Publications: Mr Alastair Noyce

Sanyaolu AO, Mohamed W, Makarious MB, August JL, Kekenadze M, Heilbron K, Periñán MT, Noyce A et al. ( 2025 ) . Chapter 4 Mendelian randomization and Parkinson’s disease . Integrative Omics in Parkinson's Disease , Elsevier

Kim JJ, Bandres-Ciga S, Heilbron K, Blauwendraat C, Noyce AJ ( 2024 ) . Bidirectional relationship between olfaction and Parkinson’s disease . npj Parkinson's Disease vol. 10 , ( 1 )

Tan AH, Saffie-Awad P, Schuh AFS, Lim S-Y, Madoev H, Ahmad-Annuar A, Solle J, Wegel CE et al. ( 2024 ) . Global Perspectives on Returning Genetic Research Results in Parkinson Disease . Neurology Genetics vol. 10 , ( 6 )

Brolin KA, Schaeffer E, Kuri A, Rumrich IK, Schuh AFS, Darweesh SKL, Kaasinen V, Tolppanen A et al. ( 2024 ) . Environmental Risk Factors for Parkinson's Disease: A Critical Review and Policy Implications . Movement Disorders

Bramich S, Noyce A, Pérez-Carbonell L, Bindoff A, Wang X, King A, Naismith S, Vickers J et al. ( 2024 ) . P027 Dream characteristics are sex-specific in REM Sleep Behaviour Disorder and healthy older adults . SLEEP Advances vol. 5 , ( Supplement_1 ) a38 - a39 .

Mahlknecht P, Leiter S, Horlings C, Schwarzová K, Egner I, Stockner H, Marini K, Theyer C et al. ( 2024 ) . Preferences regarding Disclosure of Risk for Parkinson's Disease in a Population‐based Study . Movement Disorders Clinical Practice

Azoidou V, Noyce AJ, Simonet C ( 2024 ) . The effect of tactile cueing on dual task performance in Parkinson’s disease. A systematic review and meta-analysis . Clinical Parkinsonism & Related Disorders vol. 11 ,

Step K, Eltaraifee E, Elsayed I, Rasaholiarison N, Okubadejo N, Walker R, Mohamed W, Rizig M et al. ( 2024 ) . Advancing Parkinson's Disease Research in Africa: A Strategic Training Framework of the Global Parkinson's Genetics Program . Movement Disorders

Lim S-Y, Tan AH, Ahmad-Annuar A, Okubadejo NU, Lohmann K, Morris HR, Toh TS, Tay YW et al. ( 2024 ) . Uncovering the genetic basis of Parkinson's disease globally: from discoveries to the clinic . The Lancet Neurology vol. 23 , ( 12 ) 1267 - 1280 .

Schaeffer E, Yilmaz R, St. Louis EK, Noyce AJ ( 2024 ) . Ethical Considerations for Identifying Individuals in the Prodromal/Early Phase of Parkinson’s Disease: A Narrative Review . Journal of Parkinson's Disease vol. 14 , ( s2 ) s307 - s319 .

Pereira GM, Teixeira-dos-Santos D, Soares NM, Marconi GA, Friedrich DC, Saffie Awad P, Santos-Lobato BL, Brandão PRP et al. ( 2024 ) . A systematic review and meta-analysis of the prevalence of Parkinson’s disease in lower to upper-middle-income countries . npj Parkinson's Disease vol. 10 , ( 1 )

Joerres C, Patyjewicz M, Cetin M, Bariana T, Onen B, Hone L, Green J, Tambe D et al. ( 2024 ) . Assessing the prevalence of nitrous oxide usage in patients aged 35 years or under presenting with unprovoked VTE between 2021-2023 . Thrombosis Update vol. 16 ,

Araújo R, Noyce AJ, Bloem BR ( 2024 ) . Therapeutic ancillary examinations in clinical neurology . Journal of Neurology vol. 271 , ( 10 ) 7026 - 7029 .

Lázaro‐Figueroa A, Hernández‐Medrano AJ, Ramírez‐Pineda DB, Cadavid AN, Makarious M, Foo JN, Alvarado CX, Bandres‐Ciga S et al. ( 2024 ) . Is SH3GL2 p.G276V the Causal Functional Variant Underlying Parkinson's Disease Risk at this Locus? . Movement Disorders vol. 39 , ( 11 ) 2117 - 2119 .

Rudd KD, Lawler K, Callisaya ML, Bindoff AD, Chiranakorn-Costa S, Li R, McDonald JS, Salmon K et al. ( 2024 ) . Hand Motor Dysfunction Is Associated with Both Subjective and Objective Cognitive Impairment across the Dementia Continuum . Dementia and Geriatric Cognitive Disorders1 - 11 .

Francis M, Zirra A, Haque T, Gallagher D, Budu C, Lees AJ, Schrag A, Noyce AJ et al. ( 2024 ) . Rapid Voluntary Blinking as a Clinical Marker of Parkinson’s Disease . Journal of Parkinson's Disease vol. 14 , ( 5 ) 993 - 997 .

Zhang Q, Noyce AJ, Robson J, Giovannoni G, Marshall CR, Dobson R ( 2024 ) . No association between oral contraceptive exposure and subsequent MS: A population-based nested case–control study in primary care . Multiple Sclerosis Journal vol. 30 , ( 9 ) 1221 - 1226 .

Zaloum SA, Paris A, Mair D, Gutteridge C, Ayling RM, Onen BL, Walton J, Workman A et al. ( 2024 ) . Evaluation of an ambulatory care pathway for patients with nitrous oxide-induced myeloneuropathy . BMJ Neurology Open vol. 6 , ( 1 )

Li X, Gill A, Panzarasa P, Bestwick J, Schrag A, Noyce A, De Simoni A ( 2024 ) . Web Application to Enable Online Social Interactions in a Parkinson Disease Risk Cohort: Feasibility Study and Social Network Analysis . JMIR Formative Research

Rees RN, Noyce AJ, Schrag AE ( 2024 ) . Identification of Prodromal Parkinson Disease . Neurology vol. 102 , ( 11 )

Patyjewicz M, Mair D, Zaloum SA, Onen B, Walton J, Dobson R, Joerres C, Shah AM et al. ( 2024 ) . Recreational nitrous oxide and thrombotic events: a case series . BMJ Neurology Open vol. 6 , ( 1 )

Badenoch JB, Paris A, Jacobs BM, Noyce AJ, Marshall CR, Waters S ( 2024 ) . Neuroanatomical and prognostic associations of depression in Parkinson’s disease . Journal of Neurology Neurosurgery & Psychiatry vol. 95 , ( 10 )

Chang Y-H, Periñan MT, Wilson M, Noyce AJ ( 2024 ) . AccessPD as a next generation registry to accelerate Parkinson’s disease research . npj Parkinson's Disease vol. 10 , ( 1 )

Simonet C, Pérez‐Carbonell L, Galmés‐Ordinas MA, Huxford BFR, Chohan H, Gill A, Leschziner G, Lees AJ et al. ( 2024 ) . The Motor Dysfunction Seen in Isolated REM Sleep Behavior Disorder . Movement Disorders vol. 39 , ( 6 ) 1054 - 1059 .

Ojo OO, Bandres‐Ciga S, Makarious MB, Crea PW, Hernandez DG, Houlden H, Rizig M, Singleton AB et al. ( 2024 ) . GBA1 rs3115534 Is Associated with REM Sleep Behavior Disorder in Parkinson's Disease in Nigerians . Movement Disorders vol. 39 , ( 4 ) 728 - 733 .

Lucas A, Noyce AJ, Gernez E, Khoury JME, Garcon G, Cavalier E, Antherieu S, Grzych G ( 2024 ) . Nitrous oxide abuse direct measurement for diagnosis and follow-up: update on kinetics and impact on metabolic pathways . Clinical Chemistry and Laboratory Medicine vol. 62 , ( 12 ) 2356 - 2372 .

Reynoso A, Torricelli R, Jacobs BM, Shi J, Aslibekyan S, Norcliffe‐Kaufmann L, Noyce AJ, Heilbron K ( 2024 ) . Gene–Environment Interactions for Parkinson's Disease . Annals of Neurology vol. 95 , ( 4 ) 677 - 687 .

Kim JJ, Vitale D, Otani DV, Lian MM, Heilbron K, Iwaki H, Lake J, Solsberg CW et al. ( 2023 ) . Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease . Nature Genetics vol. 56 , ( 1 ) 27 - 36 .

Gonzalez‐Robles C, Bartlett M, Burnell M, Clarke CS, Haar S, Hu MT, Huxford B, Jha A et al. ( 2023 ) . Embedding Patient Input in Outcome Measures for Long‐Term Disease‐Modifying Parkinson Disease Trials . Movement Disorders vol. 39 , ( 2 ) 433 - 438 .

Gernez E, Lucas A, Niguet J, Bennis A, Diesnis R, Noyce AJ, Grzych G ( 2023 ) . What biological markers could be used for diagnosis and monitoring of nitrous oxide abuse? . European Journal of Neurology vol. 31 , ( 3 )

Bramich S, Noyce AJ, King AE, Naismith SL, Kuruvilla MV, Lewis SJG, Roccati E, Bindoff AD et al. ( 2023 ) . Isolated rapid eye movement sleep behaviour disorder (iRBD) in the Island Study Linking Ageing and Neurodegenerative Disease (ISLAND) Sleep Study: protocol and baseline characteristics . Journal of Sleep Research vol. 33 , ( 3 )

Toffoli M, Chohan H, Mullin S, Jesuthasan A, Yalkic S, Koletsi S, Menozzi E, Rahall S et al. ( 2023 ) . Phenotypic effect of GBA1 variants in individuals with and without Parkinson's disease: The RAPSODI study . Neurobiology of Disease vol. 188 ,

Mair D, Zaloum SA, Patel F, Noyce AJ ( 2023 ) . Effectiveness of interactive workshops to raise awareness of the neurological harms associated with nitrous oxide use: a cross-sectional study . The Lancet vol. 402 ,

Bernard Healey SA, Giovannoni G, Noyce A, Dobson R, Jacobs BM ( 2023 ) . Impact of multiple sclerosis risk alleles on the plasma proteome . Brain vol. 147 , ( 2 ) e17 - e21 .

Paris A, Mair D, Zaloum S, Onen B, Noyce AJ ( 2023 ) . Nitrous oxide and its neurological harms . The Lancet Neurology vol. 22 , ( 10 )

Gonzalez-Robles C, Weil RS, van Wamelen D, Bartlett M, Burnell M, Clarke CS, Hu MT, Huxford B et al. ( 2023 ) . Outcome Measures for Disease-Modifying Trials in Parkinson’s Disease: Consensus Paper by the EJS ACT-PD Multi-Arm Multi-Stage Trial Initiative . Journal of Parkinson's Disease vol. 13 , ( 6 ) 1011 - 1033 .

Jacobs BM, Tank P, Bestwick JP, Noyce AJ, Marshall CR, Mathur R, Giovannoni G, Dobson R ( 2023 ) . Modifiable risk factors for multiple sclerosis have consistent directions of effect across diverse ethnic backgrounds: a nested case–control study in an English population-based cohort . Journal of Neurology vol. 271 , ( 1 ) 241 - 253 .

Wang X, St George RJ, Bindoff AD, Noyce AJ, Lawler K, Roccati E, Bartlett L, Tran SN et al. ( 2023 ) . Estimating presymptomatic episodic memory impairment using simple hand movement tests: A cross‐sectional study of a large sample of older adults . Alzheimer's & Dementia vol. 20 , ( 1 ) 173 - 182 .

Simonet C, Mahlknecht P, Marini K, Seppi K, Gill A, Bestwick JP, Lees AJ, Giovannoni G et al. ( 2023 ) . The Emergence and Progression of Motor Dysfunction in Individuals at Risk of Parkinson's Disease . Movement Disorders vol. 38 , ( 9 ) 1636 - 1644 .

Noyce A ( 2023 ) . Nitrous oxide-induced myeloneuropathy: a case series . Journal of Neurology, Neurosurgery and Psychiatry

Leonard HL, Murtadha R, Martinez-Carrasco A, Jama A, Müller-Nedebock AC, Gil-Martinez A-L, Illarionova A, Moore A et al. ( 2023 ) . Author Correction: The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data . npj Parkinson's Disease vol. 9 , ( 1 )

Jacobs BM, Schalk L, Dunne A, Scalfari A, Nandoskar A, Gran B, Mein CA, Sellers C et al. ( 2023 ) . ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK . BMJ Open vol. 13 , ( 5 )

Senkevich K, Alipour P, Chernyavskaya E, Yu E, Noyce AJ, Gan‐Or Z ( 2023 ) . Potential Protective Link Between Type I Diabetes and Parkinson's Disease Risk and Progression . Movement Disorders vol. 38 , ( 7 ) 1350 - 1355 .

Pérez‐Carbonell L, Simonet C, Chohan H, Gill A, Leschziner G, Schrag A, Noyce AJ ( 2023 ) . The Views of Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder on Risk Disclosure . Movement Disorders vol. 38 , ( 6 ) 1089 - 1093 .

Alvarez Jerez P, Alcantud JL, de los Reyes-Ramírez L, Moore A, Ruz C, Vives Montero F, Rodriguez-Losada N, Saini P et al. ( 2023 ) . Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson’s disease . npj Parkinson's Disease vol. 9 , ( 1 )

Leonard HL, Murtadha R, Martinez-Carrasco A, Jama A, Müller-Nedebock AC, Gil-Martinez A-L, Illarionova A, Moore A et al. ( 2023 ) . The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data . npj Parkinson's Disease vol. 9 , ( 1 )

Foltynie T, Gandhi S, Gonzalez-Robles C, Zeissler M-L, Mills G, Barker R, Carpenter J, Schrag A et al. ( 2023 ) . Towards a multi-arm multi-stage platform trial of disease modifying approaches in Parkinson’s disease . Brain vol. 146 , ( 7 ) 2717 - 2722 .

Paris A, Lake L, Joseph A, Workman A, Walton J, Hayton T, Evangelou N, Lilleker JB et al. ( 2023 ) . Nitrous oxide-induced subacute combined degeneration of the cord: diagnosis and treatment . Practical Neurology vol. 23 , ( 3 ) 222 - 228 .

Nagy AV, Leschziner G, Eriksson SH, Lees A, Noyce AJ, Schrag A ( 2023 ) . Cognitive impairment in REM-sleep behaviour disorder and individuals at risk of Parkinson's disease . Parkinsonism & Related Disorders vol. 109 ,

Frisoni GB, Altomare D, Ribaldi F, Villain N, Brayne C, Mukadam N, Abramowicz M, Barkhof F et al. ( 2023 ) . Dementia prevention in memory clinics: recommendations from the European task force for brain health services . The Lancet Regional Health - Europe vol. 26 ,

Noyce A ( 2022 ) . The association between anti-epileptic drugs and incident Parkinson’s disease in UK Biobank . JAMA Neurology

Bramich S, Verdi K, Salmon K, Noyce A, Alty J ( 2022 ) . REM sleep behaviour disorder: the importance of early identification in primary care . British Journal of General Practice vol. 73 , ( 726 ) 40 - 42 .

Dadu A, Satone V, Kaur R, Hashemi SH, Leonard H, Iwaki H, Makarious MB, Billingsley KJ et al. ( 2022 ) . Identification and prediction of Parkinson’s disease subtypes and progression using machine learning in two cohorts . npj Parkinson's Disease vol. 8 , ( 1 )

Krohn L, Heilbron K, Blauwendraat C, Reynolds RH, Yu E, Senkevich K, Rudakou U, Estiar MA et al. ( 2022 ) . Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects . Nature Communications vol. 13 , ( 1 )

Zirra A, Rao SC, Bestwick J, Rajalingam R, Marras C, Blauwendraat C, Mata IF, Noyce AJ ( 2022 ) . Gender Differences in the Prevalence of Parkinson's Disease . Movement Disorders Clinical Practice vol. 10 , ( 1 ) 86 - 93 .

Periñán MT, Brolin K, Bandres‐Ciga S, Blauwendraat C, Klein C, Gan‐Or Z, Singleton A, Gomez‐Garre P et al. ( 2022 ) . Effect Modification between Genes and Environment and Parkinson's Disease Risk . Annals of Neurology vol. 92 , ( 5 ) 715 - 724 .

Jacobs BM, Peter M, Giovannoni G, Noyce AJ, Morris HR, Dobson R ( 2022 ) . Towards a global view of multiple sclerosis genetics . Nature Reviews Neurology vol. 18 , ( 10 ) 613 - 623 .

Kent DM, Leung LY, Puttock EJ, Wang AY, Luetmer PH, Kallmes DF, Nelson J, Fu S et al. ( 2022 ) . Development of Parkinson Disease and Its Relationship with Incidentally Discovered White Matter Disease and Covert Brain Infarction in a Real‐World Cohort . Annals of Neurology vol. 92 , ( 4 ) 620 - 630 .

Schumacher‐Schuh AF, Bieger A, Okunoye O, Mok KY, Lim S, Bardien S, Ahmad‐Annuar A, Santos‐Lobato BL et al. ( 2022 ) . Underrepresented Populations in Parkinson's Genetics Research: Current Landscape and Future Directions . Movement Disorders vol. 37 , ( 8 ) 1593 - 1604 .

Day JO, Smith S, Noyce AJ, Alty J, Jeffery A, Chapman R, Carroll C ( 2022 ) . Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT . Journal of Parkinson's Disease vol. 12 , ( 5 ) 1605 - 1609 .

Bramich S, King A, Kuruvilla M, Naismith SL, Noyce A, Alty J ( 2022 ) . Isolated REM sleep behaviour disorder: current diagnostic procedures and emerging new technologies . Journal of Neurology vol. 269 , ( 9 ) 4684 - 4695 .

Liu H, Dehestani M, Blauwendraat C, Makarious MB, Leonard H, Kim JJ, Schulte C, Noyce A et al. ( 2022 ) . Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors . Annals of Neurology vol. 92 , ( 2 ) 270 - 278 .

Foote IF, Jacobs BM, Mathlin G, Watson CJ, Bothongo PL, Waters S, Dobson R, Noyce AJ et al. ( 2022 ) . The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study . Neurobiology of Aging vol. 117 , 222 - 235 .

Hone L, Jacobs BM, Marshall C, Giovannoni G, Noyce A, Dobson R ( 2022 ) . Age-specific effects of childhood body mass index on multiple sclerosis risk . Journal of Neurology vol. 269 , ( 9 ) 5052 - 5060 .

Simonet C, Bestwick J, Jitlal M, Waters S, Ben-Joseph A, Marshall CR, Dobson R, Marrium S et al. ( 2022 ) . Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population . JAMA Neurology vol. 79 , ( 4 ) 359 - 369 .

Marshall CR, Noyce AJ, Neligan A, Dobson R ( 2022 ) . Brain health: The hidden casualty of a humanitarian crisis . The Lancet Regional Health - Europe vol. 15 ,

Noyce A ( 2022 ) . No evidence for association between polygenic risk of Multiple Sclerosis and MRI phenotypes in ~30,000 healthy adult UK Biobank participants . Multiple Sclerosis Journal

Noyce A ( 2022 ) . Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population . JAMA Neurology

Cornejo‐Olivas M, Wu L, Noyce A ( 2022 ) . Disruption of Mitochondrial Complex I Induces Progressive Parkinsonism . Movement Disorders vol. 37 , ( 3 ) 478 - 478 .

Bothongo PLK, Jitlal M, Parry E, Waters S, Foote IF, Watson CJ, Cuzick J, Giovannoni G et al. ( 2022 ) . Dementia risk in a diverse population: A single-region nested case-control study in the East End of London . The Lancet Regional Health - Europe vol. 15 ,

Noyce A ( 2022 ) . Surveying global availability of Parkinson’s disease treatment . Journal of Parkinson's Disease

Noyce A ( 2022 ) . The potential utility of smell testing to screen for neurodegenerative disorders . Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare

Dobson R, Marshall C, Noyce A ( 2022 ) . Social determinants of neurological disease: tackling inequalities . The Lancet Neurology vol. 21 , ( 2 ) 122 - 123 .

Noyce A ( 2022 ) . Developing and Assessing a New Web-based Tapping Test for Measuring Distal Movement in Parkinson’s Disease: a Distal Finger Tapping Test . Scientific Reports

Mitchell E, Chohan H, Bestwick JP, Noyce AJ ( 2022 ) . Alcohol and Parkinson’s Disease: A Systematic Review and Meta-Analysis . Journal of Parkinson's Disease vol. 12 , ( 8 ) 2369 - 2381 .

Chohan H, Simonet C, Gill A, Schrag A, Noyce A, Perez-Carbonell L ( 2022 ) . What, when and how should the information on iRBD and risk of Parkinson's disease and related conditions be communicated? . MOVEMENT DISORDERS . vol. 37 , S622 - S622 .

Storm CS, Kia DA, Almramhi MM, Bandres-Ciga S, Finan C, Hingorani AD, Wood NW ( 2021 ) . Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome . Nature Communications vol. 12 , ( 1 )

Bestwick JP, Auger SD, Simonet C, Rees RN, Rack D, Jitlal M, Giovannoni G, Lees AJ et al. ( 2021 ) . Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm . npj Parkinson's Disease vol. 7 , ( 1 )

Huxford B, Haque T, Joseph AB, Simonet C, Gallagher D, Budu C, Dobson R, Noyce A ( 2021 ) . Parkinson's Disease and Type 2 Diabetes: HbA1c Is Associated with Motor and Cognitive Severity . Movement Disorders vol. 37 , ( 2 ) 427 - 428 .

Heilbron K, Jensen MP, Bandres-Ciga S, Fontanillas P, Blauwendraat C, Nalls MA, Singleton AB, Smith GD et al. ( 2021 ) . Unhealthy Behaviours and Risk of Parkinson’s Disease: A Mendelian Randomisation Study . Journal of Parkinson's Disease vol. 11 , ( 4 ) 1981 - 1993 .

Bestwick J, Auger S, Schrag A, Grosset DG, Kanavou S, Giovannoni G, Lees AJ, Cuzick J et al. ( 2021 ) . Optimising classification of Parkinson’s disease based on motor, olfactory, neuropsychiatric and sleep features . npj Parkinson's Disease

Hone L, Jacobs BM, Marshall C, Giovannoni G, Noyce A, Dobson R ( 2021 ) . Age-specific effects of childhood Body Mass Index on multiple sclerosis risk .

Noyce A, Beccano-Kelly D, Bandres-Ciga S, Schumacher Schuh A, Zenebe Y, Siddiqi B ( 2021 ) . Tackling underrepresentation to aid understanding of Parkinson’s disease: Progress and further opportunities . Physiology News ( Autumn 123 )

Simonet C, Noyce AJ ( 2021 ) . Domotics, Smart Homes, and Parkinson’s Disease . Journal of Parkinson's Disease vol. 11 , ( s1 ) s55 - s63 .

Simonet C, Noyce A ( 2021 ) . Mild parkinsonian signs: the interface between aging and Parkinson’s disease . Advances in Clinical Neuroscience & Rehabilitation vol. 20 ,

Gialluisi A, Reccia MG, Modugno N, Nutile T, Lombardi A, Di Giovannantonio LG, Pietracupa S, Ruggiero D et al. ( 2021 ) . Identification of sixteen novel candidate genes for late onset Parkinson’s disease . Molecular Neurodegeneration vol. 16 , ( 1 )

Jacobs BM, Noyce AJ, Bestwick J, Belete D, Giovannoni G, Dobson R ( 2021 ) . Gene-Environment Interactions in Multiple Sclerosis: A UK Biobank Study . Neurology Neuroimmunology & Neuroinflammation vol. 8 , ( 4 )

Blauwendraat C, Iwaki H, Makarious MB, Bandres‐Ciga S, Leonard HL, Grenn FP, Lake J, Krohn L et al. ( 2021 ) . Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease . Annals of Neurology vol. 90 , ( 1 ) 35 - 42 .

Estiar MA, Senkevich K, Yu E, Varghaei P, Krohn L, Bandres‐Ciga S, Noyce AJ, Rouleau GA et al. ( 2021 ) . Lack of Causal Effects or Genetic Correlation between Restless Legs Syndrome and Parkinson's Disease . Movement Disorders vol. 36 , ( 8 ) 1967 - 1972 .

Bandres-Ciga S, Saez-Atienzar S, Kim JJ, Makarious MB, Faghri F, Diez-Fairen M, Iwaki H, Leonard H et al. ( 2021 ) . Correction to: Large‑scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease . Acta Neuropathologica vol. 142 , ( 1 ) 223 - 224 .

Ismail AS, Goodwin GR, Castrejon-Pita JR, Noyce AJ, Azevedo HS ( 2021 ) . A novel capsule-based smell test fabricated via coaxial dripping . Journal of The Royal Society Interface vol. 18 , ( 177 ) Article rsif.2021.0039 ,

Chen Z, Zhang D, Reynolds RH, Gustavsson EK, García-Ruiz S, D’Sa K, Fairbrother-Browne A, Vandrovcova J et al. ( 2021 ) . Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage . Nature Communications vol. 12 , ( 1 )

Bestwick JP, Auger SD, Simonet C, Rees RN, Rack D, Jitlal M, Giovannoni G, Lees AJ et al. ( 2021 ) . Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm . npj Parkinson's Disease vol. 7 , ( 1 )

Jitlal M, Amirthalingam G, Karania T, Parry E, Neligan A, Dobson R, Noyce A, MARSHALL C ( 2021 ) . The influence of socioeconomic deprivation on dementia mortality, age at death and quality of diagnosis: a nationwide death records study in England and Wales 2001-2017 . Journal of Alzheimer's Disease

Chohan H, Senkevich K, Patel RK, Bestwick JP, Jacobs BM, Ciga SB, Gan‐Or Z, Noyce AJ ( 2021 ) . Type 2 Diabetes as a Determinant of Parkinson's Disease Risk and Progression . Movement Disorders vol. 36 , ( 6 ) 1420 - 1429 .

Foote IF, Jacobs BM, Mathlin G, Watson CJ, Bothongo PL, Waters S, Dobson R, Noyce AJ et al. ( 2021 ) . The Genetic Architecture of Alzheimer’s Disease Risk: A Genomic Structural Equation Modelling Study .

Jensen MP, Jacobs BM, Dobson R, Bandres‐Ciga S, Blauwendraat C, Schrag A, Noyce AJ, Consortium TIPDG ( 2021 ) . Lower Lymphocyte Count is Associated With Increased Risk of Parkinson's Disease . Annals of Neurology vol. 89 , ( 4 ) 803 - 812 .

Kang X, Ploner A, Pedersen N, Bandres-Ciga S, Noyce A, Wirdefeldt K, Williams DM ( 2021 ) . Tumor Necrosis Factor Inhibition and Parkinson Disease: A Mendelian Randomization Study . Neurology

Noyce A ( 2021 ) . Infection and Risk of Parkinson’s disease . Journal of Parkinson's Disease

Program TGPG ( 2021 ) . GP2: The Global Parkinson's Genetics Program . Movement Disorders vol. 36 , ( 4 ) 842 - 851 .

Hone L, Jacobs B, Noyce A, Dobson R ( 2021 ) . Age-specific effects of childhood BMI on multiple sclerosis risk: a Mendelian Randomisation study . MULTIPLE SCLEROSIS JOURNAL . vol. 27 , 764 - 765 .

Senkevich K, Bandres-Ciga S, Yu E, Liyanage UE, Noyce AJ, Gan-Or Z ( 2021 ) . No Evidence for a Causal Relationship Between Cancers and Parkinson's Disease . Journal of Parkinson's Disease vol. 11 , ( 2 ) 801 - 809 .

Simonet C, Galmes MA, Lambert C, Rees RN, Haque T, Bestwick JP, Lees AJ, Schrag A et al. ( 2021 ) . Slow Motion Analysis of Repetitive Tapping (SMART) Test: Measuring Bradykinesia in Recently Diagnosed Parkinson’s Disease and Idiopathic Anosmia . Journal of Parkinson's Disease vol. 11 , ( 4 ) 1901 - 1915 .

Blauwendraat C, Makarious MB, Leonard HL, Bandres-Ciga S, Iwaki MA, Nalls M, Noyce A, Singleton AB ( 2020 ) . A population scale analysis of rare SNCA variation in the UK Biobank . Neurobiology of Disease

Jacobs BM, Smets I, Giovannoni G, Noyce A, Jokubaitis V, Dobson R ( 2020 ) . Regarding: Nicotinic acetylcholine receptors α7 and α9 modify tobacco smoke risk for multiple sclerosis . Multiple Sclerosis Journal vol. 27 , ( 8 ) 1311 - 1312 .

Foote IF, Jacobs BM, Noyce AJ, Korszun A, Bhui KS, Marshall CR ( 2020 ) . Exploring the shared genetic architecture of modifiable risk factors and related endophenotypes of Alzheimer’s disease: A genomic SEM study . Alzheimer's & Dementia vol. 16 , ( S2 )

Noyce AJ, Klein C ( 2020 ) . Genetic Risk of Alzheimer's Disease – Sleepless with the Enemy . Annals of Neurology vol. 89 , ( 1 ) 27 - 29 .

Iwaki H, Blauwendraat C, Leonard HL, Makarious MB, Kim JJ, Liu G, Maple-Grødem J, Corvol JC et al. ( 2020 ) . Differences in the Presentation and Progression of Parkinson's Disease by Sex . Movement Disorders

Auger SD, Jacobs BM, Dobson R, Marshall CR, Noyce AJ ( 2020 ) . Big data, machine learning and artificial intelligence: a neurologist’s guide . Practical Neurology vol. 21 , ( 1 ) 4 - 11 .

Auger S, Jacobs B, Dobson R, MARSHALL C, Noyce A ( 2020 ) . Navigating a world of big data, machine learning and artificial intelligence: a neurologist's guide . Practical Neurology

Jacobs B, Belete D, Bestwick J, Blauwendraat C, Bandres-Ciga S, Heilbron K, Dobson R, International Parkinson’s Disease Genomics Consortium (IPDGC) et al. ( 2020 ) . Parkinson’s disease determinants, prediction and gene-environment interactions in the UK Biobank . Journal of Neurology, Neurosurgery and Psychiatry vol. 91 , 1046 - 1054 .

Cheong J, Goh Z, Marras C, Tanner C, Kasten M, Noyce A, Movement Disorders Society Epidemiology Study Group ( 2020 ) . The impact of COVID-19 on access to Parkinson’s disease medication . Movement Disorders

Noyce A ( 2020 ) . Evaluating lipid-lowering drug targets for Parkinson’s disease prevention with Mendelian randomization . Annals of Neurology

Mencacci NE, Reynolds R, Ruiz SG, Vandrovcova J, Forabosco P, Sánchez-Ferrer A, Volpato V, Botía JA et al. ( 2020 ) . Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders . Brain vol. 143 , ( 9 ) 2771 - 2787 .

Jacobs B, Taylor T, Awad A, Baker D, Giovannoni G, Noyce A, Dobson R ( 2020 ) . Summary-data-based mendelian randomisation prioritises potential druggable targets for Multiple Sclerosis . Brain Communications

Akram N, Li H, Ben-Joseph A, Budu C, Gallagher D, Bestwick JP, Noyce AJ, Simonet C ( 2020 ) . Developing and Validating a New Web-Based Tapping Test for Measuring Distal Bradykinesia in Parkinson’s Disease .

Noyce A ( 2020 ) . Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease . Acta Neuropathologica

Marini K, Mahlknecht P, Tutzer F, Stockner H, Gasperi A, Djamshidian A, Willeit P, Kiechl S et al. ( 2020 ) . Application of a Simple Parkinson's Disease Risk Score in a Longitudinal Population‐Based Cohort . Movement Disorders Article mds.28127 ,

Williams DM, Bandres-Ciga S, Heilbron K, Team TAR, Consortium TIPDG, Hinds D, Noyce AJ ( 2020 ) . Evaluating lipid-lowering drug targets for Parkinson disease prevention with Mendelian randomization .

Cheong J, de Pablo-Fernandez E, Foltynie T, Noyce A ( 2020 ) . The association between type 2 diabetes mellitus and Parkinson’s disease . Journal of Parkinson's Disease

Iwaki H, Blauwendraat C, Leonard HL, Makarious MB, Kim JJ, Liu G, Maple-Grødem J, Corvol J-C et al. ( 2020 ) . Differences in the presentation and progression of Parkinson’s disease by sex .

Bestwick JP, Auger SD, Simonet C, Rees RN, Rack D, Jitlal M, Giovannoni G, Lees AJ et al. ( 2020 ) . Improving estimation of Parkinson’s disease risk - The enhanced PREDICT-PD algorithm .

Auger S, Noyce A ( 2020 ) . Testing shortened versions of smell tests to screen for hyposmia in Parkinson’s disease . Movement Disorders Clinical Practice

Guelfi S, D’Sa K, Botía JA, Vandrovcova J, Reynolds RH, Zhang D, Trabzuni D, Collado-Torres L et al. ( 2020 ) . Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information . Nature Communications vol. 11 , ( 1 )

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Dobson R, Jitlal M, Marshall CR, Noyce AJ, Robson J, Cuzick J, Giovannoni G ( 2020 ) . Ethnic and Socioeconomic Associations with Multiple Sclerosis Risk . Annals of Neurology vol. 87 , ( 4 ) 599 - 608 .

Dobson R, Noyce A, Giovannoni G, jacobs B ( 2020 ) . BMI and low serum vitamin D are causal risk factors for Multiple Sclerosis: a Mendelian Randomisation study . Neurology, Neuroimmunology and Neuroinflammation

Alarcón F, Maldonado J-C, Cañizares M, Molina J, Noyce AJ, Lees AJ ( 2020 ) . Motor Dysfunction as a Prodrome of Parkinson’s Disease . Journal of Parkinson's Disease vol. 10 , ( 3 ) 1067 - 1073 .

Noyce A, Giovannoni G, Scheltens P, Berg D, Brown L, Dierickx K, Frisoni GB, Georges J et al. ( 2020 ) . Time matters in brain health: how should society prepare for a growing population at risk of neurodegenerative diseases? . EUROPEAN JOURNAL OF NEUROLOGY . vol. 27 , 143 - 143 .

Noyce A, Ben-Joseph A, MARSHALL C, Lees A ( 2019 ) . Ethnic variation in the manifestation of Parkinson’s disease: a narrative review . Journal of Parkinson's Disease

Simonet C, Schrag A, Lees AJ, Noyce AJ ( 2019 ) . The motor prodromes of parkinson’s disease: from bedside observation to large-scale application . Journal of Neurology vol. 268 , ( 6 ) 2099 - 2108 .

Nalls MA, Blauwendraat C, Vallerga CL, Heilbron K, Bandres-Ciga S, Chang D, Tan M, Kia DA et al. ( 2019 ) . Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies . The Lancet Neurology vol. 18 , ( 12 ) 1091 - 1102 .

Noyce A, International Parkinson’s Disease Genomics Consortium (IPDGC) ( 2019 ) . Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia . Brain: a journal of neurology

Bandres‐Ciga S, Ahmed S, Sabir MS, Blauwendraat C, Adarmes‐Gómez AD, Bernal‐Bernal I, Bonilla‐Toribio M, Buiza‐Rueda D et al. ( 2019 ) . The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population‐Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight . Movement Disorders vol. 34 , ( 12 ) 1851 - 1863 .

Noyce AJ, Bandres‐Ciga S, Kim J, Heilbron K, Kia D, Hemani G, Xue A, Lawlor DA et al. ( 2019 ) . The Parkinson's Disease Mendelian Randomization Research Portal . Movement Disorders vol. 34 , ( 12 ) 1864 - 1872 .

Bandres-Ciga S, Noyce A, Traynor BJ ( 2019 ) . Mendelian randomization: a journey from obscurity to center stage with a few potholes along the way . JAMA Neurology vol. 77 , ( 7 ) 7 - 8 .

Noyce A, Iwaki H ( 2019 ) . Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts . Movement Disorders

Neligan A, Noyce AJ, Gosavi TD, Shorvon SD, Köhler S, Walker MC ( 2019 ) . Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time . JAMA Neurology vol. 76 , ( 8 ) 897 - 897 .

Iwaki H, Blauwendraat C, Leonard HL, Liu G, Maple-Grødem J, Corvol J-C, Pihlstrøm L, van Nimwegen M et al. ( 2019 ) . Genetic risk of Parkinson disease and progression:: An analysis of 13 longitudinal cohorts . Neurology Genetics vol. 5 , ( 4 )

Hasan H, Burrows M, Athauda DS, Hellman B, James B, Warner T, Foltynie T, Giovannoni G et al. ( 2019 ) . The BRadykinesia Akinesia INcoordination (BRAIN) Tap Test: Capturing the Sequence Effect . Movement Disorders Clinical Practice vol. 6 , ( 6 ) 462 - 469 .

Fernández‐Santiago R, Martín‐Flores N, Antonelli F, Cerquera C, Moreno V, Bandres‐Ciga S, Manduchi E, Tolosa E et al. ( 2019 ) . SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's Disease . Movement Disorders vol. 34 , ( 9 ) 1333 - 1344 .

NOYCE AJ, Neligan A, Gosavi T, Shorvon S, Köhler S, Walker M ( 2019 ) . Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time A Systematic Review and Meta-analysis . JAMA Neurology

Billingsley KJ, Barbosa IA, Bandrés-Ciga S, Quinn JP, Bubb VJ, Deshpande C, Botia JA, Reynolds RH et al. ( 2019 ) . Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset . npj Parkinson's Disease vol. 5 , ( 1 )

Joseph T, Auger SD, Peress L, Rack D, Cuzick J, Giovannoni G, Lees A, Schrag AE et al. ( 2019 ) . Screening performance of abbreviated versions of the UPSIT smell test . Journal of Neurology vol. 266 , ( 8 ) 1897 - 1906 .

Reynolds RH, Botía J, Nalls MA, Hardy J, Gagliano Taliun SA, Ryten M ( 2019 ) . Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability . npj Parkinson's Disease vol. 5 , ( 1 )

NOYCE AJ, International Parkinson's Disease Genomics Consortium (IPDGC) ( 2019 ) . Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms . Movement Disorders

Heilbron K, NOYCE AJ, Fontanillas P, Alipanahi B, Nalls MA, 23andMe Research Team, Cannon P ( 2019 ) . The Parkinson’s Phenome—Traits Associated with Parkinson's Disease in a Broadly Phenotyped Cohort . npj Parkinson's Disease vol. 5 , Article 4 (2019) ,

Schrag A, Anastasiou Z, Ambler G, NOYCE AJ, walters K ( 2019 ) . Predicting Diagnosis of Parkinson’s disease: A Risk Algorithm based on Primary Care presentations . Movement Disorders

NOYCE AJ ( 2019 ) . Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis . Annals of Neurology

Bandres‐Ciga S, Saez‐Atienzar S, Bonet‐Ponce L, Billingsley K, Vitale D, Blauwendraat C, Gibbs JR, Pihlstrøm L et al. ( 2019 ) . The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease . Movement Disorders vol. 34 , ( 4 ) 460 - 468 .

NOYCE AJ, Rees R, Schrag A ( 2018 ) . The prodromes of Parkinson's disease . European Journal of Neuroscience

Kia DA, Sabir MS, Ahmed S, Trinh J, Bandres-Ciga S, Consortium IPDG, Noyce AJ, Kaiyrzhanov R et al. ( 2018 ) . LRP10 in α-synucleinopathies . The Lancet Neurology vol. 17 , ( 12 )

Acharya A, Basnett I, Gutteridge C, Noyce A ( 2018 ) . Laughter isn't always the best medicine . BMJ vol. 363 , k4579 - k4579 .

Blauwendraat C, Reed X, Kia DA, Gan-Or Z, Lesage S, Pihlstrøm L, Guerreiro R, Gibbs JR et al. ( 2018 ) . Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease . JAMA Neurology vol. 75 , ( 11 ) 1416 - 1422 .

Rees RN, Acharya AP, Schrag A, Noyce AJ ( 2018 ) . An early diagnosis is not the same as a timely diagnosis of Parkinson's disease . F1000Research vol. 7 , 1106 - 1106 .

NOYCE AJ ( 2018 ) . Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson’s disease . Annals of Neurology

De Pablo-Fernandez E, Goldacre R, Pakpoor J, Noyce AJ, Warner TT ( 2018 ) . Association between diabetes and subsequent Parkinson disease . Neurology vol. 91 , ( 2 ) e139 - e142 .

Noyce A ( 2018 ) . Remembering the man behind An Essay on the Shaking Palsy . The Lancet Neurology vol. 17 , ( 6 )

Keddie S, Adams A, Kelso ARC, Turner B, Schmierer K, Gnanapavan S, Malaspina A, Giovannoni G et al. ( 2018 ) . No laughing matter: subacute degeneration of the spinal cord due to nitrous oxide inhalation . Journal of Neurology vol. 265 , ( 5 ) 1089 - 1095 .

Weil RS, Schwarzkopf DS, Bahrami B, Fleming SM, Jackson BM, Goch TJC, Saygin AP, Miller LE et al. ( 2018 ) . Assessing cognitive dysfunction in Parkinson's disease: An online tool to detect visuo‐perceptual deficits . Movement Disorders vol. 33 , ( 4 ) 544 - 553 .

NOYCE AJ ( 2018 ) . Assessing cognitive dysfunction in Parkinson’s: An online tool to detect visuo-perceptual deficits . Movement Disorders

Noyce AJ, Dickson J, Rees RN, Bestwick JP, Isaias IU, Politis M, Giovannoni G, Warner TT et al. ( 2018 ) . Dopamine reuptake transporter–single‐photon emission computed tomography and transcranial sonography as imaging markers of prediagnostic Parkinson's disease . Movement Disorders vol. 33 , ( 3 ) 478 - 482 .

Blauwendraat C, Kia DA, Pihlstrøm L, Gan-Or Z, Lesage S, Gibbs JR, Ding J, Alcalay RN et al. ( 2017 ) . Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease . Neurobiology of Aging vol. 64 , 159.e5 - 159.e8 .

Shribman S, Noyce A, Gnanapavan S, Lambourne J, Harrison T, Schon F ( 2017 ) . Cryptococcal meningitis in apparently immunocompetent patients: association with idiopathic CD4+ lymphopenia . Practical Neurology vol. 18 , ( 2 )

Shribman S, Hasan H, Hadavi S, Giovannoni G, Noyce AJ ( 2017 ) . The BRAIN test: a keyboard-tapping test to assess disability and clinical features of multiple sclerosis . Journal of Neurology vol. 265 , ( 2 ) 285 - 290 .

Noyce AJ, Lees A ( 2017 ) . Observations on a 2-Step Approach to Screening for Parkinson Disease . JAMA Neurology vol. 74 , ( 12 ) 1506 - 1506 .

Noyce A, Bandopadhyay R ( 2017 ) . Parkinson's Disease: Basic Pathomechanisms and a Clinical Overview . vol. 15 ,

Raciborska DD, Noyce AJ, Pyne D, Turner BP ( 2017 ) . Lupus myelopathy . Practical Neurologypractneurol-2017-001 - practneurol-2017-001 .

Lynch DS, Loh SHY, Harley J, Noyce AJ, Martins LM, Wood NW, Houlden H, Plun-Favreau H ( 2017 ) . Nonsyndromic Parkinson disease in a family with autosomal dominant optic atrophy due to OPA1 mutations . Neurology Genetics vol. 3 , ( 5 ) e188 - e188 .

Noyce AJ, Kia DA, Hemani G, Nicolas A, Price TR, De Pablo-Fernandez E, Haycock PC, Lewis PA et al. ( 2017 ) . Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study . PLOS Medicine vol. 14 , ( 6 ) e1002314 - e1002314 .

Noyce A, Kia D, Hemani G, Nicolas A, Price T, Fernandez E, Haycock P, Lewis P et al. ( 2017 ) . Increased BMI May Protect against Parkinson's Disease: Evidence From Mendelian Randomisation Study . vol. 32 , Abstract: java.sql.Clob org.hibernate.engine.jdbc.WrappedClob java.io.Serializable ,

Magdalinou NK, Noyce AJ, Pinto R, Lindstrom E, Holmen-Larsson J, Holtta M, Blennow K, Morris HR et al. ( 2017 ) . Identification of candidate cerebrospinal fluid biomarkers in parkinsonism using quantitative proteomics . PARKINSONISM & RELATED DISORDERS vol. 37 , 65 - 71 .

Pakpoor J, Noyce A, Goldacre R, Selkihova M, Mullin S, Schrag A, Lees A, Goldacre M ( 2017 ) . Viral hepatitis and Parkinson disease . Neurology vol. 88 , ( 17 ) 1630 - 1633 .

Noyce AJ, Schrag A, Masters JM, Bestwick JP, Giovannoni G, Lees AJ ( 2017 ) . Subtle motor disturbances in PREDICT-PD participants . J Neurol Neurosurg Psychiatry vol. 88 , ( 3 ) 212 - 217 .

Hasan H, Athauda DS, Foltynie T, Noyce AJ ( 2017 ) . Technologies Assessing Limb Bradykinesia in Parkinson’s Disease . Journal of Parkinson's Disease vol. 7 , ( 1 ) 65 - 77 .

Noyce AJ, R'Bibo L, Peress L, Bestwick JP, Adams-Carr KL, Mencacci NE, Hawkes CH, Masters JM et al. ( 2017 ) . PREDICT-PD: An online approach to prospectively identify risk indicators of Parkinson's disease . Mov Disord vol. 32 , ( 2 ) 219 - 226 .

Noyce A, Dickson J, Bestwick J, Isaias I, Politis M, Giovannoni G, Warner T, Lees A et al. ( 2017 ) . Associations of DAT SPECT and TCS with prodromal features of Parkinson's disease: Results in PREDICT-PD participants . MOVEMENT DISORDERS . vol. 32 ,

Nagy A, Hardaker E, Bestwick J, Giovannoni G, Warner T, Lees A, Schrag A, Noyce A ( 2017 ) . Cognition in the PREDICT-PD Cohort . MOVEMENT DISORDERS . vol. 32 ,

Lubbe SJ, Escott-Price V, Gibbs JR, Nalls MA, Bras J, Price TR, Nicolas A, Jansen IE et al. ( 2016 ) . Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance . Human Molecular Genetics vol. 24 , ddw348 - ddw348 .

Adams-Carr KL, Bestwick JP, Shribman S, Lees A, Schrag A, Noyce AJ ( 2016 ) . Constipation preceding Parkinson's disease: a systematic review and meta-analysis . J Neurol Neurosurg Psychiatry vol. 87 , ( 7 ) 710 - 716 .

Hasan H, Athauda DS, Foltynie T, Giovannoni G, Warner T, Lees AJ, Noyce A ( 2016 ) . Objective decrement in Parkinson's disease - A new parameter for the BRAIN tap test . Movement Disorders . Conference: 20th International Congress of Parkinson's Disease and Movement Disorders ( Berlin, Germany ) from: 19/06/2016 to: 23/06/2016 , vol. 31 , S177 - S177 .

Salat D, Noyce AJ, Schrag A, Tolosa E ( 2016 ) . Challenges of modifying disease progression in prediagnostic Parkinson's disease . The Lancet Neurology vol. 15 , ( 6 ) 637 - 648 .

Mok KY, Sheerin U, Simón-Sánchez J, Salaka A, Chester L, Escott-Price V, Mantripragada K, Doherty KM et al. ( 2016 ) . Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data . The Lancet Neurology vol. 15 , ( 6 ) 585 - 596 .

Noyce AJ, Lees AJ, Schrag A-E ( 2016 ) . The prediagnostic phase of Parkinson's disease . Journal of Neurology, Neurosurgery & Psychiatry vol. 87 , ( 8 ) 871 - 878 .

Masters JM, Noyce AJ, Lynham S, Warner TT, Giovannoni G, Proctor GB ( 2016 ) . A comprehensive characterisation of the salivary proteome of patients with Parkinson's disease . MOVEMENT DISORDERS . vol. 31 , S238 - S239 .

Noyce AJ, Schrag A, Masters J, Bestwick JP, Giovannoni G, Lees AJ ( 2016 ) . Blinded video assessment of subtle Parkinsonian signs in PREDICT-PD participants . MOVEMENT DISORDERS . vol. 31 , S506 - S506 .

Mok KY, Sheerin U, Simon-Sanchez J, Salaka A, Chester L, Escott-Price V, Mantripragada K, Doherty KM et al. ( 2016 ) . Deletions at 22q11.2 in idiopathic Parkinson's disease: A combined analysis of GWAS data . MOVEMENT DISORDERS . vol. 31 , S221 - S222 .

R'Bibo L, Mencacci NE, Schrag A, Bestwick JP, Peress L, Masters J, Giovannoni G, Lees AJ et al. ( 2016 ) . Exploring association of GBA variants with pre-diagnostic features of PD in the PREDICT-PD cohort: A nested case-control study . MOVEMENT DISORDERS . vol. 31 , S125 - S125 .

Simonet C, Noyce AJ, Ling H, Lees AJ, Warner TT ( 2016 ) . Handwriting in Parkinson's disease: Systematic review and preliminary study . MOVEMENT DISORDERS . vol. 31 , S508 - S508 .

Osborne CW, Bestwick J, Giovannoni G, Lees AJ, Schrag A, Noyce A ( 2016 ) . Participant feedback in the PREDICT-PD study . MOVEMENT DISORDERS . vol. 31 , S594 - S594 .

Noyce AJ, Nalls MA ( 2015 ) . Mendelian Randomization — the Key to Understanding Aspects of Parkinson's Disease Causation? . Movement Disorders vol. 31 , ( 4 ) 478 - 483 .

Noyce A, Bestwick J, Mencacci N, Hawkes C, Hardy J, Giovannoni G, Lees A, Schrag A ( 2015 ) . PREDICT-PD: Identifying Risk of Parkinson's disease in the Community . MOVEMENT DISORDERS . vol. 30 , 1989 - 1989 .

Masters JM, Bestwick J, Warner TT, Giovannoni G, Proctor GB, Noyce AJ ( 2015 ) . Systematic review and meta‐analysis of salivary protein concentration in Parkinson's disease . Movement Disorders vol. 30 , ( 14 ) 1971 - 1972 .

Adams-Carr K, Schrag A, Shribman S, Bestwick J, Lees A, Noyce A ( 2015 ) . CONSTIPATION PRECEDING PARKINSON'S DISEASE–META-ANALYSIS . Journal of Neurology Neurosurgery & Psychiatry . vol. 86 ,

Masters J, Noyce A, Giovannoni G, Warner T, Proctor G ( 2015 ) . ELEVATED SALIVARY DJ-1 IN PARKINSON'S DISEASE IS ASSOCIATED WITH ALTERED SALIVARY SECRETION . Journal of Neurology Neurosurgery & Psychiatry . vol. 86 ,

Nalls MA, McLean CY, Rick J, Eberly S, Hutten SJ, Gwinn K, Sutherland M, Martinez M et al. ( 2015 ) . Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study . The Lancet Neurology vol. 14 , ( 10 ) 1002 - 1009 .

Masters JM, Noyce AJ, Warner TT, Giovannoni G, Proctor GB ( 2015 ) . Elevated salivary protein in Parkinson's disease and salivary DJ-1 as a potential marker of disease severity . Parkinsonism & Related Disorders vol. 21 , ( 10 ) 1251 - 1255 .

Noyce AJ, Mencacci NE, Schrag A, Bestwick JP, Giovannoni G, Lees AJ, Hardy J ( 2015 ) . Web‐based assessment of Parkinson's prodromal markers identifies GBA variants . Movement Disorders vol. 30 , ( 7 ) 1002 - 1003 .

Nagy A, Noyce A, Velayos-Baeza A, Lees AJ, Warner TT, Ling H ( 2015 ) . Late Emergence of Parkinsonian Phenotype and Abnormal Dopamine Transporter Scan in Chorea‐Acanthocytosis . Movement Disorders Clinical Practice vol. 2 , ( 2 ) 182 - 186 .

Adams-Carr KL, Schrag A, Shribman S, Bestwick JP, Lees A, Noyce AJ ( 2015 ) . Constipation preceding Parkinson's disease - Systematic review and meta-analysis . MOVEMENT DISORDERS . vol. 30 , S149 - S149 .

Masters JM, Noyce AJ, Giovannoni G, Warner TT, Proctor GB ( 2015 ) . Elevated salivary DJ-1 in Parkinson's disease is associated with altered salivary secretion . MOVEMENT DISORDERS . vol. 30 , S169 - S170 .

Athauda DS, Hasan H, Noyce A, Foltynie T ( 2015 ) . Evaluating the use of the online bradykinesia-akinesia Incoordination (BRAIN) test in Parkinson's disease in "on" and "off" states . MOVEMENT DISORDERS . vol. 30 , S414 - S415 .

Magdalinou N, Ling H, Noyce A, Massey L, Paterson R, Schott J, Davagnanam I, Micallef C et al. ( 2015 ) . The visual estimation of midbrain to pons ratio combined with cerebrospinal fluid biomarkers improves the diagnostic accuracy of PSP . MOVEMENT DISORDERS . vol. 30 , S321 - S321 .

Schrag A, Horsfall L, Walters K, Noyce A, Petersen I ( 2014 ) . Prediagnostic presentations of Parkinson's disease in primary care: a case-control study . The Lancet Neurology vol. 14 , ( 1 ) 57 - 64 .

Torsney KM, Noyce AJ, Doherty KM, Bestwick JP, Dobson R, Lees AJ ( 2014 ) . Bone health in Parkinson's disease: a systematic review and meta-analysis . J Neurol Neurosurg Psychiatry vol. 85 , ( 10 ) 1159 - 1166 .

Osborne C, Noyce A, Sylvester R ( 2014 ) . AUTO-REGULATION ICP IN IIH DUE TO CHRONIC CSF LEAK . Journal of Neurology Neurosurgery & Psychiatry . vol. 85 , e4 - e4 .

Mencacci NE, Isaias IU, Reich MM, Ganos C, Plagnol V, Polke JM, Bras J, Hersheson J et al. ( 2014 ) . Parkinson's disease in GTP cyclohydrolase 1 mutation carriers . Brain vol. 137 , ( Pt 9 ) 2480 - 2492 .

Staff TPO ( 2014 ) . Correction: Bradykinesia-Akinesia Incoordination Test: Validating an Online Keyboard Test of Upper Limb Function . PLOS ONE vol. 9 , ( 8 )

Osborne C, Stallworthy S, Evanson J, Sylvester R, Noyce AJ ( 2014 ) . Rapid-onset flaccid paraplegia caused by multiple myeloma dumbbell tumour . Pract Neurol vol. 14 , ( 4 ) 268 - 269 .

Shribman S, Torsney KM, Noyce AJ, Giovannoni G, Fearnley J, Dobson R ( 2014 ) . A service development study of the assessment and management of fracture risk in Parkinson's disease . J Neurol vol. 261 , ( 6 ) 1153 - 1159 .

Shribman SE, Torsney K, Noyce AJ, Giovannoni G, Fearnley J, Dobson R ( 2014 ) . A service development study of the assessment and management of fracture risk in Parkinson's disease . MOVEMENT DISORDERS . vol. 29 , S192 - S192 .

Torsney KM, Noyce AJ, Doherty KM, Bestwick JP, Dobson R, Lees AJ ( 2014 ) . A systematic review and meta-analysis of fracture risk in Parkinson's disease . MOVEMENT DISORDERS . vol. 29 , S551 - S551 .

Torsney KM, Noyce AJ, Doherty KM, Bestwick JP, Dobson R, Lees AJ ( 2014 ) . Bone health in Parkinson's disease: A systematic review and meta-analysis . MOVEMENT DISORDERS . vol. 29 , S551 - S551 .

Noyce AJ, Nagy A, Acharya S, Hadavi S, Bestwick JP, Fearnley J, Lees AJ, Giovannoni G ( 2014 ) . Bradykinesia-akinesia incoordination test: validating an online keyboard test of upper limb function . PLoS One vol. 9 , ( 4 )

Noyce AJ, Mencacci N, Schrag A, Giovannoni G, Lees AJ, Hardy J ( 2014 ) . GBA1 and LRRK2 mutations in higher and lower risk subjects from the PREDICT-PD project . MOVEMENT DISORDERS . vol. 29 , S58 - S59 .

Nalls MA, Saad M, Noyce AJ, Keller MF, Schrag A, Bestwick JP, Traynor BJ, Gibbs JR et al. ( 2014 ) . Genetic comorbidities in Parkinson's disease . HUMAN MOLECULAR GENETICS vol. 23 , ( 3 ) 831 - 841 .

Mencacci NE, Isaias IU, Reich MM, Ganos C, Plagnol V, Polke JM, Bras J, Stamelou M et al. ( 2014 ) . Parkinson's disease in GTP cyclohydrolase-1 mutation carriers . MOVEMENT DISORDERS . vol. 29 , S57 - S57 .

Shribman SE, Noyce AJ, Martin JE, Giovannoni G, Knowles CH ( 2014 ) . The distribution of α-synuclein in the enteric nervous system: An immunohistochemical study on colonic resections from 24 control and 4 Parkinson's disease patients . MOVEMENT DISORDERS . vol. 29 , 1839 - 1839 .

Nagy A, Noyce A, Lees A, Warner T, Ling H ( 2014 ) . Two cases of abnormal dopamine transporter scan in chorea-acanthocytosis . MOVEMENT DISORDERS . vol. 29 , S195 - S196 .

Hadavi S, Shribman S, Nagy A, Acharya S, Fearnley J, Dobson R, Lees A, Giovannoni G et al. ( 2013 ) . The bradykinesia-akinesia incoordination test: a simple objective test in multiple sclerosis . J Neurol Neurosurg Psychiatry vol. 84 , ( 11 )

Noyce AJ, Bestwick JP, Silveira-Moriyama L, Hawkes CH, Knowles CH, Hardy J, Giovannoni G, Nageshwaran S et al. ( 2013 ) . PREDICT-PD: Identifying risk of Parkinson's disease in the community: methods and baseline results . Journal of Neurology Neurosurgery & Psychiatry vol. 85 , ( 1 )

Dobson R, Yarnall A, Noyce AJ, Giovannoni G ( 2013 ) . Bone health in chronic neurological diseases: a focus on Multiple sclerosis and Parkinsonian syndromes . Pract Neurol vol. 13 , ( 2 ) 70 - 79 .

Nagy A, Acharya S, Hadavi S, Bestwick JP, Fearnley J, Lees AJ, Giovannoni G, Noyce AJ ( 2013 ) . Bradykinesia-akinesia incoordination test: Validating an online keyboard test of upper limb function . MOVEMENT DISORDERS . vol. 28 , S114 - S114 .

Djamshidian A, O'Sullivan SS, Foltynie T, Aviles-Olmos I, Limousin P, Noyce A, Zrinzo L, Lees AJ et al. ( 2013 ) . Dopamine agonists rather than deep brain stimulation cause reflection impulsivity in Parkinson's disease . MOVEMENT DISORDERS . vol. 28 , S130 - S130 .

Djamshidian A, O'Sullivan SS, Foltynie T, Aviles-Olmos I, Limousin P, Noyce A, Zrinzo L, Lees AJ et al. ( 2013 ) . Dopamine agonists rather than deep brain stimulation cause reflection impulsivity in Parkinson's disease . J Parkinsons Dis vol. 3 , ( 2 ) 139 - 144 .

Noyce AJ, Bestwick JP, Silveira-Moriyama L, Hawkes CH, Knowles C, Hardy J, Giovannoni G, Nageshwaran S et al. ( 2013 ) . PREDICT-PD study: Online screening algorithm identifying Parkinson's disease risk . MOVEMENT DISORDERS . vol. 28 , S389 - S389 .

Noyce AJ, Bestwick JP, Silveira-Moriyama L, Hawkes CH, Giovannoni G, Lees AJ, Schrag A ( 2012 ) . Meta-analysis of early nonmotor features and risk factors for Parkinson disease . Ann Neurol vol. 72 , ( 6 ) 893 - 901 .

Chan MV, Bubb KJ, Noyce A, Villar IC, Duchene J, Hobbs AJ, Scotland RS, Ahluwalia A ( 2012 ) . Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation . Br J Pharmacol vol. 167 , ( 4 ) 805 - 817 .

Noyce AJ, Silveira-Moriyama L, Gilpin P, Ling H, Howard R, Lees AJ ( 2012 ) . Severe dysphagia as a presentation of Parkinson's disease . Mov Disord vol. 27 , ( 3 ) 457 - 458 .

Doherty KM, Silveira-Moriyama L, Nisbet A, Noyce A, Quinn N, Parton M, Lees AJ ( 2012 ) . 0854 Camptocormia: what is the cause? . Journal of Neurology Neurosurgery & Psychiatry . vol. 83 ,

Noyce A, Silveira-Moriyama L, Lees AJ, Schrag A, Bestwick J, Hawkes CH, Giovannoni G, Hardy J et al. ( 2012 ) . A PILOT STUDY OF AN ALGORITHM DESIGNED TO IDENTIFY PARKINSON'S DISEASE IN THE EARLY, NON-MOTOR PHASE . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY . vol. 83 ,

Noyce A, Bestwick J, Hawkes CH, Knowles CH, Hardy J, Lees AJ, Silveira-Moriyama L, Giovannoni G et al. ( 2012 ) . AN ALGORITHM TO IDENTIFY INDIVIDUALS AT HIGH-RISK OF PARKINSON'S DISEASE IN THE COMMUNITY . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY . vol. 83 ,

Noyce AJ, Bestwick J, Silveira-Moriyama L, Hawkes CH, Giovannoni G, Lees AJ, Schrag A ( 2012 ) . Risk factors and early non-motor features for Parkinson's disease: A systematic review and meta-analysis . MOVEMENT DISORDERS . vol. 27 , S4 - S4 .

Noyce A, Treacy C, Budu C, Fearnley J, Lees AJ, Giovannoni G ( 2012 ) . THE NEW BRADYKINESIA AKINESIA INCOORDINATION (BRAIN) TEST: AN ONLINE TEST OF UPPER LIMB MOVEMENT . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY . vol. 83 ,

Acharya S, Nagy A, Budu C, Treacy C, Fearnley J, Lees AJ, Giovannoni G, Noyce AJ ( 2012 ) . The new bradykinesia akinesia incoordination (BRAIN) test: People with Parkinson's disease versus healthy controls . MOVEMENT DISORDERS . vol. 27 , S102 - S102 .

Hadavi S, Noyce AJ, Leslie RD, Giovannoni G ( 2011 ) . Stiff person syndrome . Pract Neurol vol. 11 , ( 5 ) 272 - 282 .

Noyce AJ, Treacy C, Budu C, Fearnley J, Lees AJ, Giovannoni G ( 2011 ) . The new Bradykinesia Akinesia Incoordination (BRAIN) test: Preliminary data from an online test of upper limb movement . Movement Disorders vol. 27 , ( 1 ) 157 - 158 .

Doherty KM, Noyce AJ, Silveira-Moriyama L, Nisbet A, Quinn N, Lees AJ ( 2011 ) . Familial camptocormia: from dystonia to myopathy . Journal of Neurology Neurosurgery & Psychiatry vol. 83 , ( 3 )

Noyce AJ, Bestwick J, Hawkes CH, Schrag A, Knowles CH, Hardy J, Lees AJ, Giovannoni G et al. ( 2011 ) . A pilot study of an algorithm designed to identify Parkinson's disease in the early, non-motor phase . MOVEMENT DISORDERS . vol. 26 , S54 - S54 .

Noyce AJ, Bestwick J, Hawkes CH, Knowles CH, Hardy J, Lees AJ, Silveira-Moriyama L, Giovannoni G et al. ( 2011 ) . An algorithm to identify individuals at high-risk of Parkinson's disease in the community . MOVEMENT DISORDERS . vol. 26 , S54 - S55 .

Hadavi SY, Bahra M, Noyce AJ, Webb A ( 2011 ) . POTENTIAL FOR SERIOUS UNDER-REPORTING OF PRESCRIBING ERRORS BY NEWLY-QUALIFIED DOCTORS . BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY . vol. 109 , 159 - 159 .

Noyce AJ, Gilpin P, Howard R, Lees AJ, Silviera-Moriyama L ( 2011 ) . Severe dysphagia preceding Parkinson's disease . MOVEMENT DISORDERS . vol. 26 , S195 - S196 .

Noyce AJ, McCrae S, Gawler J, Evanson J ( 2010 ) . Teaching NeuroImages: microhemorrhages resulting from cranial radiotherapy in childhood . Neurology vol. 75 , ( 1 ) e2 - e3 .

Shah M, Deeb J, Fernando M, Noyce A, Visentin E, Findley LJ, Hawkes CH ( 2009 ) . Abnormality of taste and smell in Parkinson's disease . Parkinsonism Relat Disord vol. 15 , ( 3 ) 232 - 237 .

Shah M, Deeb J, Fernando M, Visentin E, Noyce A, Findley LJ, Hawkes CH ( 2007 ) . Taste is abnormal in Parkinson disease and suggests cortical spread . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY . vol. 78 , 1024 - 1024 .

Noyce AL, Hetley RS, Dobias JJ, Stine WW ( 2007 ) . Perception of local rigidity due to lines in rotating random-dot textures viewed through an aperture . PERCEPTION . vol. 36 , 204 - 204 .

Shah M, Deeb J, Fernando M, Visentin E, Noyce A, Findley LJ, Hawkes CH ( 2007 ) . Taste threshold is abnormal in Parkinson's disease and suggests cortical spread . MOVEMENT DISORDERS . vol. 22 , S199 - S199 .

Shah M, Noyce A, Deeb J, Findley LJ, Hawkes CH ( 2006 ) . Chemosensory measurement in essential tremor . JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY . vol. 77 , 1397 - 1397 .

Shah M, Noyce A, Deeb J, Findley LJ, Hawkes CH ( 2006 ) . Smell identification and taste threshold are normal in essential tremor . CHEMICAL SENSES . vol. 31 , E27 - E27 .

Shah M, Noyce A, Deeb J, Findley LJ, Hawkes CH ( 2006 ) . Chemosensory measurement in essential tremor . EUR J NEUROL vol. 13 , 212 - 212 .

Noyce A, Shah M, Deeb J, Findley LJ, Hawkes CH ( 2006 ) . Chemosensory measurement in essential tremor . CHEMICAL SENSES . vol. 31 , A30 - A31 .