Publications: Dr Amy Lewis
Rigoni A, Poulsom R, Jeffery R, Mehta S, Lewis A, Yau C, Giannoulatou E, Feakins R et al.(2017).
Separation of Dual Oxidase 2 and Lactoperoxidase Expression in Intestinal Crypts and Species Differences May Limit Hydrogen Peroxide Scavenging During Mucosal Healing in Mice and Humans. Inflamm Bowel Dis
vol. 24,
(1)
136-148.
Adam J, Ramracheya R, Chibalina MV, Ternette N, Hamilton A, Tarasov AI, Zhang Q, Rebelato E et al.(2017).
Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes. Cell Rep
vol. 20,
(13)
3135-3148.
Lewis A, Felice C, Kumagai T, Lai C, Singh K, Jeffery RR, Feakins R, Giannoulatou E et al.(2017).
The miR-200 family is increased in dysplastic lesions in ulcerative colitis patients. PLoS One
vol. 12,
(3)
e0173664-e0173664.
Nijhuis A, Thompson H, Adam J, Parker A, Gammon L, Lewis A, Bundy JG, Tomoyoshi S et al.(2017).
Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance. Human Molecular Genetics
Walton S-J, Lewis A, Jeffery R, Thompson H, Feakins R, Giannoulatou E, Yau C, Lindsay JO et al.(2016).
Familial adenomatous patients with desmoid tumours show increased expression of miR-34a in serum and high levels in tumours. Oncoscience
vol. 3,
(5-6)
173-185.
Rigoni A, Bongiovanni L, Burocchi A, Sangaletti S, Danelli L, Guarnotta C, Lewis A, Rizzo A et al.(2015).
Mast cells infiltrating inflamed or transformed gut alternatively sustain mucosal healing or tumor growth. Cancer Research
vol. 75,
(18)
3760-3770.
Lewis A, Nijhuis A, Mehta S, Kumagai T, Feakins R, Lindsay JO, Silver A(2015).
Intestinal fibrosis in crohn's disease: Role of microRNAs as fibrogenic modulators, serum biomarkers, and therapeutic targets. Inflammatory Bowel Diseases
vol. 21,
(5)
1141-1150.
Lewis A, Mehta S, Hanna LN, Rogalski LA, Jeffery R, Nijhuis A, Kumagai T, Biancheri P et al.(2015).
Low serum levels of microRNA-19 are associated with a stricturing Crohn's disease phenotype. Inflammatory Bowel Diseases
vol. 21,
(8)
1926-1934.
Felice C, Lewis A, Armuzzi A, Lindsay JO, Silver A(2015).
Review article: selective histone deacetylase isoforms as potential therapeutic targets in inflammatory bowel diseases. Aliment Pharmacol Ther
vol. 41,
(1)
26-38.
Shrikrishna D, Tanner RJ, Lee JY, Natanek A, Lewis A, Murphy PB, Hart N, Moxham J et al.(2014).
A randomized controlled trial of angiotensin-converting enzyme inhibition for skeletal muscle dysfunction in COPD. Chest
vol. 146,
(4)
932-940.
Nijhuis A, Biancheri P, Lewis A, Bishop CL, Giuffrida P, Chan C, Feakins R, Poulsom R et al.(2014).
In Crohn's disease fibrosis-reduced expression of the miR-29 family enhances collagen expression in intestinal fibroblasts. Clin Sci (Lond)
vol. 127,
(5)
341-350.
Donaldson A, Natanek SA, Lewis A, Man WD-C, Hopkinson NS, Polkey MI, Kemp PR(2013).
Increased skeletal muscle-specific microRNA in the blood of patients with COPD. Thorax
vol. 68,
(12)
1140-1149.
Lewis A, Riddoch-Contreras J, Natanek SA, Donaldson A, Man WD-C, Moxham J, Hopkinson NS, Polkey MI et al.(2012).
Downregulation of the serum response factor/miR-1 axis in the quadriceps of patients with COPD. Thorax
vol. 67,
(1)
26-34.
