Publications: Mr Alastair Noyce
Sanyaolu AO, Mohamed W, Makarious MB, August JL, Kekenadze M, Heilbron K, Periñán MT, Noyce A et al.
(
2025
)
.
Chapter 4 Mendelian randomization and Parkinson’s disease
.
Integrative Omics in Parkinson's Disease
,
Elsevier
Kim JJ, Bandres-Ciga S, Heilbron K, Blauwendraat C, Noyce AJ
(
2024
)
.
Bidirectional relationship between olfaction and Parkinson’s disease
.
npj Parkinson's Disease
vol.
10
,
(
1
)
Tan AH, Saffie-Awad P, Schuh AFS, Lim S-Y, Madoev H, Ahmad-Annuar A, Solle J, Wegel CE et al.
(
2024
)
.
Global Perspectives on Returning Genetic Research Results in Parkinson Disease
.
Neurology Genetics
vol.
10
,
(
6
)
Brolin KA, Schaeffer E, Kuri A, Rumrich IK, Schuh AFS, Darweesh SKL, Kaasinen V, Tolppanen A et al.
(
2024
)
.
Environmental Risk Factors for Parkinson's Disease: A Critical Review and Policy Implications
.
Movement Disorders
Bramich S, Noyce A, Pérez-Carbonell L, Bindoff A, Wang X, King A, Naismith S, Vickers J et al.
(
2024
)
.
P027 Dream characteristics are sex-specific in REM Sleep Behaviour Disorder and healthy older adults
.
SLEEP Advances
vol.
5
,
(
Supplement_1
)
a38
-
a39
.
Mahlknecht P, Leiter S, Horlings C, Schwarzová K, Egner I, Stockner H, Marini K, Theyer C et al.
(
2024
)
.
Preferences regarding Disclosure of Risk for Parkinson's Disease in a Population‐based Study
.
Movement Disorders Clinical Practice
Azoidou V, Noyce AJ, Simonet C
(
2024
)
.
The effect of tactile cueing on dual task performance in Parkinson’s disease. A systematic review and meta-analysis
.
Clinical Parkinsonism & Related Disorders
vol.
11
,
Step K, Eltaraifee E, Elsayed I, Rasaholiarison N, Okubadejo N, Walker R, Mohamed W, Rizig M et al.
(
2024
)
.
Advancing Parkinson's Disease Research in Africa: A Strategic Training Framework of the Global Parkinson's Genetics Program
.
Movement Disorders
Lim S-Y, Tan AH, Ahmad-Annuar A, Okubadejo NU, Lohmann K, Morris HR, Toh TS, Tay YW et al.
(
2024
)
.
Uncovering the genetic basis of Parkinson's disease globally: from discoveries to the clinic
.
The Lancet Neurology
vol.
23
,
(
12
)
1267
-
1280
.
Schaeffer E, Yilmaz R, St. Louis EK, Noyce AJ
(
2024
)
.
Ethical Considerations for Identifying Individuals in the Prodromal/Early Phase of Parkinson’s Disease: A Narrative Review
.
Journal of Parkinson's Disease
vol.
14
,
(
s2
)
s307
-
s319
.
Pereira GM, Teixeira-dos-Santos D, Soares NM, Marconi GA, Friedrich DC, Saffie Awad P, Santos-Lobato BL, Brandão PRP et al.
(
2024
)
.
A systematic review and meta-analysis of the prevalence of Parkinson’s disease in lower to upper-middle-income countries
.
npj Parkinson's Disease
vol.
10
,
(
1
)
Joerres C, Patyjewicz M, Cetin M, Bariana T, Onen B, Hone L, Green J, Tambe D et al.
(
2024
)
.
Assessing the prevalence of nitrous oxide usage in patients aged 35 years or under presenting with unprovoked VTE between 2021-2023
.
Thrombosis Update
vol.
16
,
Araújo R, Noyce AJ, Bloem BR
(
2024
)
.
Therapeutic ancillary examinations in clinical neurology
.
Journal of Neurology
vol.
271
,
(
10
)
7026
-
7029
.
Lázaro‐Figueroa A, Hernández‐Medrano AJ, Ramírez‐Pineda DB, Cadavid AN, Makarious M, Foo JN, Alvarado CX, Bandres‐Ciga S et al.
(
2024
)
.
Is SH3GL2 p.G276V the Causal Functional Variant Underlying Parkinson's Disease Risk at this Locus?
.
Movement Disorders
vol.
39
,
(
11
)
2117
-
2119
.
Rudd KD, Lawler K, Callisaya ML, Bindoff AD, Chiranakorn-Costa S, Li R, McDonald JS, Salmon K et al.
(
2024
)
.
Hand Motor Dysfunction Is Associated with Both Subjective and Objective Cognitive Impairment across the Dementia Continuum
.
Dementia and Geriatric Cognitive Disorders1
-
11
.
Francis M, Zirra A, Haque T, Gallagher D, Budu C, Lees AJ, Schrag A, Noyce AJ et al.
(
2024
)
.
Rapid Voluntary Blinking as a Clinical Marker of Parkinson’s Disease
.
Journal of Parkinson's Disease
vol.
14
,
(
5
)
993
-
997
.
Zhang Q, Noyce AJ, Robson J, Giovannoni G, Marshall CR, Dobson R
(
2024
)
.
No association between oral contraceptive exposure and subsequent MS: A population-based nested case–control study in primary care
.
Multiple Sclerosis Journal
vol.
30
,
(
9
)
1221
-
1226
.
Zaloum SA, Paris A, Mair D, Gutteridge C, Ayling RM, Onen BL, Walton J, Workman A et al.
(
2024
)
.
Evaluation of an ambulatory care pathway for patients with nitrous oxide-induced myeloneuropathy
.
BMJ Neurology Open
vol.
6
,
(
1
)
Li X, Gill A, Panzarasa P, Bestwick J, Schrag A, Noyce A, De Simoni A
(
2024
)
.
Web Application to Enable Online Social Interactions in a Parkinson Disease Risk Cohort: Feasibility Study and Social Network Analysis
.
JMIR Formative Research
Rees RN, Noyce AJ, Schrag AE
(
2024
)
.
Identification of Prodromal Parkinson Disease
.
Neurology
vol.
102
,
(
11
)
Patyjewicz M, Mair D, Zaloum SA, Onen B, Walton J, Dobson R, Joerres C, Shah AM et al.
(
2024
)
.
Recreational nitrous oxide and thrombotic events: a case series
.
BMJ Neurology Open
vol.
6
,
(
1
)
Badenoch JB, Paris A, Jacobs BM, Noyce AJ, Marshall CR, Waters S
(
2024
)
.
Neuroanatomical and prognostic associations of depression in Parkinson’s disease
.
Journal of Neurology Neurosurgery & Psychiatry
vol.
95
,
(
10
)
Chang Y-H, Periñan MT, Wilson M, Noyce AJ
(
2024
)
.
AccessPD as a next generation registry to accelerate Parkinson’s disease research
.
npj Parkinson's Disease
vol.
10
,
(
1
)
Simonet C, Pérez‐Carbonell L, Galmés‐Ordinas MA, Huxford BFR, Chohan H, Gill A, Leschziner G, Lees AJ et al.
(
2024
)
.
The Motor Dysfunction Seen in Isolated REM Sleep Behavior Disorder
.
Movement Disorders
vol.
39
,
(
6
)
1054
-
1059
.
Ojo OO, Bandres‐Ciga S, Makarious MB, Crea PW, Hernandez DG, Houlden H, Rizig M, Singleton AB et al.
(
2024
)
.
GBA1 rs3115534 Is Associated with REM Sleep Behavior Disorder in Parkinson's Disease in Nigerians
.
Movement Disorders
vol.
39
,
(
4
)
728
-
733
.
Lucas A, Noyce AJ, Gernez E, Khoury JME, Garcon G, Cavalier E, Antherieu S, Grzych G
(
2024
)
.
Nitrous oxide abuse direct measurement for diagnosis and follow-up: update on kinetics and impact on metabolic pathways
.
Clinical Chemistry and Laboratory Medicine
vol.
62
,
(
12
)
2356
-
2372
.
Reynoso A, Torricelli R, Jacobs BM, Shi J, Aslibekyan S, Norcliffe‐Kaufmann L, Noyce AJ, Heilbron K
(
2024
)
.
Gene–Environment Interactions for Parkinson's Disease
.
Annals of Neurology
vol.
95
,
(
4
)
677
-
687
.
Kim JJ, Vitale D, Otani DV, Lian MM, Heilbron K, Iwaki H, Lake J, Solsberg CW et al.
(
2023
)
.
Multi-ancestry genome-wide association meta-analysis of Parkinson’s disease
.
Nature Genetics
vol.
56
,
(
1
)
27
-
36
.
Gonzalez‐Robles C, Bartlett M, Burnell M, Clarke CS, Haar S, Hu MT, Huxford B, Jha A et al.
(
2023
)
.
Embedding Patient Input in Outcome Measures for Long‐Term Disease‐Modifying Parkinson Disease Trials
.
Movement Disorders
vol.
39
,
(
2
)
433
-
438
.
Gernez E, Lucas A, Niguet J, Bennis A, Diesnis R, Noyce AJ, Grzych G
(
2023
)
.
What biological markers could be used for diagnosis and monitoring of nitrous oxide abuse?
.
European Journal of Neurology
vol.
31
,
(
3
)
Bramich S, Noyce AJ, King AE, Naismith SL, Kuruvilla MV, Lewis SJG, Roccati E, Bindoff AD et al.
(
2023
)
.
Isolated rapid eye movement sleep behaviour disorder (iRBD) in the Island Study Linking Ageing and Neurodegenerative Disease (ISLAND) Sleep Study: protocol and baseline characteristics
.
Journal of Sleep Research
vol.
33
,
(
3
)
Toffoli M, Chohan H, Mullin S, Jesuthasan A, Yalkic S, Koletsi S, Menozzi E, Rahall S et al.
(
2023
)
.
Phenotypic effect of GBA1 variants in individuals with and without Parkinson's disease: The RAPSODI study
.
Neurobiology of Disease
vol.
188
,
Mair D, Zaloum SA, Patel F, Noyce AJ
(
2023
)
.
Effectiveness of interactive workshops to raise awareness of the neurological harms associated with nitrous oxide use: a cross-sectional study
.
The Lancet
vol.
402
,
Bernard Healey SA, Giovannoni G, Noyce A, Dobson R, Jacobs BM
(
2023
)
.
Impact of multiple sclerosis risk alleles on the plasma proteome
.
Brain
vol.
147
,
(
2
)
e17
-
e21
.
Paris A, Mair D, Zaloum S, Onen B, Noyce AJ
(
2023
)
.
Nitrous oxide and its neurological harms
.
The Lancet Neurology
vol.
22
,
(
10
)
Gonzalez-Robles C, Weil RS, van Wamelen D, Bartlett M, Burnell M, Clarke CS, Hu MT, Huxford B et al.
(
2023
)
.
Outcome Measures for Disease-Modifying Trials in Parkinson’s Disease: Consensus Paper by the EJS ACT-PD Multi-Arm Multi-Stage Trial Initiative
.
Journal of Parkinson's Disease
vol.
13
,
(
6
)
1011
-
1033
.
Jacobs BM, Tank P, Bestwick JP, Noyce AJ, Marshall CR, Mathur R, Giovannoni G, Dobson R
(
2023
)
.
Modifiable risk factors for multiple sclerosis have consistent directions of effect across diverse ethnic backgrounds: a nested case–control study in an English population-based cohort
.
Journal of Neurology
vol.
271
,
(
1
)
241
-
253
.
Wang X, St George RJ, Bindoff AD, Noyce AJ, Lawler K, Roccati E, Bartlett L, Tran SN et al.
(
2023
)
.
Estimating presymptomatic episodic memory impairment using simple hand movement tests: A cross‐sectional study of a large sample of older adults
.
Alzheimer's & Dementia
vol.
20
,
(
1
)
173
-
182
.
Simonet C, Mahlknecht P, Marini K, Seppi K, Gill A, Bestwick JP, Lees AJ, Giovannoni G et al.
(
2023
)
.
The Emergence and Progression of Motor Dysfunction in Individuals at Risk of Parkinson's Disease
.
Movement Disorders
vol.
38
,
(
9
)
1636
-
1644
.
Noyce A
(
2023
)
.
Nitrous oxide-induced myeloneuropathy: a case series
.
Journal of Neurology, Neurosurgery and Psychiatry
Leonard HL, Murtadha R, Martinez-Carrasco A, Jama A, Müller-Nedebock AC, Gil-Martinez A-L, Illarionova A, Moore A et al.
(
2023
)
.
Author Correction: The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data
.
npj Parkinson's Disease
vol.
9
,
(
1
)
Jacobs BM, Schalk L, Dunne A, Scalfari A, Nandoskar A, Gran B, Mein CA, Sellers C et al.
(
2023
)
.
ADAMS project: a genetic Association study in individuals from Diverse Ancestral backgrounds with Multiple Sclerosis based in the UK
.
BMJ Open
vol.
13
,
(
5
)
Senkevich K, Alipour P, Chernyavskaya E, Yu E, Noyce AJ, Gan‐Or Z
(
2023
)
.
Potential Protective Link Between Type I Diabetes and Parkinson's Disease Risk and Progression
.
Movement Disorders
vol.
38
,
(
7
)
1350
-
1355
.
Pérez‐Carbonell L, Simonet C, Chohan H, Gill A, Leschziner G, Schrag A, Noyce AJ
(
2023
)
.
The Views of Patients with Isolated Rapid Eye Movement Sleep Behavior Disorder on Risk Disclosure
.
Movement Disorders
vol.
38
,
(
6
)
1089
-
1093
.
Alvarez Jerez P, Alcantud JL, de los Reyes-Ramírez L, Moore A, Ruz C, Vives Montero F, Rodriguez-Losada N, Saini P et al.
(
2023
)
.
Exploring the genetic and genomic connection underlying neurodegeneration with brain iron accumulation and the risk for Parkinson’s disease
.
npj Parkinson's Disease
vol.
9
,
(
1
)
Leonard HL, Murtadha R, Martinez-Carrasco A, Jama A, Müller-Nedebock AC, Gil-Martinez A-L, Illarionova A, Moore A et al.
(
2023
)
.
The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data
.
npj Parkinson's Disease
vol.
9
,
(
1
)
Foltynie T, Gandhi S, Gonzalez-Robles C, Zeissler M-L, Mills G, Barker R, Carpenter J, Schrag A et al.
(
2023
)
.
Towards a multi-arm multi-stage platform trial of disease modifying approaches in Parkinson’s disease
.
Brain
vol.
146
,
(
7
)
2717
-
2722
.
Paris A, Lake L, Joseph A, Workman A, Walton J, Hayton T, Evangelou N, Lilleker JB et al.
(
2023
)
.
Nitrous oxide-induced subacute combined degeneration of the cord: diagnosis and treatment
.
Practical Neurology
vol.
23
,
(
3
)
222
-
228
.
Nagy AV, Leschziner G, Eriksson SH, Lees A, Noyce AJ, Schrag A
(
2023
)
.
Cognitive impairment in REM-sleep behaviour disorder and individuals at risk of Parkinson's disease
.
Parkinsonism & Related Disorders
vol.
109
,
Frisoni GB, Altomare D, Ribaldi F, Villain N, Brayne C, Mukadam N, Abramowicz M, Barkhof F et al.
(
2023
)
.
Dementia prevention in memory clinics: recommendations from the European task force for brain health services
.
The Lancet Regional Health - Europe
vol.
26
,
Noyce A
(
2022
)
.
The association between anti-epileptic drugs and incident Parkinson’s disease in UK Biobank
.
JAMA Neurology
Bramich S, Verdi K, Salmon K, Noyce A, Alty J
(
2022
)
.
REM sleep behaviour disorder: the importance of early identification in primary care
.
British Journal of General Practice
vol.
73
,
(
726
)
40
-
42
.
Dadu A, Satone V, Kaur R, Hashemi SH, Leonard H, Iwaki H, Makarious MB, Billingsley KJ et al.
(
2022
)
.
Identification and prediction of Parkinson’s disease subtypes and progression using machine learning in two cohorts
.
npj Parkinson's Disease
vol.
8
,
(
1
)
Krohn L, Heilbron K, Blauwendraat C, Reynolds RH, Yu E, Senkevich K, Rudakou U, Estiar MA et al.
(
2022
)
.
Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects
.
Nature Communications
vol.
13
,
(
1
)
Zirra A, Rao SC, Bestwick J, Rajalingam R, Marras C, Blauwendraat C, Mata IF, Noyce AJ
(
2022
)
.
Gender Differences in the Prevalence of Parkinson's Disease
.
Movement Disorders Clinical Practice
vol.
10
,
(
1
)
86
-
93
.
Periñán MT, Brolin K, Bandres‐Ciga S, Blauwendraat C, Klein C, Gan‐Or Z, Singleton A, Gomez‐Garre P et al.
(
2022
)
.
Effect Modification between Genes and Environment and Parkinson's Disease Risk
.
Annals of Neurology
vol.
92
,
(
5
)
715
-
724
.
Jacobs BM, Peter M, Giovannoni G, Noyce AJ, Morris HR, Dobson R
(
2022
)
.
Towards a global view of multiple sclerosis genetics
.
Nature Reviews Neurology
vol.
18
,
(
10
)
613
-
623
.
Kent DM, Leung LY, Puttock EJ, Wang AY, Luetmer PH, Kallmes DF, Nelson J, Fu S et al.
(
2022
)
.
Development of Parkinson Disease and Its Relationship with Incidentally Discovered White Matter Disease and Covert Brain Infarction in a Real‐World Cohort
.
Annals of Neurology
vol.
92
,
(
4
)
620
-
630
.
Schumacher‐Schuh AF, Bieger A, Okunoye O, Mok KY, Lim S, Bardien S, Ahmad‐Annuar A, Santos‐Lobato BL et al.
(
2022
)
.
Underrepresented Populations in Parkinson's Genetics Research: Current Landscape and Future Directions
.
Movement Disorders
vol.
37
,
(
8
)
1593
-
1604
.
Day JO, Smith S, Noyce AJ, Alty J, Jeffery A, Chapman R, Carroll C
(
2022
)
.
Challenges of Incorporating Digital Health Technology Outcomes in a Clinical Trial: Experiences from PD STAT
.
Journal of Parkinson's Disease
vol.
12
,
(
5
)
1605
-
1609
.
Bramich S, King A, Kuruvilla M, Naismith SL, Noyce A, Alty J
(
2022
)
.
Isolated REM sleep behaviour disorder: current diagnostic procedures and emerging new technologies
.
Journal of Neurology
vol.
269
,
(
9
)
4684
-
4695
.
Liu H, Dehestani M, Blauwendraat C, Makarious MB, Leonard H, Kim JJ, Schulte C, Noyce A et al.
(
2022
)
.
Polygenic Resilience Modulates the Penetrance of Parkinson Disease Genetic Risk Factors
.
Annals of Neurology
vol.
92
,
(
2
)
270
-
278
.
Foote IF, Jacobs BM, Mathlin G, Watson CJ, Bothongo PL, Waters S, Dobson R, Noyce AJ et al.
(
2022
)
.
The shared genetic architecture of modifiable risk for Alzheimer's disease: a genomic structural equation modelling study
.
Neurobiology of Aging
vol.
117
,
222
-
235
.
Hone L, Jacobs BM, Marshall C, Giovannoni G, Noyce A, Dobson R
(
2022
)
.
Age-specific effects of childhood body mass index on multiple sclerosis risk
.
Journal of Neurology
vol.
269
,
(
9
)
5052
-
5060
.
Simonet C, Bestwick J, Jitlal M, Waters S, Ben-Joseph A, Marshall CR, Dobson R, Marrium S et al.
(
2022
)
.
Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population
.
JAMA Neurology
vol.
79
,
(
4
)
359
-
369
.
Marshall CR, Noyce AJ, Neligan A, Dobson R
(
2022
)
.
Brain health: The hidden casualty of a humanitarian crisis
.
The Lancet Regional Health - Europe
vol.
15
,
Noyce A
(
2022
)
.
No evidence for association between polygenic risk of Multiple Sclerosis and MRI phenotypes in ~30,000 healthy adult UK Biobank participants
.
Multiple Sclerosis Journal
Noyce A
(
2022
)
.
Assessment of Risk Factors and Early Presentations of Parkinson Disease in Primary Care in a Diverse UK Population
.
JAMA Neurology
Cornejo‐Olivas M, Wu L, Noyce A
(
2022
)
.
Disruption of Mitochondrial Complex I Induces Progressive Parkinsonism
.
Movement Disorders
vol.
37
,
(
3
)
478
-
478
.
Bothongo PLK, Jitlal M, Parry E, Waters S, Foote IF, Watson CJ, Cuzick J, Giovannoni G et al.
(
2022
)
.
Dementia risk in a diverse population: A single-region nested case-control study in the East End of London
.
The Lancet Regional Health - Europe
vol.
15
,
Noyce A
(
2022
)
.
Surveying global availability of Parkinson’s disease treatment
.
Journal of Parkinson's Disease
Noyce A
(
2022
)
.
The potential utility of smell testing to screen for neurodegenerative disorders
.
Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare
Dobson R, Marshall C, Noyce A
(
2022
)
.
Social determinants of neurological disease: tackling inequalities
.
The Lancet Neurology
vol.
21
,
(
2
)
122
-
123
.
Noyce A
(
2022
)
.
Developing and Assessing a New Web-based Tapping Test for Measuring Distal Movement in Parkinson’s Disease: a Distal Finger Tapping Test
.
Scientific Reports
Mitchell E, Chohan H, Bestwick JP, Noyce AJ
(
2022
)
.
Alcohol and Parkinson’s Disease: A Systematic Review and Meta-Analysis
.
Journal of Parkinson's Disease
vol.
12
,
(
8
)
2369
-
2381
.
Chohan H, Simonet C, Gill A, Schrag A, Noyce A, Perez-Carbonell L
(
2022
)
.
What, when and how should the information on iRBD and risk of Parkinson's disease and related conditions be communicated?
.
MOVEMENT DISORDERS
.
vol.
37
,
S622
-
S622
.
Storm CS, Kia DA, Almramhi MM, Bandres-Ciga S, Finan C, Hingorani AD, Wood NW
(
2021
)
.
Finding genetically-supported drug targets for Parkinson’s disease using Mendelian randomization of the druggable genome
.
Nature Communications
vol.
12
,
(
1
)
Bestwick JP, Auger SD, Simonet C, Rees RN, Rack D, Jitlal M, Giovannoni G, Lees AJ et al.
(
2021
)
.
Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm
.
npj Parkinson's Disease
vol.
7
,
(
1
)
Huxford B, Haque T, Joseph AB, Simonet C, Gallagher D, Budu C, Dobson R, Noyce A
(
2021
)
.
Parkinson's Disease and Type 2 Diabetes: HbA1c Is Associated with Motor and Cognitive Severity
.
Movement Disorders
vol.
37
,
(
2
)
427
-
428
.
Heilbron K, Jensen MP, Bandres-Ciga S, Fontanillas P, Blauwendraat C, Nalls MA, Singleton AB, Smith GD et al.
(
2021
)
.
Unhealthy Behaviours and Risk of Parkinson’s Disease: A Mendelian Randomisation Study
.
Journal of Parkinson's Disease
vol.
11
,
(
4
)
1981
-
1993
.
Bestwick J, Auger S, Schrag A, Grosset DG, Kanavou S, Giovannoni G, Lees AJ, Cuzick J et al.
(
2021
)
.
Optimising classification of Parkinson’s disease based on motor, olfactory, neuropsychiatric and sleep features
.
npj Parkinson's Disease
Hone L, Jacobs BM, Marshall C, Giovannoni G, Noyce A, Dobson R
(
2021
)
.
Age-specific effects of childhood Body Mass Index on multiple sclerosis risk
.
Noyce A, Beccano-Kelly D, Bandres-Ciga S, Schumacher Schuh A, Zenebe Y, Siddiqi B
(
2021
)
.
Tackling underrepresentation to aid understanding of Parkinson’s disease: Progress and further opportunities
.
Physiology News
(
Autumn 123
)
Simonet C, Noyce AJ
(
2021
)
.
Domotics, Smart Homes, and Parkinson’s Disease
.
Journal of Parkinson's Disease
vol.
11
,
(
s1
)
s55
-
s63
.
Simonet C, Noyce A
(
2021
)
.
Mild parkinsonian signs: the interface between aging and Parkinson’s disease
.
Advances in Clinical Neuroscience & Rehabilitation
vol.
20
,
Gialluisi A, Reccia MG, Modugno N, Nutile T, Lombardi A, Di Giovannantonio LG, Pietracupa S, Ruggiero D et al.
(
2021
)
.
Identification of sixteen novel candidate genes for late onset Parkinson’s disease
.
Molecular Neurodegeneration
vol.
16
,
(
1
)
Jacobs BM, Noyce AJ, Bestwick J, Belete D, Giovannoni G, Dobson R
(
2021
)
.
Gene-Environment Interactions in Multiple Sclerosis: A UK Biobank Study
.
Neurology Neuroimmunology & Neuroinflammation
vol.
8
,
(
4
)
Blauwendraat C, Iwaki H, Makarious MB, Bandres‐Ciga S, Leonard HL, Grenn FP, Lake J, Krohn L et al.
(
2021
)
.
Investigation of Autosomal Genetic Sex Differences in Parkinson's Disease
.
Annals of Neurology
vol.
90
,
(
1
)
35
-
42
.
Estiar MA, Senkevich K, Yu E, Varghaei P, Krohn L, Bandres‐Ciga S, Noyce AJ, Rouleau GA et al.
(
2021
)
.
Lack of Causal Effects or Genetic Correlation between Restless Legs Syndrome and Parkinson's Disease
.
Movement Disorders
vol.
36
,
(
8
)
1967
-
1972
.
Bandres-Ciga S, Saez-Atienzar S, Kim JJ, Makarious MB, Faghri F, Diez-Fairen M, Iwaki H, Leonard H et al.
(
2021
)
.
Correction to: Large‑scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease
.
Acta Neuropathologica
vol.
142
,
(
1
)
223
-
224
.
Ismail AS, Goodwin GR, Castrejon-Pita JR, Noyce AJ, Azevedo HS
(
2021
)
.
A novel capsule-based smell test fabricated via coaxial dripping
.
Journal of The Royal Society Interface
vol.
18
,
(
177
)
Article
rsif.2021.0039
,
Chen Z, Zhang D, Reynolds RH, Gustavsson EK, García-Ruiz S, D’Sa K, Fairbrother-Browne A, Vandrovcova J et al.
(
2021
)
.
Human-lineage-specific genomic elements are associated with neurodegenerative disease and APOE transcript usage
.
Nature Communications
vol.
12
,
(
1
)
Bestwick JP, Auger SD, Simonet C, Rees RN, Rack D, Jitlal M, Giovannoni G, Lees AJ et al.
(
2021
)
.
Improving estimation of Parkinson’s disease risk—the enhanced PREDICT-PD algorithm
.
npj Parkinson's Disease
vol.
7
,
(
1
)
Jitlal M, Amirthalingam G, Karania T, Parry E, Neligan A, Dobson R, Noyce A, MARSHALL C
(
2021
)
.
The influence of socioeconomic deprivation on dementia mortality, age at death and quality of diagnosis: a nationwide death records study in England and Wales 2001-2017
.
Journal of Alzheimer's Disease
Chohan H, Senkevich K, Patel RK, Bestwick JP, Jacobs BM, Ciga SB, Gan‐Or Z, Noyce AJ
(
2021
)
.
Type 2 Diabetes as a Determinant of Parkinson's Disease Risk and Progression
.
Movement Disorders
vol.
36
,
(
6
)
1420
-
1429
.
Foote IF, Jacobs BM, Mathlin G, Watson CJ, Bothongo PL, Waters S, Dobson R, Noyce AJ et al.
(
2021
)
.
The Genetic Architecture of Alzheimer’s Disease Risk: A Genomic Structural Equation Modelling Study
.
Jensen MP, Jacobs BM, Dobson R, Bandres‐Ciga S, Blauwendraat C, Schrag A, Noyce AJ, Consortium TIPDG
(
2021
)
.
Lower Lymphocyte Count is Associated With Increased Risk of Parkinson's Disease
.
Annals of Neurology
vol.
89
,
(
4
)
803
-
812
.
Kang X, Ploner A, Pedersen N, Bandres-Ciga S, Noyce A, Wirdefeldt K, Williams DM
(
2021
)
.
Tumor Necrosis Factor Inhibition and Parkinson Disease: A Mendelian Randomization Study
.
Neurology
Noyce A
(
2021
)
.
Infection and Risk of Parkinson’s disease
.
Journal of Parkinson's Disease
Program TGPG
(
2021
)
.
GP2: The Global Parkinson's Genetics Program
.
Movement Disorders
vol.
36
,
(
4
)
842
-
851
.
Hone L, Jacobs B, Noyce A, Dobson R
(
2021
)
.
Age-specific effects of childhood BMI on multiple sclerosis risk: a Mendelian Randomisation study
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
27
,
764
-
765
.
Senkevich K, Bandres-Ciga S, Yu E, Liyanage UE, Noyce AJ, Gan-Or Z
(
2021
)
.
No Evidence for a Causal Relationship Between Cancers and Parkinson's Disease
.
Journal of Parkinson's Disease
vol.
11
,
(
2
)
801
-
809
.
Simonet C, Galmes MA, Lambert C, Rees RN, Haque T, Bestwick JP, Lees AJ, Schrag A et al.
(
2021
)
.
Slow Motion Analysis of Repetitive Tapping (SMART) Test: Measuring Bradykinesia in Recently Diagnosed Parkinson’s Disease and Idiopathic Anosmia
.
Journal of Parkinson's Disease
vol.
11
,
(
4
)
1901
-
1915
.
Blauwendraat C, Makarious MB, Leonard HL, Bandres-Ciga S, Iwaki MA, Nalls M, Noyce A, Singleton AB
(
2020
)
.
A population scale analysis of rare SNCA variation in the UK Biobank
.
Neurobiology of Disease
Jacobs BM, Smets I, Giovannoni G, Noyce A, Jokubaitis V, Dobson R
(
2020
)
.
Regarding: Nicotinic acetylcholine receptors α7 and α9 modify tobacco smoke risk for multiple sclerosis
.
Multiple Sclerosis Journal
vol.
27
,
(
8
)
1311
-
1312
.
Foote IF, Jacobs BM, Noyce AJ, Korszun A, Bhui KS, Marshall CR
(
2020
)
.
Exploring the shared genetic architecture of modifiable risk factors and related endophenotypes of Alzheimer’s disease: A genomic SEM study
.
Alzheimer's & Dementia
vol.
16
,
(
S2
)
Noyce AJ, Klein C
(
2020
)
.
Genetic Risk of Alzheimer's Disease – Sleepless with the Enemy
.
Annals of Neurology
vol.
89
,
(
1
)
27
-
29
.
Iwaki H, Blauwendraat C, Leonard HL, Makarious MB, Kim JJ, Liu G, Maple-Grødem J, Corvol JC et al.
(
2020
)
.
Differences in the Presentation and Progression of Parkinson's Disease by Sex
.
Movement Disorders
Auger SD, Jacobs BM, Dobson R, Marshall CR, Noyce AJ
(
2020
)
.
Big data, machine learning and artificial intelligence: a neurologist’s guide
.
Practical Neurology
vol.
21
,
(
1
)
4
-
11
.
Auger S, Jacobs B, Dobson R, MARSHALL C, Noyce A
(
2020
)
.
Navigating a world of big data, machine learning and artificial intelligence: a neurologist's guide
.
Practical Neurology
Jacobs B, Belete D, Bestwick J, Blauwendraat C, Bandres-Ciga S, Heilbron K, Dobson R, International Parkinson’s Disease Genomics Consortium (IPDGC) et al.
(
2020
)
.
Parkinson’s disease determinants, prediction and gene-environment interactions in the UK Biobank
.
Journal of Neurology, Neurosurgery and Psychiatry
vol.
91
,
1046
-
1054
.
Cheong J, Goh Z, Marras C, Tanner C, Kasten M, Noyce A, Movement Disorders Society Epidemiology Study Group
(
2020
)
.
The impact of COVID-19 on access to Parkinson’s disease medication
.
Movement Disorders
Noyce A
(
2020
)
.
Evaluating lipid-lowering drug targets for Parkinson’s disease prevention with Mendelian randomization
.
Annals of Neurology
Mencacci NE, Reynolds R, Ruiz SG, Vandrovcova J, Forabosco P, Sánchez-Ferrer A, Volpato V, Botía JA et al.
(
2020
)
.
Dystonia genes functionally converge in specific neurons and share neurobiology with psychiatric disorders
.
Brain
vol.
143
,
(
9
)
2771
-
2787
.
Jacobs B, Taylor T, Awad A, Baker D, Giovannoni G, Noyce A, Dobson R
(
2020
)
.
Summary-data-based mendelian randomisation prioritises potential druggable targets for Multiple Sclerosis
.
Brain Communications
Akram N, Li H, Ben-Joseph A, Budu C, Gallagher D, Bestwick JP, Noyce AJ, Simonet C
(
2020
)
.
Developing and Validating a New Web-Based Tapping Test for Measuring Distal Bradykinesia in Parkinson’s Disease
.
Noyce A
(
2020
)
.
Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease
.
Acta Neuropathologica
Marini K, Mahlknecht P, Tutzer F, Stockner H, Gasperi A, Djamshidian A, Willeit P, Kiechl S et al.
(
2020
)
.
Application of a Simple Parkinson's Disease Risk Score in a Longitudinal Population‐Based Cohort
.
Movement Disorders
Article
mds.28127
,
Williams DM, Bandres-Ciga S, Heilbron K, Team TAR, Consortium TIPDG, Hinds D, Noyce AJ
(
2020
)
.
Evaluating lipid-lowering drug targets for Parkinson disease prevention with Mendelian randomization
.
Cheong J, de Pablo-Fernandez E, Foltynie T, Noyce A
(
2020
)
.
The association between type 2 diabetes mellitus and Parkinson’s disease
.
Journal of Parkinson's Disease
Iwaki H, Blauwendraat C, Leonard HL, Makarious MB, Kim JJ, Liu G, Maple-Grødem J, Corvol J-C et al.
(
2020
)
.
Differences in the presentation and progression of Parkinson’s disease by sex
.
Bestwick JP, Auger SD, Simonet C, Rees RN, Rack D, Jitlal M, Giovannoni G, Lees AJ et al.
(
2020
)
.
Improving estimation of Parkinson’s disease risk - The enhanced PREDICT-PD algorithm
.
Auger S, Noyce A
(
2020
)
.
Testing shortened versions of smell tests to screen for hyposmia in Parkinson’s disease
.
Movement Disorders Clinical Practice
Guelfi S, D’Sa K, Botía JA, Vandrovcova J, Reynolds RH, Zhang D, Trabzuni D, Collado-Torres L et al.
(
2020
)
.
Regulatory sites for splicing in human basal ganglia are enriched for disease-relevant information
.
Nature Communications
vol.
11
,
(
1
)
(
2020
)
.
Corrigendum
.
Brain
vol.
143
,
(
4
)
e33
-
e33
.
Dobson R, Jitlal M, Marshall CR, Noyce AJ, Robson J, Cuzick J, Giovannoni G
(
2020
)
.
Ethnic and Socioeconomic Associations with Multiple Sclerosis Risk
.
Annals of Neurology
vol.
87
,
(
4
)
599
-
608
.
Dobson R, Noyce A, Giovannoni G, jacobs B
(
2020
)
.
BMI and low serum vitamin D are causal risk factors for Multiple Sclerosis: a Mendelian Randomisation study
.
Neurology, Neuroimmunology and Neuroinflammation
Alarcón F, Maldonado J-C, Cañizares M, Molina J, Noyce AJ, Lees AJ
(
2020
)
.
Motor Dysfunction as a Prodrome of Parkinson’s Disease
.
Journal of Parkinson's Disease
vol.
10
,
(
3
)
1067
-
1073
.
Noyce A, Giovannoni G, Scheltens P, Berg D, Brown L, Dierickx K, Frisoni GB, Georges J et al.
(
2020
)
.
Time matters in brain health: how should society prepare for a growing population at risk of neurodegenerative diseases?
.
EUROPEAN JOURNAL OF NEUROLOGY
.
vol.
27
,
143
-
143
.
Noyce A, Ben-Joseph A, MARSHALL C, Lees A
(
2019
)
.
Ethnic variation in the manifestation of Parkinson’s disease: a narrative review
.
Journal of Parkinson's Disease
Simonet C, Schrag A, Lees AJ, Noyce AJ
(
2019
)
.
The motor prodromes of parkinson’s disease: from bedside observation to large-scale application
.
Journal of Neurology
vol.
268
,
(
6
)
2099
-
2108
.
Nalls MA, Blauwendraat C, Vallerga CL, Heilbron K, Bandres-Ciga S, Chang D, Tan M, Kia DA et al.
(
2019
)
.
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
.
The Lancet Neurology
vol.
18
,
(
12
)
1091
-
1102
.
Noyce A, International Parkinson’s Disease Genomics Consortium (IPDGC)
(
2019
)
.
Genetic modifiers of risk and age at onset in GBA associated Parkinson’s disease and Lewy body dementia
.
Brain: a journal of neurology
Bandres‐Ciga S, Ahmed S, Sabir MS, Blauwendraat C, Adarmes‐Gómez AD, Bernal‐Bernal I, Bonilla‐Toribio M, Buiza‐Rueda D et al.
(
2019
)
.
The Genetic Architecture of Parkinson Disease in Spain: Characterizing Population‐Specific Risk, Differential Haplotype Structures, and Providing Etiologic Insight
.
Movement Disorders
vol.
34
,
(
12
)
1851
-
1863
.
Noyce AJ, Bandres‐Ciga S, Kim J, Heilbron K, Kia D, Hemani G, Xue A, Lawlor DA et al.
(
2019
)
.
The Parkinson's Disease Mendelian Randomization Research Portal
.
Movement Disorders
vol.
34
,
(
12
)
1864
-
1872
.
Bandres-Ciga S, Noyce A, Traynor BJ
(
2019
)
.
Mendelian randomization: a journey from obscurity to center stage with a few potholes along the way
.
JAMA Neurology
vol.
77
,
(
7
)
7
-
8
.
Noyce A, Iwaki H
(
2019
)
.
Genomewide association study of Parkinson's disease clinical biomarkers in 12 longitudinal patients' cohorts
.
Movement Disorders
Neligan A, Noyce AJ, Gosavi TD, Shorvon SD, Köhler S, Walker MC
(
2019
)
.
Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time
.
JAMA Neurology
vol.
76
,
(
8
)
897
-
897
.
Iwaki H, Blauwendraat C, Leonard HL, Liu G, Maple-Grødem J, Corvol J-C, Pihlstrøm L, van Nimwegen M et al.
(
2019
)
.
Genetic risk of Parkinson disease and progression:: An analysis of 13 longitudinal cohorts
.
Neurology Genetics
vol.
5
,
(
4
)
Hasan H, Burrows M, Athauda DS, Hellman B, James B, Warner T, Foltynie T, Giovannoni G et al.
(
2019
)
.
The BRadykinesia Akinesia INcoordination (BRAIN) Tap Test: Capturing the Sequence Effect
.
Movement Disorders Clinical Practice
vol.
6
,
(
6
)
462
-
469
.
Fernández‐Santiago R, Martín‐Flores N, Antonelli F, Cerquera C, Moreno V, Bandres‐Ciga S, Manduchi E, Tolosa E et al.
(
2019
)
.
SNCA and mTOR Pathway Single Nucleotide Polymorphisms Interact to Modulate the Age at Onset of Parkinson's Disease
.
Movement Disorders
vol.
34
,
(
9
)
1333
-
1344
.
NOYCE AJ, Neligan A, Gosavi T, Shorvon S, Köhler S, Walker M
(
2019
)
.
Change in Mortality of Generalized Convulsive Status Epilepticus in High-Income Countries Over Time
A Systematic Review and Meta-analysis
.
JAMA Neurology
Billingsley KJ, Barbosa IA, Bandrés-Ciga S, Quinn JP, Bubb VJ, Deshpande C, Botia JA, Reynolds RH et al.
(
2019
)
.
Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset
.
npj Parkinson's Disease
vol.
5
,
(
1
)
Joseph T, Auger SD, Peress L, Rack D, Cuzick J, Giovannoni G, Lees A, Schrag AE et al.
(
2019
)
.
Screening performance of abbreviated versions of the UPSIT smell test
.
Journal of Neurology
vol.
266
,
(
8
)
1897
-
1906
.
Reynolds RH, Botía J, Nalls MA, Hardy J, Gagliano Taliun SA, Ryten M
(
2019
)
.
Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability
.
npj Parkinson's Disease
vol.
5
,
(
1
)
NOYCE AJ, International Parkinson's Disease Genomics Consortium (IPDGC)
(
2019
)
.
Parkinson's disease age at onset genome-wide association study: Defining heritability, genetic loci, and α-synuclein mechanisms
.
Movement Disorders
Heilbron K, NOYCE AJ, Fontanillas P, Alipanahi B, Nalls MA, 23andMe Research Team, Cannon P
(
2019
)
.
The Parkinson’s Phenome—Traits Associated with Parkinson's Disease in a Broadly Phenotyped Cohort
.
npj Parkinson's Disease
vol.
5
,
Article
4 (2019)
,
Schrag A, Anastasiou Z, Ambler G, NOYCE AJ, walters K
(
2019
)
.
Predicting Diagnosis of Parkinson’s disease: A Risk Algorithm based on Primary Care presentations
.
Movement Disorders
NOYCE AJ
(
2019
)
.
Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis
.
Annals of Neurology
Bandres‐Ciga S, Saez‐Atienzar S, Bonet‐Ponce L, Billingsley K, Vitale D, Blauwendraat C, Gibbs JR, Pihlstrøm L et al.
(
2019
)
.
The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease
.
Movement Disorders
vol.
34
,
(
4
)
460
-
468
.
NOYCE AJ, Rees R, Schrag A
(
2018
)
.
The prodromes of Parkinson's disease
.
European Journal of Neuroscience
Kia DA, Sabir MS, Ahmed S, Trinh J, Bandres-Ciga S, Consortium IPDG, Noyce AJ, Kaiyrzhanov R et al.
(
2018
)
.
LRP10 in α-synucleinopathies
.
The Lancet Neurology
vol.
17
,
(
12
)
Acharya A, Basnett I, Gutteridge C, Noyce A
(
2018
)
.
Laughter isn't always the best medicine
.
BMJ
vol.
363
,
k4579
-
k4579
.
Blauwendraat C, Reed X, Kia DA, Gan-Or Z, Lesage S, Pihlstrøm L, Guerreiro R, Gibbs JR et al.
(
2018
)
.
Frequency of Loss of Function Variants in LRRK2 in Parkinson Disease
.
JAMA Neurology
vol.
75
,
(
11
)
1416
-
1422
.
Rees RN, Acharya AP, Schrag A, Noyce AJ
(
2018
)
.
An early diagnosis is not the same as a timely diagnosis of Parkinson's disease
.
F1000Research
vol.
7
,
1106
-
1106
.
NOYCE AJ
(
2018
)
.
Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson’s disease
.
Annals of Neurology
De Pablo-Fernandez E, Goldacre R, Pakpoor J, Noyce AJ, Warner TT
(
2018
)
.
Association between diabetes and subsequent Parkinson disease
.
Neurology
vol.
91
,
(
2
)
e139
-
e142
.
Noyce A
(
2018
)
.
Remembering the man behind An Essay on the Shaking Palsy
.
The Lancet Neurology
vol.
17
,
(
6
)
Keddie S, Adams A, Kelso ARC, Turner B, Schmierer K, Gnanapavan S, Malaspina A, Giovannoni G et al.
(
2018
)
.
No laughing matter: subacute degeneration of the spinal cord due to nitrous oxide inhalation
.
Journal of Neurology
vol.
265
,
(
5
)
1089
-
1095
.
Weil RS, Schwarzkopf DS, Bahrami B, Fleming SM, Jackson BM, Goch TJC, Saygin AP, Miller LE et al.
(
2018
)
.
Assessing cognitive dysfunction in Parkinson's disease: An online tool to detect visuo‐perceptual deficits
.
Movement Disorders
vol.
33
,
(
4
)
544
-
553
.
NOYCE AJ
(
2018
)
.
Assessing cognitive dysfunction in Parkinson’s: An online tool to detect visuo-perceptual deficits
.
Movement Disorders
Noyce AJ, Dickson J, Rees RN, Bestwick JP, Isaias IU, Politis M, Giovannoni G, Warner TT et al.
(
2018
)
.
Dopamine reuptake transporter–single‐photon emission computed tomography and transcranial sonography as imaging markers of prediagnostic Parkinson's disease
.
Movement Disorders
vol.
33
,
(
3
)
478
-
482
.
Blauwendraat C, Kia DA, Pihlstrøm L, Gan-Or Z, Lesage S, Gibbs JR, Ding J, Alcalay RN et al.
(
2017
)
.
Insufficient evidence for pathogenicity of SNCA His50Gln (H50Q) in Parkinson's disease
.
Neurobiology of Aging
vol.
64
,
159.e5
-
159.e8
.
Shribman S, Noyce A, Gnanapavan S, Lambourne J, Harrison T, Schon F
(
2017
)
.
Cryptococcal meningitis in apparently immunocompetent patients: association with idiopathic CD4+ lymphopenia
.
Practical Neurology
vol.
18
,
(
2
)
Shribman S, Hasan H, Hadavi S, Giovannoni G, Noyce AJ
(
2017
)
.
The BRAIN test: a keyboard-tapping test to assess disability and clinical features of multiple sclerosis
.
Journal of Neurology
vol.
265
,
(
2
)
285
-
290
.
Noyce AJ, Lees A
(
2017
)
.
Observations on a 2-Step Approach to Screening for Parkinson Disease
.
JAMA Neurology
vol.
74
,
(
12
)
1506
-
1506
.
Noyce A, Bandopadhyay R
(
2017
)
.
Parkinson's Disease: Basic Pathomechanisms and a Clinical Overview
.
vol.
15
,
Raciborska DD, Noyce AJ, Pyne D, Turner BP
(
2017
)
.
Lupus myelopathy
.
Practical Neurologypractneurol-2017-001
-
practneurol-2017-001
.
Lynch DS, Loh SHY, Harley J, Noyce AJ, Martins LM, Wood NW, Houlden H, Plun-Favreau H
(
2017
)
.
Nonsyndromic Parkinson disease in a family with autosomal dominant optic atrophy due to OPA1 mutations
.
Neurology Genetics
vol.
3
,
(
5
)
e188
-
e188
.
Noyce AJ, Kia DA, Hemani G, Nicolas A, Price TR, De Pablo-Fernandez E, Haycock PC, Lewis PA et al.
(
2017
)
.
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study
.
PLOS Medicine
vol.
14
,
(
6
)
e1002314
-
e1002314
.
Noyce A, Kia D, Hemani G, Nicolas A, Price T, Fernandez E, Haycock P, Lewis P et al.
(
2017
)
.
Increased BMI May Protect against Parkinson's Disease: Evidence From Mendelian Randomisation Study
.
vol.
32
,
Abstract:
java.sql.Clob
org.hibernate.engine.jdbc.WrappedClob
java.io.Serializable
,
Magdalinou NK, Noyce AJ, Pinto R, Lindstrom E, Holmen-Larsson J, Holtta M, Blennow K, Morris HR et al.
(
2017
)
.
Identification of candidate cerebrospinal fluid biomarkers in parkinsonism using quantitative proteomics
.
PARKINSONISM & RELATED DISORDERS
vol.
37
,
65
-
71
.
Pakpoor J, Noyce A, Goldacre R, Selkihova M, Mullin S, Schrag A, Lees A, Goldacre M
(
2017
)
.
Viral hepatitis and Parkinson disease
.
Neurology
vol.
88
,
(
17
)
1630
-
1633
.
Noyce AJ, Schrag A, Masters JM, Bestwick JP, Giovannoni G, Lees AJ
(
2017
)
.
Subtle motor disturbances in PREDICT-PD participants
.
J Neurol Neurosurg Psychiatry
vol.
88
,
(
3
)
212
-
217
.
Hasan H, Athauda DS, Foltynie T, Noyce AJ
(
2017
)
.
Technologies Assessing Limb Bradykinesia in Parkinson’s Disease
.
Journal of Parkinson's Disease
vol.
7
,
(
1
)
65
-
77
.
Noyce AJ, R'Bibo L, Peress L, Bestwick JP, Adams-Carr KL, Mencacci NE, Hawkes CH, Masters JM et al.
(
2017
)
.
PREDICT-PD: An online approach to prospectively identify risk indicators of Parkinson's disease
.
Mov Disord
vol.
32
,
(
2
)
219
-
226
.
Noyce A, Dickson J, Bestwick J, Isaias I, Politis M, Giovannoni G, Warner T, Lees A et al.
(
2017
)
.
Associations of DAT SPECT and TCS with prodromal features of Parkinson's disease: Results in PREDICT-PD participants
.
MOVEMENT DISORDERS
.
vol.
32
,
Nagy A, Hardaker E, Bestwick J, Giovannoni G, Warner T, Lees A, Schrag A, Noyce A
(
2017
)
.
Cognition in the PREDICT-PD Cohort
.
MOVEMENT DISORDERS
.
vol.
32
,
Lubbe SJ, Escott-Price V, Gibbs JR, Nalls MA, Bras J, Price TR, Nicolas A, Jansen IE et al.
(
2016
)
.
Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritance
.
Human Molecular Genetics
vol.
24
,
ddw348
-
ddw348
.
Adams-Carr KL, Bestwick JP, Shribman S, Lees A, Schrag A, Noyce AJ
(
2016
)
.
Constipation preceding Parkinson's disease: a systematic review and meta-analysis
.
J Neurol Neurosurg Psychiatry
vol.
87
,
(
7
)
710
-
716
.
Hasan H, Athauda DS, Foltynie T, Giovannoni G, Warner T, Lees AJ, Noyce A
(
2016
)
.
Objective decrement in Parkinson's disease - A new parameter for the BRAIN tap test
.
Movement Disorders
.
Conference:
20th International Congress of Parkinson's Disease and Movement Disorders
(
Berlin, Germany
)
from:
19/06/2016
to:
23/06/2016
,
vol.
31
,
S177
-
S177
.
Salat D, Noyce AJ, Schrag A, Tolosa E
(
2016
)
.
Challenges of modifying disease progression in prediagnostic Parkinson's disease
.
The Lancet Neurology
vol.
15
,
(
6
)
637
-
648
.
Mok KY, Sheerin U, Simón-Sánchez J, Salaka A, Chester L, Escott-Price V, Mantripragada K, Doherty KM et al.
(
2016
)
.
Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data
.
The Lancet Neurology
vol.
15
,
(
6
)
585
-
596
.
Noyce AJ, Lees AJ, Schrag A-E
(
2016
)
.
The prediagnostic phase of Parkinson's disease
.
Journal of Neurology, Neurosurgery & Psychiatry
vol.
87
,
(
8
)
871
-
878
.
Masters JM, Noyce AJ, Lynham S, Warner TT, Giovannoni G, Proctor GB
(
2016
)
.
A comprehensive characterisation of the salivary proteome of patients with Parkinson's disease
.
MOVEMENT DISORDERS
.
vol.
31
,
S238
-
S239
.
Noyce AJ, Schrag A, Masters J, Bestwick JP, Giovannoni G, Lees AJ
(
2016
)
.
Blinded video assessment of subtle Parkinsonian signs in PREDICT-PD participants
.
MOVEMENT DISORDERS
.
vol.
31
,
S506
-
S506
.
Mok KY, Sheerin U, Simon-Sanchez J, Salaka A, Chester L, Escott-Price V, Mantripragada K, Doherty KM et al.
(
2016
)
.
Deletions at 22q11.2 in idiopathic Parkinson's disease: A combined analysis of GWAS data
.
MOVEMENT DISORDERS
.
vol.
31
,
S221
-
S222
.
R'Bibo L, Mencacci NE, Schrag A, Bestwick JP, Peress L, Masters J, Giovannoni G, Lees AJ et al.
(
2016
)
.
Exploring association of GBA variants with pre-diagnostic features of PD in the PREDICT-PD cohort: A nested case-control study
.
MOVEMENT DISORDERS
.
vol.
31
,
S125
-
S125
.
Simonet C, Noyce AJ, Ling H, Lees AJ, Warner TT
(
2016
)
.
Handwriting in Parkinson's disease: Systematic review and preliminary study
.
MOVEMENT DISORDERS
.
vol.
31
,
S508
-
S508
.
Osborne CW, Bestwick J, Giovannoni G, Lees AJ, Schrag A, Noyce A
(
2016
)
.
Participant feedback in the PREDICT-PD study
.
MOVEMENT DISORDERS
.
vol.
31
,
S594
-
S594
.
Noyce AJ, Nalls MA
(
2015
)
.
Mendelian Randomization — the Key to Understanding Aspects of Parkinson's Disease Causation?
.
Movement Disorders
vol.
31
,
(
4
)
478
-
483
.
Noyce A, Bestwick J, Mencacci N, Hawkes C, Hardy J, Giovannoni G, Lees A, Schrag A
(
2015
)
.
PREDICT-PD: Identifying Risk of Parkinson's disease in the Community
.
MOVEMENT DISORDERS
.
vol.
30
,
1989
-
1989
.
Masters JM, Bestwick J, Warner TT, Giovannoni G, Proctor GB, Noyce AJ
(
2015
)
.
Systematic review and meta‐analysis of salivary protein concentration in Parkinson's disease
.
Movement Disorders
vol.
30
,
(
14
)
1971
-
1972
.
Adams-Carr K, Schrag A, Shribman S, Bestwick J, Lees A, Noyce A
(
2015
)
.
CONSTIPATION PRECEDING PARKINSON'S DISEASE–META-ANALYSIS
.
Journal of Neurology Neurosurgery & Psychiatry
.
vol.
86
,
Masters J, Noyce A, Giovannoni G, Warner T, Proctor G
(
2015
)
.
ELEVATED SALIVARY DJ-1 IN PARKINSON'S DISEASE IS ASSOCIATED WITH ALTERED SALIVARY SECRETION
.
Journal of Neurology Neurosurgery & Psychiatry
.
vol.
86
,
Nalls MA, McLean CY, Rick J, Eberly S, Hutten SJ, Gwinn K, Sutherland M, Martinez M et al.
(
2015
)
.
Diagnosis of Parkinson's disease on the basis of clinical and genetic classification: a population-based modelling study
.
The Lancet Neurology
vol.
14
,
(
10
)
1002
-
1009
.
Masters JM, Noyce AJ, Warner TT, Giovannoni G, Proctor GB
(
2015
)
.
Elevated salivary protein in Parkinson's disease and salivary DJ-1 as a potential marker of disease severity
.
Parkinsonism & Related Disorders
vol.
21
,
(
10
)
1251
-
1255
.
Noyce AJ, Mencacci NE, Schrag A, Bestwick JP, Giovannoni G, Lees AJ, Hardy J
(
2015
)
.
Web‐based assessment of Parkinson's prodromal markers identifies GBA variants
.
Movement Disorders
vol.
30
,
(
7
)
1002
-
1003
.
Nagy A, Noyce A, Velayos-Baeza A, Lees AJ, Warner TT, Ling H
(
2015
)
.
Late Emergence of Parkinsonian Phenotype and Abnormal Dopamine Transporter Scan in Chorea‐Acanthocytosis
.
Movement Disorders Clinical Practice
vol.
2
,
(
2
)
182
-
186
.
Adams-Carr KL, Schrag A, Shribman S, Bestwick JP, Lees A, Noyce AJ
(
2015
)
.
Constipation preceding Parkinson's disease - Systematic review and meta-analysis
.
MOVEMENT DISORDERS
.
vol.
30
,
S149
-
S149
.
Masters JM, Noyce AJ, Giovannoni G, Warner TT, Proctor GB
(
2015
)
.
Elevated salivary DJ-1 in Parkinson's disease is associated with altered salivary secretion
.
MOVEMENT DISORDERS
.
vol.
30
,
S169
-
S170
.
Athauda DS, Hasan H, Noyce A, Foltynie T
(
2015
)
.
Evaluating the use of the online bradykinesia-akinesia Incoordination (BRAIN) test in Parkinson's disease in "on" and "off" states
.
MOVEMENT DISORDERS
.
vol.
30
,
S414
-
S415
.
Magdalinou N, Ling H, Noyce A, Massey L, Paterson R, Schott J, Davagnanam I, Micallef C et al.
(
2015
)
.
The visual estimation of midbrain to pons ratio combined with cerebrospinal fluid biomarkers improves the diagnostic accuracy of PSP
.
MOVEMENT DISORDERS
.
vol.
30
,
S321
-
S321
.
Schrag A, Horsfall L, Walters K, Noyce A, Petersen I
(
2014
)
.
Prediagnostic presentations of Parkinson's disease in primary care: a case-control study
.
The Lancet Neurology
vol.
14
,
(
1
)
57
-
64
.
Torsney KM, Noyce AJ, Doherty KM, Bestwick JP, Dobson R, Lees AJ
(
2014
)
.
Bone health in Parkinson's disease: a systematic review and meta-analysis
.
J Neurol Neurosurg Psychiatry
vol.
85
,
(
10
)
1159
-
1166
.
Osborne C, Noyce A, Sylvester R
(
2014
)
.
AUTO-REGULATION ICP IN IIH DUE TO CHRONIC CSF LEAK
.
Journal of Neurology Neurosurgery & Psychiatry
.
vol.
85
,
e4
-
e4
.
Mencacci NE, Isaias IU, Reich MM, Ganos C, Plagnol V, Polke JM, Bras J, Hersheson J et al.
(
2014
)
.
Parkinson's disease in GTP cyclohydrolase 1 mutation carriers
.
Brain
vol.
137
,
(
Pt 9
)
2480
-
2492
.
Staff TPO
(
2014
)
.
Correction: Bradykinesia-Akinesia Incoordination Test: Validating an Online Keyboard Test of Upper Limb Function
.
PLOS ONE
vol.
9
,
(
8
)
Osborne C, Stallworthy S, Evanson J, Sylvester R, Noyce AJ
(
2014
)
.
Rapid-onset flaccid paraplegia caused by multiple myeloma dumbbell tumour
.
Pract Neurol
vol.
14
,
(
4
)
268
-
269
.
Shribman S, Torsney KM, Noyce AJ, Giovannoni G, Fearnley J, Dobson R
(
2014
)
.
A service development study of the assessment and management of fracture risk in Parkinson's disease
.
J Neurol
vol.
261
,
(
6
)
1153
-
1159
.
Shribman SE, Torsney K, Noyce AJ, Giovannoni G, Fearnley J, Dobson R
(
2014
)
.
A service development study of the assessment and management of fracture risk in Parkinson's disease
.
MOVEMENT DISORDERS
.
vol.
29
,
S192
-
S192
.
Torsney KM, Noyce AJ, Doherty KM, Bestwick JP, Dobson R, Lees AJ
(
2014
)
.
A systematic review and meta-analysis of fracture risk in Parkinson's disease
.
MOVEMENT DISORDERS
.
vol.
29
,
S551
-
S551
.
Torsney KM, Noyce AJ, Doherty KM, Bestwick JP, Dobson R, Lees AJ
(
2014
)
.
Bone health in Parkinson's disease: A systematic review and meta-analysis
.
MOVEMENT DISORDERS
.
vol.
29
,
S551
-
S551
.
Noyce AJ, Nagy A, Acharya S, Hadavi S, Bestwick JP, Fearnley J, Lees AJ, Giovannoni G
(
2014
)
.
Bradykinesia-akinesia incoordination test: validating an online keyboard test of upper limb function
.
PLoS One
vol.
9
,
(
4
)
Noyce AJ, Mencacci N, Schrag A, Giovannoni G, Lees AJ, Hardy J
(
2014
)
.
GBA1 and LRRK2 mutations in higher and lower risk subjects from the PREDICT-PD project
.
MOVEMENT DISORDERS
.
vol.
29
,
S58
-
S59
.
Nalls MA, Saad M, Noyce AJ, Keller MF, Schrag A, Bestwick JP, Traynor BJ, Gibbs JR et al.
(
2014
)
.
Genetic comorbidities in Parkinson's disease
.
HUMAN MOLECULAR GENETICS
vol.
23
,
(
3
)
831
-
841
.
Mencacci NE, Isaias IU, Reich MM, Ganos C, Plagnol V, Polke JM, Bras J, Stamelou M et al.
(
2014
)
.
Parkinson's disease in GTP cyclohydrolase-1 mutation carriers
.
MOVEMENT DISORDERS
.
vol.
29
,
S57
-
S57
.
Shribman SE, Noyce AJ, Martin JE, Giovannoni G, Knowles CH
(
2014
)
.
The distribution of α-synuclein in the enteric nervous system: An immunohistochemical study on colonic resections from 24 control and 4 Parkinson's disease patients
.
MOVEMENT DISORDERS
.
vol.
29
,
1839
-
1839
.
Nagy A, Noyce A, Lees A, Warner T, Ling H
(
2014
)
.
Two cases of abnormal dopamine transporter scan in chorea-acanthocytosis
.
MOVEMENT DISORDERS
.
vol.
29
,
S195
-
S196
.
Hadavi S, Shribman S, Nagy A, Acharya S, Fearnley J, Dobson R, Lees A, Giovannoni G et al.
(
2013
)
.
The bradykinesia-akinesia incoordination test: a simple objective test in multiple sclerosis
.
J Neurol Neurosurg Psychiatry
vol.
84
,
(
11
)
Noyce AJ, Bestwick JP, Silveira-Moriyama L, Hawkes CH, Knowles CH, Hardy J, Giovannoni G, Nageshwaran S et al.
(
2013
)
.
PREDICT-PD: Identifying risk of Parkinson's disease in the community: methods and baseline results
.
Journal of Neurology Neurosurgery & Psychiatry
vol.
85
,
(
1
)
Dobson R, Yarnall A, Noyce AJ, Giovannoni G
(
2013
)
.
Bone health in chronic neurological diseases: a focus on Multiple sclerosis and Parkinsonian syndromes
.
Pract Neurol
vol.
13
,
(
2
)
70
-
79
.
Nagy A, Acharya S, Hadavi S, Bestwick JP, Fearnley J, Lees AJ, Giovannoni G, Noyce AJ
(
2013
)
.
Bradykinesia-akinesia incoordination test: Validating an online keyboard test of upper limb function
.
MOVEMENT DISORDERS
.
vol.
28
,
S114
-
S114
.
Djamshidian A, O'Sullivan SS, Foltynie T, Aviles-Olmos I, Limousin P, Noyce A, Zrinzo L, Lees AJ et al.
(
2013
)
.
Dopamine agonists rather than deep brain stimulation cause reflection impulsivity in Parkinson's disease
.
MOVEMENT DISORDERS
.
vol.
28
,
S130
-
S130
.
Djamshidian A, O'Sullivan SS, Foltynie T, Aviles-Olmos I, Limousin P, Noyce A, Zrinzo L, Lees AJ et al.
(
2013
)
.
Dopamine agonists rather than deep brain stimulation cause reflection impulsivity in Parkinson's disease
.
J Parkinsons Dis
vol.
3
,
(
2
)
139
-
144
.
Noyce AJ, Bestwick JP, Silveira-Moriyama L, Hawkes CH, Knowles C, Hardy J, Giovannoni G, Nageshwaran S et al.
(
2013
)
.
PREDICT-PD study: Online screening algorithm identifying Parkinson's disease risk
.
MOVEMENT DISORDERS
.
vol.
28
,
S389
-
S389
.
Noyce AJ, Bestwick JP, Silveira-Moriyama L, Hawkes CH, Giovannoni G, Lees AJ, Schrag A
(
2012
)
.
Meta-analysis of early nonmotor features and risk factors for Parkinson disease
.
Ann Neurol
vol.
72
,
(
6
)
893
-
901
.
Chan MV, Bubb KJ, Noyce A, Villar IC, Duchene J, Hobbs AJ, Scotland RS, Ahluwalia A
(
2012
)
.
Distinct endothelial pathways underlie sexual dimorphism in vascular auto-regulation
.
Br J Pharmacol
vol.
167
,
(
4
)
805
-
817
.
Noyce AJ, Silveira-Moriyama L, Gilpin P, Ling H, Howard R, Lees AJ
(
2012
)
.
Severe dysphagia as a presentation of Parkinson's disease
.
Mov Disord
vol.
27
,
(
3
)
457
-
458
.
Doherty KM, Silveira-Moriyama L, Nisbet A, Noyce A, Quinn N, Parton M, Lees AJ
(
2012
)
.
0854 Camptocormia: what is the cause?
.
Journal of Neurology Neurosurgery & Psychiatry
.
vol.
83
,
Noyce A, Silveira-Moriyama L, Lees AJ, Schrag A, Bestwick J, Hawkes CH, Giovannoni G, Hardy J et al.
(
2012
)
.
A PILOT STUDY OF AN ALGORITHM DESIGNED TO IDENTIFY PARKINSON'S DISEASE IN THE EARLY, NON-MOTOR PHASE
.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
.
vol.
83
,
Noyce A, Bestwick J, Hawkes CH, Knowles CH, Hardy J, Lees AJ, Silveira-Moriyama L, Giovannoni G et al.
(
2012
)
.
AN ALGORITHM TO IDENTIFY INDIVIDUALS AT HIGH-RISK OF PARKINSON'S DISEASE IN THE COMMUNITY
.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
.
vol.
83
,
Noyce AJ, Bestwick J, Silveira-Moriyama L, Hawkes CH, Giovannoni G, Lees AJ, Schrag A
(
2012
)
.
Risk factors and early non-motor features for Parkinson's disease: A systematic review and meta-analysis
.
MOVEMENT DISORDERS
.
vol.
27
,
S4
-
S4
.
Noyce A, Treacy C, Budu C, Fearnley J, Lees AJ, Giovannoni G
(
2012
)
.
THE NEW BRADYKINESIA AKINESIA INCOORDINATION (BRAIN) TEST: AN ONLINE TEST OF UPPER LIMB MOVEMENT
.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
.
vol.
83
,
Acharya S, Nagy A, Budu C, Treacy C, Fearnley J, Lees AJ, Giovannoni G, Noyce AJ
(
2012
)
.
The new bradykinesia akinesia incoordination (BRAIN) test: People with Parkinson's disease versus healthy controls
.
MOVEMENT DISORDERS
.
vol.
27
,
S102
-
S102
.
Hadavi S, Noyce AJ, Leslie RD, Giovannoni G
(
2011
)
.
Stiff person syndrome
.
Pract Neurol
vol.
11
,
(
5
)
272
-
282
.
Noyce AJ, Treacy C, Budu C, Fearnley J, Lees AJ, Giovannoni G
(
2011
)
.
The new Bradykinesia Akinesia Incoordination (BRAIN) test: Preliminary data from an online test of upper limb movement
.
Movement Disorders
vol.
27
,
(
1
)
157
-
158
.
Doherty KM, Noyce AJ, Silveira-Moriyama L, Nisbet A, Quinn N, Lees AJ
(
2011
)
.
Familial camptocormia: from dystonia to myopathy
.
Journal of Neurology Neurosurgery & Psychiatry
vol.
83
,
(
3
)
Noyce AJ, Bestwick J, Hawkes CH, Schrag A, Knowles CH, Hardy J, Lees AJ, Giovannoni G et al.
(
2011
)
.
A pilot study of an algorithm designed to identify Parkinson's disease in the early, non-motor phase
.
MOVEMENT DISORDERS
.
vol.
26
,
S54
-
S54
.
Noyce AJ, Bestwick J, Hawkes CH, Knowles CH, Hardy J, Lees AJ, Silveira-Moriyama L, Giovannoni G et al.
(
2011
)
.
An algorithm to identify individuals at high-risk of Parkinson's disease in the community
.
MOVEMENT DISORDERS
.
vol.
26
,
S54
-
S55
.
Hadavi SY, Bahra M, Noyce AJ, Webb A
(
2011
)
.
POTENTIAL FOR SERIOUS UNDER-REPORTING OF PRESCRIBING ERRORS BY NEWLY-QUALIFIED DOCTORS
.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
.
vol.
109
,
159
-
159
.
Noyce AJ, Gilpin P, Howard R, Lees AJ, Silviera-Moriyama L
(
2011
)
.
Severe dysphagia preceding Parkinson's disease
.
MOVEMENT DISORDERS
.
vol.
26
,
S195
-
S196
.
Noyce AJ, McCrae S, Gawler J, Evanson J
(
2010
)
.
Teaching NeuroImages: microhemorrhages resulting from cranial radiotherapy in childhood
.
Neurology
vol.
75
,
(
1
)
e2
-
e3
.
Shah M, Deeb J, Fernando M, Noyce A, Visentin E, Findley LJ, Hawkes CH
(
2009
)
.
Abnormality of taste and smell in Parkinson's disease
.
Parkinsonism Relat Disord
vol.
15
,
(
3
)
232
-
237
.
Shah M, Deeb J, Fernando M, Visentin E, Noyce A, Findley LJ, Hawkes CH
(
2007
)
.
Taste is abnormal in Parkinson disease and suggests cortical spread
.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
.
vol.
78
,
1024
-
1024
.
Noyce AL, Hetley RS, Dobias JJ, Stine WW
(
2007
)
.
Perception of local rigidity due to lines in rotating random-dot textures viewed through an aperture
.
PERCEPTION
.
vol.
36
,
204
-
204
.
Shah M, Deeb J, Fernando M, Visentin E, Noyce A, Findley LJ, Hawkes CH
(
2007
)
.
Taste threshold is abnormal in Parkinson's disease and suggests cortical spread
.
MOVEMENT DISORDERS
.
vol.
22
,
S199
-
S199
.
Shah M, Noyce A, Deeb J, Findley LJ, Hawkes CH
(
2006
)
.
Chemosensory measurement in essential tremor
.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
.
vol.
77
,
1397
-
1397
.
Shah M, Noyce A, Deeb J, Findley LJ, Hawkes CH
(
2006
)
.
Smell identification and taste threshold are normal in essential tremor
.
CHEMICAL SENSES
.
vol.
31
,
E27
-
E27
.
Shah M, Noyce A, Deeb J, Findley LJ, Hawkes CH
(
2006
)
.
Chemosensory measurement in essential tremor
.
EUR J NEUROL
vol.
13
,
212
-
212
.
Noyce A, Shah M, Deeb J, Findley LJ, Hawkes CH
(
2006
)
.
Chemosensory measurement in essential tremor
.
CHEMICAL SENSES
.
vol.
31
,
A30
-
A31
.