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Research

Publications: Mr Claudio Raimondi

Chikh A, Raimondi C ( 2024 ) . Endothelial Neuropilin-1: a multifaced signal transducer with an emerging role in inflammation and atherosclerosis beyond angiogenesis . Biochemical Society Transactions vol. 52 , ( 1 ) 137 - 150 .
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod K et al. ( 2023 ) . Corrigendum to “Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health?” [Redox Biol. 4 (67) (2023) 102864] . Redox Biology vol. 67 ,
Massimo G, Khambata RS, Chapman T, Birchall K, Raimondi C, Shabbir A, Dyson N, Rathod KS et al. ( 2023 ) . Natural mutations of human XDH promote the nitrite (NO2 −)-reductase capacity of xanthine oxidoreductase: A novel mechanism to promote redox health? . Redox Biology vol. 67 ,
Bosseboeuf E, Chikh A, Chaker AB, Mitchell TP, Vignaraja D, Rajendrakumar R, Khambata RS, Nightingale TD et al. ( 2023 ) . Neuropilin-1 interacts with VE-cadherin and TGFBR2 to stabilize adherens junctions and prevent activation of endothelium under flow . Science Signaling vol. 16 , ( 786 )
Chikh A, Sanzà P, Raimondi C, Akinduro O, Warnes G, Chiorino G, Byrne C, Harwood CA et al. ( 2022 ) . Retraction: iASPP is a novel autophagy inhibitor in keratinocytes . Journal of Cell Science vol. 135 , ( 14 )
Dufton NP, Peghaire CR, Osuna-Almagro L, Raimondi C, Kalna V, Chauhan A, Webb G, Yang Y et al. ( 2020 ) . Author Correction: Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis (Nature Communications, (2017), 8, 1, (895), 10.1038/s41467-017-01169-0) . Nature Communications vol. 11 , ( 1 )
Bosseboeuf E, Raimondi C ( 2020 ) . Signalling, Metabolic Pathways and Iron Homeostasis in Endothelial Cells in Health, Atherosclerosis and Alzheimer’s Disease . Cells vol. 9 , ( 9 )
Peghaire C, Dufton NP, Lang M, Salles-Crawley II, Ahnström J, Kalna V, Raimondi C, Pericleous C et al. ( 2019 ) . The transcription factor ERG regulates a low shear stress-induced anti-thrombotic pathway in the microvasculature . Nature Communications vol. 10 , ( 1 )
Issitt T, Bosseboeuf E, De Winter N, Dufton N, Gestri G, Senatore V, Chikh A, Randi AM et al. ( 2018 ) . Neuropilin-1 Controls Endothelial Homeostasis by Regulating Mitochondrial Function and Iron-Dependent Oxidative Stress . iScience vol. 11 , 205 - 223 .
Dufton NP, Peghaire CR, Osuna-Almagro L, Raimondi C, Kalna V, Chauhan A, Webb G, Yang Y et al. ( 2017 ) . Dynamic regulation of canonical TGFβ signalling by endothelial transcription factor ERG protects from liver fibrogenesis . Nature Communications vol. 8 , ( 1 )
Fantin A, Lampropoulou A, Senatore V, Brash JT, Prahst C, Lange CA, Liyanage SE, Raimondi C et al. ( 2017 ) . VEGF165-induced vascular permeability requires NRP1 for ABL-mediated SRC family kinase activation . Journal of Experimental Medicine vol. 214 , ( 4 ) 1049 - 1064 .
Raimondi C, Chikh A, Wheeler AP, Maffucci T, Falasca M ( 2017 ) . Correction: A novel regulatory mechanism links PLCγ1 to PDK1 . Journal of Cell Science vol. 130 , ( 5 ) 1016 - 1016 .
Raimondi C, Calleja V, Ferro R, Fantin A, Riley AM, Potter BVL, Brennan CH, Maffucci T et al. ( 2016 ) . A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion . Scientific Reports vol. 6 , 26142 - 26142 .
Raimondi C, Fantin A, Lampropoulou A, Denti L, Chikh A, Ruhrberg C ( 2014 ) . Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells . J Exp Med vol. 211 , ( 6 ) 1167 - 1183 .
Chikh A, Sanza P, Raimondi C, Akinduro O, Warnes G, Chiorino G, Byrne C, Harwood CA et al. ( 2014 ) . IASPP is a novel autophagy mudulator in keratinocytes . J Cell Science vol. 127 , ( 14 ) 3079 - 3093 .
Ruban EL, Balogun MA, Martins V, Caley M, Raimondi C, O'toole E, Falasca M ( 2014 ) . Phospholipase C beta4 regulates invasion and proliferation in cutaneous SCC <i>in vivo</i> . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 134 , S22 - S22 .
Ruban EL, Martins VL, Caley M, Raimondi C, Falasca M, O'Toole EA ( 2013 ) . Phospholipase C-beta 4 regulates proliferation and invasion in cutaneous SCC . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S73 - S73 .
Raimondi C, Chikh A, Wheeler AP, Maffucci T, Falasca M ( 2012 ) . A novel regulatory mechanism links PLCγ1 to PDK1 . J Cell Sci vol. 125 , ( Pt 13 ) 3153 - 3163 .
Raimondi C, Falasca M ( 2012 ) . Phosphoinositides signalling in cancer: focus on PI3K and PLC . Adv Biol Regul vol. 52 , ( 1 ) 166 - 182 .
Chikh A, Matin RNH, Senatore V, Hufbauer M, Lavery D, Raimondi C, Ostano P, Mello-Grand M et al. ( 2011 ) . iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia . EMBO J vol. 30 , ( 20 ) 4261 - 4273 .
Dominguez V, Raimondi C, Somanath S, Bugliani M, Loder MK, Edling CE, Divecha N, da Silva-Xavier G et al. ( 2011 ) . Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells . J Biol Chem vol. 286 , ( 6 ) 4216 - 4225 .
Falasca M, Raimondi C, Maffucci T ( 2011 ) . Boyden chamber . Methods Mol Biol vol. 769 , 87 - 95 .
Raimondi C, Falasca M ( 2011 ) . Targeting PDK1 in cancer . Curr Med Chem vol. 18 , ( 18 ) 2763 - 2769 .
Raimondi C, Maffucci T, Potter BVI, Falasca M ( 2010 ) . A novel and selective PDK1 inhibitor reduces breast cancer cell invasion and tumour growth . BREAST CANCER RESEARCH . vol. 12 , S3 - S3 .
Maffucci T, Raimondi C, Abu-Hayyeh S, Dominguez V, Sala G, Zachary I, Falasca M ( 2009 ) . A phosphoinositide 3-kinase/phospholipase Cgamma1 pathway regulates fibroblast growth factor-induced capillary tube formation . PLoS One vol. 4 , ( 12 )
Sala G, Dituri F, Raimondi C, Previdi S, Maffucci T, Mazzoletti M, Rossi C, Iezzi M et al. ( 2008 ) . Phospholipase Cgamma1 is required for metastasis development and progression . Cancer Res vol. 68 , ( 24 ) 10187 - 10196 .
Astorri E, Ferrari O, Lima G, Garini A, Arisi M, Manzetti G, Raimondi C ( 1992 ) . Prognostic significance of thallium-201 scintigraphy in patients with previous myocardial infarct . Minerva Cardioangiologica vol. 40 , ( 1-2 ) 7 - 13 .