Publications: Dr Patricia McGettigan
Adeyeye E, Maniero C, Magavern EF, Ferner RE, McGettigan P
(
2022
)
.
Prescribing direct-acting oral anticoagulants – Mind the evidence gap
.
British Journal of Clinical Pharmacology
vol.
88
,
(
11
)
4724
-
4731
.
Holt A, Strange JE, Rasmussen PV, Blanche P, Nouhravesh N, Jensen MH, Schjerning AM, Schou M et al.
(
2022
)
.
Cardiovascular risk following cannabinoid treatment for patients with chronic pain
.
European Heart Journal
vol.
43
,
(
Supplement_2
)
Holt A, Strange JE, Rasmussen PV, Blanche P, Nouhravesh N, Jensen MH, Schjerning AM, Schou M et al.
(
2022
)
.
Risk of heart failure following short-term non-steroidal anti-inflammatory drug use in patients with type 2 diabetes mellitus
.
European Heart Journal
vol.
43
,
(
Supplement_2
)
Mehta A, Brhlikova P, McGettigan P, Pollock AM, Roderick P, Farooqui HH
(
2022
)
.
Systemic antibiotic sales and WHO recommendations, India
.
Bulletin of the World Health Organization
vol.
100
,
(
10
)
610
-
619
.
Holt A, Strange JE, Nouhravesh N, McGettigan P, Lamberts M
(
2022
)
.
The Reply
.
American Journal of Medicine
vol.
135
,
(
10
)
e407
-
e408
.
Holt A, Blanche P, Georg Jensen AK, Nouhravesh N, Rajan D, Jensen MH, El-Sheikh M, Schjerning AM et al.
(
2022
)
.
Adverse Events Associated With Coprescription of Phosphodiesterase Type 5 Inhibitors and Oral Organic Nitrates in Male Patients With Ischemic Heart Disease A Case-Crossover Study
.
Annals of Internal Medicine
vol.
175
,
(
6
)
774
-
782
.
Holt A, Strange JE, Rasmussen PV, Blanche P, Nouhravesh N, Jensen MH, Schjerning AM, Schou M et al.
(
2022
)
.
Bleeding Risk Following Systemic Fluconazole or Topical Azoles in Patients with Atrial Fibrillation on Apixaban, Rivaroxaban, or Dabigatran
.
American Journal of Medicine
vol.
135
,
(
5
)
595
-
602.e5
.
Morales DR, Moreno-Martos D, Matin N, McGettigan P
(
2022
)
.
Health conditions in adults with HIV compared with the general population: A population-based cross-sectional analysis
.
eClinicalMedicine
vol.
47
,
Holt A, Blanche P, Zareini B, Rasmussen PV, Strange JE, Rajan D, Jensen MH, El-Sheikh M et al.
(
2022
)
.
Gastrointestinal bleeding risk following concomitant treatment with oral glucocorticoids in patients on non-vitamin K oral anticoagulants
.
Heart (British Cardiac Society)
vol.
108
,
(
8
)
626
-
632
.
Holt A, Blanche P, McGettigan P, Lamberts M
(
2022
)
.
Temporal changes in myocardial infarction diagnostic criteria do not account for the lack of long-term beta-blocker effect on cardiovascular prognosis
.
European Heart Journal
vol.
43
,
(
8
)
836
-
838
.
McGettigan P, Morales DR, Moreno-Martos D, Matin N
(
2022
)
.
Changing co-morbidity and increasing deprivation among people living with HIV: UK population-based cross-sectional study
.
HIV Medicine
McGettigan P, Ferner R
(
2022
)
.
We need reliable evidence to guide treatment choices for the many, not the few
.
The BMJ
Holt A, Blanche P, Zareini B, Rasmussen PV, Strange JE, Rajan D, Jensen MH, El-Sheikh M et al.
(
2021
)
.
Gastrointestinal bleeding risk following concomitant treatment with oral glucocorticoids in patients with atrial fibrillation on direct-acting oral anticoagulants
.
European Heart Journal
vol.
42
,
(
Supplement_1
)
Holt A, Blanche P, Jensen AKG, Nouhravesh N, Rajan D, Jensen MH, El-Sheikh M, Schjerning AM et al.
(
2021
)
.
Usage and risk with phosphodiesterase type 5 inhibitors in male patients with chronic ischemic heart disease on oral organic nitrates
.
European Heart Journal
vol.
42
,
(
Supplement_1
)
Jonker CJ, de Vries ST, van den Berg HM, McGettigan P, Hoes AW, Mol PGM
(
2021
)
.
Capturing Data in Rare Disease Registries to Support Regulatory Decision Making: A Survey Study Among Industry and Other Stakeholders
.
Drug Safety
vol.
44
,
(
8
)
853
-
861
.
Holt A, Blanche P, Zareini B, Rajan D, El-Sheikh M, Schjerning AM, Schou M, Torp-Pedersen C et al.
(
2021
)
.
Effect of long-term beta-blocker treatment following myocardial infarction among stable, optimally treated patients without heart failure in the reperfusion era: a Danish, nationwide cohort study
.
European Heart Journal
vol.
42
,
(
9
)
907
-
914
.
Awe E, McGettigan P, Sevcikova P
(
2021
)
.
Surrogates in trials supporting European marketing authorisations of medicines for amyloidosis, cystic fibrosis, hepatitis C and idiopathic pulmonary fibrosis
.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
.
vol.
87
,
1596
-
1596
.
Hodges G, Pallisgaard J, Schjerning Olsen AM, McGettigan P, Andersen M, Krogager M, Kragholm K, Køber L et al.
(
2020
)
.
Association between biomarkers and COVID-19 severity and mortality: A nationwide Danish cohortstudy
.
BMJ Open
vol.
10
,
(
12
)
Holt A, Zareini B, Rajan D, Schou M, Gislason GH, Schjerning AM, McGettigan P, Blanche P et al.
(
2020
)
.
Effect of beta blocker therapy following myocardial infarction in optimally treated patients in the reperfusion era – a Danish, nationwide, and registry-based cohort study
.
European Heart Journal
vol.
41
,
(
Supplement_2
)
Robson J, Moss N, McGettigan P, Beardsley SJ, Lovegrove E, Dezateux C
(
2020
)
.
Editorials: First do no harm: Valproate and medicines safety in pregnancy
.
British Journal of General Practice
vol.
70
,
(
699
)
477
-
478
.
McGettigan P, Ferner RE
(
2020
)
.
Painful perianal ulcers with nicorandil
.
The BMJ
vol.
370
,
Schjerning AM, McGettigan P, Gislason G
(
2020
)
.
Cardiovascular effects and safety of (non-aspirin) NSAIDs
.
Nature Reviews Cardiology
vol.
17
,
(
9
)
574
-
584
.
Schjerning AM, McGettigan P, Gislason GH
(
2020
)
.
Reply to ‘Aspirin as a painkiller in patients with a high cardiovascular risk profile’
.
Nature Reviews Cardiology
vol.
17
,
(
9
)
609
-
610
.
Lovegrove E, Robson J, McGettigan P
(
2020
)
.
Pregnancy protection and pregnancies in women prescribed angiotensin-converting enzyme inhibitors/angiotensin receptor blockers
.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
.
vol.
86
,
1194
-
1194
.
Rashid F, Suresan S, McGettigan P
(
2020
)
.
Prescribing a single inhaler type: Audit of inhaler prescribing in two London general practices
.
BRITISH JOURNAL OF PHARMACOLOGY
.
vol.
177
,
2600
-
2600
.
Lovegrove E, Robson J, McGettigan P
(
2020
)
.
Pregnancy protection and pregnancies in women prescribed ACE inhibitors or ARBs: A cross-sectional study in primary care
.
British Journal of General Practice
vol.
70
,
(
700
)
E778
-
E784
.
Ferner R, McGettigan P
(
2020
)
.
The patient who reports a drug allergy
.
The BMJ
vol.
368
,
McGettigan P, Olmo CA, Plueschke K, Castillon M, Zondag D, Bahri P, Kurz X, Mol PGM
(
2019
)
.
Authors’ Reply to Ravi Jandhyala’s Comment on “Patient Registries: An Underused Resource for Medicines Evaluation: Operational Proposals for Increasing the Use of Patient Registries in Regulatory Assessments”
.
Drug Safety
vol.
42
,
(
12
)
1517
-
1518
.
Schjerning Olsen A-M, Mcgettigan P, Gerds TA, Fosbøl EL, Olesen JB, Sindet-Pedersen C, Staerk L, Hansen ML et al.
(
2019
)
.
Risk of gastrointestinal bleeding associated with oral anticoagulation and non-steroidal anti-inflammatory drugs in patients with atrial fibrillation: a nationwide study
.
European Heart Journal - Cardiovascular Pharmacotherapy
McGettigan P, Alonso Olmo C, Plueschke K, Castillon M, Nogueras Zondag D, Bahri P, Kurz X, Mol PGM
(
2019
)
.
Patient Registries: An Underused Resource for Medicines Evaluation: Operational proposals for increasing the use of patient registries in regulatory assessments
.
Drug Safety
vol.
42
,
(
11
)
1343
-
1351
.
Morales D, Pacurariu A, Slattery J, Pinheiro L, McGettigan P, Kurz X
(
2019
)
.
Association between Peripheral Neuropathy and Exposure to Oral Fluoroquinolone or Amoxicillin-Clavulanate Therapy
.
JAMA Neurology
vol.
76
,
(
7
)
827
-
833
.
McGettigan P, Olmo CA, Plueschke K, Castillon M, Zondag D, Bahri P, Kurz X, Mol P
(
2019
)
.
Improving the use of patient registries in regulatory evaluations
.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
.
vol.
85
,
1652
-
1652
.
Barcella CA, Lamberts M, McGettigan P, Fosbøl EL, Lindhardsen J, Torp-Pedersen C, Gislason GH, Olsen AMS
(
2019
)
.
Differences in cardiovascular safety with non-steroidal anti-inflammatory drug therapy—A nationwide study in patients with osteoarthritis
.
Basic and Clinical Pharmacology and Toxicology
vol.
124
,
(
5
)
629
-
641
.
Olmo CA, McGettigan P, Kurz X
(
2019
)
.
Barriers and Opportunities for Use of Patient Registries in Medicines Regulation
.
Clinical Pharmacology and Therapeutics
vol.
106
,
(
1
)
39
-
42
.
(
2019
)
.
Correction: Electronic healthcare databases in Europe: descriptive analysis of characteristics and potential for use in medicines regulation
.
BMJ Open
vol.
8
,
(
11
)
Morales DR, Slattery J, Pacurariu A, Pinheiro L, McGettigan P, Kurz X
(
2019
)
.
Correction to: Relative and Absolute Risk of Tendon Rupture with Fluoroquinolone and Concomitant Fluoroquinolone/Corticosteroid Therapy: Population-Based Nested Case–Control Study (Clinical Drug Investigation, (2019), 39, 2, (205-213), 10.1007/s40261-018-0729-y)
.
Clinical Drug Investigation
vol.
39
,
(
2
)
Morales DR, Slattery J, Pacurariu A, Pinheiro L, McGettigan P, Kurz X
(
2019
)
.
Relative and Absolute Risk of Tendon Rupture with Fluoroquinolone and Concomitant Fluoroquinolone/Corticosteroid Therapy: Population-Based Nested Case–Control Study
.
Clinical Drug Investigation
vol.
39
,
(
2
)
205
-
213
.
Bruce CS, Brhlikova P, Heath J, McGettigan P
(
2019
)
.
The use of validated and nonvalidated surrogate endpoints in two European Medicines Agency expedited approval pathways: A cross-sectional study of products authorised 2011-2018
.
PLoS Medicine
vol.
16
,
(
9
)
(
2018
)
.
Adverse drug reactions
.
BMJ
vol.
363
,
Morales DR, Slattery J, Pacurariu A, McGettigan P, Kurz X
(
2018
)
.
Association between systemic fluoroquinolone exposure and tendon rupture: Population-based nested case-control study
.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
.
vol.
27
,
339
-
339
.
Plueschke K, McGettigan P, Pacurariu A, Kurz X, Cave A
(
2018
)
.
EU-funded initiatives for real world evidence: Descriptive analysis of their characteristics and relevance for regulatory decision-making
.
BMJ Open
vol.
8
,
(
6
)
McGettigan P, Roderick P, Kadam A, Pollock A
(
2018
)
.
Threats to global antimicrobial resistance control: Centrally approved and unapproved antibiotic formulations sold in India
.
British Journal of Clinical Pharmacology
vol.
85
,
(
1
)
59
-
70
.
Ferner RE, McGettigan P
(
2018
)
.
Adverse drug reactions
.
BMJ (Online)
vol.
363
,
Pacurariu A, Plueschke K, McGettigan P, Morales DR, Slattery J, Vogl D, Goedecke T, Kurz X et al.
(
2018
)
.
Electronic healthcare databases in Europe: Descriptive analysis of characteristics and potential for use in medicines regulation
.
BMJ Open
vol.
8
,
(
9
)
MCGETTIGAN P, Roderick P, Kadam A, Pollock A
(
2017
)
.
Access, Watch, and Reserve antibiotics in India: challenges for WHO stewardship
.
The Lancet Global Health
vol.
5
,
(
11
)
e1075
-
e1076
.
Plueschke K, Kurz X, Cave A, McGettigan P, Pacurariu A
(
2017
)
.
Supporting Pharmacovigilance by Landscaping EU-funded Real World Data
.
DRUG SAFETY
.
vol.
40
,
949
-
949
.
McGettigan P, Olsen AMS
(
2017
)
.
NSAIDs for high-risk patients: none, celecoxib, or naproxen?
.
The Lancet
vol.
389
,
(
10087
)
2351
-
2352
.
McGettigan P, Ferner RE
(
2017
)
.
PCSK9 inhibitors for hypercholesterolaemia
.
BMJ (Online)
vol.
356
,
McGettigan P, McKendree J
(
2016
)
.
Presence of medical students and length of stay in the emergency department
.
JAMA - Journal of the American Medical Association
vol.
315
,
(
18
)
Matin N, Trivedi B, Holyoak H, McGettigan P
(
2016
)
.
Combined HIV/cardiovascular clinic: review of patient cohort and analysis of outcomes
.
HIV MEDICINE
.
vol.
17
,
47
-
47
.
McGettigan P, McKendree J
(
2015
)
.
Interprofessional training for final year healthcare students: A mixed methods evaluation of the impact on ward staff and students of a two-week placement and of factors affecting sustainability Curriculum development
.
BMC Medical Education
vol.
15
,
(
1
)
Olsen AMS, Lindhardsen J, Gislason GH, McGettigan P, Hlatky MA, Fosbøl E, Køber L, Torp-Pedersen C et al.
(
2015
)
.
Impact of proton pump inhibitor treatment on gastrointestinal bleeding associated with non-steroidal anti-inflammatory drug use among post-myocardial infarction patients taking antithrombotics: Nationwide study
.
BMJ (Online)
vol.
351
,
Olsen AMS, Lindhardsen J, Gislason G, McGettigan P, Hlatky M, Koeber L, Torp-Pedersen C, Lamberts M
(
2015
)
.
Impact of PPI treatment on gastrointestinal bleeding associated with NSAID use among post-myocardial infarction patients on antithrombotic therapy - A nationwide study
.
EUROPEAN HEART JOURNAL
.
vol.
36
,
1152
-
1152
.
O'Doherty AM, McGettigan PA
(
2015
)
.
Epigenetic processes in the male germline
.
Reprod Fertil Dev
vol.
27
,
(
5
)
725
-
738
.
McGettigan P, Roderick P, Mahajan R, Kadam A, Pollock AM
(
2015
)
.
Use of Fixed Dose Combination (FDC) Drugs in India: Central Regulatory Approval and Sales of FDCs Containing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), Metformin, or Psychotropic Drugs
.
PLoS Medicine
vol.
12
,
(
5
)
Steele S, Freitag A, McGettigan P, Giovannoni G, Pollock AM
(
2015
)
.
A guide to private prescribing
.
Prescriber
vol.
26
,
(
6
)
19
-
23
.
Olsen AMS, Gislason GH, McGettigan P, Fosbøl E, Sørensen R, Hansen ML, Køber L, Torp-Pedersen C et al.
(
2015
)
.
Association of NSAID use with risk of bleeding and cardiovascular events in patients receiving antithrombotic therapy after myocardial infarction
.
JAMA - Journal of the American Medical Association
vol.
313
,
(
8
)
805
-
814
.
Casey JP, McGettigan PA, Healy F, Hogg C, Reynolds A, Kennedy BN, Ennis S, Slattery D et al.
(
2015
)
.
Unexpected genetic heterogeneity for primary ciliary dyskinesia in the Irish Traveller population
.
Eur J Hum Genet
vol.
23
,
(
2
)
210
-
217
.
Roderick P, Mahajan R, McGettigan P, Pollock AM, Jeffery R
(
2014
)
.
Need for a new drugs bill
.
Economic and Political Weekly
vol.
49
,
(
33
)
15
-
19
.
Conroy J, McGettigan PA, McCreary D, Shah N, Collins K, Parry-Fielder B, Moran M, Hanrahan D et al.
(
2014
)
.
Towards the identification of a genetic basis for Landau-Kleffner syndrome
.
Epilepsia
vol.
55
,
(
6
)
858
-
865
.
Forde N, McGettigan PA, Mehta JP, O'Hara L, Mamo S, Bazer FW, Spencer TE, Lonergan P
(
2014
)
.
Proteomic analysis of uterine fluid during the pre-implantation period of pregnancy in cattle
.
Reproduction
vol.
147
,
(
5
)
575
-
587
.
McGettigan P, Pollock A, Herxheimer A
(
2014
)
.
Department of Health's misguided alert recommending neuraminidase inhibitors for flu
.
BMJ
vol.
348
,
McGettigan P, Pollock A, Herxheimer A
(
2014
)
.
OSELTAMIVIR AND ZANAMIVIR FOR FLU Department of Health's misguided alert recommending neuraminidase inhibitors for flu
.
BMJ-BRITISH MEDICAL JOURNAL
vol.
348
,
Article
ARTN g1594
,
Roderick P, Mahajan R, McGettigan P, Pollock AM
(
2014
)
.
India should introduce a new Drugs Act
.
Lancet
vol.
383
,
(
9913
)
203
-
206
.
Herxheimer A, McGettigan P
(
2013
)
.
Problems of polypharmacy
.
BMJ
vol.
347
,
McGettigan P, Henry D
(
2013
)
.
Use of NSAIDs with Increased Risk of Cardiovascular Events in Low and Middle Income Countries
.
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
vol.
22
,
423
-
423
.
Forde N, Mehta JP, McGettigan PA, Mamo S, Bazer FW, Spencer TE, Lonergan P
(
2013
)
.
Alterations in expression of endometrial genes coding for proteins secreted into the uterine lumen during conceptus elongation in cattle
.
BMC Genomics
vol.
14
,
McGettigan P, McKendree J, Reed N, Holborow S, Walsh CD, Mace T
(
2013
)
.
Identifying attributes required by Foundation Year 1 doctors in multidisciplinary teams: a tool for performance evaluation
.
BMJ Qual Saf
vol.
22
,
(
3
)
225
-
232
.
Pollock AM, Brhlikova P, McGettigan P
(
2013
)
.
Reviewers commentary on Should oral misoprostol be used to prevent postpartum haemorrhage in home-birth settings in low-resource countries? A systematic review of the evidence
.
BJOG: An International Journal of Obstetrics and Gynaecology
vol.
120
,
(
3
)
McGettigan PA
(
2013
)
.
Transcriptomics in the RNA-seq era
.
Curr Opin Chem Biol
vol.
17
,
(
1
)
4
-
11
.
McGettigan P, Henry D
(
2013
)
.
Use of non-steroidal anti-inflammatory drugs that elevate cardiovascular risk: an examination of sales and essential medicines lists in low-, middle-, and high-income countries
.
PLoS Med
vol.
10
,
(
2
)
Pluta K, McGettigan PA, Reid CJ, Browne JA, Irwin JA, Tharmalingam T, Corfield A, Baird A et al.
(
2012
)
.
Molecular aspects of mucin biosynthesis and mucus formation in the bovine cervix during the periestrous period
.
Physiol Genomics
vol.
44
,
(
24
)
1165
-
1178
.
Mullen MP, Creevey CJ, Berry DP, McCabe MS, Magee DA, Howard DJ, Killeen AP, Park SD et al.
(
2012
)
.
Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples
.
BMC Genomics
vol.
13
,
McGettigan P, Lincz LF, Attia J, McElduff P, Bissett L, Peel R, Stokes B, Hancock S et al.
(
2011
)
.
The risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors does not vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene
.
BRIT J CLIN PHARMACO
vol.
72
,
(
4
)
707
-
714
.
McGettigan P, Henry D
(
2011
)
.
Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies
.
PLoS Med
vol.
8
,
(
9
)
McGettigan P, Henry D
(
2011
)
.
Cardiovascular Events after Prescription of NSAIDs - Updated Systematic Review of Pharmaco-Epidemiological Studies
.
PHARMACOEPIDEM DR S
vol.
20
,
S324
-
S325
.
Waring WS, McGettigan P
(
2011
)
.
Clinical toxicology and drug regulation: A United Kingdom perspective
.
CLIN TOXICOL
vol.
49
,
(
6
)
452
-
456
.
McGettigan P, Henry D
(
2011
)
.
EVALUATION OF CARDIOVASCULAR RISK WITH NSAIDS: LIMITATIONS ARISING FROM INCONSISTENT REPORTING IN PHARMACOEPIDEMIOLOGICAL STUDIE
.
BASIC CLIN PHARMACOL
vol.
109
,
139
-
139
.
McGettigan P, Henry D
(
2011
)
.
PHARMACOEPIDEMIOLOGICAL STUDIES ADVANCE THE INFORMATION FROM RANDOMIZED TRIALS INVESTIGATING NSAID ASSOCIATED CARDIOVASCULAR RISK
.
BASIC CLIN PHARMACOL
vol.
109
,
25
-
25
.
McGivney BA, McGettigan PA, Browne JA, Evans ACO, Fonseca RG, Loftus BJ, Lohan A, MacHugh DE et al.
(
2010
)
.
Characterization of the equine skeletal muscle transcriptome identifies novel functional responses to exercise training
.
BMC Genomics
vol.
11
,
O'Sullivan NC, Croydon L, McGettigan PA, Pickering M, Murphy KJ
(
2010
)
.
Hippocampal region-specific regulation of NF-kappaB may contribute to learning-associated synaptic reorganisation
.
Brain Res Bull
vol.
81
,
(
4-5
)
385
-
390
.
Edwards CJ, Magee DA, Park SDE, McGettigan PA, Lohan AJ, Murphy A, Finlay EK, Shapiro B et al.
(
2010
)
.
A complete mitochondrial genome sequence from a mesolithic wild aurochs (Bos primigenius)
.
PLoS One
vol.
5
,
(
2
)
Henry D, Lincz L, Attia J, McElduff P, Bisset L, Peel R, Hancock S, Henderson K et al.
(
2009
)
.
POLYMORPHISMS IN TWO REGIONS OF THE CYCLO-OXYGENASE-2 GENE ASSOCIATED WITH VARIATION IN RISK OF CORONARY THROMBOSIS WITH CYCLO-OXYGENASE-2 INHIBITORS
.
BASIC CLIN PHARMACOL
vol.
105
,
39
-
39
.
Henry D, Lincz L, Attia J, McElduff P, Bisset L, Peel R, Hancock S, Henderson K et al.
(
2009
)
.
Polymorphisms in Two Regions of the Cyclo-Oxygenase-2 Gene Associated with Variation in Risk of Coronary Thrombosis with Cyclo-Oxygenase-2 Inhibitors
.
PHARMACOEPIDEM DR S
vol.
18
,
S116
-
S116
.
McGettigan P, Dakkak E, Morris I
(
2009
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