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  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Aoife Murray

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Murray A, Muñiz-García A, Alić I, Nižetić D ( 2024 ) . It’s good to know what to BACE the specificity of your inhibitors on . Journal of Clinical Investigation vol. 134 , ( 16 )
Fertan E, Böken D, Murray A, Danial JSH, Lam JYL, Wu Y, Goh PA, Alić I et al. ( 2023 ) . Cerebral organoids with chromosome 21 trisomy secrete Alzheimer’s disease-related soluble aggregates detectable by single-molecule-fluorescence and super-resolution microscopy . Molecular Psychiatry vol. 29 , ( 2 ) 369 - 386 .
Murray A, Gough G, Cindrić A, Vučković F, Koschut D, Borelli V, Petrović DJ, Bekavac A et al. ( 2023 ) . Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels . EBioMedicine vol. 94 ,
Alić I, Goh PA, Murray A, Portelius E, Gkanatsiou E, Gough G, Mok KY, Koschut D et al. ( 2021 ) . Correction: Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain . Molecular Psychiatry vol. 26 , ( 10 ) 5789 - 5789 .
Alic I, Goh P, Murray A, Portelius E, Gough G, Gkanatsiou E, Wallon D, Rovelet‐Lecrux A et al. ( 2020 ) . Alzheimer‐like pathology in trisomy 21 cerebral organoids amenable to pharmacological inhibition reveals BACE2 as a gene‐dose‐sensitive AD‐suppressor in human brain . Alzheimer's & Dementia vol. 16 , ( S2 )
Alić I, Goh PA, Murray A, Portelius E, Gkanatsiou E, Gough G, Mok KY, Koschut D et al. ( 2020 ) . Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain . Molecular Psychiatry vol. 26 , ( 10 ) 5766 - 5788 .
Zhang K, Chooi WH, Liu S, Chin JS, Murray A, Nizetic D, Cheng D, Chew SY ( 2020 ) . Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering . Biomaterials vol. 256 ,
Gough G, O'Brien NL, Alic I, Goh PA, Yeap YJ, Groet J, Nizetic D, Murray A ( 2019 ) . Chapter 3 Modeling Down syndrome in cells: From stem cells to organoids . Preclinical Research in Down Syndrome: Insights for Pathophysiology and Treatments , vol. 251 , Elsevier
Chooi WH, Ong W, Murray A, Lin J, Nizetic D, Chew SY ( 2019 ) . Correction: Scaffold mediated gene knockdown for neuronal differentiation of human neural progenitor cells . Biomaterials Science vol. 7 , ( 6 ) 2623 - 2623 .
Chooi WH, Ong W, Murray A, Lin J, Nizetic D, Chew SY ( 2018 ) . Scaffold mediated gene knockdown for neuronal differentiation of human neural progenitor cells . Biomaterials Science vol. 6 , ( 11 ) 3019 - 3029 .
Murray A, Goh P, Yeap Y, Startin C, Hamburg S, Hithersay R, d'Souza H, Mok K et al. ( 2017 ) . [P3–168]: GENETIC DISSECTION OF SEVERITY AND ONSET MODULATORS FOR ALZHEIMER's PATHOLOGY IN DOWN SYNDROME USING CELLULAR SYSTEMS . Alzheimer's & Dementia vol. 13 , ( 7S_Part_20 ) p998 - p999 .
Murray A, Letourneau A, Canzonetta C, Stathaki E, Gimelli S, Sloan-Bena F, Abrehart R, Goh P et al. ( 2015 ) . Brief Report: Isogenic Induced Pluripotent Stem Cell Lines From an Adult With Mosaic Down Syndrome Model Accelerated Neuronal Ageing and Neurodegeneration . STEM CELLS vol. 33 , ( 6 ) 2077 - 2084 .
Goh P, Murray A, Rovelet-Lecrux A, Wallon D, Karmiloff-Smith A, Hardy J, Strydom A, Groet J et al. ( 2015 ) . MODELLING NEURAL PATHOLOGY AND DEMENTIA IN DOWN SYNDROME USING INDUCED PLURIPOTENT STEM CELLS . JOURNAL OF INTELLECTUAL DISABILITY RESEARCH vol. 59 , ( 9 ) 790 - 790 .
Nikolaev SI, Garieri M, Santoni F, Falconnet E, Ribaux P, Guipponi M, Murray A, Groet J et al. ( 2014 ) . Frequent cases of RAS-mutated Down syndrome acute lymphoblastic leukaemia lack JAK2 mutations . Nature Communications vol. 5 , ( 1 )
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