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Research

Publications: Miss Suzanne Eldridge

Thorup AS, Dell’Accio F, Eldridge SE ( 2023 ) . A Mouse Model of Acute Cartilage Injury and Repair . vol. 2598 , 337 - 344 .
Eldridge S, Barawi A, Thorup AS, Fernandez BF, Bharde S, Sikandar S, Guan Z, Kaneva M et al. ( 2022 ) . AB0156 INTRA-ARTICULAR AGRIN PROVIDES DIRECT PAIN RELIEF IN OSTEOARTHRITIS AND CARTILAGE DEFECTS . Annals of the Rheumatic Diseases vol. 81 , ( Suppl 1 ) 1208.1 - 121208 .
THORUP A, Caxaria S, Dell'Accio F, Thomas BL, Suleman Y, Nalesso G, Luyten FP, Dell'Accio F et al. ( 2022 ) . In vivo potency assay for the screening of bioactive molecules on cartilage formation . Lab Animal
Nalesso G, Thorup AS, Eldridge SE, De Palma A, Kaur A, Peddireddi K, Blighe K, Rana S et al. ( 2021 ) . Calcium calmodulin kinase II activity is required for cartilage homeostasis in osteoarthritis . Scientific Reports vol. 11 , ( 1 )
Eldridge S, Barawi A, Wang H, Roelofs A, Kaneva M, Guan Z, Lydon H, Thomas B et al. ( 2021 ) . AB0039 AGRIN REPAIRS BONE AND CARTILAGE IN VIVO . Annals of the Rheumatic Diseases vol. 80 , ( Suppl 1 ) 1052.1 - 101052 .
Thorup AS, Strachan D, Caxaria S, Poulet B, Thomas B, Eldridge S, Nalesso G, Whiteford J et al. ( 2021 ) . OP0200 BLOCKING ROR2 IMPROVES CARTILAGE INTEGRITY AND PROVIDES PAIN RELIEF IN OSTEOARTHRITIS . Annals of the Rheumatic Diseases vol. 80 , ( Suppl 1 ) 120.1 - 12121 .
Thomas B, Eldridge S, Nosrati B, Alvarez M, THORUP A-S, Nalesso G, Caxaria S, Barawi A et al. ( 2021 ) . WNT3A-loaded exosomes enable cartilage repair . Journal of Extracellular Vesicles
Thorup AS, Dell'Accio F, Eldridge SE ( 2021 ) . Lessons from joint development for cartilage repair in the clinic . Developmental Dynamics vol. 250 , ( 3 ) 360 - 376 .
Thorup A-S, Strachan D, Caxaria S, Poulet B, Thomas B, Eldridge S, Nalesso G, Whiteford J et al. ( 2020 ) . ROR2 blockade as a therapy for osteoarthritis . Science Translational Medicine vol. 12 , ( 561 )
Eldridge SE, Barawi A, Wang H, Roelofs AJ, Kaneva M, GUAN Z, Lydon H, Thomas B et al. ( 2020 ) . Agrin induces long term osteochondral regeneration by supporting repair morphogenesis . Science Translational Medicine vol. 12 , ( 559 )
Pengas I, Eldridge S, Assiotis A, McNicholas M, Mendes JE, Laver L ( 2018 ) . MMP-3 in the peripheral serum as a biomarker of knee osteoarthritis, 40 years after open total knee meniscectomy . J Exp Orthop vol. 5 , ( 1 )
Thorup A-S, Eldridge SE, Caxaria S, Nalesso G, Thomas BL, Pitzalis C, Luyten F, Dell'Accio F ( 2017 ) . A Potency Assay for Assessing the Chondrogenic Efficiency of Bioactive Molecules in Human Cartilage in vivo . Osteoarthritis and Cartilage . vol. 25 ,
Eldridge SE, Thomas BL, Shanmuganathan K, Strachan D, Ali A, Thorup A-S, Caxaria S, Nalesso G et al. ( 2017 ) . Agrin inhibits canonical WNT signalling through LRP4 . Osteoarthritis and Cartilage . vol. 25 ,
Thomas BL, Nalesso G, Eldridge SE, Pitzalis C, Dell'accio F ( 2017 ) . WNT16 is up-regulated in the joint following inflammation . Osteoarthritis and Cartilage . vol. 25 ,
Eldridge S, Nalesso G, Ismail H, Vicente-Greco K, Kabouridis P, Ramachandran M, Niemeier A, Herz J et al. ( 2016 ) . Agrin mediates chondrocyte homeostasis and requires both LRP4 and α-dystroglycan to enhance cartilage formation in vitro and in vivo . Annals of the Rheumatic Diseases vol. 75 , ( 6 ) 1228 - 1235 .
nalesso, thomas, sherwood JC, Yu J, Addimanda O, Eldridge SE, Thorup, Dale L et al. ( 2016 ) . WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis . Annals of Rheumatic Diseases
Eldridge SE, Petrycki E, Pitzalis C, Whiteford J, Dell'Accio F ( 2016 ) . MMP3 cleaves agrin in cartilage and reduces its chondrogenic potency . Osteoarthritis and Cartilage . vol. 24 ,
Nalesso G, Wagner K, Bertrand J, Sherwood JC, Thomas BL, Eldridge SE, Pitzalis C, Dell'Accio F ( 2016 ) . Pharmacological Blockade of CAMKII is Detrimental for Osteoarthritis Progression . Osteoarthritis and Cartilage . Conference: 2016 OARSI World Congress on Osteoarthritis vol. 24 (Suppl 1) , S149 - S149 .
Eldridge S, Vicente-Greco K, Nalesso G, Pitzalis C, Perretti M, Kabouridis P, Dell'Accio F ( 2014 ) . Agrin expression is downregulated in OA and is required for chondrocyte differentiation . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 95 , A8 - A9 .
Sherwood JC, Bertrand J, Eldridge SE, Dell'accio F ( 2014 ) . Cellular and molecular mechanisms of cartilage damage and repair . Drug Discovery Today vol. 19 , ( 8 ) 1172 - 1177 .
Eldridge S, Vicent-Greco K, Nalesso G, Pitzalis C, Perretti M, Kabouridis P, Dell'Accio F ( 2013 ) . Agrin expression is downregulated in OA and is required for chondrocyte differentiation . Osteoarthritis and Cartilage vol. 21 , s112 - s113 .
Nalesso G, Thomas BL, Eldridge SE, Wagner K, Sherwood J, Bertrand J, Pap T, Pitzalis C et al. ( 2013 ) . Wnt5a/CaMKII pathway is activated in osteoarthritis and promotes loss of chondrocyte phenotype . Osteoarthritis and Cartilage . vol. 21 ,