Publications: Mr Vikas Kapil

Magavern EF, Kapil V, Saxena M, Gupta A, Caulfield MJ ( 2024 ) . Use of Genomics to Develop Novel Therapeutics and Personalize Hypertension Therapy . Arteriosclerosis Thrombosis and Vascular Biology

del Arroyo AG, Patel A, Abbott TEF, Begum S, Dias P, Somanath S, Middleditch A, Cleland S et al. ( 2024 ) . Preoperative N-terminal pro-B-type natriuretic peptide and myocardial injury after stopping or continuing renin–angiotensin system inhibitors in noncardiac surgery: a prespecified analysis of a phase 2 randomised controlled multicentre trial . British Journal of Anaesthesia

Faust SN, Haynes R, Jones CE, Staplin N, Whittaker E, Jaki T, Juszczak E, Spata E et al. ( 2024 ) . Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet Child & Adolescent Health vol. 8 , ( 3 ) 190 - 200 .

Lewis P, George J, Kapil V, Poulter NR, Partridge S, Goodman J, Faconti L, McCormack T et al. ( 2024 ) . Adult hypertension referral pathway and therapeutic management: British and Irish Hypertension Society position statement . Journal of Human Hypertension vol. 38 , ( 1 ) 3 - 7 .

Faconti L, Kulkarni S, Delles C, Kapil V, Lewis P, Glover M, MacDonald TM, Wilkinson IB ( 2023 ) . Diagnosis and management of primary hyperaldosteronism in patients with hypertension: a practical approach endorsed by the British and Irish Hypertension Society . Journal of Human Hypertension vol. 38 , ( 1 ) 8 - 18 .

Thein PM, Guerreiro C, Fhadil S, Hamedi N, Zalin A, Kapil V, Choudry F, Abhishek J et al. ( 2023 ) . Risk factor burden in familial hypercholesterolaemia with early onset coronary artery disease . European Heart Journal vol. 44 , ( Supplement_2 )

Ackland G ( 2023 ) . Discontinuation vs. continuation of renin–angiotensin system inhibition before non-cardiac surgery: the SPACE trial . European Heart Journal Article ehad716 ,

Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H et al. ( 2023 ) . Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet Diabetes & Endocrinology vol. 11 , ( 12 ) 905 - 914 .

Shabbir A, Chhetri I, Khambata RS, Parakaw T, Lau C, Aubdool MABN, Massimo G, Dyson N et al. ( 2023 ) . A double-blind, randomised, placebo-controlled parallel study to investigate the effect of sex and dietary nitrate on COVID-19 vaccine-induced vascular dysfunction in healthy men and women: protocol of the DiNOVasc-COVID-19 study . Trials vol. 24 , ( 1 )

Charchar FJ, Prestes PR, Mills C, Ching SM, Neupane D, Marques FZ, Sharman JE, Vogt L et al. ( 2023 ) . Lifestyle management of hypertension: International Society of Hypertension position paper endorsed by the World Hypertension League and European Society of Hypertension . Journal of Hypertension vol. 42 , ( 1 ) 23 - 49 .

Lobo MD, Rull G, Saxena M, Kapil V ( 2023 ) . Selecting patients for interventional procedures to treat hypertension . Blood Pressure vol. 32 , ( 1 )

Thein P, Guerreiro C, Fhadil S, Hamedi N, Zalin A, Kapil V, Choudhry F, Joshi A et al. ( 2023 ) . Risk Factor Burden in Familial Hypercholesterolaemia With Early Onset Coronary Artery Disease . Heart Lung and Circulation vol. 32 ,

Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H et al. ( 2023 ) . Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet vol. 401 , ( 10387 ) 1499 - 1507 .

Maniero C, Ng SM, Collett G, Godec T, Siddiqui I, Antoniou S, Kumar A, Janmohamed A et al. ( 2023 ) . Differential impact of COVID-19 on mental health and burnout . Occupational Medicine vol. 74 , ( 1 ) 45 - 52 .

Siddiqui I, Gupta J, Collett G, McIntosh I, Komodromos C, Godec T, Ng S, Maniero C et al. ( 2023 ) . Perceived workplace support and mental health, well-being and burnout among health care professionals during the COVID-19 pandemic: a cohort analysis . CMAJ Open vol. 11 , ( 1 ) e191 - e200 .

Khanji MY, Collett G, Godec T, Maniero C, Ng SM, Siddiqui I, Gupta J, Kapil V et al. ( 2023 ) . Improved lifestyle is associated with improved depression, anxiety and well-being over time in UK healthcare professionals during the COVID-19 pandemic: insights from the CoPE-HCP cohort study . General Psychiatry vol. 36 , ( 1 )

Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC et al. ( 2023 ) . Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans . Journal of Clinical Investigation vol. 133 , ( 2 )

Robbins AJ, Bakri NAC, Toke‐Bjolgerud E, Edwards A, Vikraman A, Michalsky C, Fossler M, Lemm N et al. ( 2022 ) . The effect of TRV027 on coagulation in COVID‐19: A pilot randomized, placebo‐controlled trial . British Journal of Clinical Pharmacology vol. 89 , ( 4 ) 1495 - 1501 .

Kulkarni S, Glover M, Kapil V, Abrams SML, Partridge S, McCormack T, Sever P, Delles C et al. ( 2022 ) . Management of hypertensive crisis: British and Irish Hypertension Society Position document . Journal of Human Hypertension vol. 37 , ( 10 ) 863 - 879 .

Kapil V, Collett G, Godec T, Gupta J, Maniero C, Ng SM, McIntosh I, Kumar A et al. ( 2022 ) . Longitudinal comparisons of mental health, burnout and well-being in patient-facing, non-patient-facing healthcare professionals and non-healthcare professionals during the COVID-19 pandemic: findings from the CoPE-HCP study . BJPsych Open vol. 8 , ( 5 )

Doykov I, Baldwin T, Spiewak J, Gilmour KC, Gibbons JM, Pade C, Reynolds CJ, McKnight Á et al. ( 2022 ) . Quantitative, multiplexed, targeted proteomics for ascertaining variant specific SARS-CoV-2 antibody response . Cell Reports Methods vol. 2 , ( 9 )

Maniero C, Lopuszko A, Papalois K-B, Gupta A, Kapil V, Khanji MY ( 2022 ) . Non-pharmacological factors for hypertension management: a systematic review of international guidelines . European Journal of Preventive Cardiology vol. 30 , ( 1 ) 17 - 33 .

Reynolds CJ, Pade C, Gibbons JM, Otter AD, Lin K-M, Muñoz Sandoval D, Pieper FP, Butler DK et al. ( 2022 ) . Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure . Science vol. 377 , ( 6603 )

Abani O, Abbas A, Abbas F, Abbas J, Abbas K, Abbas M, Abbasi S, Abbass H et al. ( 2022 ) . Baricitinib in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial and updated meta-analysis . The Lancet vol. 400 , ( 10349 ) 359 - 368 .

Adeyeye E, Kapil V, Lobo MD ( 2022 ) . Hypertension . Medicine vol. 50 , ( J Clin Hypertens (Greenwich) 18 2016 ) 399 - 407 .

Shabbir A, Rathod K, Primus C, Lau C, Chhetri I, Ono M, Khambata R, Massimo G et al. ( 2022 ) . BS37 Leukocytic nitrate reductase activity mitigates systemic inflammation-induced endothelial dysfunction in humans by accelerating resolution . Conference: Basic sciencea167.1 - a1a167 .

Siddiqui I, Gupta J, McIntosh I, Komodromos C, Godec T, Collett G, Ng S, Maniero C et al. ( 2022 ) . The Relationship Between Availability and Changes to Perceived Workplace Support and Their Impact on the Mental Health, Well-being and Burn-Out of Healthcare Professionals (HCP): Insight and Mitigating Strategies From the CoPE-HCP Cohort Study .

Ng SM, Pan J, Mouyis K, Seshasai SRK, Kapil V, Rice KM, Gupta AK ( 2022 ) . Quantifying the Excess Risk of Adverse COVID-19 Outcomes in Unvaccinated Individuals With Diabetes Mellitus, Hypertension, Ischaemic Heart Disease or Myocardial Injury: A Meta-Analysis . Frontiers in Cardiovascular Medicine vol. 9 ,

Astbury S, Reynolds CJ, Butler DK, Muñoz‐Sandoval DC, Lin K, Pieper FP, Otter A, Kouraki A et al. ( 2022 ) . HLA‐DR polymorphism in SARS‐CoV‐2 infection and susceptibility to symptomatic COVID‐19 . Immunology vol. 166 , ( 1 ) 68 - 77 .

Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N et al. ( 2022 ) . Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet vol. 399 , ( 10325 ) 665 - 676 .

Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N et al. ( 2021 ) . Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet vol. 399 , ( 10320 ) 143 - 151 .

Swadling L, Diniz MO, Schmidt NM, Amin OE, Chandran A, Shaw E, Pade C, Gibbons JM et al. ( 2021 ) . Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2 . Nature

Group RC ( 2021 ) . Colchicine in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet Respiratory Medicine vol. 9 , ( 12 ) 1419 - 1426 .

Primus C, Masucci M, Whitear C, Moreira SAM, Kumar NA, Chhetri I, Rathod KS, Khambata R et al. ( 2021 ) . A pro-resolving phenotype underpins the anti-inflammatory effects of inorganic nitrate . European Heart Journal vol. 42 , ( Supplement_1 )

Lau C, Shabbir A, Rathod KS, Chhetri I, Ono M, Hamers AJP, Amarin JJ, Ibrahim A et al. ( 2021 ) . Inorganic nitrate attenuates endothelial dysfunction consequent to systemic inflammation . European Heart Journal vol. 42 , ( Supplement_1 )

Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V et al. ( 2021 ) . Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers . European Heart Journal vol. 42 , ( Supplement_1 )

Gee LC, Massimo G, Lau C, Primus C, Fernandes D, Chen J, Rathod KS, Hamers AJP et al. ( 2021 ) . Inorganic nitrate attenuates cardiac dysfunction: roles for xanthine oxidoreductase and nitric oxide . British Journal of Pharmacology vol. 179 , ( 20 ) 4757 - 4777 .

Gupta RK, Rosenheim J, Bell LC, Chandran A, Guerra-Assuncao JA, Pollara G, Whelan M, Artico J et al. ( 2021 ) . Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study . Lancet Microbe vol. 2 , ( 10 ) e508 - e517 .

Taylor RR, Trivedi B, Patel N, Singh R, Ricketts WM, Elliott K, Yarwood M, White V et al. ( 2021 ) . Post-COVID symptoms reported at asynchronous virtual review and stratified follow-up after COVID-19 pneumonia . Clinical Medicine, Journal of the Royal College of Physicians of London vol. 21 , ( 4 )

Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N et al. ( 2021 ) . Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial . The Lancet vol. 397 , ( 10289 ) 2049 - 2059 .

Zenner D ( 2021 ) . The Barts Health NHS Trust COVID-19 cohort: characteristics, outcomes and risk scoring of patients in East London . International Journal of Tuberculosis and Lung Disease

Reynolds CJ, Pade C, Gibbons JM, Butler DK, Otter AD, Menacho K, Fontana M, Smit A et al. ( 2021 ) . Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose . Science vol. 372 , ( 6549 ) 1418 - 1423 .

Abani O, Abbas A, Abbas F, Abbas M, Abbasi S, Abbass H, Abbott A, Abdallah N et al. ( 2021 ) . Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial . The Lancet vol. 397 , ( 10285 ) 1637 - 1645 .

Harvey G, Godec T, Kapil V, Mackay J, Whitehouse A, Poulter N, Sever PS, Gupta A ( 2021 ) . COMPARING THE DISCRIMINATIVE ABILITY OF DIFFERENT ELECTROGRAPHIC CRITERIA FOR LEFT VENTRICULAR HYPERTROPHY IN PREDICTING CARDIOVASCULAR EVENTS IN HYPERTENSIVE PATIENTS . Journal of Hypertension . vol. 39 , e165 - e166 .

Bakkum MJ, Richir MC, Papaioannidou P, Likic R, Sanz EJ, Christiaens T, Costa JN, Mačiulaitis R et al. ( 2021 ) . EurOP2E – the European Open Platform for Prescribing Education, a consensus study among clinical pharmacology and therapeutics teachers . European Journal of Clinical Pharmacology vol. 77 , ( 8 ) 1209 - 1218 .

Khanji MY, Maniero C, Sher NG, Siddiqui I, Gupta J, Crosby L, Antoniou S, Khan R et al. ( 2021 ) . Early and Mid-Term Implications of the COVID-19 Pandemic on the Physical, Behavioral and Mental Health of Healthcare Professionals: The CoPE-HCP Study Protocol . Frontiers in Psychology vol. 12 , 616280 - 616280 .

Maniero C, Julu P, Shah M, Wolff C, Kapil V, Rull G, Gupta A, Saxena M et al. ( 2021 ) . Dysregulation of central respiratory modulation of cardiac vagal tone is a novel, early sign of dysautonomia in patients with α-synucleinopathies . JOURNAL OF HUMAN HYPERTENSION . vol. 35 , 16 - 16 .

Shabbir A, Lau C, Rathod KS, Chhetri I, Haque A, Godec T, Khambata RS, Kapil V et al. ( 2021 ) . Inorganic nitrate attenuates the systemic inflammatory response in typhoid vaccine-induced endothelial dysfunction in healthy volunteers . EUROPEAN HEART JOURNAL . vol. 42 , 3009 - 3009 .

Reynolds CJ, Swadling L, Gibbons JM, Pade C, Jensen MP, Diniz MO, Schmidt NM, Butler DK et al. ( 2020 ) . Discordant neutralizing antibody and T cell responses in asymptomatic and mild SARS-CoV-2 infection . Science Immunology vol. 5 , ( 54 )

Chung R, Tyebally S, Chen D, Kapil V, Walker JM, Addison D, Ismail-Khan R, Guha A et al. ( 2020 ) . Hypertensive Cardiotoxicity in Cancer Treatment—Systematic Analysis of Adjunct, Conventional Chemotherapy, and Novel Therapies—Epidemiology, Incidence, and Pathophysiology . Journal of Clinical Medicine vol. 9 , ( 10 )

Augusto JB, Menacho K, Andiapen M, Bowles R, Burton M, Welch S, Bhuva AN, Seraphim A et al. ( 2020 ) . Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19 . Wellcome Open Research vol. 5 , 179 - 179 .

Bakkum MJ, Tichelaar J, Papaioannidou P, Likic R, Alvarez EJS, Christiaens T, Costa JN, Mačiulaitis R et al. ( 2020 ) . Harmonizing and improving European education in prescribing: An overview of digital educational resources used in clinical pharmacology and therapeutics . British Journal of Clinical Pharmacology vol. 87 , ( 3 ) 1001 - 1011 .

Kapil V, Khambata RS, Jones DA, Rathod K, Primus C, Massimo G, Fukuto JM, Ahluwalia A ( 2020 ) . The Noncanonical Pathway for In Vivo Nitric Oxide Generation: The Nitrate-Nitrite-Nitric Oxide Pathway . Pharmacological reviews vol. 72 , ( 3 ) 692 - 766 .

Gupta AK, Jneid H, Addison D, Ardehali H, Boehme AK, Borgaonkar S, Boulestreau R, Clerkin K et al. ( 2020 ) . Current perspectives on Coronavirus 2019 (COVID-19) and cardiovascular disease: A white paper by the JAHA editors . J Am Heart Assoce017013 - e017013 .

Lawson AJ, Hameed MA, Brown R, Cappuccio FP, George S, Hinton T, Kapil V, Lenart J et al. ( 2020 ) . Nonadherence to antihypertensive medications is related to pill burden in apparent treatment-resistant hypertensive individuals . Journal of Hypertension

Kapil V, Gupta AK ( 2020 ) . Solar UV Radiation: A Potential Modifiable Risk Factor for Hypertension . Journal of the American Heart Association vol. 9 , ( 5 ) e015627 - e015627 .

Lau CWZ, Hamers AJP, Rathod KS, Shabbir A, Cooper J, Primus CP, Davies C, Mathur A et al. ( 2020 ) . Randomised, double-blind, placebo-controlled clinical trial investigating the effects of inorganic nitrate in hypertension-induced target organ damage: Protocol of the NITRATE-TOD study in the UK . BMJ Open vol. 10 , ( 1 )

Harvey G, Godec T, Kapil V, Mackay J, Whitehouse A, Poulter N, Sever PS, Gupta A ( 2020 ) . Comparing the discriminative ability of electrocardiographic criteria for left ventricular hypertrophy in predicting cardiovascular events in hypertensive patients: post-hoc analysis from the Anglo-Scandinavian cardiovascular outcome trial . JOURNAL OF HUMAN HYPERTENSION . vol. 34 ,

Lobo MD, Sharp ASP, Kapil V, Davies J, de Belder MA, Cleveland T, Bent C, Chapman N et al. ( 2019 ) . Joint UK societies’ 2019 consensus statement on renal denervation . Heart vol. 105 , ( 19 )

Elechi F, Antoniou S, Kapil V ( 2019 ) . 119 Appropriateness of prescribing of direct oral anticoagulants in a university teaching hospital network . Heart . Conference: Stable IHD/Prevention/Hypertension/Lipids vol. 105 ,

Bhagani S, Kapil V, Lobo MD ( 2018 ) . Hypertension . Medicine vol. 46 , ( N Engl J Med 358 2008 ) 509 - 515 .

Kapil V, Rathod KS, Khambata RS, Bahra M, Velmurugan S, Purba A, Watson DS, Barnes MR et al. ( 2018 ) . Sex differences in the nitrate-nitrite-NO• pathway: Role of oral nitrate-reducing bacteria . Free Radical Biology and Medicine vol. 126 , 113 - 121 .

Saxena M, Shour T, Shah M, Wolff CB, Julu POO, Kapil V, Collier DJ, Ng FL et al. ( 2018 ) . Attenuation of Splanchnic Autotransfusion Following Noninvasive Ultrasound Renal Denervation: A Novel Marker of Procedural Success . J Am Heart Assoc vol. 7 , ( 12 )

Brinkman DJ, Tichelaar J, Mokkink LB, Christiaens T, Likic R, Maciulaitis R, Costa J, Sanz EJ et al. ( 2018 ) . Key Learning Outcomes for Clinical Pharmacology and Therapeutics Education in Europe: A Modified Delphi Study . Clinical Pharmacology & Therapeutics vol. 104 , ( 2 ) 317 - 325 .

Kapil V, Green JL, Le Lait C, Wood DM, Dargan PI ( 2018 ) . Misuse of benzodiazepines and Z-drugs in the UK . The British Journal of Psychiatry vol. 205 , ( 5 ) 407 - 408 .

Kapil V, Sobotka PA, Lobo MD, Schmieder RE ( 2018 ) . Central arteriovenous anastomosis to treat resistant hypertension . Current Opinion in Nephrology and Hypertension vol. 27 , ( 1 ) 8 - 15 .

Kapil V ( 2017 ) . Abstracts from the 8th International Conference on cGMP Generators, Effectors and Therapeutic Implications : Bamberg, Germany. 23-25 June, 2017 . BMC Pharmacol Toxicol vol. 18 , ( Suppl 1 ) 64 - 64 .

Saxena M, Shour T, Shah M, Wolff C, Collier DJ, Kapil V, Balawon A, Pheby JM et al. ( 2017 ) . [LB.03.06] ATTENUATION OF SPLANCHNIC AUTOTRANSFUSION FOLLOWING NON-INVASIVE ULTRASOUND RENAL DENERVATION . Journal of Hypertension . vol. 35 , e77 - e78 .

Kapil V, Louthan J, Hamedi N, Antoniou S, Lobo M ( 2017 ) . [PP.22.06] TRANSDERMAL CLONIDINE IN DIFFICULT-TO-TREAT HYPERTENSION PATIENTS ATTENDING A SPECIALIST BP CLINIC IN THE UNITED KINGDOM . Journal of Hypertension . vol. 35 ,

Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al. ( 2017 ) . Sex differences in the inflammatory response and inflammation-induced vascular dysfunction . LANCET . Conference: FASEB vol. 389 , 20 - 20 .

Kapil V ( 2017 ) . Nitrite and Nitrate as a Treatment for Hypertension . Nitrite and Nitrate in Human Health and Disease , Springer Nature

Saxena M, Shour T, Shah M, Wolff C, Collier DJ, Kapil V, Balawon A, Pheby JM et al. ( 2017 ) . Attenuation of splanchnic autotransfusion following non-invasive ultrasound renal denervation: a novel marker of procedural success . JOURNAL OF HUMAN HYPERTENSION . vol. 31 , 679 - 680 .

Pontikaki K, Kapil V, Lobo M, Wei L, Antoniou S ( 2017 ) . Factors contributing to antihypertensive medication intolerance (MI-HTN) . INTERNATIONAL JOURNAL OF CLINICAL PHARMACY . vol. 39 , 264 - 264 .

Patel M, Maudhoo A, Shah K, Kapil V, Lobo M, Mukhtar O ( 2017 ) . Fundal examination in patients with hypertension . JOURNAL OF HUMAN HYPERTENSION . vol. 31 , 685 - 685 .

Lawson A, Brown R, Cappuccio FP, George S, Hinton T, Kapil V, Lenart J, Lobo M et al. ( 2017 ) . Non-adherence to Antihypertensive Medications is related to Total Pill Burden . JOURNAL OF HUMAN HYPERTENSION . vol. 31 , 682 - + .

Kapil V, Louthan J, Hamedi N, Alom R, Antoniou S, Lobo M ( 2017 ) . Transdermal clonidine in difficult-to-treat hypertension patients attending a specialist blood pressure (BP) clinic in the United Kingdom . JOURNAL OF HUMAN HYPERTENSION . vol. 31 , 664 - 665 .

Rathod KS, Jones DA, Van-Eijl TJA, Tsang H, Warren H, Hamshere SM, Kapil V, Jain AK et al. ( 2016 ) . Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: protocol of the NITRATE-OCT study . BMJ Open vol. 6 , ( 12 )

AHLUWALIA A ( 2016 ) . Accelerated resolution underlies sex differences in the inflammatory response in human . Journal of Clinical Investigation vol. 127 , ( 1 ) 169 - 182 .

Floyd CN, Adeel MY, Wolff CB, Julu P, Shah M, Collier DJ, Saxena M, Brier T et al. ( 2016 ) . First-in-man treatment of severe blood pressure variability with baroreflex activation therapy . International Journal of Cardiology vol. 220 , Article C , 577 - 579 .

Lobo MD, Adeel MY, Wolff CB, Julu PO, Shah M, Collier DM, Saxena M, Floyd C et al. ( 2016 ) . [OP.8D.02] FIRST IN MAN TREATMENT OF SEVERE BP VARIABILITY WITH BAROREFLEX ACTIVATION THERAPY . J Hypertens vol. 34 Suppl 2 , e105 - e105 .

Wolff C, Julu PO, Collier DJ, Saxena M, Kapil V, Shah M, Eftychiou S, Mills E et al. ( 2016 ) . [PP.38.09] EFFECTS OF MILD DYNAMIC EXERCISE ON CIRCULATORY AND AUTONOMIC FUNCTION IN HEALTHY VOLUNTEERS . Journal of Hypertension . vol. 34 , e351 - e352 .

Lobo MD, Kapil V ( 2016 ) . Central Iliac Arteriovenous Anastomosis for Hypertension . Interventional Therapies for Secondary and Essential Hypertension , Springer Nature

Saxena M, Antoniou S, Hamedi N, Robinson P, Singh H, Mukhtar O, Kapil V, Lobo MD ( 2016 ) . Multiple drug-intolerant hypertension: a case series utilising a novel-treatment algorithm . British Journal of General Practice vol. 66 , ( 645 ) e285 - e287 .

Antoniou S, Saxena M, Hamedi N, de Cates C, Moghul S, Lidder S, Kapil V, Lobo MD ( 2016 ) . Management of Hypertensive Patients With Multiple Drug Intolerances: A Single-Center Experience of a Novel Treatment Algorithm . Journal of Clinical Hypertension vol. 18 , ( 2 ) 129 - 138 .

Wolff CB, Collier DJ, Shah M, Saxena M, Brier TJ, Kapil V, Green D, Lobo M ( 2016 ) . A Discussion on the Regulation of Blood Flow and Pressure . vol. 876 , 129 - 135 .

Antoniou S, Saxena M, Hamedi N, de Cates C, Moghul S, Lidder S, Kapil V, Lobo MD ( 2016 ) . Management of Hypertensive Patients With Multiple Drug Intolerances: A Single-Center Experience of a Novel Treatment Algorithm . JOURNAL OF CLINICAL HYPERTENSION vol. 18 , ( 2 ) 129 - 138 .

Kapil V, Sobotka PA, Saxena M, Mathur A, Knight C, Dolan E, Stanton A, Lobo MD ( 2015 ) . Central Iliac Arteriovenous Anastomosis for Hypertension: Targeting Mechanical Aspects of the Circulation . Current Hypertension Reports vol. 17 , ( 9 )

Antoniou S, Saxena M, Hamedi N, De Cates C, Moghul S, Lidder S, Lobo M, Kapil V ( 2015 ) . PP.21.35 . Journal of Hypertension . vol. 33 ,

Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2015 ) . Erratum: Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex (Free Radical Biology and Medicine (2013) 65 (1521-1532)) . Free Radical Biology and Medicine vol. 84 ,

Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2015 ) . Erratum to “Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex” [Free Radic. Biol. Med. 65 (2013) 1521–1532] . Free Radical Biology and Medicine vol. 84 ,

Antoniou S, Hamedi N, Lidder S, Saxena M, Brier T, Robinson P, Kapil V, Lobo M ( 2015 ) . CP-081 Management of uncontrolled blood pressure in patients with multiple drug intolerance referred to a specialist hypertension clinic . European Journal of Hospital Pharmacy vol. 22 , ( Suppl 1 )

Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A ( 2015 ) . Dietary nitrate provides sustained blood pressure lowering in hypertensive patients: A randomized, phase 2, double-blind, placebo-controlled study . Hypertension vol. 65 , ( 2 ) 320 - 327 .

Lobo MD, de Belder MA, Cleveland T, Collier D, Dasgupta I, Deanfield J, Kapil V, Knight C et al. ( 2014 ) . Joint UK societies’ 2014 consensus statement on renal denervation for resistant hypertension . Heart vol. 101 , ( 1 )

Kapil V, Khambata RS, Robertson A, Caulfield MJ, Ahluwalia A ( 2014 ) . Dietary Nitrate Provides Sustained Blood Pressure Lowering in Hypertensive Patients . Hypertension vol. 65 , ( 2 ) 320 - 327 .

Kapil V, Lobo MD ( 2014 ) . Hypertension . Medicine vol. 42 , ( 9 ) 485 - 490 .

Scourfield A, Dubrey S, Kapil V ( 2014 ) . Book Reviews . British Journal of Hospital Medicine vol. 75 , ( 8 ) 477 - 477 .

Kapil V, Green JL, Le Lait M, Wood DM, Dargan PI ( 2014 ) . Letter to the Editors . British Journal of Clinical Pharmacology vol. 78 , ( 1 ) 190 - 191 .

Kapil V, Weitzberg E, Lundberg JO, Ahluwalia A ( 2014 ) . Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health . Nitric Oxide - Biology and Chemistry vol. 38 , ( 1 ) 45 - 57 .

Kapil V, Weitzberg E, Lundberg JO, Ahluwalia A ( 2014 ) . Clinical evidence demonstrating the utility of inorganic nitrate in cardiovascular health . Nitric Oxide vol. 38 , 45 - 57 .

Saxena M, Antoniou S, Hamedi N, Chowdhury R, Lidder S, Brier T, Robinson P, Kapil V et al. ( 2014 ) . Anti-hypertensive medicine intolerance - an overlooked and important cause of failed compliance . JOURNAL OF HUMAN HYPERTENSION vol. 28 , ( 10 ) 633 - 633 .

Antoniou S, Hamedi N, Choudhury R, Lidder S, Saxena M, Brier T, Robinson P, Kapil V et al. ( 2014 ) . Management of uncontrolled blood pressure in patients referred to a specialist hypertension clinic with multiple medicines intolerance . JOURNAL OF HUMAN HYPERTENSION vol. 28 , ( 10 ) 645 - 645 .

Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2013 ) . Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex . Free Radical Biology and Medicine vol. 65 , 1521 - 1532 .

Ghosh SM, Kapil V, Fuentes-Calvo I, Bubb KJ, Pearl V, Milsom AB, Khambata R, Maleki-Toyserkani S et al. ( 2013 ) . Enhanced Vasodilator Activity of Nitrite in Hypertension . Hypertension vol. 61 , ( 5 ) 1091 - 1102 .

Ghosh SM, Kapil V, Bubb K, Fuentes-Calvo I, Ahluwalia A ( 2013 ) . P28 Mechanisms underlying nitrite reduction in hypertension: Role for erythrocytic xanthine oxidoreductase . Nitric Oxide . vol. 31 , s24 - s25 .

Velmurugan S, Kapil V, Ghosh SM, Davies S, McKnight A, Aboud Z, Khambata RS, Webb AJ et al. ( 2013 ) . Antiplatelet effects of dietary nitrate in healthy volunteers: Involvement of cGMP and influence of sex . Free Radical Biology and Medicine vol. 65 , 1521 - 1532 .

Huang C, Ng F, Kapil V, Caulfield M, Lobo M ( 2013 ) . Prognostic significance of short term blood pressure variability in a tertiary referral centre population . JOURNAL OF HUMAN HYPERTENSION vol. 27 , ( 10 ) 651 - 651 .

Kapil V, Haydar SMA, Pearl V, Lundberg JO, Weitzberg E, Ahluwalia A ( 2012 ) . Physiological role for nitrate-reducing oral bacteria in blood pressure control . Free Radical Biology and Medicine vol. 55 , 93 - 100 .

Velmurugan S, Pearl V, Davies S, Bahra M, Ghosh S, Kapil V, Ahluwalia A ( 2012 ) . Inorganic nitrate supplementation attenuates platelet reactivity in healthy male volunteers . Nitric Oxide . vol. 27 , s27 - s28 .

Ghosh S, Kapil V, Bubb K, Fuentes I, Ahluwalia A ( 2012 ) . Mechanisms underlying nitrite reduction in hypertension: Role for erythrocyte xanthine oxidoreductase . Nitric Oxide . vol. 27 , s30 - s31 .

Bahra M, Kapil V, Pearl V, Ghosh S, Ahluwalia A ( 2012 ) . Inorganic nitrate ingestion improves vascular compliance but does not alter flow-mediated dilatation in healthy volunteers . Nitric Oxide vol. 26 , ( 4 ) 197 - 202 .

Velmurugan S, Pearl V, Ghosh SM, Davies S, Khambata RS, van Eijl S, Kapil V, Ahluwalia A ( 2012 ) . Inorganic Nitrate Attenuates Platelet Reactivity in Healthy Males but not Females: Role of the Erythrocyte and Cyclic GMP . CIRCULATION vol. 126 , ( 21 )

Bahra M, Kapil V, Pearl V, Ghosh S, Ahluwalia A ( 2012 ) . Inorganic nitrate ingestion decreases blood pressure and improves vascular compliance in healthy volunteers . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 73 , 1004 - 1005 .

Velmurugan S, Kapil V, McKnight AHO, Aboud Z, Davies S, Milsom AB, Pearl V, Liverani E et al. ( 2011 ) . Dietary nitrate attenuates platelet reactivity: Role of the erythrocyte and influence of sex . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 24 , S35 - S36 .

Kapil V, Syed M, Pearl V, Allaker R, Ahluwalia A ( 2011 ) . Interruption of the entero-salivary metabolism of nitrate to nitrite increases blood pressure in healthy volunteers . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 24 , S35 - S35 .

Kapil V, Benjamin N, Hobbs A, Ahluwalia A ( 2011 ) . Response to Inorganic Nitrate for Blood Pressure Lowering? . HYPERTENSION vol. 57 , ( 2 ) E3 - E3 .

Kapil V, Jain AK, Lobo MD ( 2011 ) . Renal Sympathetic Denervation - A Review of Applications in Current Practice . Interventional Cardiology Reviews Research Resources vol. 9 , ( 1 ) 54 - 61 .

Kapil V, Webb AJ, Ahluwalia A ( 2010 ) . Inorganic nitrate and the cardiovascular system . Heart vol. 96 , ( 21 ) 1703 - 1709 .

Kapil V, Milsom AB, Okorie M, Maleki-Toyserkani S, Akram F, Rehman F, Arghandawi S, Pearl V et al. ( 2010 ) . Inorganic nitrate supplementation lowers blood pressure in humans: role for nitrite-derived NO . Hypertension vol. 56 , ( 2 ) 274 - 281 .

Kapil V, Maleki-Toyserkani S, Rehman F, Arghandawi S, Pearl V, Milsom A, Benjamin N, Hobbs A et al. ( 2010 ) . Oral inorganic nitrate lowers blood pressure in healthy male, but not female, volunteers, via bioconversion to nitrite . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 70 , 285 - 285 .

Kapil V, Rehman F, Arghandawi S, Milsom A, Benjamin N, Hobbs A, MacAllister R, Webb A et al. ( 2009 ) . BLOOD PRESSURE LOWERING EFFECTS OF ORAL INORGANIC NITRATE VIA BIOCONVERSION TO NITRITE . BASIC CLIN PHARMACOL vol. 105 , 31 - 31 .

Kapil V, Okorie M, Akram F, Rehman F, Milsom A, Arghandawi S, Pearl V, Deanfield J et al. ( 2009 ) . Oral inorganic nitrate lowers blood pressure and protects against endothelial ischaemia-reperfusion injury in humans . NITRIC OXIDE-BIOLOGY AND CHEMISTRY . vol. 20 , S37 - S37 .

Kapil V, Rull G, Wadley J, Lobo M ( 2009 ) . Severe uncontrolled hypertension treated with microvascular decompression of the brainstem . EUROPEAN HEART JOURNAL . vol. 30 , 439 - 439 .