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Research

Publications: Dr Florian Laforets

Joy J, Manchanda R, Balkwill F ( 2024 ) . Human 3D ovarian cancer models reveal 1 malignant cell intrinsic and extrinsic factors that 2 influence CAR T cell activity . Cancer Research
Malacrida B, Elorbany S, Maniati E, Laforets F, Manchanda R, Balkwill FR ( 2023 ) . Abstract 4551: Reconstructing the metastatic tumor microenvironment of high grade serous ovarian cancer: understanding the contribution of malignant cells . Cancer Research vol. 83 , ( 7_Supplement ) 4551 - 4551 .
Devlin M-J, Miller R, Laforets F, Kotantaki P, Garsed DW, Kristeleit R, Bowtell DD, McDermott J et al. ( 2022 ) . The tumour microenvironment of clear cell ovarian cancer . Cancer Immunology Research vol. 10 , ( 11 ) 1326 - 1339 .
Joy JD, Malacrida B, Laforêts F, Kotantaki P, Maniati E, Hopkins S, Calleja I, Brett S et al. ( 2022 ) . Abstract 693: TGFβ-mediated targeting of the extracellular matrix enhances the migration and cytotoxicity of CAR-T cells in 3D models of ovarian cancer . Cancer Research vol. 82 , ( 12_Supplement ) 693 - 693 .
Gopinathan G, Berlato C, Lakhani A, Szabova L, Pegrum C, Pedrosa A-R, Laforets F, Maniati E et al. ( 2022 ) . Immune mechanisms of resistance to cediranib in ovarian cancerDifferential response and resistance to cediranib in HGSOC . Molecular Cancer Therapeutics vol. 21 , ( 6 ) 1030 - 1043 .
Therizols G, Bash-Imam Z, Panthu B, Machon C, Vincent A, Ripoll J, Nait-Slimane S, Chalabi-Dchar M et al. ( 2022 ) . Alteration of ribosome function upon 5-fluorouracil treatment favors cancer cell drug-tolerance . Nature Communications vol. 13 , ( 1 )
Gopinathan G, Maniati E, Berlato C, Lakhani A, Pergum C, Laforets F, Szabova L, Balkwill F ( 2021 ) . Abstract 1094: Differential responses and mechanisms of resistance to cediranib in high grade serous ovarian cancer mouse models . Cancer Research . vol. 81 , 1094 - 1094 .
Devlin M-J, Kristeleit RS, McDermott J, Maniati E, Laforêts F, Kotantaki P, Miller R, Balkwill F ( 2021 ) . Abstract 2748: Impact of ARID1A mutation on the tumor microenvironment of advanced clear cell ovarian cancer . Cancer Research . vol. 81 , 2748 - 2748 .
Gopinathan G, Maniati E, Berlato C, Lakhani A, Pergum C, Laforets F, Szabova L, Balkwill F ( 2021 ) . Differential responses and mechanisms of resistance to cediranib in high grade serous ovarian cancer mouse models . CANCER RESEARCH . vol. 81 ,
Devlin M-J, Kristeleit RS, McDermott J, Maniati E, Laforets F, Kotantaki P, Miller R, Balkwill F ( 2021 ) . Impact of ARID1A mutation on the tumor microenvironment of advanced clear cell ovarian cancer . CANCER RESEARCH . vol. 81 ,
Erales J, Marchand V, Panthu B, Gillot S, Belin S, Ghayad SE, Garcia M, Laforêts F et al. ( 2017 ) . Evidence for rRNA 2′-O-methylation plasticity: Control of intrinsic translational capabilities of human ribosomes . Proceedings of the National Academy of Sciences of the United States of America vol. 114 , ( 49 ) 12934 - 12939 .
Bash-Imam Z, Thérizols G, Vincent A, Lafôrets F, Polay Espinoza M, Pion N, Macari F, Pannequin J et al. ( 2017 ) . Translational reprogramming of colorectal cancer cells induced by 5-fluorouracil through a miRNA-dependent mechanism . Oncotarget vol. 8 , ( 28 ) 46219 - 46233 .
Therizols G, Laforêts F, Marcel V, Catez F, Bouvet P, Diaz JJ ( 2015 ) . Ribosomal RNA Methylation and Cancer . Epigenetic Cancer Therapy ,
Therizols G, Laforêts F, Marcel V, Catez F, Bouvet P, Diaz J-J ( 2015 ) . Chapter 6 Ribosomal RNA Methylation and Cancer . Epigenetic Cancer Therapy , Elsevier