Publications: Dr Loic Rolas
Sánchez-López A, Espinós-Estévez C, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Fanjul V, Riquelme-Borja R, Hamczyk MR et al.
(
2021
)
.
Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome
.
Circulation
vol.
144
,
(
22
)
1777
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1794
.
Reglero-Real N, Pérez-Gutiérrez L, Yoshimura A, Rolas L, Garrido-Mesa J, Barkaway A, Pickworth C, Saleeb RS et al.
(
2021
)
.
Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation
.
Immunity
vol.
54
,
(
9
)
1989
-
2004.e9
.
Marcos-Ramiro B, Gil-Ordóñez A, Marín-Ramos NI, Ortega-Nogales FJ, Balabasquer M, Gonzalo P, Khiar-Fernández N, Rolas L et al.
(
2021
)
.
Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome
.
ACS Central Science
vol.
7
,
(
8
)
1300
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1310
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Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen-Woods C, Reglero-Real N, Stein M et al.
(
2021
)
.
Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage
.
Immunity
vol.
54
,
(
7
)
1494
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1510.e7
.
Dang PMC, Rolas L, El-Benna J
(
2020
)
.
The Dual Role of Reactive Oxygen Species-Generating Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Gastrointestinal Inflammation and Therapeutic Perspectives
.
Antioxidants and Redox Signaling
vol.
33
,
(
5
)
354
-
373
.
Madjene LC, Danelli L, Dahdah A, Vibhushan S, Bex-Coudrat J, Pacreau E, Vaugier C, Claver J et al.
(
2020
)
.
Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment
.
Kidney International
vol.
97
,
(
3
)
516
-
527
.
Owen-Woods C, Joulia R, Barkaway A, Rolas L, Ma B, Nottebaum FA, Arkill KP, Stein M et al.
(
2020
)
.
Local microvascular leakage promotes trafficking of activated neutrophils to remote organs
.
Journal of Clinical Investigation
Arabi-Derkawi R, O’Dowd Y, Cheng N, Rolas L, Boussetta T, Raad H, Marzaioli V, Pintard C et al.
(
2019
)
.
The kinesin light chain–related protein PAT1 promotes superoxide anion production in human phagocytes
.
Journal of Immunology
vol.
202
,
(
5
)
1549
-
1558
.
Reglero-Real N, Rolas L, Nourshargh S
(
2019
)
.
Leukocyte Trafficking: Time to Take Time Seriously
.
Immunity
vol.
50
,
(
2
)
273
-
275
.
NOURSHARGH S, ROLAS L, BARKAWAY A
(
2019
)
.
Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome
.
Nature Medicine423
-
426
.
GIRBL T, Lenn T, Perez L, ROLAS L, BARKAWAY A, Thiriot A, del Fresno C, Lynam E et al.
(
2018
)
.
Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the atypical receptor ACKR1 determine discrete stages of neutrophil diapedesis
.
Immunity
Belambri SA, Rolas L, Raad H, Hurtado-Nedelec M, Dang PMC, El-Benna J
(
2018
)
.
NADPH oxidase activation in neutrophils: Role of the phosphorylation of its subunits
.
European Journal of Clinical Investigation
vol.
48
,
Rolas L, Boussif A, Weiss E, Lettéron P, Haddad O, El-Benna J, Rautou PE, Moreau R et al.
(
2018
)
.
NADPH oxidase depletion in neutrophils from patients with cirrhosis and restoration via toll-like receptor 7/8 activation
.
Gut
vol.
67
,
(
8
)
1505
-
1516
.
Boussif A, Rolas L, Weiss E, Bouriche H, Moreau R, Périanin A
(
2016
)
.
Impaired intracellular signaling, myeloperoxidase release and bactericidal activity of neutrophils from patients with alcoholic cirrhosis
.
Journal of Hepatology
vol.
64
,
(
5
)
1041
-
1048
.
Rolas L, Makhezer N, Hadjoudj S, El-Benna J, Djerdjouri B, Elkrief L, Moreau R, Périanin A
(
2013
)
.
Inhibition of mammalian target of rapamycin aggravates the respiratory burst defect of neutrophils from decompensated patients with cirrhosis
.
Hepatology
vol.
57
,
(
3
)
1163
-
1171
.