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Research

Publications: Dr Alistair Symonds

Wang X, Zha H, Wu W, Yuan T, Xie S, Jin Z, Long H, Yang F et al. ( 2023 ) . CD200+ cytotoxic T lymphocytes in the tumor microenvironment are crucial for efficacious anti–PD-1/PD-L1 therapy . Science Translational Medicine vol. 15 , ( 679 )
Symonds ALJ, Miao T, Busharat Z, Li S, Wang P ( 2022 ) . Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells . Cancer Immunology, Immunotherapy vol. 72 , ( 5 ) 1139 - 1151 .
Symonds AL, Zheng W, Miao T, Wang H, Wang T, Kiome R, Hou X, Li S et al. ( 2020 ) . Egr2 and 3 control inflammation, but maintain homeostasis, of PD-1high memory phenotype CD4 T cells . Life Science Alliance vol. 3 , ( 9 )
Zhou J, Huang S, Wang Z, Huang J, Xu L, Tang X, Wan YY, Li Q-J et al. ( 2019 ) . Targeting EZH2 histone methyltransferase activity alleviates experimental intestinal inflammation . Nature Communications vol. 10 , ( 1 )
Zhao L, He R, Long H, Guo B, Jia Q, Qin D, Liu S-Q, Wang Z et al. ( 2018 ) . Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells . Nature Medicine vol. 24 , ( 10 ) 1536 - 1544 .
Omodho B, Miao T, Symonds ALJ, Singh R, Li S, Wang P ( 2018 ) . Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells . Immunity Inflammation and Disease vol. 6 , ( 2 ) 221 - 233 .
Singh R, Miao T, Symonds ALJ, Omodho B, Li S, Wang P ( 2017 ) . Egr2 and 3 Inhibit T-bet-Mediated IFN-γ Production in T Cells . J Immunol vol. 198 , ( 11 ) 4394 - 4402 .