Publications: Dr Julia Ramirez Garcia
Orini M, van Duijvenboden S, Young WJ, Ramírez J, Jones AR, Tinker A, Munroe PB, Lambiase PD
(
2023
)
.
Premature atrial and ventricular contractions detected on wearable-format electrocardiograms and prediction of cardiovascular events
.
European Heart Journal - Digital Health
van Duijvenboden S, Ramírez J, Young W, Olczak K, Ahmed F, Alhammadi MJAY, Bell C, Morris A et al.
(
2023
)
.
Integration of genetic fine-mapping and multi-omics data reveals candidate effector genes for hypertension
.
Young WJ, Lahrouchi N, Isaacs A, Duong TV, Foco L, Ahmed F, Brody JA, Salman R et al.
(
2022
)
.
Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways
.
Nature Communications
vol.
13
,
(
1
)
Kanoni S, Graham SE, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke SL, Bhatti KF et al.
(
2022
)
.
Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
.
Genome Biology
vol.
23
,
(
1
)
Ramírez J, Van Duijvenboden S, Young WJ, Tinker A, Lambiase PD, Orini M, Munroe PB
(
2022
)
.
Prediction of Coronary Artery Disease and Major Adverse Cardiovascular Events Using Clinical and Genetic Risk Scores for Cardiovascular Risk Factors
.
Circulation: Genomic and Precision Medicine
vol.
15
,
(
5
)
444
-
452
.
Ramírez J, Kiviniemi A, van Duijvenboden S, Tinker A, Lambiase PD, Junttila J, Perkiömäki JS, Huikuri HV et al.
(
2022
)
.
ECG T-Wave Morphologic Variations Predict Ventricular Arrhythmic Risk in Low-and Moderate-Risk Populations
.
Journal of the American Heart Association
vol.
11
,
(
17
)
Palmieri F, Gomis P, Ferreira D, Pueyo E, Martínez JP, Laguna P, Ramírez J
(
2022
)
.
Weighted Time Warping Improves T-Wave Morphology Markers Clinical Significance
.
IEEE Transactions on Biomedical Engineering
vol.
69
,
(
9
)
2787
-
2796
.
Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL et al.
(
2022
)
.
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
.
American Journal of Human Genetics
vol.
109
,
(
8
)
1366
-
1387
.
Ramírez J, Van Duijvenboden S, Young W, Tinker A, Lambiase P, Orini M, Munroe P
(
2022
)
.
Prediction of coronary artery disease and major adverse cardiovascular events using clinical and genetic risk scores for cardiovascular risk factors
.
Atherosclerosis
vol.
355
,
3
-
4
.
Naderi H, Ramírez J, Van Duijvenboden S, Aung N, Fung K, Young W, Petersen S, Munroe P
(
2022
)
.
PREDICTING THE PATTERN OF ANATOMICAL LEFT VENTRICULAR HYPERTROPHY USING ELECTROPHYSIOLOGICAL BIOMARKERS FROM THE ECG QRS COMPLEX IN HYPERTENSIVE INDIVIDUALS FROM UK BIOBANK
.
Journal of hypertension
.
vol.
40
,
Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen A et al.
(
2022
)
.
A Saturated Map of Common Genetic Variants Associated with Human Height from 5.4 Million Individuals of Diverse Ancestries
.
Yengo L, Vedantam S, Marouli E, Sidorenko J, Bartell E, Sakaue S, Graff M, Eliasen AU et al.
(
2022
)
.
A saturated map of common genetic variants associated with human height
.
Nature
Graham SE, Clarke SL, Wu KHH, Kanoni S, Zajac GJM, Ramdas S, Surakka I, Ntalla I et al.
(
2021
)
.
The power of genetic diversity in genome-wide association studies of lipids
.
Nature
vol.
600
,
(
7890
)
675
-
679
.
Kanoni S, Graham S, Wang Y, Surakka I, Ramdas S, Zhu X, Clarke S, Bhatti KF et al.
(
2021
)
.
Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis
.
Van Duijvenboden S, Ramírez J, Young WJ, Orini M, Mifsud B, Tinker A, Lambiase PD, Munroe PB
(
2021
)
.
Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders
.
Human Molecular Genetics
vol.
30
,
(
24
)
2513
-
2523
.
Ramdas S, Judd J, Graham S, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke S et al.
(
2021
)
.
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
.
Palmieri F, Gomis P, Ferreira D, Ruiz JE, Bergasa B, Martín-Yebra A, Bukhari HA, Pueyo E et al.
(
2021
)
.
Monitoring blood potassium concentration in hemodialysis patients by quantifying T-wave morphology dynamics
.
Scientific Reports
vol.
11
,
(
1
)
Young W, Lahrouchi N, Isaacs A, Duong T, Foco L, Ahmed F, Brody J, Salman R et al.
(
2021
)
.
Genetic analyses of the QT interval and its components in over 250K individuals identifies new loci and pathways affecting ventricular depolarization and repolarization
.
Fung K, Biasiolli L, Hann E, Lukaschuk E, Ramírez J, van Duijvenboden S, Aung N, Paiva JM et al.
(
2021
)
.
9 Identification of thirty novel loci for cardiovascular magnetic resonance derived aortic distensibility in the UK Biobank
.
Heart
.
Conference:
BSCMR 2021
vol.
107
,
a6
-
a8
.
Tardajos Ayllón B, Basu J, Burrage M, Kotanidis CP, Ramirez J, Coyle C
(
2021
)
.
The British Cardiovascular Society Young Investigator Award 2021
.
Heart (British Cardiac Society)
vol.
107
,
(
22
)
1844
-
1845
.
Bukhari HA, Palmieri F, Ramirez J, Laguna P, Ruiz JE, Ferreira D, Potse M, Sanchez C et al.
(
2021
)
.
Characterization of T Wave Amplitude, Duration and Morphology Changes during Hemodialysis: Relationship with Serum Electrolyte Levels and Heart Rate
.
IEEE Transactions on Biomedical Engineering
vol.
68
,
(
8
)
2467
-
2478
.
Palmieri F, Gomis P, Ruiz JE, Ferreira D, Martín-Yebra A, Pueyo E, Martínez JP, Ramírez J et al.
(
2021
)
.
ECG-based monitoring of blood potassium concentration: Periodic versus principal component as lead transformation for biomarker robustness
.
Biomedical Signal Processing and Control
vol.
68
,
van Duijvenboden S, Ramirez J, Orini M, Tinker A, Munroe P, Lambiase P
(
2021
)
.
85 Prognostic value of premature ventricular complexes during exercise stress testing in 56,000 individuals without known structural heart disease from UK biobank: is a single ectopic prognostic?
.
Heart
.
Conference:
Cardiac rhythm management
vol.
107
,
a68
-
a68
.
Young W, Warren H, Mook-Kanamori D, Ramirez J, van Duijvenboden S, Orini M, Tinker A, van Heemst D et al.
(
2021
)
.
BS8 Genetically-determined serum calcium levels influence markers of ventricular repolarisation: a mendelian randomisation study
.
Heart
.
Conference:
Basic science
vol.
107
,
a159
-
a160
.
Young WJ, Warren HR, Mook-Kanamori DO, Ramírez J, Van Duijvenboden S, Orini M, Tinker A, Van Heemst D et al.
(
2021
)
.
Genetically Determined Serum Calcium Levels and Markers of Ventricular Repolarization: A Mendelian Randomization Study in the UK Biobank
.
Circulation: Genomic and Precision Medicine
vol.
14
,
(
3
)
Rezaei MJ, Woodward JR, Ramírez J, Munroe P
(
2021
)
.
A novel two-stage heart arrhythmia ensemble classifier
.
Computers
vol.
10
,
(
5
)
Palmieri F, Gomis P, Ruiz JE, Ferreira D, Martín-Yebra A, Pueyo E, Martínez JP, Ramírez J et al.
(
2021
)
.
Nonlinear t-wave time warping-based sensing model for non-invasive personalised blood potassium monitoring in hemodialysis patients: A pilot study
.
Sensors
vol.
21
,
(
8
)
Mensah-Kane J, Schmidt AF, Hingorani AD, Finan C, Chen Y, van Duijvenboden S, Orini M, Lambiase PD et al.
(
2021
)
.
No Clinically Relevant Effect of Heart Rate Increase and Heart Rate Recovery During Exercise on Cardiovascular Disease: A Mendelian Randomization Analysis
.
Frontiers in Genetics
vol.
12
,
Ramírez J, van Duijvenboden S, Young WJ, Orini M, Jones AR, Lambiase PD, Munroe PB, Tinker A
(
2021
)
.
Analysing electrocardiographic traits and predicting cardiac risk in UK biobank
.
JRSM Cardiovasc Dis
vol.
10
,
Rezaei MJ, Woodward JR, Ramirez J, Munroe P
(
2021
)
.
Combination of Isolation Forest, SMOTE and Ensemble Learning for the classification of Atrial Fibrillation and Ventricular Arrhythmia
.
Proceedings of the International Conference on Biomedical Innovations and Applications, BIA 2021
.
45
-
50
.
Ramírez J, Tinker A
(
2021
)
.
Ventricular Restitution Predicts Paroxysmal Atrial Fibrillation in Horses
.
Function
vol.
2
,
(
1
)
Palmieri F, Gomis P, Ruiz JE, Ferreira D, Pueyo E, Martinez JP, Laguna P, Ramirez J
(
2021
)
.
Weighted Time Warping T-Wave Analysis Robust to Delineation Errors: Clinical Implications
.
Computing in Cardiology
.
vol.
2021-September
,
Ntalla I, Weng LC, Cartwright JH, Hall AW, Sveinbjornsson G, Tucker NR, Choi SH, Chaffin MD et al.
(
2020
)
.
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
.
Nature Communications
vol.
11
,
(
1
)
Young WJ, van Duijvenboden S, Ramírez J, Jones A, Tinker A, Munroe PB, Lambiase PD, Orini M
(
2020
)
.
A Method to Minimise the Impact of ECG Marker Inaccuracies on the Spatial QRS-T angle: Evaluation on 1,512 Manually Annotated ECGs
.
Biomedical Signal Processing and Control
vol.
64
,
Rezaei MJ, Woodward JR, Ramirez J, Munroe P
(
2020
)
.
Data Augmentation for Heart Arrhythmia Classification
.
Proceedings - International Conference on Tools with Artificial Intelligence, ICTAI
.
vol.
2020-November
,
929
-
934
.
García-González J, Ramírez J, Howard DM, Brennan CH, Munroe PB, Keers R
(
2020
)
.
The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank
.
Translational Psychiatry
vol.
10
,
(
1
)
Van Duijvenboden S, Ramirez J, Young WJ, Tinker A, Munroe PB, Lambiase PD, Orini M
(
2020
)
.
Evaluating the Impact of Physiological Variability in Genome-Wide Association Studies of Resting Heart Rate
.
Computing in Cardiology
.
vol.
2020-September
,
Aung N, Young WJ, Van Duijvenboden S, Ramirez J, Petersen SE, Munroe PB
(
2020
)
.
Genetic Architecture of Quantitative Cardiovascular Traits: Blood Pressure, ECG and Imaging Phenotypes
.
Computing in Cardiology
.
vol.
2020-September
,
Ramirez J, Van Duijvenboden S, Young WJ, Tinker A, Lambiase PD, Munroe PB, Orini M
(
2020
)
.
Interaction between ECG and Genetic Markers of Coronary Artery Disease
.
Computing in Cardiology
.
Conference:
CinC 2020
from:
13/09/2020
to:
16/09/2020
,
vol.
2020-September
,
Palmieri F, Gomis P, Ruiz JE, Ferreira D, Martin-Yebra A, Pueyo E, Laguna P, Martinez JP et al.
(
2020
)
.
Potassium Monitoring from Multilead T-wave Morphology Changes during Hemodyalisis: Periodic Versus Principal Component Analysis
.
Computing in Cardiology
.
vol.
2020-September
,
Ramirez J, Van Duijvenboden S, Tinker A, Lambiase PD, Munroe PB, Orini M
(
2020
)
.
Sex Differences in the Morphology of RR-Matched T-waves
.
Computing in Cardiology
.
vol.
2020-September
,
Young WJ, Ramirez J, Van Duijvenboden S, Tinker A, Lambiase PD, Munroe PB, Orini M
(
2020
)
.
Will Genetic Data Significantly Change Cardiovascular Risk Prediction in Daily Practice?
.
Computing in Cardiology
.
vol.
2020-September
,
Weng LC, Hall AW, Choi SH, Jurgens SJ, Haessler J, Bihlmeyer NA, Grarup N, Lin H et al.
(
2020
)
.
Genetic determinants of electrocardiographic P-wave duration and relation to atrial fibrillation
.
Circulation: Genomic and Precision Medicine389
-
395
.
Van Duijvenboden S, Ramírez J, Young WJ, Mifsud B, Orini M, Tinker A, Munroe PB, Lambiase PD
(
2020
)
.
Genetic Basis and Prognostic Value of Exercise QT Dynamics
.
Circulation: Genomic and Precision Medicine
vol.
13
,
(
4
)
Ramírez J, van Duijvenboden S, Young WJ, Orini M, Lambiase PD, Munroe PB, Tinker A
(
2020
)
.
Common Genetic Variants Modulate the Electrocardiographic Tpeak-to-Tend Interval
.
American Journal of Human Genetics
vol.
106
,
(
6
)
764
-
778
.
Fung K, Biasiolli L, Hann E, Ramirez J, Lukaschuk E, Aung N, Paiva J, Werys K et al.
(
2020
)
.
3.2 First Genome-Wide Association Study of Cardiovascular Magnetic Resonance Derived Aortic Distensibility Reveals 7 Loci
.
Artery Research
.
vol.
25
,
Palmieri F, Gomis P, Ferreira D, Ruiz JE, Bergasa B, Martin-Yebra A, Bukhari HA, Pueyo E et al.
(
2019
)
.
T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients
.
2016 Computing in Cardiology Conference (CinC)
.
Conference:
2019 Computing in Cardiology Conference (CinC)
vol.
45
,
Bukhari HA, Palmieri F, Ferreira D, Potse M, Ramirez J, Laguna P, Sanchez C, Pueyo E
(
2019
)
.
Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels
.
2016 Computing in Cardiology Conference (CinC)
.
Conference:
2019 Computing in Cardiology Conference (CinC)
vol.
45
,
1
-
4
.
García-González J, Ramírez J, Howard D, Brennan C, Munroe P, Keers R
(
2019
)
.
The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank
.
Fung K, Ramírez J, Warren HR, Aung N, Lee AM, Tzanis E, Petersen SE, Munroe PB
(
2019
)
.
Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants
.
Scientific Reports
vol.
9
,
(
1
)
Munroe PB, Ramírez J, van Duijvenboden S
(
2019
)
.
Resting Heart Rate and Type 2 Diabetes: A Complex Relationship in Need of Greater Understanding
.
Journal of the American College of Cardiology
vol.
74
,
(
17
)
2175
-
2177
.
Ramírez J, van Duijvenboden S, Aung N, Laguna P, Pueyo E, Tinker A, Lambiase PD, Orini M et al.
(
2019
)
.
Cardiovascular Predictive Value and Genetic Basis of Ventricular Repolarization Dynamics
.
Circulation: Arrhythmia and Electrophysiology
vol.
12
,
(
10
)
e007549
-
e007549
.
Palmieri F, Ramírez J, Laguna P, Gomis P, Ferreira D, Ruiz JE, Bergasa B, Martín-Yebra A et al.
(
2019
)
.
T-Wave Morphology Changes as Surrogate for Blood Potassium Concentration in Hemodialysis Patients
.
Computing in Cardiology
.
vol.
2019-September
,
Bukhari HA, Palmieri F, Ferreira D, Potse M, Ramírez J, Laguna P, Sánchez C, Pueyo E
(
2019
)
.
Transmural Ventricular Heterogeneities Play a Major Role in Determining T-Wave Morphology at Different Extracellular Potassium Levels
.
Computing in Cardiology
.
vol.
2019-September
,
Ntalla I, Weng L-C, Cartwright J, Hall AW, Sveinbjornsson G, Tucker N, Choi SH, Chaffin M et al.
(
2019
)
.
Multi-ancestry GWAS of the electrocardiographic PR interval identifies 210 loci underlying cardiac conduction
.
Ramirez J, van Duijvenboden S, Tinker A, Lambiase P, Orini M, Munroe PB
(
2019
)
.
21 The cardiovascular predictive value and genetic basis of T-wave morphology
.
Heart
.
Conference:
Cardiac rhythm management
vol.
105
,
van Duijvenboden S, Ramirez J, Orini M, Tinker A, Munroe PB, Lambiase P
(
2019
)
.
22 Cardiac repolarization during exercise reveals independent prognostic information for cardiovascular risk prediction
.
Heart
.
Conference:
Cardiac Rhythm Management
vol.
105
,
Ramírez J, Duijvenboden SV, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A et al.
(
2018
)
.
Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system
.
Nature Communications
vol.
9
,
(
1
)
Ramirez J, Van Duijvenboden S, Laguna P, Pueyo E, Tinker A, Lambiase PD, Munroe PB, Orini M
(
2018
)
.
Assessing a Warping Methodology for the Identification of Increased Cardiovascular Risk Based on the HR Profile Morphology
.
Computing in Cardiology
.
Conference:
Computing in Cardiology
(
Maastricht, The Netherlands
)
from:
23/09/2018
to:
26/09/2018
,
vol.
2018-September
,
Palmieri F, Burattini L, Pablo Martinez J, Ramirez J
(
2018
)
.
T-Wave Morphology Restitution in Chronic Heart Failure Patient with Atrial Fibrillation
.
Computing in Cardiology
.
vol.
2018-September
,
Prins BP, Mead TJ, Brody JA, Sveinbjornsson G, Ntalla I, Bihlmeyer NA, van den Berg M, Bork-Jensen J et al.
(
2018
)
.
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6
.
Genome Biology
vol.
19
,
(
1
)
Ramírez J, Orini M, Mincholé A, Monasterio V, Cygankiewicz I, Bayés de Luna A, Martínez JP, Laguna P et al.
(
2017
)
.
Sudden cardiac death and pump failure death prediction in chronic heart failure by combining ECG and clinical markers in an integrated risk model
.
PLoS ONE
vol.
12
,
(
10
)
Ramirez J, Orini M, Tucker JD, Pueyo E, Laguna P
(
2017
)
.
Variability of Ventricular Repolarization Dispersion Quantified by Time-Warping the Morphology of the T-Waves
.
IEEE Transactions on Biomedical Engineering
vol.
64
,
(
7
)
1619
-
1630
.
Ramírez J, Orini M, Mincholé A, Monasterio V, Cygankiewicz I, de Luna AB, Martínez JP, Pueyo E et al.
(
2017
)
.
T-wave morphology restitution predicts sudden cardiac death in patients with chronic heart failure
.
Journal of the American Heart Association
vol.
6
,
(
5
)
Ramírez J, Orini M, Pueyo E, Laguna P
(
2017
)
.
Comparison of ECG T-wave Duration and morphology restitution markers for sudden cardiac death prediction in chronic heart Failure
.
Computing in Cardiology
.
vol.
44
,
1
-
4
.
Ramírez J, Orini M, Pueyo E, Laguna P
(
2017
)
.
Quantification of t-wave morphological variability using time-warping methods
.
IFMBE Proceedings
.
vol.
65
,
478
-
481
.
Ramírez J, Orini M, Pueyo E, Laguna P
(
2017
)
.
T-wave morphology restitution dependency with heart rate range and its association with sudden cardiac death in chronic heart failure
.
Computing in Cardiology
.
vol.
44
,
1
-
4
.
Ramirez J, Orini M, Derek Tucker J, Pueyo E, Laguna P
(
2016
)
.
An index for T-wave pointwise amplitude variability quantification
.
Computing in Cardiology
.
vol.
43
,
49
-
52
.
Lenis G, Menges R, Ramirez J, Cygankiewicz I, De Luna AB, Martinez JP, Laguna P, Dossel O
(
2016
)
.
Postextrasystolic T wave change to stratify risk of pump failure death in patients with chronic heart failure
.
Computing in Cardiology
.
vol.
43
,
33
-
36
.
Ramírez J, Monasterio V, Mincholé A, Llamedo M, Lenis G, Cygankiewicz I, Bayés De Luna A, Malik M et al.
(
2015
)
.
Automatic SVM classification of sudden cardiac death and pump failure death from autonomic and repolarization ECG markers
.
Journal of Electrocardiology
vol.
48
,
(
4
)
551
-
557
.
Ramírez J, Laguna P, Bayés De Luna A, Malik M, Pueyo E
(
2015
)
.
Erratum: QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death (Journal of Electrocardiology (2014) 47:6 (842-8))
.
Journal of Electrocardiology
vol.
48
,
(
1
)
128
-
129
.
Ramírez J, Laguna P, Bayés De Luna A, Malik M, Pueyo E
(
2014
)
.
QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure: Relation to sudden cardiac death
.
Journal of Electrocardiology
vol.
47
,
(
6
)
842
-
848
.
Ramírez J, Cygankiewicz I, Laguna P, Malik M, Pueyo E
(
2014
)
.
Circadian pattern and sex differences of QT/RR and T-peak-to-end/RR curvatures and slopes in chronic heart failure patients
.
Computing in Cardiology
.
vol.
41
,
173
-
176
.
Ramirez J, Minchole A, Bolea J, Laguna P, Pueyo E
(
2013
)
.
Prediction of sudden cardiac death in chronic heart failure patients by analysis of restitution dispersion
.
Computing in Cardiology
.
vol.
40
,
1
-
4
.
Ramirez J, Minchole A, Laguna P, Pueyo E
(
2012
)
.
Characterization of cardiac repolarization response to heart rate changes provoked by a tilt test
.
Computing in Cardiology
.
vol.
39
,
673
-
676
.