Publications: Dr Robert Poston

Poston RN, Chughtai J, Ujkaj D, Louis H, Leake DS, Cooper D ( 2022 ) . Monocytic Cell Adhesion to Oxidised Ligands: Relevance to Cardiovascular Disease . Biomedicines vol. 10 , ( 12 )

Karamanavi E, McVey DG, van der Laan SW, Stanczyk PJ, Morris GE, Wang Y, Yang W, Chan K et al. ( 2022 ) . The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis . Circulation Research vol. 131 , ( 12 ) 1004 - 1017 .

Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen-Woods C, Reglero-Real N, Stein M et al. ( 2021 ) . Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage . Immunity vol. 54 , ( 7 ) 1494 - 1510.e7 .

An W, Luong LA, Bowden NP, Yang M, Wu W, Zhou X, Liu C, Niu K et al. ( 2021 ) . Cezanne is a critical regulator of pathological arterial remodelling by targeting β-catenin signalling . Cardiovascular Research vol. 118 , ( 2 ) 638 - 653 .

Karamanavi E, Mcvey DG, Van Der Laan SW, Yang W, Chan K, Poston RN, Jones PD, Kostogrys RB et al. ( 2020 ) . The FES gene, located at the chromosome 15Q21.6 coronary-artery-disease locus, modulates atherosclerotic plaque vulnerability . Atherosclerosis vol. 315 ,

Heister PM, Poston RN ( 2020 ) . Pharmacological hypothesis: TPC2 antagonist tetrandrine as a potential therapeutic agent for COVID‐19 . Pharmacology Research & Perspectives vol. 8 , ( 5 )

Yang X, Yang W, McVey DG, Zhao G, Hu J, Poston RN, Ren M, Willeit K et al. ( 2020 ) . FURIN Expression in Vascular Endothelial Cells Is Modulated by a Coronary Artery Disease–Associated Genetic Variant and Influences Monocyte Transendothelial Migration . Journal of the American Heart Association vol. 9 , ( 4 )

Read JE, Luo D, Chowdhury TT, Flower RJ, Poston RN, Sukhorukov GB, Gould DJ ( 2020 ) . Magnetically responsive layer-by-layer microcapsules can be retained in cells and under flow conditions to promote local drug release without triggering ROS production . Nanoscale vol. 12 , ( 14 ) 7735 - 7748 .

Arokiasamy S, King R, Boulaghrasse H, Poston R, Nourshargh S, Wang W, Voisin M-B ( 2019 ) . Heparanase-dependent Remodelling of Initial Lymphatic Glycocalyx 1 Regulates Tissue-fluid Drainage during Acute Inflammation in vivo . Frontiers in Immunology

Poston RN ( 2019 ) . Atherosclerosis: integration of its pathogenesis as a self-perpetuating propagating inflammation: a review . Cardiovascular Endocrinology & Metabolism vol. 8 , ( 2 ) 51 - 61 .

Luo D, Poston RN, Gould DJ, Sukhorukov GB ( 2018 ) . Magnetically targetable microcapsules display subtle changes in permeability and drug release in response to a biologically compatible low frequency alternating magnetic field . Materials Science and Engineering C vol. 94 , 647 - 655 .

Tarvala U, Poston RN ( 2018 ) . P31 VARIATION OF VON-WILLEBRAND FACTOR EXPRESSION IN THE ENDOTHELIUM OF HUMAN CORONARY ATHEROSCLEROTIC PLAQUES: IMPLICATIONS FOR THROMBOSIS . Cardiovascular Research . vol. 114 , s10 - s10 .

Tarvala U, Matary RE, Nightingale T, Poston R ( 2018 ) . Decrease in Von-Willebrand factor protein in the endothelium of human coronary atherosclerotic plaques: Possible mechanisms and role in thrombosis . Atherosclerosis . vol. 275 ,

Gai M, Kurochkin MA, Li D, Khlebtsov BN, Dong L, Tarakina N, Poston R, Gould DJ et al. ( 2018 ) . In-situ NIR-laser mediated bioactive substance delivery to single cell for EGFP expression based on biocompatible microchamber-arrays . J Control Release vol. 276 , 84 - 92 .

Tarvala U, Poston RN ( 2018 ) . Variation of von-Willebrand Factor Expression in the Endothelium of Human Coronary Atherosclerotic Plaques: Implications for Thrombosis . JOURNAL OF PATHOLOGY . vol. 246 , S24 - S24 .

Chan K, Pu X, Sandesara P, Poston RN, Simpson IA, Quyyumi AA, Ye S, Patel RS ( 2017 ) . Genetic Variation at the ADAMTS7 Locus is Associated With Reduced Severity of Coronary Artery Disease . Journal of the American Heart Association . vol. 6 ,

Chan K, Patel R, Pu X, Simpson IA, Poston RN, Hayek S, Ye S, Quyyumi A ( 2017 ) . Genetic variation at ADAMTS7 and severity of coronary artery disease . The Lancet . vol. 389 ,

Yang W, Ng FL, Chan K, Pu X, Poston RN, Ren M, An W, Zhang R et al. ( 2016 ) . Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction . PLoS Genetics vol. 12 , ( 7 ) e1006127 - e1006127 .

Nasr H, Torsney E, Poston RN, Hayes L, Gaze DC, Basser R, Thompson MM, Loftus IM et al. ( 2015 ) . Investigating the Effect of a Single Infusion of Reconstituted High-Density Lipoprotein in Patients with Symptomatic Carotid Plaques . Annals of Vascular Surgery vol. 29 , ( 7 ) 1380 - 1391 .

Chan K, Patel R, Pu X, Ng F-L, Simpson IA, Poston RN, Ye S, Quyyumi A et al. ( 2015 ) . 189 Genetic Variation in ADAMTS7 is Associated with Severity of Coronary Artery Disease . Heart . vol. 101 ,

Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C et al. ( 2013 ) . YIA3: ADAMTS7 CLEAVAGE AND VASCULAR SMOOTH MUSCLE CELL MIGRATION IS AFFECTED BY A CORONARY ARTERY DISEASE ASSOCIATED VARIANT . Heart . vol. 99 ,

Pu X, Xiao Q, Kiechl S, Chan K, Ng FL, Gor S, Poston RN, Fang C et al. ( 2013 ) . ADAMTS7 Cleavage and Vascular Smooth Muscle Cell Migration Is Affected by a Coronary-Artery-Disease-Associated Variant . American Journal of Human Genetics vol. 92 , ( 3 ) 366 - 374 .

Motterle A, Pu X, Wood H, Xiao Q, Gor S, Ng FL, Chan K, Cross F et al. ( 2012 ) . Functional analyses of coronary artery disease associated variation on chromosome 9p21 in vascular smooth muscle cells . Human Molecular Genetics vol. 21 , ( 18 ) 4021 - 4029 .

Foster PA, Costa SKP, Poston R, Hoult JRS, Brain SD ( 2003 ) . Endothelial cells play an essential role in the thermal hyperalgesia induced by nerve growth factor . The FASEB Journal vol. 17 , ( 12 ) 1703 - 1705 .