Publications:  Dr Alice Shia

Schmid P, Pinder S, Wheatley D, Zummit C, Macaskill E, Hu J, Price R, Bundred N et al. (2019). Abstract P2-08-02: Interaction of PIK3CA mutation subclasses with response to preoperative treatment with the PI3K inhibitor pictilisib in patients with estrogen receptor-positive breast cancer.

O'Leary K, Shia A, Schmid P(2017). Epigenetic Regulation of EMT in Non-Small Cell Lung Cancer. Curr Cancer Drug Targets vol. 18, (1) 89-96.

Lenihan C, Bouchekioua-Bouzaghou K, Abdulghani R, Chupin J, Shia A, Schmid P (2017). Abstract P3-03-12: CDK4/6 inhibitor resistant ER-positive cells remain dependent on estrogen signalling and retain sensitivity to endocrine therapy.

Lenihan C, Cavicchioli F, O¿Leary K, Shia A, Schmid P (2016). Abstract 2110: The role of VAV-interacting Kruppel-like factor (VIK) in resistance to palbociclib in estrogen receptor-positive breast cancer. 2110-2110.

Bouchekioua-Bouzaghou K, Lenihan C, Shia A, Wilkes E, Casado-Izquierdo P, Cutillas P, Schmid P (2016). Abstract 2819: Characterization of the mechanisms of early and later stages of resistance to the selective CDK4/6 inhibitor palbociclib. 2819-2819.

Schmid P, Pinder SE, Wheatley D, Macaskill J, Zammit C, Hu J, Price R, Bundred N et al.(2016). Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer. Journal of Clinical Oncology vol. 34, (17) 1987-1994.

Lenihan C, Bouchekioua-Bouzaghou K, Shia A, Wilkes E, Casado-Izquierdo P, Cutillas P, Schmid P (2016). Abstract P3-06-02: Characterization of resistance to the selective CDK4/6 inhibitor palbociclib in ER positive breast cancer.

Schmid P, Pinder S, Bundred N, Wheatley D, Macaskill J, Zammit C, Hu J, Price R et al. (2016). Abstract P5-13-01: Transcript analysis of PI3K and immune-related genes and gene signatures in the pre- and post-treatment samples from the window of opportunity study of anastrozole and anastrozole with pictilisib (GDC-0941) in patients with HR-positive early breast cancer (OPPORTUNE study).

O Leary K, Shia A, Cavicchioli F, Haley V, Comino A, Merlano M, Mauri F, Walter K et al.(2015). Identification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer. British Journal of Cancer

Schmid P, Pinder SE, Wheatley D, Macaskill J, Zammit C, Hu J, Price R, Bundred N et al. (2015). Abstract S2-03: Preoperative window of opportunity study of the PI3K inhibitor pictilisib (GDC-0941) plus anastrozole vs anastrozole alone in patients with ER+, HER2-negative operable breast cancer (OPPORTUNE study).

O'Leary K, Shia A, Cavicchioli F, Haley V, Comino A, Merlano M, Mauri F, Walter K et al.(2015). Identification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer. British Journal of Cancer vol. 113, (6) 970-978.

Progatzky F, Sangha NJ, Yoshida N, McBrien M, Cheung J, Shia A, Scott J, Marchesi JR et al. (2014). Intestinal inflammation induced by dietary cholesterol in Zebrafish. IMMUNOLOGY. vol. 143, 27-28.

Progatzky F, Sangha NJ, Yoshida N, McBrien M, Cheung J, Shia A, Scott J, Marchesi JR et al.(2014). Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation. Nature communications vol. 5,

Denne L, Shia A, Komulainen E, Haley V, Lenihan C, Cavicchioli F, O'Leary K, Schmid P(2013). Abstract P2-09-05: The potent anti-androgen enzalutamide demonstrates broad anti-tumour activity across all androgen receptor-positive triple-negative breast cancer subtypes.

Cavicchioli F, Shia A, O'Leary K, Haley V, Crook T, Thompson AM, Lackner M, Jones LJ et al. (2013). Sensitivity to glutamine deprivation is dependent on the interplay between epigenetic regulation of Glutamine synthetase (Glul) and induction of autophagy. EUROPEAN JOURNAL OF CANCER. vol. 49, S141-S141.

Haley V, Cavicchioli F, Shia A, O'Leary K, Balakrishnan L, Lo Nigro C, Schmid R (2013). miRNAs in resistance to lapatinib in HER2-positive breast cancer. EUROPEAN JOURNAL OF CANCER. vol. 49, S121-S121.

Cavicchioli F, Shia A, O'Leary K, Haley V, Crook T, Thompson A, Lackner M, Lo NC et al. (2012). Abstract P4-06-10: Epigenetic silencing of glutamine synthetase (Glul) defines glutamine depletion therapy.

Lara R, Mauri FA, Taylor H, Derua R, Shia A, Gray C, Nicols A, Shiner RJ et al.(2011). An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis. ONCOGENE vol. 30, (32) 3513-3521.

Shia AKH, Glittenberg M, Thompson G, Weber AN, Reichhart JM, Ligoxygakis P(2009). Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes. Journal of Cell Science vol. 122, (24) 4505-4515.

Shia AKH, Glittenberg M, Thompson G, Weber AN, Reichhart J-M, Ligoxygakis P(2009). Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes. J Cell Sci vol. 122, (Pt 24) 4505-4515.

Shia AKH, Gan GG, Jairaman S, Peh SC(2005). High frequency of germinal centre derivation in diffuse large B cell lymphoma from Asian patients. Journal of Clinical Pathology vol. 58, (9) 962-967.