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  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Vidya Darbari

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Corsini P, Wang S, Rehman S, Fenn K, Sagar A, Sirovica S, Cleaver L, Edwards-Gayle C et al. ( 2022 ) . Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation . Access Microbiology vol. 4 , ( 5 )
Corsini PM, Wang S, Rehman S, Fenn K, Sagar A, Sirovica S, Cleaver L, Edwards-Gayle CJC et al. ( 2022 ) . Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation . npj Biofilms and Microbiomes vol. 8 , ( 1 )
Darbari VC, Ciccone J, Patel JS, Islam B, Agarwal PK, Haider S ( 2020 ) . Electrostatic Switching Controls Channel Dynamics of the Sensor Protein VirB10 in A. tumefaciens Type IV Secretion System . ACS Omega Article acsomega.9b03313 ,
Fenn K, Wong CT, Darbari VC ( 2020 ) . Mycobacterium tuberculosis Uses Mce Proteins to Interfere With Host Cell Signaling . Frontiers in Molecular Biosciences vol. 6 ,
Glyde R, Fuzhou Y, DARBARI VC, Zhang N, Buck M, Zhang X ( 2017 ) . Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation . Molecular Cell
Zhang N, Darbari VC, Glyde R, Zhang X, Buck M ( 2016 ) . The bacterial enhancer-dependent RNA polymerase . Biochem J vol. 473 , ( 21 ) 3741 - 3753 .
Sawicka M, Wanrooij PH, Darbari VC, Tannous E, Hailemariam S, Bose D, Makarova AV, Burgers PM et al. ( 2016 ) . The dimeric architecture of checkpoint Mec1ATR and Tel1ATM reveal a common structural organization . Journal of Biological Chemistry
Chandran Darbari V, Waksman G ( 2015 ) . Structural biology of bacterial type IV secretion systems . Annual Reviews
Yang Y, Darbari VC, Zhang N, Lu D, Glyde R, Wang Y-P, Winkelman JT, Gourse RL et al. ( 2015 ) . Structures of the RNA polymerase-σ54 reveal new and conserved regulatory strategies . Science vol. 349 , Article 6250 , 882 - 885 .
Darbari VC, Lawton E, Lu D, Burrows PC, Wiesler S, Joly N, Zhang N, Zhang X et al. ( 2014 ) . Molecular basis of nucleotide-dependent substrate engagement and remodeling by an AAA+ activator . Nucleic Acids Research vol. 42 , ( 14 ) 9249 - 9261 .
Rivera-Calzada A, Fronzes R, Savva CG, Chandran V, Lian PW, Laeremans T, Pardon E, Steyaert J et al. ( 2013 ) . Structure of a bacterial type IV secretion core complex at subnanometre resolution . The EMBO journal vol. 32 , Article 8 , 1195 - 1204 .
Chandran V ( 2013 ) . Type IV secretion machinery: molecular architecture and function . Biochemical Society Transactions vol. 41 , Article 1 , 17 - 28 .
Banta LM, Kerr JE, Cascales E, Giuliano ME, Bailey ME, McKay C, Chandran V, Waksman G et al. ( 2011 ) . An Agrobacterium VirB10 mutation conferring a type IV secretion system gating defect . Journal of bacteriology vol. 193 , Article 10 , 2566 - 2574 .
Nurmohamed S, Vincent HA, Titman CM, Chandran V, Pears MR, Du D, Griffin JL, Callaghan AJ et al. ( 2011 ) . Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli . Journal of Biological Chemistry vol. 286 , Article 16 , 14315 - 14323 .
Rêgo AT, Chandran V, Waksman G ( 2010 ) . Two-step and one-step secretion mechanisms in Gram-negative bacteria: contrasting the type IV secretion system and the chaperone-usher pathway of pilus biogenesis . Biochemical Journal vol. 425 , Article 3 , 475 - 488 .
Meng G, Fronzes R, Chandran V, Remaut H, Waksman G ( 2009 ) . Protein oligomerization in the bacterial outer membrane (Review) . Molecular membrane biology vol. 26 , Article 3 , 136 - 145 .
Durand E, Verger D, Rêgo AT, Chandran V, Meng G, Fronzes R, Waksman G ( 2009 ) . Structural biology of bacterial secretion systems in Gram-negative pathogens-potential for new drug targets . Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious Disorders) vol. 9 , Article 5 , 518 - 547 .
Chandran V, Fronzes R, Duquerroy S, Cronin N, Navaza J, Waksman G ( 2009 ) . Structure of the outer membrane complex of a type IV secretion system . Nature vol. 462 , Article 7276 , 1011 - 1015 .
Chandran V, Poljak L, Vanzo NF, Leroy A, Miguel RNN, Fernandez-Recio J, Parkinson J, Burns C et al. ( 2007 ) . Recognition and cooperation between the ATP-dependent RNA helicase RhlB and ribonuclease RNase E . Journal of molecular biology vol. 367 , Article 1 , 113 - 132 .
Chandran V, Luisi BF ( 2006 ) . Recognition of enolase in the Escherichia coli RNA degradosome . Journal of molecular biology vol. 358 , Article 1 , 8 - 15 .
Chandran V ( 2006 ) . Structural and functional characterisation of the protein-protein and protein-RNA interactions in the RNA degradosome .
Chandran V, Stollar EJ, Lindorff-Larsen K, Harper JF, Chazin WJ, Dobson CM, Luisi BF, Christodoulou J ( 2006 ) . Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition . Journal of molecular biology vol. 357 , Article 2 , 400 - 410 .
Marcaida MJ, DePristo MA, Chandran V, Carpousis AJ, Luisi BF ( 2006 ) . The RNA degradosome: life in the fast lane of adaptive molecular evolution . Trends in biochemical sciences vol. 31 , Article 7 , 359 - 365 .
Chandran V, Callaghan A, Long J, Zaid O, Aurikka J, Ilag L, Robinson C, Carpousis AJ et al. ( 2004 ) . Protein-protein interactions in the RNA degradosome . PROTEIN SCIENCE . vol. 13 , 144 - 144 .
Dasgupta S, Chandran V, Bhinge A, Sewlikar S, Nimbkar A, Datta D ( 2004 ) . Role of L-lysine HCl in adoptive immune therapy towards development of suitable tuberculosis vaccination . Indian journal of experimental biology vol. 42 , Article 8 , 758 - 765 .
Callaghan AJ, Aurikko JP, Ilag LL, Grossmann JG, Chandran V, Kühnel K, Poljak L, Carpousis AJ et al. ( 2004 ) . Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E . Journal of molecular biology vol. 340 , Article 5 , 965 - 979 .
Calladine CR, Pratap V, Chandran V, Mizuguchi K, Luisi BF ( 2003 ) . Cylindrical channels from concave helices . Science vol. 299 , Article 5607 , 661 - 662 .
Dasgupta S, Bhinge A, Chandran V, Sewlikar S, Nimbkar A, Datta D ( 2003 ) . Role of L-lysine HCl in immunopotentiation towards development of suitable tuberculosis vaccination . Vaccine vol. 21 , Article 32 , 4722 - 4727 .
Datta D, Bhinge A, Chandran V ( 2001 ) . Lysine: Is it worth more? . Cytotechnology vol. 36 , Article 1-3 , 3 - 32 .
Datta D, Kundu PK, Biswas S, Dasgupta S, Bhinge A, Chandran V ( 2000 ) . Effect of cationic amino acid, l-lysine and its polymers on the growth and secretion of hybridoma cell line OKT-3 . Hybridoma vol. 19 , Article 4 , 339 - 346 .
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