Skip to main content
Research

Publications: Dr Weini Huang

Hoare JI, Hockings H, Saxena J, Silva VL, Haughey MJ, Wood GE, Nicolini F, Mirza H et al. ( 2022 ) . A novel cell line panel reveals non-genetic mediators of platinum resistance and phenotypic diversity in high grade serous ovarian cancer . Gynecologic Oncology vol. 167 , ( 1 ) 96 - 106 .
Lange JT, Rose JC, Chen CY, Pichugin Y, Xie L, Tang J, Hung KL, Yost KE et al. ( 2022 ) . The evolutionary dynamics of extrachromosomal DNA in human cancers . Nature Genetics vol. 54 , ( 10 ) 1527 - 1533 .
Hockings H, Lockley M, Graham T, Lakatos E, Huang W ( 2022 ) . Abstract PR015: Developing adaptive therapy to suppress the evolution of treatment resistance in high-grade serous ovarian cancer . Cancer Research vol. 82 , ( 10_Supplement ) pr015 - pr015 .
Evans JA, Carlotti E, Lin ML, Hackett RJ, Haughey MJ, Passman AM, Dunn L, Elia G et al. ( 2022 ) . Clonal Transitions and Phenotypic Evolution in Barrett's Esophagus . Gastroenterology vol. 162 , ( 4 ) 1197 - 1209.e13 .
Haughey M, Bassolas A, Sousa S, Baker A-M, Graham T, Nicosia V, Huang W ( 2022 ) . First passage time analysis of spatial mutation patterns reveals evolutionary dynamics of pre-existing resistance in colorectal cancer .
Lakatos E, Hockings H, Mossner M, Huang W, Lockley M, Graham TA ( 2021 ) . LiquidCNA: Tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations . iScience vol. 24 , ( 8 )
Lakatos E, Hockings H, Mossner M, Huang W, Lockley M, Lockley M, Graham T ( 2021 ) . LiquidCNA: tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations .
Passman A, Haughey M, Carlotti E, Williams M, Cereser B, Lin M, Devkumar S, Gabrield J et al. ( 2021 ) . Clonal dynamics of normal hepatocyte expansions in homeostatic human livers and their association with the biliary epithelium .
Werner B, Case J, Williams MJ, Chkhaidze K, Temko D, Fernández-Mateos J, Cresswell GD, Nichol D et al. ( 2020 ) . Measuring single cell divisions in human tissues from multi-region sequencing data . Nature Communications vol. 11 , ( 1 )
Hoare JI, Hockings H, Saxena J, Silva VL, Maniati E, Mirza HB, Huang W, Wood GE et al. ( 2020 ) . Platinum resistance induces diverse evolutionary trajectories in high grade serous ovarian cancer .
Passman AM, Haughey MJ, Carlotti E, Williams M, Cereser B, Russo FP, Hoare M, Kocher H et al. ( 2020 ) . 450 CLONAL DYNAMICS AND CELL-OF-ORIGIN OF NORMAL HEPATOCYTE EXPANSIONS IN HOMEOSTATIC HUMAN LIVERS AND THEIR ASSOCIATION WITH THE BILIARY EPITHELIUM . Gastroenterology vol. 158 , ( 6 ) s - 1276 .
Passman AM, Haughey MJ, Carlotti E, Williams M, Cereser B, Russo FP, Hoare M, Kocher H et al. ( 2020 ) . CLONAL DYNAMICS AND CELL-OF-ORIGIN OF NORMAL HEPATOCYTE EXPANSIONS IN HOMEOSTATIC HUMAN LIVERS AND THEIR ASSOCIATION WITH THE BILIARY EPITHELIUM . GASTROENTEROLOGY . Conference: AACR vol. 158 , S1276 - S1276 .
Pichugin Y, Huang W, Werner B ( 2019 ) . Stochastic dynamics of extra-chromosomal DNA .
Retel C, Kowallik V, Huang W, Werner B, Becks L, Feulner P, Huang W ( 2019 ) . The feedback between selection and demography shapes genomic diversity during coevolution . Science Advances
Chkhaidze K, Heide T, Werner B, Williams MJ, Huang W, Caravagna G, Baker A-M, Graham TA et al. ( 2019 ) . Abstract 4232: Spatially constrained tumor growth affects the patterns of clonal selection and neutral drift in cancer genomic data . Conference: Bioinformatics, Convergence Science, and Systems Biology4232 - 4232 .
Chkhaidze K, Heide T, Werner B, Williams MJ, Huang W, Caravagna G, Graham TA, Sottoriva A ( 2019 ) . Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data . PLoS Computational Biology vol. 15 , ( 7 )
Werner B, Case J, Williams M, Chkhaidze K, Temko D, Fernandez-Mateos J, Cresswell G, Nichol D et al. ( 2019 ) . Measuring single cell divisions in human cancers from multi-region sequencing data .
Chkhaidze K, Heide T, Werner B, Williams M, Huang W, Caravagna G, Graham T, Sottoriva A ( 2019 ) . Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data .
Park HJ, Pichugin Y, Huang W, Traulsen A ( 2019 ) . Population size changes and extinction risk of populations driven by mutant interactors . Phys Rev E vol. 99 , ( 2-1 ) 022305 - 022305 .
Boddy AM, Huang W, Aktipis A ( 2018 ) . Life History Trade-Offs in Tumors . Curr Pathobiol Rep vol. 6 , ( 4 ) 201 - 207 .
Baker A-M, Huang W, Wang X-MM, Jansen M, Ma X-J, Domingo E, Wright NA, Rodriguez-Justo M et al. ( 2018 ) . In Situ Mutation Detection Maps the Clonal Architecture of Colorectal Cancer and Adenomas . JOURNAL OF PATHOLOGY . vol. 245 , S10 - S10 .
Huang W, Traulsen A, Werner B, Hiltunen T, Becks L ( 2017 ) . Dynamical trade-offs arise from antagonistic coevolution and decrease intraspecific diversity . Nat Commun vol. 8 , ( 1 ) 2059 - 2059 .
Baker A-M, Huang W, Wang X-MM, Jansen M, Ma X-J, Kim J, Anderson CM, Wu X et al. ( 2017 ) . Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution . Nat Commun vol. 8 , ( 1 ) 1998 - 1998 .
Baker A-M, Wang M, Ma X-J, Anderson C, Huang W, Domingo E, Lewis A, Bridgewater J et al. ( 2017 ) . Abstract 3953: Visualization of treatment resistant subclones in colorectal cancer by mutation specific RNA in situ hybridization . Cancer Research . vol. 77 , 3953 - 3953 .
Amado A, Fernández L, Huang W, Ferreira FF, Campos PRA ( 2016 ) . Competing metabolic strategies in a multilevel selection model . Royal Society Open Science vol. 3 , ( 11 ) 160544 - 160544 .
Huang W, de Araujo Campos PR, Moraes de Oliveira V, Fagundes Ferrreira F ( 2016 ) . A resource-based game theoretical approach for the paradox of the plankton . PeerJ vol. 4 , e2329 - e2329 .
Huang W, Hauert C, Traulsen A ( 2015 ) . Stochastic game dynamics under demographic fluctuations . Proc Natl Acad Sci U S A vol. 112 , ( 29 ) 9064 - 9069 .
Amado A, Huang W, Campos PRA, Ferreira FF ( 2015 ) . Learning process in public goods games . Physica A Statistical Mechanics and its Applications vol. 430 , 21 - 31 .
Huang W, Werner B, Traulsen A ( 2012 ) . The impact of random frequency-dependent mutations on the average population fitness . BMC Evolutionary Biology vol. 12 , ( 1 )