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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Ms Ashley Pitt

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Le Bert N, Gill US, Hong M, Kunasegaran K, Tan DZM, Ahmad R, Cheng Y, Dutertre C-A et al. ( 2020 ) . Effects of Hepatitis B Surface Antigen on Virus-Specific and Global T Cells in Patients With Chronic Hepatitis B Virus infection . Gastroenterology vol. 159 , ( 2 ) 652 - 664 .
Bénéchet AP, De Simone G, Di Lucia P, Cilenti F, Barbiera G, Le Bert N, Fumagalli V, Lusito E et al. ( 2019 ) . Dynamics and genomic landscape of CD8+ T cells undergoing hepatic priming . Nature vol. 574 , ( 7777 ) 200 - 205 .
Le Bert N, Salimzadeh L, Gill US, Dutertre CA, Facchetti F, Tan A, Hung M, Novikov N et al. ( 2019 ) . Comparative characterization of B cells specific for HBV nucleocapsid and envelope proteins in patients with chronic hepatitis B . Journal of Hepatology
Gill US, Kennedy PTF ( 2019 ) . The impact of currently licensed therapies on viral and immune responses in chronic hepatitis B: Considerations for future novel therapeutics . J Viral Hepat vol. 26 , ( 1 ) 4 - 15 .
Chan HLY, Messinger D, Papatheodoridis GV, Cornberg M, Xie Q, Piratvisuth T, Ren H, Kennedy PT et al. ( 2018 ) . A baseline tool for predicting response to peginterferon alfa‐2a in HBeAg‐positive patients with chronic hepatitis B . Alimentary Pharmacology & Therapeutics vol. 48 , ( 5 ) 547 - 555 .
Foxler DE, Bridge KS, Foster JG, Grevitt P, Curry S, Shah KM, Davidson KM, Nagano A et al. ( 2018 ) . A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia . EMBO Mol Med
ALAZAWI W, Alexander M, Loomis AK, Fairburn-Beech J, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D et al. ( 2018 ) . Real world data reveal a diagnostic gap in non-alcoholic fatty liver disease . Real world data reveal a diagnostic gap in non-alcoholic fatty liver disease vol. 16 , ( 130 )
Koffas A, Dolman GE, Kennedy PT ( 2018 ) . Hepatitis B virus reactivation in patients treated with immunosuppressive drugs: a practical guide for clinicians . Clinical Medicine vol. 18 , ( 3 ) 212 - 218 .
Gill US, Pallett LJ, Kennedy PTF, Maini MK ( 2018 ) . Liver sampling: a vital window into HBV pathogenesis on the path to functional cure . Gut vol. 67 , ( 4 )
Bertoletti A, Kennedy PTF, Durantel D ( 2017 ) . HBV infection and HCC: the ‘dangerous liaisons’ . Gut vol. 67 , ( 5 )
Gill US, Kennedy PTF ( 2017 ) . Current therapeutic approaches for HBV infected patients . Journal of Hepatology vol. 67 , ( 2 ) 412 - 414 .
Kennedy PTF, Litwin S, Dolman GE, Bertoletti A, Mason WS ( 2017 ) . Immune Tolerant Chronic Hepatitis B: The Unrecognized Risks . Viruses vol. 9 , ( 5 )
Gill US, Kennedy PT ( 2015 ) . New insights in the management of chronic hepatitis B . Clinical Medicine vol. 15 , ( 2 ) 191 - 196 .
Conroy DM, Collins AJ, Kennedy PT ( 2014 ) . Re: Double Coaxial Microcatheter Technique for Transarterial Aneurysm Sac Embolization of Type II Endoleaks after Endovascular Abdominal Aortic Repair . Journal of Vascular and Interventional Radiology vol. 25 , ( 11 ) 1827 - 1828 .
Bertoletti A, Kennedy PT ( 2014 ) . The immune tolerant phase of chronic HBV infection: new perspectives on an old concept . Cellular & Molecular Immunology vol. 12 , ( 3 ) 258 - 263 .
Gill US, Kennedy PT ( 2014 ) . Chronic hepatitis B virus in young adults: the need for new approaches to management . Expert Review of Anti-infective Therapy vol. 12 , ( 9 ) 1045 - 1053 .
Kennedy PT, Gillespie JS, Acheson AG ( 2014 ) . An unlucky break . British Journal of Radiology vol. 72 , ( 854 ) 219 - 220 .
Sarri G, Westby M, Bermingham S, Hill-Cawthorne G, Thomas H ( 2013 ) . Diagnosis and management of chronic hepatitis B in children, young people, and adults: summary of NICE guidance . The BMJ vol. 346 , ( jun26 3 )
Schurich A, Pallett LJ, Lubowiecki M, Singh HD, Gill US, Kennedy PT, Nastouli E, Tanwar S et al. ( 2013 ) . The Third Signal Cytokine IL-12 Rescues the Anti-Viral Function of Exhausted HBV-Specific CD8 T Cells . PLOS Pathogens vol. 9 , ( 3 )
Peppa D, Gill US, Reynolds G, Easom NJW, Pallett LJ, Schurich A, Micco L, Nebbia G et al. ( 2012 ) . Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell–mediated deletion . Journal of Experimental Medicine vol. 210 , ( 1 ) 99 - 114 .
Nebbia G, Peppa D, Schurich A, Khanna P, Singh HD, Cheng Y, Rosenberg W, Dusheiko G et al. ( 2012 ) . Upregulation of the Tim-3/Galectin-9 Pathway of T Cell Exhaustion in Chronic Hepatitis B Virus Infection . PLOS ONE vol. 7 , ( 10 )
Das A, Ellis G, Pallant C, Lopes AR, Khanna P, Peppa D, Chen A, Blair P et al. ( 2012 ) . IL-10–Producing Regulatory B Cells in the Pathogenesis of Chronic Hepatitis B Virus Infection . The Journal of Immunology vol. 189 , ( 8 ) 3925 - 3935 .
Ji C, Sastry KSR, Tiefenthaler G, Cano J, Tang T, Ho ZZ, Teoh D, Bohini S et al. ( 2012 ) . Targeted delivery of interferon‐α to hepatitis B virus‐infected cells using T‐cell receptor‐like antibodies . Hepatology vol. 56 , ( 6 ) 2027 - 2038 .
Kennedy PTF, Sandalova E, Jo J, Gill U, Ushiro–Lumb I, Tan AT, Naik S, Foster GR et al. ( 2012 ) . Preserved T-Cell Function in Children and Young Adults With Immune-Tolerant Chronic Hepatitis B . Gastroenterology vol. 143 , ( 3 ) 637 - 645 .
Liu M, Miao T, Zhu H, Symonds ALJ, Li L, Schurich A, Maini MK, Zhang J et al. ( 2012 ) . IL-2-Engineered nano-APC Effectively Activates Viral Antigen-Mediated T Cell Responses from Chronic Hepatitis B Virus-Infected Patients . JOURNAL OF IMMUNOLOGY vol. 188 , ( 3 ) 1534 - 1543 .
Malik R, Kennedy P, Suri D, Brown A, Goldin R, Main J, Thomas H, Thursz M ( 2011 ) . The Role of Liver Fibrosis Assessment in the Management of Patients with Chronic Hepatitis B Infection: Lessons Learned from a Single Centre Experience . Hepatitis Research and Treatment vol. 2011 , ( 1 )
Schurich A, Khanna P, Lopes AR, Han KJ, Peppa D, Micco L, Nebbia G, Kennedy PTF et al. ( 2011 ) . Role of the coinhibitory receptor cytotoxic T lymphocyte antigen‐4 on apoptosis‐Prone CD8 T cells in persistent hepatitis B virus infection . Hepatology vol. 53 , ( 5 ) 1494 - 1503 .
Peppa D, Micco L, Javaid A, Kennedy PTF, Schurich A, Dunn C, Pallant C, Ellis G et al. ( 2010 ) . Blockade of Immunosuppressive Cytokines Restores NK Cell Antiviral Function in Chronic Hepatitis B Virus Infection . PLOS Pathogens vol. 6 , ( 12 )
Sastry KSR, Too CT, Kaur K, Gehring AJ, Low L, Javiad A, Pollicino T, Li L et al. ( 2010 ) . Targeting Hepatitis B Virus-Infected Cells with a T-Cell Receptor-Like Antibody . Journal of Virology vol. 85 , ( 5 ) 1935 - 1942 .
Kennedy PTF, Russo E, Kumar N, Powell N, Bansi D, Thillainayagam A, Vlavianos P, Westaby D ( 2010 ) . The safety and utility of prophylactic pancreatic duct stents in the prevention of post-ERCP pancreatitis: an analysis of practice in a single UK tertiary referral center . Surgical Endoscopy vol. 24 , ( 8 ) 1923 - 1928 .
Pasha Y, Blunt D, Kennedy PTF ( 2009 ) . The Pea, the yeast and the prostate . QJM vol. 103 , ( 4 ) 265 - 266 .
Kennedy PTF, Gehring AJ, Nowbath A, Selden C, Quaglia A, Dhillon A, Dusheiko G, Bertoletti A ( 2008 ) . The expression and function of NKG2D molecule on intrahepatic CD8+ T cells in chronic viral hepatitis . Journal of Viral Hepatitis vol. 15 , ( 12 ) 901 - 909 .
Das A, Hoare M, Davies N, Lopes AR, Dunn C, Kennedy PTF, Alexander G, Finney H et al. ( 2008 ) . Functional skewing of the global CD8 T cell population in chronic hepatitis B virus infection . Journal of Experimental Medicine vol. 205 , ( 9 ) 2111 - 2124 .
McConville RM, Kennedy PT, Collins AJ, Ellis PK ( 2008 ) . Failed Retrieval of an Inferior Vena Cava Filter During Pregnancy Because of Filter Tilt: Report of Two Cases . CardioVascular and Interventional Radiology vol. 32 , ( 1 ) 174 - 177 .
Kennedy PT, Phillips N, Chandrasekhar J, Jacobs R, Jacobs M, Dusheiko G ( 2008 ) . Potential and limitations of lamivudine monotherapy in chronic hepatitis B: evidence from genotyping . Liver International vol. 28 , ( 5 ) 699 - 704 .
PATRICK KENNEDY, KINGSTON AL ( 2008 ) . NICE guidelines and a treatment algorithm for the management of chronic hepatitis B: a review of 12 years experience in west London . NICE guidelines and a treatment algorithm for the management of chronic hepatitis B: a review of 12 years experience in west London
Dunn C, Brunetto M, Reynolds G, Christophides T, Kennedy PT, Lampertico P, Das A, Lopes AR et al. ( 2007 ) . Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell–mediated liver damage . Journal of Experimental Medicine vol. 204 , ( 3 ) 667 - 680 .
Gehring AJ, Sun D, Kennedy PTF, Hoen EN-T, Lim SG, Wasser S, Selden C, Maini MK et al. ( 2007 ) . The Level of Viral Antigen Presented by Hepatocytes Influences CD8 T-Cell Function . Journal of Virology vol. 81 , ( 6 ) 2940 - 2949 .
Johnston PW, Kennedy PT, Blair PH ( 2006 ) . Periaortitis complicating chronic aortic dissection . European Heart Journal vol. 28 , ( 4 ) 442 - 442 .
Kennedy PTF, Zakaria N, Modawi SB, Papadopoulou AM, Murray-Lyon I, du Bois RM, Andreyev HJN, Devlin J ( 2006 ) . Natural history of hepatic sarcoidosis and its response to treatment . European Journal of Gastroenterology & Hepatology vol. 18 , ( 7 ) 721 - 726 .
Kennedy PTF, Urbani S, Moses RA, Amadei B, Fisicaro P, Lloyd J, Maini MK, Dusheiko G et al. ( 2006 ) . The influence of T cell cross‐reactivity on HCV‐peptide specific human T cell response . Hepatology vol. 43 , ( 3 ) 602 - 611 .
Franzese O, Kennedy PTF, Gehring AJ, Gotto J, Williams R, Maini MK, Bertoletti A ( 2005 ) . Modulation of the CD8+-T-Cell Response by CD4+ CD25+ Regulatory T Cells in Patients with Hepatitis B Virus Infection . Journal of Virology vol. 79 , ( 6 ) 3322 - 3328 .
KENNEDY PATRICK, KINGSTON AL ( 2005 ) . Percutaneous ultrasound-guided thrombin injection of endoleaks . Percutaneous ultrasound-guided thrombin injection of endoleaks
Sun Z, Winder RJ, Kelly BE, Ellis PK, Kennedy PT, Hirst DG ( 2004 ) . Diagnostic Value of CT Virtual Intravascular Endoscopy in Aortic Stent-Grafting . Journal of Endovascular Therapy vol. 11 , ( 1 ) 13 - 25 .
Sun Z, Winder JR, Kelly BE, Ellis PK, Kennedy PT, Hirst DG ( 2004 ) . Assessment of VIE image quality using helical CT angiography: in vitro phantom study . Computerized Medical Imaging and Graphics vol. 28 , ( 1-2 ) 3 - 12 .
Ellis PK, Kennedy PT, Collins AJ, Blair PH ( 2003 ) . The Use of Direct Thrombin Injection to Treat a Type II Endoleak Following Endovascular Repair of Abdominal Aortic Aneurysm . CardioVascular and Interventional Radiology vol. 26 , ( 5 ) 482 - 484 .
Lewis HG, Morrison CM, Kennedy PT, Herbert KJ ( 2003 ) . Arterial Reconstruction Using the Basilic Vein from the Zone of Injury in Pediatric Supracondylar Humeral Fractures: A Clinical and Radiological Series . Plastic & Reconstructive Surgery vol. 111 , ( 3 ) 1159 - 1163 .
KENNEDY PATRICK, KINGSTON AL ( 2003 ) . Image-guided 25-gauge needle biopsy for thoracic lesions: diagnostic feasibility and safety . Image-guided 25-gauge needle biopsy for thoracic lesions: diagnostic feasibility and safety.
Kennedy PT, Goodacre BW, Wittich GR, vanSonnenberg E ( 2002 ) . Transosseous Access for Decompression of an Obstructed Pelvic Kidney . CardioVascular and Interventional Radiology vol. 25 , ( 4 ) 337 - 339 .
Ellis PK, Kennedy PT, Barros D'Sa AAB ( 2001 ) . Successful Exclusion of a High Internal Carotid Pseudoaneurysm Using the Wallgraft Endoprosthesis . CardioVascular and Interventional Radiology vol. 25 , ( 1 ) 68 - 69 .
Wittich GR, Goodacre BW, Kennedy PT, Mathew P ( 2001 ) . Anchoring a Migrating Inferior Vena Cava Stent with Use of a T-Fastener . Journal of Vascular and Interventional Radiology vol. 12 , ( 8 ) 994 - 996 .
Kennedy PT, Kelly IM, Loan WC, Boyd CS ( 2000 ) . Conscious Sedation and Analgesia for Routine Aortofemoral Arteriography: A Prospective Evaluation . Radiology vol. 216 , ( 3 ) 660 - 664 .
Kelly IM, Boyd CS, Kennedy PT ( 1999 ) . Adjuvant Urokinase Therapy in Percutaneous Drainage of a Multiloculated Splenic Abscess . Journal of Vascular and Interventional Radiology vol. 10 , ( 7 ) 919 - 923 .
KENNEDY PATRICK, KINGSTON AL ( 1999 ) . Early experience using duplex ultrasonography in the diagnosis of deep venous thrombosis; a prospective evaluation . Early experience using duplex ultrasonography in the diagnosis of deep venous thrombosis; a prospective evaluation
KENNEDY PATRICK, KINGSTON AL ( 1999 ) . Ultrasonography of intratesticular lesions: its role in clinical management . Ultrasonography of intratesticular lesions: its role in clinical management
KENNEDY PATRICK, KINGSTON AL ( 1998 ) . Association of posterior fossa dermoid cyst and Klippel-Feil syndrome . Association of posterior fossa dermoid cyst and Klippel-Feil syndrome
KENNEDY PATRICK, KINGSTON AL ( 1996 ) . Synovial chondromatosis of the cubometatarsal joint . Synovial chondromatosis of the cubometatarsal joint.
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