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Research

Publications: Dr Paulo Baptista Ribeiro

Fulford AD, Holder MV, Frith D, Snijders AP, Tapon N, Ribeiro PS ( 2019 ) . Casein kinase 1 family proteins promote slimb-dependent expanded degradation . eLife vol. 8 ,
Fulford AD, Ribeiro PS ( 2019 ) . Drosophila Genetics: Analysis of Tissue Growth in Adult Tissues . Methods in Molecular Biology , vol. 1893 ,
Ferna¿dez-Espartero CH, Rizzo A, Fulford AD, Falo-Sanjuan J, Goutte-Gattat D, Ribeiro PS ( 2018 ) . Prp8 regulates oncogene-induced hyperplastic growth in drosophila . Development (Cambridge) vol. 145 , ( 22 )
Aflorei ED, Klapholz B, Chen C, Radian S, Dragu AN, Moderau N, Prodromou C, Ribeiro PS et al. ( 2018 ) . In vivo bioassay to test the pathogenicity of missense human AIP variants . Journal of Medical Genetics vol. 55 , ( 8 ) 522 - 529 .
Foxler DE, Bridge KS, Foster JG, Grevitt P, Curry S, Shah KM, Davidson KM, Nagano A et al. ( 2018 ) . A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia . EMBO Mol Med
Fulford A, Tapon N, Ribeiro PS ( 2018 ) . Upstairs, downstairs: spatial regulation of Hippo signalling . Current Opinion in Cell Biology vol. 51 , 22 - 32 .
Bridge KS, Shah KM, Li Y, Foxler DE, Wong SCK, Miller DC, Davidson KM, Foster JG et al. ( 2017 ) . Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins . Cell Reports vol. 20 , ( 1 ) 173 - 187 .
Orme MH, Liccardi G, Moderau N, Feltham R, Wicky-John S, Tenev T, Aram L, Wilson R et al. ( 2016 ) . The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles . Nature Communications vol. 7 ,
Ray RP, Matamoro-Vidal A, Ribeiro PS, Tapon N, Houle D, Salazar-Ciudad I, Thompson BJ ( 2015 ) . Patterned Anchorage to the Apical Extracellular Matrix Defines Tissue Shape in the Developing Appendages of Drosophila . Developmental Cell vol. 34 , ( 3 ) 310 - 322 .
Fletcher GC, Elbediwy A, Khanal I, Ribeiro PS, Tapon N, Thompson BJ ( 2015 ) . The Spectrin cytoskeleton regulates the Hippo signalling pathway . EMBO Journal vol. 34 , ( 7 ) 940 - 954 .
Ray RP, Ray RP, Matamoro-Vidal A, Matamoro-Vidal A, Ribeiro PS, Ribeiro PS, Tapon N, Houle D et al. ( 2014 ) . Patterned Anchorage to the Apical Extracellular Matrix Defines Tissue Shape in the Developing Appendages of Drosophila . Developmental Cell
Ribeiro P, Holder M, Frith D, Sneijders A, Tapon N ( 2014 ) . Crumbs promotes expanded recognition and degradation by the SCF(Slimb/β-TrCP) ubiquitin ligase . Proc Natl Acad Sci U S A vol. 111 , ( 19 ) E1980 - E1989 .
Meinander A, Runchel C, Tenev T, Chen L, Kim C-H, Ribeiro PS, Broemer M, Leulier F et al. ( 2012 ) . Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling . EMBO J vol. 31 , ( 12 ) 2770 - 2783 .
Ribeiro PS, Josué F, Wepf A, Wehr MC, Rinner O, Kelly G, Tapon N, Gstaiger M ( 2010 ) . Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling . Mol Cell vol. 39 , ( 4 ) 521 - 534 .
Lhocine N, Ribeiro PS, Buchon N, Wepf A, Wilson R, Tenev T, Lemaitre B, Gstaiger M et al. ( 2008 ) . PIMS Modulates Immune Tolerance by Negatively Regulating Drosophila Innate Immune Signaling . Cell Host and Microbe vol. 4 , ( 2 ) 147 - 158 .
Ribeiro PS, Kuranaga E, Tenev T, Leulier F, Miura M, Meier P ( 2007 ) . DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells . J Cell Biol vol. 179 , ( 7 ) 1467 - 1480 .
Leulier F, Ribeiro PS, Palmer E, Tenev T, Takahashi K, Robertson D, Zachariou A, Pichaud F et al. ( 2006 ) . Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery . Cell Death Differ vol. 13 , ( 10 ) 1663 - 1674 .