Publications: Ms Eleanor Tyler

Tyler EJ, Pearce OMT ( 2024 ) . Tumor's Digest: Macrophage Metabolism Creates a Barrier to T Cells . Cancer Research vol. 84 , ( 20 ) 3322 - 3323 .

Lujan C, Tyler EJ, Ecker S, Webster AP, Stead ER, Martinez-Miguel VE, Milligan D, Garbe JC et al. ( 2024 ) . An expedited screening platform for the discovery of anti-ageing compounds in vitro and in vivo . Genome Medicine vol. 16 , ( 1 )

Carter EP, Yoneten KK, Gavara N, Tyler EJ, Gauthier V, Murray ER, Dijke PT, Cameron AJ et al. ( 2023 ) . Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function . The Journal of Pathology vol. 262 , ( 1 ) 90 - 104 .

Carter E, Yoneten K, Gavara N, Tyler E, Gauthier V, Murray E, Dijke PT, Cameron A et al. ( 2023 ) . Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function . Pancreatology vol. 23 , ( 4 ) e13 - e14 .

Puttock EH, Tyler EJ, Manni M, Maniati E, Butterworth C, Burger Ramos M, Peerani E, Hirani P et al. ( 2023 ) . Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis . Nature Communications vol. 14 , ( 1 )

Sarmin AM, Moussaid NE, Suntornnond R, Tyler EJ, Kim Y-H, Di Cio S, Megone WV, Pearce O et al. ( 2022 ) . Multi-Scale Analysis of the Composition, Structure, and Function of Decellularized Extracellular Matrix for Human Skin and Wound Healing Models . Biomolecules vol. 12 , ( 6 )

Wallis R, Milligan D, Hughes B, Mizen H, López-Domínguez JA, Eduputa U, Tyler EJ, Serrano M et al. ( 2022 ) . Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence . Aging vol. 14 , ( 10 ) 4220 - 4246 .

Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A et al. ( 2022 ) . Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion . Cell Reports vol. 38 , ( 4 )

Malacrida B, Nichols S, Maniati E, Jones R, Delanie-Smith R, Roozitalab R, Tyler EJ, Thomas M et al. ( 2021 ) . A human multi-cellular model shows how platelets drive production of diseased extracellular matrix and tissue invasion . iScience vol. 24 , ( 6 )

Wallis R, Josipovic N, Mizen H, Robles‐Tenorio A, Tyler EJ, Papantonis A, Bishop CL ( 2021 ) . Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence‐associated secretory phenotype . Journal of Extracellular Vesicles vol. 10 , ( 4 )

Tyler EJ, del Arroyo AG, Hughes BK, Wallis R, Garbe JC, Stampfer MR, Koh J, Lowe R et al. ( 2021 ) . Early growth response 2 (EGR2) is a novel regulator of the senescence programme . Aging Cell vol. 20 , ( 3 )

Milligan DA, Tyler EJ, Bishop CL ( 2020 ) . Tissue engineering to better understand senescence: Organotypics come of age . Mechanisms of Ageing and Development vol. 190 ,

Avelar RA, Ortega JG, Tacutu R, Tyler EJ, Bennett D, Binetti P, Budovsky A, Chatsirisupachai K et al. ( 2020 ) . A multidimensional systems biology analysis of cellular senescence in aging and disease . Genome Biology vol. 21 , ( 1 )

Ezcurra M, Benedetto A, Sornda T, Gilliat AF, Au C, Zhang Q, van Schelt S, Petrache AL et al. ( 2018 ) . C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies . Current Biology vol. 28 , ( 20 )

Ezcurra M, Benedetto A, Sornda T, Gilliat AF, Au C, Zhang Q, van Schelt S, Petrache AL et al. ( 2018 ) . C. elegans Eats Its Own Intestine to Make Yolk Leading to Multiple Senescent Pathologies . Current Biology vol. 28 , ( 16 ) 2544 - 2556.e5 .

Clarke RW, Novak P, Zhukov A, Tyler EJ, Cano-Jaimez M, Drews A, Richards O, Volynski K et al. ( 2016 ) . Low Stress Ion Conductance Microscopy of Sub-Cellular Stiffness . Soft Matter vol. 12 , ( 38 ) 7953 - 7958 .