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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Loic Rolas

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Sánchez-López A, Espinós-Estévez C, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Fanjul V, Riquelme-Borja R, Hamczyk MR et al. ( 2021 ) . Cardiovascular Progerin Suppression and Lamin A Restoration Rescue Hutchinson-Gilford Progeria Syndrome . Circulation vol. 144 , ( 22 ) 1777 - 1794 .
Reglero-Real N, Pérez-Gutiérrez L, Yoshimura A, Rolas L, Garrido-Mesa J, Barkaway A, Pickworth C, Saleeb RS et al. ( 2021 ) . Autophagy modulates endothelial junctions to restrain neutrophil diapedesis during inflammation . Immunity vol. 54 , ( 9 ) 1989 - 2004.e9 .
Marcos-Ramiro B, Gil-Ordóñez A, Marín-Ramos NI, Ortega-Nogales FJ, Balabasquer M, Gonzalo P, Khiar-Fernández N, Rolas L et al. ( 2021 ) . Isoprenylcysteine Carboxylmethyltransferase-Based Therapy for Hutchinson-Gilford Progeria Syndrome . ACS Central Science vol. 7 , ( 8 ) 1300 - 1310 .
Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen-Woods C, Reglero-Real N, Stein M et al. ( 2021 ) . Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage . Immunity vol. 54 , ( 7 ) 1494 - 1510.e7 .
Dang PMC, Rolas L, El-Benna J ( 2020 ) . The Dual Role of Reactive Oxygen Species-Generating Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Gastrointestinal Inflammation and Therapeutic Perspectives . Antioxidants and Redox Signaling vol. 33 , ( 5 ) 354 - 373 .
Madjene LC, Danelli L, Dahdah A, Vibhushan S, Bex-Coudrat J, Pacreau E, Vaugier C, Claver J et al. ( 2020 ) . Mast cell chymase protects against acute ischemic kidney injury by limiting neutrophil hyperactivation and recruitment . Kidney International vol. 97 , ( 3 ) 516 - 527 .
Owen-Woods C, Joulia R, Barkaway A, Rolas L, Ma B, Nottebaum FA, Arkill KP, Stein M et al. ( 2020 ) . Local microvascular leakage promotes trafficking of activated neutrophils to remote organs . Journal of Clinical Investigation
Arabi-Derkawi R, O’Dowd Y, Cheng N, Rolas L, Boussetta T, Raad H, Marzaioli V, Pintard C et al. ( 2019 ) . The kinesin light chain–related protein PAT1 promotes superoxide anion production in human phagocytes . Journal of Immunology vol. 202 , ( 5 ) 1549 - 1558 .
Reglero-Real N, Rolas L, Nourshargh S ( 2019 ) . Leukocyte Trafficking: Time to Take Time Seriously . Immunity vol. 50 , ( 2 ) 273 - 275 .
NOURSHARGH S, ROLAS L, BARKAWAY A ( 2019 ) . Development of a CRISPR/Cas9-based therapy for Hutchinson-Gilford progeria syndrome . Nature Medicine423 - 426 .
GIRBL T, Lenn T, Perez L, ROLAS L, BARKAWAY A, Thiriot A, del Fresno C, Lynam E et al. ( 2018 ) . Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the atypical receptor ACKR1 determine discrete stages of neutrophil diapedesis . Immunity
Belambri SA, Rolas L, Raad H, Hurtado-Nedelec M, Dang PMC, El-Benna J ( 2018 ) . NADPH oxidase activation in neutrophils: Role of the phosphorylation of its subunits . European Journal of Clinical Investigation vol. 48 ,
Rolas L, Boussif A, Weiss E, Lettéron P, Haddad O, El-Benna J, Rautou PE, Moreau R et al. ( 2018 ) . NADPH oxidase depletion in neutrophils from patients with cirrhosis and restoration via toll-like receptor 7/8 activation . Gut vol. 67 , ( 8 ) 1505 - 1516 .
Boussif A, Rolas L, Weiss E, Bouriche H, Moreau R, Périanin A ( 2016 ) . Impaired intracellular signaling, myeloperoxidase release and bactericidal activity of neutrophils from patients with alcoholic cirrhosis . Journal of Hepatology vol. 64 , ( 5 ) 1041 - 1048 .
Rolas L, Makhezer N, Hadjoudj S, El-Benna J, Djerdjouri B, Elkrief L, Moreau R, Périanin A ( 2013 ) . Inhibition of mammalian target of rapamycin aggravates the respiratory burst defect of neutrophils from decompensated patients with cirrhosis . Hepatology vol. 57 , ( 3 ) 1163 - 1171 .
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