Publications: Dr Julia Ramirez Garcia

Orini M, van Duijvenboden S, Young WJ, Ramírez J, Jones AR, Tinker A, Munroe PB, Lambiase PD ( 2023 ) . Premature atrial and ventricular contractions detected on wearable-format electrocardiograms and prediction of cardiovascular events . European Heart Journal - Digital Health

van Duijvenboden S, Ramírez J, Young W, Olczak K, Ahmed F, Alhammadi MJAY, Bell C, Morris A et al. ( 2023 ) . Integration of genetic fine-mapping and multi-omics data reveals candidate effector genes for hypertension .

Young WJ, Lahrouchi N, Isaacs A, Duong TV, Foco L, Ahmed F, Brody JA, Salman R et al. ( 2022 ) . Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways . Nature Communications vol. 13 , ( 1 )

Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke SL, Bhatti KF et al. ( 2022 ) . Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis . Genome Biology vol. 23 , ( 1 )

Ramírez J, Van Duijvenboden S, Young WJ, Tinker A, Lambiase PD, Orini M, Munroe PB ( 2022 ) . Prediction of Coronary Artery Disease and Major Adverse Cardiovascular Events Using Clinical and Genetic Risk Scores for Cardiovascular Risk Factors . Circulation: Genomic and Precision Medicine vol. 15 , ( 5 ) 444 - 452 .

Ramírez J, Kiviniemi A, van Duijvenboden S, Tinker A, Lambiase PD, Junttila J, Perkiömäki JS, Huikuri HV et al. ( 2022 ) . ECG T-Wave Morphologic Variations Predict Ventricular Arrhythmic Risk in Low-and Moderate-Risk Populations . Journal of the American Heart Association vol. 11 , ( 17 )

Palmieri F, Gomis P, Ferreira D, Pueyo E, Martínez JP, Laguna P, Ramírez J ( 2022 ) . Weighted Time Warping Improves T-Wave Morphology Markers Clinical Significance . IEEE Transactions on Biomedical Engineering vol. 69 , ( 9 ) 2787 - 2796 .

Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL et al. ( 2022 ) . A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids . American Journal of Human Genetics vol. 109 , ( 8 ) 1366 - 1387 .

Ramírez J, Van Duijvenboden S, Young W, Tinker A, Lambiase P, Orini M, Munroe P ( 2022 ) . Prediction of coronary artery disease and major adverse cardiovascular events using clinical and genetic risk scores for cardiovascular risk factors . Atherosclerosis vol. 355 , 3 - 4 .

Naderi H, Ramírez J, Van Duijvenboden S, Aung N, Fung K, Young W, Petersen S, Munroe P ( 2022 ) . PREDICTING THE PATTERN OF ANATOMICAL LEFT VENTRICULAR HYPERTROPHY USING ELECTROPHYSIOLOGICAL BIOMARKERS FROM THE ECG QRS COMPLEX IN HYPERTENSIVE INDIVIDUALS FROM UK BIOBANK . Journal of hypertension . vol. 40 ,

Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen A et al. ( 2022 ) . A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse Ancestries .

Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU et al. ( 2022 ) . A saturated map of common genetic variants associated with human height . Nature

Graham SE, Clarke SL, Wu KHH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I et al. ( 2021 ) . The power of genetic diversity in genome-wide association studies of lipids . Nature vol. 600 , ( 7890 ) 675 - 679 .

Kanoni S, Graham S, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke S, Bhatti KF et al. ( 2021 ) . Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis .

Van Duijvenboden S, Ramírez J, Young WJ, Orini M, Mifsud B, Tinker A, Lambiase PD, Munroe PB ( 2021 ) . Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders . Human Molecular Genetics vol. 30 , ( 24 ) 2513 - 2523 .

Ramdas S, Judd J, Graham S, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke S et al. ( 2021 ) . A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids .

Palmieri F, Gomis P, Ferreira D, Ruiz JE, Bergasa B, Martín-Yebra A, Bukhari HA, Pueyo E et al. ( 2021 ) . Monitoring blood potassium concentration in hemodialysis patients by quantifying T-wave morphology dynamics . Scientific Reports vol. 11 , ( 1 )

Young W, Lahrouchi N, Isaacs A, Duong T, Foco L, Ahmed F, Brody J, Salman R et al. ( 2021 ) . Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization .

Fung K, Biasiolli L, Hann E, Lukaschuk E, Ramírez J, van Duijvenboden S, Aung N, Paiva JM et al. ( 2021 ) . 9 Identification of thirty novel loci for cardiovascular magnetic resonance derived aortic distensibility in the UK Biobank . Heart . Conference: BSCMR 2021 vol. 107 , a6 - a8 .

Tardajos Ayllón B, Basu J, Burrage M, Kotanidis CP, Ramirez J, Coyle C ( 2021 ) . The British Cardiovascular Society Young Investigator Award 2021 . Heart (British Cardiac Society) vol. 107 , ( 22 ) 1844 - 1845 .

Bukhari HA, Palmieri F, Ramirez J, Laguna P, Ruiz JE, Ferreira D, Potse M, Sanchez C et al. ( 2021 ) . Characterization of T Wave Amplitude, Duration and Morphology Changes during Hemodialysis: Relationship with Serum Electrolyte Levels and Heart Rate . IEEE Transactions on Biomedical Engineering vol. 68 , ( 8 ) 2467 - 2478 .

Palmieri F, Gomis P, Ruiz JE, Ferreira D, Martín-Yebra A, Pueyo E, Martínez JP, Ramírez J et al. ( 2021 ) . ECG-based monitoring of blood potassium concentration: Periodic versus principal component as lead transformation for biomarker robustness . Biomedical Signal Processing and Control vol. 68 ,

van Duijvenboden S, Ramirez J, Orini M, Tinker A, Munroe P, Lambiase P ( 2021 ) . 85 Prognostic value of premature ventricular complexes during exercise stress testing in 56,000 individuals without known structural heart disease from UK biobank: is a single ectopic prognostic? . Heart . Conference: Cardiac rhythm management vol. 107 , a68 - a68 .

Young W, Warren H, Mook-Kanamori D, Ramirez J, van Duijvenboden S, Orini M, Tinker A, van Heemst D et al. ( 2021 ) . BS8 Genetically-determined serum calcium levels influence markers of ventricular repolarisation: a mendelian randomisation study . Heart . Conference: Basic science vol. 107 , a159 - a160 .

Young WJ, Warren HR, Mook-Kanamori DO, Ramírez J, Van Duijvenboden S, Orini M, Tinker A, Van Heemst D et al. ( 2021 ) . Genetically Determined Serum Calcium Levels and Markers of Ventricular Repolarization: A Mendelian Randomization Study in the UK Biobank . Circulation: Genomic and Precision Medicine vol. 14 , ( 3 )

Rezaei MJ, Woodward JR, Ramírez J, Munroe P ( 2021 ) . A novel two-stage heart arrhythmia ensemble classifier . Computers vol. 10 , ( 5 )

Palmieri F, Gomis P, Ruiz JE, Ferreira D, Martín-Yebra A, Pueyo E, Martínez JP, Ramírez J et al. ( 2021 ) . Nonlinear t-wave time warping-based sensing model for non-invasive personalised blood potassium monitoring in hemodialysis patients: A pilot study . Sensors vol. 21 , ( 8 )

Mensah-Kane J, Schmidt AF, Hingorani AD, Finan C, Chen Y, van Duijvenboden S, Orini M, Lambiase PD et al. ( 2021 ) . No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis . Frontiers in Genetics vol. 12 ,

Ramírez J, van Duijvenboden S, Young WJ, Orini M, Jones AR, Lambiase PD, Munroe PB, Tinker A ( 2021 ) . Analysing electrocardiographic traits and predicting cardiac risk in UK biobank . JRSM Cardiovasc Dis vol. 10 ,

Rezaei MJ, Woodward JR, Ramirez J, Munroe P ( 2021 ) . Combination of Isolation Forest, SMOTE and Ensemble Learning for the classification of Atrial Fibrillation and Ventricular Arrhythmia . Proceedings of the International Conference on Biomedical Innovations and Applications, BIA 2021 . 45 - 50 .

Ramírez J, Tinker A ( 2021 ) . Ventricular Restitution Predicts Paroxysmal Atrial Fibrillation in Horses . Function vol. 2 , ( 1 )

Palmieri F, Gomis P, Ruiz JE, Ferreira D, Pueyo E, Martinez JP, Laguna P, Ramirez J ( 2021 ) . Weighted Time Warping T-Wave Analysis Robust to Delineation Errors: Clinical Implications . Computing in Cardiology . vol. 2021-September ,

Ntalla I, Weng LC, Cartwright JH, Hall AW, Sveinbjornsson G, Tucker NR, Choi SH, Chaffin MD et al. ( 2020 ) . Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction . Nature Communications vol. 11 , ( 1 )

Young WJ, van Duijvenboden S, Ramírez J, Jones A, Tinker A, Munroe PB, Lambiase PD, Orini M ( 2020 ) . A Method to Minimise the Impact of ECG Marker Inaccuracies on the Spatial QRS-T angle: Evaluation on 1,512 Manually Annotated ECGs . Biomedical Signal Processing and Control vol. 64 ,

Rezaei MJ, Woodward JR, Ramirez J, Munroe P ( 2020 ) . Data Augmentation for Heart Arrhythmia Classification . Proceedings - International Conference on Tools with Artificial Intelligence, ICTAI . vol. 2020-November , 929 - 934 .

García-González J, Ramírez J, Howard DM, Brennan CH, Munroe PB, Keers R ( 2020 ) . The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank . Translational Psychiatry vol. 10 , ( 1 )

Van Duijvenboden S, Ramirez J, Young WJ, Tinker A, Munroe PB, Lambiase PD, Orini M ( 2020 ) . Evaluating the Impact of Physiological Variability in Genome-Wide Association Studies of Resting Heart Rate . Computing in Cardiology . vol. 2020-September ,

Aung N, Young WJ, Van Duijvenboden S, Ramirez J, Petersen SE, Munroe PB ( 2020 ) . Genetic Architecture of Quantitative Cardiovascular Traits: Blood Pressure, ECG and Imaging Phenotypes . Computing in Cardiology . vol. 2020-September ,

Ramirez J, Van Duijvenboden S, Young WJ, Tinker A, Lambiase PD, Munroe PB, Orini M ( 2020 ) . Interaction between ECG and Genetic Markers of Coronary Artery Disease . Computing in Cardiology . Conference: CinC 2020 from: 13/09/2020 to: 16/09/2020 , vol. 2020-September ,

Palmieri F, Gomis P, Ruiz JE, Ferreira D, Martin-Yebra A, Pueyo E, Laguna P, Martinez JP et al. ( 2020 ) . Potassium Monitoring from Multilead T-wave Morphology Changes during Hemodyalisis: Periodic Versus Principal Component Analysis . Computing in Cardiology . vol. 2020-September ,

Ramirez J, Van Duijvenboden S, Tinker A, Lambiase PD, Munroe PB, Orini M ( 2020 ) . Sex Differences in the Morphology of RR-Matched T-waves . Computing in Cardiology . vol. 2020-September ,

Young WJ, Ramirez J, Van Duijvenboden S, Tinker A, Lambiase PD, Munroe PB, Orini M ( 2020 ) . Will Genetic Data Significantly Change Cardiovascular Risk Prediction in Daily Practice? . Computing in Cardiology . vol. 2020-September ,

Weng LC, Hall AW, Choi SH, Jurgens SJ, Haessler J, Bihlmeyer NA, Grarup N, Lin H et al. ( 2020 ) . Genetic determinants of electrocardiographic P-wave duration and relation to atrial fibrillation . Circulation: Genomic and Precision Medicine389 - 395 .

Van Duijvenboden S, Ramírez J, Young WJ, Mifsud B, Orini M, Tinker A, Munroe PB, Lambiase PD ( 2020 ) . Genetic Basis and Prognostic Value of Exercise QT Dynamics . Circulation: Genomic and Precision Medicine vol. 13 , ( 4 )

Ramírez J, van Duijvenboden S, Young WJ, Orini M, Lambiase PD, Munroe PB, Tinker A ( 2020 ) . Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval . American Journal of Human Genetics vol. 106 , ( 6 ) 764 - 778 .

Fung K, Biasiolli L, Hann E, Ramirez J, Lukaschuk E, Aung N, Paiva J, Werys K et al. ( 2020 ) . 3.2 First Genome-Wide Association Study of Cardiovascular Magnetic Resonance Derived Aortic Distensibility Reveals 7 Loci . Artery Research . vol. 25 ,

Palmieri F, Gomis P, Ferreira D, Ruiz JE, Bergasa B, Martin-Yebra A, Bukhari HA, Pueyo E et al. ( 2019 ) . T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients . 2016 Computing in Cardiology Conference (CinC) . Conference: 2019 Computing in Cardiology Conference (CinC) vol. 45 ,

Bukhari HA, Palmieri F, Ferreira D, Potse M, Ramirez J, Laguna P, Sanchez C, Pueyo E ( 2019 ) . Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels . 2016 Computing in Cardiology Conference (CinC) . Conference: 2019 Computing in Cardiology Conference (CinC) vol. 45 , 1 - 4 .

García-González J, Ramírez J, Howard D, Brennan C, Munroe P, Keers R ( 2019 ) . The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank .

Fung K, Ramírez J, Warren HR, Aung N, Lee AM, Tzanis E, Petersen SE, Munroe PB ( 2019 ) . Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants . Scientific Reports vol. 9 , ( 1 )

Munroe PB, Ramírez J, van Duijvenboden S ( 2019 ) . Resting Heart Rate and Type 2 Diabetes: A Complex Relationship in Need of Greater Understanding . Journal of the American College of Cardiology vol. 74 , ( 17 ) 2175 - 2177 .

Ramírez J, van Duijvenboden S, Aung N, Laguna P, Pueyo E, Tinker A, Lambiase PD, Orini M et al. ( 2019 ) . Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics . Circulation: Arrhythmia and Electrophysiology vol. 12 , ( 10 ) e007549 - e007549 .

Palmieri F, Ramírez J, Laguna P, Gomis P, Ferreira D, Ruiz JE, Bergasa B, Martín-Yebra A et al. ( 2019 ) . T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients . Computing in Cardiology . vol. 2019-September ,

Bukhari HA, Palmieri F, Ferreira D, Potse M, Ramírez J, Laguna P, Sánchez C, Pueyo E ( 2019 ) . Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels . Computing in Cardiology . vol. 2019-September ,

Ntalla I, Weng L-C, Cartwright J, Hall AW, Sveinbjornsson G, Tucker N, Choi SH, Chaffin M et al. ( 2019 ) . Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction .

Ramirez J, van Duijvenboden S, Tinker A, Lambiase P, Orini M, Munroe PB ( 2019 ) . 21 The cardiovascular predictive value and genetic basis of T-wave morphology . Heart . Conference: Cardiac rhythm management vol. 105 ,

van Duijvenboden S, Ramirez J, Orini M, Tinker A, Munroe PB, Lambiase P ( 2019 ) . 22 Cardiac repolarization during exercise reveals independent prognostic information for cardiovascular risk prediction . Heart . Conference: Cardiac Rhythm Management vol. 105 ,

Ramírez J, Duijvenboden SV, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A et al. ( 2018 ) . Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system . Nature Communications vol. 9 , ( 1 )

Ramirez J, Van Duijvenboden S, Laguna P, Pueyo E, Tinker A, Lambiase PD, Munroe PB, Orini M ( 2018 ) . Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology . Computing in Cardiology . Conference: Computing in Cardiology ( Maastricht, The Netherlands ) from: 23/09/2018 to: 26/09/2018 , vol. 2018-September ,

Palmieri F, Burattini L, Pablo Martinez J, Ramirez J ( 2018 ) . T-Wave Morphology Restitution in Chronic Heart Failure Patient with Atrial Fibrillation . Computing in Cardiology . vol. 2018-September ,

Prins BP, Mead TJ, Brody JA, Sveinbjornsson G, Ntalla I, Bihlmeyer NA, van den Berg M, Bork-Jensen J et al. ( 2018 ) . Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6 . Genome Biology vol. 19 , ( 1 )

Ramírez J, Orini M, Mincholé A, Monasterio V, Cygankiewicz I, Bayés de Luna A, Martínez JP, Laguna P et al. ( 2017 ) . Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model . PLoS ONE vol. 12 , ( 10 )

Ramirez J, Orini M, Tucker JD, Pueyo E, Laguna P ( 2017 ) . Variability of Ventricular Repolarization Dispersion Quantified by Time-Warping the Morphology of the T-Waves . IEEE Transactions on Biomedical Engineering vol. 64 , ( 7 ) 1619 - 1630 .

Ramírez J, Orini M, Mincholé A, Monasterio V, Cygankiewicz I, de Luna AB, Martínez JP, Pueyo E et al. ( 2017 ) . T-wave morphology restitution predicts sudden cardiac death in patients with chronic heart failure . Journal of the American Heart Association vol. 6 , ( 5 )

Ramírez J, Orini M, Pueyo E, Laguna P ( 2017 ) . Comparison of ECG T-wave Duration and morphology restitution markers for sudden cardiac death prediction in chronic heart Failure . Computing in Cardiology . vol. 44 , 1 - 4 .

Ramírez J, Orini M, Pueyo E, Laguna P ( 2017 ) . Quantification of t-wave morphological variability using time-warping methods . IFMBE Proceedings . vol. 65 , 478 - 481 .

Ramírez J, Orini M, Pueyo E, Laguna P ( 2017 ) . T-wave morphology restitution dependency with heart rate range and its association with sudden cardiac death in chronic heart failure . Computing in Cardiology . vol. 44 , 1 - 4 .

Ramirez J, Orini M, Derek Tucker J, Pueyo E, Laguna P ( 2016 ) . An index for T-wave pointwise amplitude variability quantification . Computing in Cardiology . vol. 43 , 49 - 52 .

Lenis G, Menges R, Ramirez J, Cygankiewicz I, De Luna AB, Martinez JP, Laguna P, Dossel O ( 2016 ) . Postextrasystolic T wave change to stratify risk of pump failure death in patients with chronic heart failure . Computing in Cardiology . vol. 43 , 33 - 36 .

Ramírez J, Monasterio V, Mincholé A, Llamedo M, Lenis G, Cygankiewicz I, Bayés De Luna A, Malik M et al. ( 2015 ) . Automatic SVM classification of sudden cardiac death and pump failure death from autonomic and repolarization ECG markers . Journal of Electrocardiology vol. 48 , ( 4 ) 551 - 557 .

Ramírez J, Laguna P, Bayés De Luna A, Malik M, Pueyo E ( 2015 ) . Erratum: QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death (Journal of Electrocardiology (2014) 47:6 (842-8)) . Journal of Electrocardiology vol. 48 , ( 1 ) 128 - 129 .

Ramírez J, Laguna P, Bayés De Luna A, Malik M, Pueyo E ( 2014 ) . QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death . Journal of Electrocardiology vol. 47 , ( 6 ) 842 - 848 .

Ramírez J, Cygankiewicz I, Laguna P, Malik M, Pueyo E ( 2014 ) . Circadian pattern and sex differences of QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure patients . Computing in Cardiology . vol. 41 , 173 - 176 .

Ramirez J, Minchole A, Bolea J, Laguna P, Pueyo E ( 2013 ) . Prediction of sudden cardiac death in chronic heart failure patients by analysis of restitution dispersion . Computing in Cardiology . vol. 40 , 1 - 4 .

Ramirez J, Minchole A, Laguna P, Pueyo E ( 2012 ) . Characterization of cardiac repolarization response to heart rate changes provoked by a tilt test . Computing in Cardiology . vol. 39 , 673 - 676 .