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Research

Publications: Dr Nadeem Shaikh

Shaikh N, Mazzagatti A, De Angelis S, Johnson SC, Bakker B, Spierings DCJ, Wardenaar R, Maniati E et al. ( 2022 ) . Replication stress generates distinctive landscapes of DNA copy number alterations and chromosome scale losses . Genome Biology vol. 23 , ( 1 )
Shaikh N, McClelland SE ( 2021 ) . Diversity in chromosome numbers promotes resistance to chemotherapeutics . Developmental Cell vol. 56 , ( 17 ) 2399 - 2400 .
Mcclelland S, Tamura N, Shaikh N, Muliaditan D, Soliman T, McGuinness J, Maniati E, Moralli D et al. ( 2020 ) . Specific mechanisms of chromosomal instability indicate therapeutic sensitivities in high-grade serous ovarian carcinoma . Cancer Research
Tamura N, Shaikh N, Muliaditan D, McGuinness J, Moralli D, Durin MA, Green CM, Bowtell D et al. ( 2019 ) . Mechanisms of Chromosomal Instability in High-grade Serous Ovarian Carcinoma .
Worrall JT, Tamura N, Mazzagatti A, Shaikh N, van Lingen T, Bakker B, Spierings DCJ, Vladimirou E et al. ( 2018 ) . Non-random Mis-segregation of Human Chromosomes . Cell Reports vol. 23 , ( 11 ) 3366 - 3380 .
Zaaijer S, Shaikh N, Nageshan RK, Cooper JP ( 2016 ) . Rif1 Regulates the Fate of DNA Entanglements during Mitosis . Cell Reports vol. 16 , ( 1 ) 148 - 160 .
Tamura N, Shaikh N, McGuinness JR, Bowtell D, Balkwill F, Petermann E, McClelland SE ( 2016 ) . What drives chromosomal instability in high-grade serous ovarian cancer? . MOLECULAR BIOLOGY OF THE CELL . vol. 27 ,
Burrell RA, McClelland SE, Endesfelder D, Groth P, Weller MC, Shaikh N, Domingo E, Kanu N et al. ( 2013 ) . Replication stress links structural and numerical cancer chromosomal instability . Nature vol. 494 , ( 7438 ) 492 - 496 .