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Research

Publications: Dr Eve Hornsby

Gadhok R, Hornsby E, Kok KB, Lindsay JO, Stagg AJ ( 2024 ) . P120 A novel population of classical monocytes is expanded in CD and defined by an upregulation of genes relating to mononuclear cell differentiation and response to microbes . Journal of Crohn's and Colitis vol. 18 , ( Supplement_1 ) i410 - i410 .
Gordon H, Wichmann K, Lewis A, Sanders T, Wildemann M, Hoti I, Hornsby E, Kok KB et al. ( 2023 ) . Human Intestinal Dendritic Cells Can Overcome Retinoic Acid Signaling to Generate Proinflammatory CD4 T Cells with Both Gut and Skin Homing Properties . The Journal of Immunology vol. 212 , ( 1 ) 96 - 106 .
Hornsby E, Gadhok R, Yadon AN, Lindsay JO, Stagg AJ ( 2023 ) . DOP04 Single cell RNA sequencing reveals a potential role for IFNγ in priming circulating monocytes for intestinal inflammatory function in Crohn’s Disease . Journal of Crohn's and Colitis vol. 17 , ( Supplement_1 ) i61 - i62 .
Hornsby E, Gadhok R, Yadon AN, Lindsay JO, Stagg AJ ( 2023 ) . Single cell RNA sequencing reveals a potential role for IFNγ in priming circulating monocytes for intestinal inflammatory function in Crohn's Disease . JOURNAL OF CROHNS & COLITIS . vol. 17 , I61 - I62 .
Hornsby E, King HW, Peiris M, Buccafusca R, Lee W-YJ, Wing ES, Blackshaw LA, Lindsay JO et al. ( 2022 ) . The cation channel TRPM8 influences the differentiation and function of human monocytes . Journal of Leukocyte Biology vol. 112 , ( 3 ) 365 - 381 .
Gordon H, Rodger B, Hornsby E, McGuire J, Kok KB, Lindsay JO, Stagg AJ ( 2022 ) . P039 The role of α4β7+CLA+ ‘dual tropic’ T cells in inflammatory bowel disease . Journal of Crohn's and Colitis vol. 16 , ( Supplement_1 ) i156 - i156 .
Gordon H, Rodger B, Hornsby E, McGuire J, Kok KB, Lindsay JO, Stagg AJ ( 2022 ) . The role of α4β7+CLA+ 'dual tropic' T cells in inflammatory bowel disease . JOURNAL OF CROHNS & COLITIS . vol. 16 , I156 - I156 .
Hornsby E, Yadon AN, Clarke A, Grant E, Lindsay JO, Stagg AJ ( 2021 ) . P068 The combination of JAK1 and TPL2 or IRAK4 inhibitors is more effective than single agents in reducing TLR-mediated cytokine responses in human monocyte populations . Journal of Crohn's and Colitis vol. 15 , ( Supplement_1 ) s173 - s173 .
Gordon H, Hoti I, Wichmann K, Saunders T, Wildemann M, Hornsby E, McCarthy NE, Lindsay JO et al. ( 2021 ) . P105 Dendritic cells imprint pro-inflammatory α4β7+CLA+ T cells with potential for gut and skin homing . Gut . Conference: Posters vol. 70 , a95 - a96 .
Stagg AJ, Hornsby E, Knight SC ( 2020 ) . Antigen‐Presenting Cells . Encyclopedia of Life Sciences , vol. 1 , Wiley
Hawrylowicz C, Hornsby E, Cheadle C, Pfeffer P, Laranjo N, Cruikshank W, Tuzova M, Litonjua AA et al. ( 2019 ) . Vitamin D in pregnancy and offspring immunology . Bone Abstracts
Hornsby E, Peiris M, Peiris M, King HW, Wing ES, Lindsay JO, Blackshaw LA, Stagg AJ ( 2019 ) . P016 Constitutive activity of the cation channel TRPM8 regulates monocyte to macrophage transition in humans to control intestinal inflammation . Journal of Crohn's and Colitis . vol. 13 , s094 - s094 .
Hornsby E, Pfeffer PE, Laranjo N, Cruikshank W, Tuzova M, Litonjua AA, Weiss ST, Carey VJ et al. ( 2017 ) . Vitamin D supplementation during pregnancy: Effect on the neonatal immune system in a randomized controlled trial . Journal of Allergy and Clinical Immunology vol. 141 , ( 1 ) 269 - 278.e1 .
Scott F, Kouassi M-A, Warnes G, Hornsby E, Elahi S, Adedibe M, Goralczyk A, Mannur K et al. ( 2017 ) . Isolation of human gastric interstitial cells of Cajal . NEUROGASTROENTEROLOGY AND MOTILITY . vol. 29 , 127 - 127 .
Pfeffer PE, Mann EH, Hornsby E, Chambers ES, Chen Y-H, Rice L, Hawrylowicz CM ( 2014 ) . Vitamin D Influences Asthmatic Pathology through Its Action on Diverse Immunological Pathways . Annals of the American Thoracic Society vol. 11 , ( Supplement 5 ) s314 - s321 .