Publications: Dr Felice Rivellese

Sciacca E, Surace AEA, Alaimo S, Pulvirenti A, Rivellese F, Goldmann K, Ferro A, Latora V et al. ( 2022 ) . Network analysis of synovial RNA sequencing identifies gene-gene interactions predictive of response in rheumatoid arthritis . Arthritis Research and Therapy vol. 24 , ( 1 )

Wang J, Conlon D, Rivellese F, Nerviani A, Lewis MJ, Housley W, Levesque MC, Cao X et al. ( 2022 ) . Synovial Inflammatory Pathways Characterize Anti-TNF–Responsive Rheumatoid Arthritis Patients . Arthritis and Rheumatology vol. 74 , ( 12 ) 1916 - 1927 .

Smolen JS, Landewé RBM, Bergstra SA, Kerschbaumer A, Sepriano A, Aletaha D, Caporali R, Edwards CJ et al. ( 2022 ) . EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update . Annals of the Rheumatic Diseases vol. 82 , ( 1 ) 3 - 18 .

Carlucci PM, Li J, Fava A, Deonaraine KK, Wofsy D, James JA, Putterman C, Diamond B et al. ( 2022 ) . High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership . Rheumatology (Oxford) vol. 61 , ( 11 ) 4335 - 4343 .

Prediletto E, Cubuk C, Pontarini E, Rivellese F, Nerviani A, Lucchesi D, Caliste M, Corsiero E et al. ( 2022 ) . Rheumatoid Synovial Fibroblasts Display Imprinted Memory of Their Synovial Endotype Which Can Be Plastically Modulated by B-cells Crosstalk . ARTHRITIS & RHEUMATOLOGY . vol. 74 , 1242 - 1244 .

Humby F, Durez P, Buch MH, Lewis MJ, Bombardieri M, John C, Rizvi H, Warren L et al. ( 2022 ) . Rituximab versus tocilizumab and B-cell status in TNF-alpha inadequate-responder rheumatoid arthritis patients: the R4-RA RCT .

Rivellese F, Surace AEA, Goldmann K, Sciacca E, Çubuk C, Giorli G, John CR, Nerviani A et al. ( 2022 ) . Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial . Nature Medicine vol. 28 , ( 6 ) 1256 - 1268 .

Surace A, Sciacca E, Goldmann K, Rivellese F, Cubuk C, Giorli G, Fossati-Jimack L, Ahmed M et al. ( 2022 ) . OP0077 SYNOVIAL RNA-SEQ ANALYSIS OF THE R4RA TRIAL IDENTIFIES SIGNATURES OF TREATMENT RESISTANCE AND REFRACTORY STATE IN RHEUMATOID ARTHRITIS . Annals of the Rheumatic Diseases vol. 81 , ( Suppl 1 ) 52.2 - 5253 .

Rivellese F, Cubuk C, Surace A, Goldmann K, Sciacca E, Giorli G, Nerviani A, Fossati-Jimack L et al. ( 2022 ) . OP0085 CELL LINEAGE-SPECIFIC TRANSCRIPT DECONVOLUTION OF SYNOVIAL BIOPSIES FROM THE R4RA TRIAL IDENTIFIES CELL POPULATIONS ASSOCIATED WITH RESPONSE TO RITUXIMAB AND TOCILIZUMAB . Annals of the Rheumatic Diseases vol. 81 , ( Suppl 1 ) 56.2 - 5657 .

Verhoef LM, Vivekanantham A, Berti A, Bolek EC, Smeele HT, Oztas M, Shoop-Worrall S, Zhao SS et al. ( 2022 ) . OP0305 THE EMERGING EULAR NETWORK (EMEUNET) PEER-REVIEW MENTORING PROGRAM: TEN YEARS OF INITIATIVE . Annals of the Rheumatic Diseases vol. 81 , ( Suppl 1 ) 202.1 - 20203 .

Prediletto E, Cubuk C, Pontarini E, Rivellese F, Nerviani A, Lucchesi D, Caliste M, Corsiero E et al. ( 2022 ) . POS0138 RHEUMATOID SYNOVIAL FIBROBLASTS DISPLAY IMPRINTED MEMORY OF THEIR SYNOVIAL ENDOTYPE WHICH CAN BE PLASTICALLY MODULATED BY B-CELLS CROSSTALK . Annals of the Rheumatic Diseases vol. 81 , ( Suppl 1 ) 296.1 - 29296 .

Pontarini E, Chowdhury F, Sciacca E, Grigoriadou S, Murray-Brown W, Rivellese F, Lucchesi D, Goldmann K et al. ( 2022 ) . POS0145 CLINICAL RESPONSE TO RITUXIMAB IS ASSOCIATED WITH PREVENTION OF B-CELL DRIVEN SALIVARY GLAND INFLAMMATION AND EPITHELIAL RESTORATION AS REVEALED BY MOLECULAR PATHOLOGY: RESULTS FROM THE TRACTISS TRIAL IN PRIMARY SJOGREN’S SYNDROME . Annals of the Rheumatic Diseases vol. 81 , ( Suppl 1 ) 299.2 - 29300 .

Nerviani A, Boutet MA, Ghirardi GM, Goldmann K, Sciacca E, Rivellese F, Pontarini E, Caliste M et al. ( 2022 ) . POS0441 IN-DEPTH ANALYSIS OF Axl AND MerTK EXPRESSION PATTERNS AND REGULATION BY BIOLOGIC TREATMENTS IN RHEUMATOID ARTHRITIS . Annals of the Rheumatic Diseases vol. 81 , ( Suppl 1 ) 475.2 - 47476 .

Zhang F, Jonsson AH, Nathan A, Wei K, Millard N, Xiao Q, Gutierrez-Arcelus M, Apruzzese W et al. ( 2022 ) . Cellular deconstruction of inflamed synovium defines diverse inflammatory phenotypes in rheumatoid arthritis .

Rivellese F, Pitzalis C ( 2022 ) . Cellular and molecular diversity in Rheumatoid Arthritis . Seminars in Immunology

Najm A, Costantino F, Alivernini S, Alunno A, Bianchi E, Bignall J, Boyce B, Canete JD et al. ( 2022 ) . EULAR points to consider for minimal reporting requirements in synovial tissue research in rheumatology . Annals of the Rheumatic Diseases

Alunno A, Rivellese F, Lauper K, Aletaha D, Buch MH, Gossec L, Mandl P, Machado PM et al. ( 2021 ) . EMerging EULAR NETwork (EMEUNET): a remarkable foundation for the future . RMD Open vol. 7 , ( 3 )

Sciacca E, Surace A, Alaimo S, Pulvirenti A, Rivellese F, Goldmann K, Ferro A, Latora V et al. ( 2021 ) . Harnessing gene-gene interactions via an RNA-Sequencing network analysis framework improves precision medicine prediction in rheumatoid arthritis .

Rivellese F, Pitzalis C ( 2021 ) . Introduction to the special issue: Cellular and molecular diversity in rheumatic autoimmune diseases . Seminars in Immunology vol. 58 ,

Pontarini E, Chowdhury F, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Goldmann K, Fossati-Jimack L et al. ( 2021 ) . OP0136 RITUXIMAB PREVENTS THE PROGRESSION OF B-CELL DRIVEN INFLAMMATORY INFILTRATE IN THE MINOR SALIVARY GLANDS OF PRIMARY SJOGREN’S SYNDROME BY DOWNREGULATING IMMUNOLOGICAL PATHWAYS KEY IN ECTOPIC GERMINAL CENTRE ORGANIZATION: RESULTS FROM THE TRACTISS TRIAL . Annals of the Rheumatic Diseases vol. 80 , ( Suppl 1 ) 79 - 80 .

Pontarini E, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Fossati-Jimack L, Coleby R, Chowdhury F et al. ( 2021 ) . NKp30 Receptor Upregulation in Salivary Glands of Sjögren’s Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment . Frontiers in Immunology vol. 12 ,

Pontarini E, Chowdhury F, Sciacca E, Grigoriadou SA, Rivellese F, Lucchesi D, Goldmann K, Fossati-Jimack L et al. ( 2021 ) . Rituximab Prevents the Progression of B-cell Driven Inflammatory Infiltrate in the Minor Salivary Glands of Primary Sjogren's Syndrome by Downregulating Immunological Pathways Key in Ectopic Germinal Centre Organization: Results from the TRACTISS Trial . ARTHRITIS & RHEUMATOLOGY . vol. 73 , 2065 - 2066 .

Boutet MA, Nerviani A, Ribera GL, Leone R, Sironi M, Hands R, Rivellese F, Del Prete A et al. ( 2021 ) . Pentraxin-3 (PTX3) circulating and synovial expression levels correlate with rheumatoid arthritis severity and tissue infiltration independently of the response to conventional treatments . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 66 - 66 .

Deonaraine KK, Carlucci PM, Fava A, Li J, Wofsy D, James JA, Putterman C, Diamond B et al. ( 2021 ) . Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network . Lupus Sci Med vol. 8 , ( 1 )

Boutet MA, Nerviani A, Lliso-Ribera G, Leone R, Sironi M, Hands R, Rivellese F, Del Prete A et al. ( 2021 ) . Circulating and Synovial Pentraxin-3 (PTX3) Expression Levels Correlate With Rheumatoid Arthritis Severity and Tissue Infiltration Independently of Conventional Treatments Response . Frontiers in Immunology vol. 12 ,

Kragstrup TW, Singh HS, Grundberg I, Nielsen ALL, Rivellese F, Mehta A, Goldberg MB, Filbin MR et al. ( 2021 ) . Plasma ACE2 predicts outcome of COVID-19 in hospitalized patients . PLoS ONE vol. 16 , ( 6 June 2021 )

Rivellese F, Pontarini E, Fossati-Jimack L, Moura RA, Romão VC, Fonseca JE, Nerviani A, Cubuk C et al. ( 2021 ) . OP0011 INTEGRATION OF FLOW AND DIGITAL CYTOMETRY IN EARLY TREATMENT-NAÏVE RHEUMATOID ARTHRITIS IDENTIFIES DISTINCT IMMUNOPHENOTYPES IN PERIPHERAL BLOOD AND DISEASE TISSUE . Annals of the Rheumatic Diseases vol. 80 , ( Suppl 1 ) 7.2 - 7.7 .

de Hooge M, Hanlon M, Alunno A, Sepriano A, Lauper K, Rivellese F ( 2021 ) . OP0077 THE EMERGING EULAR NETWORK (EMEUNET): AN INTERNATIONAL SURVEY REFLECTING ON A TEN-YEAR JOURNEY . Annals of the Rheumatic Diseases vol. 80 , ( Suppl 1 ) 41.2 - 4142 .

Varricchi G, Paolocci N, Rivellese F, Rengo G ( 2021 ) . Editorial: Smoldering Inflammation in Cardio-Immune-Metabolic Disorders . Frontiers in Physiology vol. 12 ,

Rivellese F, Manou-Stathopoulou S, Mauro D, Goldmann K, Pyne D, Rajakariar R, Gordon P, Schafer P et al. ( 2021 ) . Effects of targeting the transcription factors Ikaros and Aiolos on B cell activation and differentiation in systemic lupus erythematosus . Lupus Science and Medicine vol. 8 , ( 1 )

Giacomelli R, Afeltra A, Bartoloni E, Berardicurti O, Bombardieri M, Bortoluzzi A, Carubbi F, Caso F et al. ( 2021 ) . The growing role of precision medicine for the treatment of autoimmune diseases; results of a systematic review of literature and Experts’ Consensus . Autoimmunity Reviews vol. 20 , ( 2 )

Pitzalis C, Humby F, Rivellese F, Nerviani A, Lewis M ( 2021 ) . Rituximab versus Tocilizumab in anti-TNF inadequate responder patients with Rheumatoid Arthritis (R4RA): a stratified, biopsy-driven, multi-centre, randomised, open label, controlled clinical trial – 16 week outcomes Article (Randomised Controlled Trial) . The Lancet

Humby F, Durez P, Buch MH, Lewis MJ, Rizvi H, Rivellese F, Nerviani A, Giorli G et al. ( 2021 ) . Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial . The Lancet vol. 397 , ( 10271 ) 305 - 317 .

Pontarini E, Murray-Brown WJ, Croia C, Lucchesi D, Conway J, Rivellese F, Fossati-Jimack L, Astorri E et al. ( 2020 ) . Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren's syndrome with ectopic germinal centres and MALT lymphoma . Annals of the Rheumatic Diseases vol. 79 , ( 12 ) 1588 - 1599 .

Sciacca E, Surace A, Lewis M, Alaimo S, Latora V, Rivellese F, Pulvirenti A, Ferro A et al. ( 2020 ) . Novel Network Tool Highlights Key Features Associated with Disease Pathotypes and Response to Treatment in Early Rheumatoid Arthritis . ARTHRITIS & RHEUMATOLOGY . Conference: ACR Convergence 2020 vol. 72 ,

Rivellese F, Humby F, Giorli G, Nerviani A, Hands R, Fossati-Jimack L, Thorborn G, Lewis M et al. ( 2020 ) . Histo-pathological Cellular Markers of Treatment Response to Rituximab and Tocilizumab in Matched Pre- and Post-treatment Synovial Biopsies from the R4RA Randomised Clinical Trial in Rheumatoid Arthritis . ARTHRITIS & RHEUMATOLOGY . vol. 72 ,

Nerviani A, Boutet M-A, Ghirardi GM, Lliso-Ribera G, Rivellese F, Lewis M, Bombardieri M, Humby F et al. ( 2020 ) . MerTK Synovial Expression Correlates with Disease Activity and Treatment Response in Rheumatoid Arthritis Patients . ARTHRITIS & RHEUMATOLOGY . vol. 72 ,

Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill DG, Derrac Soria A, Jones SA et al. ( 2020 ) . Impaired Interleukin-27–Mediated Control of CD4+ T Cell Function Impact on Ectopic Lymphoid Structure Formation in Patients With Sjögren's Syndrome . Arthritis and Rheumatology vol. 72 , ( 9 ) 1559 - 1570 .

Rivellese F, Rossi FW, Giorli G, Napolitano F, de Paulis A, Pitzalis C ( 2020 ) . Persistence of Mast Cell-Positive Synovitis in Early Rheumatoid Arthritis Following Treatment With Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs . Frontiers in Pharmacology vol. 11 , 1051 - 1051 .

Rivellese F, Humby F, Lliso Ribera G, Nerviani A, Sciacca E, Giorli G, Hands R, Fossati-Jimack L et al. ( 2020 ) . OP0217 INVOLVEMENT OF LARGE JOINTS AT DISEASE PRESENTATION IS ASSOCIATED WITH DIVERSE HISTOPATHOLOGICAL FEATURES AND CLINICAL OUTCOMES IN EARLY RHEUMATOID ARTHRITIS . Annals of the Rheumatic Diseases . vol. 79 , 134.1 - 13135 .

Nerviani A, Boutet MA, Ghirardi GM, Lliso Ribera G, Rivellese F, Lewis M, Bombardieri M, Humby F et al. ( 2020 ) . THU0082 MERTK SYNOVIAL EXPRESSION CORRELATES WITH TREATMENT RESPONSE IN RHEUMATOID ARTHRITIS . Annals of the Rheumatic Diseases . vol. 79 , 253.1 - 25253 .

Rivellese F, Pontarini E, Pitzalis C ( 2020 ) . Tertiary Lymphoid Organs in Rheumatoid Arthritis . Curr Top Microbiol Immunol

Rivellese F, Prediletto E ( 2020 ) . ACE2 at the centre of COVID-19 from paucisymptomatic infections to severe pneumonia . Autoimmunity Reviews vol. 19 , ( 6 )

Nerviani A, Di Cicco M, Mahto A, Lliso-Ribera G, Rivellese F, Thorborn G, Hands R, Bellan M et al. ( 2020 ) . A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients . Frontiers in Immunology vol. 11 ,

Rossi FW, Rivellese F, Napolitano F, Mosella F, Selleri C, Montuori N, de Paulis A ( 2020 ) . Effects of Polyurethane Foam Dressings as an Add-on Therapy in the Management of Digital Ulcers in Scleroderma Patients . Transl Med UniSa vol. 22 , 10 - 14 .

Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A et al. ( 2020 ) . B CELL-RICH SYNOVITIS IN EARLY AND ESTABLISHED RHEUMATOID ARTHRITIS . RHEUMATOLOGY . vol. 59 ,

Nerviani A, Lliso-Ribera G, Boutet M-A, Goldmann K, Rivellese F, Kelly S, Bombardieri M, Lewis M et al. ( 2020 ) . HISTOLOGICAL AND MOLECULAR FEATURES OF THE DISEASED SYNOVIUM IN EARLY UNTREATED PSA IN COMPARISON WITH RA . RHEUMATOLOGY . vol. 59 ,

Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill D, Soria AD, Jones S et al. ( 2020 ) . IL-27 REGULATES THE MAGNITUDE OF ECTOPIC GERMINAL CENTRES IN EXPERIMENTAL SIALADENITIS BUT FAILS TO MODULATE IL-17 AND IFNG PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJOGREN'S SYNDROME . RHEUMATOLOGY . vol. 59 ,

Humby FC, Lewis M, Durez P, Buch MH, Bombardieri M, Rizvi H, Rivellese F, Fossati L et al. ( 2020 ) . O07 Randomised, open labelled clinical trial to investigate synovial mechanisms determining response: resistance to rituximab versus tocilizumab in RA patients failing TNF inhibitor therapy . Rheumatology . vol. 59 ,

Nerviani A, Lliso-Ribera G, Boutet M-A, Goldmann K, Rivellese F, Kelly S, Bombardieri M, Lewis M et al. ( 2020 ) . O20 Histological and molecular features of the diseased synovium in early untreated PsA in comparison with RA . Rheumatology . vol. 59 ,

Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill D, Soria AD, Jones S et al. ( 2020 ) . O31 IL-27 regulates the magnitude of ectopic germinal centres in experimental sialadenitis but fails to modulate IL-17 and IFNg production in CD4 T cells from patients with Sjögren's syndrome . Rheumatology . vol. 59 ,

Humby FC, Lewis M, Durez P, Buch MH, Bombardieri M, Rizvi H, Rivellese F, Fossati L et al. ( 2020 ) . RANDOMISED, OPEN LABELLED CLINICAL TRIAL TO INVESTIGATE SYNOVIAL MECHANISMS DETERMINING RESPONSE: RESISTANCE TO RITUXIMAB VERSUS TOCILIZUMAB IN RA PATIENTS FAILING TNF INHIBITOR THERAPY . RHEUMATOLOGY . vol. 59 , 3 - + .

Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A et al. ( 2020 ) . B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure . Arthritis and Rheumatology

Lliso-Ribera G, Humby F, Lewis M, Nerviani A, Mauro D, Rivellese F, Kelly S, Hands R et al. ( 2019 ) . Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: Results from the pathobiology of early arthritis cohort (PEAC) . Annals of the Rheumatic Diseases vol. 78 , ( 12 ) 1642 - 1652 .

Humby F, Buch MH, Durez P, Lewis M, Bombardieri M, Rizvi H, Kelly S, Fosatti L et al. ( 2019 ) . A Randomised, Open Labelled Clinical Trial to Investigate Synovial Mechanisms Determining Response - Resistance to Rituximab versus Tocilizumab in Rheumatoid Arthritis Patients Failing TNF Inhibitor Therapy . ARTHRITIS & RHEUMATOLOGY . vol. 71 ,

Rivellese F, Lliso-Ribera G, Nerviani A, Humby F, Pitzalis C ( 2019 ) . Persistence of B Cell-rich Synovitis Following Conventional Synthetic Disease Modifying Anti-Rheumatic Drug Treatment in Early Rheumatoid Arthritis Is Associated with Radiographic Progression Independently of Clinical Response . ARTHRITIS & RHEUMATOLOGY . vol. 71 ,

Lewis MJ, Barnes MR, Blighe K, Goldmann K, Rana S, Hackney JA, Ramamoorthi N, John CR et al. ( 2019 ) . Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes . Cell Reports vol. 28 , 2455 - 2470 .

Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Ribera GL, Nerviani A et al. ( 2019 ) . THU0058 B CELL SYNOVITIS AND CLINICAL PHENOTYPES IN RHEUMATOID ARTHRITIS AT DIFFERENT DISEASE STAGES . https://ard.bmj.com/content/78/Suppl_2 . Conference: Annual European Congress of Rheumatology, EULAR 2019 ( Madrid ) from: 12/06/2019 to: 15/06/2019 , 296.2 - 29297 .

Manou-Stathopoulou S, Rivellese F, Mauro D, Goldmann K, Pyne D, Schafer P, Bombardieri M, Pitzalis C et al. ( 2019 ) . AB0179 THE TRANSCRIPTION FACTORS IKZF1 AND IKZF3 CONTROL B CELL ACTIVATION AND DIFFERENTIATION IN SYSTEMIC LUPUS ERYTHEMATOSUS . Conference: Abstracts Accepted for Publication1548.1 - 151548 .

Lucchesi D, Coleby R, Pontarini E, Prediletto E, Hill D, Soria AD, Rivellese F, Pitzalis C et al. ( 2019 ) . OP0276 DENDRITIC CELL-DERIVED IL-27 REGULATES THE MAGNITUDE OF INDUCIBLE ECTOPIC GERMINAL CENTRES BUT FAILS TO DOWNMODULATE IL-17 PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJÖGREN’S SYNDROME . Conference: Oral Presentations220.1 - 22220 .

Pontarini E, Brown WM, Croia C, Lucchesi D, Rivellese F, Fossati-Jimack L, Ruscitti P, Prediletto E et al. ( 2019 ) . OP0279 A UNIQUE IL-21 SIGNATURE CHARACTERIZES LESIONAL AND CIRCULATING T-FOLLICULAR HELPER CELLS IN SJÖGREN’S SYNDROME PATIENTS WITH ECTOPIC GERMINAL CENTRES AND MALT LYMPHOMA . Conference: Oral Presentations221.1 - 22221 .

Mauro D, Rivellese F, Manou-Stathopoulou S, Goldmann K, Pyne D, Ciccia F, Pitzalis C, Lewis M ( 2019 ) . SAT0025 THE EFFECT OF DIMETHYL FUMARATE ON PLASMABLAST DIFFERENTIATION TRANSCRIPTIONAL PROGRAMMES IN SYSTEMIC LUPUS ERYTHEMATOSUS . Conference: SATURDAY, 15 JUNE 20191077.1 - 101077 .

Nerviani A, Humby F, Ribera GL, Rivellese F, Kelly S, Hands R, Pitzalis C ( 2019 ) . THU0092 DEFINING A LEARNING CURVE FOR CLINICIANS PERFORMING ULTRASOUND-GUIDED DEFINING A LEARNING CURVE FOR CLINICIANS PERFORMING ULTRASOUND-GUIDED NEEDLE SYNOVIAL BIOPSIES: A RETROSPECTIVE ANALYSIS OF THE EXPERIENCE AT THE EXPERIMENTAL MEDICINE AND RHEUMATOLOGY, QUEEN MARY UNIVERSITY OF LONDON . Conference: Poster Presentations317.1 - 31317 .

Rivellese F, Manou-Stathopoulou S, Mauro D, Pontarini E, Lucchesi D, Congia M, Schafer P, Sutcliffe N et al. ( 2019 ) . THU0234 THE TRANSCRIPTION FACTORS IKAROS (IKZF1) AND AIOLOS (IKZF3) ARE EXPRESSED IN THE SALIVARY GLANDS OF SJÖGREN’S SYNDROME PATIENTS WITH LYMPHOID AGGREGATES AND MODULATE B CELL ACTIVATION IN VITRO . Conference: Poster Presentations394.2 - 39395 .

Varricchi G, Pecoraro A, Loffredo S, Poto R, Rivellese F, Genovese A, Marone G, Spadaro G ( 2019 ) . Heterogeneity of human mast cells with respect to MRGPRX2 receptor expression and function . Frontiers in Cellular Neuroscience vol. 13 ,

Pecoraro A, Crescenzi L, Galdiero MR, Marone G, Rivellese F, Rossi FW, De Paulis A, Genovese A et al. ( 2019 ) . Immunosuppressive therapy with rituximab in common variable immunodeficiency . Clinical and Molecular Allergy vol. 17 , ( 1 )

Rivellese F, Rossi FW, Galdiero MR, Pitzalis C, de Paulis A ( 2019 ) . Mast cells in early rheumatoid arthritis . International Journal of Molecular Sciences vol. 20 , ( 8 )

Varricchi G, Loffredo S, Borriello F, Pecoraro A, Rivellese F, Genovese A, Spadaro G, Marone G ( 2019 ) . Superantigenic activation of human cardiac mast cells . International Journal of Molecular Sciences vol. 20 , ( 8 )

Manou-Stathopoulou S, Rivellese F, Mauro D, Goldmann K, Pyne D, Schafer P, Bombardieri M, Pitzalis C et al. ( 2019 ) . 235 IKZF1 and IKZF3 inhibition impairs B cell differentiation and modulates gene expression in systemic lupus erythematosus . Conference: Abstractsa174.2 - a1a175 .

Buonauro A, Sorrentino R, Esposito R, Nappi L, Lobasso A, Santoro C, Rivellese F, Sellitto V et al. ( 2019 ) . Three-dimensional echocardiographic evaluation of the right ventricle in patients with uncomplicated systemic lupus erythematosus . Lupus vol. 28 , ( 4 ) 538 - 544 .

Rivellese F, Lobasso A, Barbieri L, Liccardo B, de Paulis A, Rossi FW ( 2019 ) . Novel therapeutic approaches in rheumatoid arthritis: Role of janus kinases inhibitors . Current Medicinal Chemistry vol. 26 , ( 16 ) 2823 - 2843 .

Rivellese F, Mauro D, Nerviani A, Pagani S, Fossati-Jimack L, Messemaker T, Kurreeman FAS, Toes REM et al. ( 2018 ) . Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production . Annals of the Rheumatic Diseases vol. 77 , ( 12 ) 1773 - 1781 .

Bruni C, Frech T, Manetti M, Rossi FW, Furst DE, De Paulis A, Rivellese F, Guiducci S et al. ( 2018 ) . Vascular Leaking, a Pivotal and Early Pathogenetic Event in Systemic Sclerosis: Should the Door Be Closed? . Frontiers in Immunology vol. 9 , 2045 - 2045 .

Rivellese F, Mauro D, Congia M, Pontarini E, Schafer P, Bombardieri M, Pitzalis C, Lewis MJ ( 2018 ) . Expression and Functions of the Transcription Factors Ikaros and Aiolos in Sjogren's Syndrome and Systemic Lupus Erythematosus . ARTHRITIS & RHEUMATOLOGY . vol. 70 ,

Mauro D, Tsang V, Lucey-Clayton I, Rivellese F, Pagani S, Alam F, Pontarini E, Nerviani A et al. ( 2018 ) . FRI0271 Dimethyl fumarate inhibits ube2l3 mediated tlr7 signalling and autoreactive b cell development in sle . Annals of the Rheumatic Diseases . Conference: FRIDAY, 15 JUNE 2018 vol. 77 ,

Rivellese F, Nerviani A, Mauro D, Pagani S, Humby F, Pitzalis C ( 2018 ) . SAT0076 Synovial mast cells and responses to synthetic and biologic dmards in early and established rheumatoid arthritis . Annals of the Rheumatic Diseases . Conference: Saturday, 16 JUNE 2018 vol. 77 ,

Nerviani A, Mauro D, Pagani S, Lliso-Ribera G, Rivellese F, Lewis M, Bombardieri M, Humby F et al. ( 2018 ) . THU0061 Restricted axl synovial expression and increased cleavage of axl ectodomain correlate with highly inflamed synovitis and more severe rheumatoid arthritis . Annals of the Rheumatic Diseases . Conference: THURSDAY, 14 JUNE 2018 vol. 77 ,

Rivellese F, Congia M, Mauro D, Bombardieri M, Lewis M, Pitzalis C ( 2018 ) . THU0070 The transcription factors ikaros and aiolos are expressed in the synovial membrane of early rheumatoid arthritis patients in association with synovial lymphoid aggregates . Annals of the Rheumatic Diseases . Conference: THURSDAY, 14 JUNE 2018 vol. 77 ,

Varricchi G, Raap U, Rivellese F, Marone G, Gibbs BF ( 2018 ) . Human mast cells and basophils—How are they similar how are they different? . Immunological Reviews vol. 282 , ( 1 ) 8 - 34 .

Rossi FW, Mercurio V, Rivellese F, Lobasso A, Barbieri L, Tocchetti CG, De Paulis A, Marone G ( 2018 ) . Severe Aortic Valve Regurgitation in Relapsing Polychondritis . Journal of Clinical Rheumatology vol. 24 , ( 2 ) 109 - 111 .

Rauber S, Luber M, Weber S, Maul L, Soare A, Wohlfahrt T, Bozec A, Herrmann M et al. ( 2017 ) . IL-9-Producing Innate Lymphoid Cells - Keyplayers That Orchestrate Resolution of Chronic Inflammation in Arthritis . ARTHRITIS & RHEUMATOLOGY . vol. 69 ,

Rivellese F, Humby F, Pagani S, Nerviani A, Pitzalis C ( 2017 ) . Persistence of Mast Cell-Rich Synovitis Is Associated with Lack of Response to Synthetic Disease Modifying Anti-Rheumatic Drugs in Patients with Early Rheumatoid Arthritis . ARTHRITIS & RHEUMATOLOGY . vol. 69 ,

Nerviani A, Pagani S, Mauro D, Humby F, Kelly S, Rivellese F, Ribera GL, Lewis MJ et al. ( 2017 ) . Tyrosine Kinase Receptor Axl Is Down Regulated in Highly Inflamed Rheumatoid Synovium and Negatively Correlates with Markers of Disease Activity . ARTHRITIS & RHEUMATOLOGY . vol. 69 ,

Rauber S, Luber M, Weber S, Maul L, Soare A, Wohlfahrt T, Lin NY, DIetel K et al. ( 2017 ) . Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells . Nature Medicine vol. 23 , ( 8 ) 938 - 944 .

Rivellese F, Humby F, Nerviani A, Pagani S, Mauro D, de Paulis A, Marone G, Pitzalis C ( 2017 ) . FRI0030 Synovial mast cells identify patients with a severe phenotype in a cohort of dmard naÏve patients with early rheumatoid arthritis . Annals of the Rheumatic Diseases . Conference: Poster Presentations vol. 76 ,

Rivellese F, Nerviani A, Rossi FW, Marone G, Matucci-Cerinic M, de Paulis A, Pitzalis C ( 2017 ) . Mast cells in rheumatoid arthritis: friends or foes? . Autoimmunity Reviews vol. 16 , ( 6 ) 557 - 563 .

Rossi FW, Lobasso A, Selleri C, Matucci-Cerinic M, Rivellese F, Shoenfeld Y, de Paulis A ( 2017 ) . Autoimmune tautology in a complex case of poly-autoimmunity: Systemic sclerosis, autoimmune liver involvement, antiphospholipid syndrome and hashimoto’s thyroiditis . Israel Medical Association Journal vol. 19 , ( 3 ) 193 - 195 .

Marone G, Varricchi G, Loffredo S, Galdiero MR, Rivellese F, De Paulis A ( 2017 ) . Are Basophils and Mast Cells Masters in HIV Infection? . International Archives of Allergy and Immunology vol. 171 , ( 3-4 ) 158 - 165 .

Rossi FW, Prevete N, Rivellese F, Lobasso A, Napolitano F, Granata F, Selleri C, de Paulis A ( 2016 ) . HIV-1 Nef promotes migration and chemokine synthesis of human basophils and mast cells through the interaction with CXCR4 . Clinical and Molecular Allergy vol. 14 , ( 15 ) 1 - 9 .

Rossi FW, Prevete N, Rivellese F, Napolitano F, Montuori N, Postiglione L, Selleri C, de Paulis A ( 2016 ) . The Urokinase/Urokinase Receptor System in Mast Cells: Effects of its Functional Interaction with fMLF Receptors . Transl Med UniSa vol. 15 , 34 - 41 .

Rivellese F, Humby F, Kelly S, de Paulis A, Marone G, Pitzalis C ( 2016 ) . Synovial Mast Cells Associate with High Disease Activity and Predict Radiographic Progression at 12 Months in Patients with Early Rheumatoid Arthritis . ARTHRITIS & RHEUMATOLOGY . vol. 68 ,

Karkampouna S, Kreulen M, Obdeijn MC, Kloen P, Dorjée AL, Rivellese F, Chojnowski A, Clark I et al. ( 2016 ) . Connective Tissue Degeneration: Mechanisms of Palmar Fascia Degeneration (Dupuytren's Disease) . Curr Mol Biol Rep vol. 2 , ( 3 ) 133 - 140 .

Rivellese F, Humby F, Kelly S, Nerviani A, Mauro D, Rocher-Ros V, El Shikh ME, de Paulis A et al. ( 2016 ) . SYNOVIAL MAST CELLS CORRELATE WITH LOCAL AND SYSTEMIC INFLAMMATION AND ARE FUNCTIONALLY ASSOCIATED WITH ECTOPIC LYMPHOID STRUCTURES IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS . Presented at: EULAR 2016 ,

Rivellese F, Humby F, Kelly S, Rocher V, Pitzalis C ( 2016 ) . SYNOVIAL MAST CELLS CORRELATE WITH INFLAMMATION AND CELLULAR INFILTRATION AND ARE ASSOCIATED WITH ECTOPIC LYMPHOID STRUCTURES IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS . RHEUMATOLOGY . vol. 55 , 89 - 90 .

Llibre A, López-Macías C, Marafioti T, Mehta H, Partridge A, Kanzig C, Rivellese F, Galson JD et al. ( 2016 ) . LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation . J Immunol vol. 196 , ( 5 ) 2085 - 2094 .

Rivellese F, De Paulis A, Marone G, Pitzalis C, Toes REM ( 2016 ) . Reply . Arthritis and Rheumatology vol. 68 , ( 3 ) 769 - 770 .

Suurmond J, Rivellese F, Dorjée AL, Bakker AM, Rombouts YJPC, Rispens T, Wolbink G, Zaldumbide A et al. ( 2015 ) . Toll-like receptor triggering augments activation of human mast cells by anti-citrullinated protein antibodies . Annals of the Rheumatic Diseases vol. 74 , ( 10 ) 1915 - 1923 .

Rivellese F, Suurmond J, Habets K, Dorjée AL, Ramamoorthi N, Townsend MJ, De Paulis A, Marone G et al. ( 2015 ) . Ability of interleukin-33- and immune complex-triggered activation of human mast cells to down-regulate monocyte-mediated immune responses . Arthritis and Rheumatology vol. 67 , ( 9 ) 2343 - 2353 .

Rivellese F, Suurmond J, Habets K, Dorjée AL, de Paulis A, Marone G, Pitzalis C, Huizinga TW et al. ( 2015 ) . THU0024 Human Mast Cells Stimulated with IL-33 and Immune Complexes Down-Regulate Monocyte Activation in Rheumatoid Arthritis . Annals of the Rheumatic Diseases . vol. 74 ,

Rivellese F, Suurmond J, de Paulis A, Marone G, Huizinga TWJ, Toes REM ( 2014 ) . IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation . European Journal of Immunology vol. 44 , ( 10 ) 3045 - 3055 .

Rivellese F, Suurmond J, de Paulis A, Marone G, Huizinga TWJ, Toes REM ( 2014 ) . IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation . Eur J Immunol vol. 44 , ( 10 ) 3045 - 3055 .

Rivellese F, Suurmond J, de Paulis A, Marone G, Huizinga TW, Toes REM ( 2014 ) . Human basophils modulate monocyte activation . ALLERGY . vol. 69 , 59 - 59 .

Del Mastro A, Pelosi C, Lobasso A, Rivellese F, Genovese A, de Paulis A, Marone G ( 2014 ) . Macrophagic activation syndrome in adult-onset Still's disease: report of a complex case . ALLERGY . vol. 69 , 471 - 472 .

Suurmond J, Rivellese F, Dorjée AL, Bakker AM, Rombouts YJPC, Rispens T, Wolbink G, Zaldumbide A et al. ( 2014 ) . Toll-like receptor triggering augments activation of human mast cells by anti-citrullinated protein antibodies . Annals of the Rheumatic Diseases

Suurmond J, Stoop JN, Rivellese F, Bakker AM, Huizinga TWJ, Toes REM ( 2014 ) . Activation of human basophils by combined toll-like receptor- and FcεRI-triggering can promote Th2 skewing of naive T helper cells . European Journal of Immunology vol. 44 , ( 2 ) 386 - 396 .

Rivellese F, Prevete N, Rossi FW, Lamacchia D, Pelosi C, Marone G, de Paulis A ( 2013 ) . FRI0035 Expression and functions of vascular endothelial growth factor and angiopoietin receptors in human synovial mast cells . Annals of the Rheumatic Diseases . vol. 71 ,

Prevete N, Rossi FW, Rivellese F, Lamacchia D, Pelosi C, Lobasso A, Necchi V, Solcia E et al. ( 2013 ) . Helicobacter pylori HP(2-20) induces eosinophil activation and accumulation in superficial gastric mucosa and stimulates VEGF-α and TGF-β release by interacting with formyl-peptide receptors . International Journal of Immunopathology and Pharmacology vol. 26 , ( 3 ) 647 - 662 .

Cioffi A, Siani MC, Rivellese F, Spadaro G, Genovese A ( 2012 ) . Drug hypersensitivity reactions. Part II. Extra-cutaneous manifestations . Italian Journal of Allergy and Clinical Immunology vol. 22 , ( 3-4 ) 45 - 54 .

Spadaro G, Squeglia V, Pecoraro A, Galdiero M, Gravante C, Rivellese F, Marone G, Genovese A ( 2012 ) . Heart failure in Churg-Strauss Syndrome: a case responsive to high-dose intravenous immunoglobulins therapy . ALLERGY . vol. 67 , 559 - 560 .

Prevete N, Salzano FA, Rossi FW, Rivellese F, Dellepiane M, Guastini L, Mora R, Marone G et al. ( 2011 ) . Role(s) of formyl-peptide receptors expressed in nasal epithelial cells . Journal of Biological Regulators and Homeostatic Agents vol. 25 , ( 4 ) 553 - 564 .

Prevete N, Rossi F, Salerno F, Rivellese F, Salami A, Salzano F, Marone G, de Paulis A ( 2010 ) . Role of formyl-peptide receptors expressed on nasal epithelial cells in chronic rhinosinusitis . ALLERGY . vol. 65 , 119 - 119 .

Rossi F, Baldissara M, Prevete N, Rivellese F, Pirozzi F, Bonaduce D, De Paulis A, Marone G ( 2010 ) . Role of the TDI-echocardiography in cardiac evaluation of patients with autoimmune diseases . ALLERGY . vol. 65 , 113 - 113 .

De Paulis A, Prevete N, Rossi FW, Rivellese F, Salerno F, Delfino G, Liccardo B, Avilla E et al. ( 2009 ) . Helicobacter pylori Hp(2-20) promotes migration and proliferation of gastric epithelial cells by interacting with formyl peptide receptors in vitro and accelerates gastric mucosal healing in vivo . Journal of Immunology vol. 183 , ( 6 ) 3761 - 3769 .

Romano M, Prevete N, Rossi FW, Rivellese F, Salerno F, Delfino G, Liccardo B, Staibano S et al. ( 2009 ) . 669 H. pylori Peptide HP(2-20) Promotes Healing of Injured Gastric Mucosa By Interacting with Formyl-Peptyde Receptors . Gastroenterology . vol. 136 , a - 103 .

Romano M, Prevete N, Rossi FW, Rivellese F, Salerno F, Delfino G, Liccardo B, Staibano S et al. ( 2009 ) . H. pylori Peptide HP(2-20) Promotes Healing of Injured Gastric Mucosa By Interacting with Formyl-Peptyde Receptors . GASTROENTEROLOGY . vol. 136 , A103 - A103 .

Romano M, Prevete N, Rossi FW, Rivellese F, Salerno F, Delfino G, Liccardo B, Staibano S et al. ( 2009 ) . H. PYLORI PEPTIDE Hp(2-20) AND HEALING OF INJURED GASTRIC MUCOSA: ROLE OF FORMYL-PEPTIDE RECEPTORS . Digestive and Liver Disease vol. 41 ,

Prevete N, Delfino G, Rivellese F, Rossi F, Liccardo B, Marone G, de Paulis A ( 2008 ) . Pleiotropic roles of formyl-peptide receptors expressed on human basophils . ALLERGY . vol. 63 , 30 - 30 .