Publications: Dr Felice Rivellese
Faust HJ, Cheng T-Y, Korsunsky I, Watts GFM, Gal-Oz ST, Trim WV, Kongthong S, Jonsson AH et al.
(
2024
)
.
Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis
.
Nature Communications
vol.
15
,
(
1
)
Ruscitti P, Currado D, Rivellese F, Vomero M, Navarini L, Cipriani P, Pitzalis C, Giacomelli R
(
2024
)
.
Diminished expression of the ubiquitin-proteasome system in early treatment-naïve patients with rheumatoid arthritis and concomitant type 2 diabetes may be linked to IL-1 pathway hyper-activity; results from PEAC cohort
.
Arthritis Research & Therapy
vol.
26
,
(
1
)
Tsoi MF, Kearsley-Fleet L, Azadbakht N, Watson K, Hyrich KL, Bluett J, Sultan S, McParland C et al.
(
2024
)
.
Association between body weight and tocilizumab effectiveness in rheumatoid arthritis: results from the BSRBR-RA
.
Rheumatology
Law C, Wacleche VS, Cao Y, Pillai A, Sowerby J, Hancock B, Horisberger A, Bracero S et al.
(
2024
)
.
Publisher Correction: Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
.
Nature
vol.
632
,
(
8025
)
e6
-
e6
.
Ruscitti P, Allanore Y, Baldini C, Barilaro G, Bartoloni Bocci E, Bearzi P, Bellis E, Berardicurti O et al.
(
2024
)
.
Tailoring the treatment of inflammatory rheumatic diseases by a better stratification and characterization of the clinical patient heterogeneity. Findings from a systematic literature review and experts' consensus
.
Autoimmunity Reviews
vol.
23
,
(
7-8
)
Law C, Wacleche VS, Cao Y, Pillai A, Sowerby J, Hancock B, Horisberger A, Bracero S et al.
(
2024
)
.
Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus
.
Nature
vol.
631
,
(
8022
)
857
-
866
.
Dunlap G, Wagner A, Meednu N, Wang R, Zhang F, Ekabe JC, Jonsson AH, Wei K et al.
(
2024
)
.
Clonal associations between lymphocyte subsets and functional states in rheumatoid arthritis synovium
.
Nature Communications
vol.
15
,
(
1
)
Iaquinta FS, Sciacca E, Abatecola F, Fossati-Jimack L, Pitzalis C, Rivellese F
(
2024
)
.
POS0351 A POST-HOC ANALYSIS OF THE BIOPSY-DRIVEN, MULTICENTRE, RANDOMISED R4RA CLINICAL TRIAL REVEALS AN INNATE IMMUNE SIGNATURE IN MULTI-DRUG RESISTANT RHEUMATOID ARTHRITIS PATIENTS WITH A LYMPHO-MYELOID PATHOTYPE
.
Conference:
Scientific Abstracts302.2
-
30303
.
Weinand K, Sakaue S, Nathan A, Jonsson AH, Zhang F, Watts GFM, Al Suqri M, Zhu Z et al.
(
2024
)
.
The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis
.
Nature Communications
vol.
15
,
(
1
)
Corsiero E, Caliste M, Jagemann L, Fossati-Jimack L, Goldmann K, Cubuk C, Ghirardi GM, Prediletto E et al.
(
2024
)
.
Autoimmunity to stromal-derived autoantigens in rheumatoid ectopic germinal centers exacerbates arthritis and affects clinical response
.
Journal of Clinical Investigation
vol.
134
,
(
12
)
Sakaue S, Weinand K, Isaac S, Dey KK, Jagadeesh K, Kanai M, Watts GFM, Zhu Z et al.
(
2024
)
.
Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles
.
Nature Genetics
vol.
56
,
(
4
)
615
-
626
.
Nerviani A, Boutet M-A, Ghirardi GM, Goldmann K, Sciacca E, Rivellese F, Pontarini E, Prediletto E et al.
(
2024
)
.
Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis
.
Nature Communications
vol.
15
,
(
1
)
Pontarini E, Sciacca E, Chowdhury F, Grigoriadou S, Rivellese F, Murray‐Brown WJ, Lucchesi D, Fossati‐Jimack L et al.
(
2024
)
.
Serum and Tissue Biomarkers Associated With Composite of Relevant Endpoints for Sjögren Syndrome (CRESS) and Sjögren Tool for Assessing Response (STAR) to B Cell–Targeted Therapy in the Trial of Anti–B Cell Therapy in Patients With Primary Sjögren Syndrome (TRACTISS)
.
Arthritis & Rheumatology
vol.
76
,
(
5
)
763
-
776
.
Weisenfeld D, Zhang F, Donlin L, Jonsson AH, Apruzzese W, Campbell D, Network AMPPRS, Rao DA et al.
(
2024
)
.
Associations Between Rheumatoid Arthritis Clinical Factors and Synovial Cell Types and States
.
Arthritis & Rheumatology
vol.
76
,
(
3
)
356
-
362
.
Kang JB, Shen AZ, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta KA et al.
(
2023
)
.
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution
.
Nature Genetics
vol.
55
,
(
12
)
2255
-
2268
.
Boutet M-A, Nerviani A, Fossati-Jimack L, Hands-Greenwood R, Ahmed M, Rivellese F, Pitzalis C
(
2023
)
.
Comparative analysis of late-stage rheumatoid arthritis and osteoarthritis reveals shared histopathological features
.
Osteoarthritis and Cartilage
vol.
32
,
(
2
)
166
-
176
.
Iaquinta FS, Rivellese F, Pitzalis C
(
2023
)
.
Synovial biopsies for molecular definition of rheumatoid arthritis and treatment response phenotyping: where can we improve?
.
Expert Review of Molecular Diagnostics
vol.
23
,
(
12
)
1071
-
1076
.
Zhang F, Jonsson AH, Nathan A, Millard N, Curtis M, Xiao Q, Gutierrez-Arcelus M, Apruzzese W et al.
(
2023
)
.
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes
.
Nature
vol.
623
,
(
7987
)
616
-
624
.
Rivellese F, Nerviani A, Giorli G, Warren L, Jaworska E, Bombardieri M, Lewis MJ, Humby F et al.
(
2023
)
.
Stratification of biological therapies by pathobiology in biologic-naive patients with rheumatoid arthritis (STRAP and STRAP-EU): two parallel, open-label, biopsy-driven, randomised trials
.
The Lancet Rheumatology
vol.
5
,
(
11
)
e648
-
e659
.
Khmelevskaya A, Houtman M, Buerki K, Pauli C, Rivellese F, Prediletto E, Pitzalis C, Distler O et al.
(
2023
)
.
AB0062 ABUNDANCE AND ACTIVATION OF MEMORY B-CELLS CHARACTERIZE SYNOVITIS IN RHEUMATOID ARTHRITIS PATIENTS WITH EARLY TREATMENT RESPONSE
.
1210.1
-
121210
.
Rivellese F, Currado D, Giorli G, Prediletto E, Nerviani A, Khmelevskaya A, Micheroli R, Ospelt C et al.
(
2023
)
.
AB0340 MULTI-DRUG RESISTANT RA IS ASSOCIATED WITH HIGHER BASELINE DISEASE ACTIVITY, MULTI-MORBIDITY, AND LOWER QUALITY OF LIFE: ANALYSES FROM THE R4RA BIOPSY-DRIVEN CLINICAL TRIAL
.
1353
-
1354
.
Ruscitti P, Currado D, Rivellese F, Vomero M, Navarini L, Cipriani P, Pitzalis C, Giacomelli R
(
2023
)
.
POS1020 A DIMINISHED EXPRESSION OF THE UBIQUITIN-PROTEASOME SYSTEM IN PATIENTS WITH RHEUMATOID ARTHRITIS AND DIABETES IS LINKED TO IL-1 PATHWAY HYPER-ACTIVITY
.
826.2
-
82827
.
Mauro D, Manou-Stathopoulou S, Rivellese F, Sciacca E, Goldmann K, Tsang V, Lucey-Clayton I, Pagani S et al.
(
2023
)
.
UBE2L3 regulates TLR7-induced B cell autoreactivity in Systemic Lupus Erythematosus
.
Journal of Autoimmunity
vol.
136
,
Smolen JS, Landewé RBM, Bergstra SA, Kerschbaumer A, Sepriano A, Aletaha D, Caporali R, Edwards CJ et al.
(
2022
)
.
EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update
.
Annals of the Rheumatic Diseases
vol.
82
,
(
1
)
3
-
18
.
Rivellese F, Pitzalis C
(
2022
)
.
Introduction to the special issue: Cellular and molecular diversity in rheumatic autoimmune diseases
.
Seminars in Immunology
vol.
58
,
Wang J, Conlon D, Rivellese F, Nerviani A, Lewis MJ, Housley W, Levesque MC, Cao X et al.
(
2022
)
.
Synovial Inflammatory Pathways Characterize Anti‐TNF–Responsive Rheumatoid Arthritis Patients
.
Arthritis & Rheumatology
vol.
74
,
(
12
)
1916
-
1927
.
Humby F, Durez P, Buch MH, Lewis MJ, Bombardieri M, John C, Rizvi H, Warren L et al.
(
2022
)
.
Rituximab versus tocilizumab and B-cell status in TNF-alpha inadequate-responder rheumatoid arthritis patients:the R4-RA RCT
.
Efficacy and Mechanism Evaluation
vol.
9
,
(
7
)
1
-
58
.
Sciacca E, Surace AEA, Alaimo S, Pulvirenti A, Rivellese F, Goldmann K, Ferro A, Latora V et al.
(
2022
)
.
Network analysis of synovial RNA sequencing identifies gene-gene interactions predictive of response in rheumatoid arthritis
.
Arthritis Research & Therapy
vol.
24
,
(
1
)
Surace A, Sciacca E, Goldmann K, Rivellese F, Cubuk C, Giorli G, Fossati-Jimack L, Ahmed M et al.
(
2022
)
.
OP0077 SYNOVIAL RNA-SEQ ANALYSIS OF THE R4RA TRIAL IDENTIFIES SIGNATURES OF TREATMENT RESISTANCE AND REFRACTORY STATE IN RHEUMATOID ARTHRITIS
.
Annals of the Rheumatic Diseases
vol.
81
,
(
Suppl 1
)
52.2
-
5253
.
Rivellese F, Cubuk C, Surace A, Goldmann K, Sciacca E, Giorli G, Nerviani A, Fossati-Jimack L et al.
(
2022
)
.
OP0085 CELL LINEAGE-SPECIFIC TRANSCRIPT DECONVOLUTION OF SYNOVIAL BIOPSIES FROM THE R4RA TRIAL IDENTIFIES CELL POPULATIONS ASSOCIATED WITH RESPONSE TO RITUXIMAB AND TOCILIZUMAB
.
Annals of the Rheumatic Diseases
vol.
81
,
(
Suppl 1
)
56.2
-
5657
.
Verhoef LM, Vivekanantham A, Berti A, Bolek EC, Smeele HT, Oztas M, Shoop-Worrall S, Zhao SS et al.
(
2022
)
.
OP0305 THE EMERGING EULAR NETWORK (EMEUNET) PEER-REVIEW MENTORING PROGRAM: TEN YEARS OF INITIATIVE
.
Annals of the Rheumatic Diseases
vol.
81
,
(
Suppl 1
)
202.1
-
20203
.
Prediletto E, Cubuk C, Pontarini E, Rivellese F, Nerviani A, Lucchesi D, Caliste M, Corsiero E et al.
(
2022
)
.
POS0138 RHEUMATOID SYNOVIAL FIBROBLASTS DISPLAY IMPRINTED MEMORY OF THEIR SYNOVIAL ENDOTYPE WHICH CAN BE PLASTICALLY MODULATED BY B-CELLS CROSSTALK
.
Annals of the Rheumatic Diseases
vol.
81
,
(
Suppl 1
)
296.1
-
29296
.
Pontarini E, Chowdhury F, Sciacca E, Grigoriadou S, Murray-Brown W, Rivellese F, Lucchesi D, Goldmann K et al.
(
2022
)
.
POS0145 CLINICAL RESPONSE TO RITUXIMAB IS ASSOCIATED WITH PREVENTION OF B-CELL DRIVEN SALIVARY GLAND INFLAMMATION AND EPITHELIAL RESTORATION AS REVEALED BY MOLECULAR PATHOLOGY: RESULTS FROM THE TRACTISS TRIAL IN PRIMARY SJOGREN’S SYNDROME
.
Annals of the Rheumatic Diseases
.
vol.
81
,
299.2
-
29300
.
Nerviani A, Boutet MA, Ghirardi GM, Goldmann K, Sciacca E, Rivellese F, Pontarini E, Caliste M et al.
(
2022
)
.
POS0441 IN-DEPTH ANALYSIS OF Axl AND MerTK EXPRESSION PATTERNS AND REGULATION BY BIOLOGIC TREATMENTS IN RHEUMATOID ARTHRITIS
.
Annals of the Rheumatic Diseases
.
vol.
81
,
475.2
-
47476
.
Rivellese F, Surace AEA, Goldmann K, Sciacca E, Çubuk C, Giorli G, John CR, Nerviani A et al.
(
2022
)
.
Rituximab versus tocilizumab in rheumatoid arthritis: synovial biopsy-based biomarker analysis of the phase 4 R4RA randomized trial
.
Nature Medicine
vol.
28
,
(
6
)
1256
-
1268
.
Carlucci PM, Li J, Fava A, Deonaraine KK, Wofsy D, James JA, Putterman C, Diamond B et al.
(
2022
)
.
High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership
.
Rheumatology
vol.
61
,
(
11
)
4335
-
4343
.
Najm A, Costantino F, Alivernini S, Alunno A, Bianchi E, Bignall J, Boyce B, Cañete JD et al.
(
2022
)
.
EULAR points to consider for minimal reporting requirements in synovial tissue research in rheumatology
.
Annals of the Rheumatic Diseases
vol.
81
,
(
12
)
1640
-
1646
.
Rivellese F, Pitzalis C
(
2022
)
.
Cellular and molecular diversity in Rheumatoid Arthritis
.
Seminars in Immunology
Rivellese F, Pontarini E, Cubuk C, Nerviani A, Fossati-Jimack L, Surace A, Sciacca E, Goldmann K et al.
(
2022
)
.
Module Signatures of Synovial Single-cell States Identify Disease Phenotypes in Early Treatment-naive Rheumatoid Arthritis
.
ARTHRITIS & RHEUMATOLOGY
.
vol.
74
,
3345
-
3347
.
Pontarini E, Chowdhury F, Sciacca E, Grigoriadou S, Emery P, Ng WF, Sutcliffe N, Rivellese F et al.
(
2022
)
.
RITUXIMAB PREVENTS WORSENING OF B-CELL DRIVEN SALIVARY GLAND INFLAMMATION AND EXCRETORY FUNCTION IN PRIMARY SJOGREN'S SYNDROME: RESULTS FROM THE TRACTISS TRIAL
.
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
.
vol.
40
,
91
-
92
.
Prediletto E, Cubuk C, Pontarini E, Rivellese F, Nerviani A, Lucchesi D, Caliste M, Corsiero E et al.
(
2022
)
.
Rheumatoid Synovial Fibroblasts Display Imprinted Memory of Their Synovial Endotype Which Can Be Plastically Modulated by B-cells Crosstalk
.
ARTHRITIS & RHEUMATOLOGY
.
vol.
74
,
1242
-
1244
.
Alunno A, Rivellese F, Lauper K, Aletaha D, Buch MH, Gossec L, Mandl P, Machado PM et al.
(
2021
)
.
EMerging EULAR NETwork (EMEUNET): a remarkable foundation for the future
.
RMD Open
vol.
7
,
(
3
)
Pontarini E, Chowdhury F, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Goldmann K, Fossati-Jimack L et al.
(
2021
)
.
OP0136 RITUXIMAB PREVENTS THE PROGRESSION OF B-CELL DRIVEN INFLAMMATORY INFILTRATE IN THE MINOR SALIVARY GLANDS OF PRIMARY SJOGREN’S SYNDROME BY DOWNREGULATING IMMUNOLOGICAL PATHWAYS KEY IN ECTOPIC GERMINAL CENTRE ORGANIZATION: RESULTS FROM THE TRACTISS TRIAL
.
Annals of the Rheumatic Diseases
vol.
80
,
(
Suppl 1
)
79
-
80
.
Pontarini E, Sciacca E, Grigoriadou S, Rivellese F, Lucchesi D, Fossati-Jimack L, Coleby R, Chowdhury F et al.
(
2021
)
.
NKp30 Receptor Upregulation in Salivary Glands of Sjögren’s Syndrome Characterizes Ectopic Lymphoid Structures and Is Restricted by Rituximab Treatment
.
Frontiers in Immunology
vol.
12
,
Deonaraine KK, Carlucci PM, Fava A, Li J, Wofsy D, James JA, Putterman C, Diamond B et al.
(
2021
)
.
Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network
.
Lupus Science & Medicine
vol.
8
,
(
1
)
Boutet M-A, Nerviani A, Lliso-Ribera G, Leone R, Sironi M, Hands R, Rivellese F, Del Prete A et al.
(
2021
)
.
Circulating and Synovial Pentraxin-3 (PTX3) Expression Levels Correlate With Rheumatoid Arthritis Severity and Tissue Infiltration Independently of Conventional Treatments Response
.
Frontiers in Immunology
vol.
12
,
Kragstrup TW, Singh HS, Grundberg I, Nielsen AL-L, Rivellese F, Mehta A, Goldberg MB, Filbin MR et al.
(
2021
)
.
Plasma ACE2 predicts outcome of COVID-19 in hospitalized patients
.
PLOS ONE
vol.
16
,
(
6
)
Rivellese F, Pontarini E, Fossati-Jimack L, Moura RA, Romão VC, Fonseca JE, Nerviani A, Cubuk C et al.
(
2021
)
.
OP0011 INTEGRATION OF FLOW AND DIGITAL CYTOMETRY IN EARLY TREATMENT-NAÏVE RHEUMATOID ARTHRITIS IDENTIFIES DISTINCT IMMUNOPHENOTYPES IN PERIPHERAL BLOOD AND DISEASE TISSUE
.
Annals of the Rheumatic Diseases
vol.
80
,
(
Suppl 1
)
7.2
-
7.7
.
de Hooge M, Hanlon M, Alunno A, Sepriano A, Lauper K, Rivellese F
(
2021
)
.
OP0077 THE EMERGING EULAR NETWORK (EMEUNET): AN INTERNATIONAL SURVEY REFLECTING ON A TEN-YEAR JOURNEY
.
Annals of the Rheumatic Diseases
vol.
80
,
(
Suppl 1
)
41.2
-
4142
.
Varricchi G, Paolocci N, Rivellese F, Rengo G
(
2021
)
.
Editorial: Smoldering Inflammation in Cardio-Immune-Metabolic Disorders
.
Frontiers in Physiology
vol.
12
,
Rivellese F, Manou-Stathopoulou S, Mauro D, Goldmann K, Pyne D, Rajakariar R, Gordon P, Schafer P et al.
(
2021
)
.
Effects of targeting the transcription factors Ikaros and Aiolos on B cell activation and differentiation in systemic lupus erythematosus
.
Lupus Science & Medicine
vol.
8
,
(
1
)
Pitzalis C, Humby F, Rivellese F, Nerviani A, Lewis M
(
2021
)
.
Rituximab versus Tocilizumab in anti-TNF inadequate responder patients with Rheumatoid Arthritis (R4RA): a stratified, biopsy-driven, multi-centre, randomised, open label, controlled clinical trial – 16 week outcomes
Article (Randomised Controlled Trial)
.
The Lancet
Boutet MA, Nerviani A, Ribera GL, Leone R, Sironi M, Hands R, Rivellese F, Del Prete A et al.
(
2021
)
.
Pentraxin-3 (PTX3) circulating and synovial expression levels correlate with rheumatoid arthritis severity and tissue infiltration independently of the response to conventional treatments
.
EUROPEAN JOURNAL OF IMMUNOLOGY
.
vol.
51
,
66
-
66
.
Pontarini E, Chowdhury F, Sciacca E, Grigoriadou SA, Rivellese F, Lucchesi D, Goldmann K, Fossati-Jimack L et al.
(
2021
)
.
Rituximab Prevents the Progression of B-cell Driven Inflammatory Infiltrate in the Minor Salivary Glands of Primary Sjogren's Syndrome by Downregulating Immunological Pathways Key in Ectopic Germinal Centre Organization: Results from the TRACTISS Trial
.
ARTHRITIS & RHEUMATOLOGY
.
vol.
73
,
2065
-
2066
.
Humby F, Durez P, Buch MH, Lewis MJ, Rizvi H, Rivellese F, Nerviani A, Giorli G et al.
(
2021
)
.
Rituximab versus tocilizumab in anti-TNF inadequate responder patients with rheumatoid arthritis (R4RA): 16-week outcomes of a stratified, biopsy-driven, multicentre, open-label, phase 4 randomised controlled trial
.
The Lancet
vol.
397
,
(
10271
)
305
-
317
.
Giacomelli R, Afeltra A, Bartoloni E, Berardicurti O, Bombardieri M, Bortoluzzi A, Carubbi F, Caso F et al.
(
2020
)
.
The growing role of precision medicine for the treatment of autoimmune diseases; results of a systematic review of literature and Experts’ Consensus
.
Autoimmunity Reviews
vol.
20
,
(
2
)
Sciacca E, Surace A, Lewis M, Alaimo S, Latora V, Rivellese F, Pulvirenti A, Ferro A et al.
(
2020
)
.
Novel Network Tool Highlights Key Features Associated with Disease Pathotypes and Response to Treatment in Early Rheumatoid Arthritis
.
ARTHRITIS & RHEUMATOLOGY
.
Conference:
ACR Convergence 2020
vol.
72
,
Pontarini E, Murray-Brown WJ, Croia C, Lucchesi D, Conway J, Rivellese F, Fossati-Jimack L, Astorri E et al.
(
2020
)
.
Unique expansion of IL-21+ Tfh and Tph cells under control of ICOS identifies Sjögren’s syndrome with ectopic germinal centres and MALT lymphoma
.
Annals of the Rheumatic Diseases
vol.
79
,
(
12
)
1588
-
1599
.
Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill DG, Soria AD, Jones SA et al.
(
2020
)
.
Impaired Interleukin‐27–Mediated Control of CD4+ T Cell Function Impact on Ectopic Lymphoid Structure Formation in Patients With Sjögren's Syndrome
.
Arthritis & Rheumatology
vol.
72
,
(
9
)
1559
-
1570
.
Rivellese F, Rossi FW, Giorli G, Napolitano F, de Paulis A, Pitzalis C
(
2020
)
.
Persistence of Mast Cell-Positive Synovitis in Early Rheumatoid Arthritis Following Treatment With Conventional Synthetic Disease Modifying Anti-Rheumatic Drugs
.
Frontiers in Pharmacology
vol.
11
,
1051
-
1051
.
Rivellese F, Humby F, Lliso Ribera G, Nerviani A, Sciacca E, Giorli G, Hands R, Fossati-Jimack L et al.
(
2020
)
.
OP0217 INVOLVEMENT OF LARGE JOINTS AT DISEASE PRESENTATION IS ASSOCIATED WITH DIVERSE HISTOPATHOLOGICAL FEATURES AND CLINICAL OUTCOMES IN EARLY RHEUMATOID ARTHRITIS
.
Annals of the Rheumatic Diseases
.
vol.
79
,
134.1
-
13135
.
Nerviani A, Boutet MA, Ghirardi GM, Lliso Ribera G, Rivellese F, Lewis M, Bombardieri M, Humby F et al.
(
2020
)
.
THU0082 MERTK SYNOVIAL EXPRESSION CORRELATES WITH TREATMENT RESPONSE IN RHEUMATOID ARTHRITIS
.
Annals of the Rheumatic Diseases
.
vol.
79
,
253.1
-
25253
.
Rivellese F, Pontarini E, Pitzalis C
(
2020
)
.
Tertiary Lymphoid Organs in Rheumatoid Arthritis
.
Curr Top Microbiol Immunol
Rossi FW, Rivellese F, Napolitano F, Mosella F, Selleri C, Montuori N, de Paulis A
(
2020
)
.
Effects of Polyurethane Foam Dressings as an Add-on Therapy in the Management of Digital Ulcers in Scleroderma Patients
.
Translational Medicine UniSa
vol.
22
,
10
-
14
.
Nerviani A, Di Cicco M, Mahto A, Lliso-Ribera G, Rivellese F, Thorborn G, Hands R, Bellan M et al.
(
2020
)
.
A Pauci-Immune Synovial Pathotype Predicts Inadequate Response to TNFα-Blockade in Rheumatoid Arthritis Patients
.
Frontiers in Immunology
vol.
11
,
Humby FC, Lewis M, Durez P, Buch MH, Bombardieri M, Rizvi H, Rivellese F, Fossati L et al.
(
2020
)
.
O07 Randomised, open labelled clinical trial to investigate synovial mechanisms determining response: resistance to rituximab versus tocilizumab in RA patients failing TNF inhibitor therapy
.
Rheumatology
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vol.
59
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Nerviani A, Lliso-Ribera G, Boutet M-A, Goldmann K, Rivellese F, Kelly S, Bombardieri M, Lewis M et al.
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O20 Histological and molecular features of the diseased synovium in early untreated PsA in comparison with RA
.
Rheumatology
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vol.
59
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Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill D, Soria AD, Jones S et al.
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2020
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O31 IL-27 regulates the magnitude of ectopic germinal centres in experimental sialadenitis but fails to modulate IL-17 and IFNg production in CD4 T cells from patients with Sjögren's syndrome
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Rheumatology
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59
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Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A et al.
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2020
)
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P233 B cell-rich synovitis in early and established rheumatoid arthritis
.
Rheumatology
vol.
59
,
(
Supplement_2
)
Rivellese F, Prediletto E
(
2020
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ACE2 at the centre of COVID-19 from paucisymptomatic infections to severe pneumonia
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Autoimmunity Reviews
vol.
19
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6
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Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A et al.
(
2020
)
.
B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure
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Arthritis and Rheumatology
Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Lliso-Ribera G, Nerviani A et al.
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B CELL-RICH SYNOVITIS IN EARLY AND ESTABLISHED RHEUMATOID ARTHRITIS
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RHEUMATOLOGY
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59
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Nerviani A, Lliso-Ribera G, Boutet M-A, Goldmann K, Rivellese F, Kelly S, Bombardieri M, Lewis M et al.
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HISTOLOGICAL AND MOLECULAR FEATURES OF THE DISEASED SYNOVIUM IN EARLY UNTREATED PSA IN COMPARISON WITH RA
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RHEUMATOLOGY
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vol.
59
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Rivellese F, Humby F, Giorli G, Nerviani A, Hands R, Fossati-Jimack L, Thorborn G, Lewis M et al.
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2020
)
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Histo-pathological Cellular Markers of Treatment Response to Rituximab and Tocilizumab in Matched Pre- and Post-treatment Synovial Biopsies from the R4RA Randomised Clinical Trial in Rheumatoid Arthritis
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ARTHRITIS & RHEUMATOLOGY
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vol.
72
,
Lucchesi D, Coleby R, Pontarini E, Prediletto E, Rivellese F, Hill D, Soria AD, Jones S et al.
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2020
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IL-27 REGULATES THE MAGNITUDE OF ECTOPIC GERMINAL CENTRES IN EXPERIMENTAL SIALADENITIS BUT FAILS TO MODULATE IL-17 AND IFNG PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJOGREN'S SYNDROME
.
RHEUMATOLOGY
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vol.
59
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Nerviani A, Boutet M-A, Ghirardi GM, Lliso-Ribera G, Rivellese F, Lewis M, Bombardieri M, Humby F et al.
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MerTK Synovial Expression Correlates with Disease Activity and Treatment Response in Rheumatoid Arthritis Patients
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ARTHRITIS & RHEUMATOLOGY
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vol.
72
,
Humby FC, Lewis M, Durez P, Buch MH, Bombardieri M, Rizvi H, Rivellese F, Fossati L et al.
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2020
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RANDOMISED, OPEN LABELLED CLINICAL TRIAL TO INVESTIGATE SYNOVIAL MECHANISMS DETERMINING RESPONSE: RESISTANCE TO RITUXIMAB VERSUS TOCILIZUMAB IN RA PATIENTS FAILING TNF INHIBITOR THERAPY
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RHEUMATOLOGY
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3
-
+
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Lliso-Ribera G, Humby F, Lewis M, Nerviani A, Mauro D, Rivellese F, Kelly S, Hands R et al.
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Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC)
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Annals of the Rheumatic Diseases
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Lewis MJ, Barnes MR, Blighe K, Goldmann K, Rana S, Hackney JA, Ramamoorthi N, John CR et al.
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Molecular Portraits of Early Rheumatoid Arthritis Identify Clinical and Treatment Response Phenotypes
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Cell Reports
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Varricchi G, Pecoraro A, Loffredo S, Poto R, Rivellese F, Genovese A, Marone G, Spadaro G
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Heterogeneity of Human Mast Cells With Respect to MRGPRX2 Receptor Expression and Function
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Frontiers in Cellular Neuroscience
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13
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Rivellese F, Humby F, Bugatti S, Fossati-Jimack L, Rizvi H, Lucchesi D, Ribera GL, Nerviani A et al.
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THU0058 B CELL SYNOVITIS AND CLINICAL PHENOTYPES IN RHEUMATOID ARTHRITIS AT DIFFERENT DISEASE STAGES
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https://ard.bmj.com/content/78/Suppl_2
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Conference:
Annual European Congress of Rheumatology, EULAR 2019
(
Madrid
)
from:
12/06/2019
to:
15/06/2019
,
296.2
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29297
.
Manou-Stathopoulou S, Rivellese F, Mauro D, Goldmann K, Pyne D, Schafer P, Bombardieri M, Pitzalis C et al.
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2019
)
.
AB0179 THE TRANSCRIPTION FACTORS IKZF1 AND IKZF3 CONTROL B CELL ACTIVATION AND DIFFERENTIATION IN SYSTEMIC LUPUS ERYTHEMATOSUS
.
Conference:
Abstracts Accepted for Publication1548.1
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151548
.
Lucchesi D, Coleby R, Pontarini E, Prediletto E, Hill D, Soria AD, Rivellese F, Pitzalis C et al.
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2019
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.
OP0276 DENDRITIC CELL-DERIVED IL-27 REGULATES THE MAGNITUDE OF INDUCIBLE ECTOPIC GERMINAL CENTRES BUT FAILS TO DOWNMODULATE IL-17 PRODUCTION IN CD4 T CELLS FROM PATIENTS WITH SJÖGREN’S SYNDROME
.
Conference:
Oral Presentations220.1
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22220
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Pontarini E, Brown WM, Croia C, Lucchesi D, Rivellese F, Fossati-Jimack L, Ruscitti P, Prediletto E et al.
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2019
)
.
OP0279 A UNIQUE IL-21 SIGNATURE CHARACTERIZES LESIONAL AND CIRCULATING T-FOLLICULAR HELPER CELLS IN SJÖGREN’S SYNDROME PATIENTS WITH ECTOPIC GERMINAL CENTRES AND MALT LYMPHOMA
.
Conference:
Oral Presentations221.1
-
22221
.
Mauro D, Rivellese F, Manou-Stathopoulou S, Goldmann K, Pyne D, Ciccia F, Pitzalis C, Lewis M
(
2019
)
.
SAT0025 THE EFFECT OF DIMETHYL FUMARATE ON PLASMABLAST DIFFERENTIATION TRANSCRIPTIONAL PROGRAMMES IN SYSTEMIC LUPUS ERYTHEMATOSUS
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Conference:
SATURDAY, 15 JUNE 20191077.1
-
101077
.
Nerviani A, Humby F, Ribera GL, Rivellese F, Kelly S, Hands R, Pitzalis C
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2019
)
.
THU0092 DEFINING A LEARNING CURVE FOR CLINICIANS PERFORMING ULTRASOUND-GUIDED DEFINING A LEARNING CURVE FOR CLINICIANS PERFORMING ULTRASOUND-GUIDED NEEDLE SYNOVIAL BIOPSIES: A RETROSPECTIVE ANALYSIS OF THE EXPERIENCE AT THE EXPERIMENTAL MEDICINE AND RHEUMATOLOGY, QUEEN MARY UNIVERSITY OF LONDON
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Conference:
Poster Presentations317.1
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31317
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Rivellese F, Manou-Stathopoulou S, Mauro D, Pontarini E, Lucchesi D, Congia M, Schafer P, Sutcliffe N et al.
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.
THU0234 THE TRANSCRIPTION FACTORS IKAROS (IKZF1) AND AIOLOS (IKZF3) ARE EXPRESSED IN THE SALIVARY GLANDS OF SJÖGREN’S SYNDROME PATIENTS WITH LYMPHOID AGGREGATES AND MODULATE B CELL ACTIVATION IN VITRO
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Conference:
Poster Presentations394.2
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39395
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Pecoraro A, Crescenzi L, Galdiero MR, Marone G, Rivellese F, Rossi FW, de Paulis A, Genovese A et al.
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Immunosuppressive therapy with rituximab in common variable immunodeficiency
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Clinical and Molecular Allergy
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Mast Cells in Early Rheumatoid Arthritis
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International Journal of Molecular Sciences
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Varricchi G, Loffredo S, Borriello F, Pecoraro A, Rivellese F, Genovese A, Spadaro G, Marone G
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Superantigenic Activation of Human Cardiac Mast Cells
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International Journal of Molecular Sciences
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Manou-Stathopoulou S, Rivellese F, Mauro D, Goldmann K, Pyne D, Schafer P, Bombardieri M, Pitzalis C et al.
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235 IKZF1 and IKZF3 inhibition impairs B cell differentiation and modulates gene expression in systemic lupus erythematosus
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Buonauro A, Sorrentino R, Esposito R, Nappi L, Lobasso A, Santoro C, Rivellese F, Sellitto V et al.
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Three-dimensional echocardiographic evaluation of the right ventricle in patients with uncomplicated systemic lupus erythematosus
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A Randomised, Open Labelled Clinical Trial to Investigate Synovial Mechanisms Determining Response - Resistance to Rituximab versus Tocilizumab in Rheumatoid Arthritis Patients Failing TNF Inhibitor Therapy
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ARTHRITIS & RHEUMATOLOGY
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Rivellese F, Lobasso A, Barbieri L, Liccardo B, de Paulis A, Rossi FW
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Novel Therapeutic Approaches in Rheumatoid Arthritis: Role of Janus Kinases Inhibitors
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Persistence of B Cell-rich Synovitis Following Conventional Synthetic Disease Modifying Anti-Rheumatic Drug Treatment in Early Rheumatoid Arthritis Is Associated with Radiographic Progression Independently of Clinical Response
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ARTHRITIS & RHEUMATOLOGY
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Bruni C, Frech T, Manetti M, Rossi FW, Furst DE, De Paulis A, Rivellese F, Guiducci S et al.
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Vascular Leaking, a Pivotal and Early Pathogenetic Event in Systemic Sclerosis: Should the Door Be Closed?
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Mast cells in early rheumatoid arthritis associate with disease severity and support B cell autoantibody production
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Annals of the Rheumatic Diseases
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FRI0271 Dimethyl fumarate inhibits ube2l3 mediated tlr7 signalling and autoreactive b cell development in sle
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Annals of the Rheumatic Diseases
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SAT0076 Synovial mast cells and responses to synthetic and biologic dmards in early and established rheumatoid arthritis
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Annals of the Rheumatic Diseases
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Saturday, 16 JUNE 2018
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Nerviani A, Mauro D, Pagani S, Lliso-Ribera G, Rivellese F, Lewis M, Bombardieri M, Humby F et al.
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THU0061 Restricted axl synovial expression and increased cleavage of axl ectodomain correlate with highly inflamed synovitis and more severe rheumatoid arthritis
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Annals of the Rheumatic Diseases
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THU0070 The transcription factors ikaros and aiolos are expressed in the synovial membrane of early rheumatoid arthritis patients in association with synovial lymphoid aggregates
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Annals of the Rheumatic Diseases
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THURSDAY, 14 JUNE 2018
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77
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Rossi FW, Mercurio V, Rivellese F, Lobasso A, Barbieri L, Tocchetti CG, de Paulis A, Marone G
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Severe Aortic Valve Regurgitation in Relapsing Polychondritis
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Human mast cells and basophils—How are they similar how are they different?
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Rivellese F, Mauro D, Congia M, Pontarini E, Schafer P, Bombardieri M, Pitzalis C, Lewis MJ
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Expression and Functions of the Transcription Factors Ikaros and Aiolos in Sjogren's Syndrome and Systemic Lupus Erythematosus
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Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells
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Rivellese F, Humby F, Nerviani A, Pagani S, Mauro D, de Paulis A, Marone G, Pitzalis C
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FRI0030 Synovial mast cells identify patients with a severe phenotype in a cohort of dmard naÏve patients with early rheumatoid arthritis
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Annals of the Rheumatic Diseases
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76
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Rivellese F, Nerviani A, Rossi FW, Marone G, Matucci-Cerinic M, de Paulis A, Pitzalis C
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Mast cells in rheumatoid arthritis: friends or foes?
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Rossi FW, Lobasso A, Selleri C, Matucci-Cerinic M, Rivellese F, Shoenfeld Y, de Paulis A
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Autoimmune Tautology in a Complex Case of Polyautoimmunity: Systemic Sclerosis, Autoimmune Liver Involvement, Antiphospholipid Syndrome and Hashimoto's Thyroiditis
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IL-9-Producing Innate Lymphoid Cells - Keyplayers That Orchestrate Resolution of Chronic Inflammation in Arthritis
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Rivellese F, Humby F, Pagani S, Nerviani A, Pitzalis C
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Persistence of Mast Cell-Rich Synovitis Is Associated with Lack of Response to Synthetic Disease Modifying Anti-Rheumatic Drugs in Patients with Early Rheumatoid Arthritis
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ARTHRITIS & RHEUMATOLOGY
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Nerviani A, Pagani S, Mauro D, Humby F, Kelly S, Rivellese F, Ribera GL, Lewis MJ et al.
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Tyrosine Kinase Receptor Axl Is Down Regulated in Highly Inflamed Rheumatoid Synovium and Negatively Correlates with Markers of Disease Activity
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Are Basophils and Mast Cells Masters in HIV Infection?
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Rossi FW, Prevete N, Rivellese F, Lobasso A, Napolitano F, Granata F, Selleri C, de Paulis A
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HIV-1 Nef promotes migration and chemokine synthesis of human basophils and mast cells through the interaction with CXCR4
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The Urokinase/Urokinase Receptor System in Mast Cells: Effects of its Functional Interaction with fMLF Receptors
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Connective Tissue Degeneration: Mechanisms of Palmar Fascia Degeneration (Dupuytren's Disease)
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SYNOVIAL MAST CELLS CORRELATE WITH LOCAL AND SYSTEMIC INFLAMMATION AND ARE FUNCTIONALLY ASSOCIATED WITH ECTOPIC LYMPHOID STRUCTURES IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS
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EULAR 2016
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Rivellese F, Humby F, Kelly S, Rocher V, Pitzalis C
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071 Synovial Mast Cells Correlate with Inflammation and Cellular Infiltration and are Associated with Ectopic Lymphoid Structures in Patients with Early Rheumatoid Arthritis
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Llibre A, López-Macías C, Marafioti T, Mehta H, Partridge A, Kanzig C, Rivellese F, Galson JD et al.
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LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation
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Rivellese F, Humby F, Kelly S, Rocher V, Pitzalis C
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SYNOVIAL MAST CELLS CORRELATE WITH INFLAMMATION AND CELLULAR INFILTRATION AND ARE ASSOCIATED WITH ECTOPIC LYMPHOID STRUCTURES IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS
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Synovial Mast Cells Associate with High Disease Activity and Predict Radiographic Progression at 12 Months in Patients with Early Rheumatoid Arthritis
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Suurmond J, Rivellese F, Dorjée AL, Bakker AM, Rombouts YJPC, Rispens T, Wolbink G, Zaldumbide A et al.
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Toll-like receptor triggering augments activation of human mast cells by anti-citrullinated protein antibodies
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Rivellese F, Suurmond J, Habets K, Dorjée AL, Ramamoorthi N, Townsend MJ, de Paulis A, Marone G et al.
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Ability of Interleukin‐33– and Immune Complex–Triggered Activation of Human Mast Cells to Down‐Regulate Monocyte‐Mediated Immune Responses
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THU0024 Human Mast Cells Stimulated with IL-33 and Immune Complexes Down-Regulate Monocyte Activation in Rheumatoid Arthritis
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Annals of the Rheumatic Diseases
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IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation
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European Journal of Immunology
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Rivellese F, Suurmond J, de Paulis A, Marone G, Huizinga TWJ, Toes REM
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IgE and IL-33-mediated triggering of human basophils inhibits TLR4-induced monocyte activation
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Eur J Immunol
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Toll-like receptor triggering augments activation of human mast cells by anti-citrullinated protein antibodies
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Annals of the Rheumatic Diseases
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Activation of human basophils by combined toll-like receptor- and FcεRI-triggering can promote Th2 skewing of naive T helper cells
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FRI0035 Expression and functions of vascular endothelial growth factor and angiopoietin receptors in human synovial mast cells
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Human basophils modulate monocyte activation
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Macrophagic activation syndrome in adult-onset Still's disease: report of a complex case
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Helicobacter pylori HP(2-20) induces eosinophil activation and accumulation in superficial gastric mucosa and stimulates VEGF-α and TGF-β release by interacting with formyl-peptide receptors
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Drug hypersensitivity reactions. Part II. Extra-cutaneous manifestations
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Heart failure in Churg-Strauss Syndrome: a case responsive to high-dose intravenous immunoglobulins therapy
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