Publications: Dr John Prowle

Azzopardi G, Prowle J ( 2024 ) . Acute Kidney Disease . Nutrition, Metabolism and Kidney Support , Springer Nature

Vickery NJ, Fowler AJ, Prowle J, Pearse R ( 2024 ) . Association between multimorbidity and quality of life after hip replacement surgery: analysis of routinely collected patient-reported outcomes . British Journal of Anaesthesia

Murugan R, Prowle J, Beaubien-Souligny W ( 2024 ) . Protocolized fluid balance neutralization during continuous renal replacement therapy . Intensive Care Medicine vol. 50 , ( 12 ) 2141 - 2143 .

Haines RW, Granholm A, Puthucheary Z, Day AG, Bear DE, Prowle JR, Heyland DK ( 2024 ) . The effect of high protein dosing in critically ill patients: an exploratory, secondary Bayesian analyses of the EFFORT Protein trial . British Journal of Anaesthesia vol. 133 , ( 6 ) 1192 - 1200 .

Azzopardi G, Mekhaimar A, Haines RW, Stephens TJ, Puthucheary Z, Prowle JR ( 2024 ) . Clinician assessment of kidney function from plasma creatinine values during critical illness: A scenario-based international multi-professional survey . Journal of Critical Care vol. 85 ,

Zarbock A, Forni LG, Koyner JL, Bell S, Reis T, Meersch M, Bagshaw SM, Fuhmann DY et al. ( 2024 ) . Recommendations for clinical trial design in acute kidney injury from the 31st acute disease quality initiative consensus conference. A consensus statement . Intensive Care Medicine vol. 50 , ( 9 ) 1426 - 1437 .

Kellum JA, Bagshaw SM, Demirjian S, Forni L, Joannidis M, Kampf JP, Koyner JL, Kwan T et al. ( 2024 ) . CCL14 testing to guide clinical practice in patients with AKI: Results from an international expert panel . Journal of Critical Care vol. 82 ,

Koyner JL, Arndt C, de Irujo JBM, Coelho S, de la Peña MG-M, di Girolamo L, Joannidis M, Jorge-Monjas P et al. ( 2024 ) . Assessing the role of Chemokine (C–C motif) ligand 14 in AKI: a European consensus meeting . Renal Failure vol. 46 , ( 1 )

Bellomo R, Ankawi G, Bagshaw SM, Baldwin I, Basu R, Bottari G, Cantaluppi V, Clark W et al. ( 2024 ) . Hemoadsorption: consensus report of the 30th Acute Disease Quality Initiative workgroup . Nephrology Dialysis Transplantation vol. 39 , ( 12 ) 1945 - 1964 .

Davies TW, Watson N, Pilkington JJ, McClelland TJ, Azzopardi G, Pearse RM, Prowle J, Puthucheary Z ( 2024 ) . Creatine supplementation for optimization of physical function in the patient at risk of functional disability: A systematic review and meta‐analysis . Journal of Parenteral and Enteral Nutrition vol. 48 , ( 4 ) 389 - 405 .

Prowle JR, Croal B, Abbott TEF, Cuthbertson BH, Wijeysundera DN, Myles PS, Shulman MA, Wallace S et al. ( 2024 ) . Cystatin C or creatinine for pre-operative assessment of kidney function and risk of post-operative acute kidney injury: a secondary analysis of the METS cohort study . Clinical Kidney Journal vol. 17 , ( 1 )

Haines RW, Prowle JR, Day A, Bear DE, Heyland DK, Puthucheary Z ( 2024 ) . Association between urea trajectory and protein dose in critically ill adults: a secondary exploratory analysis of the effort protein trial (RE-EFFORT) . Critical Care vol. 28 , ( 1 )

Bellomo R, Mehta RL, Forni LG, Zarbock A, Ostermann M, Ronco C ( 2024 ) . Hemoadsorption . Clinical Journal of the American Society of Nephrology vol. 19 , ( 6 ) 803 - 806 .

Prowle JR, Bagshaw SM, Forni LG ( 2024 ) . Tackling sepsis-associated AKI: are there any chances of REVIVAL with new approaches? . Intensive Care Medicine vol. 50 , ( 1 ) 131 - 133 .

Page A, Langan A, Wan YI, McNelly A, Prowle J, Pearse R, Puthucheary Z ( 2023 ) . Association between energy surplus and intensive care unit length of stay in critically ill patients: A retrospective cohort study . Journal of Parenteral and Enteral Nutrition vol. 48 , ( 2 ) 206 - 214 .

McNelly A, Langan A, Bear DE, Page A, Martin T, Seidu F, Santos F, Rooney K et al. ( 2023 ) . A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed . Nat Commun vol. 14 , ( 1 )

Ludwiczak A, Stephens TJ, Prowle J, Pearse R, Osman M ( 2023 ) . Supporting effective shared decision‐making in surgical context: Why framing of choices matters for high‐risk patients and clinicians . Colorectal Disease vol. 26 , ( 1 ) 110 - 119 .

Davies TW, Kelly E, van Gassel RJJ, van de Poll MCG, Gunst J, Casaer MP, Christopher KB, Preiser JC et al. ( 2023 ) . A systematic review and meta-analysis of the clinimetric properties of the core outcome measurement instruments for clinical effectiveness trials of nutritional and metabolic interventions in critical illness (CONCISE) . Critical Care vol. 27 , ( 1 )

Ostermann M, Ankawi G, Cantaluppi V, Madarasu R, Dolan K, Husain-Syed F, Kashani K, Mehta R et al. ( 2023 ) . Nomenclature of Extracorporeal Blood Purification Therapies for Acute Indications: The Nomenclature Standardization Conference . Blood Purification vol. 53 , ( 5 ) 358 - 372 .

Matsumoto K, Malcolm H, Thomson W, Osman M, Puthucheary Z, Prowle J, Stephens T ( 2023 ) . Determining influences on ventilatory decision-making in COVID-19 ARDS . Conference: Acute critical care

Russo G, Harrois A, Anstey J, Van Der Jagt M, Taccone F, Udy A, Citerio G, Duranteau J et al. ( 2023 ) . Early sedation in traumatic brain injury: a multicentre international observational study . Critical Care and Resuscitation vol. 24 , ( 4 ) 319 - 329 .

Toal CM, Fowler AJ, Patel BV, Puthucheary Z, Prowle JR ( 2023 ) . Hypoxemia Trajectory of Non-COVID-19 Acute Respiratory Distress Syndrome Patients. An Observational Study Focusing on Hypoxemia Resolver Status . Critical Care Explorations vol. 5 , ( 10 )

Eldridge JC, Shah AB, Lucena-Amaro S, Kirwan CJ, Prowle JR, Wan YI ( 2023 ) . Dynamic dosing for continuous renal replacement therapy: Service evaluation of the safety and effectiveness of titrating dose to biochemistry . Journal of the Intensive Care Society vol. 25 , ( 1 ) 50 - 58 .

Zarbock A, Koyner JL, Gomez H, Pickkers P, Forni L, Nadim MK, Bell S, Joannidis M et al. ( 2023 ) . Sepsis-associated acute kidney injury—treatment standard . Nephrology Dialysis Transplantation vol. 39 , ( 1 ) 26 - 35 .

Fowler AJ, Wahedally MAH, Abbott TEF, Prowle JR, Cromwell DA, Pearse RM ( 2023 ) . Long-term disease interactions amongst surgical patients: a population cohort study . British Journal of Anaesthesia vol. 131 , ( 2 ) 407 - 417 .

Fowler AJ, Brayne AB, Pearse RM, Prowle JR ( 2023 ) . Long-term healthcare use after postoperative complications: an analysis of linked primary and secondary care routine data . BJA Open vol. 7 ,

Eldridge JC, Wan YI, Prowle JR ( 2023 ) . Hemoperfusion in Trauma . Contributions to Nephrology vol. 200 , 169 - 179 .

Haines RW, Fowler AJ, Liang K, Pearse RM, Larsson AO, Puthucheary Z, Prowle JR ( 2023 ) . Comparison of Cystatin C and Creatinine in the Assessment of Measured Kidney Function during Critical Illness . Clinical Journal of the American Society of Nephrology vol. 18 , ( 8 ) 997 - 1005 .

Liu S-Y, Xu S-Y, Yin L, Yang T, Jin K, Zhang Q-B, Sun F, Tan D-Y et al. ( 2023 ) . Management of regional citrate anticoagulation for continuous renal replacement therapy: guideline recommendations from Chinese emergency medical doctor consensus . Military Medical Research vol. 10 , ( 1 )

Wan YI, Puthucheary ZA, Pearse RM, Prowle JR ( 2023 ) . Characterising biological mechanisms underlying ethnicity-associated outcomes in COVID-19 through biomarker trajectories: a multicentre registry analysis . British Journal of Anaesthesia vol. 131 , ( 3 ) 491 - 502 .

Prowle JR, Artigas A, Bagshaw SM, Forni LG, Heung M, Hoste E, Marlies O, Koyner JL et al. ( 2023 ) . Serial Urinary C-C Motif Chemokine Ligand 14 and Risk of Persistent Severe Acute Kidney Injury . Critical Care Explorations vol. 5 , ( 3 ) E0870 - E0870 .

Zarbock A, Nadim MK, Pickkers P, Gomez H, Bell S, Joannidis M, Kashani K, Koyner JL et al. ( 2023 ) . Sepsis-associated acute kidney injury: consensus report of the 28th Acute Disease Quality Initiative workgroup . Nature Reviews Nephrology vol. 19 , ( 6 ) 401 - 417 .

McClelland TJ, Fowler AJ, Davies TW, Pearse R, Prowle J, Puthucheary Z ( 2023 ) . Can pioglitazone be used for optimization of nutrition in critical illness? A systematic review . Journal of Parenteral and Enteral Nutrition vol. 47 , ( 4 ) 459 - 475 .

Fowler AJ, Brayne A, Pearse RM, Prowle JR ( 2023 ) . Long-term healthcare use after postoperative complications: a prospective analysis of linked primary and secondary care routine data .

Jackson AIR, Boney O, Pearse RM, Kurz A, Cooper DJ, van Klei WA, Cabrini L, Miller TE et al. ( 2023 ) . Systematic reviews and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: mortality, morbidity, and organ failure . British Journal of Anaesthesia vol. 130 , ( 4 ) 404 - 411 .

Fazzini B, Märkl T, Costas C, Blobner M, Schaller SJ, Prowle J, Puthucheary Z, Wackerhage H ( 2023 ) . The rate and assessment of muscle wasting during critical illness: a systematic review and meta-analysis . Critical Care vol. 27 , ( 1 )

Azzopardi G, Prowle J ( 2023 ) . Biochemical estimation of muscle mass and unbiased assessment of kidney function using serum creatinine and cystatin-C: A prognostic validation study within UK Biobank .

Barton J, Bien Z, Prowle J, Wan Y ( 2023 ) . COVID-19 Associated Acute Kidney Injury: Long Term Outcomes (Statistical Analysis Plan) .

Toal CM, Fowler AJ, Pearse RM, Puthucheary Z, Prowle JR, Wan YI ( 2022 ) . Health Resource Utilisation and Disparities: an Ecological Study of Admission Patterns Across Ethnicity in England Between 2017 and 2020 . Journal of Racial and Ethnic Health Disparities vol. 10 , ( 6 ) 2872 - 2881 .

Rubulotta F, Brett S, Boulanger C, Blackwood B, Deschepper M, Labeau SO, Blot S, Infirmary AR et al. ( 2022 ) . Prevalence of skin pressure injury in critical care patients in the UK: results of a single-day point prevalence evaluation in adult critically ill patients . BMJ Open vol. 12 , ( 11 )

Matsumoto K, Prowle JR ( 2022 ) . COVID-19-associated AKI . Current Opinion in Critical Care vol. 28 , ( 6 ) 630 - 637 .

Fowler AJ, Trivedi B, Boomla K, Pearse R, Prowle J ( 2022 ) . Change in healthcare utilisation after surgical treatment: observational study of routinely collected patient data from primary and secondary care . British Journal of Anaesthesia vol. 129 , ( 6 ) 889 - 897 .

Boyer N, Eldridge J, Prowle JR, Forni LG ( 2022 ) . Postoperative Acute Kidney Injury . Clinical Journal of the American Society of Nephrology vol. 17 , ( 10 ) 1535 - 1545 .

Fowler A, Wan Y, Prowle J, Pearse R, ABBOTT T ( 2022 ) . Long-term mortality following complications after elective surgery: a secondary analysis of pooled data from two prospective cohort studies . British Journal of Anaesthesia

Davies TW, van Gassel RJJ, van de Poll M, Gunst J, Casaer MP, Christopher KB, Preiser JC, Hill A et al. ( 2022 ) . Core outcome measures for clinical effectiveness trials of nutritional and metabolic interventions in critical illness: an international modified Delphi consensus study evaluation (CONCISE) . Critical Care vol. 26 , ( 1 )

Wan YI, Apea VJ, Dhairyawan R, Puthucheary ZA, Pearse RM, Orkin CM, Prowle JR ( 2022 ) . Ethnic disparities in hospitalisation and hospital-outcomes during the second wave of COVID-19 infection in east London . Scientific Reports vol. 12 , ( 1 )

Haines RW, Fowler AJ, Wan YI, Flower L, Heyland DK, Day A, Pearse RM, Prowle JR et al. ( 2022 ) . Catabolism in Critical Illness: A Reanalysis of the REducing Deaths due to OXidative Stress (REDOXS) Trial . Crit Care Med

Ahmed WUR, Bhatia S, McLean KA, Khaw R, Baker D, Kamarajah SK, Bell S, Nepogodiev D et al. ( 2022 ) . Validation of the OAKS prognostic model for acute kidney injury after gastrointestinal surgery . BJS Open vol. 6 , ( 1 )

Bien Z, Fowler AJ, Robbins AJ, Pearse RM, Prowle JR, Wan YI ( 2022 ) . Trends in Hospital Admissions Associated with an Acute Kidney Injury in England 1998–2020: a Repeated Cross-Sectional Study . SN Comprehensive Clinical Medicine vol. 4 , ( 1 ) 53 - 53 .

Subramaniam A, Anstey C, Curtis JR, Ashwin S, Ponnapa Reddy M, Aliberti MJR, Avelino-Silva TJ, Welch C et al. ( 2022 ) . Characteristics and Outcomes of Patients With Frailty Admitted to ICU With Coronavirus Disease 2019: An Individual Patient Data Meta-Analysis . Critical Care Explorations vol. 4 , ( 1 )

McLean KA, Kamarajah SK, Mills E, Glasbey JC, Nepogodiev D, Glasbey JC, Borakati A, Burke J et al. ( 2022 ) . Impact of postoperative acute kidney injury in patients undergoing major gastrointestinal surgery on 1-year survival and renal outcomes: a national multicentre cohort study . BJS Open vol. 5 , ( 6 )

Fowler AJ, Wahedally MAH, Abbott TEF, Smuk M, Prowle JR, Pearse RM, Cromwell DA ( 2021 ) . Death after surgery among patients with chronic disease: prospective study of routinely collected data in the English NHS . British journal of anaesthesia vol. 128 , ( 2 ) 333 - 342 .

Tarazona V, Figueiredo S, Hamada S, Pochard J, Haines RW, Prowle JR, Duranteau J, Vigué B et al. ( 2021 ) . Admission serum myoglobin and the development of acute kidney injury after major trauma . Annals of Intensive Care vol. 11 , ( 1 )

Flower L, Haines RW, McNelly A, Bear DE, Koelfat K, Damink SO, Hart N, Montgomery H et al. ( 2021 ) . The effect of intermittent or continuous feeding and amino acid concentration on urea-to-creatinine ratio in critical illness . JPEN J Parenter Enteral Nutr

Wan YI, Robbins AJ, Apea VJ, Orkin CM, Pearse R, Puthucheary ZA, Prowle JR ( 2021 ) . Ethnicity and acute hospital admissions: Multi-center analysis of routine hospital data . EClinicalMedicine101077 - 101077 .

Wan YI, Apea VJ, Dhairyawan R, Puthucheary ZA, Pearse RM, Orkin CM, Prowle JR ( 2021 ) . Ethnic disparities in hospitalisation and hospital-outcomes during the second wave of COVID-19 infection in east London . medrxiv

Maniero C, Patel D, Pavithran A, Naran P, Ng FL, Prowle J, Sivapathasuntharam D ( 2021 ) . A retrospective cohort study of risk factors and outcomes in older patients admitted to an inner-city geriatric unit in London during first peak of COVID-19 pandemic . Irish Journal of Medical Science vol. 191 , ( 3 ) 1037 - 1045 .

Pickkers P, Darmon M, Hoste E, Joannidis M, Legrand M, Ostermann M, Prowle JR, Schneider A et al. ( 2021 ) . Acute kidney injury in the critically ill: an updated review on pathophysiology and management . Intensive Care Medicine vol. 47 , ( 8 ) 835 - 850 .

Fronczek J, Polok K, de Lange DW, Jung C, Beil M, Rhodes A, Fjølner J, Górka J et al. ( 2021 ) . Relationship between the Clinical Frailty Scale and short-term mortality in patients ≥ 80 years old acutely admitted to the ICU: a prospective cohort study . Critical Care vol. 25 , ( 1 )

Patel BV, Haar S, Handslip R, Auepanwiriyakul C, Lee TM-L, Patel S, Harston JA, Hosking-Jervis F et al. ( 2021 ) . Natural history, trajectory, and management of mechanically ventilated COVID-19 patients in the United Kingdom . Intensive Care Medicine

Prowle JR, Forni LG, Bell M, Chew MS, Edwards M, Grams ME, Grocott MPW, Liu KD et al. ( 2021 ) . Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative . Nature Reviews Nephrology

Page A, Flower L, Prowle J, Puthucheary Z ( 2021 ) . Novel methods to identify and measure catabolism . Current Opinion in Critical Care vol. Publish Ahead of Pri ,

Törnblom S, Wiersema R, Prowle JR, Haapio M, Pettilä V, Vaara ST ( 2021 ) . Fluid balance -adjusted creatinine in diagnosing Acute Kidney Injury in the critically ill . Acta Anaesthesiol Scand

Vaara ST, Ostermann M, Bitker L, Schneider A, Poli E, Hoste E, Fierens J, Joannidis M et al. ( 2021 ) . Restrictive fluid management versus usual care in acute kidney injury (REVERSE-AKI): a pilot randomized controlled feasibility trial . Intensive Care Medicine vol. 47 , ( 6 ) 665 - 673 .

Crocker-Buque T, Williams S, Brentnall AR, Gabe R, Duffy S, Prowle JR, Orkin C, Kunst H et al. ( 2021 ) . The Barts Health NHS Trust COVID-19 cohort: characteristics, outcomes and risk scoring of patients in East London . The International Journal of Tuberculosis and Lung Disease vol. 25 , ( 5 ) 358 - 366 .

Wan YI, Bien Z, Apea VJ, Orkin CM, Dhairyawan R, Kirwan CJ, Pearse RM, Puthucheary ZA et al. ( 2021 ) . Acute Kidney Injury in COVID-19: multicentre prospective analysis of registry data . Clinical Kidney Journalsfab071- - sfab071- .

Deschepper M, Labeau SO, Waegeman W, Blot SI, Team TDS, collaborators TESOICMTG ( 2021 ) . Pressure injury prediction models for critically-ill patients should consider both the case-mix and local factors . Intensive and Critical Care Nursing vol. 65 ,

Robbins AJ, Fowler AJ, Haines RW, Pearse RM, Prowle JR, Puthucheary Z ( 2021 ) . Emergency hospital admissions associated with non-communicable diseases 1998-2018 in England, Wales and Scotland: an ecological study . Clinical Medicine vol. 21 , ( 2 ) e179 - e185 .

Prowle J, Mehta R ( 2021 ) . Fluid balance management during continuous renal replacement therapy . Seminars in Dialysis vol. 34 , ( 6 ) 440 - 448 .

Labeau SO, Afonso E, Benbenishty J, Blackwood B, Boulanger C, Brett SJ, Calvino-Gunther S, Chaboyer W et al. ( 2021 ) . Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study . Intensive Care Medicine vol. 47 , ( 2 ) 160 - 169 .

Apea VJ, Wan YI, Dhairyawan R, Puthucheary ZA, Pearse RM, Orkin CM, Prowle JR ( 2021 ) . Ethnicity and outcomes in patients hospitalised with COVID-19 infection in East London: an observational cohort study . BMJ Open vol. 11 , ( 1 ) e042140 - e042140 .

Prowle J, Wan Y, Bien Z ( 2021 ) . Acute Kidney Injury in COVID-19: secondary analysis of prospective data from the EthICAL study .

Wan Y, Puthucheary Z, Prowle J ( 2021 ) . Comorbid disease and ethnicity in emergency hospital admissions in east London .

Nadim MK, Forni LG, Mehta RL, Connor MJ, Liu KD, Ostermann M, Rimmelé T, Zarbock A et al. ( 2020 ) . COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup . Nat Rev Nephrol vol. 16 , ( 12 ) 747 - 764 .

Chan C-K, Chi C-Y, Lai T-S, Huang T-M, Chou N-K, Huang Y-P, Prowle JR, Wu V-C et al. ( 2020 ) . Long-term outcomes following vehicle trauma related acute kidney injury requiring renal replacement therapy: a nationwide population study . Scientific Reports vol. 10 , ( 1 )

Wan YI, McGuckin D, Fowler AJ, Prowle JR, Pearse RM, Moonesinghe SR ( 2020 ) . Socioeconomic deprivation and long-term outcomes after elective surgery: analysis of prospective data from two observational studies . British Journal of Anaesthesia

Wan YI, Brayne AB, Haines RW, Puthucheary ZA, Prowle JR ( 2020 ) . Prognostic association of routinely measured biomarkers in patients admitted to critical care: a systematic review . Biomarkers1 - 12 .

Beattie WS, Lalu M, Bocock M, Feng S, Wijeysundera DN, Nagele P, Fleisher LA, Kurz A et al. ( 2020 ) . Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes . British Journal of Anaesthesia

Ostermann M, Zarbock A, Goldstein S, Kashani K, Macedo E, Murugan R, Bell M, Forni L et al. ( 2020 ) . Recommendations on Acute Kidney Injury Biomarkers From the Acute Disease Quality Initiative Consensus Conference: A Consensus Statement . JAMA Network Open vol. 3 , ( 10 ) e2019209 - e2019209 .

Harrois A, Anstey JR, van der Jagt M, Taccone FS, Udy AA, Citerio G, Duranteau J, Ichai C et al. ( 2020 ) . Variability in Serum Sodium Concentration and Prognostic Significance in Severe Traumatic Brain Injury: A Multicenter Observational Study . Neurocritical Care

Ferrada P, Strumwasser A, Zarbock A, Mackey C, Wilkinson J, Handisides D, Prowle J ( 2020 ) . EFFECT OF ANGIOTENSIN II ON VASOPRESSOR DOSE AND SAFETY IN PATIENTS WITH SEVERE VASODILATORY SHOCK . CRITICAL CARE MEDICINE . Conference: SCCM from: 04/07/2020 to: 04/07/2020 , vol. 47 ,

Wilk M, Marsh DW, de Freitas S, Prowle J ( 2020 ) . Predicting length of stay in hospital using electronic records available at the time of admission . Studies in Health Technology and Informatics vol. 270 , 377 - 381 .

Apea V, Wan Y, Dhairyawan R, Puthucheary Z, Pearse R, Orkin C, Prowle J ( 2020 ) . Ethnicity and outcomes in patients hospitalised with COVID-19 infection in East London: an observational cohort study . medrxiv

Mcnelly AS, Flower L, Stevens TJ, Fowler AJ, Pearse RM, Prowle J, Puthucheary ZA ( 2020 ) . Attitudes of multimorbid patients to surviving future acute illness and subsequent functional disability: A systematic review . medRxiv2020.06.03.20121293 - 2020.06.03.20121293 .

Wan Y, Apea V, Dhairyawan R, Orkin C, Pearse RM, Prowle JR ( 2020 ) . ETHICAL: Ethnic Disparities In COVID-19 Admissions in east London .

Shaw S, Hughes G, Stephens T, Pearse R, Prowle J, Ashcroft RE, Avagliano E, Day J et al. ( 2020 ) . Understanding decision making about major surgery: protocol for a qualitative study of shared decision making by high-risk patients and their clinical teams . BMJ open vol. 10 , ( 5 ) e033703 - e033703 .

Wang D, Yin Y, Hu C, Liu X, Zhang X, Zhou S, Jian M, Xu H et al. ( 2020 ) . Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China . Critical Care (UK) vol. 24 , ( 1 )

Ostermann M, Bellomo R, Burdmann EA, Doi K, Endre ZH, Goldstein SL, Kane-Gill SL, Liu KD et al. ( 2020 ) . Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference . Kidney International vol. 98 , ( 2 ) 294 - 309 .

Hoste E, Bihorac A, Al-Khafaji A, Ortega LM, Ostermann M, Haase M, Zacharowski K, Wunderink R et al. ( 2020 ) . Identification and validation of biomarkers of persistent acute kidney injury: the RUBY study . Intensive Care Medicine vol. 46 , ( 5 ) 943 - 953 .

McLean KA, Ahmed WUR, Akhbari M, Claireaux HA, English C, Frost J, Henshall DE, Khan M et al. ( 2020 ) . Perioperative intravenous contrast administration and the incidence of acute kidney injury after major gastrointestinal surgery: prospective, multicentre cohort study . British Journal of Surgery

Vaara ST, Ostermann M, Selander T, Bitker L, Schneider A, Poli E, Hoste E, Joannidis M et al. ( 2020 ) . Protocol and statistical analysis plan for the REstricted fluid therapy VERsus Standard trEatment in Acute Kidney Injury - REVERSE-AKI randomized controlled pilot trial . Acta Anaesthesiol Scand

Fowler A, Prowle J, Pearse R, Cromwell D ( 2020 ) . Chronic disease within the NHS surgical population: An epidemiological study statistical analysis plan .

Wan Y, McGuckin D, Fowler A, Prowle J, Pearse R, Moonesinghe R ( 2020 ) . Socioeconomic deprivation and surgical outcomes: ISOS and VISION-UK sub-study (Statistical Analysis Plan) .

Haines R, Fowler AJ, Wan Y, Heyland DK, Day A, Puthucheary Z, Prowle J ( 2020 ) . Urea-to-creatinine ratio trajectories in multi-organ failure: a reanalysis of the REDOXS trial statistical analysis plan .

Nepogodiev D ( 2019 ) . Challenges of one-year longitudinal follow-up of a prospective, observational cohort study using an anonymised database: recommendations for trainee research collaboratives . BMC Medical Research Methodology vol. 19 , ( 1 )

Joannidis M, Forni LG, Klein SJ, Honore PM, Kashani K, Ostermann M, Prowle J, Bagshaw SM et al. ( 2019 ) . Lung-kidney interactions in critically ill patients: consensus report of the Acute Disease Quality Initiative (ADQI) 21 Workgroup . Intensive Care Medicine

Ostermann M, Schneider A, Rimmele T, Bobek I, van Dam M, Darmon M, Forni L, Joannes-Boyau O et al. ( 2019 ) . Report of the first AKI Round Table meeting: an initiative of the ESICM AKI Section . Intensive Care Medicine Experimental vol. 7 , ( 1 )

Harrois A, Anstey JR, Taccone FS, Udy AA, Citerio G, Duranteau J, Ichai C, Badenes R et al. ( 2019 ) . Correction to: Serum sodium and intracranial pressure changes after desmopressin therapy in severe traumatic brain injury patients: a multi-centre cohort study . vol. 9 , is. 1 , Springer Nature

Haines RW, Zolfaghari P, Wan Y, Pearse RM, Puthucheary Z, Prowle JR ( 2019 ) . Elevated urea-to-creatinine ratio provides a biochemical signature of muscle catabolism and persistent critical illness after major trauma . Intensive Care Med vol. 45 , ( 12 ) 1718 - 1731 .

Legrand M, Prowle JR, Forni LG ( 2019 ) . The artificial kidney induces AKI? Not if we apply “kidney-protective” renal replacement therapy . Intensive Care Medicine

Girling BJ, Channon SW, Haines RW, Prowle JR ( 2019 ) . Acute kidney injury and adverse outcomes of critical illness: correlation or causation? . Clinical Kidney Journal vol. 13 , ( 2 ) 133 - 141 .

Macdonald N, Pearse RM, Murray PT, Inzitari R, Doran P, Prowle JR ( 2019 ) . The role of goal-directed therapy in the prevention of acute kidney injury after major gastrointestinal surgery: Substudy of the OPTIMISE trial . European Journal of Anaesthesiology vol. 36 , ( 12 ) 924 - 932 .

Haines RW, Kirwan CJ, Prowle JR ( 2019 ) . Managing Chloride and Bicarbonate in the Prevention and Treatment of Acute Kidney Injury . Seminars in Nephrology vol. 39 , ( 5 ) 473 - 483 .

Perkins ZB, Haines RW, Prowle JR ( 2019 ) . Trauma-associated acute kidney injury . Curr Opin Crit Care

Harrois A, Anstey JR, Taccone FS, Udy AA, Citerio G, Duranteau J, Ichai C, Badenes R et al. ( 2019 ) . Serum sodium and intracranial pressure changes after desmopressin therapy in severe traumatic brain injury patients: a multi-centre cohort study . Annals of Intensive Care vol. 9 , ( 1 )

Prowle JR ( 2019 ) . Introduction: Acute Kidney Injury Management in 2019: Somethings Old Somethings New . Seminars in Nephrology vol. 39 , ( 5 ) 419 - 420 .

Anstey J, Taccone F, Udy A, Citerio G, Duranteau J, Ichai C, Badenes R, Prowle J et al. ( 2019 ) . Early osmotherapy in severe traumatic brain injury: an international multicentre study . J Neurotrauma

Fowler AJ, ABBOTT T, PROWLE J, PEARSE R ( 2019 ) . Age of patients undergoing surgery . British Journal of Surgery

Haller G, Bampoe S, Cook T, Fleisher LA, Grocott MPW, Neuman M, Story D, Myles PS et al. ( 2019 ) . Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators . British Journal of Anaesthesia

Haines RW, Harrois A, Prowle JR, Søvik S, Beitland S ( 2019 ) . Deserved attention for acute kidney injury after major trauma . Intensive Care Medicine vol. 45 , ( 6 ) 907 - 908 .

Haines RW, Prowle JR ( 2019 ) . Diagnostic Implications of Creatinine and Urea Metabolism in Critical Illness . Annual Update in Intensive Care and Emergency Medicine 2019 , Springer Nature

Risk Investigators ( 2019 ) . Risk prediction for acute kidney injury in acute medical admissions in the UK . QJM vol. 112 , ( 3 ) 197 - 205 .

Haines RW, Prowle JR ( 2019 ) . Renal Protection in Critically Ill Patients . Kidney Protection , Oxford University Press (OUP)

Ferrada P, Strumwasser A, Zarbock A, Mackey C, Wilkinson J, Handisides D, Prowle J ( 2019 ) . 1623: EFFECT OF ANGIOTENSIN II ON VASOPRESSOR DOSE AND SAFETY IN PATIENTS WITH SEVERE VASODILATORY SHOCK . Critical Care Medicine vol. 47 , ( 1 ) 786 - 786 .

Prowle JR, Kirwan CJ, Honoré PM, Jacobs R, Spapen HD ( 2019 ) . Acute Kidney Injury in Burns and Trauma . Critical Care Nephrology: Third Edition ,

De Rosa S, Prowle JR, Samoni S, Villa G, Ronco C ( 2019 ) . Acute Kidney Injury in Patients With Chronic Kidney Disease . Critical Care Nephrology: Third Edition ,

De Rosa S, Prowle JR, Samoni S, Villa G, Ronco C ( 2019 ) . Chapter 14 Acute Kidney Injury in Patients With Chronic Kidney Disease . Critical Care Nephrology , Elsevier

Prowle JR, Forni LG ( 2019 ) . Chapter 25 Functional Biomarkers . Critical Care Nephrology , Elsevier

Prowle JR, Kirwan CJ, Honoré PM, Jacobs R, Spapen HD ( 2019 ) . Chapter 38 Acute Kidney Injury in Burns and Trauma . Critical Care Nephrology , Elsevier

Prowle JR, Forni LG ( 2019 ) . Functional Biomarkers . Critical Care Nephrology: Third Edition ,

Prowle J, Du B, Wang C, Gallagher M ( 2019 ) . Pragmatic Studies for Acute Kidney Injury in China: Renal Replacement Therapy for Acute Kidney Injury and Sepsis Consensus Report of Acute Disease Quality Initiative XIX . Journal of Translational Critical Care Medicine vol. 1 , ( 2 ) 48 - 48 .

Barnes J, Hunter J, Harris S, Shankar-Hari M, Diouf E, Jammer I, Kalkman C, Klein AA et al. ( 2019 ) . Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis . British Journal of Anaesthesia

Bell S, Prowle J ( 2018 ) . Postoperative AKI-Prevention Is Better than Cure? . J Am Soc Nephrol

Haines RW, Kirwan CJ, Prowle JR ( 2018 ) . Continuous renal replacement therapy: individualization of the prescription . Curr Opin Crit Care

Chaudery H, MacDonald N, Ahmad T, Chandra S, Tantri A, Sivasakthi V, Mansor M, Matos R et al. ( 2018 ) . Acute Kidney Injury and Risk of Death After Elective Surgery: Prospective Analysis of Data From an International Cohort Study . Anesth Analg

Haines RW, Fowler AJ, Kirwan CJ, Prowle JR ( 2018 ) . The Incidence and Associations of Acute Kidney Injury in Trauma Patients Admitted to Critical Care: A Systematic Review and Meta-analysis . J Trauma Acute Care Surg

Drake TM, Cheung LK, Gaba F, Glasbey J, Griffiths N, Helliwell RJ, Huq T, Khaw R et al. ( 2018 ) . Association between peri-operative angiotensin-converting enzyme inhibitors and angiotensin-2 receptor blockers and acute kidney injury in major elective non-cardiac surgery: a multicentre, prospective cohort study . Anaesthesia vol. 73 , ( 10 ) 1214 - 1222 .

McIlroy DR, Bellomo R, Billings FT, Karkouti K, Prowle JR, Shaw AD, Myles PS ( 2018 ) . Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: renal endpoints . British Journal of Anaesthesia vol. 121 , ( 5 ) 1013 - 1024 .

Prowle JR ( 2018 ) . Non-dialytic Management of Acute Kidney Injury . Core Concepts in Acute Kidney Injury , Springer Nature

Schetz M, Prowle J ( 2018 ) . Focus on acute kidney injury 2017 . Intensive Care Medicine vol. 44 , ( 11 ) 1992 - 1994 .

Atan R, Peck L, Eastwood G, Licari E, Goehl H, PROWLE JR, Storr M, Bellomo R ( 2018 ) . A double-blind randomized controlled trial of high cut-off vs. standard hemofiltration in critically ill patients with acute kidney injury . Critical Care Medicine

STARSurg Collaborative, Writing Committee, Data analysis, Steering committee, Advisory group, Regional leads, Collaborators and validators ( 2018 ) . Prognostic model to predict postoperative acute kidney injury in patients undergoing major gastrointestinal surgery based on a national prospective observational cohort study . BJS Open vol. 2 , ( 6 ) 400 - 410 .

Prowle JR ( 2018 ) . Challenges of performing renal replacement therapy in the intensive care unit - The intensivist perspective . Clinical Nephrology vol. 90 , ( 1 ) 6 - 10 .

JONES TF, BEKELE S, O'DWYER M, PROWLE JR ( 2018 ) . MicroRNAs in acute kidney injury . Nephron

Arulkumaran N, Prowle JR ( 2018 ) . Natriuretic Peptides: A Role in Early Septic Acute Kidney Injury? . Anesthesiology

Tumlin JA, Murugan R, Deane AM, Ostermann M, Busse LW, Ham KR, Kashani K, Szerlip HM et al. ( 2018 ) . Outcomes in Patients with Vasodilatory Shock and Renal Replacement Therapy Treated with Intravenous Angiotensin II . Critical care medicine vol. 46 , ( 6 ) 949 - 957 .

Prowle JR ( 2018 ) . Renal Blood Flow Measurement in Early Clinical Sepsis-Can You Catch a Shadow? . Critical care medicine vol. 46 , ( 6 ) 1028 - 1030 .

Haines RW, Lin S-P, Hewson R, Kirwan CJ, Torrance HD, O'Dwyer MJ, West A, Brohi K et al. ( 2018 ) . Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model . Scientific reports vol. 8 , ( 1 )

Kellum JA, Prowle JR ( 2018 ) . Paradigms of acute kidney injury in the intensive care setting . Nat Rev Nephrol vol. 14 , 217 - 230 .

KIRWAN CJ, Jackson L, Prowle JR ( 2017 ) . A Continuous Renal Replacement Therapy Protocol on the Updated Nikkiso Aquarius Platform Using Regional Citrate as First-Line Anticoagulation Significantly Improves Filter Life Span but the Position of the Vascular Access is Key . Blood Purification129 - 130 .

Peng Z, Yu K, Ostermann M, Xi X, Hsu R, Vincent J-L, Prowle JR, Du B et al. ( 2017 ) . Pragmatic studies for acute kidney injury: Consensus report of the Acute Disease Quality Initiative (ADQI) 19 Workgroup . Journal of Critical Care vol. 44 , 337 - 344 .

Prowle JR ( 2017 ) . Sepsis-Associated AKI . Clinical journal of the American Society of Nephrology : CJASN vol. 13 , ( 2 ) 339 - 342 .

Ravn B, Prowle JR, Mårtensson J, Martling C-R, Bell M ( 2017 ) . Superiority of Serum Cystatin C Over Creatinine in Prediction of Long-Term Prognosis at Discharge From ICU . Critical care medicine vol. 45 , ( 9 ) e932 - e940 .

Szakmany T, Ditai J, Kirov M, Protsenko D, Osinaike B, Venara A, Demartines N, Hubner M et al. ( 2017 ) . In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study . EJSO - European Journal of Surgical Oncology

Khanna A, English SW, Wang XS, Ham K, Tumlin J, Szerlip H, Busse LW, Altaweel L et al. ( 2017 ) . Angiotensin II for the Treatment of Vasodilatory Shock . N Engl J Med vol. 377 , ( 5 ) 419 - 430 .

Chaudery H, MacDonald N, Pearse RM, Prowle JR ( 2017 ) . Global Incidence and Associations of Acute Kidney Injury in the International Surgical Outcomes Study (ISOS) . vol. 119 , is. 2 , pp. E28 - E28 .

Adwaney A, Randall DW, Blunden MJ, Prowle JR, Kirwan CJ ( 2017 ) . Perioperative Plasma-Lyte use reduces the incidence of renal replacement therapy and hyperkalaemia following renal transplantation when compared with 0.9% saline: a retrospective cohort study . Clinical Kidney Journal

O’Connor ME, Jones SL, Glassford NJ, Bellomo R, PROWLE JR ( 2017 ) . Defining fluid removal in the intensive care unit: A national and international survey of critical care practice . Journal of the Intensive Care Society

Perner A, Prowle J, Joannidis M, Young P, Hjortrup PB, Pettilä V ( 2017 ) . Fluid management in acute kidney injury . Intensive Care Med vol. 43 , ( 6 ) 807 - 815 .

Forni LG, Darmon M, Ostermann M, Oudemans-van Straaten HM, Pettilä V, Prowle JR, Schetz M, Joannidis M ( 2017 ) . Renal recovery after acute kidney injury . Intensive Care Medicine vol. 43 , ( 6 ) 855 - 866 .

Prowle JR, Rosner MH ( 2017 ) . Have biomarkers failed in acute kidney injury? We are not sure . Intensive care medicine vol. 43 , ( 6 ) 890 - 892 .

O'Connor ME, Hewson RW, Kirwan CJ, Ackland GL, Pearse RM, Prowle JR ( 2017 ) . Acute kidney injury and mortality 1 year after major non-cardiac surgery . British Journal of Surgery

Prowle JR, Schetz M ( 2017 ) . Validating benefit of biomarker-directed therapy for acute kidney injury: can you have your cake and eat it? . Intensive Care Medicine vol. 43 , ( 4 ) 578 - 580 .

Pickers P, Ostermann M, Joannidis M, Zarbock A, Hoste E, Bellomo R, Darmon M, Prowle JR et al. ( 2017 ) . The intensive care medicine agenda on acute kidney injury . Intensive Care Medicine

Patel A, Prowle JR, Ackland GL, Investigators P-OS ( 2017 ) . Postoperative goal-directed therapy and development of acute kidney injury following major elective noncardiac surgery: post-hoc analysis of POM-O randomized controlled trial . Clinical Kidney Journal vol. 10 , ( 3 ) 348 - 356 .

BEILSTEIN C, PROWLE JR, KIRWAN CJ ( 2016 ) . Automated fluid management for treatment of Rhabdomyolysis . International Journal of Nephrology Article 2932593 ,

Kirwan CJ, Hutchinson R, Ghabina S, Beane A, Ramsay S, Thompson E, Prowle JR ( 2016 ) . Implementation of a simplified regional citrate anticoagulation protocol for post-dilution continuous hemofiltration using a bicarbonate buffered, calcium containing replacement solution . Blood Purification vol. 42 , 349 - 355 .

Velasquez T, Mackey G, Lusk J, Kyle UG, Fontenot T, Marshall P, Shekerdemian LS, Coss-Bu JA et al. ( 2016 ) . ESICM LIVES 2016: part three : Milan, Italy. 1-5 October 2016 . Intensive Care Med Exp . Conference: ESICM LIVES 2016 ( Germany ) vol. 4 , 28 - 28 .

Sivakumar S, Taccone FS, Desai KA, Lazaridis C, Skarzynski M, Sekhon M, Henderson W, Griesdale D et al. ( 2016 ) . ESICM LIVES 2016: part two : Milan, Italy. 1-5 October 2016 . Intensive Care Med Exp . Conference: ESICM Lives 2016 ( Germany ) vol. 4 , 30 - 30 .

Gordon AC, Mason AJ, Thirunavukkarasu N, Perkins GD, Cecconi M, Cepkova M, Pogson DG, Aya HD et al. ( 2016 ) . Effect of Early Vasopressin vs Norepinephrine on Kidney Failure in Patients With Septic Shock: The VANISH Randomized Clinical Trial . JAMA vol. 316 , ( 5 ) 509 - 518 .

PROWLE JR ( 2016 ) . Pathophysiology of oliguria and acute kidney injury . Oxford Textbook of Critical Care , Oxford University Press

PROWLE JR ( 2016 ) . Renal injury biomarkers in the critically ill . Oxford Textbook of Critical Care , Oxford University Press

Prowle JR, Kam EPY, Ahmad T, Smith NCE, Protopapa K, Pearse RM ( 2016 ) . Preoperative renal dysfunction and mortality after non-cardiac surgery . British Journal of Surgery vol. 103 , ( 10 ) 1316 - 1325 .

Gross JL, Prowle JR ( 2016 ) . Perioperative acute kidney injury . Update in Anaesthesia vol. 31 , 24 - 30 .

Myles PS, Grocott MPW, Boney O, Moonesinghe SR, COMPAC-StEP Group ( 2016 ) . Standardizing end points in perioperative trials: towards a core and extended outcome set . Br J Anaesth vol. 116 , ( 5 ) 586 - 589 .

Nelson A, Otto J, Whittle J, Stephens RCM, Martin DS, Prowle JR, Ackland GL ( 2016 ) . Subclinical cardiopulmonary dysfunction in stage 3 chronic kidney disease . Open Heart vol. 3 , ( 1 )

Collaborative S, Bath* M, Glasbey* J, Claireaux H, Drake T, Gundogan B, Khatri C, Kong N et al. ( 2016 ) . Outcomes After Kidney injury in Surgery (OAKS): protocol for a multicentre, observational cohort study of acute kidney injury following major gastrointestinal and liver surgery . BMJ Open vol. 6 , ( 1 )

Ronco C, Ricci Z, De Backer D, Kellum JA, Taccone FS, Joannidis M, Pickkers P, Cantaluppi V et al. ( 2015 ) . Renal replacement therapy in acute kidney injury: controversy and consensus . Critical Care vol. 19 , ( 1 )

O’Connor ME, Kirwan CJ, Pearse RM, Prowle JR ( 2015 ) . Incidence and associations of acute kidney injury after major abdominal surgery . Intensive Care Medicine vol. 42 , ( 4 ) 521 - 530 .

PROWLE JR, Bellomo R ( 2015 ) . Acute kidney injury in severe sepsis . Oxford Textbook of Clinical Nephrology , Editors: Turner, N, Lameire, N, Goldsmith, DJ, Winearls, CG et al. , Edition. 4th , Oxford University Press

Prowle JR, Davenport A ( 2015 ) . Does early-start renal replacement therapy improve outcomes for patients with acute kidney injury? . Kidney International vol. 88 , ( 4 ) 670 - 673 .

Gross JL, Prowle JR ( 2015 ) . Perioperative acute kidney injury . BJA Education vol. 15 , ( 4 ) 213 - 218 .

O’Connor ME, Prowle JR ( 2015 ) . Fluid Overload . Critical Care Clinics vol. 31 , ( 4 ) 803 - 821 .

Prowle JR, Kolic I, Kirwan C ( 2015 ) . SP243DIVERGENT CHANGES IN SERUM CREATININE AND UREA IN SURVIVORS OF PROLONGED CRITICAL ILLNESS . Nephrology Dialysis Transplantation . vol. 30 , iii458 - iii459 .

Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O'Dwyer MJ ( 2015 ) . Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients . Annals of Surgery vol. 261 , ( 4 ) 751 - 759 .

Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, OʼDwyer MJ ( 2015 ) . Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients . Ann Surg vol. 261 , ( 4 ) 751 - 759 .

O'Connor M, Galtrey E, Kirwan C, Prowle J ( 2015 ) . Bioimpedance as a measure of fluid overload in patients recently admitted to intensive care . Critical Care vol. 19 , ( Suppl 1 )

Kirwan CJ, Blunden MJ, Dobbie H, James A, Nedungadi A, Prowle JR ( 2015 ) . Critically Ill Patients Requiring Acute Renal Replacement Therapy Are at an Increased Risk of Long-Term Renal Dysfunction, but Rarely Receive Specialist Nephrology Follow-Up . Nephron vol. 129 , ( 3 ) 164 - 170 .

Prowle JR ( 2015 ) . Measurement of AKI biomarkers in the ICU: still striving for appropriate clinical indications . Intensive Care Medicine vol. 41 , ( 3 ) 541 - 543 .

Ackland GL, Prowle JR ( 2015 ) . Presepsin: solving a soluble (CD14) problem in sepsis? . Intensive Care Medicine vol. 41 , ( 2 ) 351 - 353 .

Prowle JR, Calzavacca P, Licari E, Ligabo EV, Echeverri JE, Bagshaw SM, Haase-Fielitz A, Haase M et al. ( 2015 ) . Combination of biomarkers for diagnosis of acute kidney injury after cardiopulmonary bypass . Renal Failure vol. 37 , ( 3 ) 408 - 416 .

Torrance HD, Vivian ME, Brohi K, Prowle JR, Pearse RM, Owen HC, Hinds CJ, O'Dwyer MJ ( 2015 ) . Changes in gene expression following trauma are related to the age of transfused packed red blood cells . J Trauma Acute Care Surg vol. 78 , ( 3 ) 535 - 542 .

Forni LG, Prowle J ( 2015 ) . Classical Biochemical Work Up of the Patient with Suspected AKI . Acute Nephrology for the Critical Care Physician , Springer Nature

de Pont A-CJM, Prowle JR, Legrand M, Groeneveld ABJ ( 2015 ) . Etiology and Pathophysiology of Acute Kidney Injury . Acute Nephrology for the Critical Care Physician , Springer Nature

Prowle JR, Kirwan CJ, Bellomo R ( 2015 ) . Renal Outcomes After Acute Kidney Injury . Acute Nephrology for the Critical Care Physician , Springer Nature

Prowle JR, Bellomo R ( 2015 ) . Sepsis-Associated Acute Kidney Injury: Macrohemodynamic and Microhemodynamic Alterations in the Renal Circulation . Seminars in Nephrology vol. 35 , ( 1 ) 64 - 74 .

Prowle JR, Leitch A, Kirwan CJ, Forni LG ( 2014 ) . Positive fluid balance and AKI diagnosis: assessing the extent and duration of ‘creatinine dilution’ . Intensive Care Medicine vol. 41 , ( 1 ) 160 - 161 .

Prowle JR ( 2014 ) . Does Augmented Creatinine Clearance Accurately Reflect Glomerular Hyperfiltration in Critical Illness? . Critical Care Medicine vol. 42 , ( 10 ) e674 - e675 .

Rosner MH, Ostermann M, Murugan R, Prowle JR, Ronco C, Kellum JA, Mythen MG, Shaw AD et al. ( 2014 ) . Indications and management of mechanical fluid removal in critical illness . British Journal of Anaesthesia vol. 113 , ( 5 ) 764 - 771 .

Prowle JR, Kirwan CJ ( 2014 ) . Acute Kidney Injury After Cardiac Surgery . Critical Care Medicine vol. 42 , ( 9 ) 2142 - 2143 .

Torrance HD, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O’Dwyer MJ ( 2014 ) . Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients . Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine . vol. 22 ,

Fragkou P, Prowle J, Ackland G, Hinds C, Pearse R, O'Dwyer MJ ( 2014 ) . Perioperative blood transfusion is associated with a characteristic immune response, excess infectious complications and death in patients undergoing scheduled major gastrointestinal surgery . European Journal of Anaesthesiology . vol. 31 ,

Prowle JR ( 2014 ) . Haemodialysis before emergency surgery in a patient treated with dabigatran . British Journal of Anaesthesia vol. 112 , ( 5 ) 941 - 942 .

Prowle JR, Kolic I, Purdell-Lewis J, Taylor R, Pearse RM, Kirwan CJ ( 2014 ) . Serum Creatinine Changes Associated with Critical Illness and Detection of Persistent Renal Dysfunction after AKI . Clinical Journal of the American Society of Nephrology vol. 9 , ( 6 ) 1015 - 1023 .

Prowle J, Kolic I, Purdell-Lewis J, Kirwan C ( 2014 ) . Acute kidney injury of all severity is associated with extended hospitalization after critical illness . Critical Care vol. 18 , ( Suppl 1 )

Rajendram R, Prowle J ( 2014 ) . Perioperative fluid balance and postoperative changes in serum creatinine in patients admitted to critical care after elective major surgery . Critical Care vol. 18 , ( Suppl 1 )

Rajendram R, Prowle JR ( 2014 ) . Venous congestion: are we adding insult to kidney injury in sepsis? . Critical Care vol. 18 , ( 1 )

Torrance HDT, Brohi K, Pearse RM, Mein CA, Wozniak E, Prowle JR, Hinds CJ, O’Dwyer MJ ( 2014 ) . Association between gene expression biomarkers of immunosuppression and blood transfusion in severely injured polytrauma patients . Scandinavian journal of trauma, resuscitation and emergency medicine vol. 22 , ( Suppl 1 ) O7 - O7 .

Poply K, Schwartz S, Lucena-Amaro S, Ramsey S, Robinson M, Kirwan CJ, Prowle JR ( 2014 ) . FILETER LIFE AND ANTICOAGULATION ISE IN A MIXED MEDICAL/SURGICAL/TRAUIVLA ICU: A BASELINE ASSESSMENT . INTENSIVE CARE MEDICINE . vol. 40 , S55 - S55 .

Amin N, Prowle JR, Kirwan CJ ( 2014 ) . FLUID ADMINISTRATION AND ITS EFFECT ON ELECTROLYTES IN CRITICALLY ILL TRAUMA PATIENTS . INTENSIVE CARE MEDICINE . vol. 40 , S282 - S283 .

Fragkou PC, Torrance HD, Pearse RM, Ackland GL, Prowle JR, Owen HC, Hinds CJ, O'Dwyer MJ ( 2014 ) . Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study . Crit Care vol. 18 , ( 5 ) 014 - 0541 .

Atan R, Prowle J, Peck L, Eastwood G, Bellomo R ( 2013 ) . Randomized controlled study of high cut-off point hemofiltration vs. standard hemofiltration in acute renal failure . Journal of Critical Care vol. 28 , ( 6 )

Prowle JR, Kirwan CJ, Bellomo R ( 2013 ) . Fluid management for the prevention and attenuation of acute kidney injury . Nature Reviews Nephrology vol. 10 , ( 1 ) 37 - 47 .

Prowle JR, Bellomo R ( 2013 ) . Fluid administration and the kidney . Current Opinion in Critical Care vol. 19 , ( 4 ) 308 - 314 .

Haase-Fielitz A, Plaß M, Kuppe H, Hetzer R, Ostland V, Westphal S, Hoffmann J, Prowle J et al. ( 2013 ) . Low preoperative hepcidin concentration as a risk factor for mortality after cardiac surgery: a pilot study . J Thorac Cardiovasc Surg vol. 145 , ( 5 ) 1380 - 1386 .

Prowle JR, Pearse RM ( 2013 ) . Is it the end of the road for synthetic starches in critical illness? . The BMJ vol. 346 , ( mar20 1 )

Kolic I, Purdell-Lewis J, Kirwan C, Prowle J ( 2013 ) . Estimated glomerular filtration rate based on hospital discharge creatinine may significantly overestimate renal function and underestimate chronic kidney disease in survivors of critical illness . Critical Care vol. 17 , ( Suppl 2 )

Kirwan C, Taylor R, Prowle J ( 2013 ) . Survivors of acute kidney injury requiring renal replacement therapy rarely receive follow-up: identification of an unmet need . Critical Care vol. 17 , ( Suppl 2 )

Prowle JR ( 2013 ) . Creatinine and AKI—through a glass, darkly . Nature Reviews Nephrology vol. 9 , ( 4 ) 193 - 195 .

investigators TMETE-O-LC ( 2013 ) . The timing of Rapid-Response Team activations: a multicentre international study . Critical Care and Resuscitation vol. 15 , ( 1 ) 15 - 20 .

Prowle JR ( 2013 ) . Acute kidney injury: an intensivist’s perspective . Pediatric Nephrology vol. 29 , ( 1 ) 13 - 21 .

Prowle JR, Kolic I, Purdell-Lewis J, Taylor R, Kirwan CJ ( 2013 ) . ACUTE KIDNEY INJURY IN THE ICU IS INDEPENDENTLY ASSOCIATED WITH ANAEMIA AT HOSPITAL DISCHARGE . INTENSIVE CARE MEDICINE . vol. 39 , S260 - S261 .

Kirwan CJ, Prowle JR ( 2013 ) . Acute Kidney Injury Is a Chronic Disease that Requires Long-Term Follow-up . Annual Update in Intensive Care and Emergency Medicine 2013 , Springer Nature

Prowle JR, Leitch A, Kirwan CJ, Forni LG ( 2013 ) . KINETIC MODELLING OF PLASMA CREATININE CHANGES AFTER AKI: EFFECT OF VOLUME EXPANSION AND CHANGE IN GENERATION RATE . INTENSIVE CARE MEDICINE . vol. 39 , S389 - S389 .

Chakkalakal N, Taylor R, Marshall G, Healy M, Kirwan CJ, Prowle JR ( 2013 ) . RHABDOMYOLYSIS AND ACUTE KIDNEY INJURY: INCIDENCE, TREATMENTS AND OUTCOMES IN THE ICU . INTENSIVE CARE MEDICINE . vol. 39 , S263 - S263 .

Prowle J, Bagshaw SM, Bellomo R ( 2012 ) . Renal blood flow, fractional excretion of sodium and acute kidney injury: time for a new paradigm? . Curr Opin Crit Care vol. 18 , ( 6 ) 585 - 592 .

Prowle JR, Bellomo R ( 2012 ) . Assessment of renal perfusion . Critical Care Medicine vol. 40 , ( 10 ) 2921 - 2922 .

Prowle JR, Chua H-R, Bagshaw SM, Bellomo R ( 2012 ) . Clinical review: Volume of fluid resuscitation and the incidence of acute kidney injury - a systematic review . Critical Care vol. 16 , ( 4 )

Prowle JR ( 2012 ) . Fluid resuscitation in septic shock: too much, too little or just right? . Critical Care vol. 16 , ( 3 )

Eastwood GM, Peck L, Young H, Prowle J, Vasudevan V, Jones D, Bellomo R ( 2012 ) . Intravenous fluid administration and monitoring for adult ward patients in a teaching hospital . Nurs Health Sci vol. 14 , ( 2 ) 265 - 271 .

Prowle JR, Molan MP, Hornsey E, Bellomo R ( 2012 ) . Measurement of renal blood flow by phase-contrast magnetic resonance imaging during septic acute kidney injury . Critical Care Medicine vol. 40 , ( 6 ) 1768 - 1776 .

PROWLE JR, CALZAVACCA P, LICARI E, LIGABO EV, ECHEVERRI JE, HAASE M, HAASE‐FIELITZ A, BAGSHAW SM et al. ( 2012 ) . Pilot double‐blind, randomized controlled trial of short‐term atorvastatin for prevention of acute kidney injury after cardiac surgery . Nephrology vol. 17 , ( 3 ) 215 - 224 .

Prowle JR, Bellomo R ( 2012 ) . ASSESSING MULTIPLE BIOMARKERS FOR DIAGNOSIS OF ACUTE KIDNEY INJURY AFTER GARDIOPULMONARY BYPASS . INTENSIVE CARE MEDICINE vol. 38 , S121 - S121 .

Prowle JR, Bellomo R ( 2012 ) . Hemofiltration in the ICU . Encyclopedia of Intensive Care Medicine , Springer Nature

Kim IB, Prowle J, Baldwin I, Bellomo R ( 2012 ) . Incidence, risk factors and outcome associations of intra-abdominal hypertension in critically ill patients . Anaesth Intensive Care vol. 40 , ( 1 ) 79 - 89 .

Prowle JR, Bellomo R ( 2012 ) . Renal Replacement . Encyclopedia of Intensive Care Medicine , Springer Nature

Prowle JR, Bellomo R ( 2012 ) . Urine Output and the Diagnosis of Acute Kidney Injury . Annual Update in Intensive Care and Emergency Medicine 2012 , Springer Nature

Eastwood GM, Peck L, Young H, Prowle J, Jones D, Bellomo R ( 2011 ) . Oxygen administration and monitoring for ward adult patients in a teaching hospital . Intern Med J vol. 41 , ( 11 ) 784 - 788 .

Haase-Fielitz A, Mertens PR, Plaß M, Kuppe H, Hetzer R, Westerman M, Ostland V, Prowle JR et al. ( 2011 ) . Urine hepcidin has additive value in ruling out cardiopulmonary bypass-associated acute kidney injury: an observational cohort study . Critical Care vol. 15 , ( 4 )

Prowle JR, Ostland V, Calzavacca P, Licari E, Ligabo EV, Echeverri JE, Bagshaw SM, Haase-Fielitz A et al. ( 2011 ) . Greater increase in urinary hepcidin predicts protection from acute kidney injury after cardiopulmonary bypass . Nephrology Dialysis Transplantation vol. 27 , ( 2 ) 595 - 602 .

Prowle JR, Liu Y-L, Licari E, Bagshaw SM, Egi M, Haase M, Haase-Fielitz A, Kellum JA et al. ( 2011 ) . Oliguria as predictive biomarker of acute kidney injury in critically ill patients . Critical Care vol. 15 , ( 4 )

WESTERMAN MARK E, BELLOMO RINALDO, PROWLE JOHN, BROWNSTEIN MICHAEL ( 2011 ) . MARKERS FOR ACUTE KIDNEY INJURY .

Prowle JR, Echeverri JE, Ligabo EV, Sherry N, Taori GC, Crozier TM, Hart GK, Korman TM et al. ( 2011 ) . Acquired bloodstream infection in the intensive care unit: incidence and attributable mortality . Critical Care vol. 15 , ( 2 )

Prowle JR, Schneider A, Bellomo R ( 2011 ) . Clinical review: Optimal dose of continuous renal replacement therapy in acute kidney injury . Critical Care vol. 15 , ( 2 )

Prowle JR, Heenen S, Singer M ( 2011 ) . Infection in the critically ill—questions we should be asking . Journal of Antimicrobial Chemotherapy vol. 66 , ( suppl_2 ) ii3 - ii10 .

Prowle JR, Bellomo R ( 2011 ) . Distinction between induction and maintenance dosing in continuous renal replacement therapy response . CRITICAL CARE vol. 15 , ( 2 )

Haase-Fielitz A, Mertens PR, Plass M, Kuppe H, Hetzer R, Westerman M, Ostland V, Prowle JR et al. ( 2011 ) . URINE HEPCIDIN IS AN EARLY PREDICTOR OF PROTECTION FROM CARDIOPULMONARY BYPASS-ASSOCIATED ACUTE KIDNEY INJURY - AN OBSERVATIONAL COHORT STUDY . INTENSIVE CARE MEDICINE . vol. 37 , S208 - S208 .

Prowle JR ( 2010 ) . A complicated hyperglycaemic emergency . Clinical Medicine vol. 10 , ( 6 ) 641 - 642 .

Prowle JR, Westerman M, Bellomo R ( 2010 ) . Urinary hepcidin: an inverse biomarker of acute kidney injury after cardiopulmonary bypass? . Current Opinion in Critical Care vol. 16 , ( 6 ) 540 - 544 .

Bellomo R, Prowle JR, Echeverri JE ( 2010 ) . Diuretic therapy in fluid-overloaded and heart failure patients . vol. 164 ,

Prowle JR, Bellomo R ( 2010 ) . Fluid administration and the kidney . Current Opinion in Critical Care vol. 16 , ( 4 ) 332 - 336 .

Prowle JR, Bellomo R ( 2010 ) . Continuous renal replacement therapy: recent advances and future research . Nature Reviews Nephrology vol. 6 , ( 9 ) 521 - 529 .

Prowle JR, Molan MP, Hornsey E, Bellomo R ( 2010 ) . Ciné Phase-Contrast Magnetic Resonance Imaging for the Measurement of Renal Blood Flow . Contributions to Nephrology vol. 165 , 329 - 336 .

Bellomo R, Prowle JR, Echeverri JE ( 2010 ) . Diuretic Therapy in Fluid-Overloaded and Heart Failure Patients . Contributions to Nephrology vol. 164 , 153 - 163 .

Bellomo R, Prowle JR, Echeverri JE, Ligabo V, Ronco C ( 2010 ) . Fluid Management in Septic Acute Kidney Injury and Cardiorenal Syndromes . Contributions to Nephrology vol. 165 , 206 - 218 .

Prowle JR, Ishikawa K, May CN, Bellomo R ( 2010 ) . Renal plasma flow and glomerular filtration rate duringacute kidney injury in man . Renal Failure vol. 32 , ( 3 ) 349 - 355 .

Prowle JR, Echeverri JE, Ligabo EV, Taori GC, Crozier TM, Hart GK, Tony KM, Mayall B et al. ( 2010 ) . ACQUIRED BLOODSTREAM INFECTION IN THE ICU: MICROBIOLOGICAL DIAGNOSIS AND MORTALITY . INTENSIVE CARE MEDICINE . vol. 36 , S208 - S208 .

Prowle JR, Molan MP, Hornsey E, Bellomo R ( 2010 ) . CINE PHASE-CONTRAST MAGNETIC RESONANCE IMAGING FOR THE MEASUREMENT OF ORGAN BLOOD FLOW IN CRITICAL ILLNESS . INTENSIVE CARE MEDICINE . vol. 36 , S116 - S116 .

Bagshaw SM, Prowle J, Bellomo R ( 2010 ) . Chapter 66 Acute kidney injury . The ESC Textbook of Intensive and Acute Cardiac Care , Oxford University Press (OUP)

Prowle JR, Licari E, Calzavacca P, Ligabo EV, Echeverri JE, Hasse M, Bagshaw SM, Bellomo R ( 2010 ) . PERI-OPERATIVE STATIN THERAPY DOES NOT ALTER THE INCIDENCE OF ACUTE KIDNEY INJURY AFTER CARDIOPULMONARY BYPASS: CREAT, THE CARDIOPULMONARY BYPASS, RENAL INJURY AND ATORVASTATIN TRIAL. CLINICALTRIALS.GOV NCT00910221 . INTENSIVE CARE MEDICINE . vol. 36 , S88 - S88 .

Bellomo R, Palevsky PM, Bagshaw SM, Gibney N, McAlister FA, Honore PM, Joannes-Boyau O, Prowle J et al. ( 2010 ) . Recent trials in critical care nephrology . Contrib Nephrol vol. 165 , 299 - 309 .

Prowle JR, Echeverri JE, Ligabo EV, Ronco C, Bellomo R ( 2009 ) . Fluid balance and acute kidney injury . Nature Reviews Nephrology vol. 6 , ( 2 ) 107 - 115 .

Prowle JR, Bellomo R ( 2009 ) . Acute Kidney Injury: Specific Interventions and Drugs . Management of Acute Kidney Problems , Springer Nature

Prowle JR, Ishikawa K, May CN, Bellomo R ( 2009 ) . Renal Blood Flow during Acute Renal Failure in Man . Blood Purification vol. 28 , ( 3 ) 216 - 225 .

Liu YL, Prowle J, Licari E, Uchino S, Bellomo R ( 2009 ) . Changes in blood pressure before the development of nosocomial acute kidney injury . Nephrol Dial Transplant vol. 24 , ( 2 ) 504 - 511 .

Prowle J, Bellomo R, Buckmaster J, Gutteridge G, Hart G, Opdam H, Silvester W, Warrillow S ( 2008 ) . Continuous hemofiltration for anasarca: recovery of renal function after 71 liters of net ultrafiltration . Int J Artif Organs vol. 31 , ( 4 ) 367 - 370 .

Liu GY, Fairchild PJ, Smith RM, Prowle JR, Kioussis D, Wraith DC ( 1995 ) . Low avidity recognition of self-antigen by T cells permits escape from central tolerance . Immunity vol. 3 , ( 4 ) 407 - 415 .