Publications: Dr Alistair Symonds
Symonds ALJ, Busharat Z, Du M, Miao T, Li S, Hou X, Wang P
(
2024
)
.
Memory Phenotype Tfh Cells Develop Without Overt Infection and Support Germinal Center Formation and B Cell Responses to Viral Infection
.
European Journal of Immunology
Wang X, Zha H, Wu W, Yuan T, Xie S, Jin Z, Long H, Yang F et al.
(
2023
)
.
CD200+ cytotoxic T lymphocytes in the tumor microenvironment are crucial for efficacious anti–PD-1/PD-L1 therapy
.
Science Translational Medicine
vol.
15
,
(
679
)
Symonds ALJ, Miao T, Busharat Z, Li S, Wang P
(
2022
)
.
Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells
.
Cancer Immunology, Immunotherapy
vol.
72
,
(
5
)
1139
-
1151
.
Symonds AL, Zheng W, Miao T, Wang H, Wang T, Kiome R, Hou X, Li S et al.
(
2020
)
.
Egr2 and 3 control inflammation, but maintain homeostasis, of PD-1high memory phenotype CD4 T cells
.
Life Science Alliance
vol.
3
,
(
9
)
Zhou J, Huang S, Wang Z, Huang J, Xu L, Tang X, Wan YY, Li Q-J et al.
(
2019
)
.
Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation
.
Nature Communications
vol.
10
,
(
1
)
Zhao L, He R, Long H, Guo B, Jia Q, Qin D, Liu S-Q, Wang Z et al.
(
2018
)
.
Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells
.
Nature Medicine
vol.
24
,
(
10
)
1536
-
1544
.
Omodho B, Miao T, Symonds ALJ, Singh R, Li S, Wang P
(
2018
)
.
Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells
.
Immunity Inflammation and Disease
vol.
6
,
(
2
)
221
-
233
.
Singh R, Miao T, Symonds ALJ, Omodho B, Li S, Wang P
(
2017
)
.
Egr2 and 3 Inhibit T-bet-Mediated IFN-γ Production in T Cells
.
J Immunol
vol.
198
,
(
11
)
4394
-
4402
.
Ogbe A, Miao T, Symonds ALJ, Omodho B, Singh R, Bhullar P, Li S, Wang P
(
2015
)
.
Early Growth Response Genes 2 and 3 Regulate the Expression of Bcl6 and Differentiation of T Follicular Helper Cells*
.
Journal of Biological Chemistry
vol.
290
,
(
33
)
20455
-
20465
.
Li S, Symonds ALJ, Miao T, Sanderson I, Wang P
(
2014
)
.
Modulation of Antigen-Specific T-Cells as Immune Therapy for Chronic Infectious Diseases and Cancer
.
Frontiers in Immunology
vol.
5
,
Miao T, Raymond M, Bhullar P, Ghaffari E, Symonds ALJ, Meier UC, Giovannoni G, Li S et al.
(
2013
)
.
Early growth response gene-2 controls IL-17 expression and Th17 differentiation by negatively regulating Batf
.
J Immunol
vol.
190
,
(
1
)
58
-
65
.
Li S, Miao T, Sebastian M, Bhullar P, Ghaffari E, Liu M, Symonds ALJ, Wang P
(
2012
)
.
The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells
.
Immunity
vol.
37
,
(
4
)
685
-
696
.
Liu M, Miao T, Zhu H, Symonds ALJ, Li L, Schurich A, Maini MK, Zhang J et al.
(
2012
)
.
IL-2-Engineered nano-APC Effectively Activates Viral Antigen-Mediated T Cell Responses from Chronic Hepatitis B Virus-Infected Patients
.
JOURNAL OF IMMUNOLOGY
vol.
188
,
(
3
)
1534
-
1543
.
Li SL, Symonds ALJ, Zhu B, Liu MY, Raymond MV, Miao TZ, Wang P
(
2011
)
.
Early Growth Response Gene-2 (Egr-2) Regulates the Development of B and T Cells
.
PLOS ONE
vol.
6
,
(
4
)
Article
e18498
,
Zhu B, Symonds ALJ, Martin JE, Kioussis D, Wraith DC, Li SL, Wang P
(
2008
)
.
Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease
.
J EXP MED
vol.
205
,
(
10
)
2295
-
2307
.
WANG P, odriguez-Cabezas ME, Li S, Sundstedt A, Nicolson K, Khalid S, Symonds A, Minaee S et al.
(
2006
)
.
Persistent antigenic stimulation alters the transcription program in T cells, resulting in antigen-specific tolerance
.
Eur J Immunol.
vol.
36
,
1374
-
1385
.