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Research

Publications: Miss Emanuela Gadaleta

Sivapalan L, Thorn G, Gadaleta E, Kocher H, Ross-Adams H, Chelala C ( 2021 ) . Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer .
Marzec J, Ross-Adams H, Pirrò S, Wang J, Zhu Y, Mao X, Gadaleta E, Ahmad AS et al. ( 2021 ) . The transcriptomic landscape of prostate cancer development and progression: An integrative analysis . Cancers vol. 13 , ( 2 ) 1 - 24 .
Gadaleta E, Fourgoux P, Pirró S, Thorn GJ, Nelan R, Ironside A, Rajeeve V, Cutillas PR et al. ( 2020 ) . Characterization of four subtypes in morphologically normal tissue excised proximal and distal to breast cancer . npj Breast Cancer vol. 6 , ( 1 )
Oscanoa J, Sivapalan L, Gadaleta E, Dayem Ullah AZ, Lemoine NR, Chelala C ( 2020 ) . SNPnexus: A web server for functional annotation of human genome sequence variation (2020 update) . Nucleic Acids Research vol. 48 , ( W1 ) W185 - W192 .
Pirrò S, Spada F, Gadaleta E, Ferrentino F, Thorn GJ, Cesareni G, Chelala C ( 2019 ) . HiPPO and PANDA: Two Bioinformatics Tools to Support Analysis of Mass Cytometry Data . J Comput Biol
Pirrò S, Gadaleta E, Galgani A, Colizzi V, Chelala C ( 2019 ) . SMAC, a computational system to link literature, biomedical and expression data . Scientific Reports vol. 9 , ( 1 )
Barry S, Carlsen E, Marques P, Stiles CE, Gadaleta E, Berney DM, Roncaroli F, Chelala C et al. ( 2019 ) . Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors . Oncogene vol. 38 , ( 27 ) 5381 - 5395 .
Allen N, Allen M, Ahmed K, Gomm J, Nelan R, Nagano A, Chelala C, Gadaleta E et al. ( 2019 ) . Defining molecular signatures to personalise management of patients with early breast cancer . CANCER RESEARCH . Conference: 2018 San Antonio Breast Cancer Symposium from: 04/12/2019 to: 08/12/2019 , vol. 79 ,
Arnandis T, Monteiro P, Adams SD, Bridgeman VL, Rajeeve V, Gadaleta E, Marzec J, Chelala C et al. ( 2018 ) . Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion . Developmental Cell vol. 47 , ( 4 ) 409 - 424.e9 .
Poirot M, Noguer E, Dalenc F, Soules R, Barrett L, Rives A, Kim H-Y, Sjödin B et al. ( 2018 ) . Abstract 5238: Characterization of the enzyme generating the cholesterol metabolite and tumor suppressor dendrogenin A in the breast and its deregulations in breast cancer . Cancer Research . vol. 78 , 5238 - 5238 .
Foxler DE, Bridge KS, Foster JG, Grevitt P, Curry S, Shah KM, Davidson KM, Nagano A et al. ( 2018 ) . A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia . EMBO Mol Med
Fearon AE, Carter EP, Clayton NS, Wilkes EH, Baker AM, Kapitonova E, Bakhouche BA, Tanner Y et al. ( 2018 ) . PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer . Cell Reports vol. 22 , ( 9 ) 2469 - 2481 .
Gadaleta E, Pirrò S, Dayem Ullah AZ, Marzec J, Chelala C ( 2018 ) . BCNTB bioinformatics: The next evolutionary step in the bioinformatics of breast cancer tissue banking . Nucleic Acids Research vol. 46 , ( D1 ) D1055 - D1061 .
Barry S, Solomou A, Vignola L, Collier D, Carlsen E, Gadaleta E, Berney DM, Chelala C et al. ( 2017 ) . A comprehensive analysis of the AIP mutation positive pituitary tumour microenvironment: role of stromal cells and the pro-inflammatory cytokine network . Endocrine Abstracts
Marzec J, Dayem Ullah AZ, Pirrò S, Gadaleta E, Crnogorac-Jurcevic T, Lemoine NR, Kocher HM, Chelala C ( 2017 ) . The Pancreatic Expression Database: 2018 update . Nucleic Acids Res vol. 46 , ( D1 ) D1107 - D1110 .
Sangaralingam A, Dayem Ullah AZ, Marzec J, Gadaleta E, Nagano A, Ross-Adams H, Wang J, Lemoine NR et al. ( 2017 ) . 'Multi-omic' data analysis using O-miner . Brief Bioinform
Makoukji J, Makhoul NJ, Khalil M, El-Sitt S, Aldin ES, Jabbour M, Boulos F, Gadaleta E et al. ( 2016 ) . Gene expression profiling of breast cancer in Lebanese women . Scientific Reports vol. 6 , 36639 - 36639 .
Shaid M, Barry S, Gadaleta E, Chelala C, Korbonits M ( 2016 ) . The clinical, pathological and molecular differences between sparsely and densely granulated somatotroph adenomas . Endocrine Abstracts
Barry S, Carlsen E, Gadaleta E, Berney D, Chelala C, Crnogorac-Jurcevic T, Korbonits M ( 2016 ) . The role of the microenvironment in the invasive phenotype of familial pituitary tumours . Endocrine Abstracts
Stiles C, Barry S, Gadaleta E, Chelala C, Shoulders CC, Korbonits M ( 2015 ) . Investigation of the invasive phenotype of AIP-mutated pituitary adenomas . Endocrine Abstracts
Barry S, Carlsen E, Saleh JA, Gadaleta E, Chelala C, Korbonits M ( 2015 ) . Potential molecular mechanism of AIP-mediated cellular invasion . Endocrine Abstracts
Cutts RJ, Guerra-Assunção JA, Gadaleta E, Ullah AZD, Chelala C ( 2015 ) . BCCTBbp: The Breast Cancer Campaign Tissue Bank bioinformatics portal . Nucleic Acids Research vol. 43 , ( D1 ) D831 - D836 .
Smedley D, Haider S, Durinck S, Pandini L, Provero P, Allen J, Arnaiz O, Awedh MH et al. ( 2015 ) . The BioMart community portal: An innovative alternative to large, centralized data repositories . Nucleic Acids Research vol. 43 , ( W1 ) W589 - W598 .
Dayem Ullah AZ, Cutts RJ, Ghetia M, Gadaleta E, Hahn SA, Crnogorac-Jurcevic T, Lemoine NR, Chelala C ( 2014 ) . The pancreatic expression database: Recent extensions and updates . Nucleic Acids Research vol. 42 , ( D1 )
Gadaleta E, Cutts RJ, Sangaralingam A, Lemoine NR, Chelala C ( 2013 ) . An Integrated Systems Approach to the Study of Pancreatic Cancer . Systems Biology in Cancer Research and Drug Discovery ,
Barry S, Gadaleta E, Chelala C, Korbonits M ( 2013 ) . Gene expression profiling of familial and sporadic pituitary adenomas . Endocrine Abstracts
Barry S, Gadaleta E, Chelala C, Korbonits M ( 2013 ) . Invasion signature' revealed by the analysis of AIP positive and AIP mutation negative human pituitary adenomas . Endocrine Abstracts1 - 1 .
Cutts RJ, Dayem Ullah AZ, Sangaralingam A, Gadaleta E, Lemoine NR, Chelala C ( 2012 ) . O-miner: An integrative platform for automated analysis and mining of-omics data . Nucleic Acids Research vol. 40 , ( W1 )
Guberman JM, Ai J, Arnaiz O, Baran J, Blake A, Baldock R, Chelala C, Croft D et al. ( 2011 ) . BioMart Central Portal: An open database network for the biological community . Database vol. 2011 ,
Cutts RJ, Gadaleta E, Lemoine NR, Chelala C ( 2011 ) . Using BioMart as a framework to manage and query pancreatic cancer data . Database vol. 2011 ,
Gadaleta E, Cutts RJ, Kelly GP, Crnogorac-Jurcevic T, Kocher HM, Lemoine NR, Chelala C ( 2011 ) . A global insight into a cancer transcriptional space using pancreatic data: Importance, findings and flaws . Nucleic Acids Research vol. 39 , ( 18 ) 7900 - 7907 .
Petkov B, Vitale V, Tomasi C, Gadaleta E, Mazzola M, Lanconelli C, Lupi A, Busetto M et al. ( 2011 ) . Preliminary assessment of the risks associated with solar ultraviolet-A exposure . Radiat Environ Biophys vol. 50 , ( 1 ) 219 - 229 .
Gadaleta E, Lemoine NR, Chelala C ( 2011 ) . Online resources of cancer data: barriers, benefits and lessons . Brief Bioinform vol. 12 , ( 1 ) 52 - 63 .
Cutts RJ, Gadaleta E, Hahn SA, Crnogorac-Jurcevic T, Lemoine NR, Chelala C ( 2011 ) . The pancreatic expression database: 2011 update . Nucleic Acids Research vol. 39 , ( SUPPL. 1 )