Publications: Dr Stephane Bourgeois

Hawe JS, Wilson R, Schmid KT, Zhou L, Lakshmanan LN, Lehne BC, Kühnel B, Scott WR et al. ( 2022 ) . Genetic variation influencing DNA methylation provides insights into molecular mechanisms regulating genomic function . Nature Genetics vol. 54 , ( 1 ) 18 - 29 .

Bourgeois S, Carr DF, Musumba CO, Penrose A, Esume C, Morris AP, Jorgensen AL, Zhang JE et al. ( 2021 ) . Genome-Wide association between EYA1 and Aspirin-induced peptic ulceration . EBioMedicine vol. 74 ,

Kanoni S, Kumar S, Amerikanou C, Kurth MJ, Stathopoulou MG, Bourgeois S, Masson C, Kannt A et al. ( 2021 ) . Nutrigenetic Interactions Might Modulate the Antioxidant and Anti-Inflammatory Status in Mastiha-Supplemented Patients With NAFLD . Frontiers in Immunology vol. 12 ,

Katsareli EA, Amerikanou C, Rouskas K, Dimopoulos A, Diamantis T, Alexandrou A, Griniatsos J, Bourgeois S et al. ( 2020 ) . A Genetic Risk Score for the Estimation of Weight Loss After Bariatric Surgery . Obesity Surgery vol. 30 , ( 4 ) 1482 - 1490 .

Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, Ciccacci C, Carcas AJ et al. ( 2019 ) . Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single‐Patient Data Meta‐Analysis in More Than 15,000 Individuals . Clinical Pharmacology & Therapeutics vol. 105 , ( 6 ) 1477 - 1491 .

Gottlieb A, Daneshjou R, DeGorter M, Bourgeois S, Svensson PJ, Wadelius M, Deloukas P, Montgomery SB et al. ( 2017 ) . Cohort-specific imputation of gene expression improves prediction of warfarin dose for African Americans . Genome Medicine vol. 9 , ( 1 )

Zhang JE, Klein K, Jorgensen AL, Francis B, Alfirevic A, Bourgeois S, Deloukas P, Zanger UM et al. ( 2017 ) . Effect of Genetic Variability in the CYP4F2, CYP4F11, and CYP4F12 Genes on Liver mRNA Levels and Warfarin Response . Front Pharmacol vol. 8 , 323 - 323 .

Carr DF, Bourgeois S, Chaponda M, Takeshita LY, Morris AP, Castro EMC, Alfirevic A, Jones AR et al. ( 2017 ) . Genome-wide association study of nevirapine hypersensitivity in a sub-Saharan African HIV-infected population . Journal of Antimicrobial Chemotherapy

Bourgeois S, Jorgensen A, Zhang EJ, Hanson A, Gillman MS, Bumpstead S, Toh CH, Williamson P et al. ( 2016 ) . A multi-factorial analysis of response to warfarin in a UK prospective cohort . Genome Medicine vol. 8 , ( 1 )

De T, Nwanze N, Hernandez W, Smithberger E, Tuck M, O'Brien T, Kittles R, Duarte J et al. ( 2016 ) . GENOME-WIDE ASSOCIATION STUDY TO IDENTIFY THE GENETIC DETERMINANTS OF WARFARIN INDUCED HEMORRHAGIC COMPLICATIONS IN AFRICAN AMERICANS (AAS) . CLINICAL PHARMACOLOGY & THERAPEUTICS . vol. 99 , S13 - S13 .

Parra EJ, Botton MR, Perini JA, Krithika S, Bourgeois S, Johnson TA, Tsunoda T, Pirmohamed M et al. ( 2015 ) . Genome-wide association study of warfarin maintenance dose in a Brazilian sample . Pharmacogenomics vol. 16 , ( 11 ) 1253 - 1263 .

Nwanze N, Hernandez W, Tuck M, O'Brien T, Kittles R, Duarte J, Bourgeois S, Cavallari L et al. ( 2015 ) . GENOME-WIDE ASSOCIATION STUDY TO IDENTIFY SUSCEPTIBILITY LOCI ASSOCIATED WITH HEMORRHAGIC COMPLICATIONS AMONG AFRICAN AMERICAN PATIENTS ON STABLE WARFARIN DOSE . CLINICAL PHARMACOLOGY & THERAPEUTICS . vol. 97 , S66 - S66 .

Carr D, Bourgeois S, Chaponda M, Castro EC, Deloukas P, Pirmohamed M ( 2014 ) . Genome‐wide association study of nevirapine hypersensitivity in a malawian HIV‐infected population . Clinical and Translational Allergy vol. 4 , ( Suppl 3 ) p125 - p125 .

Perera MA, Cavallari LH, Limdi NA, Gamazon ER, Konkashbaev A, Daneshjou R, Pluzhnikov A, Crawford DC et al. ( 2013 ) . Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study . The Lancet vol. 382 , ( 9894 ) 790 - 796 .

Daneshjou R, Tatonetti NP, Karczewski KJ, Sagreiya H, Bourgeois S, Drozda K, Burmester JK, Tsunoda T et al. ( 2013 ) . Pathway analysis of genome-wide data improves warfarin dose prediction . BMC Genomics vol. 14 , ( Suppl 3 )

Pérez-Andreu V, Teruel R, Corral J, Roldán V, García-Barberá N, Salloum-Asfar S, Gómez-Lechón MJ, Bourgeois S et al. ( 2012 ) . miR-133a Regulates Vitamin K 2,3-Epoxide Reductase Complex Subunit 1 (VKORC1), a Key Protein in the Vitamin K Cycle . Molecular Medicine vol. 18 , ( 11 ) 1466 - 1472 .

McCormack M, Alfirevic A, Bourgeois S, Farrell JJ, Kasperavičiūtė D, Carrington M, Sills GJ, Marson T et al. ( 2011 ) . HLA-A*3101 and Carbamazepine-Induced Hypersensitivity Reactions in Europeans . New England Journal of Medicine vol. 364 , ( 12 ) 1134 - 1143 .

Yotova V, Lefebvre J-F, Moreau C, Gbeha E, Hovhannesyan K, Bourgeois S, Bédarida S, Azevedo L et al. ( 2011 ) . An X-Linked Haplotype of Neandertal Origin Is Present Among All Non-African Populations . Molecular Biology and Evolution vol. 28 , ( 7 ) 1957 - 1962 .

Alfirevic A, Bourgeois S, Jorgensen A, Steen K, Weetman D, Park BK, Deloukas P, Pirmohamed M ( 2010 ) . Carbamazepine-induced hypersensitivity in Caucasians and genetic variability in the major histocompatibility complex . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 70 , 298 - 298 .

Bourgeois S, Yotova V, Wang S, Bourtoumieu S, Moreau C, Michalski R, Moisan J, Hill K et al. ( 2009 ) . X‐chromosome lineages and the settlement of the Americas . American Journal of Biological Anthropology vol. 140 , ( 3 ) 417 - 428 .

Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, Soranzo N, Whittaker P, Ranganath V et al. ( 2009 ) . A Genome-Wide Association Study Confirms VKORC1, CYP2C9, and CYP4F2 as Principal Genetic Determinants of Warfarin Dose . PLOS Genetics vol. 5 , ( 3 )

Bedoya G, Montoya P, García J, Soto I, Bourgeois S, Carvajal L, Labuda D, Alvarez V et al. ( 2006 ) . Admixture dynamics in Hispanics: A shift in the nuclear genetic ancestry of a South American population isolate . Proceedings of the National Academy of Sciences of the United States of America vol. 103 , ( 19 ) 7234 - 7239 .

Yotova V, Labuda D, Zietkiewicz E, Gehl D, Lovell A, Lefebvre J-F, Bourgeois S, Lemieux-Blanchard É et al. ( 2005 ) . Anatomy of a founder effect: myotonic dystrophy in Northeastern Quebec . Human Genetics vol. 117 , ( 2-3 ) 177 - 187 .

Lovell A, Moreau C, Yotova V, Xiao F, Bourgeois S, Gehl D, Bertranpetit J, Schurr E et al. ( 2005 ) . Ethiopia: between Sub-Saharan Africa and western Eurasia . Annals of Human Genetics vol. 69 , ( Pt 3 ) 275 - 287 .

LABUDA D, Krajinovic M, BOURGEOIS S ( 2005 ) . Allele specific oligonucleotide hybridization (ASO) . Encyclopaedia of Diagnostic Genomics and Proteomics, volume 2. , CRC PressI Llc

Bourgeois S, Labuda D ( 2004 ) . Dynamic allele-specific oligonucleotide hybridization on solid support . Analytical Biochemistry vol. 324 , ( 2 ) 309 - 311 .

Xiao F-X, Yotova V, Zietkiewicz E, Lovell A, Gehl D, Bourgeois S, Moreau C, Spanaki C et al. ( 2003 ) . Human X-chromosomal lineages in Europe reveal Middle Eastern and Asiatic contacts . European Journal of Human Genetics vol. 12 , ( 4 ) 301 - 311 .