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Research

Publications: Dr Divyen Shah

Gala AAD, Kumar H, Sedani S, Openshaw-Lawrence N, Verkuijl JM, Glogowski N, Steingold A, Ponnusamy V et al. ( 2022 ) . Alterations in the Stool Microbiome in Newborns Undergoing Mild Therapeutic Hypothermia after Hypoxic-Ischemic Encephalopathy . Developmental Neuroscience vol. 44 , ( 4-5 ) 373 - 383 .
Pavel AM, Rennie JM, de Vries LS, Blennow M, Foran A, Shah DK, Pressler RM, Kapellou O et al. ( 2022 ) . Neonatal Seizure Management: Is the Timing of Treatment Critical? . J Pediatr vol. 243 , 61 - 68.e2 .
Padhiar V, Rosser G, Openshaw-Lawrence N, Kappelou O, Evanson J, Kaya B, Shah DK ( 2022 ) . Association between Multi-Organ Involvement and Brain Injury in Cooled Newborns: A Statistical Approach . Dev Neurosci vol. 44 , ( 4-5 ) 384 - 393 .
Pereira S, Patel R, Zaima A, Tvarozkova K, Chisholm P, Kappelou O, Evanson J, Chandraharan E et al. ( 2022 ) . Physiological CTG categorization in types of hypoxia compared with MRI and neurodevelopmental outcome in infants with HIE . Journal of Maternal-Fetal and Neonatal Medicine vol. 35 , ( 25 ) 9675 - 9683 .
Nixon R, Ip THR, Jenkins B, Yip PK, Clarke P, Ponnusamy V, Michael-Titus AT, Koulman A et al. ( 2021 ) . Lipid profiles from dried blood spots reveal lipidomic signatures of newborns undergoing mild therapeutic hypothermia after hypoxic-ischemic encephalopathy . Nutrients vol. 13 , ( 12 )
Ponnusamy V, Ip RTH, Mohamed MAEK, Clarke P, Wozniak E, Mein C, Schwendimann L, Barlas A et al. ( 2021 ) . Neuronal let-7b-5p acts through the Hippo-YAP pathway in neonatal encephalopathy . Communications Biology vol. 4 , ( 1 )
Pereira SS, Sinha AK, Shah DK, Kempley ST ( 2021 ) . Common carotid artery blood flow volume in extremely preterm infants . Acta Paediatrica, International Journal of Paediatrics vol. 110 , ( 4 ) 1157 - 1165 .
Shah DK, Yip PK, Barlas A, Tharmapoopathy P, Ponnusamy V, Michael-Titus AT, Chisholm P ( 2020 ) . Raised Plasma Neurofilament Light Protein Levels After Rewarming Are Associated With Adverse Neurodevelopmental Outcomes in Newborns After Therapeutic Hypothermia . Frontiers in Neurology vol. 11 ,
Tharmapoopathy P, Chisholm P, Barlas A, Varsami M, Gupta N, Ekitzidou G, Ponnusamy V, Kappelou O et al. ( 2020 ) . In clinical practice, cerebral MRI in newborns is highly predictive of neurodevelopmental outcome after therapeutic hypothermia . European Journal of Paediatric Neurology vol. 25 , 127 - 133 .
Pereira SS, Sinha AK, Morris JK, Wertheim DF, Shah DK, Kempley ST ( 2019 ) . Blood pressure intervention levels in preterm infants: pilot randomised trial . Arch Dis Child Fetal Neonatal Ed vol. 104 , ( 3 ) F298 - F305 .
Tharmapoopathy P, Chisholm P, Barlas A, Varsami M, Gupta N, Ekitzidou G, Ponnusamy V, Kappelou O et al. ( 2019 ) . In clinical practice, cerebral MRI in newborns is highly predictive of neurodevelopmental outcome after therapeutic hypothermia . European Journal of Paediatric Neurology
Rennie JM, de Vries LS, Blennow M, Foran A, Shah DK, Livingstone V, van Huffelen AC, Mathieson SR et al. ( 2018 ) . Characterisation of neonatal seizures and their treatment using continuous EEG monitoring: a multicentre experience . Archives of Disease in Childhood: Fetal and Neonatal Edition vol. 104 , ( 5 ) F493 - F501 .
Shah DK, Ponnusamy V, Evanson J, Kapellou O, Ekitzidou G, Gupta N, Clarke P, Michael-Titus AT et al. ( 2018 ) . Raised plasma neurofilament light protein levels are associated with abnormal MRI outcomes in newborns undergoing therapeutic hypothermia . Frontiers in Neurology vol. 9 , ( MAR )
Pereira SS, Kempley ST, Shah DK, Morris JK, Sinha AK ( 2018 ) . Early echocardiography does not predict subsequent treatment of symptomatic patent ductus arteriosus in extremely preterm infants . Acta Paediatr vol. 107 , ( 11 ) 1909 - 1916 .
Pereira SS, Kempley ST, Wertheim DF, Sinha AK, Morris JK, Shah DK ( 2018 ) . Investigation of EEG Activity Compared with Mean Arterial Blood Pressure in Extremely Preterm Infants . Front Neurol vol. 9 ,
Lee WLA, Michael-Titus AT, Shah DK ( 2017 ) . Hypoxic-Ischaemic Encephalopathy and the Blood-Brain Barrier in Neonates . Developmental Neuroscience vol. 39 , ( 1-4 ) 49 - 58 .
Dunne JM, Wertheim D, Clarke P, Kapellou O, Chisholm P, Boardman JP, Shah DK ( 2017 ) . Automated electroencephalographic discontinuity in cooled newborns predicts cerebral MRI and neurodevelopmental outcome . Archives of Disease in Childhood: Fetal and Neonatal Edition vol. 102 , ( 1 ) F58 - F64 .
Parker E, Shah D, Clarke P ( 2016 ) . EVOLUTION OF AMPLITUDE - INTEGRATED ELECTROENCEPHALOGRAPHY DURING THE EARLY NEONATAL PERIOD IN INFANTS WITH FATAL HYPOXIC-ISCHAEMIC ENCEPHALOPATHY . EUROPEAN JOURNAL OF PEDIATRICS . vol. 175 , 1684 - 1684 .
Kage A, Cowan F, Kempley S, Finer S, Hogg M, Hitman G, Shah D ( 2016 ) . HEAD CIRCUMFERENCE IS DIRECTLY RELATED TO SPECIFIC LINEAR MEASUREMENTS OF CEREBRAL STRUCTURES IN A LOCAL EAST LONDON POPULATION OF WELL NEWBORNS OF SOUTH ASIAN DIASPORA . EUROPEAN JOURNAL OF PEDIATRICS . vol. 175 , 1676 - 1676 .
Kempley S, Pereira S, Sinha A, Shah D ( 2016 ) . Randomised trial of different blood pressure intervention levels to trigger circulatory support in extremely preterm infants: a pilot trial reporting clinical and haemodynamic outcomes . EUROPEAN JOURNAL OF PEDIATRICS . vol. 175 , 1583 - 1583 .
Kalra V, Shaw SS, Dixon S, Shah DK, Clarke P ( 2016 ) . Cerebral function monitoring on a general paediatric ward: feasibility and potential . European Journal of Pediatrics vol. 175 , ( 8 ) 1059 - 1064 .
Ponnusamy V, Kapellou O, Yip E, Evanson J, Wong LF, Michael-Titus A, Yip PK, Shah DK ( 2016 ) . A study of microRNAs from dried blood spots in newborns after perinatal asphyxia: A simple and feasible biosampling method . Pediatric Research vol. 79 , ( 5 ) 799 - 805 .
Pereira S, Jones C, Shah D, Wertheim D, Kempley S ( 2014 ) . PC.120 Relationship between EEG and continuously measured invasive blood pressure in extremely preterm infants in the first three days of life . Arch Dis Child Fetal Neonatal Ed . vol. 99 Suppl 1 , A77 - A79 .
Jones C, Pereira S, Wertheim D, Shah D, Kempley S ( 2014 ) . PC.51 Variability of Blood Pressure in Extremely Preterm Infants in the First 72 hrs of Postnatal Adaptation . Arch Dis Child Fetal Neonatal Ed . vol. 99 Suppl 1 , A53 - A54 .
Fong F, Rogozinska E, Allotey J, Kempley S, Shah DK, Thangaratinam S ( 2014 ) . Development of maternal and neonatal composite outcomes for trials evaluating management of late-onset pre-eclampsia . Hypertens Pregnancy vol. 33 , ( 2 ) 115 - 131 .
Reynolds LC, Pineda RG, Mathur A, Vavasseur C, Shah DK, Liao S, Inder T ( 2014 ) . Cerebral maturation on amplitude-integrated electroencephalography and perinatal exposures in preterm infants . Acta Paediatrica, International Journal of Paediatrics vol. 103 , ( 3 )
Shah DK, Mathur A ( 2014 ) . Amplitude-integrated EEG and the newborn infant . Current Pediatric Reviews vol. 10 , ( 1 ) 10 - 15 .
Shah DK, Mathur A ( 2014 ) . Amplitude-integrated EEG and the newborn infant . Curr Pediatr Rev vol. 10 , ( 1 ) 11 - 15 .
Shah DK, Wusthoff CJ, Clarke P, Wyatt JS, Ramaiah SM, Dias RJ, Becher JC, Kapellou O et al. ( 2014 ) . Electrographic seizures are associated with brain injury in newborns undergoing therapeutic hypothermia . Archives of Disease in Childhood: Fetal and Neonatal Edition vol. 99 , ( 3 )
Fong F, Rogozinska E, Allotey J, Kempley S, Shah D, Thangaratinam S ( 2013 ) . Development of maternal and neonatal composite outcomes for trials evaluating timing of delivery in women with pre-eclampsia . Trials vol. 14 , ( Suppl 1 )
Fong F, Rogozinska E, Allotey J, Kempley S, Shah D, Thangaratinam S ( 2013 ) . PP.88 Identification of Clinically Important Components of Maternal and Neonatal Composite Outcomes to Assess the Effect of Timing of Delivery in Women with Mild to Moderate Pre-Eclampsia at 34 to 37 Weeks . Archives of Disease in Childhood - Fetal and Neonatal Edition vol. 98 , ( Suppl 1 )
Reynolds LC, Pineda RG, Mathur A, Vavasseur C, Shah DK, Liao S, Inder T ( 2013 ) . Cerebral maturation on amplitude-integrated electroencephalography and perinatal exposures in preterm infants . Acta Paediatrica, International Journal of Paediatrics
Shah DK, Boylan GB, Rennie JM ( 2012 ) . Monitoring of seizures in the newborn . Archives of Disease in Childhood: Fetal and Neonatal Edition vol. 97 , ( 1 )
Mohinuddin S, Mohidin R, Ratnavel N, Sinha A, Shah D ( 2011 ) . INFANTS WITH NEONATAL ENCEPHALOPATHY TRANSPORTED FOR THERAPEUTIC HYPOTHERMIA - ADHERENCE TO STANDARD COOLING CRITERIA . PEDIATRIC RESEARCH vol. 70 , 683 - 683 .
Shah DK, Zempel J, Barton T, Lukas K, Inder TE ( 2010 ) . Electrographic seizures in preterm infants during the first week of life are associated with cerebral injury . Pediatr Res vol. 67 , ( 1 ) 102 - 106 .
Shah DK, de Vries LS, Hellström-Westas L, Toet MC, Inder TE ( 2008 ) . Amplitude-integrated electroencephalography in the newborn: a valuable tool . Pediatrics vol. 122 , ( 4 ) 863 - 865 .
Shah DK, Doyle LW, Anderson PJ, Bear M, Daley AJ, Hunt RW, Inder TE ( 2008 ) . Adverse neurodevelopment in preterm infants with postnatal sepsis or necrotizing enterocolitis is mediated by white matter abnormalities on magnetic resonance imaging at term . J Pediatr vol. 153 , ( 2 ) 170 - 175.e1 .
Shah DK, Mackay MT, Lavery S, Watson S, Harvey AS, Zempel J, Mathur A, Inder TE ( 2008 ) . Accuracy of bedside electroencephalographic monitoring in comparison with simultaneous continuous conventional electroencephalography for seizure detection in term infants . Pediatrics vol. 121 , ( 6 ) 1146 - 1154 .
Lavery S, Shah DK, Hunt RW, Filan PM, Doyle LW, Inder TE ( 2008 ) . Single versus bihemispheric amplitude-integrated electroencephalography in relation to cerebral injury and outcome in the term encephalopathic infant . J Paediatr Child Health vol. 44 , ( 5 ) 285 - 290 .
Shah DK, Guinane C, August P, Austin NC, Woodward LJ, Thompson DK, Warfield SK, Clemett R et al. ( 2006 ) . Reduced occipital regional volumes at term predict impaired visual function in early childhood in very low birth weight infants . Invest Ophthalmol Vis Sci vol. 47 , ( 8 ) 3366 - 3373 .
Shah DK, Anderson PJ, Carlin JB, Pavlovic M, Howard K, Thompson DK, Warfield SK, Inder TE ( 2006 ) . Reduction in cerebellar volumes in preterm infants: relationship to white matter injury and neurodevelopment at two years of age . Pediatr Res vol. 60 , ( 1 ) 97 - 102 .
Shah DK, Tingay DG, Fink AM, Hunt RW, Dargaville PA ( 2005 ) . Magnetic resonance imaging in neonatal nonketotic hyperglycinemia . Pediatr Neurol vol. 33 , ( 1 ) 50 - 52 .
Shah DK, Daley AJ, Hunt RW, Volpe JJ, Inder TE ( 2005 ) . Cerebral white matter injury in the newborn following Escherichia coli meningitis . Eur J Paediatr Neurol vol. 9 , ( 1 ) 13 - 17 .
shah D, Bond M, Kilby AM, Patterson KG ( 2001 ) . Widespread Bone Disease in Acute Myeloid Leukaemia . Leukemia & Lymphoma vol. 42 , ( 6 ) 1309 - 1314 .