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Research

Publications: Prof Amrita Ahluwalia

Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP et al. ( 2022 ) . Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide . British Journal of Pharmacology vol. 179 , ( 20 ) 4757 - 4777 .
Hikin L, Ahluwalia A, Morley S, Smith P ( 2022 ) . Sodium nitrite poisoning; A case series of 15 fatalities . Toxicologie Analytique et Clinique vol. 34 , ( 3 ) s48 - s49 .
Curtis MJ, Alexander SPH, Cirino G, George CH, Kendall DA, Insel PA, Izzo AA, Ji Y et al. ( 2022 ) . Planning experiments: Updated guidance on experimental design and analysis and their reporting III . British Journal of Pharmacology vol. 179 , ( 15 ) 3907 - 3913 .
Shabbir A, Rathod K, Primus C, Lau C, Chhetri I, Ono M, Khambata R, Massimo G et al. ( 2022 ) . BS37 Leukocytic nitrate reductase activity mitigates systemic inflammation-induced endothelial dysfunction in humans by accelerating resolution . Conference: Basic sciencea167.1 - a1a167 .
Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Montalvo Moreira SA, Rathod K, Chen J et al. ( 2022 ) . 20-hydroxyeicosatetraenoic acid (20-HETE) is a pivotal endogenous ligand for TRPV1-mediated neurogenic inflammation in the skin . British Journal of Pharmacology vol. 179 , ( 7 ) 1450 - 1469 .
Spitschan M, Santhi N, Ahluwalia A, Fischer D, Hunt L, Karp NA, Lévi F, Pinedatorra I et al. ( 2022 ) . Science Forum: Sex differences and sex bias in human circadian and sleep physiology research . eLife vol. 11 ,
Maffia P, Antoniades C, Ahluwalia A, Cirino G ( 2021 ) . Molecular imaging—The first visual themed issue published in the British Journal of Pharmacology . British Journal of Pharmacology vol. 178 , ( 21 ) 4213 - 4215 .
Wang J, Mei F, Bai L, Zhou S, Liu D, Yao L, Ahluwalia A, Ghiladi RA et al. ( 2021 ) . Serum nitrite and nitrate: A potential biomarker for post-covid-19 complications? . Free Radical Biology and Medicine vol. 175 , 216 - 225 .
Primus C, Masucci M, Whitear C, Moreira SAM, Kumar NA, Chhetri I, Rathod KS, Khambata R et al. ( 2021 ) . A pro-resolving phenotype underpins the anti-inflammatory effects of inorganic nitrate . European Heart Journal vol. 42 , ( Supplement_1 )
Lau C, Shabbir A, Rathod KS, Chhetri I, Ono M, Hamers AJP, Amarin JJ, Ibrahim A et al. ( 2021 ) . Inorganic nitrate attenuates endothelial dysfunction consequent to systemic inflammation . European Heart Journal vol. 42 , ( Supplement_1 )
Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V et al. ( 2021 ) . Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers . European Heart Journal vol. 42 , ( Supplement_1 )
Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V et al. ( 2021 ) . Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers . EUROPEAN HEART JOURNAL . vol. 42 , 3009 - 3009 .
George CH, Alexander SPH, Cirino G, Insel PA, Izzo AA, Ji Y, Kendall DA, Panettieri RA et al. ( 2021 ) . Editorial policy regarding the citation of preprints in the British Journal of Pharmacology (BJP) . British Journal of Pharmacology vol. 178 , ( 18 ) 3605 - 3610 .
Beirne A-M, Rathod KS, Castle E, Andiapen M, Richards A, Bellin A, Hammond V, Godec T et al. ( 2021 ) . The BYPASS-CTCA Study: the value of Computed Tomography Cardiac Angiography (CTCA) in improving patient-related outcomes in patients with previous bypass operation undergoing invasive coronary angiography: Study Protocol of a Randomised Controlled Trial . Ann Transl Med vol. 9 , ( 17 )
Beirne AM, Mitchelmore O, Palma S, Andiapen M, Rathod KS, Hammond V, Bellin A, Cooper J et al. ( 2021 ) . NITRATE-CIN Study: Protocol of a Randomized (1:1) Single-Center, UK, Double-Blind Placebo-Controlled Trial Testing the Effect of Inorganic Nitrate on Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography for Acute Coronary Syndromes . Journal of Cardiovascular Pharmacology and Therapeutics vol. 26 , ( 4 ) 303 - 309 .
Shabbir A, Ahluwalia A ( 2021 ) . Second wave and second opportunity: capitalizing on cardiovascular research activity during the COVID-19 pandemic . European heart journal. Quality of care & clinical outcomes vol. 7 , ( 3 ) 321 - 322 .
Kelham M, Choudry FA, Hamshere S, Beirne AM, Rathod KS, Baumbach A, Ahluwalia A, Mathur A et al. ( 2021 ) . Therapeutic Implications of COVID-19 for the Interventional Cardiologist . Journal of Cardiovascular Pharmacology and Therapeutics vol. 26 , ( 3 ) 203 - 216 .
Shabbir A, Rathod KS, Khambata RS, Ahluwalia A ( 2021 ) . Sex Differences in the Inflammatory Response: Pharmacological Opportunities for Therapeutics for Coronary Artery Disease . Annual Review of Pharmacology and Toxicology vol. 61 , 333 - 359 .
Rathod KS, Jones DA, Jain AK, Lim P, MacCarthy PA, Rakhit R, Lockie T, Kalra S et al. ( 2021 ) . The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction . Am J Cardiovasc Dis vol. 11 , ( 5 ) 659 - 678 .
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research . Experimental Physiology vol. 105 , ( 9 ) 1459 - 1466 .
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research* . Journal of Cerebral Blood Flow and Metabolism vol. 40 , ( 9 ) 1769 - 1777 .
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The ARRIVE guidelines 2.0: updated guidelines for reporting animal research . Journal of Physiology vol. 598 , ( 18 ) 3793 - 3801 .
Lilley E, Stanford SC, Kendall DE, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA et al. ( 2020 ) . ARRIVE 2.0 and the British Journal of Pharmacology: Updated guidance for 2020 . British Journal of Pharmacology vol. 177 , ( 16 ) 3611 - 3616 .
Cirino G, Ahluwalia A ( 2020 ) . The many mechanisms of action of Chloroquine: to use or not to use (in COVID-19) that is the question . British Journal of Pharmacology vol. 177 , ( 15 ) 3361 - 3362 .
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research . British Journal of Pharmacology
du Sert NP, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A, Cuthill IC et al. ( 2020 ) . Reporting animal research: Explanation and elaboration for the arrive guidelines 2.0 . PLoS Biology vol. 18 , ( 7 )
Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM, Ahluwalia A ( 2020 ) . The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway . Pharmacological reviews vol. 72 , ( 3 ) 692 - 766 .
du Sert NP, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The arrive guidelines 2.0: Updated guidelines for reporting animal research . PLoS Biology vol. 18 , ( 7 )
Izzo AA, Teixeira M, Alexander SPH, Cirino G, Docherty JR, George CH, Insel PA, Ji Y et al. ( 2020 ) . A practical guide for transparent reporting of research on natural products in the British Journal of Pharmacology: Reproducibility of natural product research . British Journal of Pharmacology vol. 177 , ( 10 ) 2169 - 2178 .
Percie Du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Browne WJ, Clark A et al. ( 2020 ) . The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research . BMJ Open Science vol. 4 , ( 1 )
Lau CWZ, Hamers AJP, Rathod KS, Shabbir A, Cooper J, Primus CP, Davies C, Mathur A et al. ( 2020 ) . Randomised, double-blind, placebo-controlled clinical trial investigating the effects of inorganic nitrate in hypertension-induced target organ damage: Protocol of the NITRATE-TOD study in the UK . BMJ Open vol. 10 , ( 1 )
Dreyer G, Kieswich J, Harwood S, Ahluwalia A, Yaqoob MM ( 2019 ) . Ergocalciferol improves endothelial vasodilatory and vasoconstrictor function in an in vivo model of mild uraemia . Bioscience Reports vol. 39 , ( 12 )
( 2019 ) . Natural Mutations of the Human Xdh Impact upon the Nitric Oxide-generating Capacity of Xanthine Oxidoreductase . Free Radical Biology and Medicine . vol. 145 ,
George CH, Alexander SPH, Cirino G, Docherty JR, Hoyer D, Insel PA, Izzo AA, Ji Y et al. ( 2019 ) . The BJP expects authors to share data . British Journal of Pharmacology vol. 176 , ( 24 ) 4595 - 4598 .
Ingram JR, Ahluwalia A ( 2019 ) . The pharmacology of itch . British Journal of Pharmacology vol. 176 , ( 23 ) 4419 - 4420 .
Docherty JR, Stanford SC, Panattieri RA, Alexander SPH, Cirino G, George CH, Hoyer D, Izzo AA et al. ( 2019 ) . Sex: A change in our guidelines to authors to ensure that this is no longer an ignored experimental variable . British Journal of Pharmacology vol. 176 , ( 21 ) 4081 - 4086 .
Ingram JR, Ahluwalia A ( 2019 ) . The pharmacology of itch . British Journal of Dermatology
Jones DA, Rathod KS, Williamson A, Mand K, Harrington D, Andiapen M, van Eijl S, Westwood M et al. ( 2019 ) . Corrigendum to “The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction” [Int. J. Cardiol. 266 (2018) 1–6](S0167527317358527)(10.1016/j.ijcard.2018.01.029) . International Journal of Cardiology vol. 292 ,
Jones DA, Mathur A, Ahluwalia A ( 2019 ) . Letter by Jones et al regarding article, “Optimized treatment of ST-elevation myocardial infarction” . Circulation Research vol. 125 , ( 6 ) E29 - E29 .
Percie du Sert N, Ahluwalia A, Alam S, Avey M, Baker M, Browne W, Clark A, Cuthill I et al. ( 2019 ) . Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019 .
Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey M, Baker M, Browne W, Clark A et al. ( 2019 ) . The ARRIVE guidelines 2019: updated guidelines for reporting animal research .
Guzik TJ, Ahluwalia A ( 2019 ) . Plan S: In Service or Disservice to Society? . European Heart Journal vol. 40 , ( 12 ) 949 - 952 .
Guzik TJ, Ahluwalia A ( 2019 ) . Plan S: In service or disservice to society? . British Journal of Pharmacology vol. 176 , ( 6 ) 753 - 756 .
Ahluwalia A ( 2018 ) . P2 Inorganic Nitrate as a Regulator of Vascular Function . Free Radical Biology and Medicine . vol. 128 ,
Percie Du Sert N, Hurst V, Ahluwalia A, Alam S, Altman DG, Avey MT, Baker M, Browne W et al. ( 2018 ) . Revision of the ARRIVE guidelines: Rationale and scope . BMJ Open Science vol. 2 , ( 1 )
Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, S. Watson D, Barnes MR et al. ( 2018 ) . Sex differences in the nitrate-nitrite-NO <sup>•</sup> pathway: Role of oral nitrate-reducing bacteria . Free Radical Biology and Medicine vol. 126 , 113 - 121 .
Curtis MJ, Ashton JC, Moon LDF, Ahluwalia A ( 2018 ) . Clarification of the basis for the selection of requirements for publication in the British Journal of Pharmacology . British Journal of Pharmacology vol. 175 , ( 18 ) 3633 - 3635 .
Jones DA, Rathod KS, Williamson A, Harrington D, Andiapen M, van Eijl S, Westwood M, Antoniou S et al. ( 2018 ) . The effect of intracoronary sodium nitrite on the burden of ventricular arrhythmias following primary percutaneous coronary intervention for acute myocardial infarction . International Journal of Cardiology vol. 266 , 1 - 6 .
AHLUWALIA A, JONES D, MATHUR A ( 2018 ) . Sodium Nitrite-Mediated Cardioprotection in Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: A Cost-Effectiveness Analysis . Journal of Cardiovascular Pharmacology and Therapeutics
Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A, Ahluwalia A ( 2018 ) . P2564Sodium nitrite-mediated cardioprotection in primary percutaneous coronary intervention for ST-elevation myocardial infarction: a cost-effectiveness analysis . European Heart Journal vol. 39 , ( suppl_1 )
Jones DA, Whittaker P, Rathod KS, Richards AJ, Andiapen M, Antoniou S, Mathur A, Ahluwalia A ( 2018 ) . Sodium nitrite-mediated cardioprotection in primary percutaneous coronary intervention for ST-elevation myocardial infarction: a cost-effectiveness analysis . EUROPEAN HEART JOURNAL . vol. 39 , 504 - 504 .
Ahluwalia A, Cirino G ( 2018 ) . Launch of mini-reviews in hot topics . British Journal of Pharmacology vol. 175 , ( 13 )
Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J et al. ( 2018 ) . Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis . FASEB Jfj201701303R - fj201701303R .
Yellon DM, He Z, Khambata R, Ahluwalia A, Davidson SM ( 2018 ) . The GTN patch: a simple and effective new approach to cardioprotection? . Basic Research in Cardiology vol. 113 , ( 3 )
Curtis MJ, Alexander S, Cirino G, Docherty JR, George CH, Giembycz MA, Hoyer D, Insel PA et al. ( 2018 ) . Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers . British Journal of Pharmacology vol. 175 , ( 7 ) 987 - 993 .
AHLUWALIA A ( 2018 ) . Goals and practicalities of immunoblotting and immunohistochemistry: A guide for submission to the British Journal of Pharmacology . British Journal of Pharmacology vol. 175 , 407 - 411 .
Osborne NJ, Ritskes-Hoitinga M, Ahluwahlia A, Alam S, Brown M, Henderson H, de Leeuw W, Marsh J et al. ( 2017 ) . Letter to the editor - round table unites to tackle culture change in an effort to improve animal research reporting . BMC Veterinary Research vol. 13 , ( 1 )
Kapil V ( 2017 ) . Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017 . BMC Pharmacol Toxicol vol. 18 , ( Suppl 1 ) 64 - 64 .
Campo G, Pavasini R, Morciano G, Lincoff AM, Gibson CM, Kitakaze M, Lonborg J, Ahluwalia A et al. ( 2017 ) . Clinical benefit of drugs targeting mitochondrial function as an adjunct to reperfusion in ST-segment elevation myocardial infarction: A meta-analysis of randomized clinical trials . International Journal of Cardiology vol. 244 , 59 - 66 .
Campo G, Pavasini R, Morciano G, Lincoff MA, C. Gibson M, Kitakaze M, Lonborg J, Ahluwalia A et al. ( 2017 ) . Data on administration of cyclosporine, nicorandil, metoprolol on reperfusion related outcomes in ST-segment Elevation Myocardial Infarction treated with percutaneous coronary intervention . Data in Brief vol. 14 , 197 - 205 .
Rathod KS, Hamshere S, Khambata RS, Andiapen M, Westwood M, Mathur A, Ahluwalia A, Jones DA ( 2017 ) . Combined analysis of the safety of intra-coronary drug delivery during primary percutaneous coronary intervention for acute myocardial infarction: A study of three clinical trials . JRSM Cardiovasc Dis vol. 6 , 2048004017725988 - 2048004017725988 .
Yuzugulen J, Douthwaite JA, Wood EG, Villar IC, Patel NSA, Jegard J, Gaertner H, Rossitto-Borlat I et al. ( 2017 ) . Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1 . Sci Rep vol. 7 , ( 1 ) 4956 - 4956 .
Hamers AJP, Ahluwalia A ( 2017 ) . Arachidonic acid metabolites induce TRPV1-mediated inflammation . FASEB JOURNAL . vol. 31 ,
Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al. ( 2017 ) . Sex differences in the inflammatory response and inflammation-induced vascular dysfunction . LANCET . Conference: FASEB vol. 389 , 20 - 20 .
AHLUWALIA A ( 2017 ) . The anti-inflammatory actions of inorganic nitrate stabilise the atherosclerotic plaque . Proceedings of the National Academy of Sciences of USA
Jones DA, Rathod KS, Ahluwalia A ( 2017 ) . Chapter 15 Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation . Nitric Oxide ,
Jones DA, Rathod KS, Ahluwalia A ( 2017 ) . Update on Nitrite Reduction in Ischemic Disease: Mechanisms and Clinical Translation . Nitric Oxide: Biology and Pathobiology: Third Edition ,
George CH, Stanford SC, Alexander S, Cirino G, Docherty JR, Giembycz MA, Hoyer D, Insel PA et al. ( 2017 ) . Updating the guidelines for data transparency in the British Journal of Pharmacology – data sharing and the use of scatter plots instead of bar charts . British Journal of Pharmacology vol. 174 , ( 17 ) 2801 - 2804 .
Rathod KS, Jones DA, Van-Eijl TJA, Tsang H, Warren H, Hamshere SM, Kapil V, Jain AK et al. ( 2016 ) . Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: Protocol of the NITRATE-OCT study . BMJ Open vol. 6 , ( 12 )
AHLUWALIA A ( 2016 ) . Accelerated resolution underlies sex differences in the inflammatory response in human . Journal of Clinical Investigation vol. 127 , ( 1 ) 169 - 182 .
Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A ( 2016 ) . ACTIVATION OF TRPV1 BY 12(S)-HPETE AND 20-HETE RELEASES CGRP AND PROTECTS THE HEART AGAINST THE CARDIAC DYSFUNCTION CAUSED BY LPS . SHOCK . Conference: Exp Biology 2016 vol. 46 , 31 - 32 .
Jones DA, Khambata RS, Andiapen M, Rathod KS, Mathur A, Ahluwalia A ( 2016 ) . Intracoronary nitrite suppresses the inflammatory response following primary percutaneous coronary intervention . Heart
Ahluwalia A, Gladwin M, Coleman GD, Hord N, Howard G, Kim-Shapiro DB, Lajous M, Larsen FJ et al. ( 2016 ) . Dietary Nitrate and the Epidemiology of Cardiovascular Disease: Report From a National Heart, Lung, and Blood Institute Workshop . Journal of the American Heart Association vol. 5 , ( 7 )
Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A ( 2016 ) . Activation of TRPV1 by 12(s)-HpETE and 20-HETE Releases CGRP and Protects the Heart Against the Cardiac Dysfunction Caused by LPS . FASEB JOURNAL . Conference: Exp Biology (FASEB) 2016 vol. 30 ,
Khambata RS, Ghosh SM, Rathod KS, Thevathasan T, Ahluwalia A ( 2016 ) . Dietary Nitrate Supresses Leukocyte Recruitment and Activation in Apolipoprotein E Knockout Mice . FASEB JOURNAL . vol. 30 ,
Filomena F, Khambata R, Ahluwalia A ( 2016 ) . Dietary nitrate suppresses platelet reactivity in Apolipoprotein E Knockout Mice . FASEB JOURNAL . vol. 30 ,
Rathod KS, Siddiqui U, Hartley A, Khambata RS, Ahluwalia A ( 2016 ) . Investigation of the influence of sex on cantharidin-induced inflammation in healthy volunteers . FASEB JOURNAL . vol. 30 ,
Lara J, Ashor AW, Oggioni C, Ahluwalia A, Mathers JC, Siervo M ( 2016 ) . Effects of inorganic nitrate and beetroot supplementation on endothelial function: a systematic review and meta-analysis . European Journal of Nutrition vol. 55 , ( 2 ) 451 - 459 .
Rathod KS, Velmurugan S, Ahluwalia A ( 2016 ) . A 'green' diet-based approach to cardiovascular health? Is inorganic nitrate the answer? . Molecular Nutrition and Food Research vol. 60 , ( 1 ) 185 - 202 .
Gee LC, Ahluwalia A ( 2016 ) . Dietary Nitrate Lowers Blood Pressure: Epidemiological, Pre-clinical Experimental and Clinical Trial Evidence . Current Hypertension Reports vol. 18 , ( 2 ) 1 - 14 .
Velmurugan S, Gan JM, Rathod KS, Khambata RS, Ghosh SM, Hartley A, Van Eijl S, Sagi-Kiss V et al. ( 2016 ) . Dietary nitrate improves vascular function in patients with hypercholesterolemia: A randomized, double-blind, placebo-controlled study . American Journal of Clinical Nutrition vol. 103 , ( 1 ) 25 - 38 .
Fernandes D, Khambata R, Ahluwalia A ( 2015 ) . Effects of Inorganic Nitrate on Endothelial Dysfunction Induced by Periodontitis . CIRCULATION . vol. 132 ,
Curtis MJ, Bond RA, Spina D, Ahluwalia A, Alexander SP, Giembycz MA ( 2015 ) . Erratum: Experimental design and analysis and their reporting: New guidance for publication in BJP (British Journal of Pharmacology (2015) 172 (3461-3471) 10.1111/bph.12856)) . British Journal of Pharmacology vol. 172 , ( 18 )
Khambata RS, Ghosh SM, Ahluwalia A ( 2015 ) . "Repurposing" of Xanthine Oxidoreductase as a Nitrite Reductase: A New Paradigm for Therapeutic Targeting in Hypertension . Antioxidants and Redox Signaling vol. 23 , ( 4 ) 340 - 353 .
Velmurugan S, Ghosh SM, Khambata RS, Van Eijl S, Robertson A, Chowdhury TA, Ahluwalia A ( 2015 ) . Acute administration of dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia . EUROPEAN HEART JOURNAL . vol. 36 , 257 - 257 .
Curtis MJ, Bond RA, Spina D, Ahluwalia A, Alexander SPA, Giembycz MA, Gilchrist A, Hoyer D et al. ( 2015 ) . Experimental design and analysis and their reporting: New guidance for publication in BJP . British Journal of Pharmacology vol. 172 , ( 14 ) 3461 - 3471 .
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2015 ) . Erratum: Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex (Free Radical Biology and Medicine (2013) 65 (1521-1532)) . Free Radical Biology and Medicine vol. 84 ,
Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A ( 2015 ) . Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study . Hypertension vol. 65 , ( 2 ) 320 - 327 .
Rathod KS, Velmurugan S, Ahluwalia A ( 2015 ) . A 'green' diet-based approach to cardiovascular health? Is inorganic nitrate the answer? . Molecular Nutrition and Food Research
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2015 ) . Erratum to "Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex" [Free Radic. Biol. Med. 65 (2013) 1521-1532] . Free Radical Biology and Medicine
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, Van Eijl S, Webb AJ et al. ( 2015 ) . Randomized phase 2 trial of intracoronary nitrite during acute myocardial infarction . Circulation Research vol. 116 , ( 3 ) 437 - 447 .
Jones DA, Pellaton C, Velmurugan S, Rathod KS, Andiapen M, Antoniou S, van Eijl S, Webb AJ et al. ( 2014 ) . Randomized Phase 2 Trial of Intra-Coronary Nitrite During Acute Myocardial Infarction . Circulation Research
Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A ( 2014 ) . Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients: A Randomized, Phase 2, Double-Blind, Placebo-Controlled Study . Hypertension
Velmurugan S, Ghosh S, Khambata R, Van Eijl S, Robertson A, Chowdhury T, Ahluwalia A ( 2014 ) . Dietary nitrate improves endothelial function and vascular stiffness in hypercholesterolemia . Nitric Oxide vol. 42C ,
Rathod K, Ghosh S, Khambata R, Ahluwalia A ( 2014 ) . Xanthine oxidoreductase in atherosclerotic mice: Determination of expression and nitrite reductase activity . Nitric Oxide vol. 42C ,
Jones DA, Pellaton C, Velmurugan S, Andiapen M, Antoniou S, Van Eijl S, Westwood MA, Webb AJ et al. ( 2014 ) . P141 The safety and efficacy of intra-coronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): A single centre, randomised, double-blind controlled trial . Nitric Oxide vol. 42 , 127 - 128 .
Velmurugan S, Ghosh SM, Khambata RS, Robertson AC, Van Eijl TJA, Chowdhury TA, Ahluwalia A ( 2014 ) . Dietary nitrate improves endothelial function, vascular stiffness and modifies platelet markers of atherogenesis in hypercholesterolemia . EUROPEAN HEART JOURNAL . vol. 35 , 1047 - 1047 .
Moyes AJ, Khambata RS, Villar I, Bubb KJ, Baliga RS, Lumsden NG, Xiao F, Gane PJ et al. ( 2014 ) . Endothelial C-type natriuretic peptide maintains vascular homeostasis . J Clin Invest vol. 124 , ( 9 ) 4039 - 4051 .
Jones DA, Pellaton C, Velmurugan S, Andiapen M, Antoniou S, Van Eijl S, Westwood M, Parmar MK et al. ( 2014 ) . The safety and efficacy of intracoronary nitrite infusion during acute myocardial infarction (NITRITE-AMI): a single centre, randomised, double-blind controlled trial . EUROPEAN HEART JOURNAL . vol. 35 , 1154 - 1155 .
Ghosh S, Khambata R, Ahluwalia A ( 2014 ) . DIETARY INORGANIC NITRATE REDUCES INFLAMMATORY CELL RECRUITMENT IN MICE . BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY . vol. 115 , 17 - 17 .
Kapil V, Weitzberg E, Lundberg JO, Ahluwalia A ( 2014 ) . Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health . Nitric Oxide - Biology and Chemistry vol. 38 , ( 1 ) 45 - 57 .
Kapil V, Weitzberg E, Lundberg JO, Ahluwalia A ( 2014 ) . Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health . Nitric Oxide vol. 38 , 45 - 57 .
Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2013 ) . Antiplatelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex . Free Radic Biol Med vol. 65 , 1521 - 1532 .
Yuzugulen J, Wood EG, Villar IC, Douthwaite JA, Patel NSAI, Jegard J, Montoya A, Cutillas P et al. ( 2013 ) . Characterisation of the “Endothelin-Like Domain Peptide” (ELDP) co-synthesised with Endothelin-1 from the EDN1 gene . Life Sciences vol. 93 , ( 25-26 )
Bubb KJ, Wen H, Panayiotou CM, Finsterbusch M, Khan FJ, Chan MV, Priestley JV, Baker MD et al. ( 2013 ) . Activation of neuronal transient receptor potential vanilloid 1 channel underlies 20-hydroxyeicosatetraenoic acid-induced vasoactivity: role for protein kinase A . Hypertension vol. 62 , ( 2 ) 426 - 433 .
Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S et al. ( 2013 ) . Enhanced vasodilator activity of nitrite in hypertension: critical role for erythrocytic xanthine oxidoreductase and translational potential . Hypertension vol. 61 , ( 5 ) 1091 - 1102 .
Ghosh SM, Kapil V, Bubb K, Fuentes-Calvo I, Ahluwalia A ( 2013 ) . Mechanisms underlying nitrite reduction in hypertension: Role for erythrocytic xanthine oxidoreductase . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 31 , S24 - S25 .
Jones DA, Khambata RS, Mathur A, Ahluwalia A ( 2013 ) . Sodium nitrite promotes the viability and proliferation of endothelial cells but inhibits the growth of smooth muscle cells under hypoxia . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 31 , S22 - S22 .
Martin K, Perretti M, Ahluwalia A ( 2013 ) . Kinin B1 receptor regulates inflammatory cell recruitment during low laminar shear stress . FASEB JOURNAL . vol. 27 ,
Rousselle A, Qadri F, Leukel L, Yilmaz R, Fontaine J-F, Sihn G, Bader M, Ahluwalia A et al. ( 2013 ) . CXCL5 limits macrophage foam cell formation in atherosclerosis . JOURNAL OF CLINICAL INVESTIGATION vol. 123 , ( 3 ) 1343 - 1347 .
Kapil V, Haydar SMA, Pearl V, Lundberg JO, Weitzberg E, Ahluwalia A ( 2013 ) . Physiological role for nitrate-reducing oral bacteria in blood pressure control . Free Radic Biol Med vol. 55 , 93 - 100 .
Ahluwalia A, Hobbs AJ ( 2013 ) . Letter by Ahluwalia and Hobbs Regarding Article, "Nitrate-Nitrite-Nitric Oxide Pathway in Pulmonary Arterial Hypertension Therapeutics" . CIRCULATION vol. 127 , ( 2 ) E275 - E275 .
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McLean P, Ahluwalia A ( 2002 ) . Protease-activated receptor (PAR)-2 activation causes EDHF-like coronary vasodilation: selective preservation in ischemia-reperfusion injury, involvement of lipoxygenase products, VR1 receptors and C-fibers . FASEB J vol. 16 , ( 4 ) A569 - A569 .
McLean PG, Aston D, Sarkar D, Ahluwalia A ( 2002 ) . Protease-activated receptor-2 activation causes EDHF-like coronary vasodilation - Selective preservation in ischemia/reperfusion injury: Involvement of lipoxygenase products, VR1 receptors, and C-fibers . CIRC RES vol. 90 , ( 4 ) 465 - 472 .
Hesslinger C, Chen Z, Ahluwalia A, Selwood DL, Vallance P, Pfeilschifter J, Hingorani AD ( 2002 ) . Regulation of GTP Cyclohydrolase I by Estrogen . Chemistry and Biology of Pteridines and Folates ,
Scotland RS, Chauhan S, Vallance PJ, Ahluwalia A ( 2001 ) . An endothelium-derived hyperpolarizing factor-like factor moderates myogenic constriction of mesenteric resistance arteries in the absence of endothelial nitric oxide synthase-derived nitric oxide . Hypertension vol. 38 , ( 4 ) 833 - 839 .
Ahluwalia A ( 2001 ) . Nepadutant Menarini Richerche . Curr Opin Investig Drugs vol. 2 , ( 7 ) 919 - 922 .
McLean PG, Perretti M, Ahluwalia A ( 2000 ) . Kinin B<inf>1</inf> receptors and the cardiovascular system: Regulation of expression and function . Cardiovascular Research vol. 48 , ( 2 ) 194 - 210 .
McLean PG, Ahluwalia A, Perretti M ( 2000 ) . Association between kinin B<inf>1</inf> receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules . Journal of Experimental Medicine vol. 192 , ( 3 ) 367 - 380 .
Scotland RS, Vallance PJT, Ahluwalia A ( 2000 ) . Endogenous factors involved in regulation of tone of arterial vasa vasorum: Implications for conduit vessel physiology . Cardiovascular Research vol. 46 , ( 3 ) 403 - 411 .
McLean PG, Perretti M, Ahluwalia A ( 2000 ) . Kinin B<inf>1</inf> receptors as novel anti-inflammatory targets . Expert Opinion on Therapeutic Targets vol. 4 , ( 2 ) 127 - 141 .
Ahluwalia A, Scotland R ( 2000 ) . Activation of sensory C-fibres partially mediates the vascular myogenic response . FASEB JOURNAL vol. 14 , ( 4 ) A143 - A143 .
Chauhan SD, MacAllister RJ, Clapp LH, Ahluwalia A ( 2000 ) . Evidence that no may contribute to "EDHF-like" responses in rat mesenteric and hepatic small arteries . BRITISH JOURNAL OF PHARMACOLOGY vol. 129 ,
Bogle RG, McLean PG, Ahluwalia A, Vallance P ( 2000 ) . Impaired vascular sensitivity to nitric oxide in the coronary microvasculature after endotoxaemia . British Journal of Pharmacology vol. 130 , ( 1 ) 118 - 124 .
Perretti M, Ahluwalia A ( 2000 ) . The microcirculation and inflammation: Site of action for glucocorticoids . Microcirculation vol. 7 , ( 3 ) 147 - 161 .
McLean PG, Perretti M, Ahluwalia A ( 1999 ) . Inducible expression of the kinin B<inf>1</inf> receptor in the endotoxemic heart: Mechanisms of des-Arg<sup>9</sup>bradykinin-induced coronary vasodilation . British Journal of Pharmacology vol. 128 , ( 2 ) 275 - 282 .
Varsani M, MacAllister R, Ahluwalia A, Marshall I ( 1999 ) . Investigation of the alpha(1) adrenoceptor subtype(s) mediating contraction in the human internal mammary artery . BRITISH JOURNAL OF PHARMACOLOGY vol. 127 ,
McLean PG, Perretti M, Ahluwalia A ( 1999 ) . The involvement of kinin B1 receptors in the hypotensive response to endotoxin in rats . BRITISH JOURNAL OF PHARMACOLOGY vol. 127 , U62 - U62 .
Ahluwalia A, Perretti M ( 1999 ) . B<inf>1</inf> receptors as a new inflammatory target. Could this B the 1? . Trends in Pharmacological Sciences vol. 20 , ( 3 ) 100 - 104 .
Kakuyama M, Ahluwalia A, Rodrigo J, Vallance P ( 1999 ) . Cholinergic contraction is altered in nNOS knockouts: Cooperative modulation of neural bronchoconstriction by nNOS and COX . American Journal of Respiratory and Critical Care Medicine vol. 160 , ( 6 ) 2072 - 2078 .
Scotland R, Vallance P, Ahluwalia A ( 1999 ) . Endothelin alters the reactivity of vasa vasorum: Mechanisms and implications for conduit vessel physiology and pathophysiology . British Journal of Pharmacology vol. 128 , ( 6 ) 1229 - 1234 .
Scotland R, Vallance P, Ahluwalia A ( 1999 ) . On the regulation of tone in vasa vasorum . Cardiovascular Research vol. 41 , ( 1 ) 237 - 245 .
Ahluwalia A ( 1998 ) . Topical glucocorticoids and the skin-mechanisms of action: An update . Mediators of Inflammation vol. 7 , ( 3 ) 183 - 193 .
Ahluwalia A, De Felipe C, O'Brien J, Hunt SP, Perretti M ( 1998 ) . Impaired IL-1β-induced neutrophil accumulation in tachykinin NK<inf>1</inf> receptor knockout mice . British Journal of Pharmacology vol. 124 , ( 6 ) 1013 - 1015 .
Ahluwalia A, Giuliani S, Scotland R, Maggi CA ( 1998 ) . Ovalbumin-induced neurogenic inflammation in the bladder of sensitized rats . British Journal of Pharmacology vol. 124 , ( 1 ) 190 - 196 .
Kakuyama M, Vallance P, Ahluwalia A ( 1998 ) . Endothelium-dependent sensory NANC vasodilatation: Involvement of ATP, CGRP and a possible NO store . British Journal of Pharmacology vol. 123 , ( 2 ) 310 - 316 .
McLean PG, Perretti M, Ahluwalia A ( 1998 ) . Investigation of endotoxin-inducible B-1 and constitutive B-2 kinin receptors mediating coronary vasodilation in the rat isolated heart . NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY vol. 358 , ( 1 ) R335 - R335 .
Ahluwalia A, Giuliani S, Maggi CA ( 1997 ) . Allergic inflammation in the rat urinary bladder: Involvement of mast cells and C-fibres . BRITISH JOURNAL OF PHARMACOLOGY vol. 122 ,
Ahluwalia A, Bhagat K ( 1997 ) . An insight into recent developmens in understanding the mechanisms and management of septic shock . International Journal of Pharmaceutical Medicine . vol. 11 , 281 - 285 .
Scotland RS, Vallance PJ, Ahluwalia A ( 1997 ) . Comparison of vascular reactivity of porcine aorta and its vasa vasorum . CIRCULATION vol. 96 , ( 8 ) 908 - 908 .
Ahluwalia A, Vallance P ( 1997 ) . Evidence for functional responses to sensory nerve stimulation of rat small mesenteric veins . Journal of Pharmacology and Experimental Therapeutics vol. 281 , ( 1 ) 9 - 14 .
Ahluwalia A, Cellek S ( 1997 ) . Regulation of the cardiovascular system by non-adrenergic non-cholinergic nerves . Current Opinion in Nephrology and Hypertension vol. 6 , ( 1 ) 74 - 79 .
Kakuyama M, Vallance PJ, Ahluwalia A ( 1997 ) . P-30 Non-adrenergic non-cholinergic relaxation of the rabbit mesenteric small artery: Involvement of NO . Journal of Pharmacological Sciences vol. 75 ,
Ahluwalia A, Vallance PJ ( 1996 ) . Reactivity of the vasa vasorum . CIRCULATION vol. 94 , ( 8 ) 3443 - 3443 .
Perretti M, Ahluwalia A, Harris JG, Harris HJ, Wheller SK, Flower RJ ( 1996 ) . Acute inflammatory response in the mouse: Exacerbation by immunoneutralization of lipocortin 1 . British Journal of Pharmacology vol. 117 , ( 6 ) 1145 - 1154 .
Ahluwalia A, Vallance P ( 1996 ) . Interaction between sympathetic and sensory nerves in rat small arteries: Involvement of nitric oxide . American Journal of Physiology - Heart and Circulatory Physiology vol. 271 , ( 3 40-3 )
Halpern SM, Ahluwalia A, Makunura CN, Jordan S ( 1996 ) . Investigation of notalgia paraesthetica using laser Doppler velocimetry and immunohistochemistry before and after treatment with topical capsaicin . Journal of the European Academy of Dermatology and Venereology vol. 7 , ( 3 ) 228 - 234 .
Ahluwalia A, Perretti M ( 1996 ) . Involvement of bradykinin B<inf>1</inf> receptors in the polymorphonuclear leukocyte accumulation induced by IL-1β in vivo in the mouse . Journal of Immunology vol. 156 , ( 1 ) 269 - 274 .
Ahluwalia A, Newbold P, Brain SD, Flower RJ ( 1995 ) . Topical glucocorticoids inhibit neurogenic inflammation: involvement of lipocortin 1 . European Journal of Pharmacology vol. 283 , ( 1-3 ) 193 - 198 .
AHLUWALIA A, GIULIANI S, MAGGI CA ( 1995 ) . DEMONSTRATION OF A SEPTIDE-SENSITIVE INFLAMMATORY RESPONSE IN RAT SKIN . BRITISH JOURNAL OF PHARMACOLOGY vol. 114 , P41 - P41 .
AHLUWALIA A, NEWBOLD P, FLOWER RJ ( 1995 ) . TOPICAL GLUCOCORTICOIDS INHIBIT NEUROGENIC INFLAMMATION - INVOLVEMENT OF LIPOCORTIN-1 . BRITISH JOURNAL OF PHARMACOLOGY vol. 114 , P61 - P61 .
Ahluwalia A, Giuliani S, Maggi CA ( 1995 ) . Demonstration of a ‘septide‐sensitive’ inflammatory response in rat skin . British Journal of Pharmacology vol. 116 , ( 4 ) 2170 - 2174 .
Ahluwalia A, Perretti M ( 1994 ) . Calcitonin gene-related peptides modulate the acute inflammatory response induced by interleukin-1 in the mouse . European Journal of Pharmacology vol. 264 , ( 3 ) 407 - 415 .
Ahluwalia A, Mohamed RW, Flower RJ ( 1994 ) . Induction of lipocortin 1 by topical steroid in rat skin . Biochemical Pharmacology vol. 48 , ( 8 ) 1647 - 1654 .
AHLUWALIA A, FLOWER RJ ( 1994 ) . CHARACTERIZATION OF CAPSAICIN-INDUCED VASODILATION OF THE PERFUSED RABBIT EAR AND ITS MODULATION BY DEXAMETHASONE . BRITISH JOURNAL OF PHARMACOLOGY vol. 112 , U104 - U104 .
Ahluwalia A, Perretti M ( 1994 ) . Anti-inflammatory effect of prostanoids in mouse and rat skin: Evidence for a role of EP<inf>3</inf>-receptors . Journal of Pharmacology and Experimental Therapeutics vol. 268 , ( 3 ) 1526 - 1531 .
Ahluwalia A, Maggi CA, Santicioli P, Lecci A, Giuliani S ( 1994 ) . Characterization of the capsaicin‐sensitive component of cyclophosphamide‐induced inflammation in the rat urinary bladder . British Journal of Pharmacology vol. 111 , ( 4 ) 1017 - 1022 .
Perretti M, Ahluwalia A, Flowers RJ, Manzini S ( 1993 ) . Endogenous tachykinins play a role in IL-1-induced neutrophil accumulation: Involvement of NK-1 receptors . Immunology vol. 80 , ( 1 ) 73 - 77 .
AHLUWALIA A, FLOWER RJ, PERRETTI M ( 1993 ) . DUAL-ACTION OF PROSTAGLANDINS (PGS) IN THE MOUSE SKIN EDEMA TEST . BRITISH JOURNAL OF PHARMACOLOGY vol. 109 , P5 - P5 .
Ahluwalia A, Flower RJ ( 1993 ) . Effect of chronic capsaicin and guanethidine treatment on skin blood flow of the rat . Agents and Actions . vol. 38 ,
Ahluwalia A, Flower RJ ( 1993 ) . Investigations into the mechanism of vasoconstrictor action of the topical steroid betamethasone‐17‐valerate in the rat . British Journal of Pharmacology vol. 108 , ( 2 ) 544 - 548 .
Perretti M, Ahluwalia A, Harris JG, Goulding NJ, Flower RJ ( 1993 ) . Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil- dependent edema in the mouse: A qualitative comparison with an anti-CD11b monoclonal antibody . Journal of Immunology vol. 151 , ( 8 ) 4306 - 4314 .
Ahluwalia A, Flower RJ ( 1993 ) . Topical betamethasone-17-valerate inhibits heat-induced vasodilatation in man . British Journal of Dermatology vol. 128 , ( 1 ) 45 - 48 .
AHLUWALIA A, FLOWER RJ ( 1992 ) . TOPICAL STEROIDS AND ACE INHIBITORS - A COMMON LINK . BRITISH JOURNAL OF PHARMACOLOGY vol. 106 , P5 - P5 .
Ahluwalia A, Peers SH, Flower RJ ( 1992 ) . Steroid inhibition of oedema formation in the rat skin . British Journal of Pharmacology vol. 106 , ( 3 ) 628 - 631 .