Publications: Miss Elena Pontarini

Emmerich K, Calcaterra F, Tang X, Chen G, Pontarini E, Ciceri R, Yang D, Joseph B et al. ( 2024 ) . Protocol for differentiation of monocytes and macrophages from human induced pluripotent stem cells . STAR Protocols vol. 5 , ( 3 )

Ruscitti P, Allanore Y, Baldini C, Barilaro G, Bartoloni Bocci E, Bearzi P, Bellis E, Berardicurti O et al. ( 2024 ) . Tailoring the treatment of inflammatory rheumatic diseases by a better stratification and characterization of the clinical patient heterogeneity. Findings from a systematic literature review and experts' consensus . Autoimmunity Reviews vol. 23 , ( 7-8 )

Simoncelli E, Colafrancesco S, Pontarini E, Villa M, Fischetti I, Mastromanno L, Izzo R, Gattamelata A et al. ( 2024 ) . AB0801 GLYCOLYSIS EXPRESSION IN LYMPHOCYTES INFILTRATING SJOGREN’S DISEASE SALIVARY GLANDS. A PRELIMINARY ANALYSIS ON THE EXPRESSION OF THE GLUCOSE TRANSPORTER GLUT-1 . Conference: Scientific Abstracts1694.2 - 161695 .

Pontarini E, Sciacca E, Cavallaro G, Galbraith D, Pulvirenti A, Hao LY, Sivils K, Lewis M et al. ( 2024 ) . AB0809 USER-FRIENDLY TOOL FOR EXPLORING RNA-SEQUENCE AND BIOMARKER DISCOVERY IN SJOGREN’S DISEASE: ANALYSE THE TWO BIGGEST DATASETS OF BLOOD AND SALIVARY GLAND RNA-SEQUENCING DATA USING R SHINY APPS . Conference: Scientific Abstracts1699.2 - 161699 .

Rasmussen A, Radziszewski M, Khatri B, Tessneer KL, Pontarini E, Bombardieri M, Rischmueller M, Wahren-Herlenius M et al. ( 2024 ) . OP0113 GENOME-WIDE ASSOCIATION STUDY OF Ro/SSA+ AND Ro/SSA-SJÖGREN’S CASES IN THE SJÖGREN’S GENETIC NETWORK (SGENE) DEMONSTRATES DIVERGENT GENETIC ARCHITECTURE IN PATIENT SUBPHENOTYPES . Conference: Scientific Abstracts38 - 39 .

Radziszewski M, Wiley MM, Khatri B, Rasmussen A, Tessneer KL, Kim K, Vital EM, Dand N et al. ( 2024 ) . OP0141 EXPLORING REGULATORY DYNAMICS: FUNCTIONAL SNPS IN THE PRDM1-ATG5 LOCUS IMPLICATED IN SYSTEMIC LUPUS ERYTHEMATOSUS AND SJÖGREN’S DISEASE . Conference: Scientific Abstracts39.2 - 3941 .

Surace A, Overend L, Sciacca E, Fossati-Jimack L, Jaworska E, Pontarini E, Bashford-Rogers RJM, Pitzalis C et al. ( 2024 ) . OP0242 SYNOVIAL TISSUE AND BLOOD DEEP B/T CELL PHENOTYPING EXPLAINS RESPONSE MECHANISMS TO RITUXIMAB IN RHEUMATOID ARTHRITIS IN R4RA . Conference: Scientific Abstracts13.2 - 1314 .

Corsiero E, Caliste M, Pontarini E, Dal Ferro M, Figini M, Luison E, Currado D, Perretti M et al. ( 2024 ) . POS0250 GENERATION AND VALIDATION OF A HUMAN IMMUNE scFv LIBRARY FROM SJÖGREN’S SYNDROME SALIVARY GLAND B-CELLS . Conference: Scientific Abstracts281.1 - 28281 .

Pontarini E, Rizzo MT, Liefers SC, Cavallaro G, Van der Vegt B, Colafrancesco S, Zabotti A, Quartuccio L et al. ( 2024 ) . POS0265 ESTABLISHING CONSISTENCY IN THE DIGITAL IMAGING ANALYSIS OF HISTOLOGICAL PARAMETERS IN SJOGREN’S DISEASE . Conference: Scientific Abstracts282.2 - 28283 .

Colafrancesco S, Simoncelli E, Pontarini E, Cavallaro G, Lucchesi D, Marino A, Buoncuore G, Barbati C et al. ( 2024 ) . POS0997 INFLAMMATION IN SJӦGREN DISEASE INDUCES SALIVARY GLAND EPITHELIAL CELLS (SGECS) METABOLIC REPROGRAMMING: FOCUS ON GLYCOLYSIS AND ITS REGULATION OF EPITHELIAL CELL ACTIVATION . Conference: Scientific Abstracts862 - 863 .

Mauro D, Lin X, Pontarini E, Wehr P, Guggino G, Tang Y, Deng C, Gandolfo S et al. ( 2024 ) . CD8+ tissue-resident memory T cells are expanded in primary Sjögren’s disease and can be therapeutically targeted by CD103 blockade . Annals of the Rheumatic Diseases vol. 83 , ( 10 ) 1345 - 1357 .

Nerviani A, Boutet M-A, Ghirardi GM, Goldmann K, Sciacca E, Rivellese F, Pontarini E, Prediletto E et al. ( 2024 ) . Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis . Nature Communications vol. 15 , ( 1 )

Pontarini E, Sciacca E, Chowdhury F, Grigoriadou S, Rivellese F, Murray‐Brown WJ, Lucchesi D, Fossati‐Jimack L et al. ( 2024 ) . Serum and Tissue Biomarkers Associated With Composite of Relevant Endpoints for Sjögren Syndrome (CRESS) and Sjögren Tool for Assessing Response (STAR) to B Cell–Targeted Therapy in the Trial of Anti–B Cell Therapy in Patients With Primary Sjögren Syndrome (TRACTISS) . Arthritis & Rheumatology vol. 76 , ( 5 ) 763 - 776 .

Duquesne J, Basseto L, Barnes M, Pontarini E, Adam C, Lazure T, Bombardieri M, Gallagher-Syed A et al. ( 2023 ) . Un modèle d’intelligence artificielle prédit le focus score et le diagnostic de la maladie de Sjögren à partir de biopsies de glandes salivaires . Revue du Rhumatisme vol. 90 ,

Chen G, Calcaterra F, Ma Y, Ping X, Pontarini E, Yang D, Oriolo F, Yu Z et al. ( 2023 ) . Derived myeloid lineage induced pluripotent stem as a platform to study human C-C chemokine receptor type 5Δ32 homozygotes . iScience vol. 26 , ( 11 )

Pitsillidou C, Muradore I, Pontarini E, Bertolotti M, Roberto A ( 2023 ) . A redox-based characterization of human immune cell subsets by polychromatic flow cytometry . STAR Protocols vol. 4 , ( 4 )

Pontarini E, Lucchesi D, Goldmann K, Lewis M, Song Q, Thomas E, Hao LY, Sivils K et al. ( 2023 ) . POS0292 TRANSCRIPTOMIC PROFILING OF SJOGREN’S SALIVARY GLANDS IDENTIFIES FOLLICULAR AND EXTRA-FOLLICULAR GENE SIGNATURES ASSOCIATED WITH RHEUMATOID FACTOR SEROPOSITIVITY . 388.2 - 38388 .

Fanti S, Stephenson E, Rocha-Vieira E, Protonotarios A, Kanoni S, Shahaj E, Longhi MP, Vyas VS et al. ( 2022 ) . Circulating c-Met–Expressing Memory T Cells Define Cardiac Autoimmunity . Circulation vol. 146 , ( 25 ) 1930 - 1945 .

Nayar S, Pontarini E, Campos J, Berardicurti O, Smith CG, Asam S, Gardner DH, Colafrancesco S et al. ( 2022 ) . Immunofibroblasts regulate LTα3 expression in tertiary lymphoid structures in a pathway dependent on ICOS/ICOSL interaction . Communications Biology vol. 5 , ( 1 )

Pontarini E, Coleby R, Bombardieri M ( 2021 ) . Cellular and molecular diversity in Sjogren’s syndrome salivary glands: Towards a better definition of disease subsets . Seminars in Immunology vol. 58 ,

de Wolff L, Arends S, Pontarini E, Bombardieri M, Bowman SJ, Bootsma H ( 2021 ) . Development and performance of the Clinical Trials ESSDAI (ClinTrialsESSDAI), consisting of frequently active clinical domains, in two randomised controlled trials in primary Sjögren's syndrome . Clinical and Experimental Rheumatology vol. 39 Suppl 133 , ( 6 ) 100 - 106 .

Coleby R, Lucchesi D, Pontarini E, Pitzalis C, Bombardieri M ( 2021 ) . Stepwise changes in the murine salivary gland immune response during virally-induced ectopic lymphoid structure formation . Clinical and Experimental Rheumatology vol. 39 Suppl 133 , ( 6 ) 39 - 48 .

Pontarini E, Chowdhury F, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Goldmann K, Fossati-Jimack L et al. ( 2021 ) . OP0136 RITUXIMAB PREVENTS THE PROGRESSION OF B-CELL DRIVEN INFLAMMATORY INFILTRATE IN THE MINOR SALIVARY GLANDS OF PRIMARY SJOGREN’S SYNDROME BY DOWNREGULATING IMMUNOLOGICAL PATHWAYS KEY IN ECTOPIC GERMINAL CENTRE ORGANIZATION: RESULTS FROM THE TRACTISS TRIAL . Annals of the Rheumatic Diseases vol. 80 , ( Suppl 1 ) 79 - 80 .

Pontarini E, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Fossati-Jimack L, Coleby R, Chowdhury F et al. ( 2021 ) . NKp30 Receptor Upregulation in Salivary Glands of Sjögren’s Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment . Frontiers in Immunology vol. 12 ,

Arends S, de Wolff L, van Nimwegen JF, Verstappen GMPJ, Vehof J, Bombardieri M, Bowman SJ, Pontarini E et al. ( 2021 ) . Composite of Relevant Endpoints for Sjögren's Syndrome (CRESS): development and validation of a novel outcome measure . The Lancet Rheumatology vol. 3 , ( 8 ) e553 - e562 .

Rivellese F, Pontarini E, Fossati-Jimack L, Moura RA, Romão VC, Fonseca JE, Nerviani A, Cubuk C et al. ( 2021 ) . OP0011 INTEGRATION OF FLOW AND DIGITAL CYTOMETRY IN EARLY TREATMENT-NAÏVE RHEUMATOID ARTHRITIS IDENTIFIES DISTINCT IMMUNOPHENOTYPES IN PERIPHERAL BLOOD AND DISEASE TISSUE . Annals of the Rheumatic Diseases vol. 80 , ( Suppl 1 ) 7.2 - 7.7 .

Arends S, de Wolff L, Van Nimwegen JF, Verstappen GM, Vehof J, Bombardieri M, Bowman SJ, Pontarini E et al. ( 2021 ) . OP0130 COMPOSITE OF RELEVANT ENDPOINTS IN SJÖGREN’S SYNDROME (CRESS): A COMPREHENSIVE TOOL FOR CLINICAL TRIALS . Annals of the Rheumatic Diseases vol. 80 , ( Suppl 1 ) 74.1 - 7475 .

de Wolff L, Arends S, Pontarini E, Bombardieri M, Bowman SJ, Bootsma H ( 2021 ) . Performance of the Clinical Trials ESSDAI (ClinTrialsESSDAI), an Adjusted ESSDAI Score, in Two Randomised Clinical Trials in Patients with Primary Sjogren's Syndrome . ARTHRITIS & RHEUMATOLOGY . vol. 73 , 646 - 649 .

Jimenez-Royo P, Bombardieri M, Ciurtin C, Kostapanos M, Tappuni AR, Jordan N, Saleem A, Fuller T et al. ( 2020 ) . Advanced imaging for quantification of abnormalities in the salivary glands of patients with primary Sjögren’s syndrome . Rheumatology vol. 60 , ( 5 )

Pontarini E, Verstappen GM, Grigoriadou S, Kroese FGM, Bootsma H, Bombardieri M ( 2020 ) . Blocking T cell co-stimulation in primary Sjögren's syndrome: rationale, clinical efficacy and modulation of peripheral and salivary gland biomarkers . Clinical and Experimental Rheumatology vol. 38 Suppl 126 , ( 4 ) 222 - 227 .

Bombardieri M, Argyropoulou OD, Ferro F, Coleby R, Pontarini E, Governato G, Lucchesi D, Fulvio G et al. ( 2020 ) . One year in review 2020: pathogenesis of primary Sjögren's syndrome . Clinical and Experimental Rheumatology vol. 38 Suppl 126 , ( 4 ) 3 - 9 .

Lucchesi D, Pontarini E, Donati V, Mandarano M, Sidoni A, Bartoloni E, Baldini C, Tappuni AR et al. ( 2020 ) . The use of digital image analysis in the histological assessment of Sjögren's syndrome salivary glands improves inter-rater agreement and facilitates multicentre data harmonisation . Clinical and Experimental Rheumatology vol. 38 Suppl 126 , ( 4 ) 180 - 188 .

Pontarini E, Murray-Brown WJ, Croia C, Lucchesi D, Conway J, Rivellese F, Fossati-Jimack L, Astorri E et al. ( 2020 ) . Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren’s syndrome with ectopic germinal centres and MALT lymphoma . Annals of the Rheumatic Diseases vol. 79 , ( 12 ) 1588 - 1599 .

Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill DG, Soria AD, Jones SA et al. ( 2020 ) . Impaired Interleukin‐27–Mediated Control of CD4+ T Cell Function Impact on Ectopic Lymphoid Structure Formation in Patients With Sjögren's Syndrome . Arthritis & Rheumatology vol. 72 , ( 9 ) 1559 - 1570 .

Rivellese F, Pontarini E, Pitzalis C ( 2020 ) . Tertiary Lymphoid Organs in Rheumatoid Arthritis . Curr Top Microbiol Immunol

Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill D, Soria AD, Jones S et al. ( 2020 ) . O31 IL-27 regulates the magnitude of ectopic germinal centres in experimental sialadenitis but fails to modulate IL-17 and IFNg production in CD4 T cells from patients with Sjögren's syndrome . Rheumatology . vol. 59 ,

Pontarini E, Verstappen GM, Grigoriadou S, Kroese FGM, Bootsma H, Bombardieri M ( 2020 ) . Blocking T cell co-stimulation in primary Sjogren's syndrome: rationale, clinical efficacy and modulation of peripheral and salivary gland biomarkers . CLINICAL AND EXPERIMENTAL RHEUMATOLOGY vol. 38 , ( 4 ) S222 - S227 .

Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill D, Soria AD, Jones S et al. ( 2020 ) . IL-27 REGULATES THE MAGNITUDE OF ECTOPIC GERMINAL CENTRES IN EXPERIMENTAL SIALADENITIS BUT FAILS TO MODULATE IL-17 AND IFNG PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJOGREN'S SYNDROME . RHEUMATOLOGY . vol. 59 ,

Bombardieri M, Argyropoulou OD, Ferro F, Coleby R, Pontarini E, Governato G, Lucchesi D, Fulvio G et al. ( 2020 ) . One year in review 2020: pathogenesis of primary Sjogren's syndrome . CLINICAL AND EXPERIMENTAL RHEUMATOLOGY vol. 38 , ( 4 ) S3 - S9 .

Lucchesi D, Pontarini E, Donati V, Mandarano M, Sidoni A, Bartoloni E, Baldini C, Tappuni AR et al. ( 2020 ) . The use of digital image analysis in the histological assessment of Sjogren's syndrome salivary glands improves inter-rater agreement and facilitates multicentre data harmonisation . CLINICAL AND EXPERIMENTAL RHEUMATOLOGY vol. 38 , ( 4 ) S180 - S188 .

Pucino V, Certo M, Bulusu V, Cucchi D, Goldmann K, Pontarini E, Haas R, Smith J et al. ( 2019 ) . Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring . Cell Metabolism

Grigoriadou S, Chowdhury F, Pontarini E, Tappuni A, Bowman SJ, Bombardieri M ( 2019 ) . B-cell depletion with rituximab in the treatment of primary Sjögren's syndrome: What have we learnt? . Clinical and Experimental Rheumatology vol. 37 , S217 - S224 .

Colafrancesco S, Priori R, Smith CG, Minniti A, Iannizzotto V, Pipi E, Lucchesi D, Pontarini E et al. ( 2019 ) . CXCL13 as biomarker for histological involvement in Sjögren’s syndrome . Rheumatology vol. 59 , ( 1 ) 165 - 170 .

Lucchesi D, Coleby R, Pontarini E, Prediletto E, Hill D, Soria AD, Rivellese F, Pitzalis C et al. ( 2019 ) . OP0276 DENDRITIC CELL-DERIVED IL-27 REGULATES THE MAGNITUDE OF INDUCIBLE ECTOPIC GERMINAL CENTRES BUT FAILS TO DOWNMODULATE IL-17 PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJÖGREN’S SYNDROME . Conference: Oral Presentations220.1 - 22220 .

Pontarini E, Brown WM, Croia C, Lucchesi D, Rivellese F, Fossati-Jimack L, Ruscitti P, Prediletto E et al. ( 2019 ) . OP0279 A UNIQUE IL-21 SIGNATURE CHARACTERIZES LESIONAL AND CIRCULATING T-FOLLICULAR HELPER CELLS IN SJÖGREN’S SYNDROME PATIENTS WITH ECTOPIC GERMINAL CENTRES AND MALT LYMPHOMA . Conference: Oral Presentations221.1 - 22221 .

Rivellese F, Manou-Stathopoulou S, Mauro D, Pontarini E, Lucchesi D, Congia M, Schafer P, Sutcliffe N et al. ( 2019 ) . THU0234 THE TRANSCRIPTION FACTORS IKAROS (IKZF1) AND AIOLOS (IKZF3) ARE EXPRESSED IN THE SALIVARY GLANDS OF SJÖGREN’S SYNDROME PATIENTS WITH LYMPHOID AGGREGATES AND MODULATE B CELL ACTIVATION IN VITRO . Conference: Poster Presentations394.2 - 39395 .

Nocturne G, Pontarini E, Bombardieri M, Mariette X ( 2019 ) . Lymphomas complicating primary Sjögren's syndrome: from autoimmunity to lymphoma . Rheumatology vol. 60 , ( 8 ) 3513 - 3521 .

Grigoriadou S, Chowdhury F, Pontarini E, Tappuni A, Bowman SJ, Bombardieri M ( 2019 ) . B-cell depletion with rituximab in the treatment of primary Sjogren's syndrome: what have we learnt? . CLINICAL AND EXPERIMENTAL RHEUMATOLOGY vol. 37 , ( 3 ) S217 - S224 .

Prediletto E, Pontarini E, Lucchesi D, Corsiero E, Pratesi F, Migliorini P, Pitzalis C, Bombardieri M ( 2019 ) . Synovial fluid fibroblast-like synoviocytes enhance long-term survival of EBV infected memory B cells in rheumatoid arthritis . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 49 , 791 - 791 .

Pontarini E, Lucchesi D, Fossati-Jimack L, Coleby R, Tentorio P, Croia C, Bombardieri M, Mavilio D ( 2018 ) . NK cell recruitment in salivary glands provides early viral control but is dispensable for tertiary lymphoid structure formation . Journal of Leukocyte Biology vol. 105 , ( 3 ) 589 - 602 .

Notarstefano C, Croia C, Pontarini E, Lucchesi D, Sutcliffe N, Tappuni A, Donati V, Pitzalis C et al. ( 2018 ) . A clinical and histopathological analysis of the anti-centromere antibody positive subset of primary Sjögren's syndrome . Clin Exp Rheumatol vol. 36 Suppl 112 , ( 3 ) 145 - 149 .

Mauro D, Tsang V, Lucey-Clayton I, Rivellese F, Pagani S, Alam F, Pontarini E, Nerviani A et al. ( 2018 ) . FRI0271 Dimethyl fumarate inhibits ube2l3 mediated tlr7 signalling and autoreactive b cell development in sle . Annals of the Rheumatic Diseases . Conference: FRIDAY, 15 JUNE 2018 vol. 77 ,

Pontarini E, Lucchesi D, Bombardieri M ( 2018 ) . Current Views on the Pathogenesis of Sjögren's Syndrome . Current Opinion in Rheumatology ( 2 ) 215 - 221 .

Pontarini E, Lucchesi D, Bombardieri M ( 2018 ) . Current views on the pathogenesis of Sjögren's syndrome . Current Opinion in Rheumatology vol. 30 , ( 2 ) 215 - 221 .

Lucchesi D, Pontarini E, Coleby R, Jones G, Hill D, Pitzalis C, Bombardieri M ( 2018 ) . P079 Interleukin-27 regulates the magnitude of the ectopic germinal centre response in a viral-inducible model of sialadenitis . Annals of the Rheumatic Diseases . Conference: Poster presentations vol. 77 ,

Notarstefano C, Croia C, Pontarini E, Lucchesi D, Sutcliffe N, Tappuni A, Donati V, Pitzalis C et al. ( 2018 ) . A clinical and histopathological analysis of the anti-centromere antibody positive subset of primary Sjogren's syndrome . CLINICAL AND EXPERIMENTAL RHEUMATOLOGY vol. 36 , ( 3 ) S145 - S149 .

Rivellese F, Mauro D, Congia M, Pontarini E, Schafer P, Bombardieri M, Pitzalis C, Lewis MJ ( 2018 ) . Expression and Functions of the Transcription Factors Ikaros and Aiolos in Sjogren's Syndrome and Systemic Lupus Erythematosus . ARTHRITIS & RHEUMATOLOGY . vol. 70 ,

Lucchesi D, Pontarini E, Coleby R, Jones GW, Hill DG, Pitzalis C, Bombardieri M ( 2018 ) . Interleukin-27 regulates the magnitude of the ectopic germinal centre response in a virus-induced murine model of sialadenitis . CLINICAL AND EXPERIMENTAL RHEUMATOLOGY . vol. 36 , S244 - S244 .

Corsiero E, Jagemann L, Pontarini E, Fossati-Jimack L, Pitzalis C, Bombardieri M ( 2018 ) . Single-cell VH and VL Ig gene analysis reveal clonal relationship between IgM plus neoplastic B cells and plasmablasts in SS patients with parotid MALT lymphoma . CLINICAL AND EXPERIMENTAL RHEUMATOLOGY . vol. 36 , S249 - S249 .

Pontarini E, Murray-Brown W, Croia C, Corsiero E, Fossati-Jimack L, Astorri E, Lucchesi D, Lepse N et al. ( 2018 ) . T follicular-helper cells (TFH) enrichment and follicular T regulatory cells (TFR) exclusion from ectopic germinal centers in salivary glands of Sjogren's Syndrome patients . CLINICAL AND EXPERIMENTAL RHEUMATOLOGY . vol. 36 , S291 - S291 .

Pontarini E, Murray-Brown W, Croia C, Astorri E, Lucchesi D, Lepse N, Sutcliffe N, Tappuni A et al. ( 2017 ) . OP0300 Enrichment of T follicular-helper cells (TFH) and exclusion of t follicular-regulatory cells (TFR) from ectoPIC germinal centers in salivary glands of sjogren's syndrome patients . Annals of the Rheumatic Diseases . Conference: Oral Presentations vol. 76 ,

Lucchesi D, Pontarini E, Pitzalis C, Mavilio D, Bombardieri M ( 2017 ) . MYELOID CELLS DRIVE EARLY INFLAMMATION AND ORCHESTRATE SALIVARY GLANDS TERTIARY LYMPHOID STRUCTURES FORMATION IN A MODEL OF INDUCIBLE SIALADENITIS . ANNALS OF THE RHEUMATIC DISEASES . Conference: EWRR ( Athens ) from: 02/03/2017 to: 04/03/2017 , vol. 76 , A4 - A4 .

Calcaterra F, Pontarini E, Guibin C, Dan Y, Yuchi M, Tentorio P, Carenza C, Mikulak J et al. ( 2017 ) . Development of iPSC-derived monocytes/macrophages: a new reliable tool to study rare diseases and for drug screening . EUROPEAN JOURNAL OF CLINICAL INVESTIGATION . vol. 47 , 147 - 148 .

Mauro D, Tsang V, Clayton-Lucey IA, Pagani S, Alam F, Pontarini E, Nerviani A, Pakozdi A et al. ( 2017 ) . Regulation of TLR7 Signalling By UBE2L3 Dependent Linear Ubiquitination Explains Dimethyl Fumarate Suppression of Autoreactive B Cell Development in SLE . ARTHRITIS & RHEUMATOLOGY . vol. 69 ,

Pontarini E, Brown WM, Croia C, Corsiero E, Lucchesi D, Astorri E, Sutcliffe N, Tappuni A et al. ( 2017 ) . T Follicular- Helper CELLS (TFH) Enrichment and T Follicular-Regulatory CELLS (TFR) Exclusion from Ectopic Germinal Centers in Salivary Glands of Sjogren's Syndrome Patients . ARTHRITIS & RHEUMATOLOGY . vol. 69 ,

Hudspeth K, Donadon M, Cimino M, Pontarini E, Tentorio P, Preti M, Hong M, Bertoletti A et al. ( 2015 ) . Human liver-resident CD56bright/CD16neg NK cells are retained within hepatic sinusoids via the engagement of CCR5 and CXCR6 pathways . Journal of Autoimmunity vol. 66 , 40 - 50 .

Pontarini E, Lucchesi D, Mavilio D, Bombardieri M ( 2015 ) . AB0169 Recruitment and Activation of NK Cells in the Salivary Glands Regulates Early Viral Control but is Dependable for Autoimmunity and Focal Lymphocytic Sialoadenitis in an Inducible Murine Model of Sjogren-Like Disease . Annals of the Rheumatic Diseases . vol. 74 ,

Pontarini E, Fabris M, Quartuccio L, Cappeletti M, Calcaterra F, Roberto A, Curcio F, Mavilio D et al. ( 2015 ) . Treatment with belimumab restores B cell subsets and their expression of B cell activating factor receptor in patients with primary Sjogren’s syndrome . Rheumatology vol. 54 , ( 8 ) 1429 - 1434 .

Pontarini E, Lucchesi D, Mavilio D, Bombardieri M ( 2015 ) . Recruitment and Activation of NK Cells in the Salivary Glands Regulates Early Viral Control but is Dependable for Autoimmunity and Focal Lymphocytic Sialoadenitis in an Inducible Murine Model of Sjogren-Like Disease . SCANDINAVIAN JOURNAL OF IMMUNOLOGY . vol. 81 , 426 - 426 .

Mikulak J, Bozzo L, Roberto A, Pontarini E, Tentorio P, Hudspeth K, Lugli E, Mavilio D ( 2014 ) . Dopamine Inhibits the Effector Functions of Activated NK Cells via the Upregulation of the D5 Receptor . The Journal of Immunology vol. 193 , ( 6 ) 2792 - 2800 .

Rusmini M, Griseri P, Matera I, Pontarini E, Ravazzolo R, Mavilio D, Ceccherini I ( 2014 ) . Expression Variability and Function of the RET Gene in Adult Peripheral Blood Mononuclear Cells . Journal of Cellular Physiology vol. 229 , ( 12 ) 2027 - 2037 .

Fabris M, Quartuccio L, Pontarini E, Zabotti A, Benucci M, Manfredi M, Biasi D, Ravagnani V et al. ( 2014 ) . AB0311 The 158vv fcgamma receptor iiia genotype predicts a positive response to rituximab in rheumatoid arthritis: Analysis in a large cohort of italian patients . Annals of the Rheumatic Diseases vol. 71 , ( Suppl 3 )

Quartuccio L, Maset M, De Maglio G, Pontarini E, Fabris M, Mariuzzi L, Pizzolitto S, Beltrami CA et al. ( 2014 ) . AB0760 Role of oral cyclophosphamide in the treatment of giant cell arteritis . Annals of the Rheumatic Diseases vol. 71 , ( Suppl 3 )

Quartuccio L, Fabris M, Pontarini E, Salvin S, Zabotti A, Benucci M, Manfredi M, Biasi D et al. ( 2014 ) . FRI0255 The 158vv fcgamma receptor 3a genotype is associated with response to rituximab in rheumatoid arthritis: results of an italian multicentre study . Annals of the Rheumatic Diseases vol. 72 , ( Suppl 3 )

Quartuccio L, Salvin S, Fabris M, Maset M, Corazza L, Pontarini E, Isola M, De Vita S ( 2013 ) . SAT0205 Blys up-regulation and salivary clonal B-cell expansion characterize sjögren’s syndrome-related lymphoproliferative disorders and correlate with the new ESSDAI score . Annals of the Rheumatic Diseases . vol. 71 ,

Fabris M, Dolcetti R, Pasini E, Quartuccio L, Pontarini E, Salvin S, Ponzoni M, Scott CA et al. ( 2014 ) . High prevalence of Chlamydophila psittaci subclinical infection in Italian patients with Sjögren's syndrome and parotid gland marginal zone B-cell lymphoma of MALT-type . Clinical and Experimental Rheumatology vol. 32 , ( 1 ) 61 - 65 .

Lucchesi D, Pontarini E, Pitzalis C, Bombardieri M ( 2014 ) . Innate immune system early activation precedes the formation of functional tertiary lymphoid structures in a novel model of salivary gland ectopic lymphoid neogenesis . IMMUNOLOGY vol. 143 , 95 - 95 .

Pontarini E, Lucchesi D, Bombardieri M, Mavilio D ( 2014 ) . Recruitment and activation of NK cells regulates early immune responses to viral infection in the salivary glands of an inducible murine model of Sjogren-like disease . IMMUNOLOGY vol. 143 , 93 - 93 .

Hudspeth K, Pontarini E, Tentorio P, Cimino M, Donadon M, Torzilli G, Lugli E, Della Bella S et al. ( 2013 ) . The role of natural killer cells in autoimmune liver disease: A comprehensive review . Journal of Autoimmunity vol. 46 , 55 - 65 .

Fabris M, Dolcetti R, Pasini E, Quartuccio L, Pontarini E, Ponzoni M, Scott CA, Curcio F et al. ( 2013 ) . High prevalence of Chlamydophila Psittaci subclinical infection in Italian patients with Sjögren's syndrome and parotid gland B‐cell lymphoma . The FASEB Journal . vol. 27 , 1087.6 - 1087.6 .

Quartuccio L, Fabris M, Pontarini E, Salvin S, Zabotti A, Benucci M, Manfredi M, Biasi D et al. ( 2013 ) . The 158VV Fcgamma receptor 3A genotype is associated with response to rituximab in rheumatoid arthritis: results of an Italian multicentre study . Annals of the Rheumatic Diseases vol. 73 , ( 4 )

Quartuccio L, Fabris M, Pontarini E, Salvin S, Zabotti A, Benucci M, Manfredi M, Biasi D et al. ( 2013 ) . THE 158VV FCGAMMA RECEPTOR 3A GENOTYPE IS ASSOCIATED WITH RESPONSE TO RITUXIMAB IN RHEUMATOID ARTHRITIS: RESULTS OF AN ITALIAN MULTICENTRE STUDY . ANNALS OF THE RHEUMATIC DISEASES . vol. 72 , 460 - 461 .

Fabris M, Quartuccio L, Vital E, Pontarini E, Salvin S, Fabro C, Zabotti A, Benucci M et al. ( 2012 ) . The TTTT B lymphocyte stimulator promoter haplotype is associated with good response to rituximab therapy in seropositive rheumatoid arthritis resistant to tumor necrosis factor blockers . Arthritis & Rheumatism vol. 65 , ( 1 ) 88 - 97 .

Stinco G, Fabris M, Pasini E, Pontarini E, Patriarca MM, Piccirillo F, De Vita S, Dolcetti R ( 2012 ) . Detection of DNA of Chlamydophila psittaci in subjects with psoriasis: a casual or a causal link? . British Journal of Dermatology vol. 167 , ( 4 ) 926 - 928 .

Quartuccio L, Salvin S, Fabris M, Maset M, Pontarini E, Isola M, De Vita S ( 2012 ) . BLyS upregulation in Sjögren’s syndrome associated with lymphoproliferative disorders, higher ESSDAI score and B-cell clonal expansion in the salivary glands . Rheumatology vol. 52 , ( 2 ) 276 - 281 .

Quartuccio L, Maset M, De Maglio G, Pontarini E, Fabris M, Mansutti E, Mariuzzi L, Pizzolitto S et al. ( 2012 ) . Role of oral cyclophosphamide in the treatment of giant cell arteritis . Rheumatology vol. 51 , ( 9 ) 1677 - 1686 .

Fabris M, De Vita S, Pasini E, Quartuccio L, Pontarini E, Lombardi S, Fabro C, Sarzi-Puttini P et al. ( 2011 ) . Chlamydophila psittaci subclinical infection in chronic polyarthritis . Clinical and Experimental Rheumatology vol. 29 , ( 6 ) 977 - 982 .

Ceccarelli F, Perricone C, Fabris M, Alessandri C, Iagnocco A, Fabro C, Pontarini E, De Vita S et al. ( 2011 ) . Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis . Arthritis Research & Therapy vol. 13 , ( 4 )

Fabris M, Quartuccio L, Lombardi S, Benucci M, Manfredi M, Saracco M, Atzeni F, Morassi P et al. ( 2011 ) . Study on the possible role of the -174G>C IL-6 promoter polymorphism in predicting response to rituximab in rheumatoid arthritis . Reumatismo vol. 62 , ( 4 ) 253 - 258 .

Quartuccio L, Fabris M, Maset M, Pontarini E, Zabotti A, De Vita S ( 2011 ) . BONE MARROW B-CELL CLONAL EXPANSION IN MIXED CRYOGLOBULINEMIA: ASSOCIATION WITH NEPHRITIS AND SWITCH INTO A POLYCLONAL PATTERN AFTER B-CELL DEPLETION . CLINICAL AND EXPERIMENTAL RHEUMATOLOGY . vol. 29 , 160 - 160 .

Fabris M, De Vita S, Blasone N, Visentini D, Pezzarini E, Pontarini E, Fabro C, Quartuccio L et al. ( 2010 ) . Serum levels of anti-CCP antibodies, anti-MCV antibodies and RF IgA in the follow-up of patients with rheumatoid arthritis treated with rituximab . Autoimmunity Highlights vol. 1 , ( 2 ) 87 - 94 .

Fabris M, Quartuccio L, Lombardi S, Saracco M, Atzeni F, Carletto A, Cimmino M, Fabro C et al. ( 2010 ) . The CC homozygosis of the −174G>C IL-6 polymorphism predicts a lower efficacy of rituximab therapy in rheumatoid arthritis . Autoimmunity Reviews vol. 11 , ( 5 ) 315 - 320 .

Fabris M, Panighel C, Blasone N, Pontarini E, Fabro C, Curcio F, Visentini D, Tonutti E et al. ( 2010 ) . BLyS Role in the Diagnosis and Prognosis of Neuroendocrine Tumors: Preliminary Results . ENDOCRINE REVIEWS . vol. 31 ,