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Research

Publications: Dr Tania Marchbank

Playford RJ, Choudhry N, Kelly P, Marchbank T ( 2021 ) . Effects of bovine colostrum with or without egg on in vitro bacterial-induced intestinal damage with relevance for sibo and infectious diarrhea . Nutrients vol. 13 , ( 3 ) 1 - 16 .
Playford RJ, Marchbank T ( 2021 ) . Oral zinc carnosine reduces multi-organ damage caused by gut ischemia/reperfusion in mice . Journal of Functional Foods vol. 78 , 104361 - 104361 .
Playford R, Murray D, Marchbank T ( 2020 ) . Sa1978 ZINC CARNOSINE REDUCES INJURY IN AN IN VITRO MODEL OF GUT ISCHEMIA-REPERFUSION . Gastroenterology vol. 158 , ( 6 ) s - 486 .
Playford R, Murray D, Marchbank T ( 2020 ) . ZINC CARNOSINE REDUCES INJURY IN AN IN VITRO MODEL OF GUT ISCHEMIA-REPERFUSION . GASTROENTEROLOGY . vol. 158 , S486 - S486 .
Playford RJ, Cattell M, Marchbank T ( 2020 ) . Correction: Marked variability in bioactivity between commercially available bovine colostrum for human use; implications for clinical trials . PLoS One vol. 15 , ( 10 )
Marchbank T, Playford RJ ( 2014 ) . Colostrum: Its Health Benefits . Milk and Dairy Products as Functional Foods ,
Raymond M, Marchbank T, Moyer MP, Playford RJ, SANDERSON IR, Kruidenier L ( 2012 ) . IL-1β stimulation of CCD-18co myofibroblasts enhances repair of epithelial monolayers through Wnt-5a . American Journal of Physiology: Gastrointestinal and Liver Physiology
Marchbank T, Mahmood A, Harten S, Maxwell PH, Playford RJ ( 2011 ) . Dimethyloxalyglycine stimulates the early stages of gastrointestinal repair processes through VEGF-dependent mechanisms . Lab Invest vol. 91 , ( 12 ) 1684 - 1694 .
Marchbank T, Ojobo E, Playford CJ, Playford RJ ( 2011 ) . Reparative properties of the traditional Chinese medicine Cordyceps sinensis (Chinese caterpillar mushroom) using HT29 cell culture and rat gastric damage models of injury . Br J Nutr vol. 105 , ( 9 ) 1303 - 1310 .
Marchbank T, Davison G, Oakes JR, Ghatei MA, Patterson M, Moyer MP, Playford RJ ( 2011 ) . The nutriceutical bovine colostrum truncates the increase in gut permeability caused by heavy exercise in athletes . Am J Physiol Gastrointest Liver Physiol vol. 300 , ( 3 ) G477 - G484 .
Marchbank T, Elia G, Playford RJ ( 2009 ) . Intestinal protective effect of a commercial fish protein hydrolysate preparation . Regul Pept vol. 155 , ( 1-3 ) 105 - 109 .
Jhavar S, Brewer D, Edwards S, Kote-Jarai Z, Attard G, Clark J, Flohr P, Christmas T et al. ( 2009 ) . Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer . BJU Int vol. 103 , ( 9 ) 1256 - 1269 .
Marchbank T, Weaver G, Nilsen-Hamilton M, Playford RJ ( 2009 ) . Pancreatic secretory trypsin inhibitor is a major motogenic and protective factor in human breast milk . Am J Physiol Gastrointest Liver Physiol vol. 296 , ( 4 ) G697 - G703 .
Huang N, Bethell D, Card C, Cornish J, Marchbank T, Wyatt D, Mabery K, Playford R ( 2008 ) . Bioactive recombinant human lactoferrin, derived from rice, stimulates mammalian cell growth . In Vitro Cell Dev Biol Anim vol. 44 , ( 10 ) 464 - 471 .
Marchbank T, Limdi JK, Mahmood A, Elia G, Playford RJ ( 2008 ) . Clinical trial: protective effect of a commercial fish protein hydrolysate against indomethacin (NSAID)-induced small intestinal injury . Aliment Pharmacol Ther vol. 28 , ( 6 ) 799 - 804 .
Marchbank T, K Limdi J, Mahmood A, Elia G, J Playford R ( 2008 ) . Clinical trial: protective effect of a commercial fish protein hydrolysate against indomethacin (NSAID)-induced small intestinal injury . Aliment Pharmacol Ther
Marchbank T, Mahmood A, Fitzgerald AJ, Domin J, Butler M, Goodlad RA, Elia G, Cox HM et al. ( 2007 ) . Human pancreatic secretory trypsin inhibitor stabilizes intestinal mucosa against noxious agents . Am J Pathol vol. 171 , ( 5 ) 1462 - 1473 .
Mahmood A, FitzGerald AJ, Marchbank T, Ntatsaki E, Murray D, Ghosh S, Playford RJ ( 2007 ) . Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes . Gut vol. 56 , ( 2 ) 168 - 175 .
Playford RJ, Belo A, Poulsom R, Fitzgerald AJ, Harris K, Pawluczyk I, Ryon J, Darby T et al. ( 2006 ) . Effects of mouse and human lipocalin homologues 24p3/lcn2 and neutrophil gelatinase-associated lipocalin on gastrointestinal mucosal integrity and repair . Gastroenterology vol. 131 , ( 3 ) 809 - 817 .
Cibrián D, Ajamieh H, Berlanga J, León OS, Alba JS, Kim MJ-T, Marchbank T, Boyle JJ et al. ( 2006 ) . Use of growth-hormone-releasing peptide-6 (GHRP-6) for the prevention of multiple organ failure . Clin Sci (Lond) vol. 110 , ( 5 ) 563 - 573 .
Belo A, Marchbank T, Fitzgerald A, Ghosh S, Playford RJ ( 2006 ) . Gastroprotective effects of oral nucleotide administration . Gut vol. 55 , ( 2 ) 165 - 171 .
Fitzgerald AJ, Rai PS, Marchbank T, Taylor GW, Ghosh S, Ritz BW, Playford RJ ( 2005 ) . Reparative properties of a commercial fish protein hydrolysate preparation . Gut vol. 54 , ( 6 ) 775 - 781 .
FitzGerald AJ, Pu M, Marchbank T, Westley BR, May FEB, Boyle J, Yadollahi-Farsani M, Ghosh S et al. ( 2004 ) . Synergistic effects of systemic trefoil factor family 1 (TFF1) peptide and epidermal growth factor in a rat model of colitis . Peptides vol. 25 , ( 5 ) 793 - 801 .
Marchbank T, Boulton R, Hansen H, Playford RJ ( 2002 ) . Human transforming growth factor alpha (TGF-alpha) is digested to a smaller (1-43), less biologically active, form in acidic gastric juice . Gut vol. 51 , ( 6 ) 787 - 792 .
Marchbank T, Cox HM, Goodlad RA, Giraud AS, Moss SF, Poulsom R, Wright NA, Jankowski J et al. ( 2001 ) . Effect of ectopic expression of rat trefoil factor family 3 (intestinal trefoil factor) in the jejunum of transgenic mice . J Biol Chem vol. 276 , ( 26 ) 24088 - 24096 .
Playford RJ, MacDonald CE, Calnan DP, Floyd DN, Podas T, Johnson W, Wicks AC, Bashir O et al. ( 2001 ) . Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability . Clin Sci (Lond) vol. 100 , ( 6 ) 627 - 633 .
Caballero ME, Berlanga J, Ramirez D, Lopez-Saura P, Gozalez R, Floyd DN, Marchbank T, Playford RJ ( 2001 ) . Epidermal growth factor reduces multiorgan failure induced by thioacetamide . Gut vol. 48 , ( 1 ) 34 - 40 .
Calnan DP, Fagbemi A, Berlanga-Acosta J, Marchbank T, Sizer T, Lakhoo K, Edwards AD, Playford RJ ( 2000 ) . Potency and stability of C terminal truncated human epidermal growth factor . Gut vol. 47 , ( 5 ) 622 - 627 .
Playford RJ, Wright NA, Marchbank T ( 2000 ) . Endogenous peptides and peptide therapy in gut defense and repair . Drug News Perspect vol. 13 , ( 6 ) 330 - 336 .
Calnan DP, Westley BR, May FE, Floyd DN, Marchbank T, Playford RJ ( 1999 ) . The trefoil peptide TFF1 inhibits the growth of the human gastric adenocarcinoma cell line AGS . J Pathol vol. 188 , ( 3 ) 312 - 317 .
Playford RJ, Floyd DN, Macdonald CE, Calnan DP, Adenekan RO, Johnson W, Goodlad RA, Marchbank T ( 1999 ) . Bovine colostrum is a health food supplement which prevents NSAID induced gut damage . Gut vol. 44 , ( 5 ) 653 - 658 .
Marchbank T, Westley BR, May FE, Calnan DP, Playford RJ ( 1998 ) . Dimerization of human pS2 (TFF1) plays a key role in its protective/healing effects . J Pathol vol. 185 , ( 2 ) 153 - 158 .
Playford RJ, Marchbank T, Mandir N, Higham A, Meeran K, Ghatei MA, Bloom SR, Goodlad RA ( 1998 ) . Effects of keratinocyte growth factor (KGF) on gut growth and repair . J Pathol vol. 184 , ( 3 ) 316 - 322 .
Marchbank T, Freeman TC, Playford RJ ( 1998 ) . Human pancreatic secretory trypsin inhibitor. Distribution, actions and possible role in mucosal integrity and repair . Digestion vol. 59 , ( 3 ) 167 - 174 .
McKenzie C, Marchbank T, Playford RJ, Otto W, Thim L, Parsons ME ( 1997 ) . Pancreatic spasmolytic polypeptide protects the gastric mucosa but does not inhibit acid secretion or motility . Am J Physiol vol. 273 , ( 1 Pt 1 ) G112 - G117 .
Playford RJ, Marchbank T, Goodlad RA, Chinery RA, Poulsom R, Hanby AM ( 1996 ) . Transgenic mice that overexpress the human trefoil peptide pS2 have an increased resistance to intestinal damage . Proc Natl Acad Sci U S A vol. 93 , ( 5 ) 2137 - 2142 .
Marchbank T, Chinery R, Hanby AM, Poulsom R, Elia G, Playford RJ ( 1996 ) . Distribution and expression of pancreatic secretory trypsin inhibitor and its possible role in epithelial restitution . Am J Pathol vol. 148 , ( 3 ) 715 - 722 .
Marchbank T, Goodlad RA, Lee CY, Playford RJ ( 1995 ) . Luminal epidermal growth factor is trophic to the small intestine of parenterally fed rats . Clin Sci (Lond) vol. 89 , ( 2 ) 117 - 120 .
Playford RJ, Marchbank T, Calnan DP, Calam J, Royston P, Batten JJ, Hansen HF ( 1995 ) . Epidermal growth factor is digested to smaller, less active forms in acidic gastric juice . Gastroenterology vol. 108 , ( 1 ) 92 - 101 .
Playford RJ, Marchbank T, Chinery R, Evison R, Pignatelli M, Boulton RA, Thim L, Hanby AM ( 1995 ) . Human spasmolytic polypeptide is a cytoprotective agent that stimulates cell migration . Gastroenterology vol. 108 , ( 1 ) 108 - 116 .