Publications: Dr Sarah Finer
Jacobs BM, Stow D, Hodgson S, Zöllner J, Samuel M, Kanoni S, Bidi S, Walter K et al.
(
2024
)
.
Genetic architecture of routinely acquired blood tests in a British South Asian cohort
.
Nature Communications
vol.
15
,
(
1
)
Gomez EA, De Matteis R, Udomjarumanee P, Team GAHR, Akhtar S, Anwar M, Arciero E, Asgar O et al.
(
2024
)
.
An LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections
.
Blood
vol.
144
,
(
4
)
420
-
434
.
Samuel M, Park RY, Eastwood SV, Eto F, Morton CE, Stow D, Bacon S, Mehrkar A et al.
(
2024
)
.
Trends in weight gain recorded in English primary care before and during the Coronavirus-19 pandemic: An observational cohort study using the OpenSAFELY platform
.
PLOS Medicine
vol.
21
,
(
6
)
Samuel M, Park RY, Eastwood SV, Eto F, Morton CE, Stow D, Bacon S, Goldacre B et al.
(
2024
)
.
Weight trends amongst adults with diabetes or hypertension during the COVID-19 pandemic: an observational study using OpenSAFELY
.
British Journal of General Practice
vol.
74
,
(
748
)
Calderón-Larrañaga S, Greenhalgh T, Finer S, Clinch M
(
2024
)
.
What does social prescribing look like in practice? A qualitative case study informed by practice theory
.
Social Science & Medicine
vol.
343
,
Meng X, Navoly G, Giannakopoulou O, Levey DF, Koller D, Pathak GA, Koen N, Lin K et al.
(
2024
)
.
Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference
.
Nature Genetics
vol.
56
,
(
2
)
222
-
233
.
Ahmad TA, Dayem Ullah AZ, Chelala C, Gopal DP, Eto F, Henkin R, Samuel M, Finer S et al.
(
2024
)
.
Prevalence of multimorbidity in survivors of 28 cancer sites: an English nationwide cross-sectional study
.
American Journal of Cancer Research
vol.
14
,
(
2
)
880
-
896
.
Garrod-Ketchley C, d’Algue LM, Littlewood K, Hood G, Worthington A, Pattrick M, Sutcliffe C, Valla Z et al.
(
2023
)
.
The generation of senescent-like CD4+ EMRA T cells in T2D and their contribution to poor COVID-19 vaccine responses
.
Discovery Immunology
vol.
3
,
(
1
)
Law JH, Sultan N, Finer S, Fudge N
(
2023
)
.
Advancing the communication of genetic risk for cardiometabolic diseases: a critical interpretive synthesis
.
BMC Medicine
vol.
21
,
(
1
)
Magavern EF, Jacobs B, Warren H, Finocchiaro G, Finer S, Van Heel DA, Smedley D, Caulfield MJ
(
2023
)
.
CYP2C19 genotype prevalence and association with recurrent myocardial infarction in British-South Asians treated with clopidogrel
.
European Heart Journal
vol.
44
,
(
Supplement_2
)
Eto F, Samuel M, Henkin R, Mahesh M, Ahmad T, Angdembe A, McAllister-Williams RH, Missier P et al.
(
2023
)
.
Ethnic differences in early onset multimorbidity and associations with health service use, long-term prescribing, years of life lost, and mortality: A cross-sectional study using clustering in the UK Clinical Practice Research Datalink
.
PLOS Medicine
vol.
20
,
(
10
)
Malawsky DS, van Walree E, Jacobs BM, Heng TH, Huang QQ, Sabir AH, Rahman S, Sharif SM et al.
(
2023
)
.
Influence of autozygosity on common disease risk across the phenotypic spectrum
.
Cell
vol.
186
,
(
21
)
4514
-
4527.e14
.
Magavern EF, Jacobs B, Warren H, Finocchiaro G, Finer S, van Heel DA, Team GHR, Smedley D et al.
(
2023
)
.
CYP2C19 Genotype Prevalence and Association With Recurrent Myocardial Infarction in British–South Asians Treated With Clopidogrel
.
JACC Advances
vol.
2
,
(
7
)
Zöllner J, Finer S, Linton KJ, van Heel DA, Williamson C, Dixon PH
(
2023
)
.
Rare variant contribution to cholestatic liver disease in a South Asian population in the United Kingdom
.
Scientific Reports
vol.
13
,
(
1
)
Burley K, Fitzgibbon L, van Heel D, Team GHR, Akhtar S, Anwar M, Arciero E, Asgar O et al.
(
2023
)
.
PIK3R3 is a candidate regulator of platelet count in people of Bangladeshi ancestry
.
Research and Practice in Thrombosis and Haemostasis
vol.
7
,
(
4
)
Fejzo M, Zöllner J, Pujol-Gualdo N, Laisk T, Team EBR, Finer S, van Heel D, Team GHR et al.
(
2023
)
.
GDF15, Genetic Risk Factor for Hyperemesis Gravidarum, Inversely Associated With Pregnancy Weight Gain [ID: 1358449]
.
Obstetrics and Gynecology
vol.
141
,
(
5S
)
73s
-
74s
.
Dambha-Miller H, Farmer A, Nirantharakumar K, Jackson T, Yau C, Walker L, Buchan I, Finer S et al.
(
2023
)
.
<p>Artificial Intelligence for Multiple Long-term conditions (AIM): A consensus statement from the NIHR AIM consortia</p>
.
NIHR Open Research
vol.
3
,
Calderón-Larrañaga S, Greenhalgh T, Clinch M, Robson J, Dostal I, Eto F, Finer S
(
2023
)
.
Unravelling the potential of social prescribing in individual-level type 2 diabetes prevention: a mixed-methods realist evaluation
.
BMC Medicine
vol.
21
,
(
1
)
Dobson R, Jacobs B, Marshall C
(
2023
)
.
Polygenic risk score prediction of Multiple Sclerosis in individuals of South Asian ancestry
.
Brain Communications
Wang Y, Namba S, Lopera E, Kerminen S, Tsuo K, Läll K, Kanai M, Zhou W et al.
(
2023
)
.
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts
.
Cell Genomics
vol.
3
,
(
1
)
Calderon-Larranaga S, Greenhalgh T, Clinch M, Eto F, Robson J, Dostal I, Finer S
(
2023
)
.
Unravelling the potential of social prescribing in type 2 diabetes prevention: A mixed methods realist evaluation
.
DIABETIC MEDICINE
.
vol.
40
,
Kremer R, Raza SM, Eto F, Casement J, Atallah C, Finer S, Lendrem D, Barnes M et al.
(
2022
)
.
Tracking trajectories of multiple long-term conditions using dynamic patient-cluster associations
.
Conference:
2022 IEEE International Conference on Big Data (Big Data)
vol.
00
,
4390
-
4399
.
Papoutsi C, Hargreaves D, Hagell A, Hounsome N, Skirrow H, Muralidhara K, Colligan G, Ferrey A et al.
(
2022
)
.
Implementation and delivery of group consultations for young people with diabetes in socioeconomically deprived, ethnically diverse settings
.
BMC Medicine
vol.
20
,
(
1
)
Kanai M, Elzur R, Zhou W, Initiative GBM-A, Zhou W, Kanai M, Wu K-HH, Rasheed H et al.
(
2022
)
.
Meta-analysis fine-mapping is often miscalibrated at single-variant resolution
.
Cell Genomics
vol.
2
,
(
12
)
Zhou W, Kanai M, Wu K-HH, Rasheed H, Tsuo K, Hirbo JB, Wang Y, Bhattacharya A et al.
(
2022
)
.
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease
.
Cell Genomics
vol.
2
,
(
10
)
BYH L, A W, S F, FR D, JA T, Soares AG, K W, P S et al.
(
2022
)
.
MC3R links nutritional state to childhood growth and the timing of puberty
.
Huang QQ, Sallah N, Dunca D, Trivedi B, Hunt KA, Hodgson S, Lambert SA, Arciero E et al.
(
2022
)
.
Transferability of genetic loci and polygenic scores for cardiometabolic traits in British Pakistani and Bangladeshi individuals
.
Nature Communications
vol.
13
,
(
1
)
Nguyen H, Solomonson M, Palotie A, Davis L, Lee S, Priest J, Sankaran VG, van Heel D et al.
(
2022
)
.
A first update on mapping the human genetic architecture of COVID-19
.
Nature
vol.
608
,
(
7921
)
e1
-
e10
.
Papoutsi C, Hargreaves D, Hagell A, Hounsome N, Skirrow H, Muralidhara K, Colligan G, Vijayaraghavan S et al.
(
2022
)
.
Group clinics for young adults living with diabetes in an ethnically diverse, socioeconomically deprived population: mixed-methods evaluation
.
Health and Social Care Delivery Research
vol.
10
,
(
25
)
1
-
124
.
Hodgson S, Huang QQ, Sallah N, Team GHR, Griffiths CJ, Newman WG, Trembath RC, Wright J et al.
(
2022
)
.
Integrating polygenic risk scores in the prediction of type 2 diabetes risk and subtypes in British Pakistanis and Bangladeshis: A population-based cohort study
.
PLOS Medicine
vol.
19
,
(
5
)
Calderón‐Larrañaga S, Greenhalgh T, Finer S, Clinch M
(
2022
)
.
What does the literature mean by social prescribing? A critical review using discourse analysis
.
Sociology of Health & Illness
vol.
44
,
(
4-5
)
848
-
868
.
Baillie JK, Begg C, Clohisey Hendry S, Hinds C, Horby P, Knight J, Ling L, Maslove D et al.
(
2022
)
.
Whole-genome sequencing reveals host factors underlying critical COVID-19
.
Nature
vol.
607
,
(
7917
)
97
-
103
.
Pervjakova N, Moen G-H, Borges M-C, Ferreira T, Cook JP, Allard C, Beaumont RN, Canouil M et al.
(
2022
)
.
Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes
.
Human Molecular Genetics
vol.
31
,
(
19
)
3377
-
3391
.
Mathur R, Hull SA, Hodgson S, Finer S
(
2022
)
.
Characterisation of type 2 diabetes subgroups and their association with ethnicity and clinical outcomes: a UK real-world data study using the East London Database
.
British Journal of General Practice
vol.
72
,
(
719
)
Nongmaithem SS, Beaumont RN, Dedaniya A, Wood AR, Ogunkolade B-W, Hassan Z, Krishnaveni GV, Kumaran K et al.
(
2022
)
.
Babies of South Asian and European Ancestry Show Similar Associations With Genetic Risk Score for Birth Weight Despite the Smaller Size of South Asian Newborns
.
Diabetes
vol.
71
,
(
4
)
821
-
836
.
Ogunkolade BW, Adaikalakoteswari A, Cardoso SR, Lowe R, Patel N, Rakyan V, Finer S, Wabitsch M et al.
(
2022
)
.
An integrative epi-transcriptomic approach identifies the human cartilage chitinase 3-like protein 2 (CHI3L2) as a potential mediator of B12 deficiency in adipocytes
.
Epigenetics
Hodgson S, Huang QQ, Sallah N, Lumbers RT, Kuchenbaecker K, van Heel DA, Mathur R, Griffiths CJ et al.
(
2022
)
.
A type 2 diabetes polygenic risk score enhances prediction of incident diabetes compared to QDiabetes alone in British Pakistani and Bangladeshis: Results from the Genes and Health study
.
DIABETIC MEDICINE
.
vol.
39
,
Calderon-Larranaga S, Clinch M, Finer S
(
2022
)
.
Social prescribing: A new partner for the NHS Diabetes Prevention Programme?
.
DIABETIC MEDICINE
.
vol.
39
,
Lau EYM, Carroll E, Callender L, Finer S, Henson S
(
2022
)
.
The impact of type 2 diabetes on immunosenescence and functional immunity
.
CLINICAL AND EXPERIMENTAL ALLERGY
.
vol.
52
,
1037
-
1037
.
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al.
(
2021
)
.
Risk Factors for Developing COVID-19: A Population-Based Longitudinal Study (COVIDENCE UK)
.
Thorax
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young KS, Davies MR et al.
(
2021
)
.
Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
.
Thorax
vol.
77
,
(
9
)
900
-
912
.
Sobczyńska-Malefora A, Yajnik CS, Harrington DJ, Hitman GA, Finer S
(
2021
)
.
Vitamin B12 and Folate Markers Are Associated with Insulin Resistance During the Third Trimester of Pregnancy in South Asian Women, Living in the United Kingdom, with Gestational Diabetes and Normal Glucose Tolerance
.
Journal of Nutrition
vol.
152
,
(
1
)
163
-
170
.
Lam BYH, Williamson A, Finer S, Day FR, Tadross JA, Gonçalves Soares A, Wade K, Sweeney P et al.
(
2021
)
.
MC3R links nutritional state to childhood growth and the timing of puberty
.
Nature
vol.
599
,
(
7885
)
436
-
441
.
D’Antonio M, Nguyen JP, Arthur TD, Matsui H, Neale BM, Daly M, Ganna A, Stevens C et al.
(
2021
)
.
SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues
.
Cell Reports
vol.
37
,
(
7
)
Callender L, Carroll E, Ketchley-Garrod C, Schroth J, BYSTROM J, Berryman V, Pattrick M, Campbell-Richards D et al.
(
2021
)
.
Altered nutrient uptake causes mitochondrial dysfunction in senescent CD8+ EMRA T cells during type 2 diabetes
.
Frontiers in Aging
Neves MR, Daley BJ, Hitman GA, Huda MSB, McLachlan S, Finer S, Marsh W
(
2021
)
.
Causal Dynamic Bayesian Networks for the Management of Glucose Control in Gestational Diabetes
.
Conference:
2021 IEEE 9th International Conference on Healthcare Informatics (ICHI)
vol.
00
,
31
-
40
.
van Blokland IV, Lanting P, Ori APS, Vonk JM, Warmerdam RCA, Herkert JC, Boulogne F, Claringbould A et al.
(
2021
)
.
Using symptom-based case predictions to identify host genetic factors that contribute to COVID-19 susceptibility
.
PLOS ONE
vol.
16
,
(
8
)
Edwards AE, Vathenen R, Henson SM, Finer S, Gunganah K
(
2021
)
.
Acute hyperglycaemic crisis after vaccination against COVID‐19: A case series
.
Diabetic Medicine
vol.
38
,
(
11
)
Niemi MEK, Karjalainen J, Liao RG, Neale BM, Daly M, Ganna A, Davis L, Lee S et al.
(
2021
)
.
Mapping the human genetic architecture of COVID-19
.
Nature
vol.
600
,
(
7889
)
472
-
477
.
Calderón-Larrañaga S, Milner Y, Clinch M, Greenhalgh T, Finer S
(
2021
)
.
Tensions and opportunities in social prescribing. developing a framework to facilitate its implementation and evaluation in primary care: a realist review
.
BJGP Open
vol.
5
,
(
3
)
Calderón-Larrañaga S, Clinch M, Greenhalgh T, Finer S
(
2021
)
.
Could social prescribing contribute to type 2 diabetes prevention in people at high risk? Protocol for a realist, multilevel, mixed methods review and evaluation
.
BMJ Open
vol.
11
,
(
4
)
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al.
(
2021
)
.
Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
.
MedRvx
Mclachlan S, Kyrimi E, Daley BJ, Dube K, Marsden M, Finer S, Hitman GA, Fenton NE
(
2020
)
.
Incorporating Clinical Decisions into Standardised Caremaps
.
Conference:
2020 IEEE International Conference on Healthcare Informatics (ICHI)
vol.
00
,
1
-
2
.
Papoutsi C, Hargreaves D, Colligan G, Hagell A, MacKinnon S, Vijayaraghavan S, Greenhalgh T, Finer S
(
2020
)
.
G416 Sociodemographic and clinical predictors of attendance at group clinics for young adults with diabetes (together study)
.
Conference:
BSPEDa150.1
-
a1a150
.
Severe Covid-19 GWAS Group, Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernández J et al.
(
2020
)
.
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
.
N Engl J Med
vol.
383
,
(
16
)
1522
-
1534
.
Saravanan P, Group DIPW, Group MMCS, College of Obstetricians and Gynaecologists, Magee LA, Banerjee A, Coleman MA, Von Dadelszen P et al.
(
2020
)
.
Gestational diabetes: opportunities for improving maternal and child health
.
The Lancet Diabetes & Endocrinology
vol.
8
,
(
9
)
793
-
800
.
McGregor TL, Hunt KA, Yee E, Mason D, Nioi P, Ticau S, Pelosi M, Loken PR et al.
(
2020
)
.
Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria
.
eLife
vol.
9
,
Finer S, Martin HC, Khan A, Hunt KA, MacLaughlin B, Ahmed Z, Ashcroft R, Durham C et al.
(
2019
)
.
Cohort Profile: East London Genes & Health (ELGH), a community-based population genomics and health study in British Bangladeshi and British Pakistani people
.
International Journal of Epidemiology
vol.
49
,
(
1
)
20
-
21i
.
Ong SE, Clinch M, Mathur R, Perel P, Chia KS, Legido-Quigley H, Finer S
.
Improving Type 2 Diabetes prevention and care in England – what can healthcare transformation achieve?: A qualitative study
.
International Journal of Integrated Care
.
vol.
19
,
Lau EYM, Carroll EC, Callender LA, Hood GA, Berryman V, Pattrick M, Finer S, Hitman GA et al.
(
2019
)
.
Type 2 diabetes is associated with the accumulation of senescent T cells
.
Clinical & Experimental Immunology
Papoutsi C, COLLIGAN G, Hagell A, Hargreaves D, Marshall M, VIJAYARAGHAVAN S, Greenhalgh T, FINER S
(
2019
)
.
Promises and perils of group clinics for young people living with diabetes: a realist review
.
Diabetes Care
Fottrell E, Ahmed N, Nahar B, Shaha SK, Kuddus A, Grijalva-Eternod CS, Nahar T, Fall C et al.
(
2018
)
.
Growth and body composition of children aged 2–4 years after exposure to community mobilisation women’s groups in Bangladesh
.
Journal of Epidemiology & Community Health
vol.
72
,
(
10
)
Finer S, Robb P, Cowan K, Daly A, Shah K, Farmer A
(
2018
)
.
Setting the top 10 research priorities to improve the health of people with Type 2 diabetes: a Diabetes UK–James Lind Alliance Priority Setting Partnership
.
Diabetic Medicine
vol.
35
,
(
7
)
862
-
870
.
FINER S, Robb P, Cowan K, Daly A, Robertson E, Farmer A
(
2017
)
.
Top ten research priorities for type 2 diabetes: results from the Diabetes UK–James Lind Alliance Priority Setting Partnership
.
Lancet Diabetes and Endocrinology
Gassasse Z, Smith D, FINER S, Gallo V
(
2017
)
.
Association between urbanisation and type 2 diabetes: an ecological study
.
BMJ Global Health
Papoutsi C, Hargreaves D, Colligan G, Hagell A, Patel A, Campbell-Richards D, Viner R, Vijayaraghavan S et al.
(
2017
)
.
Group clinics for young adults with diabetes in an ethnically diverse, socioeconomically deprived setting (TOGETHER study): protocol for a realist review, co-design and mixed methods, participatory evaluation of a new care model
.
BMJ Open
Finer S, Lowe R, Ogunkolade W, Bhowmik B, Hussain A, Khan AKA, Rakyan V, Hitman GA
(
2017
)
.
The influence of maternal and offspring environment on genome-wide methylation of the offspring in Bangladesh
.
Manchester Central, Manchester
,
from:
08/03/2017
to:
10/03/2017
,
vol.
34
,
pp.
20
-
21
.
Abstract:
java.sql.Clob
org.hibernate.engine.jdbc.WrappedClob
java.io.Serializable
,
Finer S, LOWE R, Ogunkolade BW, Pervin S, Mathews C, Smart M, Alam DS, Hitman GA
(
2016
)
.
Is famine exposure during developmental life in rural Bangladesh associated with a metabolic and epigenetic signature in young adulthood? A historical cohort study
.
BMJ Open
Kage A, Cowan F, Kempley S, Finer S, Hogg M, Hitman G, Shah D
(
2016
)
.
HEAD CIRCUMFERENCE IS DIRECTLY RELATED TO SPECIFIC LINEAR MEASUREMENTS OF CEREBRAL STRUCTURES IN A LOCAL EAST LONDON POPULATION OF WELL NEWBORNS OF SOUTH ASIAN DIASPORA
.
EUROPEAN JOURNAL OF PEDIATRICS
.
vol.
175
,
1676
-
1676
.
Finer S
(
2016
)
.
Studying Fetal Programming in South Asian Populations: The GIFTS Study
.
ANNALS OF NUTRITION AND METABOLISM
vol.
69
,
(
2
)
104
-
105
.
Barry E, Roberts S, Finer S, Vijayaraghavan S, Greenhalgh T
(
2015
)
.
Time to question the NHS diabetes prevention programme
.
The BMJ
vol.
351
,
Greenhalgh T, Clinch M, Afsar N, Choudhury Y, Sudra R, Campbell-Richards D, Claydon A, Hitman GA et al.
(
2015
)
.
Socio-cultural influences on the behaviour of South Asian women with diabetes in pregnancy: qualitative study using a multi-level theoretical approach
.
BMC Medicine
vol.
13
,
(
1
)
Adaikalakoteswari A, Finer S, Voyias PD, McCarthy CM, Vatish M, Moore J, Smart-Halajko M, Bawazeer N et al.
(
2015
)
.
Vitamin B12 insufficiency induces cholesterol biosynthesis by limiting s-adenosylmethionine and modulating the methylation of SREBF1 and LDLR genes
.
Clinical Epigenetics
vol.
7
,
(
1
)
Murphy H, Finer S
(
2015
)
.
Gestational Diabetes Mellitus and the Offspring—Jack and Jill Are Different Still
.
Diabetes Care
vol.
38
,
(
3
)
345
-
346
.
Finer S
(
2015
)
.
Fetal programming via maternal diabetes: the controversy continues
.
Diabetic Medicine
vol.
32
,
(
3
)
291
-
294
.
Hillman SL, Finer S, Smart MC, Mathews C, Lowe R, Rakyan VK, Hitman GA, Williams DJ
(
2015
)
.
Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates
.
Epigenetics
vol.
10
,
(
1
)
50
-
61
.
Finer S, Mathews C, Lowe R, Smart M, Hillman S, Foo L, Sinha A, Williams D et al.
(
2015
)
.
Maternal gestational diabetes is associated with genome-wide DNA methylation variation in placenta and cord blood of exposed offspring
.
Human molecular genetics
vol.
24
,
(
11
)
3021
-
3029
.
Adaikalakoteswari A, Finer S, Voyias PD, McCarthy C, Moore J, Smart-Halajko M, Bawazeer N, Al-Daghri NM et al.
(
2015
)
.
Vitamin B12 deficiency induces cholesterol biosynthesis by limiting S-adenosyl methionine and altering the methylation of SREBF1 and LDLR genes
.
DIABETIC MEDICINE
vol.
32
,
30
-
30
.
Finer S, Saravanan P, Hitman G, Yajnik C
(
2014
)
.
The role of the one-carbon cycle in the developmental origins of Type 2 diabetes and obesity
.
Diabet Med
vol.
31
,
(
3
)
263
-
272
.
Finer S, Iqbal S, Mathews C, Ogunkolade BW, Smart M, Alam D, Hitman G
(
2014
)
.
DNA methylation variants in young adult offspring exposed to famine during postnatal life in Bangladesh
.
The Lancet
vol.
383
,
Hitman GA, Finer S
(
2014
)
.
To tweet or not to tweet
.
Diabet Med
vol.
31
,
(
2
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