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Research

Publications: Dr Magdalena Kaneva

Thomas BL, Montero‐Melendez T, Oggero S, Kaneva MK, Chambers D, Pinto AL, Nerviani A, Lucchesi D et al. ( 2024 ) . Molecular Determinants of Neutrophil Extracellular Vesicles That Drive Cartilage Regeneration in Inflammatory Arthritis . Arthritis & Rheumatology vol. 76 , ( 12 ) 1705 - 1718 .
Eldridge S, Barawi A, Thorup AS, Fernandez BF, Bharde S, Sikandar S, Guan Z, Kaneva M et al. ( 2022 ) . AB0156 INTRA-ARTICULAR AGRIN PROVIDES DIRECT PAIN RELIEF IN OSTEOARTHRITIS AND CARTILAGE DEFECTS . Annals of the Rheumatic Diseases vol. 81 , ( Suppl 1 ) 1208.1 - 121208 .
Kaneva MK ( 2022 ) . Neutrophil elastase and its inhibitors-overlooked players in osteoarthritis . FEBS J vol. 289 , ( 1 ) 113 - 116 .
Eldridge S, Barawi A, Wang H, Roelofs A, Kaneva M, Guan Z, Lydon H, Thomas B et al. ( 2021 ) . AB0039 AGRIN REPAIRS BONE AND CARTILAGE IN VIVO . Annals of the Rheumatic Diseases vol. 80 , ( Suppl 1 ) 1052.1 - 101052 .
Kaneva MK, Muley MM, Krustev E, Reid AR, Souza PR, Dell’Accio F, McDougall JJ, Perretti M ( 2021 ) . Alpha‐1‐antitrypsin reduces inflammation and exerts chondroprotection in arthritis . The FASEB Journal vol. 35 , ( 5 )
Rossi S, Maisto R, Gesualdo C, Trotta MC, Ferraraccio F, Kaneva MK, Getting SJ, Surace E et al. ( 2021 ) . Corrigendum to “Activation of Melanocortin Receptors MC1 and MC5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy” . Mediators of Inflammation vol. 2021 , ( 1 )
Eldridge SE, Barawi A, Wang H, Roelofs AJ, Kaneva M, GUAN Z, Lydon H, Thomas B et al. ( 2020 ) . Agrin induces long term osteochondral regeneration by supporting repair morphogenesis . Science Translational Medicine vol. 12 , ( 559 )
Can VC, Locke IC, Kaneva MK, Kerrigan MJP, Merlino F, De Pascale C, Grieco P, Getting SJ ( 2020 ) . Novel anti-inflammatory and chondroprotective effects of the human melanocortin MC1 receptor agonist BMS-470539 dihydrochloride and human melanocortin MC3 receptor agonist PG-990 on lipopolysaccharide activated chondrocytes . European Journal of Pharmacology vol. 872 ,
Kaneva MK, Muley MM, Headland S, De Souza PR, Jones HR, Mori P, Moore A, McDougall JJ et al. ( 2017 ) . AAT – A Novel Cartilage‐Protective Mediator . The FASEB Journal . vol. 31 ,
Kaneva MK, Greco KV, Headland SE, Montero-Melendez T, Mori P, Greenslade K, Pitzalis C, Moore A et al. ( 2017 ) . Identification of Novel Chondroprotective Mediators in Resolving Inflammatory Exudates . The Journal of Immunology vol. 198 , ( 7 ) 2876 - 2885 .
Rossi S, Maisto R, Gesualdo C, Trotta MC, Ferraraccio F, Kaneva MK, Getting SJ, Surace E et al. ( 2016 ) . Activation of Melanocortin Receptors MC1 and MC5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy . Mediators of Inflammation vol. 2016 , ( 1 )
Kaneva MK, Kerrigan MJP, Grieco P, Curley GP, Locke IC, Getting SJ ( 2014 ) . Melanocortin peptides protect chondrocytes from mechanically induced cartilage injury . Biochemical Pharmacology vol. 92 , ( 2 ) 336 - 347 .
Greco KV, Nalesso G, Kaneva MK, Sherwood J, Iqbal AJ, Moradi-Bidhendi N, Dell’Accio F, Perretti M ( 2014 ) . Analyses on the mechanisms that underlie the chondroprotective properties of calcitonin . Biochemical Pharmacology vol. 91 , ( 3 ) 348 - 358 .
Ahmed TJ, Kaneva MK, Pitzalis C, Cooper D, Perretti M ( 2014 ) . Resolution of inflammation: examples of peptidergic players and pathways . Drug Discovery Today vol. 19 , ( 8 ) 1166 - 1171 .
Kaneva MK, Kerrigan MJ, Grieco P, Curley GP, Locke IC, Getting SJ ( 2012 ) . Chondroprotective and anti‐inflammatory role of melanocortin peptides in TNF‐α activated human C‐20/A4 chondrocytes . British Journal of Pharmacology vol. 167 , ( 1 ) 67 - 79 .
Qusous A, Kaneva M, Can VC, Getting SJ, Kerrigan MJP ( 2012 ) . The phenotypic characterization of A13/BACii, a novel bovine chondrocytic cell line with differentiation potential . Cells Tissues Organs vol. 196 , ( 3 ) 251 - 261 .
Kaneva MK, Locke I, Kerrigan M, Getting S ( 2011 ) . A-MSH AND DTRP8-G-MSH INHIBIT PRO-INFLAMMATORY CYTOKINE RELEASE FROM STIMULATED PRIMARY BOVINE CHONDROCYTES . INFLAMMATION RESEARCH . vol. 60 , 279 - 280 .
Getting SJ, Kaneva M, Bhadresa Y, Renshaw D, Leoni G, Patel HB, Kerrigan MJP, Locke IC ( 2009 ) . Melanocortin peptide therapy for the treatment of arthritic pathologies . ScientificWorldJournal vol. 9 , 1394 - 1414 .
Getting SJ, Riffo-Vasquez Y, Pitchford S, Kaneva M, Grieco P, Page CP, Perretti M, Spina D ( 2008 ) . A role for MC3R in modulating lung inflammation . PULM PHARMACOL THER vol. 21 , ( 6 ) 866 - 873 .