Publications: Dr Jianmin Chen

Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Montalvo Moreira SA, Rathod K, Chen J et al. ( 2022 ) . 20-hydroxyeicosatetraenoic acid (20-HETE) is a pivotal endogenous ligand for TRPV1-mediated neurogenic inflammation in the skin . British Journal of Pharmacology vol. 179 , ( 7 ) 1450 - 1469 .

Costa VV, Sugimoto MA, Hubner J, Bonilha CS, Queiroz-Junior CM, Gonçalves-Pereira MH, Chen J, Gobbetti T et al. ( 2022 ) . Targeting the Annexin A1-FPR2/ALX pathway for host-directed therapy in dengue disease . eLife vol. 11 ,

Chen J, Norling LV, Mesa JG, de Paula Silva M, Burton SE, Reutelingsperger C, Perretti M, Cooper D ( 2021 ) . Annexin A1 attenuates cardiac diastolic dysfunction in mice with inflammatory arthritis . Proceedings of the National Academy of Sciences of the United States of America vol. 118 , ( 38 )

De Gaetano M, Tighe C, Gahan K, Zanetti A, Chen J, Newson J, Cacace A, Marai M et al. ( 2021 ) . Asymmetric Synthesis and Biological Screening of Quinoxaline-Containing Synthetic Lipoxin A<inf>4</inf>Mimetics (QNX-sLXms) . Journal of Medicinal Chemistry vol. 64 , ( 13 ) 9193 - 9216 .

Chen J, Purvis GSD, Collotta D, Zoubi SA, Sugimoto MA, Cacace A, Martin L, Colas RA et al. ( 2020 ) . RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance . Frontiers in Immunology vol. 11 , 2080 - 2080 .

de Gaetano M, Butler E, Gahan K, Zanetti A, Marai M, Chen J, Cacace A, Hams E et al. ( 2019 ) . Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A<inf>4</inf> mimetics (sLXms) . European Journal of Medicinal Chemistry vol. 162 , 80 - 108 .

Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J et al. ( 2018 ) . Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis . FASEB Jfj201701303R - fj201701303R .

Khan AI, Kapoor A, Chen J, Martin L, Rogazzo M, Mercier T, Decosterd L, Collino M et al. ( 2018 ) . The Antimalarial Drug Artesunate Attenuates Cardiac Injury in A Rodent Model of Myocardial Infarction . Shock vol. 49 , ( 6 ) 675 - 681 .

Purvis GSD, Chiazza F, Chen J, Loiola RA, Martin L, Fountoulakis N, Gnudi L, Collino M et al. ( 2017 ) . Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes . Diabetologia

Johnson FL, Patel NSA, Purvis GSD, Chiazza F, Chen J, Sordi R, Hache G, Merezhko VV et al. ( 2017 ) . Inhibition of IκB Kinase at 24 Hours After Acute Kidney Injury Improves Recovery of Renal Function and Attenuates Fibrosis . J Am Heart Assoc vol. 6 , ( 7 )

Martin L, Gombert A, Chen J, Liebens J, Verleger J, Kalder J, Marx G, Jacobs M et al. ( 2017 ) . The β-d-Endoglucuronidase Heparanase Is a Danger Molecule That Drives Systemic Inflammation and Correlates with Clinical Course after Open and Endovascular Thoracoabdominal Aortic Aneurysm Repair: Lessons Learnt from Mice and Men . Front Immunol vol. 8 , 681 - 681 .

Martin L, Chen J, Zechendorf E, Chiazza F, Oggero S, Collino M, Marx G, Schuerholz T et al. ( 2017 ) . ROLE OF THE beta-D-ENDOGLUCURONIDASE HEPARANASE IN SEPTIC CARDIOMYOPATHY . SHOCK . Conference: European Shock Society vol. 47 , 129 - 129 .

Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A ( 2016 ) . ACTIVATION OF TRPV1 BY 12(S)-HPETE AND 20-HETE RELEASES CGRP AND PROTECTS THE HEART AGAINST THE CARDIAC DYSFUNCTION CAUSED BY LPS . SHOCK . Conference: Exp Biology 2016 vol. 46 , 31 - 32 .

Martin LB, Zechendorf E, Chen J, Brandenburg K, Marx G, Thiemermann C, Schuerholz T ( 2016 ) . THE SYNTHETIC ANTIMICROBIAL PEPTIDE 19-2.5 ATTENUATES SEPTIC CARDIOMYOPATHY IN A MURINE MODEL OF POLYMICROBIAL SEPSIS . SHOCK . Conference: Japanese Shock Society vol. 46 , 31 - 31 .

Chen J, Thiemermann C ( 2016 ) . Selenium and niacin for sepsis therapy: The sum is greater than its parts . Critical Care Medicine vol. 44 , ( 6 ) 1256 - 1257 .

Chen J, Kieswich J, Chiazza F, Moyes A, Gobbetti T, Purvis G, Salvatori D, Patel N et al. ( 2016 ) . IkB Kinase Inhibitor Attenuates Sepsis-Induced Cardiac Dysfunction in CKD . Journal of the American Society of Nephrology

Chen J, Hamers AJP, Finsterbusch M, Thiemermann C, Ahluwalia A ( 2016 ) . Activation of TRPV1 by 12(s)-HpETE and 20-HETE Releases CGRP and Protects the Heart Against the Cardiac Dysfunction Caused by LPS . FASEB JOURNAL . Conference: Exp Biology (FASEB) 2016 vol. 30 ,

Chen J, Kieswich J, Chiazza F, Gobbetti T, Patel NSA, Perretti M, Collino M, Yaqoob MM et al. ( 2015 ) . THE CARDIAC DYSFUNCTION CAUSED BY SEPSIS IN ANIMALS WITH CHRONIC KIDNEY DISEASE IS ATTENUATED BY INHIBITING I kappa B KINASE . SHOCK . vol. 44 , 16 - 16 .

Chen J, Kieswich J, Chiazza F, Gobbetti T, Patel NS, Perretti M, Collino M, Yaqoob MM et al. ( 2015 ) . THE CARDIAC DYSFUNCTION CAUSED BY SEPSIS IN ANIMALS WITH CHRONIC KIDNEY DISEASE IS ATTENUATED BY INHIBITING I kappa B KINASE . SHOCK . vol. 43 , 92 - 93 .

Gobbetti T, Coldewey SM, Chen J, McArthur S, Le Faouder P, Cenac N, Flower RJ, Thiemermann C et al. ( 2014 ) . Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis . Proceedings of the National Academy of Sciences of the United States of America vol. 111 , ( 52 ) 18685 - 18690 .

Chen J, Chiazza F, Collino M, Patel NSA, Coldewey SM, Thiemermann C ( 2014 ) . Gender dimorphism of the cardiac dysfunction in murine sepsis: Signalling mechanisms and age-dependency . PLoS ONE vol. 9 , ( 6 )

Chen J, Chiazza F, Collino M, Coldewey SM, Patel NS, Thiemermann C ( 2014 ) . GENDER DIMORPHISM OF THE CARDIAC DYSFUNCTION IN SEPSIS . SHOCK . vol. 41 , 35 - 35 .

Chen J, Kieswich J, Yaqoob MM, Thiemermann C ( 2014 ) . PRE-EXISTING CHRONIC KIDNEY DISEASE WORSENS MYOCARDIAL DYSFUNCTION CAUSED BY SEPSIS IN MICE . SHOCK . vol. 41 , 40 - 41 .

Hafner S, Wepler M, McCook O, Scheuerle A, Wagner F, Matallo J, Chen J, Calzia E et al. ( 2013 ) . EFFECTS OF THE PPAR-beta/delta AGONIST GW0742 ON RENAL INFLAMMATION AND KIDNEY TISSUE INJURY DURING RESUSCITATED PORCINE SEPTIC SHOCK . SHOCK . vol. 40 , 24 - 24 .