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Research

Publications: Dr Sayka Barry

Garcia-Rendueles AR, Chenlo M, Oroz-Gonjar F, Solomou A, Mistry A, Barry S, Gaston-Massuet C, Garcia-Lavandeira M et al. ( 2021 ) . RET signalling provides tumorigenic mechanism and tissue specificity for AIP-related somatotrophinomas . Oncogene vol. 40 , ( 45 ) 6354 - 6368 .
Marques P, Barry S, Carlsen E, Collier D, Ronaldson A, Dorward N, Grieve J, Mendoza N et al. ( 2020 ) . The role of the tumour microenvironment in the angiogenesis of pituitary tumours . Endocrine
Barry S, Carlsen E, Marques P, Stiles CE, Gadaleta E, Berney DM, Roncaroli F, Chelala C et al. ( 2019 ) . Tumor microenvironment defines the invasive phenotype of AIP-mutation-positive pituitary tumors . Oncogene vol. 38 , ( 27 ) 5381 - 5395 .
Sun D, Stopka-Farooqui U, Barry S, Aksoy E, Parsonage G, Vossenkämper A, Capasso M, Wan X et al. ( 2019 ) . Aryl Hydrocarbon Receptor Interacting Protein Maintains Germinal Center B Cells through Suppression of BCL6 Degradation . Cell Reports vol. 27 , ( 5 ) 1461 - 1471.e4 .
Marques P, Barry S, Carlsen E, Collier D, Ronaldson A, Awad S, Dorward N, Grieve J et al. ( 2019 ) . Pituitary tumour fibroblast-derived cytokines influence tumour aggressiveness . Endocrine-Related Cancer vol. 26 , ( 12 ) 853 - 865 .
Marques P, Barry S, Ronaldson A, Ogilvie A, Storr HL, Goadsby PJ, Powell M, Dang MN et al. ( 2018 ) . Emergence of Pituitary Adenoma in a Child during Surveillance: Clinical Challenges and the Family Members' View in an AIP Mutation-Positive Family . Int J Endocrinol vol. 2018 , 8581626 - 8581626 .
Hernández-Ramírez LC, Morgan RML, Barry S, D'Acquisto F, Prodromou C, Korbonits M ( 2018 ) . Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland . Oncotarget vol. 9 , ( 10 ) 9177 - 9198 .
Radian S, Diekmann Y, Gabrovska P, Holland B, Bradley L, Wallace H, Stals K, Bussell AM et al. ( 2017 ) . Increased Population Risk of AIP-Related Acromegaly and Gigantism in Ireland . Human Mutation vol. 38 , ( 1 ) 78 - 85 .
Rodd C, Millette M, Iacovazzo D, Stiles CE, Barry S, Evanson J, Albrecht S, Caswell R et al. ( 2016 ) . Somatic GPR101 Duplication Causing X-Linked Acrogigantism (XLAG)—Diagnosis and Management . The Journal of Clinical Endocrinology & Metabolism vol. 101 , ( 5 ) 1927 - 1930 .
Dénes J, Kasuki L, Trivellin G, Colli LM, Takiya CM, Stiles CE, Barry S, De Castro M et al. ( 2015 ) . Regulation of aryl hydrocarbon receptor interacting protein (AIP) protein expression by MiR-34a in sporadic somatotropinomas . PLoS ONE vol. 10 , ( 2 )
Butz H, Szabo PM, Igaz P, Czirjak S, Barry S, Liko I, Korbonits M, Racz K et al. ( 2014 ) . Integrative Analysis of Chromosomal, Trancriptome, Proteomic and Mirnome Data Reveals Involvement of Impaired Developmental Processes in Clinically Non-Functional Pituitary Adenoma Formation . ENDOCRINE REVIEWS . vol. 35 ,
Radian S, Gabrovska P, Holland B, Wallace H, Ryan AW, McGurren K, Stals K, Bussell A-M et al. ( 2014 ) . Population Screening for the Irish Founder AIP Mutation R304*Reveals a Prevalence of 1/500 in the Local Population, While High Mutation Frequency Is Present Among Irish Familial and Sporadic Somatotropinoma Patients . ENDOCRINE REVIEWS . vol. 35 ,
Barry S, Chelala C, Lines K, Sunamura M, Wang A, Marelli-Berg FM, Brennan C, Lemoine NR et al. ( 2013 ) . S100P is a metastasis-associated gene that facilitates transendothelial migration of pancreatic cancer cells . Clin Exp Metastasis vol. 30 , ( 3 ) 251 - 264 .
Crnogorac-Jurcevic T, Chelala C, Barry S, Harada T, Bhakta V, Lattimore S, Jurcevic S, Bronner M et al. ( 2013 ) . Molecular analysis of precursor lesions in familial pancreatic cancer . PLoS One vol. 8 , ( 1 )
Tolhurst RS, Thomas RS, Kyle FJ, Patel H, Periyasamy M, Photiou A, Thiruchelvam PTR, Lai C-F et al. ( 2011 ) . Transient over-expression of estrogen receptor-α in breast cancer cells promotes cell survival and estrogen-independent growth . Breast Cancer Res Treat vol. 128 , ( 2 ) 357 - 368 .
Chelala C, Hahn SA, Whiteman HJ, Barry S, Hariharan D, Radon TP, Lemoine NR, Crnogorac-Jurcevic T ( 2007 ) . Pancreatic Expression database: a generic model for the organization, integration and mining of complex cancer datasets . BMC Genomics vol. 8 ,
Whiteman HJ, Weeks ME, Dowen SE, Barry S, Timms JF, Lemoine NR, Crnogorac-Jurcevic T ( 2007 ) . The role of S100P in the invasion of pancreatic cancer cells is mediated through cytoskeletal changes and regulation of cathepsin D . Cancer Res vol. 67 , ( 18 ) 8633 - 8642 .