Publications: Dr Kate Moore
Moore KM, Cerqueira V, MacLeod KG, Mullen P, Hayward RL, Green S, Harrison DJ, Cameron DA et al.
(
2022
)
.
Collateral-resistance to estrogen and HER-activated growth is associated with modified AKT, ERα, and cell-cycle signaling in a breast cancer model
.
Exploration of Targeted Anti-tumor Therapy
vol.
3
,
97
-
116
.
Raj D, Nikolaidi M, Garces I, Lorizio D, Castro NM, Caiafa SG, Moore K, Brown NF et al.
(
2021
)
.
CEACAM7 is an effective target for CAR T-cell therapy of pancreatic ductal adenocarcinoma
.
Clinical Cancer Research
vol.
27
,
(
5
)
1538
-
1552
.
Caley MP, Martins VL, Moore K, Lashari M, Nissinen L, Kähäri V-M, Alexander S, Jones E et al.
(
2020
)
.
Loss of Laminin α3 induces cell invasion and macrophage infiltration in cutaneous squamous cell carcinoma
.
British Journal of Dermatology
Moore KM, Desai A, de Luxán Delgado B, Trabulo SMD, Reader C, Brown NF, Murray ER, Brentnall A et al.
(
2020
)
.
Integrin αvβ6-specific therapy for pancreatic cancer developed from foot-and-mouth-disease virus
.
Theranostics
vol.
10
,
(
7
)
2930
-
2942
.
Reader CS, Vallath S, Steele CW, Haider S, Brentnall A, Desai A, Moore KM, Jamieson NB et al.
(
2019
)
.
The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy
.
Journal of Pathology
vol.
249
,
(
3
)
332
-
342
.
Thomas JR, Moore KM, Sproat C, Mo S, Wolanska KI, Maldonado H, Haider S, Newman D et al.
(
2019
)
.
Integrin alpha V beta 6-EGFR crosstalk regulates bidirectional force transmission and controls breast cancer invasion
.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
.
vol.
100
,
A39
-
A39
.
Caley M, Martins V, Moore K, Lashari M, Marshall J, O'Toole E
(
2018
)
.
Loss of Lam alpha 3 drives M2 macrophage differentiation in squamous cell carcinoma
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
178
,
E399
-
E400
.
Fearon AE, Carter EP, Clayton NS, Wilkes EH, Baker AM, Kapitonova E, Bakhouche BA, Tanner Y et al.
(
2018
)
.
PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer
.
Cell Reports
vol.
22
,
(
9
)
2469
-
2481
.
Caley M, Martins V, Moore K, Lashari M, Marshall J, O’Toole EA
(
2017
)
.
336 Tumour associated macrophage recruitment in SCC
.
Journal of Investigative Dermatology
.
vol.
137
,
Caley M, Martins V, Moore K, Lashari M, Kähäri V, Nissinen L, Donaldson M, Marshall J et al.
(
2016
)
.
472 Loss of Laminin α3 drives SCC invasion via ROCK signalling
.
Journal of Investigative Dermatology
.
vol.
136
,
Caley M, Martins V, Moore K, Lashari M, Donaldson M, Marshall JF, O'Toole EA
(
2016
)
.
ROCK and Rac1 signalling in squamous cell carcinoma with loss of laminin 332
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
174
,
E51
-
E51
.
Martins VL, Caley MP, Moore K, Szentpetery Z, Marsh ST, Murrell DF, Kim MH, Avari M et al.
(
2015
)
.
Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC
.
J Natl Cancer Inst
vol.
108
,
(
1
)
Martins V, Caley M, Moore K, Szentpetery Z, Marsh S, Murrell DF, Kaehaeri V, McGrath J et al.
(
2015
)
.
Skin type VII collagen acts as a tumour suppressor by regulating TGF beta and angiogenesis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
135
,
S28
-
S28
.
Caley M, Martins V, Marsh S, Moore K, Lashari M, Donaldson MJ, Marshall J, O'toole E
(
2015
)
.
Squamous Cell Carcinoma progression and Laminin 332
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
135
,
S23
-
S23
.
Caley M, Martins V, Moore K, Marshall J, O'toole E
(
2014
)
.
Diverse roles for laminin 332 subunits in squamous cell carcinoma
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
134
,
S19
-
S19
.
Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR et al.
(
2014
)
.
Therapeutic targeting of integrin αvβ6 in breast cancer
.
J Natl Cancer Inst
vol.
106
,
(
8
)
Caley M, Martins V, Moore K, Marshall J, O'Toole E
(
2014
)
.
Diverse roles for laminin-332 subunits in squamous cell carcinoma
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
170
,
E26
-
E26
.
Moore K, Thomas G, Duffy S, Warwick J, Gabe R, Chou P, Ellis I, Green A et al.
(
2013
)
.
Abstract P4-15-01: Integrin avb6 is a therapeutic target for high-risk breast cancer and enhances trastuzumab efficacy
.
Gordon-Keylock S, Sobiesiak M, Rybtsov S, Moore K, Medvinsky A
(
2013
)
.
Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs
.
BLOOD
vol.
122
,
(
14
)
2338
-
2345
.
Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR et al.
(
2013
)
.
Abstract B046: Therapeutic targeting of integrin αvβ6 in high-risk breast cancer
.
b046
-
b046
.
Caley MP, Martins V, Moore K, Marshall JF, O'Toole EA
(
2013
)
.
Diverse roles for laminin 332 subunits in squamous cell carcinoma
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
133
,
S64
-
S64
.
Martins VL, Caley MP, Moore K, Szentpetery Z, Murrell DF, Kim MH, McGrath JA, Cerio R et al.
(
2013
)
.
Loss of type VII collagen in cutaneous SCC increases angiogenesis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
133
,
S158
-
S158
.
Martins V, Caley M, Moore K, Murrell DF, McGrath JA, Chen M, Marshall JF, O'Toole EA
(
2012
)
.
Loss of keratinocyte type VII collagen in SCC increases TGF-beta signalling and angiogenesis
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
132
,
S45
-
S45
.
Martins V, Caley M, Moore K, Chen M, Marshall J, O'Toole E
(
2012
)
.
Loss of type VII collagen in squamous cell carcinoma increases angiogenesis in vitro and in vivo
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
166
,
e25
-
e26
.
Moore K, Hart I, Jones L, Marshall J
(
2011
)
.
P2-01-05: Integrin avb6 Mediates HER2−Driven Invasion in Breast Cancer
.
Martins VL, Moore K, Chen M, Marshall J, O'Toole EA
(
2011
)
.
Loss of type VII collagen in SCC leads to increased invasion and TGF-beta signalling in vivo
.
BRITISH JOURNAL OF DERMATOLOGY
.
vol.
164
,
910
-
910
.
Martins V, Moore K, Chen M, Marshall J, O'Toole EA
(
2011
)
.
Loss of type VII collagen in squamous cell carcinoma leads to increased invasion and TGF-beta signalling in vivo
.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
.
vol.
131
,
S33
-
S33
.