Inflammatory Drugs . CIRCULATION . vol. 138 ,

VULLIAMY P, GILLESPIE S, ARMSTRONG P, CHAN M, DAVENPORT R, WARNER T, BROHI K ( 2017 ) . Platelets Shift Towards a Procoagulant and Proin ammatory Phenotype at the Expense of Aggregation During Trauma Hemorrhage: a Potential Role of Extracellular Histones . Circulation . Conference: American Heart Association Scientific Sessions ( Anaheim, CA ) from: 11/11/2017 to: 15/11/2017 , vol. e448-467 ,

Armstrong PC, Peter K ( 2017 ) . GPIIb/IIIa inhibitors: From bench to bedside and back to bench again . Thrombosis and Haemostasis vol. 107 , ( 05 ) 808 - 814 .

Crescente M, Armstrong PC, CHAN MV, Edin ML, Lih FB, Jiao J, Gaston-Massuet C, Cottrell GS et al. ( 2017 ) . PLATELET COX-1 KNOCKOUT MOUSE AS A MODEL OF THE EFFECTS OF ASPIRIN IN THE CARDIOVASCULAR SYSTEM . HEART . Conference: BCS Annual Conference, ‘Cardiology at the Extremes' vol. 103 , A108 - A109 .

Armstrong PC, Hoefer T, Knowles RB, Tucker AT, Hayman MA, Ferreira PM, Chan MV, Warner TD ( 2017 ) . Newly Formed Reticulated Platelets Undermine Pharmacokinetically Short-Lived Antiplatelet Therapies . Arterioscler Thromb Vasc Biol vol. 37 , ( 5 ) 949 - 956 .

Barwari T, Eminaga S, Armstrong PC, Chan MV, Lu R, Barallobre-Barreiro J, Yin X, Pechlaner R et al. ( 2017 ) . MicroRNA-21 Regulates Transforming Growth Factor Beta-1 Release From Platelets: A Novel Mechanism for the Anti-Fibrotic Effects of MicroRNA-21 Inhibition . CIRCULATION . vol. 136 ,

Mitchell JA, Shala F, Ahmetaj-Shala B, Jiao J, Armstrong PC, Chan MV, Crescente M, Warner TD et al. ( 2017 ) . Novel Tissue-specific Cyclooxygenase-1 Knockout Mice Demonstrate a Dominant Role for Endothelial Cyclooxygenase-1 in Prostacyclin Production . CIRCULATION . vol. 136 ,

Vulliamy P, Gillespie S, Armstrong PC, Chan MV, Davenport RA, Warner TD, Brohi K ( 2017 ) . Platelets Shift Towards a Procoagulant and Proinflammatory Phenotype at the Expense of Aggregation During Trauma Hemorrhage: a Potential Role of Extracellular Histones . CIRCULATION . vol. 136 , E464 - E464 .

Ferreira P, Armstrong P, Chan M, Warner T ( 2016 ) . 169 Soluble Guanylate Cyclase Activators as Combination Anti-Platelet Therapy with P2Y12 Inhibitors and PDE Inhibitors: In vivo and Ex vivo Studies . Heart . vol. 102 ,

Knowles R, D’Silva L, Armstrong P, Chan M, Lawrence M, Standford S, Sabre A, Tucker A et al. ( 2016 ) . 186 Platelets as Key Regulators of Fibrin-Clot Architecture as Assessed by Fractal Analysis of Viscoelastic Properties; Effects of Standard Anti-Platelet Therapies . Heart . vol. 102 ,

Knowles R, D’Silva L, Stanford S, Armstrong P, Chan M, Tucker A, Ferreira P, Sabra A et al. ( 2016 ) . INSIGHTS INTO THE ROLE OF PLATELETS IN FIBRIN CLOT FORMATION AND THE EFFICACY OF ANTI-PLATELET THERAPIES . Journal of the American College of Cardiology . vol. 67 ,

Warner TD, Armstrong PC, Chan MV, Knowles RB ( 2016 ) . The importance of endothelium-derived mediators to the efficacy of dual anti-platelet therapy . Expert Review of Hematology vol. 9 , ( 3 ) 223 - 225 .

Chan MV, Knowles RBM, Lundberg MH, Tucker AT, Mohamed NA, Kirkby NS, Armstrong PCJ, Mitchell JA et al. ( 2016 ) . P2Y12 receptor blockade synergizes strongly with nitric oxide and prostacyclin to inhibit platelet activation . British Journal of Clinical Pharmacology vol. 81 , ( 4 ) 621 - 633 .

Kaudewitz D, Skroblin P, Bender LH, Barwari T, Willeit P, Pechlaner R, Sunderland NP, Willeit K et al. ( 2015 ) . Association of MicroRNAs and YRNAs With Platelet Function . Circulation Research vol. 118 , ( 3 ) 420 - 432 .

Ahmetaj-Shala B, Kirkby NS, Knowles R, Al'Yamani M, Mazi S, Wang Z, Tucker AT, Mackenzie LS et al. ( 2015 ) . Reply to Letter Regarding Article, “Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine . Circulation vol. 132 , ( 17 ) e213 - e214 .

Hoefer T, Armstrong PC, Finsterbusch M, Chan MV, Kirkby NS, Warner TD ( 2015 ) . Drug-Free Platelets Can Act as Seeds for Aggregate Formation During Antiplatelet Therapy . Arteriosclerosis Thrombosis and Vascular Biology vol. 35 , ( 10 ) 2122 - 2133 .

Armstrong PCJ, Kirkby NS, Chan MV, Finsterbusch M, Hogg N, Nourshargh S, Warner TD ( 2015 ) . Novel whole blood assay for phenotyping platelet reactivity in mice identifies ICAM-1 as a mediator of platelet-monocyte interaction . Blood vol. 126 , ( 10 ) e11 - e18 .

Knowles R, Chan M, Hayman M, Armstrong P, Tucker A, Timmis A, Warner T ( 2015 ) . 158 The Anti-Platelet Effectiveness of P2Y12 Receptor Blockade is Strongly Influenced by the Endothelium-Derived Mediators Nitric Oxide and Prostacyclin . Heart vol. 101 , ( Suppl 4 )

Knowles R, Chan M, Lundberg M, Kirkby N, Shih C-C, Armstrong P, Hayman M, Vojnovic I et al. ( 2015 ) . 213 Synergy between Endothelial Mediators and P2Y12 Receptor Blockade as a Potential Determinant in Tailoring Anti-Platelet Therapy . Heart . vol. 101 ,

Khanna V, Armstrong PCJ, Warner TD, Curzen N ( 2015 ) . Prostaglandin E1 potentiates the effects of P2Y12 blockade on ADP-mediated platelet aggregation in vitro: Insights using short thromboelastography . Platelets vol. 26 , ( 7 ) 689 - 692 .

Ross CL, Galloway-Phillipps N, Armstrong PC, Mitchell JA, Warner TD, Brearley C, Ito M, Tunstall T et al. ( 2015 ) . Protocol for a human in vivo model of acute cigarette smoke inhalation challenge in smokers with COPD: monitoring the nasal and systemic immune response using a network biology approach . BMJ Open vol. 5 , ( 1 )

Armstrong PC, Warner TD ( 2015 ) . Characterising cell-type interactions following platelet activation in a novel low volume whole blood assay . JOURNAL OF THROMBOSIS AND HAEMOSTASIS . vol. 13 , 657 - 657 .

Ahmetaj-Shala B, Kirkby NS, Knowles R, Al'Yamani M, Mazi S, Wang Z, Tucker AT, Mackenzie L et al. ( 2015 ) . Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine Novel Explanation of Cardiovascular Side Effects Associated With Anti-Inflammatory Drugs . CIRCULATION vol. 131 , ( 7 ) 633 - U113 .

Knowles R, Chan M, Hayman M, Armstrong P, Tucker A, Timmis A, Warner T ( 2015 ) . THE ANTI-PLATELET EFFECTIVENESS OF P2Y12 RECEPTOR BLOCKADE IS STRONGLY INFLUENCED BY THE ENDOTHELIUM- DERIVED MEDIATORS NITRIC OXIDE AND PROSTACYCLIN . HEART . vol. 101 , A90 - A91 .

Knowles RB, Chan MV, Armstrong PC, Shih C-C, Hayman MA, Vojnovic I, Tucker AT, Timmis AD et al. ( 2015 ) . The effectiveness of P2Y12 receptor blockade is strongly determined by the presence of endothelial Mediators prostacyclin and nitric oxide . JOURNAL OF THROMBOSIS AND HAEMOSTASIS . vol. 13 , 784 - 784 .

Ahmetaj-Shala B, Kirkby NS, Knowles R, Al’Yamani M, Mazi S, Wang Z, Tucker AT, Mackenzie L et al. ( 2015 ) . Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine . Circulation . vol. 131 , 633 - 642 .

Knowles RB, Chan MV, Armstrong PC, Shih C-C, Hayman MA, Vojnovic I, Tucker AT, Timmis AD et al. ( 2014 ) . The Effectiveness of P2Y12 Receptor Antagonist Therapy is Strongly Determined by Endothelial Mediators of Platelet Function . CIRCULATION . vol. 130 ,

ARMSTRONG PCJ, HU H, RIVERA J, RIGBY S, CHEN Y, HOWDEN BP, GARDINER E, PETER K ( 2012 ) . Staphylococcal superantigen‐like protein 5 induces thrombotic and bleeding complications in vivo: inhibition by an anti‐SSL5 antibody and the glycan Bimosiamose . Journal of Thrombosis and Haemostasis vol. 10 , ( 12 ) 2607 - 2609 .

Wang X, Hagemeyer CE, Hohmann JD, Leitner E, Armstrong PC, Jia F, Olschewski M, Needles A et al. ( 2012 ) . Novel Single-Chain Antibody-Targeted Microbubbles for Molecular Ultrasound Imaging of Thrombosis . Circulation vol. 125 , ( 25 ) 3117 - 3126 .

Topcic D, Kim W, Holien JK, Jia F, Armstrong PC, Hohmann JD, Straub A, Krippner G et al. ( 2011 ) . An Activation-Specific Platelet Inhibitor That Can Be Turned On/Off by Medically Used Hypothermia . Arteriosclerosis Thrombosis and Vascular Biology vol. 31 , ( 9 ) 2015 - 2023 .

Armstrong PC, Kirkby NS, Zain ZN, Emerson M, Mitchell JA, Warner TD ( 2011 ) . Thrombosis Is Reduced by Inhibition of COX-1, but Unaffected by Inhibition of COX-2, in an Acute Model of Platelet Activation in the Mouse . PLOS ONE vol. 6 , ( 5 )

Hu H, Armstrong PCJ, Khalil E, Chen Y-C, Straub A, Li M, Soosairajah J, Hagemeyer CE et al. ( 2011 ) . GPVI and GPIbα Mediate Staphylococcal Superantigen-Like Protein 5 (SSL5) Induced Platelet Activation and Direct toward Glycans as Potential Inhibitors . PLOS ONE vol. 6 , ( 4 )

Armstrong PCJ, Leadbeater PD, Chan MV, Kirkby NS, Jakubowski JA, Mitchell JA, Warner TD ( 2011 ) . In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation . J Thromb Haemost vol. 9 , ( 3 ) 552 - 561 .

Chan MV, Armstrong PCJ, Papalia F, Kirkby NS, Warner TD ( 2011 ) . Optical multichannel (optimul) platelet aggregometry in 96-well plates as an additional method of platelet reactivity testing . Platelets vol. 22 , ( 7 ) 485 - 494 .

Warner TD, Armstrong PCJ, Curzen NP, Mitchell JA ( 2010 ) . Dual antiplatelet therapy in cardiovascular disease: does aspirin increase clinical risk in the presence of potent P2Y12 receptor antagonists? . Heart vol. 96 , ( 21 ) 1693 - 1694 .

Moreno L, McMaster SK, Gatheral T, Bailey LK, Harrington LS, Cartwright N, Armstrong PCJ, Warner TD et al. ( 2010 ) . Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages . BRIT J PHARMACOL vol. 160 , ( 8 ) 1997 - 2007 .

Armstrong PCJ, Dhanji ARA, Tucker AT, Mitchell JA, Warner TD ( 2010 ) . Reduction of platelet thromboxane A(2) production ex vivo and in vivo by clopidogrel therapy . J THROMB HAEMOST vol. 8 , ( 3 ) 613 - 615 .

Armstrong P, Hu H, Chen Y, Li M, Bassler N, Fu J, Hagemeyer C, Gardner E et al. ( 2010 ) . Staphylococcal Superantigen-like Protein 5 (SSL5), a Prothrombotic Exotoxin of Staphylococcus aureus Infections and Potential Novel Treatment Strategies . Heart Lung and Circulation vol. 19 , s93 - s94 .

Shinhmar S, Truss N, Armstrong P, Vojnovic I, Warner T ( 2010 ) . Use of a 96-well plate method for the determination of the anti-platelet effectiveness of a novel NO releasing aspirin molecule . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 70 , 303 - 303 .

Armstrong PCJ, Dhanji AA, Tucker AT, Mitchell JA, Warner TD ( 2009 ) . URINARY 11-DEHYDRO-THROMBOXANE B2 AS A MARKER OF THE ANTI-PLATELET EFFECTS OF CLOPIDOGREL OR ASPIRIN THERAPY IN HEALTHY MALE VOLUNTEERS . HEART . vol. 95 ,

Truss NJ, Armstrong PCJ, Liverani E, Vojnovic I, Warner TD ( 2009 ) . Heparin but not citrate anticoagulation of blood preserves platelet function for prolonged periods . J THROMB HAEMOST vol. 7 , ( 11 ) 1897 - 1905 .

Armstrong PCJ, Dhanji AR, Truss NJ, Zain ZNM, Tucker AT, Mitchell JA, Warner TD ( 2009 ) . Utility of 96-well plate aggregometry and measurement of thrombi adhesion to determine aspirin and clopidogrel effectiveness . THROMB HAEMOSTASIS vol. 102 , ( 4 ) 772 - 778 .

Ali FY, Armstrong PCJ, Dhanji ARA, Tucker AT, Paul-Clark MJ, Mitchell JA, Warner TD ( 2009 ) . Antiplatelet Actions of Statins and Fibrates Are Mediated by PPARs . ARTERIOSCL THROM VAS vol. 29 , ( 5 ) 706 - 711 .

Armstrong PCJ, Dhanji AA, Truss NJ, Zain ZNM, Tucker AT, Mitchell JA, Warner TD ( 2009 ) . Determination and differentiation of aspirin and clopidogrel effectiveness by 96-well plate aggregometry and measurement of thrombi adhesion . JOURNAL OF THROMBOSIS AND HAEMOSTASIS . vol. 7 , 572 - 573 .

Truss NJ, Armstrong PCJ, Shinhmar SK, Warner TD ( 2009 ) . Nitric oxide inhibits platelet aggregation independantly from formation of thromboxane A2 . JOURNAL OF THROMBOSIS AND HAEMOSTASIS . vol. 7 , 933 - 933 .

Truss NJ, Ali FY, Armstrong PCJ, Warner TD ( 2009 ) . The effect of hydrogen sulphide on platelet action . JOURNAL OF THROMBOSIS AND HAEMOSTASIS . vol. 7 , 933 - 933 .

Armstrong PCJ, Dhanji AA, Tucker AT, Mitchell JA, Warner TD ( 2009 ) . Urinary 11-dehydro-thromboxane B2 as a marker of the anti-platelet effects of clopidogrel or aspirin therapy in healthy male volunteers . JOURNAL OF THROMBOSIS AND HAEMOSTASIS . vol. 7 , 573 - 573 .

Armstrong PCJ, Truss NJ, Ali FY, Dhanji AA, Vojnovic I, Zain ZNM, Bishop-Bailey D, Paul-Clark MJ et al. ( 2008 ) . Aspirin and the in vitro linear relationship between thromboxane A(2)-mediated platelet aggregation and platelet production of thromboxane A(2) . J THROMB HAEMOST vol. 6 , ( 11 ) 1933 - 1943 .

Zain ZNM, Armstrong PCJ, Pearson NJ, Mitchell JA, Warner TD ( 2008 ) . Evaluation of aspirin inhibition of platelet aggregation induced by combination of collagen and adrenaline in a 96-well plate format . HEART . vol. 94 ,

Armstrong PCJ, Zain ZNM, Truss NJ, Vojnovic I, Bishop-Bailey D, Mitchell JA, Warner TD ( 2008 ) . Linear relationship between platelet aggregation and thromboxane A(2) production . HEART . vol. 94 ,

Truss NJ, Armstrong PCJ, Zain ZN, Ali FY, Warner TD ( 2008 ) . Platelet aggregation after storage of whole blood at 4 degrees C . HEART . vol. 94 ,

Papalia F, Armstrong PCJ, Pearson NJ, Zain ZNM, Ali FY, Vojnovic I, Warner TD ( 2008 ) . Development of a routine test of platelet reactivity . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 65 , 979 - 979 .