Publications: Mr Polychronis Kemos

Atia O, Klomberg RCW, de Ridder L, Kemos P, Ruemmele FM, Kang B, Choi S, Choe B et al. ( 2023 ) . Validation of predictive models for disease outcomes in paediatric ulcerative colitis: A multicentre prospective inception cohort . Alimentary Pharmacology & Therapeutics vol. 58 , ( 2 ) 182 - 190 .

Klomberg R, Kaper D, Barendregt D, Vuijk S, Schreurs M, Charrout M, Ruemmele F, Kemos P et al. ( 2023 ) . P243 The association between serological markers ASCA and ANCA and response to induction treatment in therapy-naïve children with inflammatory bowel disease: an international prospective study . Journal of Crohn's and Colitis . vol. 17 , i395 - i396 .

Loey Mak LY, Koffas A, Dolman G, Saleh H, Kemos P, Riddell A, Gill U, Kennedy P ( 2022 ) . P75 Inter-ethnic differences of quantitative hepatitis B surface antigen (qHBsAg) in predicting highly viraemic pregnancy with chronic hepatitis B infection . Conference: Abstractsa87 - a89 .

Delalande JM, Nagy N, McCann CJ, Natarajan D, Cooper JE, Carreno G, Dora D, Campbell A et al. ( 2022 ) . Corrigendum: TALPID3/KIAA0586 Regulates Multiple Aspects of Neuromuscular Patterning During Gastrointestinal Development in Animal Models and Human . Frontiers in Molecular Neuroscience vol. 15 ,

Klomberg RCW, Aardoom MA, Kemos P, Rizopoulos D, Ruemmele FM, Croft NM, de Ridder L, Neyt M et al. ( 2022 ) . High Impact of Pediatric Inflammatory Bowel Disease on Caregivers’ Work Productivity and Daily Activities: An International Prospective Study . The Journal of Pediatrics vol. 246 , 95 - 102.e4 .

Heredia M, Costes LMM, Tindemans I, Aardoom MA, Klomberg RCW, Kemos P, Joosse ME, van Haaften DH et al. ( 2022 ) . P045 TIGIT expression differentiates regulatory from inflammatory Th1* gut-homing effector CD4+ T cells in inflammatory bowel disease patients . Journal of Crohn's and Colitis . vol. 16 , i161 - i161 .

Heredia M, Charrout M, Klomberg RCW, Aardoom MA, Jongsma MME, Kemos P, van Haaften DH, Tuk B et al. ( 2022 ) . P061 Circulating inflammatory protein and cellular profiles at time of diagnosis classify inflammatory bowel disease patients according to their underlying immune response and clinical disease course . Journal of Crohn's and Colitis . vol. 16 , i171 - i171 .

Klomberg R, van der Wal H, Sarbagili C, Kemos P, Ruemelle F, Croft N, de Ridder L, Levine A ( 2022 ) . P146 Initial response to induction treatment more important than type of induction treatment for achieving sustained steroid free remission at 1 year in new-onset paediatric Crohn’s disease . Journal of Crohn's and Colitis . vol. 16 , i226 - i226 .

Klomberg R, Kemos P, Chondrou P, Croft N, de Ridder L ( 2022 ) . P678 Rare and severe complications in paediatric Inflammatory Bowel Disease: results of 5 years of international collaboration through the PIBD-SETQuality Safety Registry . Journal of Crohn's and Colitis . vol. 16 , i582 - i582 .

Heredia M, Charrout M, Klomberg RCW, Aardoom MA, Jongsma MME, Kemos P, van Haaften DH, Tuk B et al. ( 2022 ) . Circulating inflammatory protein and cellular profiles at time of diagnosis classify inflammatory bowel disease patients according to their underlying immune response and clinical disease course . JOURNAL OF CROHNS & COLITIS . vol. 16 , I171 - I171 .

Klomberg R, van der Wal H, Sarbagili C, Kemos P, Ruemelle F, Croft N, de Ridder L, Levine A ( 2022 ) . Initial response to induction treatment more important than type of induction treatment for achieving sustained steroid free remission at 1 year in new-onset paediatric Crohn's disease . JOURNAL OF CROHNS & COLITIS . vol. 16 , I226 - I226 .

Klomberg R, Kemos P, Chondrou P, Croft N, de Ridder L ( 2022 ) . Rare and severe complications in paediatric Inflammatory Bowel Disease: results of 5 years of international collaboration through the PIBD-SETQuality Safety Registry . JOURNAL OF CROHNS & COLITIS . vol. 16 , I582 - I582 .

Heredia M, Costes LMM, Tindemans I, Aardoom MA, Klomberg RCW, Kemos P, Joosse ME, van Haaften DH et al. ( 2022 ) . TIGIT expression differentiates regulatory from inflammatory Th1*gut-homing effector CD4+T cells in inflammatory bowel disease patients . JOURNAL OF CROHNS & COLITIS . vol. 16 , I161 - I161 .

Delalande JM, Nagy N, McCann CJ, Natarajan D, Cooper JE, Carreno G, Dora D, Campbell A et al. ( 2021 ) . TALPID3/KIAA0586 Regulates Multiple Aspects of Neuromuscular Patterning During Gastrointestinal Development in Animal Models and Human . Frontiers in Molecular Neuroscience vol. 14 ,

Aardoom MA, Klomberg RCW, Kemos P, Ruemmele FM, van Ommen H, de Ridder L, Croft NM ( 2021 ) . The incidence and characteristics of venous thromboembolisms in paediatric-onset inflammatory bowel disease; a prospective international cohort study based on the PIBD-SETQuality Safety Registry . J Crohns Colitis

Heredia M, Costes L, Tindemans I, Aardoom M, Klomberg R, Kemos P, Joosse M, van Haaften D et al. ( 2021 ) . P012 Low frequencies of circulating inhibitory TIGIT+CD38+ effector T cells identify an immunologically distinct subgroup of pediatric patients with severe Crohn’s disease . Journal of Crohn's and Colitis . vol. 15 , s134 - s134 .

Heredia M, Charrout M, Klomberg R, Aardoom M, Jongsma M, Kemos P, van Haaften D, Tuk B et al. ( 2021 ) . P021 Circulating inflammatory protein and cellular profiles at time of diagnosis classify inflammatory bowel disease patients according to their underlying immune response and clinical disease course . Journal of Crohn's and Colitis . vol. 15 , s139 - s139 .

Klomberg R, Kemos P, Aardoom M, Rizopoulos D, Croft N, de Ridder L, Neyt M ( 2021 ) . P114 Frequent work productivity and activity impairment in caregivers of children with inflammatory bowel disease: a project of the prospective PIBD-SETQuality inception cohort study . Journal of Crohn's and Colitis . vol. 15 , s206 - s207 .

Klomberg R, Aardoom M, Kemos P, Ruemmele F, Van Ommen CH, Croft NM, De Ridder L ( 2021 ) . 730 INCREASED RISK OF VENOUS THROMBOEMBOLISM IN PAEDIATRIC-ONSET INFLAMMATORY BOWEL DISEASE - A STUDY OF THE INTERNATIONAL PROSPECTIVE SAFETY REGISTRY . Gastroenterology . vol. 160 , s - 146 .

Klomberg R, Vuijk S, Kemos P, Aardoom M, Ruemmele F, Mulder J, Croft NM, De Ridder L ( 2021 ) . Su525 THE INCIDENCE AND CAUSES OF RENAL FAILURE IN PAEDIATRIC INFLAMMATORY BOWEL DISEASE - A PROJECT OF THE PIBD-SETQ SAFETY REGISTRY . Gastroenterology . vol. 160 ,

Thorn N, Vallorani M, Kirupananthan R, Kemos P, Croft N ( 2021 ) . P20 Emergenci: a UK prospective survey of severe GI bleeding (requiring upper GI endoscopy) and emergency endoscopy in under 16s . Frontline Gastroenterology . Conference: Poster presentations vol. 12 , a22 - a23 .

Heredia M, Charrout M, Klomberg RCW, Aardoom MA, Jongsma MME, Kemos P, van Haaften DH, Tuk B et al. ( 2021 ) . Circulating inflammatory protein and cellular profiles at time of diagnosis classify inflammatory bowel disease patients according to their underlying immune response and clinical disease course . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 275 - 275 .

Klomberg R, Aardoom M, Kemos P, Ruemmele F, Van Ommen CHH, Croft NM, De Ridder L ( 2021 ) . INCREASED RISK OF VENOUS THROMBOEMBOLISM IN PAEDIATRIC-ONSET INFLAMMATORY BOWEL DISEASE - A STUDY OF THE INTERNATIONAL PROSPECTIVE SAFETY REGISTRY . GASTROENTEROLOGY . vol. 160 , S146 - S146 .

Mecci J, Kemos P, Foster G ( 2021 ) . Patients with cirrhosis show an improvement in dynamic liver function following the eradication of hepatitis C virus with direct acting antivirals . JOURNAL OF HEPATOLOGY . vol. 75 , S790 - S791 .

Klomberg R, Vuijk S, Kemos P, Aardoom M, Ruemmele F, Mulder J, Croft NM, De Ridder L ( 2021 ) . THE INCIDENCE AND CAUSES OF RENAL FAILURE IN PAEDIATRIC INFLAMMATORY BOWEL DISEASE - A PROJECT OF THE PIBD-SETQ SAFETY REGISTRY . GASTROENTEROLOGY . vol. 160 , S726 - S727 .

Heredia M, Costes LMM, Tindemans I, Aardoom MA, Klomberg RCW, Kemos P, Joosse ME, Van Haaften DH et al. ( 2021 ) . TIGIT expression differentiates regulatory from inflammatory non-classical Th1-like gut-homing effector CD4+T cells in inflammatory bowel disease patients . EUROPEAN JOURNAL OF IMMUNOLOGY . vol. 51 , 29 - 29 .

Papachristos A, Kemos P, Kalofonos H, Sivolapenko G ( 2020 ) . In Reply . The Oncologist vol. 25 , ( 12 ) e2023 - e2023 .

Li W, Kemos P, Salciccioli JD, Marshall DC, Shalhoub J, Alazawi W ( 2020 ) . Socioeconomic Factors Associated With Liver-Related Mortality From 1985 to 2015 in 36 Developed Countries . Clinical Gastroenterology and Hepatology vol. 19 , ( 8 ) 1698 - 1707.e13 .

Aardoom MA, Kemos P, Tindemans I, Aloi M, Koletzko S, Levine A, Turner D, Veereman G et al. ( 2020 ) . International prospective observational study investigating the disease course and heterogeneity of paediatric-onset inflammatory bowel disease: the protocol of the PIBD-SETQuality inception cohort study . BMJ open vol. 10 , ( 7 ) e035538 - e035538 .

Papachristos A, Kemos P, Kalofonos H, Sivolapenko G ( 2020 ) . VEGF-A polymorphisms affect the pharmacologic effect of bevacizumab on VEGF-A levels in patients with metastatic colorectal cancer . Journal of Clinical Oncology vol. 38 , ( 15_suppl ) e15505 - e15505 .

Aardoom M, Kemos P, Ruemmele F, van Ommen CH, Croft NM, de Ridder L ( 2020 ) . Mo1900 THE INCIDENCE AND CHARACTERISTICS OF VENOUS THROMBOEMBOLISMS IN PEDIATRIC-ONSET INFLAMMATORY BOWEL DISEASE . Gastroenterology . vol. 158 , s - 970 .

Papachristos A, Kemos P, Kalofonos H, Sivolapenko G ( 2020 ) . Correlation Between Bevacizumab Exposure and Survival in Patients with Metastatic Colorectal Cancer . The Oncologist vol. 25 , ( 10 ) 853 - 858 .

Costes L, Tindemans I, Joosse ME, Aardoom MA, Jongsma MME, Raatgeep RHC, van Haaften DH, Alexander KL et al. ( 2020 ) . DOP09 IgG responses to multiple bacterial flagellins identify a subgroup of paediatric therapy-naive Crohn’s disease patients with increased microbiota-specific T-cell reactivity . Journal of Crohn's and Colitis . vol. 14 , s046 - s046 .

Aardoom M, Kemos P, Ruemmele FM, van Ommen CH, Croft NM, de Ridder L ( 2020 ) . P116 The occurrence of venous thromboembolisms in paediatric-onset IBD . Journal of Crohn's and Colitis . vol. 14 , s194 - s194 .

Papachristos A, Kemos P, Kalofonos H, Sivolapenko G ( 2020 ) . <i>VEGF</i>-<i>A</i> polymorphisms affect the pharmacologic effect of bevacizumab on VEGF-A levels in patients with metastatic colorectal cancer . JOURNAL OF CLINICAL ONCOLOGY . vol. 38 ,

Costes L, Tindemans I, Joosse ME, Aardoom MA, Jongsma MME, Raatgeep RHC, van Haaften DH, Alexander KL et al. ( 2020 ) . IgG responses to multiple bacterial flagellins identify a subgroup of paediatric therapynaive Crohn's disease patients with increased microbiota-specific T-cell reactivity . JOURNAL OF CROHNS & COLITIS . vol. 14 , S046 - S046 .

Aardoom M, Kemos P, Ruemmele F, van Ommen CHH, Croft NM, de Ridder L ( 2020 ) . THE INCIDENCE AND CHARACTERISTICS OF VENOUS THROMBOEMBOLISMS IN PEDIATRIC-ONSET INFLAMMATORY BOWEL DISEASE .

Aardoom M, Kemos P, Ruemmele FM, van Ommen CH, Croft NM, de Ridder L ( 2020 ) . The occurrence of venous thromboembolisms in paediatric-onset IBD . JOURNAL OF CROHNS & COLITIS . vol. 14 , S194 - S194 .

Papachristos A, Kemos P, Katsila T, Panoilia E, Patrinos GP, Kalofonos H, Sivolapenko GB ( 2019 ) . VEGF-A and ICAM-1 Gene Polymorphisms as Predictors of Clinical Outcome to First-Line Bevacizumab-Based Treatment in Metastatic Colorectal Cancer . International Journal of Molecular Sciences vol. 20 , ( 22 )

Mecci AJ, Kemos P, Leen C, Lawson A, Richardson P, Khakoo SI, Agarwal K, Mutimer D et al. ( 2019 ) . The association between hepatocellular carcinoma and direct‐acting anti‐viral treatment in patients with decompensated cirrhosis . Alimentary Pharmacology & Therapeutics vol. 50 , ( 2 ) 204 - 214 .

Rao A, Kemos P, Kamperidis N, Naik S, Croft NM, Sanderson I ( 2019 ) . CHILDREN WITH CROHN'S DISEASE WHO RESPOND TO AN ENTERAL DIET ARE TWICE AS LIKELY TO REMAIN IN CLINICAL REMISSION OVER 5 YEARS . GASTROENTEROLOGY . Conference: Digestive Diseases Week (American Gastroenterological Association) vol. 156 , S615 - S616 .

Vavilikolanu R, Sanderson I, Naik S, Croft NM, Kemos P ( 2019 ) . G118(P) The risk of nephrotoxicity from 5-ASA in children with ulcerative colitis (UC) is not dose related . Archives of Disease in Childhood . Conference: Royal College of Paediatrics and Child Health vol. 104 , a48 - a48 .

Rao A, Kemos P, Kamperidis N, Naik S, Croft NM, Sanderson I ( 2019 ) . Su1797 – Children with Crohn’s Disease Who Respond to an Enteral Diet are Twice As Likely to Remain in Clinical Remission Over 5 Years . Gastroenterology . vol. 156 ,

Waller K, Jong AV-D, Li W, Lowe R, Kemos P, Syn W-K, Alazawi W ( 2019 ) . FRI-356-Single cell peripheral innate and adaptive immune signature of non-alcoholic steatohepatitis by cytometry time of flight . Journal of Hepatology . vol. 70 , e551 - e552 .

Mecci J, Maxan M-E, Kemos P, Telfer P, Barroso F, Foster G, Banu K ( 2019 ) . FRI-437-Diagnosis of sickle cell liver disease may be aided by non-invasive tests . Journal of Hepatology . vol. 70 , e586 - e587 .

Aardoom MA, Kemos P, Ruemmele F, Tindemans I, Samsom JN, Croft N, de Ridder L ( 2019 ) . P165 A global prospective observational study in children and adolescents with paediatric-onset IBD: the PIBD-SETQuality inception cohort . Journal of Crohn's and Colitis . vol. 13 , s171 - s172 .

Aardoom MA, Kemos P, Ruemmele F, Croft N, de Ridder L ( 2019 ) . P596 An ongoing safety registry to identify rare and severe complications in children with paediatric-onset IBD . Journal of Crohn's and Colitis . vol. 13 , s413 - s413 .

Joosse ME, Aardoom MA, Kemos P, Turner D, Wilson DC, Koletzko S, Martin‐de‐Carpi J, Fagerberg UL et al. ( 2018 ) . Malignancy and mortality in paediatric‐onset inflammatory bowel disease: a 3‐year prospective, multinational study from the paediatric IBD Porto group of ESPGHAN . Alimentary Pharmacology & Therapeutics vol. 48 , ( 5 ) 523 - 537 .

Ballard C, Banister C, Khan Z, Cummings J, Demos G, Coate B, Youakim JM, Owen R et al. ( 2018 ) . Evaluation of the safety, tolerability, and efficacy of pimavanserin versus placebo in patients with Alzheimer's disease psychosis: a phase 2, randomised, placebo-controlled, double-blind study . The Lancet Neurology vol. 17 , ( 3 ) 213 - 222 .

Aardoom M, Kemos P, Ruemmele F, Croft N, de Ridder L, consortium and PIBDnet OBOTPS ( 2018 ) . P584 Rare and severe complications in children with paediatric-onset IBD; the international PIBD SETQuality Safety Registry by PIBDnet . Journal of Crohn's and Colitis . vol. 12 , s403 - s404 .

Kemos P, Aardoom M, Ruemmele F, de Ridder L, Croft N, consortium and PIBDnet OBOTPS ( 2018 ) . P785 Designing the first pan-European paediatric IBD database to allow the study of incidence and prevalence of UC, CD, and their rare and severe complications . Journal of Crohn's and Colitis . vol. 12 , s508 - s508 .

Kemos P, Aardoom M, Ruemmele F, de Ridder L, Croft N ( 2018 ) . Designing the first pan-European paediatric IBD database to allow the study of incidence and prevalence of UC, CD, and their rare and severe complications . JOURNAL OF CROHNS & COLITIS . vol. 12 , S508 - S508 .

Dolman G, Saleh H, Kemos P, Kennedy PTF ( 2018 ) . Quantitative Hepatitis B Surface Antigen (qHBsAg) Has Poor Performance As a Marker of High Risk Antenatal Chronic Hepatitis B (CHB) in a Multi-Ethnic Population . HEPATOLOGY . vol. 68 , 1187A - 1188A .

Aardoom M, Kemos P, Ruemmele F, Croft N, de Ridder L ( 2018 ) . Rare and severe complications in children with paediatric-onset IBD; the international PIBD SETQuality Safety Registry by PIBDnet . JOURNAL OF CROHNS & COLITIS . vol. 12 , S403 - S404 .

Alazawi W, Bernabe E, Tai D, Janicki T, Kemos P, Samsuddin S, Syn W-K, Gillam D et al. ( 2017 ) . Periodontitis is associated with significant hepatic fibrosis in patients with non-alcoholic fatty liver disease . PLoS One vol. 12 , ( 12 ) e0185902 - e0185902 .

De Silva S, Li W, Kemos P, Brindley JH, Mecci J, Samsuddin S, Chin-Aleong J, Feakins RM et al. ( 2017 ) . Non-invasive markers of liver fibrosis in fatty liver disease are unreliable in people of South Asian descent . Frontline Gastroenterology vol. 9 , ( 2 )

De Silva S, Li W, Kemos P, Brindley J, Mecci J, Samsuddin S, Chin-Aleong J, Feakins R et al. ( 2017 ) . PWE-075 Non-invasive markers of liver fibrosis in fatty liver disease are unreliable in people of south asian descent . Gut . Conference: Liver vol. 66 ,

De Silva S, Li W, Kemos P, Brindley JH, Feakins R, Chinaleong J, Samsuddin S, Foster GR et al. ( 2017 ) . SAT-320 Blood-test based assessment of liver fibrosis, but not transient elastography, is less accurate in NAFLD patients of South Asian compared to White ethnicity . Journal of Hepatology . vol. 66 , s595 - s596 .

Alazawi W, Tai DF, Kemos P, Bernabe E, Janicki T, Gillam D, Samsuddin S, Syn WK et al. ( 2017 ) . SAT-321 Periodontitis is strongly associated with NAFLD in the NHANES III cohort and in an independent prospective study, is more common in those with biopsy-proven advanced compared to mild liver disease . Journal of Hepatology . vol. 66 ,