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Research

Publications: Dr Peter Thorpe

Klemm C, Howell RSM, Thorpe PH ( 2022 ) . ScreenGarden: a shinyR application for fast and easy analysis of plate-based high-throughput screens . BMC Bioinformatics vol. 23 , ( 1 )
Nitika, Zheng B, Ruan L, Kline JT, Omkar S, Sikora J, Texeira Torres M, Wang Y et al. ( 2022 ) . Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications . PLoS Biology vol. 20 , ( 10 ) e3001839 - e3001839 .
Klemm C, Wood H, Thomas GH, Ólafsson G, Torres MT, Thorpe PH ( 2021 ) . Forced association of SARS-CoV-2 proteins with the yeast proteome perturb vesicle trafficking . Microbial Cell vol. 8 , ( 12 ) 280 - 296 .
Mishra PK, Wood H, Stanton J, Au WC, Eisenstatt JR, Boeckmann L, Sclafani RA, Weinreich M et al. ( 2021 ) . Cdc7-mediated phosphorylation of Cse4 regulates high-fidelity chromosome segregation in budding yeast . Molecular Biology of the Cell vol. 32 , ( 21 )
Klemm C, Thorpe PH, Ólafsson G ( 2021 ) . Cell-cycle phospho-regulation of the kinetochore . Current Genetics vol. 67 , ( 2 ) 177 - 193 .
Howell RSM, Klemm C, Thorpe PH, Csikasz-Nagy A ( 2020 ) . Unifying the mechanism of mitotic exit control in a spatiotemporal logical model . PLoS Biology vol. 18 , ( 11 )
Herrero E, Stinus S, Bellows E, Berry LK, Wood H, Thorpe PH ( 2020 ) . Asymmetric Transcription Factor Partitioning During Yeast Cell Division Requires the FACT Chromatin Remodeler and Cell Cycle Progression . Genetics vol. 216 , ( 3 ) 701 - 716 .
Herrero E, Stinus S, Bellows E, Berry LK, Wood H, Thorpe PH ( 2020 ) . Asymmetric transcription factor partitioning during yeast cell division requires the fact chromatin remodeler and cell cycle progression . Genetics vol. 216 , ( 3 ) 701 - 716 .
Ólafsson G, Thorpe PH ( 2020 ) . Polo kinase recruitment via the constitutive centromere-associated network at the kinetochore elevates centromeric RNA . PLoS Genetics vol. 16 , ( 8 )
Berry LK, Thomas GH, Thorpe PH ( 2020 ) . CATS: Cas9-assisted tag switching. A high-throughput method for exchanging genomic peptide tags in yeast . BMC Genomics vol. 21 , ( 1 )
Garcia E, Guo W, Kumar S, Görlitz F, Sparks H, Alexandrov Y, Munro I, Kelly DJ et al. ( 2020 ) . FLIM, FRET and high content analysis . Progress in Biomedical Optics and Imaging - Proceedings of SPIE . Conference: SPIE BiOS vol. 11244 ,
Howell RSM, Csikász-Nagy A, Thorpe PH ( 2019 ) . Synthetic Physical Interactions with the Yeast Centrosome . G3 (Bethesda) vol. 9 , ( 7 ) 2183 - 2194 .
Howell RSM, Csikász-Nagy A, Thorpe PH ( 2019 ) . Synthetic Physical Interactions with the Yeast Centrosome . G3 (Bethesda) vol. 9 , ( 7 ) 2183 - 2194 .
Mishra PK, Olafsson G, Boeckmann L, Westlake TJ, Jowhar ZM, Dittman LE, Baker RE, D'Amours D et al. ( 2019 ) . Cell cycle dependent association of polo kinase Cdc5 with CENP-A contributes to faithful chromosome segregation in budding yeast . Mol Biol CellmbcE18090584 - mbcE18090584 .
Guo W, Kumar S, Görlitz F, Garcia E, Alexandrov Y, Munro I, Kelly DJ, Warren S et al. ( 2019 ) . Automated Fluorescence Lifetime Imaging High-Content Analysis of Förster Resonance Energy Transfer between Endogenously Labeled Kinetochore Proteins in Live Budding Yeast Cells . SLAS Technol vol. 24 , ( 3 ) 308 - 320 .
Ólafsson G, Thorpe PH ( 2018 ) . Rewiring the budding yeast proteome using synthetic physical interactions . Methods in Molecular Biology , vol. 1672 ,
Ledesma-Fernández E, Thorpe PH, de Bruin RAM ( 2016 ) . Bringing Functional Genomics into Focus . Cell Systems vol. 3 , ( 3 ) 214 - 216 .
Olafsson G, Thorpe PH ( 2016 ) . Synthetic Physical Interactions Map Kinetochore-Checkpoint Activation Regions . G3-GENES GENOMES GENETICS vol. 6 , ( 8 ) 2531 - 2542 .
Berry LK, Ólafsson G, Ledesma-Fernández E, Thorpe PH ( 2016 ) . Synthetic protein interactions reveal a functional map of the cell . eLife vol. 5 , ( APRIL2016 )
Herrero E, Thorpe PH ( 2016 ) . Synergistic Control of Kinetochore Protein Levels by Psh1 and Ubr2 . PLoS Genet vol. 12 , ( 2 )
Ólafsson G, Thorpe PH ( 2015 ) . Synthetic physical interactions map kinetochore regulators and regions sensitive to constitutive Cdc14 localization . Proceedings of the National Academy of Sciences of the United States of America vol. 112 , ( 33 ) 10413 - 10418 .
Ledesma-Fernández E, Thorpe PH ( 2015 ) . Fluorescent foci quantitation for high-throughput analysis . J Biol Methods vol. 2 , ( 2 )