Skip to main content
Research

Publications: Dr Sarah McClelland

Mcclelland S, Tamura N, Shaikh N, Muliaditan D, Soliman T, McGuinness J, Maniati E, Moralli D et al. ( 2020 ) . Specific mechanisms of chromosomal instability indicate therapeutic sensitivities in high-grade serous ovarian carcinoma . Cancer Research
Graham TA, McClelland SE ( 2020 ) . Strands of evidence about cancer evolution . Nature vol. 583 , ( 7815 ) 207 - 209 .
Tovini L, McClelland SE ( 2020 ) . Towards restoring proper chromosome segregation and preventing ageing . EMBO Reports vol. 21 , ( 5 )
Dumont M, Gamba R, Gestraud P, Klaasen S, Worrall JT, De Vries SG, Boudreau V, Salinas-Luypaert C et al. ( 2020 ) . Human chromosome-specific aneuploidy is influenced by DNA-dependent centromeric features . EMBO J vol. 39 , ( 2 )
McClelland SE ( 2019 ) . Single-cell approaches to understand genome organisation throughout the cell cycle . Essays in Biochemistry vol. 63 , ( 2 ) 209 - 216 .
Johnson SC, McClelland SE ( 2019 ) . Watching cancer cells evolve through chromosomal instability . Nature vol. 570 , ( 7760 ) 166 - 167 .
Tijhuis AE, Johnson SC, McClelland SE ( 2019 ) . The emerging links between chromosomal instability (CIN), metastasis, inflammation and tumour immunity . Molecular Cytogenetics vol. 12 , ( 1 )
Tovini L, McClelland SE ( 2019 ) . Impaired CENP-E function renders large chromosomes more vulnerable to congression failure . Biomolecules vol. 9 , ( 2 )
Currie CE, Mora-Santos M, Smith CA, McClelland SE, McAinsh AD, Millar JB ( 2018 ) . Elucidating the role of Bub1 in human checkpoint signalling . MOLECULAR BIOLOGY OF THE CELL . vol. 29 ,
Worrall JT, Tamura N, Mazzagatti A, Shaikh N, van Lingen T, Bakker B, Spierings DCJ, Vladimirou E et al. ( 2018 ) . Non-random Mis-segregation of Human Chromosomes . Cell Reports vol. 23 , ( 11 ) 3366 - 3380 .
McClelland SE ( 2017 ) . Role of chromosomal instability in cancer progression . Endocr Relat Cancer vol. 24 , ( 9 ) T23 - T31 .
Worrall JT, McClelland SE ( 2016 ) . Determining the Missegregation Rates of Individual Human Chromosomes . CYTOGENETIC AND GENOME RESEARCH . vol. 148 , 131 - 131 .
Worrall JT, McClelland SE ( 2016 ) . Determining the missegregation rates of individual human chromosomes . MOLECULAR BIOLOGY OF THE CELL . vol. 27 ,
Tamura N, Shaikh N, McGuinness JR, Bowtell D, Balkwill F, Petermann E, McClelland SE ( 2016 ) . What drives chromosomal instability in high-grade serous ovarian cancer? . MOLECULAR BIOLOGY OF THE CELL . vol. 27 ,
Burrell RA, McClelland SE, Bartek J, Swanton C ( 2014 ) . Response to Bakhoum et al . Curr Biol vol. 24 , ( 4 )
Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller M-C, Shaikh N, Domingo E, Kanu N et al. ( 2013 ) . Replication stress links structural and numerical cancer chromosomal instability . Nature vol. 494 , ( 7438 ) 492 - 496 .
Burrell RA, McClelland SE, Endesfelder D, Rowan A, Schenk A, Sheffer M, Shaikh N, Domingo E et al. ( 2012 ) . Abstract 3105: Chromosome 18q encodes a chromosomal instability suppressor locus in colorectal cancer . 3105 - 3105 .
Burrell R, McClelland S, Juul N, Downward J, Szallasi Z, Szallasi Z, Swanton C, Swanton C ( 2009 ) . Regulators of Mitotic Transition Determine Paclitaxel Resistance In Vitro and Predict Poor Prognosis in Breast Cancer In Vivo . 2151 - 2151 .
Burrell RA, McClelland SE, Juul N, Downward J, Szallasi Z, Swanton C ( 2009 ) . Regulators of Mitotic Transition Determine Paclitaxel Resistance In Vitro and Predict Poor Prognosis in Breast Cancer In Vivo . CANCER RESEARCH . vol. 69 , 641S - 641S .
McClelland SE, Burrell RA, Swanton C ( 2009 ) . Chromosomal instability: a composite phenotype that influences sensitivity to chemotherapy . Cell Cycle vol. 8 , ( 20 ) 3262 - 3266 .