Publications: Dr Kate Moore

Moore KM, Cerqueira V, MacLeod KG, Mullen P, Hayward RL, Green S, Harrison DJ, Cameron DA et al. ( 2022 ) . Collateral-resistance to estrogen and HER-activated growth is associated with modified AKT, ERα, and cell-cycle signaling in a breast cancer model . Exploration of Targeted Anti-tumor Therapy vol. 3 , 97 - 116 .

Raj D, Nikolaidi M, Garces I, Lorizio D, Castro NM, Caiafa SG, Moore K, Brown NF et al. ( 2021 ) . CEACAM7 is an effective target for CAR T-cell therapy of pancreatic ductal adenocarcinoma . Clinical Cancer Research vol. 27 , ( 5 ) 1538 - 1552 .

Caley MP, Martins VL, Moore K, Lashari M, Nissinen L, Kähäri V-M, Alexander S, Jones E et al. ( 2020 ) . Loss of Laminin α3 induces cell invasion and macrophage infiltration in cutaneous squamous cell carcinoma . British Journal of Dermatology

Moore KM, Desai A, de Luxán Delgado B, Trabulo SMD, Reader C, Brown NF, Murray ER, Brentnall A et al. ( 2020 ) . Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus . Theranostics vol. 10 , ( 7 ) 2930 - 2942 .

Reader CS, Vallath S, Steele CW, Haider S, Brentnall A, Desai A, Moore KM, Jamieson NB et al. ( 2019 ) . The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy . Journal of Pathology vol. 249 , ( 3 ) 332 - 342 .

Thomas JR, Moore KM, Sproat C, Mo S, Wolanska KI, Maldonado H, Haider S, Newman D et al. ( 2019 ) . Integrin alpha V beta 6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 100 , A39 - A39 .

Caley M, Martins V, Moore K, Lashari M, Marshall J, O'Toole E ( 2018 ) . Loss of Lam alpha 3 drives M2 macrophage differentiation in squamous cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E399 - E400 .

Fearon AE, Carter EP, Clayton NS, Wilkes EH, Baker AM, Kapitonova E, Bakhouche BA, Tanner Y et al. ( 2018 ) . PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer . Cell Reports vol. 22 , ( 9 ) 2469 - 2481 .

Caley M, Martins V, Moore K, Lashari M, Marshall J, O’Toole EA ( 2017 ) . 336 Tumour associated macrophage recruitment in SCC . Journal of Investigative Dermatology . vol. 137 ,

Caley M, Martins V, Moore K, Lashari M, Kähäri V, Nissinen L, Donaldson M, Marshall J et al. ( 2016 ) . 472 Loss of Laminin α3 drives SCC invasion via ROCK signalling . Journal of Investigative Dermatology . vol. 136 ,

Caley M, Martins V, Moore K, Lashari M, Donaldson M, Marshall JF, O'Toole EA ( 2016 ) . ROCK and Rac1 signalling in squamous cell carcinoma with loss of laminin 332 . BRITISH JOURNAL OF DERMATOLOGY . vol. 174 , E51 - E51 .

Martins VL, Caley MP, Moore K, Szentpetery Z, Marsh ST, Murrell DF, Kim MH, Avari M et al. ( 2015 ) . Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC . J Natl Cancer Inst vol. 108 , ( 1 )

Martins V, Caley M, Moore K, Szentpetery Z, Marsh S, Murrell DF, Kaehaeri V, McGrath J et al. ( 2015 ) . Skin type VII collagen acts as a tumour suppressor by regulating TGF beta and angiogenesis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 135 , S28 - S28 .

Caley M, Martins V, Marsh S, Moore K, Lashari M, Donaldson MJ, Marshall J, O'toole E ( 2015 ) . Squamous Cell Carcinoma progression and Laminin 332 . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 135 , S23 - S23 .

Caley M, Martins V, Moore K, Marshall J, O'toole E ( 2014 ) . Diverse roles for laminin 332 subunits in squamous cell carcinoma . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 134 , S19 - S19 .

Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR et al. ( 2014 ) . Therapeutic targeting of integrin αvβ6 in breast cancer . J Natl Cancer Inst vol. 106 , ( 8 )

Caley M, Martins V, Moore K, Marshall J, O'Toole E ( 2014 ) . Diverse roles for laminin-332 subunits in squamous cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 170 , E26 - E26 .

Moore K, Thomas G, Duffy S, Warwick J, Gabe R, Chou P, Ellis I, Green A et al. ( 2013 ) . Abstract P4-15-01: Integrin avb6 is a therapeutic target for high-risk breast cancer and enhances trastuzumab efficacy .

Gordon-Keylock S, Sobiesiak M, Rybtsov S, Moore K, Medvinsky A ( 2013 ) . Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs . BLOOD vol. 122 , ( 14 ) 2338 - 2345 .

Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR et al. ( 2013 ) . Abstract B046: Therapeutic targeting of integrin αvβ6 in high-risk breast cancer . b046 - b046 .

Caley MP, Martins V, Moore K, Marshall JF, O'Toole EA ( 2013 ) . Diverse roles for laminin 332 subunits in squamous cell carcinoma . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S64 - S64 .

Martins VL, Caley MP, Moore K, Szentpetery Z, Murrell DF, Kim MH, McGrath JA, Cerio R et al. ( 2013 ) . Loss of type VII collagen in cutaneous SCC increases angiogenesis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S158 - S158 .

Martins V, Caley M, Moore K, Murrell DF, McGrath JA, Chen M, Marshall JF, O'Toole EA ( 2012 ) . Loss of keratinocyte type VII collagen in SCC increases TGF-beta signalling and angiogenesis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 132 , S45 - S45 .

Martins V, Caley M, Moore K, Chen M, Marshall J, O'Toole E ( 2012 ) . Loss of type VII collagen in squamous cell carcinoma increases angiogenesis in vitro and in vivo . BRITISH JOURNAL OF DERMATOLOGY . vol. 166 , e25 - e26 .

Moore K, Hart I, Jones L, Marshall J ( 2011 ) . P2-01-05: Integrin avb6 Mediates HER2−Driven Invasion in Breast Cancer .

Martins VL, Moore K, Chen M, Marshall J, O'Toole EA ( 2011 ) . Loss of type VII collagen in SCC leads to increased invasion and TGF-beta signalling in vivo . BRITISH JOURNAL OF DERMATOLOGY . vol. 164 , 910 - 910 .

Martins V, Moore K, Chen M, Marshall J, O'Toole EA ( 2011 ) . Loss of type VII collagen in squamous cell carcinoma leads to increased invasion and TGF-beta signalling in vivo . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 131 , S33 - S33 .