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Research

Publications: Prof Amrita Ahluwalia

Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Learoyd AE, Forooghi N, Ramaseshan R et al. ( 2024 ) . CTCA Prior to Invasive Coronary Angiography in Patients With Previous Bypass Surgery: Patient-Related Outcomes, Imaging Resource Utilization, and Cardiac Events at 3 Years From the BYPASS-CTCA Trial . Circulation Cardiovascular Interventions
Massimo G, Dyson N, Olotu F, Khambata RS, Ahluwalia A ( 2024 ) . Potential Opportunities for Pharmacogenetic-Based Therapeutic Exploitation of Xanthine Dehydrogenase in Cardiovascular Disease . Antioxidants vol. 13 , ( 12 )
Rathod KS, Mathur A, Shabbir A, Khambata RS, Lau C, Beirne A-M, Chhetri I, Ono M et al. ( 2024 ) . The NITRATE-OCT study-inorganic nitrate reduces in-stent restenosis in patients with stable coronary artery disease: a double-blind, randomised controlled trial . EClinicalMedicine vol. 77 ,
Insel PA, Amara SG, Ahluwalia A ( 2024 ) . Introduction to the Theme “Novel Therapeutics with the Potential to Advance Health Care” . The Annual Review of Pharmacology and Toxicology
Vyas R, Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Learoyd AE, Forooghi N et al. ( 2024 ) . OP5 Diagnostic accuracy of CTCA for graft and native disease assessment in patients with previous CABG: insights from the BYPASS-CTCA trial . Conference: OP5 Diagnostic accuracy of CTCA for graft and native disease assessment in patients with previous CABG: insights from the BYPASS-CTCA triala2.2 - a2a2 .
Jones DA, Beirne A-M, Kelham M, Wynne L, Andiapen M, Rathod KS, Parakaw T, Adams J et al. ( 2024 ) . Inorganic nitrate benefits contrast-induced nephropathy after coronary angiography for acute coronary syndromes: the NITRATE-CIN trial . European Heart Journal vol. 45 , ( 18 ) 1647 - 1658 .
Kelham M, Beirne A-M, Rathod KS, Andiapen M, Wynne L, Ramaseshan R, Learoyd AE, Forooghi N et al. ( 2024 ) . The effect of CTCA guided selective invasive graft assessment on coronary angiographic parameters and outcomes: Insights from the BYPASS-CTCA trial . Journal of Cardiovascular Computed Tomography vol. 18 , ( 3 ) 291 - 296 .
Sienel RI, Mamrak U, Biller J, Roth S, Zellner A, Parakaw T, Khambata RS, Liesz A et al. ( 2023 ) . Inhaled nitric oxide suppresses neuroinflammation in experimental ischemic stroke . Journal of Neuroinflammation vol. 20 , ( 1 )
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod K et al. ( 2023 ) . Corrigendum to “Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?” [Redox Biol. 4 (67) (2023) 102864] . Redox Biology vol. 67 ,
Jones DA, Beirne A-M, Kelham M, Rathod KS, Andiapen M, Wynne L, Godec T, Forooghi N et al. ( 2023 ) . Computed Tomography Cardiac Angiography Before Invasive Coronary Angiography in Patients With Previous Bypass Surgery: The BYPASS-CTCA Trial . Circulation vol. 148 , ( 18 ) 1371 - 1380 .
Shabbir A, Chhetri I, Khambata RS, Parakaw T, Lau C, Aubdool MABN, Massimo G, Dyson N et al. ( 2023 ) . A double-blind, randomised, placebo-controlled parallel study to investigate the effect of sex and dietary nitrate on COVID-19 vaccine-induced vascular dysfunction in healthy men and women: protocol of the DiNOVasc-COVID-19 study . Trials vol. 24 , ( 1 )
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod KS et al. ( 2023 ) . Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health? . Redox Biology vol. 67 ,
Rathod K, Warren H, Tufaro V, Jain A, Ono M, Chhetri I, Garcia-Garcia H, Bourantas C et al. ( 2023 ) . 34 Investigation of the effects of dietary nitrate on vascular function, platelet reactivity and restenosis in patients with stable angina (nitrate-oct study) . Conference: Acute coronary syndromes & Interventional Cardiologya37 - a38 .
Rathod KS, Shabbir A, Jones DA, Khambata RS, Lau C, Beirne A-M, Ono M, Chhetri I et al. ( 2023 ) . D Investigation of the effects of dietary nitrate on vascular function, platelet reactivity and restenosis in patients with stable angina (NITRATE-OCT study) . Conference: Young investigators awarda314 - a315 .
Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD et al. ( 2023 ) . Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow . Science Signaling vol. 16 , ( 786 )
Panettieri RA, Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y et al. ( 2023 ) . BJP recommendations for publishing research on tobacco smoke and environmental tobacco smoke exposure . British Journal of Pharmacology vol. 180 , ( 12 ) 1537 - 1541 .
Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Ji Y, Panettieri RA et al. ( 2023 ) . Considering and reporting sex as an experimental variable II: An update on progress in the British Journal of Pharmacology . British Journal of Pharmacology vol. 180 , ( 9 ) 1191 - 1196 .
Hikin LJ, Ho J, Morley SR, Ahluwalia A, Smith PR ( 2023 ) . Sodium nitrite poisoning: A series of 20 fatalities in which post-mortem blood nitrite and nitrate concentrations are reported . Forensic Science International vol. 345 ,
Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC et al. ( 2023 ) . Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans . Journal of Clinical Investigation vol. 133 , ( 2 )
Stanford SC, Alexander S, Cirino G, George CH, Insel PA, Kendall D, Panettieri RAJ, Patel HH et al. ( 2023 ) . Considering And Reporting Sex As An Experimental Variable: An Update On Progress In The British Journal Of Pharmacology . BRITISH JOURNAL OF PHARMACOLOGY . vol. 180 , 621 - 621 .
Khambata R, Fernandes D, Massimo G, Ruivo E, Gee LC, Foster J, Goddard A, Curtis M et al. ( 2023 ) . Local delivery of nitric oxide prevents endothelial dysfunction in periodontitis . BRITISH JOURNAL OF PHARMACOLOGY . vol. 180 , 15 - 16 .
Massimo G, Khambata R, Chapman T, Birchall K, Borghi C, Ahluwalia A ( 2023 ) . Natural Mutations Of Human Xdh Promote The Nitirte (No2-)-Reductase Capacity Of Xanthine Oxidoreductase: A Novel Mechanism To Promote Redox Health? . BRITISH JOURNAL OF PHARMACOLOGY . vol. 180 , 51 - 52 .
Dyson N, Khambata R, Massimo G, Parakaw T, Rathod K, Ahluwalia A ( 2023 ) . Nitrite reductase activity of liver-derived Xanthine Oxidoreductase maintains cardiovascular homeostasis . BRITISH JOURNAL OF PHARMACOLOGY . vol. 180 , 186 - 187 .
Fernandes D, Khambata RS, Massimo G, Ruivo E, Gee LC, Foster J, Goddard A, Curtis M et al. ( 2022 ) . Local delivery of nitric oxide prevents endothelial dysfunction in periodontitis . Pharmacological Research vol. 188 ,
Ingrande J, Patel HH, Kendall D, Stefanska B, Alexander S, Bakhle M, Cirino G, Docherty JR et al. ( 2022 ) . Guidance for the use and reporting of anaesthetic agents in BJP manuscripts involving work with animals . British Journal of Pharmacology vol. 180 , ( 3 ) 255 - 263 .
Hikin L, Ahluwalia A, Morley S, Smith P ( 2022 ) . Sodium nitrite poisoning; A case series of 15 fatalities . Toxicologie Analytique et Clinique vol. 34 , ( 3 ) s48 - s49 .
Curtis MJ, Alexander SPH, Cirino G, George CH, Kendall DA, Insel PA, Izzo AA, Ji Y et al. ( 2022 ) . Planning experiments: Updated guidance on experimental design and analysis and their reporting III . British Journal of Pharmacology vol. 179 , ( 15 ) 3907 - 3913 .
Shabbir A, Rathod K, Primus C, Lau C, Chhetri I, Ono M, Khambata R, Massimo G et al. ( 2022 ) . BS37 Leukocytic nitrate reductase activity mitigates systemic inflammation-induced endothelial dysfunction in humans by accelerating resolution . Conference: Basic sciencea167.1 - a1a167 .
Spitschan M, Santhi N, Ahluwalia A, Fischer D, Hunt L, Karp NA, Lévi F, Pineda-Torra I et al. ( 2022 ) . Sex differences and sex bias in human circadian and sleep physiology research . eLife vol. 11 ,
Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Moreira SAM, Rathod K, Chen J et al. ( 2022 ) . 20‐hydroxyeicosatetraenoic acid (20‐HETE) is a pivotal endogenous ligand for TRPV1‐mediated neurogenic inflammation in the skin . British Journal of Pharmacology vol. 179 , ( 7 ) 1450 - 1469 .
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S et al. ( 2021 ) . The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction . Am J Cardiovasc Dis vol. 11 , ( 5 ) 659 - 678 .
Maffia P, Antoniades C, Ahluwalia A, Cirino G ( 2021 ) . Molecular imaging—The first visual themed issue published in the British Journal of Pharmacology . British Journal of Pharmacology vol. 178 , ( 21 ) 4213 - 4215 .
Primus C, Masucci M, Whitear C, Moreira SAM, Kumar NA, Chhetri I, Rathod KS, Khambata R et al. ( 2021 ) . A pro-resolving phenotype underpins the anti-inflammatory effects of inorganic nitrate . European Heart Journal vol. 42 , ( Supplement_1 )
Lau C, Shabbir A, Rathod KS, Chhetri I, Ono M, Hamers AJP, Amarin JJ, Ibrahim A et al. ( 2021 ) . Inorganic nitrate attenuates endothelial dysfunction consequent to systemic inflammation . European Heart Journal vol. 42 , ( Supplement_1 )
Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V et al. ( 2021 ) . Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers . European Heart Journal vol. 42 , ( Supplement_1 )
Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP et al. ( 2021 ) . Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide . British Journal of Pharmacology vol. 179 , ( 20 ) 4757 - 4777 .
Beirne A-M, Rathod KS, Castle E, Andiapen M, Richards A, Bellin A, Hammond V, Godec T et al. ( 2021 ) . The BYPASS-CTCA Study: the value of Computed Tomography Cardiac Angiography (CTCA) in improving patient-related outcomes in patients with previous bypass operation undergoing invasive coronary angiography: Study Protocol of a Randomised Controlled Trial . Annals of Translational Medicine vol. 0 , ( 0 ) 0 - 0 .
Wang J, Mei F, Bai L, Zhou S, Liu D, Yao L, Ahluwalia A, Ghiladi RA et al. ( 2021 ) . Serum nitrite and nitrate: A potential biomarker for post-covid-19 complications? . Free Radical Biology and Medicine vol. 175 , 216 - 225 .
George CH, Alexander SPH, Cirino G, Insel PA, Izzo AA, Ji Y, Kendall DA, Panettieri RA et al. ( 2021 ) . Editorial policy regarding the citation of preprints in the British Journal of Pharmacology (BJP) . British Journal of Pharmacology vol. 178 , ( 18 ) 3605 - 3610 .
Beirne A-M, Mitchelmore O, Palma S, Andiapen M, Rathod KS, Hammond V, Bellin A, Cooper J et al. ( 2021 ) . NITRATE-CIN Study: Protocol of a Randomized (1:1) Single-Center, UK, Double-Blind Placebo-Controlled Trial Testing the Effect of Inorganic Nitrate on Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography for Acute Coronary Syndromes . Journal of Cardiovascular Pharmacology and Therapeutics vol. 26 , ( 4 ) 303 - 309 .
Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V et al. ( 2021 ) . Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers . EUROPEAN HEART JOURNAL . vol. 42 , 3009 - 3009 .
Kelham M, Choudry FA, Hamshere S, Beirne A-M, Rathod KS, Baumbach A, Ahluwalia A, Mathur A et al. ( 2020 ) . Therapeutic Implications of COVID-19 for the Interventional Cardiologist . Journal of Cardiovascular Pharmacology and Therapeutics vol. 26 , ( 3 ) 203 - 216 .
Shabbir A, Ahluwalia A ( 2020 ) . Second wave and second opportunity: capitalizing on cardiovascular research activity during the COVID-19 pandemic . European Heart Journal - Quality of Care and Clinical Outcomes vol. 7 , ( 3 ) 321 - 322 .
Shabbir A, Rathod KS, Khambata RS, Ahluwalia A ( 2020 ) . Sex Differences in the Inflammatory Response: Pharmacological Opportunities for Therapeutics for Coronary Artery Disease . The Annual Review of Pharmacology and Toxicology vol. 61 , ( 1 ) 1 - 27 .
Lilley E, Stanford SC, Kendall DE, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA et al. ( 2020 ) . ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020 . British Journal of Pharmacology vol. 177 , ( 16 ) 3611 - 3616 .
du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC et al. ( 2020 ) . Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 . PLOS Biology vol. 18 , ( 7 )
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research . BMC Veterinary Research vol. 16 , ( 1 )
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research* . Cerebrovascular and Brain Metabolism Reviews vol. 40 , ( 9 ) 1769 - 1777 .
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The ARRIVE guidelines 2.0: updated guidelines for reporting animal research . The Journal of Physiology vol. 598 , ( 18 ) 3793 - 3801 .
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The ARRIVE guidelines 2.0: updated guidelines for reporting animal research . BMJ Open Science vol. 4 , ( 1 )
Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM, Ahluwalia A ( 2020 ) . The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway . Pharmacological reviews vol. 72 , ( 3 ) 692 - 766 .
Cirino G, Ahluwalia A ( 2020 ) . The many mechanisms of action of Chloroquine: to use or not to use (in COVID‐19) that is the question . British Journal of Pharmacology vol. 177 , ( 15 ) 3361 - 3362 .
Izzo AA, Teixeira M, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Ji Y et al. ( 2020 ) . A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: Reproducibility of natural product research . British Journal of Pharmacology vol. 177 , ( 10 ) 2169 - 2178 .
Lau CWZ, Hamers AJP, Rathod KS, Shabbir A, Cooper J, Primus CP, Davies C, Mathur A et al. ( 2020 ) . Randomised, double-blind, placebo-controlled clinical trial investigating the effects of inorganic nitrate in hypertension-induced target organ damage: Protocol of the NITRATE-TOD study in the UK . BMJ Open vol. 10 , ( 1 )
George CH, Alexander SPH, Cirino G, Docherty JR, Hoyer D, Insel PA, Izzo AA, Ji Y et al. ( 2020 ) . The BJP expects authors to share data . British Journal of Pharmacology vol. 176 , ( 24 ) 4595 - 4598 .
Dreyer G, Kieswich J, Harwood S, Ahluwalia A, Yaqoob MM ( 2019 ) . Ergocalciferol improves endothelial vasodilatory and vasoconstrictor function in an in vivo model of mild uraemia . Bioscience Reports vol. 39 , ( 12 )
( 2019 ) . Natural Mutations of the Human Xdh Impact upon the Nitric Oxide-generating Capacity of Xanthine Oxidoreductase . Free Radical Biology and Medicine . vol. 145 ,
Ingram JR, Ahluwalia A ( 2019 ) . The pharmacology of itch . British Journal of Pharmacology vol. 176 , ( 23 ) 4419 - 4420 .
Ingram JR, Ahluwalia A ( 2019 ) . The pharmacology of itch . British Journal of Dermatology
Jones DA, Mathur A, Ahluwalia A ( 2019 ) . Letter by Jones et al regarding article, “Optimized treatment of ST-elevation myocardial infarction” . Circulation Research vol. 125 , ( 6 ) E29 - E29 .
Docherty JR, Stanford SC, Panettieri RA, Alexander SPH, Cirino G, George CH, Hoyer D, Izzo AA et al. ( 2019 ) . Sex: A change in our guidelines to authors to ensure that this is no longer an ignored experimental variable . British Journal of Pharmacology vol. 176 , ( 21 ) 4081 - 4086 .
du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC et al. ( 2019 ) . Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019 .
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2019 ) . The ARRIVE guidelines 2019: updated guidelines for reporting animal research .
Jones DA, Rathod KS, Williamson A, Mand K, Harrington D, Andiapen M, van Eijl S, Westwood M et al. ( 2019 ) . Corrigendum to “The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction” [Int. J. Cardiol. 266 (2018) 1–6] . International Journal of Cardiology vol. 292 ,
Guzik TJ, Ahluwalia A ( 2019 ) . Plan S: in Service or Disservice to Society? . European Heart Journal vol. 40 , ( 12 ) 949 - 952 .
Guzik TJ, Ahluwalia A ( 2019 ) . Plan S: In service or disservice to society? . British Journal of Pharmacology vol. 176 , ( 6 ) 753 - 756 .
Ahluwalia A ( 2018 ) . P2 Inorganic Nitrate as a Regulator of Vascular Function . Free Radical Biology and Medicine . vol. 128 ,
Hamers AJP, Ahluwalia A ( 2017 ) . Arachidonic acid metabolites induce TRPV1‐mediated inflammation . The FASEB Journal . vol. 31 ,
Jones DA, Rathod KS, Williamson A, Harrington D, Andiapen M, van Eijl S, Westwood M, Antoniou S et al. ( 2018 ) . The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction . International Journal of Cardiology vol. 266 , 1 - 6 .
Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A, Ahluwalia A ( 2018 ) . P2564Sodium nitrite-mediated cardioprotection in primary percutaneous coronary intervention for ST-elevation myocardial infarction: a cost-effectiveness analysis . European Heart Journal vol. 39 , ( suppl_1 )
Curtis MJ, Ashton JC, Moon LDF, Ahluwalia A ( 2018 ) . Clarification of the basis for the selection of requirements for publication in the British Journal of Pharmacology . British Journal of Pharmacology vol. 175 , ( 18 ) 3633 - 3635 .
AHLUWALIA A, JONES D, MATHUR A ( 2018 ) . Sodium Nitrite-Mediated Cardioprotection in Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: A Cost-Effectiveness Analysis . Journal of Cardiovascular Pharmacology and Therapeutics
Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, Watson DS, Barnes MR et al. ( 2018 ) . Sex differences in the nitrate-nitrite-NO• pathway: Role of oral nitrate-reducing bacteria . Free Radical Biology and Medicine vol. 126 , 113 - 121 .
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J et al. ( 2018 ) . Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis . FASEB Jfj201701303R - fj201701303R .
Ahluwalia A, Cirino G ( 2018 ) . Launch of mini‐reviews in hot topics . British Journal of Pharmacology vol. 175 , ( 13 ) 2537 - 2537 .
du Sert NP, Hurst V, Ahluwalia A, Alam S, Altman DG, Avey MT, Baker M, Browne W et al. ( 2018 ) . Revision of the ARRIVE guidelines: rationale and scope . BMJ Open Science vol. 2 , ( 1 )
Yellon DM, He Z, Khambata R, Ahluwalia A, Davidson SM ( 2018 ) . The GTN patch: a simple and effective new approach to cardioprotection? . Basic Research in Cardiology vol. 113 , ( 3 )
Curtis MJ, Alexander S, Cirino G, Docherty JR, George CH, Giembycz MA, Hoyer D, Insel PA et al. ( 2018 ) . Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers . British Journal of Pharmacology vol. 175 , ( 7 ) 987 - 993 .
AHLUWALIA A ( 2018 ) . Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology . British Journal of Pharmacology vol. 175 , 407 - 411 .
Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A, Ahluwalia A ( 2018 ) . Sodium nitrite-mediated cardioprotection in primary percutaneous coronary intervention for ST-elevation myocardial infarction: a cost-effectiveness analysis . EUROPEAN HEART JOURNAL . vol. 39 , 504 - 504 .
Osborne NJ, Ritskes-Hoitinga M, Ahluwahlia A, Alam S, Brown M, Henderson H, de Leeuw W, Marsh J et al. ( 2017 ) . Letter to the editor - round table unites to tackle culture change in an effort to improve animal research reporting . BMC Veterinary Research vol. 13 , ( 1 )
Kapil V ( 2017 ) . Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017 . BMC Pharmacol Toxicol vol. 18 , ( Suppl 1 ) 64 - 64 .
Ahluwalia A, Jones MK, Hoa N, Tarnawski AS ( 2017 ) . NGF protects endothelial cells from indomethacin-induced injury through activation of mitochondria and upregulation of IGF-1 . Cellular Signalling vol. 40 , 22 - 29 .
Rathod KS, Hamshere S, Khambata RS, Andiapen M, Westwood M, Mathur A, Ahluwalia A, Jones DA ( 2017 ) . Combined analysis of the safety of intra-coronary drug delivery during primary percutaneous coronary intervention for acute myocardial infarction: A study of three clinical trials . JRSM Cardiovasc Dis vol. 6 , 2048004017725988 - 2048004017725988 .
George CH, Stanford SC, Alexander S, Cirino G, Docherty JR, Giembycz MA, Hoyer D, Insel PA et al. ( 2017 ) . Updating the guidelines for data transparency in the British Journal of Pharmacology – data sharing and the use of scatter plots instead of bar charts . British Journal of Pharmacology vol. 174 , ( 17 ) 2801 - 2804 .
Campo G, Pavasini R, Morciano G, Lincoff MA, Gibson MC, Kitakaze M, Lonborg J, Ahluwalia A et al. ( 2017 ) . Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention . Data in Brief vol. 14 , 197 - 205 .
Yuzugulen J, Douthwaite JA, Wood EG, Villar IC, Patel NSA, Jegard J, Gaertner H, Rossitto-Borlat I et al. ( 2017 ) . Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1 . Sci Rep vol. 7 , ( 1 ) 4956 - 4956 .
Campo G, Pavasini R, Morciano G, Lincoff AM, Gibson CM, Kitakaze M, Lonborg J, Ahluwalia A et al. ( 2017 ) . Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials . International Journal of Cardiology vol. 244 , 59 - 66 .
Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al. ( 2017 ) . Sex differences in the inflammatory response and inflammation-induced vascular dysfunction . LANCET . Conference: FASEB vol. 389 , 20 - 20 .
AHLUWALIA A ( 2017 ) . The anti-inflammatory actions of inorganic nitrate stabilise the atherosclerotic plaque . Proceedings of the National Academy of Sciences of USA
Jones DA, Rathod KS, Ahluwalia A ( 2017 ) . Chapter 15 Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation . Nitric Oxide , Elsevier
Gee LC, Massimo G, Rathod KS, Fernandes D, Ahluwalia A ( 2017 ) . Effects of Dietary Nitrate on Blood Pressure-dependent and Independent Cardiac Dysfunction . CIRCULATION . vol. 136 ,
Jones DA, Rathod KS, Ahluwalia A ( 2017 ) . Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation . Nitric Oxide: Biology and Pathobiology: Third Edition ,
Rathod KS, Jones DA, Van-Eijl TJA, Tsang H, Warren H, Hamshere SM, Kapil V, Jain AK et al. ( 2016 ) . Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study . BMJ Open vol. 6 , ( 12 )
AHLUWALIA A ( 2016 ) . Accelerated resolution underlies sex differences in the inflammatory response in human . Journal of Clinical Investigation vol. 127 , ( 1 ) 169 - 182 .
Ahluwalia A, Jones MK, Brzozowski T, Tarnawski AS ( 2016 ) . Nerve growth factor is critical requirement for in vitro angiogenesis in gastric endothelial cells . AJP Gastrointestinal and Liver Physiology vol. 311 , ( 5 ) g981 - g987 .
Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A ( 2016 ) . ACTIVATION OF TRPV1 BY 12(S)-HPETE AND 20-HETE RELEASES CGRP AND PROTECTS THE HEART AGAINST THE CARDIAC DYSFUNCTION CAUSED BY LPS . SHOCK . Conference: Exp Biology 2016 vol. 46 , 31 - 32 .
Jones DA, Khambata RS, Andiapen M, Rathod KS, Mathur A, Ahluwalia A ( 2016 ) . Intracoronary nitrite suppresses the inflammatory response following primary percutaneous coronary intervention . Heart
Hoa NT, Ge L, Martini F, Chau V, Ahluwalia A, Kruse CA, Jadus MR ( 2016 ) . Temozolomide induces the expression of the glioma Big Potassium (gBK) ion channel, while inhibiting fascin-1 expression: possible targets for glioma therapy . Expert Opinion on Therapeutic Targets vol. 20 , ( 10 ) 1155 - 1167 .
Ahluwalia A, Gladwin M, Coleman GD, Hord N, Howard G, Kim‐Shapiro DB, Lajous M, Larsen FJ et al. ( 2016 ) . Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop . Journal of the American Heart Association vol. 5 , ( 7 )
Samarasena JB, Ahluwalia A, Shinoura S, Choi KD, Lee JG, Chang KJ, Tarnawski AS ( 2016 ) . In vivo imaging of porcine gastric enteric nervous system using confocal laser endomicroscopy &molecular neuronal probe . Journal of Gastroenterology and Hepatology vol. 31 , ( 4 ) 802 - 807 .
Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A ( 2016 ) . Activation of TRPV1 by 12(s)-HpETE and 20-HETE Releases CGRP and Protects the Heart Against the Cardiac Dysfunction Caused by LPS . FASEB JOURNAL . Conference: Exp Biology (FASEB) 2016 vol. 30 ,
Khambata RS, Ghosh SM, Rathod KS, Thevathasan T, Ahluwalia A ( 2016 ) . Dietary Nitrate Supresses Leukocyte Recruitment and Activation in Apolipoprotein E Knockout Mice . The FASEB Journal . vol. 30 ,
Filomena F, Khambata R, Ahluwalia A ( 2016 ) . Dietary nitrate suppresses platelet reactivity in Apolipoprotein E Knockout Mice . The FASEB Journal . vol. 30 ,
Rathod KS, Siddiqui U, Hartley A, Khambata RS, Ahluwalia A ( 2016 ) . Investigation of the influence of sex on cantharidin‐induced inflammation in healthy volunteers . The FASEB Journal . vol. 30 ,
Ivanova E, Coroiu A, Ahluwalia A, Alexandrov E, Lafreniere KD ( 2016 ) . Preliminary Findings on the Association Between Symptoms of Depression and Adherence to Antiretroviral Therapy in Individuals Born Inside Versus Outside of Canada . Journal of the Association of Nurses in AIDS Care vol. 27 , ( 4 ) 512 - 523 .
Aguinaldo JP, Ahluwalia A, Hambly K, Koornstra J, Rankin B, Roesslein K ( 2016 ) . Needs and Supports in Transitional Housing for People Living with HIV/AIDS in Ontario, Canada . Journal of Social Service Research vol. 42 , ( 3 ) 352 - 362 .
Gee LC, Ahluwalia A ( 2016 ) . Dietary Nitrate Lowers Blood Pressure: Epidemiological, Pre-clinical Experimental and Clinical Trial Evidence . Current Hypertension Reports vol. 18 , ( 2 )
Rathod KS, Velmurugan S, Ahluwalia A ( 2016 ) . A 'green' diet-based approach to cardiovascular health? Is inorganic nitrate the answer? . Molecular Nutrition and Food Research vol. 60 , ( 1 ) 185 - 202 .
Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V et al. ( 2015 ) . Dietary nitrate improves vascular function in patients with hypercholesterolemia: a randomized, double-blind, placebo-controlled study 1–3 . American Journal of Clinical Nutrition vol. 103 , ( 1 ) 25 - 38 .
Fernandes D, Khambata R, Ahluwalia A ( 2015 ) . Abstract 10110: Effects of Inorganic Nitrate on Endothelial Dysfunction Induced by Periodontitis . Circulation vol. 132 , ( suppl_3 )
Jandhyala DM, Ahluwalia A, Schimmel JJ, Rogers AB, Leong JM, Thorpe CM ( 2015 ) . Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation . Infection and Immunity vol. 84 , ( 1 ) 138 - 148 .
Rathod KS, Velmurugan S, Ahluwalia A ( 2015 ) . A ‘green’ diet‐based approach to cardiovascular health? Is inorganic nitrate the answer? . Molecular Nutrition & Food Research vol. 60 , ( 1 ) 185 - 202 .
Samarasena JB, Tarnawski AS, Ahluwalia A, Shinoura S, Choi KD, Lee JG, Chang KJ ( 2015 ) . EUS-guided in vivo imaging of the porcine esophageal enteric nervous system by using needle-based confocal laser endomicroscopy . Gastrointestinal Endoscopy vol. 82 , ( 6 ) 1116 - 1120 .
( 2015 ) . Erratum . British Journal of Pharmacology vol. 172 , ( 18 ) 4600 - 4600 .
Curtis MJ, Bond RA, Spina D, Ahluwalia A, Alexander SPA, Giembycz MA, Gilchrist A, Hoyer D et al. ( 2015 ) . Experimental design and analysis and their reporting: new guidance for publication in BJP . British Journal of Pharmacology vol. 172 , ( 14 ) 3461 - 3471 .
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2015 ) . Erratum: Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex (Free Radical Biology and Medicine (2013) 65 (1521-1532)) . Free Radical Biology and Medicine vol. 84 ,
Tolstanova G, Deng X, Ahluwalia A, Paunovic B, Prysiazhniuk A, Ostapchenko L, Tarnawski A, Sandor Z et al. ( 2015 ) . Role of Dopamine and D2 Dopamine Receptor in the Pathogenesis of Inflammatory Bowel Disease . Digestive Diseases and Sciences vol. 60 , ( 10 ) 2963 - 2975 .
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2015 ) . Erratum to “Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex” [Free Radic. Biol. Med. 65 (2013) 1521–1532] . Free Radical Biology and Medicine vol. 84 ,
Khambata RS, Ghosh SM, Ahluwalia A ( 2015 ) . “Repurposing” of Xanthine Oxidoreductase as a Nitrite Reductase: A New Paradigm for Therapeutic Targeting in Hypertension . Antioxidants & Redox Signaling vol. 23 , ( 4 ) 340 - 353 .
Macé V, Ahluwalia A, Coron E, Le Rhun M, Boureille A, Bossard C, Mosnier J, Matysiak‐Budnik T et al. ( 2015 ) . Confocal laser endomicroscopy: A new gold standard for the assessment of mucosal healing in ulcerative colitis . Journal of Gastroenterology and Hepatology vol. 30 , ( S1 ) 85 - 92 .
Lara J, Ashor AW, Oggioni C, Ahluwalia A, Mathers JC, Siervo M ( 2015 ) . Effects of inorganic nitrate and beetroot supplementation on endothelial function: a systematic review and meta-analysis . European Journal of Nutrition vol. 55 , ( 2 ) 451 - 459 .
Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A ( 2015 ) . Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study . Hypertension vol. 65 , ( 2 ) 320 - 327 .
Velmurugan S, Ghosh SM, Khambata RS, Van Eijl S, Robertson A, Chowdhury TA, Ahluwalia A ( 2015 ) . Acute administration of dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia . EUROPEAN HEART JOURNAL . vol. 36 , 257 - 257 .
Fernandes D, Khambata R, Ahluwalia A ( 2015 ) . Effects of Inorganic Nitrate on Endothelial Dysfunction Induced by Periodontitis . CIRCULATION . vol. 132 ,
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, Van Eijl S, Webb AJ et al. ( 2015 ) . Randomized phase 2 trial of intracoronary nitrite during acute myocardial infarction . Circulation Research vol. 116 , ( 3 ) 437 - 447 .
Tarnawski AS, Ahluwalia A, Jones MK ( 2014 ) . Angiogenesis in gastric mucosa: An important component of gastric erosion and ulcer healing and its impairment in aging . Journal of Gastroenterology and Hepatology vol. 29 , ( S4 ) 112 - 123 .
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, van Eijl S, Webb AJ et al. ( 2014 ) . Randomized Phase 2 Trial of Intracoronary Nitrite During Acute Myocardial Infarction . Circulation Research vol. 116 , ( 3 ) 437 - 447 .
Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A ( 2014 ) . Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients . Hypertension vol. 65 , ( 2 ) 320 - 327 .
Jones DA, Pellaton C, Velmurugan S, Andiapen M, Antoniou S, Van Eijl S, Westwood MA, Webb AJ et al. ( 2014 ) . P141 The safety and efficacy of intra-coronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): A single centre, randomised, double-blind controlled trial . Nitric Oxide vol. 42 , 127 - 128 .
Rathod K, Ghosh S, Khambata R, Ahluwalia A ( 2014 ) . P175 Xanthine oxidoreductase in atherosclerotic mice: Determination of expression and nitrite reductase activity . Nitric Oxide vol. 42 ,
Velmurugan S, Ghosh S, Khambata R, Van Eijl S, Robertson A, Chowdhury T, Ahluwalia A ( 2014 ) . P200 Dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia . Nitric Oxide vol. 42 ,
Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ et al. ( 2014 ) . Endothelial C-type natriuretic peptide maintains vascular homeostasis . J Clin Invest vol. 124 , ( 9 ) 4039 - 4051 .
Ahluwalia A, Baatar D, Jones MK, Tarnawski AS ( 2014 ) . Novel mechanisms and signaling pathways of esophageal ulcer healing: the role of prostaglandin EP2 receptors, cAMP, and pCREB . AJP Gastrointestinal and Liver Physiology vol. 307 , ( 6 ) g602 - g610 .
Kapil V, Weitzberg E, Lundberg JO, Ahluwalia A ( 2014 ) . Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health . Nitric Oxide - Biology and Chemistry vol. 38 , ( 1 ) 45 - 57 .
Kapil V, Weitzberg E, Lundberg JO, Ahluwalia A ( 2014 ) . Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health . Nitric Oxide vol. 38 , 45 - 57 .
Khomenko T, Deng X, Ahluwalia A, Tarnawski A, Patel KN, Sandor Z, Szabo S ( 2014 ) . STAT3 and Importins Are Novel Mediators of Early Molecular and Cellular Responses in Experimental Duodenal Ulceration . Digestive Diseases and Sciences vol. 59 , ( 2 ) 297 - 306 .
Ghosh S, Khambata R, Ahluwalia A ( 2014 ) . DIETARY INORGANIC NITRATE REDUCES INFLAMMATORY CELL RECRUITMENT IN MICE . BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY . vol. 115 , 17 - 17 .
Velmurugan S, Ghosh SM, Khambata RS, Robertson AC, Van Eijl TJA, Chowdhury TA, Ahluwalia A ( 2014 ) . Dietary nitrate improves endothelial function, vascular stiffness and modifies platelet markers of atherogenesis in hypercholesterolemia . EUROPEAN HEART JOURNAL . vol. 35 , 1047 - 1047 .
Tarnawski AS, Ahluwalia A, Jones MK ( 2014 ) . Increased susceptibility of aging gastric mucosa to injury: The mechanisms and clinical implications . World Journal of Gastroenterology vol. 20 , ( 16 ) 4467 - 4482 .
Jones DA, Pellaton C, Velmurugan S, Andiapen M, Antoniou S, Van Eijl S, Westwood M, Parmar MK et al. ( 2014 ) . The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): a single centre, randomised, double-blind controlled trial . EUROPEAN HEART JOURNAL . vol. 35 , 1154 - 1155 .
Ahluwalia A, Jones MK, Matysiak-Budnik T, Tarnawski AS ( 2014 ) . VEGF and colon cancer growth beyond angiogenesis: does VEGF directly mediate colon cancer growth via a non-angiogenic mechanism? . Current Pharmaceutical Design vol. 20 , ( 7 ) 1041 - 1044 .
Ahluwalia A, Jones MK, Tarnawski AS ( 2013 ) . Key role of endothelial importin-α in VEGF expression and gastric angiogenesis: novel insight into aging gastropathy . AJP Gastrointestinal and Liver Physiology vol. 306 , ( 4 ) g338 - g345 .
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2013 ) . Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex . Free Radic Biol Med vol. 65 , 1521 - 1532 .
Yuzugulen J, Wood EG, Villar IC, Douthwaite JA, Patel NSAI, Jegard J, Montoya A, Cutillas P et al. ( 2013 ) . Characterisation of the “Endothelin-Like Domain Peptide” (ELDP) co-synthesised with Endothelin-1 from the EDN1 gene . Life Sciences vol. 93 , ( 25-26 )
Ahluwalia A, Gokulan K, Nath I, Rao DN ( 2013 ) . Modification of Delivery System Enhances MHC Nonrestricted Immunogenicity of V3 Loop Region of HIV‐1 gp120 . Microbiology and Immunology vol. 41 , ( 10 ) 779 - 784 .
Bubb KJ, Wen H, Panayiotou CM, Finsterbusch M, Khan FJ, Chan MV, Priestley JV, Baker MD et al. ( 2013 ) . Activation of neuronal transient receptor potential vanilloid 1 channel underlies 20-hydroxyeicosatetraenoic acid-induced vasoactivity: role for protein kinase A . Hypertension vol. 62 , ( 2 ) 426 - 433 .
Ahluwalia A, Jones MK, Szabo S, Tarnawski AS ( 2013 ) . Aberrant, ectopic expression of VEGF and VEGF receptors 1 and 2 in malignant colonic epithelial cells. Implications for these cells growth via an autocrine mechanism . Biochemical and Biophysical Research Communications vol. 437 , ( 4 ) 515 - 520 .
Ahluwalia A, Jones MK, Deng X, Sandor Z, Szabo S, Tarnawski AS ( 2013 ) . An imbalance between VEGF and endostatin underlies impaired angiogenesis in gastric mucosa of aging rats . AJP Gastrointestinal and Liver Physiology vol. 305 , ( 4 ) g325 - g332 .
Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S et al. ( 2013 ) . Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential . Hypertension vol. 61 , ( 5 ) 1091 - 1102 .
Kapil V, Haydar SMA, Pearl V, Lundberg JO, Weitzberg E, Ahluwalia A ( 2013 ) . Physiological role for nitrate-reducing oral bacteria in blood pressure control . Free Radic Biol Med vol. 55 , 93 - 100 .
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2013 ) . Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex . Free Radical Biology and Medicine vol. 65 , 1521 - 1532 .
Rousselle A, Qadri F, Leukel L, Yilmaz R, Fontaine J-F, Sihn G, Bader M, Ahluwalia A et al. ( 2013 ) . CXCL5 limits macrophage foam cell formation in atherosclerosis . JOURNAL OF CLINICAL INVESTIGATION vol. 123 , ( 3 ) 1343 - 1347 .
Martin K, Perretti M, Ahluwalia A ( 2013 ) . Kinin B1 receptor regulates inflammatory cell recruitment during low laminar shear stress . FASEB JOURNAL . vol. 27 ,
Ahluwalia A, Hobbs AJ ( 2013 ) . Letter by Ahluwalia and Hobbs Regarding Article, "Nitrate-Nitrite-Nitric Oxide Pathway in Pulmonary Arterial Hypertension Therapeutics" . CIRCULATION vol. 127 , ( 2 ) E275 - E275 .
Ghosh SM, Kapil V, Bubb K, Fuentes-Calvo I, Ahluwalia A ( 2013 ) . Mechanisms underlying nitrite reduction in hypertension: Role for erythrocytic xanthine oxidoreductase . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 31 , S24 - S25 .
Jones DA, Khambata RS, Mathur A, Ahluwalia A ( 2013 ) . Sodium nitrite promotes the viability and proliferation of endothelial cells but inhibits the growth of smooth muscle cells under hypoxia . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 31 , S22 - S22 .
Jones DA, Andiapen M, Van-Eijl TJA, Webb AJ, Antoniou S, Schilling RJ, Ahluwalia A, Mathur A ( 2013 ) . The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): study protocol of a randomised controlled trial . BMJ Open vol. 3 , ( 4 )
Yuzugulen J, Wood EG, Douthwaite JA, Villar IC, Patel NS, Jegard J, Montoya A, Cutillas P et al. ( 2012 ) . Abstract 18898: Characterization of Proendothelin-1 Derived Peptides Identifies a Co-secreted Modulator of ET-1 Vasoconstriction, and Provides Insights for Biomarker Measurements . Circulation vol. 126 , ( suppl_21 )
Chan MV, Bubb KJ, Noyce A, Villar IC, Duchene J, Hobbs AJ, Scotland RS, Ahluwalia A ( 2012 ) . Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation . Br J Pharmacol vol. 167 , ( 4 ) 805 - 817 .
Bubb KJ, Khambata RS, Ahluwalia A ( 2012 ) . Sexual dimorphism in rodent models of hypertension and atherosclerosis . Br J Pharmacol vol. 167 , ( 2 ) 298 - 312 .
Perretti M, Ahluwalia A, Harris JG, Harris HJ, Wheller SK, Flower RJ ( 2012 ) . Acute inflammatory response in the mouse: exacerbation by immunoneutralization of lipocortin 1 . British Journal of Pharmacology vol. 117 , ( 6 ) 1145 - 1154 .
Ahluwalia A, Maggi CA, Santicioli P, Lecci A, Giuliani S ( 2012 ) . Characterization of the capsaicin‐sensitive component of cyclophosphamide‐induced inflammation in the rat urinary bladder . British Journal of Pharmacology vol. 111 , ( 4 ) 1017 - 1022 .
Ahluwalia A, Giuliani S, Maggi CA ( 2012 ) . Demonstration of a ‘septide‐sensitive’ inflammatory response in rat skin . British Journal of Pharmacology vol. 116 , ( 4 ) 2170 - 2174 .
Ahluwalia A, Flower RJ ( 2012 ) . Investigations into the mechanism of vasoconstrictor action of the topical steroid betamethasone‐17‐valerate in the rat . British Journal of Pharmacology vol. 108 , ( 2 ) 544 - 548 .
Ahluwalia A, Peers SH, Flower RJ ( 2012 ) . Steroid inhibition of oedema formation in the rat skin . British Journal of Pharmacology vol. 106 , ( 3 ) 628 - 631 .
Baliga RS, Milsom AB, Ghosh SM, Trinder SL, Macallister RJ, Ahluwalia A, Hobbs AJ ( 2012 ) . Dietary nitrate ameliorates pulmonary hypertension: cytoprotective role for endothelial nitric oxide synthase and xanthine oxidoreductase . Circulation vol. 125 , ( 23 ) 2922 - 2932 .
Bahra M, Kapil V, Pearl V, Ghosh S, Ahluwalia A ( 2012 ) . Inorganic nitrate ingestion improves vascular compliance but does not alter flow-mediated dilatation in healthy volunteers . Nitric Oxide vol. 26 , ( 4 ) 197 - 202 .
Baliga RS, Milsom AB, Trinder SL, Ghosh S, MacAllister RJ, Ahluwalia A, Hobbs AJ ( 2012 ) . Dietary Nitrate: A Novel Therapy For Pulmonary Hypertension . Conference: B63. EXPERIMENTAL MODELS IN PULMONARY HYPERTENSION Ia3413 - a3413 .
Wen H, Östman J, Bubb KJ, Panayiotou C, Priestley JV, Baker MD, Ahluwalia A ( 2012 ) . 20-Hydroxyeicosatetraenoic acid (20-HETE) is a novel activator of transient receptor potential vanilloid 1 (TRPV1) channel . J Biol Chem vol. 287 , ( 17 ) 13868 - 13876 .
Colom B, Poitelon Y, Huang W, Woodfin A, Averill S, Del Carro U, Zambroni D, Brain SD et al. ( 2012 ) . Schwann cell-specific JAM-C-deficient mice reveal novel expression and functions for JAM-C in peripheral nerves . FASEB J vol. 26 , ( 3 ) 1064 - 1076 .
Bubb KJ, Ahluwalia A ( 2012 ) . 20-HETE-induced activation of TRPV1: a novel pathway influencing blood pressure and coronary resistance . CARDIOVASCULAR RESEARCH . vol. 93 , S75 - S76 .
Moyes AJ, Khambata RS, Ahluwalia A, Hobbs AJ ( 2012 ) . Accelerated Atherogenesis and Diminished Vascular Integrity in Mice Lacking Endothelial C-Type Natriuretic Peptide . CIRCULATION vol. 126 , ( 21 )
Yuzugulen J, Wood EG, Douthwaite JA, Villar IC, Patel NS, Jegard J, Montoya A, Cutillas P et al. ( 2012 ) . Characterization of Proendothelin-1 Derived Peptides Identifies a Co-secreted Modulator of ET-1 Vasoconstriction, and Provides Insights for Biomarker Measurements . CIRCULATION vol. 126 , ( 21 )
Velmurugan S, Pearl V, Ghosh SM, Davies S, Khambata RS, van Eijl S, Kapil V, Ahluwalia A ( 2012 ) . Inorganic Nitrate Attenuates Platelet Reactivity in Healthy Males but not Females: Role of the Erythrocyte and Cyclic GMP . CIRCULATION vol. 126 , ( 21 )
Bahra M, Kapil V, Pearl V, Ghosh S, Ahluwalia A ( 2012 ) . Inorganic nitrate ingestion decreases blood pressure and improves vascular compliance in healthy volunteers . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 73 , 1004 - 1005 .
Velmurugan S, Pearl V, Davies S, Bahra M, Ghosh S, Kapil V, Ahluwalia A ( 2012 ) . Inorganic nitrate supplementation attenuates platelet reactivity in healthy male volunteers . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 27 , S27 - S28 .
Ghosh S, Kapil V, Bubb K, Fuentes I, Ahluwalia A ( 2012 ) . Mechanisms underlying nitrite reduction in hypertension: Role for erythrocyte xanthine oxidoreductase . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 27 , S30 - S31 .
Fuentes-Calvo I, Bubb K, Ghosh S, Ahluwalia A ( 2012 ) . Nitrite induced-hypotension is enhanced in hypertension: Role for xanthine oxidoreductase . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 27 , S31 - S31 .
Khambata R, Ghosh S, Ahluwalia A ( 2012 ) . Nitrite superfusion reduces leukocyte-endothelial interactions in the mouse cremaster model . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 27 , S15 - S15 .
Stone SM, Thorpe CM, Ahluwalia A, Rogers AB, Obata F, Vozenilek A, Kolling GL, Kane AV et al. ( 2012 ) . Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib . Frontiers in Cellular and Infection Microbiology vol. 2 ,
Duchene J, Ahluwalia A ( 2011 ) . Kallikrein-kinin system in inflammation . 261 - 272 .
Duchene J, Ahluwalia A ( 2011 ) . 16 Kallikrein-kinin system in infl ammation . Kinins , De Gruyter
Paunovic B, Deng X, Khomenko T, Ahluwalia A, Tolstanova G, Tarnawski A, Szabo S, Sandor Z ( 2011 ) . Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats . Journal of Pharmacology and Experimental Therapeutics vol. 339 , ( 2 ) 430 - 437 .
Rourke SB, Sobota M, Tucker R, Bekele T, Gibson K, Greene S, Price C, Koornstra JJJ et al. ( 2011 ) . Social determinants of health associated with hepatitis C co-infection among people living with HIV: results from the Positive Spaces, Healthy Places study . Open Medicine vol. 5 , ( 3 ) e120 - e131 .
Florkiewicz RZ, Ahluwalia A, Sandor Z, Szabo S, Tarnawski AS ( 2011 ) . Gastric mucosal injury activates bFGF gene expression and triggers preferential translation of high molecular weight bFGF isoforms through CUG-initiated, non-canonical codons . Biochemical and Biophysical Research Communications vol. 409 , ( 3 ) 494 - 499 .
Velmurugan S, Kapil V, McKnight AHO, Aboud Z, Davies S, Milsom AB, Pearl V, Liverani E et al. ( 2011 ) . Dietary nitrate attenuates platelet reactivity: Role of the erythrocyte and influence of sex . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 24 , S35 - S36 .
Monette LE, Rourke SB, Gibson K, Bekele TM, Tucker R, Greene S, Sobota M, Koornstra J et al. ( 2011 ) . Inequalities in Determinants of Health Among Aboriginal and Caucasian Persons Living With HIV/AIDS in Ontario: Results From the Positive Spaces, Healthy Places Study . Canadian Journal of Public Health vol. 102 , ( 3 ) 215 - 219 .
Kapil V, Syed M, Pearl V, Allaker R, Ahluwalia A ( 2011 ) . Interruption of the entero-salivary metabolism of nitrate to nitrite increases blood pressure in healthy volunteers . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 24 , S35 - S35 .
Villar IC, Scotland RS, Khambata RS, Chan M, Duchene J, Sampaio AL, Perretti M, Hobbs AJ et al. ( 2011 ) . Suppression of endothelial P-selectin expression contributes to reduced cell trafficking in females: an effect independent of NO and prostacyclin . Arterioscler Thromb Vasc Biol vol. 31 , ( 5 ) 1075 - 1083 .
Kapil V, Benjamin N, Hobbs A, Ahluwalia A ( 2011 ) . Response to Inorganic Nitrate for Blood Pressure Lowering? . HYPERTENSION vol. 57 , ( 2 ) E3 - E3 .
Kapil V, Webb AJ, Ahluwalia A ( 2010 ) . Inorganic nitrate and the cardiovascular system . Heart vol. 96 , ( 21 ) 1703 - 1709 .
Yamashiro K, Milsom AB, Duchene J, Panayiotou C, Urabe T, Hattori N, Ahluwalia A ( 2010 ) . Alterations in nitric oxide and endothelin-1 bioactivity underlie cerebrovascular dysfunction in ApoE-deficient mice . J Cereb Blood Flow Metab vol. 30 , ( 8 ) 1494 - 1503 .
Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V et al. ( 2010 ) . Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO . Hypertension vol. 56 , ( 2 ) 274 - 281 .
Kapil V, Maleki-Toyserkani S, Rehman F, Arghandawi S, Pearl V, Milsom A, Benjamin N, Hobbs A et al. ( 2010 ) . Oral inorganic nitrate lowers blood pressure in healthy male, but not female, volunteers, via bioconversion to nitrite . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 70 , 285 - 285 .
Tarnawski AS, Pai R, Tanigawa T, Matysiak-Budnik T, Ahluwalia A ( 2010 ) . PTEN silencing reverses aging-related impairment of angiogenesis in microvascular endothelial cells . Biochemical and Biophysical Research Communications vol. 394 , ( 2 ) 291 - 296 .
Milsom AB, Patel NSA, Mazzon E, Tripatara P, Storey A, Mota-Filipe H, Sepodes B, Webb AJ et al. ( 2010 ) . Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischemia-reperfusion injury in mice . NITRIC OXIDE-BIOL CH vol. 22 , ( 2 ) 141 - 148 .
PERRETTI M, AHLUWALIA A ( 2010 ) . The Microcirculation and Inflammation: Site of Action for Glucocorticoids . Microcirculation vol. 7 , ( 3 ) 147 - 161 .
( 2010 ) . A Role of Matrix Metalloproteinase-8 in Atherosclerosis: Correction . Circulation Research vol. 106 , ( 1 )
Webb A, Ahluwalia A ( 2010 ) . Chapter 17 Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System . Nitric Oxide , Elsevier
WEBB A, Webb A, Ahluwalia A ( 2010 ) . Mechanisms of Nitrite Reduction in Ischemia in the Cardiovascular System . Nitric Oxide Biology and Pathobiology , Editors: Ignarro, LJ , Edition. 2 , Academic Press
Webb AJ, Ahluwalia A ( 2010 ) . Mechanisms of nitrite reduction in ischemia in the cardiovascular system . Nitric Oxide: Biology and pathobiology , Editors: Ignarro, L , Edition. second , Elsevier ( USA ),
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Vessillier S, Duchene J, Vojnovic I, Cipollone F, Mezzetti A, White S, Ahluwalia A, Bishop-Bailey D et al. ( 2009 ) . THERAPEUTIC TARGETTING OF ATHEROSCLEROTIC PLAQUES WITH LATENT INTERLEUKIN-4 . HEART . vol. 95 ,
Duchene J, Cayla C, Vessillier S, Scotland R, Yamashiro K, Lecomte F, Syed I, Vo P et al. ( 2009 ) . Laminar shear stress regulates endothelial kinin B1 receptor expression and function: potential implication in atherogenesis . Arterioscler Thromb Vasc Biol vol. 29 , ( 11 ) 1757 - 1763 .
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Greene S, Ahluwalia A, Watson J, Tucker R, Rourke SB, Koornstra J, Sobota M, Monette L et al. ( 2009 ) . Between skepticism and empowerment: the experiences of peer research assistants in HIV/AIDS, housing and homelessness community‐based research . International Journal of Social Research Methodology vol. 12 , ( 4 ) 361 - 373 .
Greene S, Tucker R, Rourke SB, Monette L, Koornstra J, Sobota M, Byers S, Hwang S et al. ( 2009 ) . “Under My Umbrella”: The housing experiences of HIV positive parents who live with and care for their children in Ontario . Archives of Women's Mental Health vol. 13 , ( 3 ) 223 - 232 .
Kapil V, Rehman F, Arghandawi S, Milsom A, Benjamin N, Hobbs A, MacAllister R, Webb A et al. ( 2009 ) . BLOOD PRESSURE LOWERING EFFECTS OF ORAL INORGANIC NITRATE VIA BIOCONVERSION TO NITRITE . BASIC CLIN PHARMACOL vol. 105 , 31 - 31 .
Okorie M, Akram F, Loukogeorgakis S, Webb A, Deanfield J, Benjamin N, Hobbs A, MacAllister R et al. ( 2009 ) . ORAL INORGANIC NITRATE PROTECTS AGAINST ENDOTHELIAL ISCHAEMIA-REPERFUSION INJURY IN HUMANS . BASIC CLIN PHARMACOL vol. 105 , 26 - 26 .
Ahluwalia A ( 2009 ) . Erthrocyte and endothelial nitrite in hypoxia: role for NOS and XOR . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 20 , S24 - S24 .
Kapil V, Okorie M, Akram F, Rehman F, Milsom A, Arghandawi S, Pearl V, Deanfield J et al. ( 2009 ) . Oral inorganic nitrate lowers blood pressure and protects against endothelial ischaemia-reperfusion injury in humans . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 20 , S37 - S37 .
Milsom A, Patel N, Storey A, Cuzzocrea S, Mazzon E, Webb A, Hobbs A, Thiemermann C et al. ( 2009 ) . Role for endothelial nitric oxide synthase in nitrite-induced protection against renal ischaemia-reperfusion injury in mice . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 20 , S39 - S40 .
Duchene J, Ahluwalia A ( 2009 ) . The kinin B(1) receptor and inflammation: new therapeutic target for cardiovascular disease . Curr Opin Pharmacol vol. 9 , ( 2 ) 125 - 131 .
Ahluwalia A, De Felipe C, O'Brien J, Hunt SP, Perretti M ( 2009 ) . Impaired IL‐1β‐induced neutrophil accumulation in tachykinin NK1 receptor knockout mice . British Journal of Pharmacology vol. 124 , ( 6 ) 1013 - 1015 .
Kakuyama M, Vallance P, Ahluwalia A ( 2009 ) . Endothelium‐dependent sensory NANC vasodilatation: involvement of ATP, CGRP and a possible NO store . British Journal of Pharmacology vol. 123 , ( 2 ) 310 - 316 .
Ahluwalia A, Giuliani S, Scotland R, Maggi CA ( 2009 ) . Ovalbumin‐induced neurogenic inflammation in the bladder of sensitized rats . British Journal of Pharmacology vol. 124 , ( 1 ) 190 - 196 .
Scotland R, Vallance P, Ahluwalia A ( 2009 ) . Endothelin alters the reactivity of vasa vasorum: mechanisms and implications for conduit vessel physiology and pathophysiology . British Journal of Pharmacology vol. 128 , ( 6 ) 1229 - 1234 .
Bogle RG, McLean PG, Ahluwalia A, Vallance P ( 2009 ) . Impaired vascular sensitivity to nitric oxide in the coronary microvasculature after endotoxaemia . British Journal of Pharmacology vol. 130 , ( 1 ) 118 - 124 .
McLean PG, Perretti M, Ahluwalia A ( 2009 ) . Inducible expression of the kinin B1 receptor in the endotoxemic heart: mechanisms of des‐Arg9bradykinin‐induced coronary vasodilation . British Journal of Pharmacology vol. 128 , ( 2 ) 275 - 282 .
Klein J, Gonzalez J, Duchene J, Esposito L, Pradere JP, Neau E, Delage C, Calise D et al. ( 2009 ) . Delayed blockade of the kinin B1 receptor reduces renal inflammation and fibrosis in obstructive nephropathy . FASEB J vol. 23 , ( 1 ) 134 - 142 .
Hobbs AJ, Gane P, Lumsden N, Nobles M, Rebstock A-S, Simone M, Villar I, Worthington R et al. ( 2009 ) . Design and development of novel non-peptide agonists at natriuretic peptide receptor-C . FASEB JOURNAL vol. 23 ,
Tolstanova G, Khomenko T, Deng X, Chen L, Tarnawski A, Ahluwalia A, Szabo S, Sandor Z ( 2008 ) . Neutralizing Anti-Vascular Endothelial Growth Factor (VEGF) Antibody Reduces Severity of Experimental Ulcerative Colitis in Rats: Direct Evidence for the Pathogenic Role of VEGF . Journal of Pharmacology and Experimental Therapeutics vol. 328 , ( 3 ) 749 - 757 .
Webb AJ, Milsom AB, Rathod KS, Chu WL, Qureshi S, Lovell MJ, Lecomte FMJ, Perrett D et al. ( 2008 ) . Mechanisms Underlying Erythrocyte and Endothelial Nitrite Reduction to Nitric Oxide in Hypoxia Role for Xanthine Oxidoreductase and Endothelial Nitric Oxide Synthase . CIRC RES vol. 103 , ( 9 ) 957 - U114 .
Vessillier S, Duchene J, Vojnovic I, Ahluwalia A, Bishop-Bailey D, Chernajovsky Y, Warner TD ( 2008 ) . Stabilisation of atherosclerotic plaques: The latent targeting cytokines strategy . HEART . vol. 94 ,
Chan MV, Hobbs AJ, Scotland RS, Ahluwalia A ( 2008 ) . Nitric oxide-induced relaxation in female resistance arteries is endothelium-dependent . BASIC CLIN PHARMACOL . vol. 102 , 38 - 38 .
Villar IC, Hobbs AJ, Ahluwalia A ( 2008 ) . Sex differences in vascular function: implication of endothelium-derived hyperpolarizing factor . J ENDOCRINOL vol. 197 , ( 3 ) 447 - 462 .
Aboud Z, Misra S, Warner T, Miall P, Benjamin N, Hobbs A, Webb A, Ahluwalia A ( 2008 ) . The enterosalivary bioconversion of nitrate to nitrite underlies the blood pressure (BP) lowering and anti-platelet effects of a dietary nitrate load . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 65 , 999 - 999 .
Jandhyala DM, Ahluwalia A, Obrig T, Thorpe CM ( 2008 ) . ZAK: a MAP3Kinase that transduces Shiga toxin‐ and ricin‐induced proinflammatory cytokine expression . Cellular Microbiology vol. 10 , ( 7 ) 1468 - 1477 .
Webb A, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P et al. ( 2008 ) . Acute blood pressure lowering and vasoprotective effects of dietary nitrate . The FASEB Journal vol. 22 , ( S1 ) 737.30 - 737737 .
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P et al. ( 2008 ) . Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite . Hypertension vol. 51 , ( 3 ) 784 - 790 .
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Aboud Z, Misra S, Rashid R, Miall P et al. ( 2008 ) . Acute blood pressure lowering, vasoprotective, and antiplatelet properties of dietary nitrate via bioconversion to nitrite . Hypertension vol. 51 , 784 - 790 .
Milsom AB, Hobbs AJ, Ahluwalia A ( 2008 ) . Endothelial nitric oxide synthase acts as a nitrite reductase in human endotheliall cells . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 19 , S51 - S52 .
Chan M, Villar I, Scotland R, Ahluwalia A ( 2008 ) . Endothelium-derived hyperpolarising factor (EDHF) underlies sex-differences in the pressure-induced myogenic response . FASEB JOURNAL . vol. 22 ,
Ahluwalia A ( 2008 ) . Mechanisms of nitrite reduction in the cardiovascular system . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 19 , S27 - S27 .
Duchene J, Francis S, Lecomte F, Stidwill R, Singer M, Cayla C, Bader M, Perretti M et al. ( 2008 ) . Opposing effects of the kinin B<sub>1</sub> and B<sub>2</sub> receptors in LPS-induced hypotension . FASEB JOURNAL . vol. 22 ,
Scotland RS, Roy B, Duchene J, Ahluwalia A ( 2008 ) . Selective regulation of chemokine CXCL6 by estrogen receptorβ (ERβ) . FASEB JOURNAL . vol. 22 ,
Duchene J, Lecomte F, Ahmed S, Cayla C, Pesquero J, Bader M, Perretti M, Ahluwalia A ( 2007 ) . A novel inflammatory pathway involved in leukocyte recruitment: role for the kinin B1 receptor and the chemokine CXCL5 . J Immunol vol. 179 , ( 7 ) 4849 - 4856 .
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Rashid R, Deanfield J, Benjamin N, MacAllister R et al. ( 2007 ) . Acute blood pressure (BP) lowering and vasoprotective effects of beetroot juice: relationship to nitrite derived from dietary nitrate . J HUM HYPERTENS . vol. 21 , 834 - 835 .
Sexton A, McDonald M, Cayla C, Thiemermann C, Ahluwalia A ( 2007 ) . 12-Lipoxygenase-derived eicosanoids protect against myocardial ischemia/reperfusion injury via activation of neuronal TRPV1 . FASEB J vol. 21 , ( 11 ) 2695 - 2703 .
Tarnawski A, Pai R, Deng X, Ahluwalia A, Khomenko T, Tanigawa T, Akahoshi T, Sandor Z et al. ( 2007 ) . Aging Gastropathy—Novel Mechanisms: Hypoxia, Up-regulation of Multifunctional Phosphatase PTEN, and Proapoptotic Factors . Gastroenterology vol. 133 , ( 6 ) 1938 - 1947.e1 .
Villar IC, Panayiotou CM, Sheraz A, Madhani M, Scotland RS, Nobles M, Kemp-Harper B, Ahluwalia A et al. ( 2007 ) . Definitive role for natriuretic peptide receptor-C in mediating the vasorelaxant activity of C-type natriuretic peptide and endothelium-derived hyperpolarising factor . CARDIOVASC RES vol. 74 , ( 3 ) 515 - 525 .
Tripatara P, Patel NSA, Webb A, Rathod K, Lecomte FMJ, Mazzon E, Cuzzocrea S, Yaqoob MM et al. ( 2007 ) . Nitrite-derived nitric oxide protects the rat kidney against ischemia/reperfusion injury in vivo: role for xanthine oxidoreductase . J Am Soc Nephrol vol. 18 , ( 2 ) 570 - 580 .
Webb AJ, Patel N, Loukogeorgakis S, Okorie M, Rashid R, Deanfield J, Benjamin N, Macallister R et al. ( 2007 ) . Acute blood pressure lowering and vasoprotective effects of beetroot juice: relationship to nitrite derived from dietary nitrate . EUROPEAN HEART JOURNAL . vol. 28 , 865 - 866 .
Rathod KS, Webb AJ, Lovell MJ, Lecomte F, Ahluwalia A ( 2006 ) . Nitrite is reduced to nitric oxide by xanthine oxidoreductase and nitric oxide synthase in the erythrocyte membrane in hypoxemia . BLOOD . vol. 108 , 448A - 448A .
Villar IC, Ahluwalia A, Hobbs AJ ( 2006 ) . Distinct pathways regulate endothelium derived hyperpolarising factor-mediated responses in rat mesenteric arteries . ACTA PHARMACOL SIN vol. 27 , ( 9 ) 1276 - 1276 .
Villar IC, Francis S, Webb A, Hobbs AJ, Ahluwalia A ( 2006 ) . Novel aspects of endothelium-dependent regulation of vascular tone . KIDNEY INT vol. 70 , ( 5 ) 840 - 853 .
Halpern SM, Ahluwalia A, Makunura CN, Jordan S ( 2006 ) . Investigation of notalgia paraesthetica using laser Doppler velocimetry and immunohistochemistry before and after treatment with topical capsaicin . Journal of the European Academy of Dermatology and Venereology vol. 7 , ( 3 ) 228 - 234 .
Scotland RS, Duchene J, Hobbs A, Ahluwalia A ( 2006 ) . Gender-differences in leukocyte activation in vivo: role of endothelium-derived mediators . FASEB JOURNAL . vol. 20 , A1193 - A1193 .
Goddard A, McDonald M, Thiemermann C, Ahluwalia A ( 2006 ) . Identification of an endogenous cardioprotective pathway involving 12-lipoxygenase (12-LOX), C-fibers and the non-selective cation channel TRPV1 . FASEB JOURNAL . vol. 20 , A230 - A230 .
Duchene J, Lecomte F, Perretti M, Ahluwalia A ( 2006 ) . Inflammatory chemokine CXCL5 expression by endothelial cells is dependent upon kinin B1 receptor activation . FASEB JOURNAL . vol. 20 , A702 - A702 .
Scotland RS, Cohen M, Foster P, Lovell M, Mathur A, Ahluwalia A, Hobbs AJ ( 2005 ) . C-type natriuretic peptide inhibits leukocyte recruitment and platelet-leukocyte interactions via suppression of P-selectin expression . P NATL ACAD SCI USA vol. 102 , ( 40 ) 14452 - 14457 .
Webb A, Qureshi S, Benjamin N, Perrett D, Ahluwalia A ( 2005 ) . Xanthine oxidase activity provides an alternative source of no during ischaemia from inorganic nitrite in rat blood vessels . BRIT J CLIN PHARMACO vol. 59 , ( 5 ) 631 - 632 .
Duchene J, Perretti M, Ahluwalia A ( 2005 ) . Chemokine involvement in kinin B1 receptor-mediated leukocyte recruitment . FASEB JOURNAL . vol. 19 , A1512 - A1513 .
Ahluwalia A, Villar I, Scotland RS, Hobbs A ( 2005 ) . The natriuretic peptide receptor-C antagonist, M372049, blocks C-type natriuretic peptide and endothelium-derived hyperpolarizing factor-induced relaxation of resistance arteries . FASEB JOURNAL . vol. 19 , A1556 - A1556 .
Ahluwalia A, Hobbs AJ ( 2005 ) . Endothelium-derived C-type natriuretic peptide: more than just a hyperpolarizing factor . Trends Pharmacol Sci vol. 26 , ( 3 ) 162 - 167 .
McLean PG, Perretti M, Ahluwalia A ( 2005 ) . Kinin B1 receptors as novel anti-inflammatory targets . Expert Opinion on Therapeutic Targets vol. 4 , ( 2 ) 127 - 141 .
Vo PA, Lad B, Tomlinson JAP, Francis S, Ahluwalia A ( 2005 ) . autoregulatory role of endothelium-derived nitric oxide (NO) on Lipopolysaccharide-induced vascular inducible NO synthase expression and function . J Biol Chem vol. 280 , ( 8 ) 7236 - 7243 .
Scotland RS, Madhani M, Chauhan S, Moncada S, Andresen J, Nilsson H, Hobbs AJ, Ahluwalia A ( 2005 ) . Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice - Key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo . CIRCULATION vol. 111 , ( 6 ) 796 - 803 .
Scotland RS, Ahluwalia A, Hobbs AJ ( 2005 ) . C-type natniuretic peptide in vascular physiology and disease . PHARMACOL THERAPEUT vol. 105 , ( 2 ) 85 - 93 .
Ahluwalia A, SCOTLAND RS, Andersen J, Chauhan S, Moncada S, Nilsson H, Hobbs AJ, Madhani M ( 2005 ) . Investigation of Vascular Responses in Endothelial Nitric Oxide Synthase/Cyclooxygenase-1 Double-Knockout Mice: Key Role for Endothelium-Derived Hyperpolarizing Factor in the Regulation of Blood Pressure in Vivo . Circulation vol. 111 , ( 6 ) 796 - 803 .
AHLUWALIA A, Mathur A, Lovell M, Hobbs AJ, Cohen M, Scotland RS ( 2005 ) . C-type natriuretic peptide inhibits leukocyte recruitment and platelet aggregation . PNAS vol. 102 , ( 40 ) 14452 - 14457 .
AHLUWALIA A, Scotland RS, Hobbs AJ, Moncada S, Chauhan S, Andresen J, Nilsson H, Madhani M ( 2005 ) . Investigation of vascular responses in endothelial nitric oxide synthase/cyclooxygenase-1 double-knockout mice: key role for endothelium-derived hyperpolarizing factor in the regulation of blood pressure in vivo . Circulation vol. 111 , ( 6 ) 796 - 803 .
AHLUWALIA A, Francis S, Tomlinson JA, Lad B, Vo PA ( 2005 ) . role of endothelium-derived nitric oxide (NO) on Lipopolysaccharide-induced vascular inducible NO synthase expression and function . J Biol Chem vol. 25280 , ( 8 ) 7236 - 7243 .
Scotland RS, Chauhan S, Davis C, De Felipe C, Hunt S, Kabir J, Kotsonis P, Oh U et al. ( 2004 ) . Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction . Circ Res vol. 95 , ( 10 ) 1027 - 1034 .
AHLUWALIA A, Oh U, Kabir J, De Felipe C, Chauhan S, Scotland RS, Davis C, Hunt S et al. ( 2004 ) . Vanilloid receptor TRPV1, sensory C-fibers, and vascular autoregulation: a novel mechanism involved in myogenic constriction . Circ Res vol. 95 , ( 10 ) 1027 - 1034 .
Scotland R, Foster P, Ahluwalia A, Hobbs AJ ( 2004 ) . C-type natriuretic peptide inhibits leukocyte recruitment in vivo via natriuretic peptide receptor-C activation . CIRCULATION . vol. 110 , 240 - 240 .
Ahluwalia A, Foster P, Prescott C, Hobbs AJ ( 2004 ) . Endothelial C-type natriuretic peptide regulates coronary blood flow and prevents ischemia-reperfusion injury . CIRCULATION . vol. 110 , 77 - 77 .
Chauhan SD, Hobbs AJ, Ahluwalia A ( 2004 ) . C-type natriuretic peptide: new candidate for endothelium-derived hyperpolarising factor . INT J BIOCHEM CELL B vol. 36 , ( 10 ) 1878 - 1881 .
Webb A, Bond R, McLean P, Uppal R, Benjamin N, Ahluwalia A ( 2004 ) . Reduction of nitrite to nitric oxide during ischemia protects against myocardial ischemia-reperfusion damage . P NATL ACAD SCI USA vol. 101 , ( 37 ) 13683 - 13688 .
Hobbs A, Foster P, Prescott C, Scotland R, Ahluwalia A ( 2004 ) . Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury - Novel cardioprotective role for endothelium-derived C-type natriuretic peptide . CIRCULATION vol. 110 , ( 10 ) 1231 - 1235 .
Webb AJ, Bond R, Uppal R, Benjamin N, Ahluwalia A ( 2004 ) . Human and rat myocardium reduces nitrite to nitric oxide under ischaemic conditions, in a process dependent on xanthine oxidoreductase . JOURNAL OF HYPERTENSION . vol. 22 , S18 - S19 .
Foster P, Mathur A, Ahluwalia A ( 2004 ) . Bradykinin protects against ischemia/reperfusion injury by opening mitochondrial KATP channels in the endothelial cell: a role for nitric oxide . FASEB JOURNAL . vol. 18 , A230 - A230 .
AHLUWALIA A ( 2004 ) . DICHOTOMOUS ROLE OF THE ENDOTHELIUM IN LPS-INDUCED ENDOTHELIAL DYSFUNCTION . Shock vol. 21 , ( Supplement )
Ahluwalia A, MacAllister RJ, Hobbs AJ ( 2004 ) . Vascular actions of natriuretic peptides - Cyclic GMP-dependent and -independent mechanisms . BASIC RES CARDIOL vol. 99 , ( 2 ) 83 - 89 .
Ahluwalia A, Foster P, Scotland RS, McLean PG, Mathur A, Perretti M, Moncada S, Hobbs AJ ( 2004 ) . Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment . Proc Natl Acad Sci U S A vol. 101 , ( 5 ) 1386 - 1391 .
Phuong AV, Ladd B, Tomlinson JAP, Ahluwalia A ( 2004 ) . Essential role for endothelium-derived NO in lipopolysaccharide-induced iNOS expression and function . SHOCK . vol. 21 , 96 - 96 .
Ahluwalia A, PERRETTI M, Mathur A, Moncada S, McLean PG, Hobbs AJ, Scotland RS, Foster P ( 2004 ) . Inhibition of leukocyte-endothelial cell interactions by nitric oxide via a cGMP-mediated down-regulation of P-selectin expression . Proceedings of the National Academy of Sciences USA vol. 101 , 1386 - 1391 .
AHLUWALIA A, Hobbs A, Prescott C, Scotland R, Foster P ( 2004 ) . Natriuretic peptide receptor-C regulates coronary blood flow and prevents myocardial ischemia/reperfusion injury: novel cardioprotective role for endothelium-derived C-type natriuretic peptide . Circulation vol. 110 , ( 10 ) 1231 - 1235 .
AHLUWALIA A, Sarkar D, Aston D, McLean P ( 2004 ) . Protease-activated receptor (PAR)-2 causes endothelium-dependant, NO-independant coronary vasodilatation: involvement of C-fibres and EDHF . Circ. Res vol. 90 , 465 - 472 .
Ahluwalia A ( 2003 ) . To b'EET or not to b'EET? That is the question! . Clin Sci (Lond) vol. 105 , ( 4 ) 399 - 401 .
Webb A, McLean P, Ahluwalia A, Benjamin N ( 2003 ) . Inorganic nitrite: Protector against ischaemia reperfusion injury in the heart? . BRITISH JOURNAL OF PHARMACOLOGY . vol. 138 , U10 - U10 .
Chauhan SD, Seggara G, Vo PA, Macallister RJ, Hobbs AJ, Ahluwalia A ( 2003 ) . Protection against lipopolysaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice . FASEB J vol. 17 , ( 6 ) 773 - 775 .
Vo PA, Tomlinson JAP, Chauhan SD, Ahluwalia A ( 2003 ) . The role of the endothelium and constitutive NO in LPS-induced vasorelaxation . BRITISH JOURNAL OF PHARMACOLOGY . vol. 138 , U78 - U78 .
Foster P, Mathur A, McLean P, Perretti M, Moncada S, Ahluwalia A, Hobbs A ( 2003 ) . Anti-leukocyte properties of a novel non NO-based soluble guanylate cyclase activator, BAY 41-2272 . FASEB JOURNAL . vol. 17 , A1052 - A1052 .
Vo PA, Syed I, McLean P, Bascands JL, Perretti M, Ahluwalia A ( 2003 ) . Regulation of kinin B1 receptors in emlothelial cells by laminar shear stress . FASEB JOURNAL . vol. 17 , A1056 - A1056 .
Scotland RS, Chauhan SD, Hobbs AJ, Ahluwalia A ( 2003 ) . Characterisation of eNOS/COX-1 double knockout mice: a novel model for the study of endothelium-derived hyperpolarising factor . FASEB JOURNAL . vol. 17 , A225 - A225 .
Hobbs AJ, Chauhan SD, Nilsson H, Ahluwalia A ( 2003 ) . Endothelium-derived hyperpolarising factor (EDHF) is C-type natriuretic peptide (CNP) in mesenteric resistance arteries . FASEB JOURNAL . vol. 17 , A226 - A226 .
Chauhan SD, Nilsson H, Ahluwalia A, Hobbs AJ ( 2003 ) . Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor . P NATL ACAD SCI USA vol. 100 , ( 3 ) 1426 - 1431 .
Chauhan S, Rahman A, Nilsson H, Clapp L, MacAllister R, Ahluwalia A ( 2003 ) . NO contributes to EDHF-like responses in rat small arteries: a role for NO stores . Cardiovasc Res vol. 57 , ( 1 ) 207 - 216 .
Chauhan SD, MacAllister RJ, Hobbs AJ, Ahluwalia A ( 2002 ) . Mechanisms underlying the vasorelaxant activity of C-type natriuretic peptide (CNP) in rat mesenteric resistance arteries . FASEB J vol. 16 , ( 4 ) A572 - A572 .
McLean P, Ahluwalia A ( 2002 ) . Protease-activated receptor (PAR)-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia-reperfusion injury, involvement of lipoxygenase products, VR1 receptors and C-fibers . FASEB J vol. 16 , ( 4 ) A569 - A569 .
McLean PG, Aston D, Sarkar D, Ahluwalia A ( 2002 ) . Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation - Selective preservation in ischemia/reperfusion injury: Involvement of lipoxygenase products, VR1 receptors, and C-fibers . CIRC RES vol. 90 , ( 4 ) 465 - 472 .
Hesslinger C, Chen Z, Ahluwalia A, Selwood DL, Vallance P, Pfeilschifter J, Hingorani AD ( 2002 ) . Regulation of GTP Cyclohydrolase I by Estrogen . Chemistry and Biology of Pteridines and Folates , Springer Nature
Scotland RS, Chauhan S, Vallance PJ, Ahluwalia A ( 2001 ) . An endothelium-derived hyperpolarizing factor-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of endothelial nitric oxide synthase-derived nitric oxide . Hypertension vol. 38 , ( 4 ) 833 - 839 .
Ahluwalia A ( 2001 ) . Nepadutant Menarini Richerche . Curr Opin Investig Drugs vol. 2 , ( 7 ) 919 - 922 .
Ahluwalia A, SCOTLAND RS, Vallance PJ, Chauhan S ( 2001 ) . An EDHF-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of eNOS-derived nitric oxide . Hypertension vol. 38 , ( 4 ) 833 - 839 .
McLean PG, Perretti M, Ahluwalia A ( 2000 ) . Kinin B1 receptors and the cardiovascular system: regulation of expression and function . Cardiovascular Research vol. 48 , ( 2 ) 194 - 210 .
McLean PG, Ahluwalia A, Perretti M ( 2000 ) . Association between Kinin B1 Receptor Expression and Leukocyte Trafficking across Mouse Mesenteric Postcapillary Venules . Journal of Experimental Medicine vol. 192 , ( 3 ) 367 - 380 .
Scotland RS, Vallance PJT, Ahluwalia A ( 2000 ) . Endogenous factors involved in regulation of tone of arterial vasa vasorum: implications for conduit vessel physiology . Cardiovascular Research vol. 46 , ( 3 ) 403 - 411 .
Ahluwalia A, Scotland R ( 2000 ) . Activation of sensory C-fibres partially mediates the vascular myogenic response . FASEB JOURNAL vol. 14 , ( 4 ) A143 - A143 .
Chauhan SD, MacAllister RJ, Clapp LH, Ahluwalia A ( 2000 ) . Evidence that no may contribute to "EDHF-like" responses in rat mesenteric and hepatic small arteries . BRITISH JOURNAL OF PHARMACOLOGY vol. 129 ,
KAKUYAMA M, AHLUWALIA A, RODRIGO J, VALLANCE P ( 1999 ) . Cholinergic Contraction Is Altered in nNOS Knockouts . American Journal of Respiratory and Critical Care Medicine vol. 160 , ( 6 ) 2072 - 2078 .
Ahluwalia A, Perretti M ( 1999 ) . B1 receptors as a new inflammatory target. Could this B the 1? . Trends in Pharmacological Sciences vol. 20 , ( 3 ) 100 - 104 .
Varsani M, MacAllister R, Ahluwalia A, Marshall I ( 1999 ) . Investigation of the α<sub>1</sub> adrenoceptor subtype(s) mediating contraction in the human internal mammary artery . BRITISH JOURNAL OF PHARMACOLOGY vol. 127 ,
Scotland R, Vallance P, Ahluwalia A ( 1999 ) . On the regulation of tone in vasa vasorum . Cardiovascular Research vol. 41 , ( 1 ) 237 - 245 .
McLean PG, Perretti M, Ahluwalia A ( 1999 ) . The involvement of kinin B1 receptors in the hypotensive response to endotoxin in rats . BRITISH JOURNAL OF PHARMACOLOGY vol. 127 , U62 - U62 .
McLean PG, Perretti M, Ahluwalia A ( 1998 ) . Investigation of endotoxin-inducible B<sub>1</sub> and constitutive B<sub>2</sub> kinin receptors mediating coronary vasodilation in the rat isolated heart . NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY vol. 358 , ( 1 ) R335 - R335 .
Ahluwalia A ( 1998 ) . Topical glucocorticoids and the skin‐mechanisms of action: an update . Mediators of Inflammation vol. 7 , ( 3 ) 183 - 193 .
Ahluwalia A, Bhagat K ( 1997 ) . An insight into recent developmens in understanding the mechanisms and management of septic shock . International Journal of Pharmaceutical Medicine . vol. 11 , 281 - 285 .
Ahluwalia A, Vallance P ( 1997 ) . Evidence for functional responses to sensory nerve stimulation of rat small mesenteric veins . Journal of Pharmacology and Experimental Therapeutics vol. 281 , ( 1 ) 9 - 14 .
Ahluwalia A, Giuliani S, Maggi CA ( 1997 ) . Allergic inflammation in the rat urinary bladder: Involvement of mast cells and C-fibres . BRITISH JOURNAL OF PHARMACOLOGY vol. 122 ,
Scotland RS, Vallance PJ, Ahluwalia A ( 1997 ) . Comparison of vascular reactivity of porcine aorta and its vasa vasorum . CIRCULATION vol. 96 , ( 8 ) 908 - 908 .
Kakuyama M, Vallance PJ, Ahluwalia A ( 1997 ) . P-30 Non-adrenergic non-cholinergic relaxation of the rabbit mesenteric small artery: Involvement of NO . Journal of Pharmacological Sciences vol. 75 ,
Ahluwalia A, Cellek S ( 1997 ) . Regulation of the cardiovascular system by non-adrenergic non-chollnergic nerves . Current Opinion in Nephrology & Hypertension vol. 6 , ( 1 ) 74 - 79 .
Ahluwalia A, Vallance P ( 1996 ) . Interaction between sympathetic and sensory nerves in rat small arteries: involvement of nitric oxide . American Journal of Physiology vol. 271 , ( 3 ) h969 - h976 .
Ahluwalia A, Perretti M ( 1996 ) . Involvement of bradykinin B1 receptors in the polymorphonuclear leukocyte accumulation induced by IL-1 beta in vivo in the mouse . The Journal of Immunology vol. 156 , ( 1 ) 269 - 274 .
Ahluwalia A, Vallance PJ ( 1996 ) . Reactivity of the vasa vasorum . CIRCULATION vol. 94 , ( 8 ) 3443 - 3443 .
Ahluwalia A, Newbold P, Brain SD, Flower RJ ( 1995 ) . Topical glucocorticoids inhibit neurogenic inflammation: involvement of lipocortin 1 . European Journal of Pharmacology vol. 283 , ( 1-3 ) 193 - 198 .
AHLUWALIA A, GIULIANI S, MAGGI CA ( 1995 ) . DEMONSTRATION OF A SEPTIDE-SENSITIVE INFLAMMATORY RESPONSE IN RAT SKIN . BRITISH JOURNAL OF PHARMACOLOGY vol. 114 , P41 - P41 .
AHLUWALIA A, NEWBOLD P, FLOWER RJ ( 1995 ) . TOPICAL GLUCOCORTICOIDS INHIBIT NEUROGENIC INFLAMMATION - INVOLVEMENT OF LIPOCORTIN-1 . BRITISH JOURNAL OF PHARMACOLOGY vol. 114 , P61 - P61 .
Ahluwalia A, Perretti M ( 1994 ) . Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse . European Journal of Pharmacology vol. 264 , ( 3 ) 407 - 415 .
Ahluwalia A, Mohamed RW, Flower RJ ( 1994 ) . Induction of lipocortin 1 by topical steroid in rat skin . Biochemical Pharmacology vol. 48 , ( 8 ) 1647 - 1654 .
Ahluwalia A, Perretti M ( 1994 ) . Anti-inflammatory effect of prostanoids in mouse and rat skin: evidence for a role of EP3-receptors . Journal of Pharmacology and Experimental Therapeutics vol. 268 , ( 3 ) 1526 - 1531 .
AHLUWALIA A, FLOWER RJ ( 1994 ) . CHARACTERIZATION OF CAPSAICIN-INDUCED VASODILATION OF THE PERFUSED RABBIT EAR AND ITS MODULATION BY DEXAMETHASONE . BRITISH JOURNAL OF PHARMACOLOGY vol. 112 , U104 - U104 .
Perretti M, Ahluwalia A, Harris JG, Goulding NJ, Flower RJ ( 1993 ) . Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody . The Journal of Immunology vol. 151 , ( 8 ) 4306 - 4314 .
Perretti M, Ahluwalia A, Flower RJ, Manzini S ( 1993 ) . Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: involvement of NK-1 receptors . Immunology vol. 80 , ( 1 ) 73 - 77 .
Ahluwalia A, Flower RJ ( 1993 ) . Effect of chronic capsaicin and guanethidine treatment on skin blood flow of the rat . Inflammation Research . vol. 38 , c16 - c18 .
AHLUWALIA A, FLOWER RJ, PERRETTI M ( 1993 ) . DUAL-ACTION OF PROSTAGLANDINS (PGS) IN THE MOUSE SKIN EDEMA TEST . BRITISH JOURNAL OF PHARMACOLOGY vol. 109 , P5 - P5 .
AHLUWALIA A, FLOWER RJ ( 1993 ) . Topical betamethasone‐17‐valerate inhibits heat‐induced vasodilatation in man . British Journal of Dermatology vol. 128 , ( 1 ) 45 - 48 .
AHLUWALIA A, FLOWER RJ ( 1992 ) . TOPICAL STEROIDS AND ACE INHIBITORS - A COMMON LINK . BRITISH JOURNAL OF PHARMACOLOGY vol. 106 , P5 - P5 .