Publications: Prof Seif Shaheen
Janson C, Shaheen SO
(
2025
)
.
Chapter 5 Infection
.
Small Lungs and Obstructed Airways
,
Elsevier
Shaheen SO
(
2025
)
.
Chapter 8 Early life origins of impaired adult lung function∗
.
Small Lungs and Obstructed Airways
,
Elsevier
Talaei M, Waters S, Portas L, Jacobs BM, Dodd JW, Marshall CR, Minelli C, Shaheen SO
(
2024
)
.
Lung development genes, adult lung function and cognitive traits
.
Brain Communications
vol.
6
,
(
6
)
Callanan S, Talaei M, Delahunt A, Shaheen SO, McAuliffe FM
(
2024
)
.
Low glycaemic index diet in pregnancy and child asthma: follow-up of the ROLO trial
.
British Journal Of Nutrition1
-
11
.
Callanan S, Talaei M, Delahunt A, Shaheen SO, McAuliffe FM
(
2024
)
.
Low glycaemic index diet in pregnancy and child asthma and eczema: follow-up of the ROLO trial
.
Proceedings of The Nutrition Society
.
vol.
83
,
Rogers NT, Cummins S, Jones CP, Mytton OT, Roberts CH, Shaheen SO, Shah SA, Sheikh A et al.
(
2024
)
.
The UK Soft Drinks Industry Levy and childhood hospital admissions for asthma in England
.
Nature Communications
vol.
15
,
(
1
)
Shaheen SO
(
2024
)
.
Toxic metals and lung health: silent poisons?
.
Thorax
vol.
79
,
(
7
)
601
-
602
.
Melén E, Faner R, Allinson JP, Bui D, Bush A, Custovic A, Garcia-Aymerich J, Guerra S et al.
(
2024
)
.
Lung-function trajectories: relevance and implementation in clinical practice
.
The Lancet
vol.
403
,
(
10435
)
1494
-
1503
.
van der Plaat DA, Lenoir A, Dharmage S, Potts J, Real FG, Shaheen SO, Jarvis D, Minelli C et al.
(
2024
)
.
Effects of testosterone and sex hormone binding globulin on lung function in males and females: a multivariable Mendelian Randomisation study
.
Thorax
vol.
79
,
(
6
)
564
-
572
.
Hajmohammadi H, Talaei M, Fecht D, Wang W, Vivaldi G, Faustini SE, Richter AG, Shaheen SO et al.
(
2024
)
.
Long-term air pollution exposure and risk of SARS-CoV-2 infection: A UK-wide cohort study
.
Respiratory Medicine
vol.
224
,
Lessof C, Cooper R, Wong A, Bendayan R, Caleyachetty R, Cheshire H, Cosco T, Elhakeem A et al.
(
2023
)
.
Comparison of devices used to measure blood pressure, grip strength and lung function: A randomised cross-over study
.
PLOS ONE
vol.
18
,
(
12
)
Shaheen S
(
2023
)
.
Lower respiratory tract infections in early childhood
.
The Lancet
vol.
402
,
(
10418
)
Hajmohammadi H, Talaei M, Fecht D, Wang W, Vivaldi G, Faustini S, Richter A, Shaheen S et al.
(
2023
)
.
Long-term air pollution exposure and risk of SARS-CoV-2 infection: A UK-wide cohort study
.
Conference:
Epidemiology
Vivaldi G, Pfeffer P, Talaei M, Basera TJ, Shaheen S, Martineau A
(
2023
)
.
Long-term symptom profiles after COVID-19 versus other acute respiratory infections: an analysis of data from the COVIDENCE UK study
.
EClinicalMedicine
Shaheen S
(
2023
)
.
Lessons from UK historical cohort studies of lower respiratory tract infections
.
The Lancet Child & Adolescent Health
vol.
7
,
(
7
)
Talaei M, Emmett PM, Granell R, Tabatabaeian H, Northstone K, Bergström A, Shaheen SO
(
2023
)
.
Dietary patterns, lung function and asthma in childhood: a longitudinal study
.
Respiratory Research
vol.
24
,
(
1
)
Holt H, Jolliffe DA, Talaei M, Faustini S, Vivaldi G, Greenig M, Richter AG, Lyons RA et al.
(
2023
)
.
Incidence determinants and serological correlates of reactive symptoms following SARS-CoV-2 vaccination
.
npj Vaccines
vol.
8
,
(
1
)
Vivaldi G, Jolliffe DA, Faustini S, Holt H, Talaei M, Tydeman F, Richter AG, Shaheen SO et al.
(
2022
)
.
Correlation between post-vaccination titres of anti-Spike antibodies and protection against breakthrough SARS-CoV-2 infection in 7530 UK adults
.
Conference:
06.01 - Epidemiology
Jolliffe DA, Faustini SE, Holt H, Talaei M, Vivaldi G, Richter AG, Shaheen SO, Martineau AR
(
2022
)
.
Determinants of antibody responses to primary courses and booster doses of SARS-CoV-2 vaccines in 9,101 UK adults
.
Conference:
10.01 - Respiratory infections and bronchiectasis
Talaei Pashiri M, Faustini S, Holt H, Jolliffe DA, Vivaldi G, G Richter A, Shaheen SO, Martineau AR
(
2022
)
.
Determinants of pre-vaccination SARS-CoV-2 seropositivity: a population-based longitudinal study (COVIDENCE UK)
.
Conference:
06.01 - Epidemiology
Vivaldi G, Jolliffe DA, Holt H, Talaei M, Tydeman F, Shaheen SO, Martineau AR
(
2022
)
.
Risk factors for breakthrough COVID-19 in 15,804 UK adults after primary and booster doses of SARS-CoV-2 vaccines
.
Conference:
06.01 - Epidemiology
Jolliffe DA, Holt H, Talaei M, Sheikh A, Griffiths CJ, Shaheen SO, Relton C, Martineau AR
(
2022
)
.
Vitamin D to prevent COVID-19 or other acute respiratory infections: phase 3 randomised controlled trial (CORONAVIT)
.
Conference:
10.01 - Respiratory infections and bronchiectasis
Tydeman F, Pfeffer PE, Vivaldi G, Holt H, Talaei M, Jolliffe D, Davies G, Lyons RA et al.
(
2022
)
.
Rebound in asthma exacerbations following relaxation of COVID-19 restrictions: a longitudinal population-based study (COVIDENCE UK)
.
Thorax
vol.
78
,
(
8
)
752
-
759
.
Vivaldi G, Jolliffe D, Holt H, Talaei M, Tydeman F, Shaheen S, Martineau A
(
2022
)
.
S37 Risk factors for breakthrough COVID-19 in 14,713 UK adults after primary and booster doses of SARS-CoV-2 vaccines
.
Conference:
‘Outbreak!’ – COVID-19 epidemiologya25.2
-
a2a26
.
Jolliffe D, Holt H, Talaei M, Sheikh A, Griffiths C, Shaheen S, Relton C, Martineau A
(
2022
)
.
S42 Vitamin D to prevent COVID-19 or other acute respiratory infections: phase 3 randomised controlled trial (CORONAVIT)
.
Conference:
‘The fast and the furious’ – Clinical studies in COVID-19a29.1
-
a2a29
.
Tarazona-Meza C, De Castro Mendes F, Charles D, Curi-Hallal AL, Ducharme-Smith K, Da Silva FM, Mora-Garcia G, Ruiz-Diaz MS et al.
(
2022
)
.
Urinary excretion of phytoestrogens and lung function in US adults
.
Annals of Epidemiology
vol.
75
,
Holt H, Relton C, Talaei M, Symons J, Davies MR, Jolliffe DA, Vivaldi G, Tydeman F et al.
(
2022
)
.
Cohort Profile: Longitudinal population-based study of COVID-19 in UK adults (COVIDENCE UK)
.
International Journal of Epidemiology
vol.
52
,
(
1
)
e46
-
e56
.
Jolliffe DA, Faustini SE, Holt H, Perdek N, Maltby S, Talaei M, Greenig M, Vivaldi G et al.
(
2022
)
.
Determinants of Antibody Responses to SARS-CoV-2 Vaccines: Population-Based Longitudinal Study (COVIDENCE UK)
.
Vaccines
vol.
10
,
(
10
)
1601
-
1601
.
Vivaldi G, Jolliffe D, Tydeman F, Talaei M, Davies GA, Lyons RA, GRIFFITHS CJ, Kee F et al.
(
2022
)
.
Risk factors for SARS-CoV-2 infection after primary vaccination with ChAdOx1 nCoV-19 or BNT1262b2 and after booster vaccination with BNT1262b2 or mRNA-1273: a population-based cohort study (COVIDENCE UK)
.
The Lancet Regional Health Europe
Jolliffe DA, Holt H, Greenig M, Talaei M, Perdek N, Pfeffer P, Vivaldi G, Maltby S et al.
(
2022
)
.
Effect of a test-and-treat approach to vitamin D supplementation on risk of all cause acute respiratory tract infection and covid-19: Phase 3 randomised controlled trial (CORONAVIT)
.
The BMJ
Vivaldi G, Jolliffe DA, Faustini S, Shields AM, Holt H, Perdek N, Talaei M, Tydeman F et al.
(
2022
)
.
Correlation Between Postvaccination Anti-Spike Antibody Titers and Protection Against Breakthrough Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A Population-Based Longitudinal Study
.
The Journal of Infectious Diseases
vol.
226
,
(
11
)
1903
-
1908
.
Talaei M, Faustini S, Holt H, Jolliffe DA, Vivaldi G, Greenig M, Perdek N, Maltby S et al.
(
2022
)
.
Determinants of pre-vaccination antibody responses to SARS-CoV-2: a population-based longitudinal study (COVIDENCE UK)
.
BMC Medicine
vol.
20
,
(
1
)
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al.
(
2021
)
.
Risk Factors for Developing COVID-19: A Population-Based Longitudinal Study (COVIDENCE UK)
.
Thorax
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young KS, Davies MR et al.
(
2021
)
.
Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
.
Thorax
vol.
77
,
(
9
)
900
-
912
.
Pashiri MT, Emmett PM, Northstone K, Shaheen SO
(
2021
)
.
Dietary patterns and lung function in childhood: A longitudinal study
.
Conference:
Paediatric respiratory epidemiology
Talaei M, Hughes DA, Mahmoud O, Emmett PM, Granell R, Guerra S, Shaheen SO
(
2021
)
.
Dietary intake of vitamin A, lung function and incident asthma in childhood
.
European Respiratory Journal
vol.
58
,
(
4
)
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al.
(
2021
)
.
Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK)
.
MedRvx
Talaei M, Sdona E, Calder PC, Jones LR, Emmett PM, Granell R, Bergström A, Melén E et al.
(
2021
)
.
Intake of n-3 polyunsaturated fatty acids in childhood, FADS genotype and incident asthma
.
European Respiratory Journal
vol.
58
,
(
3
)
Portas L, Pereira M, Shaheen SO, Wyss AB, London SJ, Burney PGJ, Hind M, Dean CH et al.
(
2020
)
.
Lung Development Genes and Adult Lung Function
.
American Journal of Respiratory and Critical Care Medicine
vol.
202
,
(
6
)
853
-
865
.
Shaheen SO, Gissler M, Devereux G, Erkkola M, Kinnunen TI, Mcardle H, Sheikh A, Hemminki E et al.
(
2020
)
.
Maternal iron supplementation in pregnancy and asthma in the offspring: follow-up of a randomised trial in Finland
.
European Respiratory Journal
vol.
55
,
(
6
)
Bédard A, Northstone K, Henderson AJ, Shaheen SO
(
2019
)
.
Mediterranean diet during pregnancy and childhood respiratory and atopic outcomes: birth cohort study
.
European Respiratory Journal
vol.
55
,
(
3
)
Talaei M, Calder P, Shaheen S
(
2019
)
.
S131 Dietary intake of long-chain n-3 polyunsaturated fatty acids and risk of childhood asthma
.
Thorax
.
Conference:
Advances in asthma science and treatment
vol.
74
,
Shaheen S
(
2019
)
.
Elucidating the causes of asthma: how can we do better?
.
The Lancet Respiratory Medicine
vol.
7
,
(
8
)
SHAHEEN SO, Lundholm C, Brew B, Almqvist C
(
2019
)
.
Prescribed analgesics in pregnancy and risk of childhood asthma
.
European Respiratory Journal
Bédard A, Northstone K, Holloway JW, Henderson AJ, Shaheen SO
(
2018
)
.
Maternal dietary antioxidant intake in pregnancy and childhood respiratory and atopic outcomes: birth cohort study
.
European Respiratory Journal
vol.
52
,
(
2
)
Bédard A, Lewis SJ, Burgess S, Henderson AJ, Shaheen SO
(
2018
)
.
Maternal iron status during pregnancy and respiratory and atopic outcomes in the offspring: a Mendelian randomisation study
.
BMJ Open Respir Res
vol.
5
,
(
1
)
e000275
-
e000275
.
Shaheen SO
(
2018
)
.
Uric acid, lung function and COPD: a causal link is unlikely
.
Thorax
vol.
73
,
(
8
)
Shaheen SO, Macdonald-Wallis C, Lawlor DA, Henderson AJ
(
2017
)
.
Haemoglobin concentrations in pregnancy and respiratory and allergic outcomes in childhood: Birth cohort study
.
Clinical & Experimental Allergy
Brugha R, Lowe R, Henderson AJ, Holloway JW, Rakyan V, Wozniak E, Mahmud N, Seymour K et al.
(
2017
)
.
DNA methylation profiles between airway epithelium and proxy tissues in children
.
Acta Paediatrica
Okely JA, Shaheen SO, Weiss A, Gale CR
(
2017
)
.
Wellbeing and chronic lung disease incidence: The Survey of Health, Ageing and Retirement in Europe
.
PLoS One
vol.
12
,
(
7
)
Article
0181320
,
e0181320
-
e0181320
.
SHAHEEN SO, Bedard A
(
2017
)
.
Maternal intake of sugar during pregnancy and childhood respiratory and atopic outcomes
.
European Respiratory Journal
Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA
(
2017
)
.
Combined Impact of Smoking and Early Life Exposures on Adult Lung Function Trajectories
.
Am J Respir Crit Care Med
Varraso R, Shaheen SO
(
2017
)
.
Could a healthy diet attenuate COPD risk in smokers?
.
Thorax
vol.
72
,
(
6
)
Polanska K, Krol A, Kaluzny P, Ligocka D, Mikolajewska K, Shaheen S, Walton R, Hanke W
(
2016
)
.
Estimation of Saliva Cotinine Cut-Off Points for Active and Passive Smoking during Pregnancy-Polish Mother and Child Cohort (REPRO_PL)
.
Int J Environ Res Public Health
vol.
13
,
(
12
)
Gallo V, Dijk FN, Holloway JW, RIng SM, Koppelman GH, Postma DS, Strachan DP, Granell R et al.
(
2016
)
.
TRPA1 gene polymorphisms and childhood asthma
.
Pediatric Allergy and Immunology
Allinson JP, Hardy R, Donaldson GC, Shaheen SO, Kuh D, Wedzicha JA
(
2016
)
.
The Presence of Chronic Mucus Hypersecretion across Adult Life in Relation to Chronic Obstructive Pulmonary Disease Development
.
American Journal of Respiratory and Critical Care Medicine
vol.
193
,
(
6
)
662
-
672
.
Griffiths M, Goldring S, Griffiths C, Shaheen SO, Martineau A, Cross L, Robinson S, Warner JO et al.
(
2015
)
.
Effects of Pre-Natal Vitamin D Supplementation with Partial Correction of Vitamin D Deficiency on Early Life Healthcare Utilisation: A Randomised Controlled Trial
.
PLOS ONE
vol.
10
,
(
12
)
Shaheen SO, Macdonald-Wallis C, Lawlor DA, Henderson AJ
(
2015
)
.
Hypertensive disorders of pregnancy, respiratory outcomes and atopy in childhood
.
European Respiratory Journal
vol.
47
,
(
1
)
156
-
165
.
Cai Y, Shaheen SO, Hardy R, Kuh D, Hansell AL
(
2015
)
.
Birth weight, early childhood growth and lung function in middle to early old age: 1946 British birth cohort
.
Thorax
vol.
71
,
(
10
)
916
-
922
.
Lee DCP, Walker SA, Byrne AJ, Gregory LG, Buckley J, Bush A, Shaheen SO, Saglani S et al.
(
2015
)
.
Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life
.
Thorax
vol.
70
,
(
6
)
Shaheen SO, Rutterford CM, Lewis SJ, Ring SM, Holloway JW, Golding J, Henderson AJ
(
2015
)
.
Maternal selenium status in pregnancy, offspring glutathione peroxidase 4 genotype, and childhood asthma: To the editor
.
Journal of Allergy and Clinical Immunology
vol.
135
,
Article
4
,
1083
-
1085.e3
.
Shaheen SO
(
2014
)
.
Acetaminophen and childhood asthma: Pill-popping at our peril?
.
Journal of Allergy and Clinical Immunology
vol.
135
,
(
2
)
449
-
450
.
Shaheen SO
(
2014
)
.
Antioxidants and respiratory disease: the uric acid paradox
.
Thorax
vol.
69
,
(
11
)
Janha RE, Worwui A, Linton KJ, Shaheen SO, Sisay-Joof F, Walton RT
(
2014
)
.
Inactive alleles of cytochrome P450 2C19 may be positively selected in human evolution
.
BMC Evol Biol
vol.
14
,
Okubo H, Shaheen SO, Ntani G, Jameson KA, Syddall HE, Sayer AA, Dennison EM, Cooper C et al.
(
2014
)
.
Processed meat consumption and lung function: Modification by antioxidants and smoking
.
European Respiratory Journal
vol.
43
,
(
4
)
972
-
982
.
Vawda S, Mansour R, Takeda A, Funnell P, Kerry S, Mudway I, Jamaludin J, Shaheen S et al.
(
2013
)
.
Associations Between Inflammatory and Immune Response Genes and Adverse Respiratory Outcomes Following Exposure to Outdoor Air Pollution: A HuGE Systematic Review
.
American Journal of Epidemiology
vol.
179
,
(
4
)
432
-
442
.
Wills AK, Shaheen SO, Granell R, Henderson AJ, Fraser WD, Lawlor DA
(
2013
)
.
Maternal 25-hydroxyvitamin D and its association with childhood atopic outcomes and lung function
.
Clinical and Experimental Allergy
vol.
43
,
(
10
)
1180
-
1188
.
Shaheen SO, Rutterford C, Zuccolo L, Ring SM, Smith GD, Holloway JW, Henderson AJ
(
2013
)
.
Prenatal alcohol exposure and childhood atopic disease: A Mendelian randomization approach
.
Journal of Allergy and Clinical Immunology
vol.
133
,
(
1
)
225
-
232.e5
.
Dennison EM, Dhanwal DK, Shaheen SO, Azagra R, Reading I, Jameson KA, Sayer AA, Cooper C
(
2013
)
.
Is lung function associated with bone mineral density? Results from the Hertfordshire Cohort Study
.
Archives of Osteoporosis
vol.
8
,
(
1-2
)
Goldring ST, Griffiths CJ, Martineau AR, Robinson S, Yu C, Poulton S, Kirkby JC, Stocks J et al.
(
2013
)
.
Prenatal vitamin d supplementation and child respiratory health: a randomised controlled trial
.
PLoS One
vol.
8
,
(
6
)
Henderson AJ, Shaheen SO
(
2012
)
.
Acetaminophen and asthma
.
Paediatric Respiratory Reviews
vol.
14
,
(
1
)
9
-
16
.
Relton CL, Groom A, St. Pourcain B, Sayers AE, Swan DC, Embleton ND, Pearce MS, Ring SM et al.
(
2012
)
.
DNA methylation patterns in cord blood DNA and body size in childhood
.
PLoS ONE
vol.
7
,
(
3
)
Shaheen SO, Martineau AR
(
2012
)
.
Vitamin D and Chronic Obstructive Pulmonary Disease: Justified Optimism or False Hope?
.
American Journal of Respiratory and Critical Care Medicine
vol.
185
,
(
3
)
239
-
241
.
Goldring S, O. Warner J, O. Shaheen S, J. Boyle R
(
2011
)
.
Early Life Vitamin D Status and Lung Development
.
Current Respiratory Medicine Reviews
vol.
7
,
(
6
)
396
-
403
.
Soler Artigas M, Wain LV, Repapi E, Obeidat M, Sayers I, Burton PR, Johnson T, Zhao JH et al.
(
2011
)
.
Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function
.
Am J Respir Crit Care Med
vol.
184
,
(
7
)
786
-
795
.
Shaheen SO, Jameson KA, Robinson SM, Boucher BJ, Syddall HE, Sayer AA, Cooper C, Holloway JW et al.
(
2011
)
.
Relationship of vitamin D status to adult lung function and COPD
.
Thorax
vol.
66
,
(
8
)
692
-
698
.
Shaheen SO
(
2011
)
.
Commentary: Paracetamol and asthma--lessons from the antibiotic hypothesis?
.
Int J Epidemiol
vol.
40
,
(
3
)
667
-
669
.
Minelli C, Wei I, Sagoo G, Jarvis D, Shaheen S, Burney P
(
2011
)
.
Interactive Effects of Antioxidant Genes and Air Pollution on Respiratory Function and Airway Disease: A HuGE Review
.
American Journal of Epidemiology
vol.
173
,
(
6
)
603
-
620
.
Shaheen SO, Newson RB, Ring SM, Rose-Zerilli MJ, Holloway JW, Henderson AJ
(
2010
)
.
Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma
.
J Allergy Clin Immunol
vol.
126
,
(
6
)
1141
-
8.e7
.
Greenough A, Shaheen SO, Shennan A, Seed PT, Poston L
(
2010
)
.
Respiratory outcomes in early childhood following antenatal vitamin C and E supplementation
.
Thorax
vol.
65
,
(
11
)
998
-
1003
.
Henderson AJ, Newson RB, Rose-Zerilli M, Ring SM, Holloway JW, Shaheen SO
(
2010
)
.
Maternal Nrf2 and gluthathione-S-transferase polymorphisms do not modify associations of prenatal tobacco smoke exposure with asthma and lung function in school-aged children
.
Thorax
vol.
65
,
(
10
)
897
-
902
.
Shaheen SO, Jameson KA, Syddall HE, Aihie Sayer A, Dennison EM, Cooper C, Robinson SM, Hertfordshire Cohort Study Group
(
2010
)
.
The relationship of dietary patterns with adult lung function and COPD
.
Eur Respir J
vol.
36
,
(
2
)
277
-
284
.
Shaheen SO, Newson RB, Smith GD, Henderson AJ
(
2010
)
.
Prenatal paracetamol exposure and asthma: further evidence against confounding
.
Int J Epidemiol
vol.
39
,
(
3
)
790
-
794
.
Bakolis I, Hooper R, Thompson RL, Shaheen SO
(
2010
)
.
Dietary patterns and adult asthma: population-based case-control study
.
Allergy
vol.
65
,
(
5
)
606
-
615
.
Minelli C, Granell R, Newson R, Rose-Zerilli MJ, Torrent M, Ring SM, Holloway JW, Shaheen SO et al.
(
2010
)
.
Glutathione-S-transferase genes and asthma phenotypes: a Human Genome Epidemiology (HuGE) systematic review and meta-analysis including unpublished data
.
Int J Epidemiol
vol.
39
,
(
2
)
539
-
562
.
Repapi E, Sayers I, Wain LV, Burton PR, Johnson T, Obeidat M, Zhao JH, Ramasamy A et al.
(
2009
)
.
Genome-wide association study identifies five loci associated with lung function
.
Nature Genetics
vol.
42
,
(
1
)
36
-
44
.
Shaheen SO, Adcock IM
(
2009
)
.
The developmental origins of asthma: does epigenetics hold the key?
.
Am J Respir Crit Care Med
vol.
180
,
(
8
)
690
-
691
.
Rose-Zerilli MJ, Barton SJ, Henderson AJ, Shaheen SO, Holloway JW
(
2009
)
.
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