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Publications: Dr Clare Relton

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Holt H, Relton C, Talaei M, Symons J, Davies MR, Jolliffe DA, Vivaldi G, Tydeman F et al. ( 2023 ) . Cohort Profile: Longitudinal population-based study of COVID-19 in UK adults (COVIDENCE UK) . International journal of epidemiology vol. 52 , ( 1 ) e46 - e56 .
Jolliffe DA, Holt H, Greenig M, Talaei M, Perdek N, Pfeffer P, Vivaldi G, Maltby S et al. ( 2022 ) . Effect of a test-and-treat approach to vitamin D supplementation on risk of all cause acute respiratory tract infection and covid-19: Phase 3 randomised controlled trial (CORONAVIT) . The BMJ
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young KS, Davies MR et al. ( 2022 ) . Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK) . Thorax vol. 77 , ( 9 ) 900 - 912 .
Verweij ME, Gal R, Burbach JPM, Young-Afat DA, van der Velden JM, van der Graaf R, May AM, Relton C et al. ( 2022 ) . Most patients reported positively or neutrally of having served as controls in the trials within cohorts design . Journal of Clinical Epidemiology vol. 148 , 39 - 47 .
Holt H, Relton C, Talaei M, Symons J, Davies M, Jolliffe D, Vivaldi G, Tydeman F et al. ( 2022 ) . Cohort Profile: Longitudinal population-based study of COVID-19 in UK adults (COVIDENCE UK) .
Jolliffe D, Holt H, Greenig M, Talaei M, Perdek N, Pfeffer P, Vivaldi G, Maltby S et al. ( 2022 ) . Vitamin D Supplements for Prevention of COVID-19 or other Acute Respiratory Infections: a Phase 3 Randomised Controlled Trial (CORONAVIT) .
Campbell F, Booth A, Carroll C, Lee A, Relton C ( 2022 ) . Qualitative evidence syntheses of attitudes and preferences to inform guidelines on infant feeding in the context of Ebola Virus Disease (EVD) transmission risk . PLoS Neglected Tropical Diseases vol. 16 , ( 3 )
Mc Cord KA, Imran M, Rice DB, McCall SJ, Kwakkenbos L, Sampson M, Fröbert O, Gale C et al. ( 2022 ) . Reporting transparency and completeness in Trials: Paper 2 - reporting of randomised trials using registries was often inadequate and hindered the interpretation of results . Journal of Clinical Epidemiology vol. 141 , 175 - 186 .
Imran M, Mc Cord K, McCall SJ, Kwakkenbos L, Sampson M, Fröbert O, Gale C, Hemkens LG et al. ( 2022 ) . Reporting transparency and completeness in trials: Paper 3 – trials conducted using administrative databases do not adequately report elements related to use of databases . Journal of Clinical Epidemiology vol. 141 , 187 - 197 .
McCall SJ, Imran M, Hemkens LG, Mc Cord K, Kwakkenbos L, Sampson M, Jawad S, Zwarenstein M et al. ( 2022 ) . Reporting transparency and completeness in trials: Paper 4 - reporting of randomised controlled trials conducted using routinely collected electronic records – room for improvement . Journal of Clinical Epidemiology vol. 141 , 198 - 209 .
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al. ( 2021 ) . Risk Factors for Developing COVID-19: A Population-Based Longitudinal Study (COVIDENCE UK) . Thorax
Stephenson J, Smith CM, Goyder EC, Holding E, Haywood A, Crum A, Blackburn J, Cooke J et al. ( 2021 ) . Cohort Profile Update: The Yorkshire Health Study . International Journal of Epidemiology vol. 50 , ( 4 ) 1070 - 1070D .
Cockayne S, Pighills A, Fairhurst C, Adamson J, Crossland S, Drummond A, Hewitt C, Rodgers S et al. ( 2021 ) . Home hazard assessment and environmental modification to prevent falls in older people: the OTIS trial . F1000Research vol. 10 ,
Kwakkenbos L, Imran M, McCall SJ, McCord KA, Fröbert O, Hemkens LG, Zwarenstein M, Relton C et al. ( 2021 ) . CONSORT extension for the reporting of randomised controlled trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE): Checklist with explanation and elaboration . The BMJ vol. 373 ,
Imran M, Kwakkenbos L, McCall SJ, McCord KA, Fröbert O, Hemkens LG, Zwarenstein M, Relton C et al. ( 2021 ) . Methods and results used in the development of a consensus-driven extension to the Consolidated Standards of Reporting Trials (CONSORT) statement for trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE) . BMJ Open vol. 11 , ( 4 )
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al. ( 2021 ) . Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK) . MedRvx
Cockayne S, Pighills A, Adamson J, Fairhurst C, Crossland S, Drummond A, Hewitt CE, Rodgers S et al. ( 2021 ) . Home environmental assessments and modification delivered by occupational therapists to reduce falls in people aged 65 years and over: The OTIS RCT . Health Technology Assessment vol. 25 , ( 46 )
Carroll C, Booth A, Campbell F, Relton C ( 2020 ) . Qualitative evidence synthesis of values and preferences to inform infant feeding in the context of non-HIV transmission risk . PLoS ONE vol. 15 , ( 12 December )
Fibert P, Relton C ( 2020 ) . What families in the UK use to manage attention-deficit/hyperactivity disorder (ADHD): A survey of resource use . BMJ Paediatrics Open vol. 4 , ( 1 )
Relton C, Crowder M, Blake M, Strong M ( 2020 ) . Fresh street: the development and feasibility of a place-based, subsidy for fresh fruit and vegetables . Journal of Public Health
Carroll C, Booth A, Campbell F, Relton C ( 2020 ) . What are the implications of zika virus for infant feeding? A synthesis of qualitative evidence concerning congenital zika syndrome (czs) and comparable conditions . PLoS Neglected Tropical Diseases vol. 14 , ( 10 ) 1 - 30 .
Vanderhout SM, Aglipay M, Birken C, Li P, O'Connor DL, Thorpe K, Constantin E, Davis MA et al. ( 2020 ) . Cow's Milk Fat Obesity pRevention Trial (CoMFORT): a primary care embedded randomised controlled trial protocol to determine the effect of cow's milk fat on child adiposity . BMJ open vol. 10 , ( 5 )
Relton C ( 2020 ) . Randomised Controlled Trials . Homeopathy vol. 109 , ( 01 ) a1 - a28 .
Ahmed HU, Berge V, Bottomley D, Cross W, Heer R, Kaplan R, Leslie T, Parker C et al. ( 2020 ) . Correction: Corrigendum: Can we deliver randomized trials of focal therapy in prostate cancer? (Nature Reviews Clinical Oncology, (2014), 11, 8, (482-491), 10.1038/nrclinonc.2014.44) . Nature Reviews Clinical Oncology
Addison R, Hill L, Bode L, Robertson B, Choudhury B, Young D, Wright C, Relton C et al. ( 2020 ) . Development of a biochemical marker to detect current breast milk intake . Maternal and Child Nutrition vol. 16 , ( 1 )
Relton C, Zwarenstein M, Hemkens LG, Verkooijen HM, Frobert O ( 2019 ) . Health System Trials . TRIALS . vol. 20 ,
Juszczak E, Kwakkenbos L, McCall S, Imran M, Hemkens LG, Zwarenstein M, Frobert O, Relton C et al. ( 2019 ) . Introducing the CONsolidated Standards of Reporting Trials (CONSORT) statement for randomised controlled trials (RCTs) using cohorts and routinely collected health data . TRIALS . vol. 20 ,
Relton C, Nickolls B, Zwarenstein M, Hemken LG, Uher R, Frobert O, Fibert P, Imran M et al. ( 2019 ) . Review of use of the Trials within Cohorts (TwiCs) design approach . TRIALS . Conference: 5th International Clinical Trials Methodology Conference (ICTMC 2019) from: 21/10/2019 to: 24/10/2019 , vol. 20 ,
Wylie H, Cahill F, Santaolalla A, Moss CL, Enting D, Amery S, Chatterton K, Khan MS et al. ( 2019 ) . Graham Roberts Study protocol: First 'trials within cohort study' for bladder cancer . BMJ Open vol. 9 , ( 9 )
Anokye N, Coyle K, Relton C, Walters S, Strong M, Fox-Rushby J ( 2019 ) . Cost-effectiveness of offering an area-level financial incentive on breast feeding: A within-cluster randomised controlled trial analysis . Archives of Disease in Childhood
Fibert P, Peasgood T, Relton C ( 2019 ) . Rethinking ADHD intervention trials: feasibility testing of two treatments and a methodology . European Journal of Pediatrics vol. 178 , ( 7 ) 983 - 993 .
Relton C ( 2019 ) . Valuing breastfeeding: Can financial incentives for breastfeeding help strengthen the UK breastfeeding culture? . Evidence Based Midwifery vol. 17 , ( 1 ) 4 - 9 .
McCaffery J, Mitchell A, Fairhurst C, Cockayne S, Rodgers S, Relton C, Torgerson DJ ( 2019 ) . Does handwriting the name of a potential trial participant on an invitation letter improve recruitment rates? A randomised controlled study within a trial [version 1; peer review: 2 approved] . F1000Research vol. 8 ,
Miller DG, Kim SYH, Li X, Dickert NW, Flory J, Runge CP, Relton C ( 2018 ) . Ethical Acceptability of Postrandomization Consent in Pragmatic Clinical Trials . JAMA Netw Open vol. 1 , ( 8 ) e186149 - e186149 .
Cockayne S, Pighills A, Adamson J, Fairhurst C, Drummond A, Hewitt C, Rodgers S, Ronaldson SJ et al. ( 2018 ) . Can occupational therapist-led home environmental assessment prevent falls in older people? A modified cohort randomised controlled trial protocol . BMJ Open vol. 8 , ( 9 ) e022488 - e022488 .
Kwakkenbos L, Imran M, McCord KA, Sampson M, Fröbert O, Gale C, Hemkens LG, Langan SM et al. ( 2018 ) . Protocol for a scoping review to support development of a CONSORT extension for randomised controlled trials using cohorts and routinely collected health data . BMJ Open vol. 8 , ( 8 )
Viksveen P, Fibert P, Relton C ( 2018 ) . Homeopathy in the treatment of depression: a systematic review . European Journal of Integrative Medicine vol. 22 , 22 - 36 .
Whelan B, Relton C, Johnson M, Strong M, Thomas KJ, Umney D, Renfrew M ( 2018 ) . Valuing Breastfeeding: Health Care Professionals’ Experiences of Delivering a Conditional Cash Transfer Scheme for Breastfeeding in Areas With Low Breastfeeding Rates . SAGE Open vol. 8 , ( 2 )
Fibert P, Relton C, Peasgood T, Daley D ( 2018 ) . Protocol for the STAR (Sheffield Treatments for ADHD) project: An internal pilot study assessing the feasibility of the Trials within Cohorts (TwiCs) design to test the effectiveness of interventions for children with ADHD . Pilot and Feasibility Studies vol. 4 , ( 1 )
Becker F, Anokye N, de Bekker-Grob EW, Higgins A, Relton C, Strong M, Fox-Rushby J ( 2018 ) . Women's preferences for alternative financial incentive schemes for breastfeeding: A discrete choice experiment . PLoS One vol. 13 , ( 4 ) Article 0194231 , e0194231 - e0194231 .
Kearns B, Chilcott J, Relton C, Whyte S, Woods HB, Nickerson C, Loban A ( 2018 ) . The association between long-term conditions and uptake of population-based screening for colorectal cancer: Results from two English cohort studies . Cancer Management and Research vol. 10 , 637 - 645 .
Kim SYH, Flory J, Relton C ( 2018 ) . Rejoinder . Clinical Trials vol. 15 , ( 1 ) 27 - 28 .
Johnson M, Whelan B, Relton C, Thomas K, Strong M, Scott E, Renfrew MJ ( 2018 ) . Valuing breastfeeding: A qualitative study of women's experiences of a financial incentive scheme for breastfeeding . BMC Pregnancy and Childbirth vol. 18 , ( 1 )
Kwakkenbos L, Juszczak E, Hemkens LG, Sampson M, Fröbert O, Relton C, Gale C, Zwarenstein M et al. ( 2018 ) . Protocol for the development of a CONSORT extension for RCTs using cohorts and routinely collected health data . Res Integr Peer Rev vol. 3 ,
Relton C, Strong M, Thomas KJ, Whelan B, Walters SJ, Burrows J, Scott E, Viksveen P et al. ( 2017 ) . Effect of financial incentives on breastfeeding a cluster randomized clinical trial . JAMA Pediatrics vol. 172 , ( 2 )
Kim SY, Flory J, Relton C ( 2017 ) . Ethics and practice of Trials within Cohorts: An emerging pragmatic trial design . Clin Trials vol. 15 , ( 1 ) 9 - 16 .
Viksveen P, Relton C ( 2017 ) . Depressed patients’ experiences with and perspectives on treatment provided by homeopaths. A qualitative interview study embedded in a trial . European Journal of Integrative Medicine vol. 15 , 73 - 80 .
Viksveen P, Relton C, Nicholl J ( 2017 ) . Benefits and challenges of using the cohort multiple randomised controlled trial design for testing an intervention for depression . Trials vol. 18 , ( 1 ) Article 308 ,
Viksveen P, Relton C, Nicholl J ( 2017 ) . Depressed patients treated by homeopaths: A randomised controlled trial using the "cohort multiple randomised controlled trial" (cmRCT) design . Trials vol. 18 , ( 1 )
Relton C, Cooper K, Viksveen P, Fibert P, Thomas K ( 2017 ) . Prevalence of homeopathy use by the general population worldwide: a systematic review . Homeopathy vol. 106 , ( 2 ) 69 - 78 .
Green MA, Little E, Cooper R, Relton C, Strong M ( 2016 ) . Investigation of social, demographic and health variations in the usage of prescribed and over-the-counter medicines within a large cohort (South Yorkshire, UK) . BMJ Open vol. 6 , ( 9 )
Li J, Green M, Kearns B, Holding E, Smith C, Haywood A, Cooper C, Strong M et al. ( 2016 ) . Patterns of multimorbidity and their association with health outcomes within Yorkshire, England: Baseline results from the Yorkshire Health Study . BMC Public Health vol. 16 , ( 1 )
Zakrzewska JM, Relton C ( 2016 ) . Future Directions for Surgical Trial Designs in Trigeminal Neuralgia . Neurosurgery Clinics of North America vol. 27 , ( 3 ) 353 - 363 .
Green MA, Li J, Relton C, Strong M, Kearns B, Wu M, Bissell P, Blackburn J et al. ( 2016 ) . Cohort profile: The yorkshire health study . International Journal of Epidemiology vol. 45 , ( 3 ) 707 - 712 .
Green MA, Strong M, Razak F, Subramanian SV, Relton C, Bissell P ( 2016 ) . Who are the obese? A cluster analysis exploring subgroups of the obese . Journal of Public Health (United Kingdom) vol. 38 , ( 2 ) 258 - 264 .
Fibert P, Relton C, Heirs M, Bowden D ( 2016 ) . A comparative consecutive case series of 20 children with a diagnosis of ADHD receiving homeopathic treatment, compared with 10 children receiving usual care . Homeopathy vol. 105 , ( 2 ) 194 - 201 .
Young-Afat DA, Verkooijen HAM, van Gils CH, van der Velden JM, Burbach JP, Elias SG, van Delden JJ, Relton C et al. ( 2016 ) . Brief Report: Staged-informed Consent in the Cohort Multiple Randomized Controlled Trial Design . Epidemiology vol. 27 , ( 3 ) 389 - 392 .
van der Velden JM, Verkooijen HM, Ayoung-Afat D, Burbach JPM, van Vulpen M, Relton C, van Gils CH, May AM et al. ( 2016 ) . The cohort multiple randomized controlled trial design: A valid and efficient alternative to pragmatic trials? . International Journal of Epidemiology vol. 46 , ( 1 ) 96 - 102 .
Relton C, Strong M, Renfrew MJ, Thomas K, Burrows J, Whelan B, Whitford HM, Scott E et al. ( 2016 ) . Cluster randomised controlled trial of a financial incentive for mothers to improve breast feeding in areas with low breastfeeding rates: the NOSH study protocol . BMJ Open vol. 6 , ( 4 ) e010158 - e010158 .
Anastasiadis E, Ahmed HU, Relton C, Emberton M ( 2015 ) . A novel randomised controlled trial design in prostate cancer . BJU International vol. 116 , ( 1 ) 6 - 8 .
Clegg A, Relton C, Young J, Witham M ( 2015 ) . Improving recruitment of older people to clinical trials: Use of the cohort multiple randomised controlled trial design . Age and Ageing vol. 44 , ( 4 ) 547 - 550 .
Wu M, Brazier JE, Kearns B, Relton C, Smith C, Cooper CL ( 2015 ) . Examining the impact of 11 long-standing health conditions on health-related quality of life using the EQ-5D in a general population sample . European Journal of Health Economics vol. 16 , ( 2 ) 141 - 151 .
Whitford H, Whelan B, Van Cleemput P, Thomas K, Renfrew M, Strong M, Scott E, Relton C ( 2015 ) . Encouraging breastfeeding: Financial incentives . Practising Midwife vol. 18 , ( 2 ) 18 - 21 .
Golfam M, Beall R, Brehaut J, Saeed S, Relton C, Ashbury FD, Little J ( 2015 ) . Comparing alternative design options for chronic disease prevention interventions . European Journal of Clinical Investigation vol. 45 , ( 1 ) 87 - 99 .
Whelan B, Thomas KJ, Cleemput PV, Whitford H, Strong M, Renfrew MJ, Scott E, Relton C ( 2014 ) . Healthcare providers' views on the acceptability of financial incentives for breastfeeding: A qualitative study . BMC Pregnancy and Childbirth vol. 14 , ( 1 )
Relton C, Li J, Strong M, Holdsworth M, Cooper R, Green M, Bissell P ( 2014 ) . Deprivation, clubs and drugs: Results of a UK regional population-based cross-sectional study of weight management strategies . BMC Public Health vol. 14 , ( 1 )
Harris PE, Cooper KL, Relton C, Thomas KJ ( 2014 ) . Prevalence of visits to massage therapists by the general population: Asystematic review . Complementary Therapies in Clinical Practice vol. 20 , ( 1 ) 16 - 20 .
Ashbury FD, Little J, Ioannidis JPA, Kreiger N, Palmer LJ, Relton C, Taylor P ( 2014 ) . A vision for chronic disease prevention and intervention research: Report from a workshop . Canadian Journal of Public Health vol. 105 , ( 2 )
Ahmed HU, Berge V, Bottomley D, Cross W, Heer R, Kaplan R, Leslie T, Parker C et al. ( 2014 ) . Can we deliver randomized trials of focal therapy in prostate cancer? . Nature Reviews Clinical Oncology vol. 11 , ( 8 ) 482 - 491 .
Viksveen P, Relton C ( 2014 ) . Depression treated by homeopaths: A study protocol for a pragmatic cohort multiple randomised controlled trial . Homeopathy vol. 103 , ( 2 ) 147 - 152 .
Wu M, Brazier J, Relton C, Cooper C, Smith C, Blackburn J ( 2014 ) . Examining the incremental impact of long-standing health conditions on subjective well-being alongside the EQ-5D . Health and Quality of Life Outcomes vol. 12 , ( 1 )
Roberts ER, Baumgartner S, Mathie RT, Relton C, Thompson E, Tournier A ( 2014 ) . HRI Barcelona 2013: Inaugural conference brings homeopathy research into the spotlight . Homeopathy . vol. 103 , 58 - 61 .
Peckham EJ, Relton C, Raw J, Walters C, Thomas K, Smith C, Kapur K, Said E ( 2014 ) . Interim results of a randomised controlled trial ofhomeopathic treatment for irritable bowel syndrome . Homeopathy vol. 103 , ( 3 ) 172 - 177 .
Relton C, Viksveen P, Kessler U ( 2014 ) . The Making cases count intiative . Complementary Therapies in Medicine vol. 22 , ( 4 ) 621 - 624 .
Cooper KL, Harris PE, Relton C, Thomas KJ ( 2013 ) . Prevalence of visits to five types of complementary and alternative medicine practitioners by the general population: A systematic review . Complementary Therapies in Clinical Practice vol. 19 , ( 4 ) 214 - 220 .
Kearns B, Ara R, Young T, Relton C ( 2013 ) . Association between body mass index and health-related quality of life, and the impact of self-reported long-term conditions - Cross-sectional study from the south Yorkshire cohort dataset . BMC Public Health vol. 13 , ( 1 )
Relton C ( 2013 ) . Implications of the 'placebo effect' for CAM research . Complementary Therapies in Medicine vol. 21 , ( 2 ) 121 - 124 .
Peckham EJ, Relton C, Raw J, Walters C, Thomas K, Smith C ( 2012 ) . A protocol for a trial of homeopathic treatment for irritable bowel syndrome . BMC Complementary and Alternative Medicine vol. 12 ,
Harris PE, Cooper KL, Relton C, Thomas KJ ( 2012 ) . Prevalence of complementary and alternative medicine (CAM) use by the general population: A systematic review and update . International Journal of Clinical Practice vol. 66 , ( 10 ) 924 - 939 .
Relton C, O'Cathain A, Nicholl J ( 2012 ) . A pilot 'cohort multiple randomised controlled trial' of treatment by a homeopath for women with menopausal hot flushes . Contemporary Clinical Trials vol. 33 , ( 5 ) 853 - 859 .
Relton C, Strong M, Holdsworth M ( 2012 ) . Plastic food packaging encourages obesity . BMJ (Clinical research ed.) vol. 344 ,
Relton C, Strong M, Li J ( 2011 ) . The 'Pounds for Pounds' weight loss financial incentive scheme: An evaluation of a pilot in NHS Eastern and Coastal Kent . Journal of Public Health vol. 33 , ( 4 ) 536 - 542 .
Relton C, Bissell P, Smith C, Blackburn J, Cooper CL, Nicholl J, Tod A, Copeland R et al. ( 2011 ) . South Yorkshire Cohort: A 'cohort trials facility' study of health and weight - Protocol for the recruitment phase . BMC Public Health vol. 11 ,
Cooper KL, Relton C ( 2010 ) . Homeopathy for insomnia: Summary of additional RCT published since systematic review . Sleep Medicine Reviews vol. 14 , ( 6 )
Cooper KL, Relton C ( 2010 ) . Homeopathy for insomnia: A systematic review of research evidence . Sleep Medicine Reviews vol. 14 , ( 5 ) 329 - 337 .
Relton C, Torgerson D, O'Cathain A, Nicholl J ( 2010 ) . Rethinking pragmatic randomised controlled trials: Introducing the "cohort multiple randomised controlled trial" design . BMJ (Online) vol. 340 , ( 7753 ) 963 - 967 .
Relton C, Smith C, Raw J, Walters C, Adebajo AO, Thomas KJ, Young TA ( 2009 ) . Healthcare provided by a homeopath as an adjunct to usual care for Fibromyalgia (FMS): results of a pilot Randomised Controlled Trial . Homeopathy vol. 98 , ( 2 ) 77 - 82 .
Thompson EA, Relton C ( 2009 ) . Designing clinical trials of homeopathy for menopausal symptoms: A review of the literature . Menopause International vol. 15 , ( 1 ) 31 - 34 .
Relton C, Thomas KJ, O'Cathain A ( 2009 ) . Response to Leslie Rose . Homeopathy vol. 98 , ( 1 )
Relton C, O'Cathain A, Thomas KJ ( 2008 ) . 'Homeopathy': Untangling the debate . Homeopathy vol. 97 , ( 3 ) 152 - 155 .
Relton C, Chatfield K, Partington H, Foulkes L ( 2007 ) . Patients treated by homeopaths registered with the Society of Homeopaths: a pilot study . Homeopathy vol. 96 , ( 2 ) 87 - 89 .
Relton C, Weatherley-Jones E ( 2005 ) . Homeopathy service in a National Health Service community menopause clinic: Audit of clinical outcomes . Journal of the British Menopause Society vol. 11 , ( 2 ) 72 - 73 .
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