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Research

Publications: Dr Louise Reynolds

Newport E, Pedrosa AR, Lees D, Dukinfield M, Carter E, Gomez-Escudero J, Casado P, Rajeeve V et al. ( 2022 ) . Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth . Journal of Pathology vol. 256 , ( 2 ) 235 - 247 .
Lechertier T, Reynolds LE, Kim H, Pedrosa AR, Gómez-Escudero J, Muñoz-Félix JM, Batista S, Dukinfield M et al. ( 2020 ) . Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth . Nature Communications vol. 11 , ( 1 )
Reynolds LE, D'Amico G, Lechertier T, Papachristodoulou A, Muñoz-Félix JM, DeArcangelis A, Baker M, Serrels B et al. ( 2017 ) . Dual role of pericyte α6β1-integrin in tumour blood vessels . Journal of Cell Science vol. 130 , ( 9 ) 1583 - 1595 .
Ross J, Webster R, Lechertier T, Reynolds L, Muntoni F, Beeson D, Hodivala-Dilke K, Conti F ( 2015 ) . G.O.9 Integrins are required for synaptic transmission and development of the neuromuscular junction . Neuromuscular Disorders . vol. 25 ,
Gopinathan G, Milagre C, Pearce OMT, Reynolds L, Hodivala-Dilke K, Leinster A, Zhong H, Hollingsworth RE et al. ( 2015 ) . Abstract 4162: Interleukin–6 stimulates defective angiogenesis . 4162 - 4162 .
Moore AD, Hodgkinson C, Lapenna A, Zhang F, Witkowska K, Liang Ng F, Headland SE, Reynolds L et al. ( 2014 ) . 203 Hypoxia-inducible Factor-1 Regulates Matrix Metalloproteinase-14 Expression: Underlying Effects of Hypoxia and Statins . Heart . vol. 100 Suppl 3 , A111 - A112 .
Birdsey GM, Shah A, Reynolds L, Almedina MS, Hodiwala-Dilke K, Dejana E, Gerhardt H, Adams RH et al. ( 2014 ) . Regulation of vascular development and angiogenesis by the ETS transcription factor Erg through canonical Wnt signalling . ANGIOGENESIS vol. 17 , ( 1 ) 276 - 277 .
Batista SA, Reynolds L, Tavora B, Hodivala-Dilke K ( 2011 ) . Abstract 517: Deficiency of FAK in the bone marrow compartment enhances tumour metastasis . Cancer Research vol. 71 , ( 8_Supplement ) 517 - 517 .
Reynolds LE, Watson AR, Baker M, Jones TA, D'Amico G, Robinson SD, Joffre C, Garrido-Urbani S et al. ( 2010 ) . Tumour angiogenesis is reduced in the Tc1 mouse model of Downs syndrome . Nature vol. 465 , ( 7299 ) 813 - 817 .
Crossley R, Waddington SN, Howe S, Buckley S, Reynolds L, Sheard V, Gilham D, Hawkins R et al. ( 2008 ) . Gene delivery of latency ablated TGF-beta 3 regulates dermal wound re-epithelialization in mice and reduces factors associated with scar tissue formation . HUMAN GENE THERAPY . vol. 19 , 421 - 421 .
Hodivala-Dilke KM, Reynolds L, Reynolds A, Robinson S, Wyder L, Lively J, Taverna D, Hynes R et al. ( 2006 ) . Evaluating the role of b3-integrins in angiogenesis . FASEB JOURNAL . vol. 20 , A22 - A22 .
Germain M, Silva R, Reynolds L, Robinson S, DiPersio M, Kreidberg J, Georges-Labouesse E, Hodivala-Dilke K ( 2006 ) . Novel roles for integrins in tumour angiogenesis . BREAST CANCER RESEARCH . vol. 8 , S3 - S3 .
McLean GW, Komiyama NH, Serrels B, Asano H, Reynolds L, Conti F, Hodivala-Dilke K, Metzger D et al. ( 2004 ) . Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression . Genes Dev vol. 18 , ( 24 ) 2998 - 3003 .
Hart IR, LEMOINE N, van Trappen P, Crnogorac-Jurcevic T, Reynolds L, Zhu G, Barnes D, Dublin EA et al. ( 2003 ) . Combination of microdissection and microarray analysis to identify gene expression changes between differentially located tumour cells in breast cancer . Oncogene vol. 22 , ( 24 ) 3742 - 3748 .