Skip to main content
Research

Publications: Dr Sabarinath Vallath

Kolluri KK, Alifrangis C, Kumar N, Ishii Y, Price S, Michaut M, Williams S, Barthorpe S et al. ( 2018 ) . Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells . Elife vol. 7 ,
Whilding LM, Parente-Pereira AC, Zabinski T, Davies DM, Petrovic RMG, Kao YV, Saxena SA, Romain A et al. ( 2017 ) . Targeting of Aberrant αvβ6 Integrin Expression in Solid Tumors Using Chimeric Antigen Receptor-Engineered T Cells . Molecular Therapy vol. 25 , ( 1 ) 259 - 273 .
Whilding LM, Vallath S, Maher J ( 2016 ) . The integrin αvβ6: a novel target for CAR T-cell immunotherapy? . Biochem Soc Trans vol. 44 , ( 2 ) 349 - 355 .
Vallath S, Sage EK, Kolluri KK, Lourenco SN, Teixeira VS, Chimalapati S, George PJ, Janes SM et al. ( 2016 ) . CADM1 inhibits squamous cell carcinoma progression by reducing STAT3 activity . Sci Rep vol. 6 ,
Vallath S, Hynds RE, Succony L, Janes SM, Giangreco A ( 2014 ) . Targeting EGFR signalling in chronic lung disease: therapeutic challenges and opportunities . Eur Respir J vol. 44 , ( 2 ) 513 - 522 .
Moore KM, Thomas GJ, Duffy SW, Warwick J, Gabe R, Chou P, Ellis IO, Green AR et al. ( 2014 ) . Therapeutic targeting of integrin αvβ6 in breast cancer . Journal of the National Cancer Institute vol. 106 , ( 8 )
Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA et al. ( 2013 ) . Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence . Clin Cancer Res vol. 20 , ( 2 ) 344 - 357 .
Coughlan L, Vallath S, Gros A, Giménez-Alejandre M, Van Rooijen N, Thomas GJ, Baker AH, Cascalló M et al. ( 2012 ) . Combined fiber modifications both to target α(v)β(6) and detarget the coxsackievirus-adenovirus receptor improve virus toxicity profiles in vivo but fail to improve antitumoral efficacy relative to adenovirus serotype 5 . Hum Gene Ther vol. 23 , ( 9 ) 960 - 979 .
Allen MD, Vaziri R, Green M, Chelala C, Brentnall AR, Dreger S, Vallath S, Nitch-Smith H et al. ( 2011 ) . Clinical and functional significance of α9β1 integrin expression in breast cancer: A novel cell-surface marker of the basal phenotype that promotes tumour cell invasion . Journal of Pathology vol. 223 , ( 5 ) 646 - 658 .
Marsh D, Suchak K, Moutasim KA, Vallath S, Hopper C, Jerjes W, Upile T, Kalavrezos N et al. ( 2011 ) . Stromal features are predictive of disease mortality in oral cancer patients . Journal of Pathology vol. 223 , ( 4 ) 470 - 481 .
Marsh D, Suchak K, Moutasim KA, Vallath S, Hopper C, Jerjes W, Upile T, Kalavrezos N et al. ( 2011 ) . Stromal features are predictive of disease mortality in oral cancer patients . J Pathol vol. 223 , ( 4 ) 470 - 481 .
Filipović A, Gronau JH, Green AR, Wang J, Vallath S, Shao D, Rasul S, Ellis IO et al. ( 2011 ) . Biological and clinical implications of nicastrin expression in invasive breast cancer . Breast Cancer Research and Treatment vol. 125 , ( 1 ) 43 - 53 .
Marsh D, Suchak K, Moutasim K, Vallath S, Hopper C, Jerjes W, Upile T, Kalavrezos N et al. ( 2011 ) . Stromal features are predictive of disease mortality in oral cancer patients . J Pathol vol. 4 , ( 223 ) 470 - 481 .
Wagstaff JL, Vallath S, Marshall JF, Williamson RA, Howard MJ ( 2010 ) . Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein-peptide interactions . Chemical Communications vol. 46 , ( 40 ) 7533 - 7535 .
Saha A, Ellison D, Thomas GJ, Vallath S, Mather SJ, Hart IR, Marshall JF ( 2010 ) . High-resolution in vivo imaging of breast cancer by targeting the pro-invasive integrin αvβ6 . Journal of Pathology vol. 222 , ( 1 ) 52 - 63 .
Coughlan L, Vallath S, Saha A, Flak M, McNeish IA, Vassaux G, Marshall JF, Hart IR et al. ( 2009 ) . In vivo retargeting of adenovirus type 5 to αvβ6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery . Journal of Virology vol. 83 , ( 13 ) 6416 - 6428 .